PCIDB

KNApSAcK Metabolite C00023774

Metabolite

KNApSAcK Entry

id C00023774
Name Fucostanol / Stigmasterol / Dihydro-beta-sitosterol / (24S)24-Ethylcholestain-3beta-ol
CAS RN 83-48-7
Standard InChI InChI=1S/C29H48O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h8-10,19-21,23-27,30H,7,11-18H2,1-6H3/b9-8+/t20-,21-,23+,24+,25-,26+,27+,28+,29-/m1/s1
Standard InChI (Main Layer) InChI=1S/C29H48O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h8-10,19-21,23-27,30H,7,11-18H2,1-6H3

Cluster

Phytochemical cluster No. 11
KCF-S cluster No. 53

Link

ChEMBL

By standard InChI CHEMBL400247
By standard InChI Main Layer CHEMBL66943 CHEMBL186373 CHEMBL400247 CHEMBL1568947

KEGG

By LinkDB C05442

CTD

By CAS RN D013265

Species

Summary

Plant class

class name count
asterids 66
rosids 52
Magnoliophyta 12
Liliopsida 7
eudicotyledons 6
Embryophyta 4
Spermatophyta 2
Euphyllophyta 1

Family (Top 10)

family name count
Lamiaceae 18
Asteraceae 17
Fabaceae 14
Ebenaceae 13
Euphorbiaceae 5
Clusiaceae 5
Rutaceae 5
Annonaceae 4
Meliaceae 4
Piperaceae 3

