phytochemical cluster No. 18 (174 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• KCF-S cluster (3)
• Metabolite list (174)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

---

Cumulative plant class count

class name	count
Spermatophyta	284
rosids	168
Embryophyta	48
Magnoliophyta	7
asterids	6
Euphyllophyta	4
eudicotyledons	3
Liliopsida	1

---

Cumulative family count (Top 20)

class name	count
Cupressaceae	102
Araucariaceae	58
Podocarpaceae	52
Thymelaeaceae	33
Zamiaceae	27
Fabaceae	26
Ochnaceae	24
Clusiaceae	23
Taxaceae	20
Anacardiaceae	18
Rhamnaceae	12
Cycadaceae	11
Calophyllaceae	9
Selaginellaceae	9
Bartramiaceae	8
Aristolochiaceae	6
Mniaceae	6
Hypericaceae	5
Ginkgoaceae	5
Cephalotaxaceae	5

KEGG BRITE br08003

---

Categories (1)

br08003 Category	# of metabolite
Biflavonoids and polyflavonoids	11

---

metabolites link (12)

br08003 Category	KEGG ID	KNApSAcK ID
Biflavonoids and polyflavonoids	C09758	C00000972
Biflavonoids and polyflavonoids	C09761	C00000976
Biflavonoids and polyflavonoids	C09763	C00000978
Biflavonoids and polyflavonoids	C10017	C00001014
Biflavonoids and polyflavonoids	C10018	C00001015
Biflavonoids and polyflavonoids	C10034	C00001034
Biflavonoids and polyflavonoids	C10048	C00001044
Biflavonoids and polyflavonoids	C10057	C00001049
Biflavonoids and polyflavonoids	C10179	C00001094
Biflavonoids and polyflavonoids	C10182	C00001098
Biflavonoids and polyflavonoids	C10505	C00002549
Biflavonoids and polyflavonoids	C10018	C00042224

KCF-S cluster (3)

