| Organism name | Salvia officinalis |
|---|---|
| Genus | Salvia |
| Family | Labiatae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Salvia officinalis |
|---|---|
| Linked NCBI taxonomy ID | 38868 |
| Linked level | species |
| Family in NCBI taxonomy | Lamiaceae |
|---|---|
| ID | 4136 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | asterids |
|---|---|
| ID | 71274 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00006229
|
Vicenin 2
/ Apigenin 6,8-di-C-glucoside |
CHEMBL1442950
|
6 / 14 / 8 | No. 1 | No. 15 |
|
||
|
C00001017
|
Cosmosiin
/ Apigenin 7-glucoside / (-)-Apigenin 7-glucoside / Apigenin 7-O-beta-D-glucopyranoside |
CHEMBL487995
CHEMBL487017 CHEMBL1591566 CHEMBL2165585 |
C057792
|
5 / 6 / 1 | No. 2 | No. 15 |
|
|
|
C00004388
|
6-Hydroxyluteolin 7-glucuronide
|
No. 2 | No. 15 |
|
||||
|
C00004268
|
Luteolin 7-glucuronide
/ Luteolin 7-O-glucuronide / Luteolin 7-O-beta-D-glucuronide |
CHEMBL464224
|
C075406
|
No. 2 | No. 15 |
|
||
|
C00004386
|
6-Hydroxyluteolin 7-O-beta-glucopyranoside:6-Hydroxyluteolin 7-glucoside
|
CHEMBL469621
|
No. 2 | No. 15 |
|
|||
|
C00004274
|
Luteolin 3'-O-beta-D-glucuronide
|
No. 2 | No. 15 |
|
||||
|
C00001016
|
7-O-Methylacacetin
/ Acacetin 7-methyl ether / Genkwanin 4'-methyl ether / Apigenin 7,4'-dimethyl ether / 5-Hydroxy-4',7-dimethoxyflavone / 5-Hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL350958
|
C044998
|
1 / 0 / 0 | No. 3 | No. 15 |
|
|
|
C00003837
|
Cirsimaritin
|
CHEMBL348436
|
C007072
|
13 / 18 / 14 | No. 3 | No. 15 |
|
|
|
C00003865
|
7-O-Methylluteolin
/ Luteolin 7-methyl ether / 5,3',4'-Trihydroxy-7-methoxyflavone / 2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one |
CHEMBL183745
|
C051414
|
1 / 1 / 2 | No. 3 | No. 15 |
|
|
|
C00001033
|
Cirsiliol
|
CHEMBL72637
|
C039824
|
2 / 4 / 4 | 2 / 0 | No. 3 | No. 15 |
|
|
C00001050
|
Dinatin
/ Hispidulin / 6-Methoxyapigenin / 6-O-Methylapigenin |
CHEMBL293776
|
C055957
|
32 / 34 / 59 | 0 / 1 | No. 3 | No. 15 |
|
|
C00001043
|
Genkwanin
|
CHEMBL210635
|
C014568
|
5 / 4 / 5 | 3 / 0 | No. 3 | No. 15 |
|
|
C00019064
|
Oleanolic acid
/ Astrantiagenin C / Virgaureagenin B / 3beta-Hydroxyolean-12-en-28-oic acid |
CHEMBL56615
CHEMBL168 CHEMBL180553 CHEMBL365375 CHEMBL486382 CHEMBL1413646 CHEMBL1436454 |
D009828
|
30 / 8 / 12 | 21 / 15 | No. 13 | No. 51 |
|
|
C00003749
|
Lupeol
/ Lupenol / (+)-Lupenol |
CHEMBL289191
CHEMBL459702 |
C010480
|
3 / 0 / 0 | 2 / 6 | No. 23 | No. 51 |
|
|
C00000968
|
Hesperetin
|
CHEMBL88169
CHEMBL399121 CHEMBL1589200 |
C013015
|
42 / 50 / 65 | 18 / 3 | No. 25 | No. 14 |
|
|
C00003840
|
Salvigenin
|
CHEMBL376644
|
C014049
|
No. 35 | No. 15 |
|
||
|
C00019420
|
Physcion
/ 1,8-Dihydroxy-3-methyl-6-methoxyanthraquinone |
CHEMBL42624
|
C008905
|
18 / 20 / 14 | 1 / 0 | No. 41 | No. 62 |
|
|
C00002707
|
Picein
/ 4-Hydroxyacetophenone 4-glucoside |
CHEMBL1512620
|
C050880
|
3 / 0 / 0 | No. 45 | No. 72 |
|
|
|
C00003672
|
Sitosterol
/ beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol |
CHEMBL221542
CHEMBL1398443 CHEMBL1875388 |
17 / 19 / 12 | No. 53 | No. 11 |
|
||
|
C00023774
|
Fucostanol
/ Stigmasterol / Dihydro-beta-sitosterol / (24S)24-Ethylcholestain-3beta-ol |
CHEMBL66943
CHEMBL186373 CHEMBL400247 CHEMBL1568947 |
D013265
|
5 / 0 / 0 | 1 / 0 | No. 53 | No. 11 |
|
|
C00003817
|
Apigenin
/ 5,7,4'-Trihydroxyflavone |
CHEMBL28
|
D047310
|
164 / 119 / 105 | 68 / 8 | No. 71 | No. 15 |
|
|
C00000674
|
Luteolin
|
CHEMBL151
|
D047311
|
99 / 91 / 95 | 76 / 6 | No. 71 | No. 15 |
|
|
C00003834
|
Scutellarein
/ 6-Hydroxyapigenin |
CHEMBL55415
|
C458179
|
21 / 13 / 7 | 3 / 1 | No. 71 | No. 15 |
|
|
C00003848
|
Isoscutellarein
/ 8-Hydroxyapigenin / 4',5,7,8-Tetrahydroxyflavone / 5,7,8-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
No. 71 | No. 15 |
|
||||
|
C00036439
|
1-Hydroxypinoresinol 1-glucoside
/ 1-Hydroxypinoresinol 1-O-beta-D-glucoside |
CHEMBL517863
|
No. 174 | No. 22 |
|
|||
|
C00029633
|
Ursolic acid
/ Acetylursolic acid |
CHEMBL55086
CHEMBL410525 |
4 / 2 / 2 | No. 177 |
|
|||
|
C00036578
|
4-Hydroxyacetophenone 4-O-(6'-O-beta-D-apiofuranosyl)-beta-D-glucopyranoside
|
No. 267 |
|
|||||
|
C00036880
|
Carnosic acid
|
CHEMBL484853
CHEMBL1397655 |
C018381
|
17 / 23 / 55 | 6 / 4 | No. 323 | No. 41 |
|
|
C00029387
|
12-O-methylcarnosic acid
/ 12-O-Methyl carnosic acid / (+)-12-O-Methyl carnosic acid / Carnosic acid 12-methyl ether |
CHEMBL1096627
|
No. 323 | No. 41 |
|
|||
|
C00000805
|
alpha-Pinene
|
CHEMBL442565
|
C005451
|
3 / 3 / 2 | 0 / 1 | No. 476 | No. 35 |
|
|
C00000806
|
(-)-Nopinene
/ (-)-beta-Pinene |
CHEMBL501351
|
No. 476 | No. 35 |
|
|||
|
C00024161
|
Salvianolic acid K
|
No. 494 |
|
|||||
|
C00037781
|
Salvianolic acid I
|
No. 494 |
|
|||||
|
C00039745
|
Melitric acid A
|
No. 494 |
|
|||||
|
C00037766
|
Sagecoumarin
|
No. 494 |
|
|||||
|
C00039758
|
Methyl melitrate A
|
No. 494 |
|
|||||
|
C00037344
|
Isorosmanol
|
CHEMBL494659
CHEMBL2333536 |
No. 734 | No. 40 |
|
|||
|
C00030193
|
Epirosmanol
|
CHEMBL507166
|
No. 734 | No. 40 |
|
|||
|
C00031191
|
Rosmanol
|
No. 734 | No. 40 |
|
||||
|
C00003410
|
Carnosol
|
CHEMBL218693
CHEMBL1514916 |
C068623
|
17 / 17 / 17 | 12 / 0 | No. 734 | No. 40 |
|
|
C00031190
|
Rosmadial
/ (-)-Rosmadial |
CHEMBL494864
|
No. 734 | No. 40 |
|
|||
|
C00002770
|
Rosmarinic acid
|
CHEMBL66966
CHEMBL324842 CHEMBL1315100 CHEMBL2111558 |
48 / 35 / 38 | No. 749 |
|
|||
|
C00036922
|
Columbaridione
|
No. 792 | No. 40 |
|
||||
|
C00000856
|
4-Hydroxybenzoic acid
/ p-Hydroxybenzoic acid |
CHEMBL441343
|
C038193
|
21 / 7 / 16 | 2 / 1 | No. 817 | No. 81 |
|
|
C00000823
|
Limonene
|
CHEMBL15799
CHEMBL449062 |
C008281
|
7 / 21 / 48 | 6 / 6 | No. 848 | No. 35 |
|
|
C00000803
|
(-)-Limonene
|
CHEMBL15799
CHEMBL449062 |
7 / 21 / 48 | No. 848 | No. 35 |
|
||
|
C00000615
|
Caffeic acid
|
CHEMBL145
CHEMBL1320034 |
68 / 64 / 63 | No. 904 | No. 6 |
|
||
|
C00000580
|
trans-p-Coumaric acid
/ trans-p-Hydroxycinnamic acid |
CHEMBL66879
CHEMBL2336752 |