List (162)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Ajuga taiwanensis 946572 Lamiaceae asterids Viridiplantae
Aleurites fordii Hemsl. 73154 Euphorbiaceae rosids Viridiplantae
Allanblackia floribunda 469914 Clusiaceae rosids Viridiplantae
Anisomeles indica 516069 Lamiaceae asterids Viridiplantae
Annona purpurea 1123437 Annonaceae Magnoliophyta Viridiplantae
Antrodia camphorata 196114 Coriolaceae Fungi
Aphanamixis polystachya 201010 Meliaceae rosids Viridiplantae
Aristolochia manshuriensis 158555 Aristolochiaceae Magnoliophyta Viridiplantae
Artabotrys uncinatus 225832 Annonaceae Magnoliophyta Viridiplantae
Artemisia annua L. 35608 Asteraceae asterids Viridiplantae
Artemisia sieversiana 205378 Asteraceae asterids Viridiplantae
Artemisia vulgaris 4220 Asteraceae asterids Viridiplantae
Asphodelus albus 207931 Xanthorrhoeaceae Liliopsida Viridiplantae
Asteracantha longifolia
Astragalus glycyphyllos 83862 Fabaceae rosids Viridiplantae
Aureoumbra lagunensis 44058 Eukaryota
Barringtonia racemosa 107821 asterids Viridiplantae
Bauhinia candicans 72379 Fabaceae rosids Viridiplantae
Bauhinia vahlii L. 3805 Fabaceae rosids Viridiplantae
Begonia nantoensis 78253 Begoniaceae rosids Viridiplantae
Blutaparon portulacoides 221763 Amaranthaceae eudicotyledons Viridiplantae
Boehmeria holosericea 83905 Urticaceae rosids Viridiplantae
Boehmeria tricuspis 644073 Urticaceae rosids Viridiplantae
Brosimum acutifolium 194252 Moraceae rosids Viridiplantae
Buddleja madagascariensis 26473 Scrophulariaceae asterids Viridiplantae
Butea monosperma 56060 Fabaceae rosids Viridiplantae
Caesalpinia minax 857496 Fabaceae rosids Viridiplantae
Calendula officinalis L. 41496 Asteraceae asterids Viridiplantae
Callicarpa pilosissima 21922 Lamiaceae asterids Viridiplantae
Caragana microphylla 220690 Fabaceae rosids Viridiplantae
Celtis laevigata 102692 Cannabaceae rosids Viridiplantae
Centrosema pubescens 185703 Fabaceae rosids Viridiplantae
Chamaecyparis formosensis 187461 Cupressaceae Spermatophyta Viridiplantae
Chorisia insignis 874444 Malvaceae rosids Viridiplantae
Chorisia speciosa 82382 Malvaceae rosids Viridiplantae
Cichorium intybus 13427 Asteraceae asterids Viridiplantae
Cinnamomum subavenium 977953 Lauraceae Magnoliophyta Viridiplantae
Cinnamosma madagascariensis 132965 Canellaceae Magnoliophyta Viridiplantae
Cleidion spiciflorum (Burm. f.) Merr. 212289 Euphorbiaceae rosids Viridiplantae
Clerodendron neutens 13432 Lamiaceae asterids Viridiplantae
Clerodendron serratum 13432 Lamiaceae asterids Viridiplantae
Corylus avellana 13451 Betulaceae rosids Viridiplantae
Corylus maxima 126985 Betulaceae rosids Viridiplantae
Couepia polyandra 82152 Chrysobalanaceae rosids Viridiplantae
Cussonia bancoensis 46390 Araliaceae asterids Viridiplantae
Dicteostelium discoideum
Dioscorea cyphocarpa 4672 Dioscoreaceae Liliopsida Viridiplantae
Diospyros buxifolia 589111 Ebenaceae asterids Viridiplantae
Diospyros castanea 413727 Ebenaceae asterids Viridiplantae
Diospyros cauliflora 413728 Ebenaceae asterids Viridiplantae
Diospyros curranii 413735 Ebenaceae asterids Viridiplantae
Diospyros diepenhorstii 413738 Ebenaceae asterids Viridiplantae
Diospyros ebenum 570484 Ebenaceae asterids Viridiplantae
Diospyros evena 13492 Ebenaceae asterids Viridiplantae
Diospyros kaki 35925 Ebenaceae asterids Viridiplantae
Diospyros mollis 268842 Ebenaceae asterids Viridiplantae
Diospyros montana 413762 Ebenaceae asterids Viridiplantae
Diospyros morrisiana 1008904 Ebenaceae asterids Viridiplantae
Diospyros sanza-minika 570493 Ebenaceae asterids Viridiplantae
