Organism name | Wikstroemia sikokiana |
---|---|
Genus | Wikstroemia |
Family | Thymelaeaceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Wikstroemia |
---|---|
Linked NCBI taxonomy ID | 142693 |
Linked level | genus |
Family in NCBI taxonomy | Thymelaeaceae |
---|---|
ID | 39987 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | rosids |
---|---|
ID | 71275 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00008956
![]() |
Dihydrodaphnodorin B
|
CHEMBL1532097
|
19 / 13 / 11 | No. 16 | No. 19 |
![]() |
||
C00007190
![]() |
(+)-Pinoresinol
|
CHEMBL267963
CHEMBL487611 CHEMBL460862 |
C103298
|
7 / 5 / 6 | No. 38 | No. 21 |
![]() |
|
C00006421
![]() |
Neochamaejasmin B
|
CHEMBL467196
CHEMBL452374 |
1 / 0 / 0 | No. 57 | No. 18 |
![]() |
||
C00000972
![]() |
Isochamaejasmin
|
CHEMBL467196
CHEMBL452374 |
1 / 0 / 0 | No. 57 | No. 18 |
![]() |
||
C00006428
![]() |
Chamaejasmenin B
|
CHEMBL1545093
|
18 / 28 / 19 | No. 57 | No. 18 |
![]() |
||
C00006422
![]() |
Neochamaejasmin A
|
CHEMBL467196
CHEMBL452374 |
1 / 0 / 0 | No. 57 | No. 18 |
![]() |
||
C00006424
![]() |
Sikokianin C
|
CHEMBL1172171
CHEMBL1172216 |
No. 57 | No. 18 |
![]() |
|||
C00006425
![]() |
Sikokianin B
|
CHEMBL1172171
CHEMBL1172216 |
No. 57 | No. 18 |
![]() |
|||
C00006427
![]() |
Chamaejasmenin A
|
CHEMBL1545093
|
18 / 28 / 19 | No. 57 | No. 18 |
![]() |
||
C00006426
![]() |
Sikokianin A
/ (+)-Sikokianin A |
CHEMBL1172171
CHEMBL1172216 |
No. 57 | No. 18 |
![]() |
|||
C00008955
![]() |
Daphnodorin B
|
C055028
|
No. 88 |
![]() |
||||
C00008922
![]() |
Wikstrol A
|
No. 88 |
![]() |
|||||
C00008796
![]() |
Daphnodorin D1
|
CHEMBL1433872
|
10 / 6 / 4 | No. 88 |
![]() |
|||
C00007203
![]() |
(+)-Wikstromol
/ (+)-Nortrachelogenin |
CHEMBL453799
CHEMBL1483370 |
3 / 2 / 2 | No. 223 | No. 21 |
![]() |
||
C00000606
![]() |
(-)-Matairesinol
|
CHEMBL425148
|
C068935
|
1 / 0 / 0 | No. 223 | No. 21 |
![]() |
|
C00000604
![]() |
(-)-Secoisolariciresinol
|
CHEMBL368347
|
C060283
|
2 / 1 / 1 | 1 / 0 | No. 282 | No. 21 |
![]() |
C00000602
![]() |
(+)-Lariciresinol
|
CHEMBL518421
|
2 / 1 / 1 | No. 700 | No. 21 |
![]() |
||
C00011701
![]() |
[1S-(1R*,4S*,5E,7R*)]-4-Methyl-10-methylene-7-(1-methylethyl)-5-cyclodecene-1,4-diol
|
CHEMBL513802
|
No. 1547 |
![]() |
||||
C00008958
![]() |
Genkwanol B
|
No. 2864 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
O75164 | Lysine-specific demethylase 4A | Enzyme | C00006427 C00006428 C00008796 C00008956 | 0 / 0 |
P39748 | Flap endonuclease 1 | Enzyme | C00006427 C00006428 C00008796 C00008956 | 0 / 0 |
P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00006427 C00006428 C00008796 | 2 / 0 |
P05412 | Transcription factor AP-1 | Transcription Factor | C00000972 C00006421 C00006422 | 0 / 0 |
P37840 | Alpha-synuclein | Unclassified protein | C00006427 C00006428 | 4 / 2 |
O00255 | Menin | Unclassified protein | C00006427 C00006428 | 2 / 5 |
P06746 | DNA polymerase beta | Enzyme | C00006427 C00006428 | 0 / 0 |
O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00006427 C00006428 | 1 / 0 |
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000602 C00000604 | 1 / 0 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00006427 C00006428 | 4 / 3 |
Q99700 | Ataxin-2 | Unclassified protein | C00007203 C00008796 | 1 / 1 |
Q9UNA4 | DNA polymerase iota | Enzyme | C00008796 C00008956 | 0 / 0 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00006427 C00006428 | 1 / 2 |
P10828 | Thyroid hormone receptor beta | NR1A2 | C00006427 C00006428 | 3 / 1 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000602 C00000604 | 0 / 1 |
P54132 | Bloom syndrome protein | Enzyme | C00006427 C00006428 | 1 / 2 |
Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00007190 C00007203 | 0 / 0 |
Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00008796 C00008956 | 0 / 0 |
Q9Y253 | DNA polymerase eta | Enzyme | C00008796 C00008956 | 1 / 1 |
O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00006427 C00006428 | 0 / 0 |
P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00006427 C00006428 | 7 / 3 |
P42858 | Huntingtin | Unclassified protein | C00006427 C00006428 | 1 / 1 |
P17861 | X-box-binding protein 1 | Unclassified protein | C00006427 C00006428 | 1 / 0 |
O75496 | Geminin | Unclassified protein | C00006427 C00006428 | 0 / 0 |
P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00006427 C00006428 | 0 / 0 |
Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00006427 C00006428 | 1 / 1 |
Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00008796 | 0 / 0 |
P04278 | Sex hormone-binding globulin | Secreted protein | C00000606 | 0 / 0 |
P09923 | Intestinal-type alkaline phosphatase | Enzyme | C00008956 | 0 / 0 |
P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | Enzyme | C00008956 | 3 / 1 |
P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00008796 | 2 / 2 |
P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00007190 | 5 / 3 |
P45452 | Collagenase 3 | M10A | C00008956 | 1 / 1 |
P10696 | Alkaline phosphatase, placental-like | Enzyme | C00008956 | 0 / 1 |
P08253 | 72 kDa type IV collagenase | M10A | C00008956 | 1 / 3 |