23 / 13 / 18 | No. 904 | No. 6 |
|
||
|
C00002682
|
Vanillic acid
/ 3-Methoxy-4-hydroxybenzoic acid |
CHEMBL120568
|
D014641
|
5 / 3 / 3 | 5 / 0 | No. 1073 |
|
|
|
C00000804
|
(-)-3-Isothujone
/ (-)-alpha-Thujone |
CHEMBL1444078
|
2 / 3 / 2 | No. 1161 | No. 35 |
|
||
|
C00000836
|
cis-Thujone
/ (+)-Thujone / beta-Thujone |
CHEMBL1444078
|
2 / 3 / 2 | No. 1161 | No. 35 |
|
||
|
C00037780
|
Salvianolic acid L
/ (-)-Salvianolic acid L |
No. 1276 |
|
|||||
|
C00037767
|
Sagerinic acid
/ (+)-Sagerinic acid |
No. 1276 |
|
|||||
|
C00000831
|
(+)-trans-Sabinol
|
C052984
|
No. 1343 | No. 35 |
|
|||
|
C00000857
|
(+)-Sabinene
|
CHEMBL452687
|
No. 1343 | No. 35 |
|
|||
|
C00002743
|
Ferulic acid
/ 3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid |
CHEMBL32749
|
C004999
|
110 / 52 / 40 | 16 / 6 | No. 1366 | No. 6 |
|
|
C00000828
|
(+)-Sabinone
|
No. 1561 | No. 35 |
|
||||
|
C00000862
|
trans-beta-Ocimene
|
No. 1698 | No. 34 |
|
||||
|
C00000843
|
cis-beta-Ocimene
|
No. 1698 | No. 34 |
|
||||
|
C00000819
|
(+)-Camphor
|
CHEMBL504760
CHEMBL1316134 |
D002164
|
99 / 56 / 51 | 5 / 3 | No. 1921 | No. 35 |
|
|
C00000841
|
6-Oxocamphor
|
CHEMBL1999760
|
No. 1921 | No. 35 |
|
|||
|
C00000853
|
Myrcene
|
CHEMBL455491
|
C008574
|
3 / 3 / 3 | No. 2285 | No. 34 |
|
|
|
C00000818
|
(+)-Camphene
|
CHEMBL506889
CHEMBL510535 |
No. 2460 | No. 35 |
|
|||
|
C00037506
|
Miltirone
|
CHEMBL45830
|
C068880
|
6 / 1 / 0 | No. 3136 |
|
||
|
C00000846
|
Geranyl diphosphate
/ Geranyl pyrophosphate |
CHEMBL41342
|
C015234
|
1 / 0 / 0 | 2 / 0 | No. 3475 | No. 34 |
|
|
C00000832
|
(3R)-Linalyl diphosphate
|
No. 3475 | No. 34 |
|
||||
|
C00000861
|
Terpinolene
|
CHEMBL454697
|
C027009
|
1 / 0 | No. 3725 |
|
||
|
C00000830
|
cis-Sabinene hydrate
|
No. 3782 | No. 35 |
|
||||
|
C00000821
|
(+)-trans-Sabinene hydrate
|
No. 3782 | No. 35 |
|
||||
|
C00000837
|
2-Hydroxycampholonic acid
|
No. 5604 |
|
|||||
|
C00000840
|
alpha-Campholonic acid
|
No. 5604 |
|
|||||
|
C00000817
|
(+)-Bornyl diphosphate
/ (+)-Bornyl pyrophosphate |
C022082
|
No. 5842 | No. 35 |
|
|||
|
C00000834
|
1,2-Campholide
|
No. 6018 |
|
|||||
|
C00000847
|
Isoketocamphoric acid
|
No. 7078 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000580 C00000615 C00000674 C00000803 C00000819 C00000823 C00002743 C00002770 C00003817 C00003837 C00019064 | 0 / 3 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000615 C00000674 C00000819 C00000968 C00001050 C00002770 C00003817 C00003837 C00019420 C00036880 | 4 / 3 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000615 C00000674 C00000819 C00000968 C00002743 C00002770 C00003672 C00003817 C00036880 | 0 / 1 |
| P03372 | Estrogen receptor | NR3A1 | C00000580 C00000615 C00000674 C00000819 C00002682 C00002743 C00003672 C00003817 C00019420 | 1 / 1 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000615 C00000674 C00002743 C00002770 C00003817 C00003837 C00006229 C00019420 C00036880 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000615 C00000674 C00000804 C00000805 C00000836 C00000853 C00000968 C00003672 C00003817 | 3 / 2 |
| P06746 | DNA polymerase beta | Enzyme | C00000615 C00000674 C00001050 C00002770 C00003672 C00003837 C00019064 C00023774 C00029633 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000615 C00000674 C00000819 C00000968 C00002743 C00002770 C00003672 C00003817 | 1 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00000615 C00000674 C00001050 C00002770 C00003817 C00006229 C00019064 C00029633 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000804 C00000836 C00000968 C00001017 C00002707 C00002770 C00003410 C00019064 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000615 C00000674 C00000819 C00000968 C00002743 C00002770 C00003672 C00003817 | 0 / 1 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00000615 C00000674 C00000819 C00002743 C00002770 C00003817 C00003837 C00019064 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000615 C00000674 C00000819 C00000968 C00002743 C00002770 C00003672 C00003817 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00000674 C00000819 C00000968 C00001050 C00002770 C00003817 C00003837 C00019064 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000615 C00000674 C00000819 C00000968 C00002743 C00002770 C00003672 C00003817 | 1 / 1 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000615 C00000674 C00000968 C00002770 C00003817 C00019420 C00036880 | 2 / 2 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00000674 C00000819 C00001043 C00002743 C00002770 C00003817 C00019420 | 0 / 1 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000615 C00000805 C00000819 C00000968 C00002743 C00003817 C00036880 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00000615 C00000674 C00001050 C00002770 C00003672 C00003817 C00036880 | 1 / 1 |
| O00255 | Menin | Unclassified protein | C00000615 C00000674 C00000819 C00001050 C00003410 C00003817 C00036880 | 2 / 5 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00000674 C00000803 C00000823 C00000968 C00001050 C00003817 C00036880 | 7 / 37 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000615 C00000674 C00000819 C00001050 C00003410 C00003817 C00036880 | 1 / 2 |
| O75496 | Geminin | Unclassified protein | C00000674 C00000968 C00002707 C00002743 C00003410 C00003817 C00019064 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000674 C00000968 C00002682 C00002770 C00003817 C00003837 C00019064 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00000615 C00000674 C00000819 C00000968 C00003817 C00019420 C00036880 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00000615 C00000674 C00001017 C00001050 C00002770 C00003817 C00019420 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000615 C00000674 C00000968 C00002770 C00003817 C00036880 | 3 / 3 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000580 C00000615 C00000819 C00000856 C00002743 C00003817 | 1 / 8 |