KCF-S ID	# of metabolite
No. 34	97
No. 57	70
No. 1327	7

Metabolite list (174)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	figure
C00042224	(S)-4'-Hydroxy-4-methoxydalbergione	CHEMBL255296 CHEMBL1374504		6 / 4 / 4		No. 34
C00041635	(R)-4-Methoxydalbergione	CHEMBL255297 CHEMBL466581 CHEMBL1554531		18 / 23 / 57		No. 34
C00037185	(R)-4'-Hydroxy-3,4-dimethoxydalbergione					No. 34
C00001014	Isoginkgetin	CHEMBL1208903		10 / 32 / 61		No. 34
C00001015	Amentoflavone 7'',4'''-dimethyl ether	CHEMBL374055		2 / 1 / 2		No. 34
C00001034	4',7''-Di-O-methylamentoflavone / Amentoflavone 4',7''-dimethyl ether	CHEMBL208988		1 / 0 / 0		No. 34
C00001044	Robustaflavone 7,4'-dimethyl ether	CHEMBL453554				No. 34
C00001049	Robustaflavone 4',7''-dimethyl ether					No. 34
C00001094	5'-Methoxybilobetin					No. 34
C00001098	7,7''-Di-O-methylagathisflavone					No. 34
C00035677	(rel)-1beta,2alpha-di-(2,4-dihydroxy-6-methoxybenzoyl)-3beta,4alpha-di-(4-methoxyphenyl)-cyclobutane					No. 34
C00034200	Mucronulatol-(4->6)-naringenin					No. 34
C00034199	Tetrahydrohinokiflavone / (-)-Tetrahydrohinokiflavone					No. 34
C00020669	Afzelone A					No. 34
C00019201	Hexaspermone B					No. 34
C00014733	Hexaspermone A					No. 34
C00014732	Dehydroxyhexaspermone C					No. 34
C00014729	Hexaspermone C					No. 34
C00014728	Chamaejasmenin C / Ruixianglangdusu A					No. 34
C00014707	Isochamaejasmin	CHEMBL467196 CHEMBL452374		1 / 0 / 0		No. 34
C00014700	Chamaejasmin	CHEMBL467196 CHEMBL452374		1 / 0 / 0		No. 34
C00006431	Robustaflavone 7''-methyl ether					No. 34
C00014697	Daphnodorin C		C055029			No. 34
C00014696	Daphnodorin I	CHEMBL1362112		14 / 20 / 16		No. 34
C00014695	Genkwanol A / [2'R-(2'alpha,3'beta,8'alpha,9'alpha)]-3',4'-Dihydro-3',4,5',6-tetrahydroxy-2',8'-bis(4-hydroxyphenyl)-spiro[benzofuran-2(3H),9'(8'H)-[2H]furo[2,3-h][1]benzopyran]-3-one	CHEMBL1362112	C054406	14 / 20 / 16		No. 34
C00014694	Daphnodorin G / [2S-(2alpha,3beta,7aalpha,13abeta)]-3,4,7a,13a-Tetrahydro-3,5,10,12,13a-pentahydroxy-2,7a-bis(4-hydroxyphenyl)-2H,13H-furo[2,3-b:5,4-h']bis[1]benzopyran-13-one					No. 34
C00006446	7-O-Methyl-6-C-methylamentoflavone					No. 34
C00006447	Ridiculuflavone D					No. 34
C00006448	Sciadopitysin	CHEMBL208908	C086243	3 / 3 / 7		No. 34
C00014693	Daphnodorin E	CHEMBL2048507		6 / 5 / 4		No. 34
C00006452	4',7,7''-Tri-O-methylamentoflavone / 7,4',7''-Tri-O-methylamentoflavone	CHEMBL208578		1 / 0 / 0		No. 34
C00006453	Kayaflavone	CHEMBL453479		1 / 0 / 0		No. 34
C00006454	Abiesin					No. 34
C00006455	7,7'',4'''-Tri-O-methylagathisflavone					No. 34
C00006456	Cupressuflavone 7,4',7''-trimethyl ether					No. 34
C00014688	Daphnogirin B	CHEMBL2048507		6 / 5 / 4		No. 34
C00006459	Stephaflavone B / 5,5'-Dihydroxy-2-(4-hydroxyphenyl)-7,7'-dimethoxy-2'-(4-methoxyphenyl)-[3,6'-bi-4H-1-benzopyran]-4,4'-dione					No. 34
C00006460	Stephaflavone A / 5,5'-Dihydroxy-7,7'-dimethoxy-2,2'-bis(4-methoxyphenyl)-[3,6'-bi-4H-1-benzopyran]-4,4'-dione					No. 34
