PCIDB

KNApSAcK Metabolite C00008956

Metabolite

KNApSAcK Entry

id C00008956
Name Dihydrodaphnodorin B
CAS RN 160023-57-4
Standard InChI InChI=1S/C30H24O10/c31-15-5-1-13(2-6-15)28-22(37)11-18-19(34)12-23-25(30(18)40-28)26(29(39-23)14-3-7-16(32)8-4-14)27(38)24-20(35)9-17(33)10-21(24)36/h1-10,12,22,26,28-29,31-37H,11H2/t22-,26?,28+,29?/m0/s1
Standard InChI (Main Layer) InChI=1S/C30H24O10/c31-15-5-1-13(2-6-15)28-22(37)11-18-19(34)12-23-25(30(18)40-28)26(29(39-23)14-3-7-16(32)8-4-14)27(38)24-20(35)9-17(33)10-21(24)36/h1-10,12,22,26,28-29,31-37H,11H2

Cluster

Phytochemical cluster No. 19
KCF-S cluster No. 16

Link

ChEMBL

By standard InChI CHEMBL1532097
By standard InChI Main Layer CHEMBL1532097

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count
rosids 1

Family

family name count
Thymelaeaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Wikstroemia sikokiana 142693 Thymelaeaceae rosids Viridiplantae

Human Protein / Gene in interaction

19 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein CHEMBL1532097 CHEMBL1738312 (1)
0 / 0
P39900 Macrophage metalloelastase M10A CHEMBL1532097 CHEMBL2051216 (1)
0 / 0
P14780 Matrix metalloproteinase-9 M10A CHEMBL1532097 CHEMBL2051215 (1) CHEMBL2051221 (1)
2 / 2
P07237 Protein disulfide-isomerase Enzyme CHEMBL1532097 CHEMBL1964080 (1) CHEMBL2114805 (1)
0 / 0
P11473 Vitamin D3 receptor NR1I1 CHEMBL1532097 CHEMBL1794311 (1)
2 / 3
P39748 Flap endonuclease 1 Enzyme CHEMBL1532097 CHEMBL1794486 (1)
0 / 0
P03956 Interstitial collagenase M10A CHEMBL1532097 CHEMBL2051212 (1)
0 / 1
Q9Y253 DNA polymerase eta Enzyme CHEMBL1532097 CHEMBL1794569 (1)
1 / 1
P09923 Intestinal-type alkaline phosphatase Enzyme CHEMBL1532097 CHEMBL1738679 (1)
0 / 0
P05186 Alkaline phosphatase, tissue-nonspecific isozyme Enzyme CHEMBL1532097 CHEMBL1738602 (1)
3 / 1
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein CHEMBL1532097 CHEMBL1614280 (1)
0 / 0
P45452 Collagenase 3 M10A CHEMBL1532097 CHEMBL2051217 (1) CHEMBL2051223 (1)
1 / 1
P10696 Alkaline phosphatase, placental-like Enzyme CHEMBL1532097 CHEMBL1738040 (1)
0 / 1
P08253 72 kDa type IV collagenase M10A CHEMBL1532097 CHEMBL2051213 (1) CHEMBL2051219 (1)
1 / 3
Q9UNA4 DNA polymerase iota Enzyme CHEMBL1532097 CHEMBL1794483 (1)
0 / 0
O75164 Lysine-specific demethylase 4A Enzyme CHEMBL1532097 CHEMBL1737991 (1)
0 / 0
P08254 Stromelysin-1 M10A CHEMBL1532097 CHEMBL2051214 (1) CHEMBL2051220 (1)
1 / 0
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL1532097 CHEMBL1794536 (1)
0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme CHEMBL1532097 CHEMBL2114796 (1)
2 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (13)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc Q14191
#614466 Coronary heart disease, susceptibility to, 6; chds6 P08254
#146300 Hypophosphatasia, adult P05186
#241510 Hypophosphatasia, childhood P05186
#241500 Hypophosphatasia, infantile P05186
#603932 Intervertebral disc disease; idd P14780
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#602111 Spondyloepimetaphyseal dysplasia, missouri type P45452
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (11)

KEGG disease name UniProt
H00028 Choriocarcinoma P03956 (related)
P08253 (related)
H00213 Hypophosphatasia P05186 (related)
H00025 Penile cancer P08253 (related)
P14780 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00023 Testicular cancer P10696 (marker)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00479 Metaphyseal dysplasias P14780 (related)
P45452 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)