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00000674 C00000968 C00001033 C00001043 C00003817 C00003834 | 0 / 0 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00000819 C00001016 C00001050 C00002743 C00003817 C00003837 | 0 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00000674 C00000819 C00000968 C00002743 C00003817 C00037506 | 1 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000615 C00000674 C00002770 C00003410 C00006229 C00036880 | 0 / 0 |
| P04062 | Glucosylceramidase | Enzyme | C00000674 C00001050 C00002770 C00003817 C00003837 C00006229 | 6 / 4 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00000615 C00000674 C00000803 C00000823 C00002770 C00003817 | 3 / 1 |
| P02545 | Prelamin-A/C | Unclassified protein | C00000615 C00000674 C00000803 C00000819 C00000823 C00003817 | 11 / 10 |
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00000674 C00000968 C00001033 C00001043 C00003817 C00003834 | 4 / 4 |
| P15121 | Aldose reductase | Enzyme | C00000580 C00000615 C00002682 C00002770 C00019064 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00000674 C00001017 C00002770 C00003817 C00019420 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00000674 C00000819 C00000853 C00002743 C00003817 | 0 / 1 |
| P14679 | Tyrosinase | Oxidoreductase | C00000580 C00000615 C00000674 C00002743 C00003672 | 4 / 2 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00000580 C00000615 C00000819 C00000856 C00002743 | 1 / 2 |
| P03956 | Interstitial collagenase | M10A | C00000615 C00000674 C00000819 C00002743 C00002770 | 0 / 1 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00002770 C00003817 C00019064 C00036880 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00000674 C00000968 C00001017 C00003817 | 4 / 1 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00000803 C00000823 C00000968 C00003817 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00000615 C00000674 C00000819 C00002743 | 2 / 2 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00000819 C00000853 C00003817 C00019064 | 0 / 0 |
| P04745 | Alpha-amylase 1 | Enzyme | C00000674 C00000968 C00001043 C00003834 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00000580 C00000615 C00000856 C00002743 | 0 / 1 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00000674 C00000968 C00001017 C00003817 | 2 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00000674 C00000968 C00003410 C00003817 | 1 / 1 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00000580 C00000615 C00000856 C00002743 | 0 / 0 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00000580 C00000615 C00000856 C00002743 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00000674 C00002770 C00003817 C00003837 | 1 / 1 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00000615 C00000674 C00002770 C00003837 | 0 / 0 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00000580 C00000615 C00000856 C00002743 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00000615 C00000674 C00002770 C00006229 | 1 / 1 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00000674 C00003672 C00003817 C00019064 | 0 / 0 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00000580 C00000615 C00000856 C00002743 | 0 / 0 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000615 C00003672 C00019064 C00037506 | 0 / 0 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00000615 C00000674 C00002743 C00003817 | 1 / 1 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00000580 C00000615 C00000856 C00002743 | 1 / 1 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00000580 C00000615 C00000856 C00002743 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00000819 C00002743 C00003817 C00019420 | 0 / 1 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00000819 C00000968 C00002743 C00003817 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000674 C00000803 C00000823 C00003817 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00000674 C00002770 C00003817 C00019064 | 0 / 1 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00000674 C00000819 C00002743 C00003817 | 1 / 1 |
| P39748 | Flap endonuclease 1 | Enzyme | C00000674 C00002770 C00003410 C00003817 | 0 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00000615 C00000674 C00000968 C00003817 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00000580 C00000615 C00000856 C00002743 | 1 / 2 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00000674 C00002770 C00003817 C00019064 | 1 / 4 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00000580 C00000615 C00000856 C00002743 | 0 / 0 |
| Q9Y3R4 | Sialidase-2 | Enzyme | C00000674 C00001043 C00003817 C00003834 | 0 / 0 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00000580 C00000615 C00000856 C00002743 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00000819 C00000968 C00002743 C00003817 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00000615 C00000674 C00002770 C00003817 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00000819 C00000968 C00002743 C00003817 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00003410 C00003817 C00019420 C00036880 | 2 / 3 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00000674 C00003749 C00003817 C00023774 | 0 / 0 |
| Q13093 | Platelet-activating factor acetylhydrolase | Enzyme | C00000580 C00000615 C00002743 C00002770 | 3 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00000615 C00000674 C00002770 C00003410 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00000674 C00000968 C00003817 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00000819 C00002743 C00003817 | 0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00000819 C00002743 C00002770 | 0 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00000819 C00002743 C00003817 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00000674 C00003817 C00019420 | 0 / 0 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00000805 C00000819 C00003817 | 0 / 0 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00000968 C00001050 C00003817 | 1 / 1 |