C00006461	Agathisflavone tetramethyl ether					No. 34
C00006462	Cupressuflavone tetramethyl ether					No. 34
C00006463	Amentoflavone 7,4',7'',4'''-tetramethyl ether	CHEMBL378516		1 / 0 / 0		No. 34
C00006464	Olivieriflavone					No. 34
C00006465	Dioonflavone					No. 34
C00014687	Daphnogirin A	CHEMBL2048507		6 / 5 / 4		No. 34
C00006468	Neocryptomerin					No. 34
C00006472	Isocryptomerin					No. 34
C00006473	Cryptomerin A					No. 34
C00006475	Ochnaflavone 4'-methyl ether	CHEMBL188147				No. 34
C00006476	7''-O-Methylochnaflavone					No. 34
C00006477	Chamaecyparin					No. 34
C00006478	Cryptomerin B					No. 34
C00014685	(2R)-2-Deoxymaesopsin-(2->7)-(2S)-maesopsin					No. 34
C00014684	(2S)-2-Deoxymaesopsin-(2->7)-(2S)-maesopsin					No. 34
C00006483	Hinokiflavone	CHEMBL291426	C060299	2 / 1 / 2		No. 34
C00006484	Lanaroflavone	CHEMBL2172395				No. 34
C00006485	Delicaflavone / 3-[4-(5,7-Dihydroxy-4-oxo-4H-1-benzopyran-2-yl)phenoxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one					No. 34
C00006486	Loniflavone					No. 34
C00006487	Ochnaflavone	CHEMBL187504	C090940	3 / 0 / 0		No. 34
C00006488	Lophirone L					No. 34
C00006489	4''',5,5'',7''-Tetrahydroxy-3'',3''',4'-trimethoxy-6-O-alpha,7- beta-flavone-chalcone					No. 34
C00006490	4',5,5'',7''-Tetrahydroxy-3',3'',4'''-trimethoxy-6-O-alpha,7-beta-flavone-chalcone					No. 34
C00006491	3''',5,5'',7''-Tetrahydroxy-3'',4',4'''-trimethoxy-6-O-alpha,7-beta-flavone-chalcone					No. 34
C00006492	4',5,5'',7''-Tetrahydroxy-3',3'',4'''-trimethoxy-6-O-beta,7-alpha-flavone-chalcone					No. 34
C00006493	Cissampeloflavone					No. 34
C00006494	3''-Desoxydicranolomin / 6-[6-(5,7-Dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2,3-dihydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one					No. 34
C00006495	Sumaflavone	CHEMBL270509		1 / 1 / 3		No. 34
C00006496	5'-Hydroxyrobustaflavone					No. 34
C00006497	5'-Hydroxyamentoflavone					No. 34
C00006498	Moghatin / (+)-2-(3,4-Dihydroxyphenyl)-5,5',7,7'-tetrahydroxy-2'-(4-hydroxyphenyl)-[8,8'-bi-4H-1-benzopyran]-4,4'-dione					No. 34
C00006499	3'''-Hydroxyamentoflavone					No. 34
C00006500	Philonotisflavone-4'''-methyl ether					No. 34
C00006501	Dicranolomin		C421171			No. 34
C00006502	Philonotisflavone					No. 34
C00006503	5',3'''-Dihydroxyrobustaflavone	CHEMBL1990497				No. 34
C00006507	5',8''-Biluteolin					No. 34
C00006564	Tetrahydroamentoflavone					No. 34
C00014681	(2R,3S)-Naringenin-(3alpha->5)-(2S)-maesopsin					No. 34
C00014538	3,5,7,4',3'',5'',7''-Heptahydroxy-3'-O-4'''-biflavanone					No. 34
C00014537	Hypnogenol A					No. 34
C00014536	Hypnogenol B					No. 34
C00014535	[5',5']-Bisdihydroquercetin					No. 34
C00014534	3,5,7,4',3'',5'',7'',3''',4'''-Nonahydroxy-3',6''-biflavonone					No. 34
C00006598	Neorhusflavanone					No. 34
C00006585	Rhusflavanone	CHEMBL303495				No. 34
C00006566	3',3'''-Binaringenin	CHEMBL1779459				No. 34
C00006565	Biflavanone A					No. 34
C00006534	6''-(2-Hydroxy-3-methyl-3-butenyl)amentoflavone					No. 34