Diospyros variegata 13492 Ebenaceae asterids Viridiplantae
Drypetes inaequalis 20145 Putranjivaceae rosids Viridiplantae
Dynamena pumila 308606 Sertulariidae Metazoa
Erythrina arborescens Roxb. 3841 Fabaceae rosids Viridiplantae
Erythrina indica 3845 Fabaceae rosids Viridiplantae
Eupatorium macrocephalum Lee. 13516 Asteraceae asterids Viridiplantae
Euphorbia indica 1046470 Euphorbiaceae rosids Viridiplantae
Euphorbia sessiliflora Roxb. 3977 Euphorbiaceae rosids Viridiplantae
Fagara heitzii 23513 Rutaceae rosids Viridiplantae
Frullania brasiliensis 264464 Frullaniaceae Embryophyta Viridiplantae
Frullania monocera 236963 Frullaniaceae Embryophyta Viridiplantae
Garcinia afzelii ENGL. 469917 Clusiaceae rosids Viridiplantae
Garcinia bancana MIQ 58227 Clusiaceae rosids Viridiplantae
Garcinia multiflora 1009474 Clusiaceae rosids Viridiplantae
Gentiana lutea L. 38851 Gentianaceae asterids Viridiplantae
Gleditsia sinensis Lam. 66096 Fabaceae rosids Viridiplantae
Glycine max 3847 Fabaceae rosids Viridiplantae
Gomphrena celosioides 217251 Amaranthaceae eudicotyledons Viridiplantae
Gonospermum gomerae 127983 Asteraceae asterids Viridiplantae
Guarea rhophalocarpa 43908 Meliaceae rosids Viridiplantae
Heliotropium indicum 248297 Boraginaceae asterids Viridiplantae
Heracleum wallichii 491186 Apiaceae asterids Viridiplantae
Herpetospermum caudigerum WALL 386181 Cucurbitaceae rosids Viridiplantae
Hertia cheirifolia 430993 Asteraceae asterids Viridiplantae
Heterothalamus spartioides 382002 Asteraceae asterids Viridiplantae
Hibiscus taiwanensis 47605 Malvaceae rosids Viridiplantae
Hordeum vulgare L.cv Mammut 4512 Poaceae Liliopsida Viridiplantae
Hypericum carinatum 55962 Hypericaceae rosids Viridiplantae
Inula cappa 313931 Asteraceae asterids Viridiplantae
Justicia heterocarpa T.ANDERS 4190 Acanthaceae asterids Viridiplantae
Kalanchoe spathulata 23012 Crassulaceae eudicotyledons Viridiplantae
Khaya ivorensis 486173 Meliaceae rosids Viridiplantae
Khaya senegalensis L. 124952 Meliaceae rosids Viridiplantae
Lanurocerasus officinalis
Laurencia obtusa 137763 Rhodomelaceae Eukaryota
Leonurus persicus 4137 Lamiaceae asterids Viridiplantae
Leucas cephalotes SPRENG. 378905 Lamiaceae asterids Viridiplantae
Libanotis intermedia
Loranthus falcatus 50141 Loranthaceae eudicotyledons Viridiplantae
Luvunga sarmentosa (Bl.) Kurz. 76969 Rutaceae rosids Viridiplantae
Lygodium flexuosum 85330 Lygodiaceae Euphyllophyta Viridiplantae
Melicope semecarpifolia 697038 Rutaceae rosids Viridiplantae
Moghania strobilifera
Monascus pilosus BCRC38072 147546 Elaphomycetaceae Fungi
Neolitsea acuminatissima 128654 Lauraceae Magnoliophyta Viridiplantae
Ocimum spicatum 39173 Lamiaceae asterids Viridiplantae
Oriciopsis glaberrima ENGL. 23513 Rutaceae rosids Viridiplantae
Paederia foetida 60087 Rubiaceae asterids Viridiplantae
Pentaphalangium solomonse Warb.
Physarum polycephalum 5791 Physaraceae Eukaryota
Piper kadsura 54803 Piperaceae Magnoliophyta Viridiplantae
Piper methysticum Forst.f. 13215 Piperaceae Magnoliophyta Viridiplantae
Piper nigrum L. 13216 Piperaceae Magnoliophyta Viridiplantae
Polyalthia longifolia var.pendula 105756 Annonaceae Magnoliophyta Viridiplantae
Polygala caudata 4275 Polygalaceae rosids Viridiplantae
Prosopis spicigera 1217432 Fabaceae rosids Viridiplantae
Pterocarpus santalinus 1071199 Fabaceae rosids Viridiplantae
Pterodon apraricioi 104317 Fabaceae rosids Viridiplantae
Pulicaria canariensis 73987 Asteraceae asterids Viridiplantae
Robinsonecio gerberifolius 98718 Asteraceae asterids Viridiplantae