| P08246 | Neutrophil elastase | S1A | C00000819 C00002743 C00019420 | 2 / 1 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00000615 C00000819 C00002743 | 2 / 2 |
| P17252 | Protein kinase C alpha type | Alpha | C00000819 C00002743 C00003817 | 0 / 0 |
| P06280 | Alpha-galactosidase A | Enzyme | C00000615 C00000674 C00019420 | 1 / 1 |
| P14618 | Pyruvate kinase PKM | Enzyme | C00000968 C00002770 C00003817 | 0 / 0 |
| O60218 | Aldo-keto reductase family 1 member B10 | Enzyme | C00000580 C00000615 C00019064 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00003410 C00003672 C00003817 | 2 / 0 |
| P47869 | Gamma-aminobutyric acid receptor subunit alpha-2 | GABA-A alpha | C00001050 C00003817 C00003834 | 1 / 0 |
| Q16445 | Gamma-aminobutyric acid receptor subunit alpha-6 | GABA-A alpha | C00001050 C00003817 C00003834 | 0 / 0 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00003817 C00019064 C00029633 | 2 / 2 |
| P08183 | Multidrug resistance protein 1 | drug | C00000674 C00003672 C00003817 | 1 / 0 |
| Q12794 | Hyaluronidase-1 | Enzyme | C00000615 C00002743 C00002770 | 1 / 2 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00000674 C00002770 C00029633 | 0 / 0 |
| Q9UN88 | Gamma-aminobutyric acid receptor subunit theta | GABA-A theta | C00001050 C00003817 C00003834 | 0 / 0 |
| P28472 | Gamma-aminobutyric acid receptor subunit beta-3 | GABA-A beta | C00001050 C00003817 C00003834 | 1 / 0 |
| P14867 | Gamma-aminobutyric acid receptor subunit alpha-1 | GABA-A alpha | C00001050 C00003817 C00003834 | 1 / 1 |
| P48169 | Gamma-aminobutyric acid receptor subunit alpha-4 | GABA-A alpha | C00001050 C00003817 C00003834 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00000819 C00002743 C00019420 | 0 / 0 |
| O14764 | Gamma-aminobutyric acid receptor subunit delta | GABA-A delta | C00001050 C00003817 C00003834 | 1 / 1 |
| P31644 | Gamma-aminobutyric acid receptor subunit alpha-5 | GABA-A alpha | C00001050 C00003817 C00003834 | 0 / 0 |
| P18505 | Gamma-aminobutyric acid receptor subunit beta-1 | GABA-A beta | C00001050 C00003817 C00003834 | 0 / 0 |
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | C00000803 C00000823 C00003817 | 0 / 0 |
| Q99928 | Gamma-aminobutyric acid receptor subunit gamma-3 | GABA-A gamma | C00001050 C00003817 C00003834 | 0 / 0 |
| P78334 | Gamma-aminobutyric acid receptor subunit epsilon | GABA-A epsilon | C00001050 C00003817 C00003834 | 0 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00000674 C00000968 C00003817 | 4 / 2 |
| Q8N1C3 | Gamma-aminobutyric acid receptor subunit gamma-1 | GABA-A gamma | C00001050 C00003817 C00003834 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000674 C00003410 C00003817 | 2 / 0 |
| P34903 | Gamma-aminobutyric acid receptor subunit alpha-3 | GABA-A alpha | C00001050 C00003817 C00003834 | 0 / 0 |
| P18507 | Gamma-aminobutyric acid receptor subunit gamma-2 | GABA-A gamma | C00001050 C00003817 C00003834 | 4 / 2 |
| O00591 | Gamma-aminobutyric acid receptor subunit pi | GABA-A pi | C00001050 C00003817 C00003834 | 0 / 0 |
| P36888 | Receptor-type tyrosine-protein kinase FLT3 | Pdgfr | C00000674 C00003817 C00003834 | 1 / 1 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00002770 C00003410 C00019064 | 0 / 0 |
| P47870 | Gamma-aminobutyric acid receptor subunit beta-2 | GABA-A beta | C00001050 C00003817 C00003834 | 0 / 0 |
| Q8TDS4 | Hydroxycarboxylic acid receptor 2 | Hydroxycarboxylic acid receptor | C00000580 C00000615 C00002743 | 0 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00000968 C00003817 | 5 / 3 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00000819 C00002743 | 0 / 0 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00000819 C00002743 | 0 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00000819 C00002743 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00000819 C00002743 | 1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00000819 C00002743 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00000819 C00002743 | 0 / 0 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00000819 C00002743 | 0 / 1 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00000968 C00001050 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00000819 C00002743 | 1 / 0 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00000819 C00002743 | 0 / 0 |
| P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00002743 C00003817 | 0 / 0 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00000819 C00002743 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00000819 C00002743 | 0 / 0 |
| P16233 | Pancreatic triacylglycerol lipase | Hydrolase | C00003410 C00036880 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00000819 C00002743 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00000819 C00002743 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00000819 C00002743 | 1 / 0 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00000674 C00036880 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00000819 C00002743 | 1 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00000819 C00002743 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00000819 C00002743 | 0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00000819 C00002743 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00000819 C00002743 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00000819 C00002743 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00000819 C00002743 | 1 / 0 |
| P34969 | 5-hydroxytryptamine receptor 7 | Serotonin receptor | C00002743 C00023774 | 0 / 0 |
| P08047 | Transcription factor Sp1 | Unclassified protein | C00003672 C00003749 | 0 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00000819 C00002743 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00000819 C00002743 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00000819 C00002743 | 0 / 0 |