C00006535	8,'8''-Bibaicalein					No. 34
C00006536	Santarubin C					No. 34
C00006537	Pentagrametin					No. 34
C00006538	Strychnobiflavone					No. 34
C00006541	Pyranoamentoflavone 7,4'''-dimethyl ether					No. 34
C00006542	Pyranoamentoflavone 7,4'-dimethyl ether					No. 34
C00006543	Pyranoamentoflavone 7,4',4'''-Trimethyl ether					No. 34
C00006544	Pyranoamentoflavone					No. 34
C00006545	Globulixanthone E					No. 34
C00014683	(2R)-2-Deoxymaesopsin-(2->7)-(2R)-maesopsin					No. 34
C00006550	Tetrahydrorobustaflavone					No. 57
C00006546	Kudzuisoflavone A					No. 57
C00006532	6''-(3-Methyl-2-butenyl)amentoflavone					No. 57
C00006531	Anhydrobartramiaflavone					No. 57
C00006568	Jeediflavanone					No. 57
C00006569	Semecarpuflavanone					No. 57
C00006570	Galluflavanone					No. 57
C00006577	Succedaneaflavanone	CHEMBL66266 CHEMBL456858				No. 57
C00006530	3,8''-Biapigenin	CHEMBL515252		21 / 16 / 12		No. 57
C00006529	Cupressuflavone	CHEMBL1208973		6 / 1 / 1		No. 57
C00008795	Biflavanone C					No. 57
C00008797	(I-2S,II-2S)-I-7,II-7-Di-O-methyltetrahydroamentoflavone					No. 57
C00000972	Ginkgetin / 7,4'-Dimethylamentoflavone / Amentoflavone 7'',4'''-dimethyl ether	CHEMBL377324	C077458	1 / 0 / 0		No. 57
C00000976	7,7''-Di-O-methylamentoflavone	CHEMBL1208793		1 / 0 / 0		No. 57
C00037902	(S)-4-Methoxydalbergione	CHEMBL255297 CHEMBL466581 CHEMBL1554531		18 / 23 / 57		No. 57
C00000978	Putraflavone / Podocarpusflavone B	CHEMBL144630		1 / 0 / 0		No. 57
C00036356	(R)-3,4-Dimethoxydalbergione	CHEMBL1356393 CHEMBL1591258	C026197	16 / 37 / 63		No. 57
C00036031	(S)-3'-Hydroxy-4,4'-dimethoxydalbergione	CHEMBL1801609				No. 57
C00013286	GB1	CHEMBL504319	C055015			No. 57
C00013287	GB1a	CHEMBL63292 CHEMBL456859				No. 57
C00014530	GB-2a / (-)-GB-2a	CHEMBL63792 CHEMBL445452 CHEMBL446790				No. 57
C00006522	Agathisflavone	CHEMBL65320	C079168			No. 57
C00006521	Taiwaniaflavone	CHEMBL272861		1 / 1 / 3		No. 57
C00006520	Robustaflavone	CHEMBL63677		2 / 1 / 3		No. 57
C00006519	Amenthoflavone	CHEMBL63354		50 / 39 / 29		No. 57
C00006518	Amentoflavone	CHEMBL63354	C011164	50 / 39 / 29	5 / 0	No. 57
C00014674	(2S,3R)-Dihydrogenistein-(2alpha->7)-(2R)-maesopsin					No. 57
C00014675	Zeyherin					No. 57
C00014676	(2S,3R)-Dihydrogenistein-(2alpha->7)-(2S)-maesopsin					No. 57
C00014677	[2R-[2alpha,3beta(S*)]]-3-[2,3-Dihydro-2,4,6-trihydroxy-2-[(4-hydroxyphenyl)methyl]-3-oxo-7-benzofuranyl]-2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one					No. 57
C00014678	[2R-[2alpha,3beta(R*)]]-3-[2,3-Dihydro-2,4,6-trihydroxy-2-[(4-hydroxyphenyl)methyl]-3-oxo-7-benzofuranyl]-2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one					No. 57
C00014679	(2R,3S)-Naringenin-(3alpha->5)-(2R)-maesopsin					No. 57
C00006517	Heterobryoflavone					No. 57
C00006516	Bryoflavone					No. 57
C00006482	Ochnaflavone 7,4'-dimethyl ether					No. 57
C00006481	5-Hydroxy-7-methoxyflavone-(4' ->O-> 8'')-5'',7''-dihydroxy-4'''-methoxyflavone					No. 57