P11473 | Vitamin D3 receptor | NR1I1 | C00008956 | 2 / 3 |
P07237 | Protein disulfide-isomerase | Enzyme | C00008956 | 0 / 0 |
Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00008796 | 0 / 0 |
P14780 | Matrix metalloproteinase-9 | M10A | C00008956 | 2 / 2 |
Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00007190 | 0 / 0 |
Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00007190 | 0 / 0 |
P39900 | Macrophage metalloelastase | M10A | C00008956 | 0 / 0 |
P08254 | Stromelysin-1 | M10A | C00008956 | 1 / 0 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00008956 | 0 / 0 |
P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00007203 | 1 / 1 |
P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00007190 | 0 / 3 |
P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00007190 | 0 / 0 |
Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00008956 | 0 / 0 |
Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00007190 | 0 / 0 |
Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00008956 | 2 / 1 |
P03956 | Interstitial collagenase | M10A | C00008956 | 0 / 1 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
8856 | NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR | nuclear receptor subfamily 1, group I, member 2 |
C00000604
|
OMIM | preferred title | UniProt |
---|---|---|
#219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
#612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
#210900 | Bloom syndrome; blm |
P54132
|
%606641 | Body mass index; bmi |
P37231
|
#609338 | Carotid intimal medial thickness 1 |
P37231
|
#114500 | Colorectal cancer; crc |
P84022
Q14191 |
#614466 | Coronary heart disease, susceptibility to, 6; chds6 |
P08254
|
#127750 | Dementia, lewy body; dlb |
P37840
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#137800 | Glioma susceptibility 1; glm1 |
O75874
P37231 |
#232300 | Glycogen storage disease ii |
P10253
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#143100 | Huntington disease; hd |
P42858
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#146300 | Hypophosphatasia, adult |
P05186
|
#241510 | Hypophosphatasia, childhood |
P05186
|
#241500 | Hypophosphatasia, infantile |
P05186
|
#603932 | Intervertebral disc disease; idd |
P14780
|
#604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
#613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
#612371 | Major affective disorder 7; mafd7 |
P17861
|
#174800 | Mccune-albright syndrome; mas |
P63092
|
#613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
#259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
#257200 | Niemann-pick disease, type a |
P17405
|
#607616 | Niemann-pick disease, type b |
P17405
|
#601665 | Obesity |
P37231
|
#166350 | Osseous heteroplasia, progressive; poh |
P63092
|
#168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
#605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
#168600 | Parkinson disease, late-onset; pd |
P37840
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#172700 | Pick disease of brain |
P10636
|
#102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
#103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
#603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
#612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
#183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
#602111 | Spondyloepimetaphyseal dysplasia, missouri type |
P45452
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
#274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
#145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
#277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
#277700 | Werner syndrome; wrn |
Q14191
|
#278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
|
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H00028 | Choriocarcinoma |
P03956
(related)
P08253 (related) |
H00213 | Hypophosphatasia |
P05186
(related)
|
H00025 | Penile cancer |
P08253
(related)
P14780 (related) P35354 (related) |
H00472 | Torg-Winchester syndrome |
P08253
(related)
|
H00036 | Osteosarcoma |
P08684
(marker)
|
H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00023 | Testicular cancer |
P10696
(marker)
|
H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
H00342 | Tuberculosis |
P11473
(related)
|
H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
H00479 | Metaphyseal dysplasias |
P14780
(related)
P45452 (related) |
H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
H00017 | Esophageal cancer |
P35354
(related)
|
H00046 | Cholangiocarcinoma |
P35354
(related)
|
H00032 | Thyroid cancer |
P37231
(related)
|
H00409 | Type II diabetes mellitus |
P37231
(related)
|
H00420 | Familial partial lipodystrophy (FPL) |
P37231
(related)
|
H00057 | Parkinson's disease (PD) |
P37840
(related)
|
H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
H00059 | Huntington's disease (HD) |
P42858
(related)
|
H00094 | DNA repair defects |
P54132
(related)
|
H00296 | Defects in RecQ helicases |
P54132
(related)
Q14191 (related) |
H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|