| Q00534 | Cyclin-dependent kinase 6 | CMGC serine/threonine protein kinase family | C00000674 C00003817 | 1 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00000819 C00002743 | 1 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00000819 C00002743 | 0 / 0 |
| P09874 | Poly [ADP-ribose] polymerase 1 | Enzyme | C00000674 C00003817 | 0 / 0 |
| P11309 | Serine/threonine-protein kinase pim-1 | Pim | C00000674 C00003817 | 0 / 0 |
| P14061 | Estradiol 17-beta-dehydrogenase 1 | Enzyme | C00000968 C00003817 | 0 / 0 |
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00002743 C00003817 | 3 / 0 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00000819 C00002743 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00003837 C00006229 | 7 / 3 |
| O95271 | Tankyrase-1 | Enzyme | C00000674 C00003817 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00000968 C00003817 | 1 / 0 |
| P17516 | Aldo-keto reductase family 1 member C4 | Enzyme | C00000580 C00000615 | 1 / 0 |
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00000674 C00003817 | 0 / 0 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00000819 C00002743 | 2 / 0 |
| Q9NPH5 | NADPH oxidase 4 | Enzyme | C00000674 C00003817 | 0 / 0 |
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00000856 C00003817 | 0 / 0 |
| P51452 | Dual specificity protein phosphatase 3 | Ser_Thr_Tyr | C00000615 C00019064 | 0 / 0 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00000819 C00002743 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00000819 C00002743 | 0 / 0 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00000674 C00003749 | 0 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00000674 C00002770 | 1 / 0 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00000819 C00002743 | 0 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00000819 C00002743 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00000819 C00002743 | 2 / 0 |
| O95067 | G2/mitotic-specific cyclin-B2 | Other cytosolic protein | C00000674 C00003817 | 0 / 0 |
| P14635 | G2/mitotic-specific cyclin-B1 | Other cytosolic protein | C00000674 C00003817 | 0 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00000819 C00002743 | 1 / 1 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00000819 C00002743 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00000819 C00002743 | 1 / 0 |
| Q13315 | Serine-protein kinase ATM | Atypical serine/threonine protein kinase PIKK subfamily | C00000968 C00001050 | 1 / 4 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00000819 C00002743 | 0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00000819 C00002743 | 0 / 0 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00000968 C00003817 | 0 / 0 |
| P06276 | Cholinesterase | Hydrolase | C00000674 C00003817 | 0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00000819 C00002743 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00000819 C00002743 | 3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00000819 C00002743 | 0 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00000674 C00002770 | 1 / 2 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00000819 C00002743 | 0 / 0 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00000819 C00002743 | 0 / 0 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00000819 C00002743 | 1 / 1 |
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00000674 C00036880 | 2 / 0 |
| P42330 | Aldo-keto reductase family 1 member C3 | Enzyme | C00000580 C00000615 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00000674 C00003817 | 3 / 4 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00002743 C00003817 | 5 / 1 |
| P35236 | Tyrosine-protein phosphatase non-receptor type 7 | Tyr | C00000615 C00019064 | 0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00000819 C00002743 | 1 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00000819 C00002743 | 0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00000819 C00002743 | 2 / 1 |
| P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | C00000674 C00003817 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00000819 C00002743 | 0 / 0 |
| P06493 | Cyclin-dependent kinase 1 | Cdc2 | C00000674 C00003817 | 0 / 0 |
| P08253 | 72 kDa type IV collagenase | M10A | C00000615 C00000674 | 1 / 3 |
| P52895 | Aldo-keto reductase family 1 member C2 | Enzyme | C00000580 C00000615 | 1 / 0 |
| P29466 | Caspase-1 | C14 | C00000819 C00002743 | 0 / 0 |
| Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | Tyr | C00000615 C00019064 | 4 / 2 |
| Q15046 | Lysine--tRNA ligase | Enzyme | C00000674 C00003817 | 2 / 1 |
| Q15078 | Cyclin-dependent kinase 5 activator 1 | REG serine/threonine protein kinase family | C00000674 C00003817 | 0 / 0 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00000819 C00002743 | 0 / 0 |
| Q04828 | Aldo-keto reductase family 1 member C1 | Enzyme | C00000580 C00000615 | 0 / 0 |
| Q00535 | Cyclin-dependent kinase 5 | Cdk5 | C00000674 C00003817 | 0 / 0 |
| Q8WWL7 | G2/mitotic-specific cyclin-B3 | Other cytosolic protein | C00000674 C00003817 | 0 / 0 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00000615 C00003817 | 5 / 2 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00000819 C00002743 | 0 / 0 |
| P37059 | Estradiol 17-beta-dehydrogenase 2 | Enzyme | C00000968 C00003817 | 0 / 0 |
| Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00000856 C00003817 | 0 / 0 |
| P51580 | Thiopurine S-methyltransferase | Enzyme | C00000856 C00002682 | 1 / 1 |
| Q9H2K2 | Tankyrase-2 | Enzyme | C00000674 C00003817 | 0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00000819 C00002743 | 0 / 0 |
| P49840 | Glycogen synthase kinase-3 alpha | Gsk | C00000674 C00003817 | 0 / 0 |
| Q02880 | DNA topoisomerase 2-beta | Isomerase | C00003817 C00023774 | 0 / 0 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00000819 C00002743 | 1 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00000615 C00003817 | 0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00000819 C00002743 | 0 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00000819 C00002743 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00000819 C00002743 | 0 / 0 |