C00014686	(2S)-2-Deoxymaesopsin-(2->7)-(2R)-maesopsin					No. 57
C00006467	5-Hydroxy-7-methoxyflavone-(4' ->O -> 8'')-4''',5'',7''-trihydroxyflavone					No. 57
C00006458	Ridiculuflavone C / (+)-Ridiculuflavone C					No. 57
C00006451	Heveaflavone	CHEMBL1208904		1 / 0 / 0		No. 57
C00006443	7-O-Methylagathisflavone					No. 57
C00006442	7''-Methylagathisflavone					No. 57
C00006441	7-O-Methylcupressuflavone					No. 57
C00006439	4'-O-Methylcupressuflavone					No. 57
C00006429	Robustaflavone 4'-methyl ether	CHEMBL451902				No. 57
C00014704	Neochamaejasmin B	CHEMBL467196 CHEMBL452374		1 / 0 / 0		No. 57
C00014706	Neochamaejasmin A	CHEMBL467196 CHEMBL452374		1 / 0 / 0		No. 57
C00006428	Sequoiaflavone	CHEMBL255493		1 / 0 / 0		No. 57
C00014708	Sikokianin C	CHEMBL1172171 CHEMBL1172216				No. 57
C00014709	Sikokianin B	CHEMBL1172171 CHEMBL1172216				No. 57
C00014710	Sikokianin A / (+)-Sikokianin A	CHEMBL1172171 CHEMBL1172216				No. 57
C00014711	7-Methylchamaejasmin					No. 57
C00014718	Isochamaejasmenin B	CHEMBL1545093		18 / 28 / 19		No. 57
C00014719	Chamaejasmenin B	CHEMBL1545093		18 / 28 / 19		No. 57
C00014720	Chamaejasmenin A	CHEMBL1545093		18 / 28 / 19		No. 57
C00014726	Chamaejasmenin D / (+)-Chamaejasmenin D					No. 57
C00014727	Ruixianglangdusu B / (2R,2'R,3S,3'S)-rel-(+)-2,2',3,3'-Tetrahydro-5,5',7-trihydroxy-7'-methoxy-2,2'-bis(4-methoxyphenyl)-[3,3'-bi-4H-1-benzopyran]-4,4'-dione					No. 57
C00036030	(S)-4,4'-Dimethoxydalbergione	CHEMBL1436980		14 / 11 / 10		No. 57
C00006426	Sotetsuflavone	CHEMBL450522		1 / 0 / 0		No. 57
C00006425	Bilobetin	CHEMBL378188		2 / 1 / 2		No. 57
C00006424	Taiwaniaflavone 4',7''-dimethyl ether					No. 57
C00006423	Taiwaniaflavone 7''-O-methyl ether					No. 57
C00006422	4',4'''-Di-O-methylcupressuflavone					No. 57
C00030090	Afzelone B					No. 57
C00030091	7-O-Methyltetrahydroochnaflavone	CHEMBL451877				No. 57
C00031675	7,7''Di-O-methyl-2,3,2'',3''-tetrahydroochnaflavone	CHEMBL448630				No. 57
C00031893	7,7''-Di-O-Methyltetrahydrohinokiflavone					No. 57
C00006421	7,7''-Di-O-methylcupressuflavone					No. 57
C00006420	7,4'''-Di-O-Methylagathisflavone					No. 57
C00006427	Podocarpusflavone A	CHEMBL220745	C094150	2 / 1 / 2		No. 57
C00002549	6,6''-Bigenkwanin / 5,5'-Dihydroxy-2,2'-bis(4-hydroxyphenyl)-7,7'-dimethoxy-[6,6'-bi-4H-1-benzopyran]-4,4'-dione					No. 1327
C00010257	GB2	CHEMBL510563 CHEMBL508885	C055016			No. 1327
C00010256	Kolaflavanone					No. 1327
C00010255	Manniflavanone / Garciniflavanone					No. 1327
C00010254	Gnidia biflavonoid 4a / (2S,2'R,3R,3'R)-2,2',3,3'-Tetrahydro-3',5,5',7,7'-pentahydroxy-2-(4-hydroxyphenyl)-2'-(3,4,5-trihydroxyphenyl)-[3,8'-bi-4H-1-benzopyran]-4,4'-dione					No. 1327
C00010253	Gnidia biflavonoid 4 / (2R,2'R,3S,3'R)-2,2',3,3'-Tetrahydro-3',5,5',7,7'-pentahydroxy-2-(4-hydroxyphenyl)-2'-(3,4,5-trihydroxyphenyl)-[3,8'-bi-4H-1-benzopyran]-4,4'-dione					No. 1327
C00010252	7''-O-Methyltetrahydroamentoflavone					No. 1327