Rubia wallichiana DECNE 25473 Rubiaceae asterids Viridiplantae
Rubia yunnanensis 25473 Rubiaceae asterids Viridiplantae
Ruellia tuberosa 441035 Acanthaceae asterids Viridiplantae
Salvia aegyptiaca 392645 Lamiaceae asterids Viridiplantae
Salvia officinalis 38868 Lamiaceae asterids Viridiplantae
Sambucus canadensis 57008 Adoxaceae asterids Viridiplantae
Sambucus nigra. 4201 Adoxaceae asterids Viridiplantae
Saussurea muliensis 254917 Asteraceae asterids Viridiplantae
Schistochila glaucescens 981197 Schistochilaceae Embryophyta Viridiplantae
Schleichera trijuga 290995 Sapindaceae rosids Viridiplantae
Scleropyrum wallichianum 364756 Cervantesiaceae eudicotyledons Viridiplantae
Senecio viravira 18794 Asteraceae asterids Viridiplantae
Sideritis argosphacelus var. spicata 155231 Lamiaceae asterids Viridiplantae
Sideritis candicans var.eriocephala 155231 Lamiaceae asterids Viridiplantae
Sideritis discolor 403019 Lamiaceae asterids Viridiplantae
Sideritis kuegleriana 403023 Lamiaceae asterids Viridiplantae
Sideritis lotsyi 403024 Lamiaceae asterids Viridiplantae
Sideritis lotsyi var. mascaensis 155231 Lamiaceae asterids Viridiplantae
Sideritis soluta 155263 Lamiaceae asterids Viridiplantae
Sideritis tenoi 155231 Lamiaceae asterids Viridiplantae
Solanum chacoense Bitt. 4107 Solanaceae asterids Viridiplantae
Spiraea formosana 409510 Rosaceae rosids Viridiplantae
Stemodia foliosa 225102 Plantaginaceae asterids Viridiplantae
Stemona collinsae 492015 Stemonaceae Liliopsida Viridiplantae
Stevia porphyrea 55669 Asteraceae asterids Viridiplantae
Strychnos dolychothyrsa 26496 Loganiaceae asterids Viridiplantae
Strychnos potatorum 85835 Loganiaceae asterids Viridiplantae
Tamus communis L. 55634 Dioscoreaceae Liliopsida Viridiplantae
Taraxacum formosanum 170733 Asteraceae asterids Viridiplantae
Taxus cuspidata 99806 Taxaceae Spermatophyta Viridiplantae
Ternstroemia gymnanthera 107827 Pentaphylacaceae asterids Viridiplantae
Tovomita brasiliensis 156484 Clusiaceae rosids Viridiplantae
Trichosanthes kirilowii 3677 Cucurbitaceae rosids Viridiplantae
Trigonostemon reidioides 289660 Euphorbiaceae rosids Viridiplantae
Tritomaria quinquedentata (Huds.) 248350 Scapaniaceae Embryophyta Viridiplantae
Tupistra chinensis 100497 Asparagaceae Liliopsida Viridiplantae
Ventilago leiocarpa 108868 Rhamnaceae rosids Viridiplantae
Virola surinamensis 224910 Myristicaceae Magnoliophyta Viridiplantae
Viscum coloratum 3971 Viscaceae eudicotyledons Viridiplantae
Xanthium strumarium 318068 Asteraceae asterids Viridiplantae
Xylopia aromatica 225838 Annonaceae Magnoliophyta Viridiplantae
Zanthoxylum integrifoliolum 67937 Rutaceae rosids Viridiplantae
Zea mays L. 4577 Poaceae Liliopsida Viridiplantae

Human Protein / Gene in interaction

5 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P06746 DNA polymerase beta Enzyme CHEMBL400247 CHEMBL921744 (1) CHEMBL921745 (1)
CHEMBL993810 (1)
0 / 0
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor CHEMBL400247 CHEMBL977664 (1)
0 / 0
P09884 DNA polymerase alpha catalytic subunit Transferase CHEMBL186373 CHEMBL830331 (1)
0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase CHEMBL186373 CHEMBL830332 (1)
0 / 0
Q02880 DNA topoisomerase 2-beta Isomerase CHEMBL186373 CHEMBL830332 (1)
0 / 0

CTD interaction (1)

compound gene gene name gene description interaction interaction type form reference
pmid
D013265 10599 SLCO1B1
HBLRR
LST-1
LST1
OATP-C
OATP1B1
OATP2
OATPC
SLC21A6
solute carrier organic anion transporter family, member 1B1 SLCO1B1 SNP results in increased abundance of Stigmasterol increases abundance
SNP 22022402