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00000674 C00003817 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00000819 C00002743 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00000819 C00002743 | 0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00000819 C00002743 | 0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00000819 C00002743 | 0 / 0 |
| Q9UQ49 | Sialidase-3 | Enzyme | C00000856 | 0 / 0 |
| O75116 | Rho-associated protein kinase 2 | Rock | C00003817 | 0 / 0 |
| P09884 | DNA polymerase alpha catalytic subunit | Transferase | C00023774 | 0 / 0 |
| P30305 | M-phase inducer phosphatase 2 | Ser_Thr_Tyr | C00037506 | 0 / 0 |
| P07948 | Tyrosine-protein kinase Lyn | Src | C00003817 | 0 / 0 |
| O15530 | 3-phosphoinositide-dependent protein kinase 1 | Pdk1 | C00003817 | 0 / 0 |
| O14763 | Tumor necrosis factor receptor superfamily member 10B | Unclassified protein | C00000674 | 1 / 0 |
| P35228 | Nitric oxide synthase, inducible | Enzyme | C00019064 | 1 / 1 |
| P31749 | RAC-alpha serine/threonine-protein kinase | Akt | C00003817 | 4 / 1 |
| P02647 | Apolipoprotein A-I | Unclassified protein | C00000968 | 3 / 2 |
| O00141 | Serine/threonine-protein kinase Sgk1 | AGC serine/threonine protein kinase SGK subfamily | C00003817 | 0 / 0 |
| Q15759 | Mitogen-activated protein kinase 11 | p38 | C00003817 | 0 / 0 |
| P41240 | Tyrosine-protein kinase CSK | Csk | C00003817 | 0 / 0 |
| O00748 | Cocaine esterase | Enzyme | C00037506 | 0 / 0 |
| O75762 | Transient receptor potential cation channel subfamily A member 1 | Unclassified protein | C00000819 | 1 / 0 |
| P51692 | Signal transducer and activator of transcription 5B | Unclassified protein | C00002770 | 1 / 1 |
| Q92887 | Canalicular multispecific organic anion transporter 1 | Unclassified protein | C00003817 | 1 / 1 |
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00003817 | 1 / 0 |
| Q9Y4K4 | Mitogen-activated protein kinase kinase kinase kinase 5 | STE serine/threonine protein kinase KHS subfamily | C00003817 | 0 / 0 |
| P56817 | Beta-secretase 1 | A1A | C00003817 | 0 / 0 |
| P39900 | Macrophage metalloelastase | M10A | C00000674 | 0 / 0 |
| P18433 | Receptor-type tyrosine-protein phosphatase alpha | Receptor tyrosine-protein phosphatase | C00019064 | 0 / 0 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00000615 | 0 / 0 |
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00003817 | 0 / 0 |
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00000856 | 0 / 0 |
| P00747 | Plasminogen | S1A | C00003865 | 1 / 2 |
| O43451 | Maltase-glucoamylase, intestinal | Hydrolase | C00019420 | 0 / 0 |
| Q13133 | Oxysterols receptor LXR-alpha | NR1H3 | C00000968 | 0 / 0 |
| P49137 | MAP kinase-activated protein kinase 2 | CAMK serine/threonine protein kinase MAPKAPK | C00003817 | 0 / 0 |
| P45452 | Collagenase 3 | M10A | C00000674 | 1 / 1 |
| O14757 | Serine/threonine-protein kinase Chk1 | Chk1 | C00003817 | 0 / 0 |
| P12931 | Proto-oncogene tyrosine-protein kinase Src | Src | C00002770 | 0 / 0 |
| P30304 | M-phase inducer phosphatase 1 | Ser_Thr_Tyr | C00037506 | 0 / 0 |
| Q9H244 | P2Y purinoceptor 12 | Purine receptor | C00019420 | 1 / 1 |
| P80404 | 4-aminobutyrate aminotransferase, mitochondrial | Transferase | C00000856 | 1 / 1 |
| Q8IW41 | MAP kinase-activated protein kinase 5 | CAMK serine/threonine protein kinase MAPKAPK | C00003817 | 0 / 0 |
| P17706 | Tyrosine-protein phosphatase non-receptor type 2 | Tyr | C00019064 | 0 / 1 |
| Q04760 | Lactoylglutathione lyase | Enzyme | C00000674 | 0 / 0 |
| P54646 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | Ampk | C00003817 | 0 / 0 |
| P35869 | Aryl hydrocarbon receptor | Transcription Factor | C00003817 | 0 / 0 |
| P28907 | ADP-ribosyl cyclase 1 | Enzyme | C00000674 | 0 / 1 |
| P43405 | Tyrosine-protein kinase SYK | Syk | C00003817 | 0 / 0 |
| P08254 | Stromelysin-1 | M10A | C00000674 | 1 / 0 |
| P29350 | Tyrosine-protein phosphatase non-receptor type 6 | Tyr | C00019064 | 0 / 0 |
| P23141 | Liver carboxylesterase 1 | Enzyme | C00037506 | 0 / 0 |
| Q13627 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | CMGC dual-specificity kinase DYRK1 | C00003817 | 1 / 0 |
| P04054 | Phospholipase A2 | Enzyme | C00019064 | 0 / 0 |
| P14324 | Farnesyl pyrophosphate synthase | Transferase | C00000846 | 0 / 0 |
| P53778 | Mitogen-activated protein kinase 12 | p38 | C00003817 | 0 / 0 |
| P80365 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Enzyme | C00003672 | 1 / 1 |
| P24666 | Low molecular weight phosphotyrosine protein phosphatase | Tyr | C00019064 | 0 / 0 |
| P23469 | Receptor-type tyrosine-protein phosphatase epsilon | Receptor tyrosine-protein phosphatase | C00019064 | 0 / 0 |
| P37173 | TGF-beta receptor type-2 | TKL dual-specificity kinase STKR type 2 subfamily | C00000968 | 4 / 3 |
| P00734 | Prothrombin | S1A | C00003672 | 4 / 2 |
| P24298 | Alanine aminotransferase 1 | Enzyme | C00000615 | 0 / 0 |
| P51843 | Nuclear receptor subfamily 0 group B member 1 | Nuclear hormone receptor subfamily 0 group B member 1 | C00001050 | 2 / 2 |
| Q9Y5X4 | Photoreceptor-specific nuclear receptor | NR2E3 | C00003410 | 2 / 2 |
| P40225 | Thrombopoietin | Unclassified protein | C00003817 | 1 / 1 |
| O00167 | Eyes absent homolog 2 | Enzyme | C00002707 | 0 / 0 |
| P42224 | Signal transducer and activator of transcription 1-alpha/beta | Unclassified protein | C00002770 | 3 / 3 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00003410 | 0 / 0 |
| Q8NET8 | Transient receptor potential cation channel subfamily V member 3 | Unclassified protein | C00000819 | 1 / 0 |
| Q8TDU6 | G-protein coupled bile acid receptor 1 | Steroid-like ligand receptor | C00019064 | 0 / 0 |
| Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Other cytosolic protein | C00002770 | 0 / 0 |
| P55789 | FAD-linked sulfhydryl oxidase ALR | Enzyme | C00001050 | 1 / 0 |
| P33527 | Multidrug resistance-associated protein 1 | drugs | C00003817 | 0 / 0 |
| Q12791 | Calcium-activated potassium channel subunit alpha-1 | KCNM, KCa1.x | C00003817 | 1 / 1 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00003837 | 0 / 0 |
| P40763 | Signal transducer and activator of transcription 3 | Transcription Factor | C00002770 | 1 / 2 |
| O15264 | Mitogen-activated protein kinase 13 | p38 | C00003817 | 0 / 0 |
| Q15418 | Ribosomal protein S6 kinase alpha-1 | Rskb | C00003817 | 0 / 0 |
| P37840 | Alpha-synuclein | Unclassified protein | C00003410 | 4 / 2 |
| P10145 | Interleukin-8 | Secreted protein | C00003817 | 0 / 0 |
| P51649 | Succinate-semialdehyde dehydrogenase, mitochondrial | Oxidoreductase | C00000856 | 1 / 1 |
| P68400 | Casein kinase II subunit alpha | Ck2 | C00003817 | 0 / 0 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00000856 | 0 / 0 |
| P42858 | Huntingtin | Unclassified protein | C00002682 | 1 / 1 |
| P11413 | Glucose-6-phosphate 1-dehydrogenase | Enzyme | C00003410 | 1 / 2 |
| P09769 | Tyrosine-protein kinase Fgr | Src | C00003817 | 0 / 0 |
| P68871 | Hemoglobin subunit beta | Secreted protein | C00003817 | 4 / 4 |
| O75582 | Ribosomal protein S6 kinase alpha-5 | CAMK serine/threonine protein kinase MSKB subfamily | C00003817 | 0 / 0 |
| P49327 | Fatty acid synthase | Transferase | C00000674 | 0 / 0 |
| Q9HAW7 | UDP-glucuronosyltransferase 1-7 | Enzyme | C00000856 | 0 / 0 |
| P45983 | Mitogen-activated protein kinase 8 | Jnk | C00003817 | 0 / 0 |
| P53779 | Mitogen-activated protein kinase 10 | Jnk | C00003817 | 0 / 1 |
| P45984 | Mitogen-activated protein kinase 9 | Jnk | C00003817 | 0 / 0 |
| Q9HC97 | G-protein coupled receptor 35 | Kynurenic acid receptor | C00000674 | 0 / 0 |
| P51570 | Galactokinase | Enzyme | C00000674 | 1 / 1 |
| Q9GZT9 | Egl nine homolog 1 | Enzyme | C00000615 | 1 / 1 |
| P23443 | Ribosomal protein S6 kinase beta-1 | p70 | C00003817 | 0 / 0 |
| P22694 | cAMP-dependent protein kinase catalytic subunit beta | Pka | C00003817 | 0 / 0 |
| P17612 | cAMP-dependent protein kinase catalytic subunit alpha | Pka | C00003817 | 0 / 0 |
| P22612 | cAMP-dependent protein kinase catalytic subunit gamma | Pka | C00003817 | 0 / 0 |
| P07900 | Heat shock protein HSP 90-alpha | Other cytosolic protein | C00000615 | 0 / 0 |
| P08238 | Heat shock protein HSP 90-beta | Other cytosolic protein | C00000615 | 0 / 0 |
| P10586 | Receptor-type tyrosine-protein phosphatase F | Receptor tyrosine-protein phosphatase | C00019064 | 0 / 0 |
| P09619 | Platelet-derived growth factor receptor beta | Pdgfr | C00019420 | 5 / 1 |
| P16234 | Platelet-derived growth factor receptor alpha | Pdgfr | C00019420 | 2 / 1 |
| Q9HCP0 | Casein kinase I isoform gamma-1 | Ck1 | C00003817 | 0 / 0 |
| P48730 | Casein kinase I isoform delta | Ck1 | C00003817 | 1 / 0 |
| P49674 | Casein kinase I isoform epsilon | Ck1 | C00003817 | 0 / 0 |
| P78368 | Casein kinase I isoform gamma-2 | Ck1 | C00003817 | 0 / 0 |
| P48729 | Casein kinase I isoform alpha | Ck1 | C00003817 | 0 / 0 |
| Q02750 | Dual specificity mitogen-activated protein kinase kinase 1 | Ste7 | C00003817 | 1 / 1 |
| Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00002770 | 0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00000674 | 2 / 1 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00000674
C00000823
C00000968
C00001033
C00001043 C00002743 C00003410 C00003817 C00003834 |
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00000674
C00001033
C00001043
C00003410
C00003817 C00003834 |
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00001043
C00002743
C00003817
C00003834
C00019064 |
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00000674
C00002743
C00003817
C00019064
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00000674
C00000968
C00002743
C00003817
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00000674
C00002743
C00003817
C00019064
|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00000674
C00000968
C00003410
C00003817
|
| 847 | CAT | catalase (EC:1.11.1.6) |
C00000674
C00000968
C00003817
C00019064
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00000674
C00000968
C00003817
C00019064
|
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00000674
C00003410
C00003817
C00019064
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00000674
C00000823
C00000968
C00003817
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00000674
C00003410
C00003817
C00019064
|
| 54659 | UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C | UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) |
C00000674
C00002682
C00002743
|
| 54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) |
C00002682
C00002743
C00003817
|
| 54577 | UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G | UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) |
C00002682
C00002743
C00003817
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00000674
C00003410
C00003817
|
| 7412 | VCAM1, CD106, INCAM-100 | vascular cell adhesion molecule 1 |
C00000674
C00003817
C00019064
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00000674
C00003410
C00003817
|
| 6401 | SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2 | selectin E |
C00000674
C00003817
C00019064
|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00000674
C00000861
C00003817
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00000823
C00000968
C00003817
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00000674
C00000968
C00019420
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00000674
C00003817
C00019064
|
| 841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00000674
C00003817
C00019064
|
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00000674
C00000968
C00003817
|