Human Protein / Gene in interactions

88 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P56817	Beta-secretase 1	A1A	C00001015 C00001034 C00001044 C00001049 C00001094 C00001098 C00006487 C00006488 C00006489 C00006490 C00006491 C00006492 C00006493 C00006494 C00006495 C00006498 C00006499 C00006500 C00006501 C00042224	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00001015 C00002549 C00006427 C00006428 C00006431 C00006494 C00010252 C00010253 C00010254 C00010255 C00013286 C00014530 C00031893 C00042224	4 / 3
O00255	Menin	Unclassified protein	C00001015 C00001098 C00002549 C00006427 C00006428 C00006494 C00010252 C00013286 C00014530 C00031893 C00042224	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00001015 C00001098 C00002549 C00006427 C00006428 C00006494 C00010252 C00013286 C00014530 C00031893 C00042224	1 / 2
Q9UBT6	DNA polymerase kappa	Enzyme	C00001015 C00001034 C00002549 C00006431 C00010252 C00010254 C00010255 C00013286 C00014530 C00042224	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00001015 C00001034 C00006427 C00006428 C00006431 C00013286 C00014530 C00031893 C00042224	0 / 0
P08253	72 kDa type IV collagenase	M10A	C00001015 C00001094 C00006446 C00006484 C00008797 C00030090 C00030091 C00042224	1 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00001015 C00002549 C00010252 C00010254 C00010255 C00013286 C00014530 C00042224	2 / 2
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00001015 C00006427 C00006428 C00013286 C00014530 C00031893 C00042224	7 / 3
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00001015 C00006427 C00006428 C00013286 C00014530 C00031893 C00042224	2 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002549 C00006431 C00006494 C00010252 C00010253 C00010254 C00010255	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00001015 C00001034 C00006431 C00013286 C00014530 C00042224	0 / 0
P43235	Cathepsin K	C1A	C00001015 C00001049 C00006488 C00006490 C00006495 C00042224	1 / 2
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002549 C00006431 C00010252 C00010253 C00010254 C00010255	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00001015 C00006427 C00006428 C00006431 C00031893 C00042224	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00002549 C00006494 C00010252 C00010253 C00010254 C00010255	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00006427 C00006428 C00006431 C00013286 C00014530 C00031893	1 / 1
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00002549 C00010252 C00010253 C00010254 C00010255	0 / 0
O75496	Geminin	Unclassified protein	C00001034 C00006427 C00006428 C00006431 C00031893	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00001015 C00006427 C00006428 C00031893 C00042224	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00001015 C00006427 C00006428 C00031893 C00042224	3 / 1
P00352	Retinal dehydrogenase 1	Enzyme	C00001015 C00002549 C00010252 C00010254 C00042224	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00001015 C00006427 C00006428 C00031893 C00042224	0 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00002549 C00010252 C00010253 C00010254 C00010255	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00001015 C00006431 C00013286 C00014530 C00042224	0 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00002549 C00010252 C00010254 C00010255	0 / 0
P05412	Transcription factor AP-1	Transcription Factor	C00000972 C00006420 C00006421 C00006422	0 / 0
P06746	DNA polymerase beta	Enzyme	C00006427 C00006428 C00006431 C00031893	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002549 C00010252 C00010254 C00010255	1 / 1
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002549 C00006494 C00010252 C00010255	3 / 3
P11473	Vitamin D3 receptor	NR1I1	C00002549 C00010252 C00010254 C00010255	2 / 3
Q9Y253	DNA polymerase eta	Enzyme	C00001015 C00001034 C00006431 C00042224	1 / 1
P54132	Bloom syndrome protein	Enzyme	C00006427 C00006428 C00006431 C00031893	1 / 2
P04637	Cellular tumor antigen p53	Transcription Factor	C00002549 C00006494 C00010252 C00010255	7 / 37
P03956	Interstitial collagenase	M10A	C00008797 C00030090 C00030091	0 / 1
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00001015 C00006431 C00042224	2 / 1
Q07820	Induced myeloid leukemia cell differentiation protein Mcl-1	Other cytosolic protein	C00001015 C00006431 C00042224	0 / 0
P42858	Huntingtin	Unclassified protein	C00006427 C00006428 C00031893	1 / 1
P17861	X-box-binding protein 1	Unclassified protein	C00006427 C00006428 C00031893	1 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00006427 C00006428 C00031893	1 / 0
P45452	Collagenase 3	M10A	C00008797 C00030090 C00030091	1 / 1
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00006431 C00013286 C00014530	0 / 0
O15496	Group 10 secretory phospholipase A2	Enzyme	C00001015 C00006542 C00042224	0 / 0
P08254	Stromelysin-1	M10A	C00008797 C00030090 C00030091	1 / 0
P14555	Phospholipase A2, membrane associated	Enzyme	C00001015 C00006542 C00042224	0 / 0
P39900	Macrophage metalloelastase	M10A	C00008797 C00030090 C00030091	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00008797 C00030090 C00030091	2 / 2
P37840	Alpha-synuclein	Unclassified protein	C00006427 C00006428 C00031893	4 / 2
P47712	Cytosolic phospholipase A2	Enzyme	C00001015 C00006542 C00042224	0 / 0
P19174	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	Enzyme	C00001015 C00042224	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00001015 C00042224	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00001015 C00042224	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00006494 C00010255	11 / 10
P49763	Placenta growth factor	Unclassified protein	C00001015 C00042224	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00013286 C00014530	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00001015 C00042224	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00013286 C00014530	1 / 1
P41143	Delta-type opioid receptor	Opioid receptor	C00001015 C00042224	0 / 0
P04062	Glucosylceramidase	Enzyme	C00006431 C00010255	6 / 4
P35462	D(3) dopamine receptor	Dopamine receptor	C00001015 C00042224	1 / 0
P47869	Gamma-aminobutyric acid receptor subunit alpha-2	GABA-A alpha	C00001015 C00042224	1 / 0
Q16445	Gamma-aminobutyric acid receptor subunit alpha-6	GABA-A alpha	C00001015 C00042224	0 / 0
P18054	Arachidonate 12-lipoxygenase, 12S-type	Enzyme	C00010254 C00010255	2 / 0
P55072	Transitional endoplasmic reticulum ATPase	Unclassified protein	C00001015 C00042224	2 / 1
P15692	Vascular endothelial growth factor A	Secreted protein	C00001015 C00042224	1 / 2
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00001015 C00042224	2 / 2
Q13951	Core-binding factor subunit beta	Unclassified protein	C00002549 C00010252	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00002549 C00010252	1 / 4
P18505	Gamma-aminobutyric acid receptor subunit beta-1	GABA-A beta	C00001015 C00042224	0 / 0
P28472	Gamma-aminobutyric acid receptor subunit beta-3	GABA-A beta	C00001015 C00042224	1 / 0
P14867	Gamma-aminobutyric acid receptor subunit alpha-1	GABA-A alpha	C00001015 C00042224	1 / 1
P48169	Gamma-aminobutyric acid receptor subunit alpha-4	GABA-A alpha	C00001015 C00042224	0 / 0
O14764	Gamma-aminobutyric acid receptor subunit delta	GABA-A delta	C00001015 C00042224	1 / 1
P31644	Gamma-aminobutyric acid receptor subunit alpha-5	GABA-A alpha	C00001015 C00042224	0 / 0
Q99928	Gamma-aminobutyric acid receptor subunit gamma-3	GABA-A gamma	C00001015 C00042224	0 / 0
P78334	Gamma-aminobutyric acid receptor subunit epsilon	GABA-A epsilon	C00001015 C00042224	0 / 0
Q8N1C3	Gamma-aminobutyric acid receptor subunit gamma-1	GABA-A gamma	C00001015 C00042224	0 / 0
P34903	Gamma-aminobutyric acid receptor subunit alpha-3	GABA-A alpha	C00001015 C00042224	0 / 0
O00591	Gamma-aminobutyric acid receptor subunit pi	GABA-A pi	C00001015 C00042224	0 / 0
P47870	Gamma-aminobutyric acid receptor subunit beta-2	GABA-A beta	C00001015 C00042224	0 / 0
P18507	Gamma-aminobutyric acid receptor subunit gamma-2	GABA-A gamma	C00001015 C00042224	4 / 2
Q9UN88	Gamma-aminobutyric acid receptor subunit theta	GABA-A theta	C00001015 C00042224	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00010254	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00006431	0 / 0
P63165	Small ubiquitin-related modifier 1	Unclassified protein	C00006431	1 / 1
P14618	Pyruvate kinase PKM	Enzyme	C00006431	0 / 0
P68871	Hemoglobin subunit beta	Secreted protein	C00006494	4 / 4
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00006431	0 / 0

5 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00001015
1638	DCT, TRP-2, TYRP2	dopachrome tautomerase (EC:5.3.3.12)	C00001015
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00001015
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00001015
7299	TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3	tyrosinase (EC:1.14.18.1)	C00001015

Related Diseases

Diseases related to proteins in ChEMBL interactions