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00000968
C00002743
C00019064
|
| 54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) |
C00002682
C00002743
C00003817
|
| 8626 | TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L | tumor protein p63 |
C00000674
C00003817
|
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00000674
C00003817
|
| 5728 | PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1 | phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) |
C00003749
C00019064
|
| 1017 | CDK2, p33(CDK2) | cyclin-dependent kinase 2 (EC:2.7.11.22) |
C00000674
C00000968
|
| 3725 | JUN, AP-1, AP1, c-Jun | jun proto-oncogene |
C00000674
C00003817
|
| 1027 | CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
C00000674
C00000968
|
| 54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00000968
C00003817
|
| 1588 | CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM | cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00000968
C00003817
|
| 7402 | UTRN, DMDL, DRP, DRP1 | utrophin |
C00000968
C00003817
|
| 4793 | NFKBIB, IKBB, TRIP9 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
C00000674
C00003817
|
| 3565 | IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4 | interleukin 4 |
C00000674
C00003817
|
| 2353 | FOS, AP-1, C-FOS, p55 | FBJ murine osteosarcoma viral oncogene homolog |
C00000674
C00003817
|
| 2203 | FBP1, FBP | fructose-1,6-bisphosphatase 1 (EC:3.1.3.11) |
C00000674
C00003817
|
| 2100 | ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 | estrogen receptor 2 (ER beta) |
C00000674
C00003817
|
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00000674
C00003817
|
| 1031 | CDKN2C, INK4C, p18, p18-INK4C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
C00000674
C00003817
|
| 983 | CDK1, CDC2, CDC28A, P34CDC2 | cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) |
C00000674
C00003817
|
| 958 | CD40, Bp50, CDW40, TNFRSF5, p50 | CD40 molecule, TNF receptor superfamily member 5 |
C00000674
C00003817
|
| 8000 | PSCA, PRO232 | prostate stem cell antigen |
C00000674
C00003817
|
| 891 | CCNB1, CCNB | cyclin B1 |
C00000674
C00003817
|
| 6817 | SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) |
C00000856
C00003817
|
| 2729 | GCLC, GCL, GCS, GLCL, GLCLC | glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) |
C00003410
C00003817
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00000674
C00003817
|
| 9540 | TP53I3, PIG3 | tumor protein p53 inducible protein 3 |
C00000674
C00003817
|
| 840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) |
C00000674
C00003817
|
| 4780 | NFE2L2, NRF2 | nuclear factor, erythroid 2-like 2 |
C00003410
C00019064
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00000823
C00003410
|
| 4312 | MMP1, CLG, CLGN | matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) |
C00000674
C00003817
|
| 7161 | TP73, P73 | tumor protein p73 |
C00000674
C00003817
|
| 54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) |
C00000674
C00003817
|
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00000674
C00003817
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00000674
C00002743
|
| 8839 | WISP2, CCN5, CT58, CTGF-L | WNT1 inducible signaling pathway protein 2 |
C00000674
C00003817
|
| 177 | AGER, RAGE | advanced glycosylation end product-specific receptor |
C00000674
C00019064
|
| 23621 | BACE1, ASP2, BACE, HSPC104 | beta-site APP-cleaving enzyme 1 (EC:3.4.23.46) |
C00002743
|
| 2566 | GABRG2, CAE2, ECA2, GEFSP3 | gamma-aminobutyric acid (GABA) A receptor, gamma 2 |
C00000819
|
| 2561 | GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
C00000819
|
| 3065 | HDAC1, GON-10, HD1, RPD3, RPD3L1 | histone deacetylase 1 (EC:3.5.1.98) |
C00019064
|
| 3146 | HMGB1, HMG1, HMG3, SBP-1 | high mobility group box 1 |
C00019064
|
| 4233 | MET, AUTS9, HGFR, RCCP2, c-Met | met proto-oncogene (EC:2.7.10.1) |
C00019064
|
| 5052 | PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2 | peroxiredoxin 1 (EC:1.11.1.15) |
C00019064
|
| 2554 | GABRA1, ECA4, EJM, EJM5 | gamma-aminobutyric acid (GABA) A receptor, alpha 1 |
C00000819
|
| 7150 | TOP1, TOPI | topoisomerase (DNA) I (EC:5.99.1.2) |
C00019064
|
| 7153 | TOP2A, TOP2, TP2A | topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) |
C00019064
|
| 1555 | CYP2B6, CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450 | cytochrome P450, family 2, subfamily B, polypeptide 6 (EC:1.14.14.1) |
C00000819
|
| 10599 | SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6 | solute carrier organic anion transporter family, member 1B1 |
C00023774
|
| 4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) |
C00002682
|
| 405 | ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 | aryl hydrocarbon receptor nuclear translocator |
C00003817
|
| 330 | BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 | baculoviral IAP repeat containing 3 |
C00003817
|
| 3551 | IKBKB, IKK-beta, IKK2, IKKB, NFKBIKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) |
C00003410
|
| 2730 | GCLM, GLCLR | glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2) |
C00003410
|
| 3952 | LEP, LEPD, OB, OBS | leptin |
C00000856
|
| 7421 | VDR, NR1I1 | vitamin D (1,25- dihydroxyvitamin D3) receptor |
C00036880
|
| 6256 | RXRA, NR2B1 | retinoid X receptor, alpha |
C00036880
|
| 5914 | RARA, NR1B1, RAR | retinoic acid receptor, alpha |
C00036880
|
| 1080 | CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1 | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) |
C00003817
|
| 6387 | CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B | chemokine (C-X-C motif) ligand 12 |
C00003817
|
| 1584 | CYP11B1, CPN1, CYP11B, FHI, P450C11 | cytochrome P450, family 11, subfamily B, polypeptide 1 (EC:1.14.15.4) |
C00003817
|
| 1586 | CYP17A1, CPT7, CYP17, P450C17, S17AH | cytochrome P450, family 17, subfamily A, polypeptide 1 (EC:1.14.99.9 4.1.2.30) |
C00003817
|
| 1589 | CYP21A2, CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B | cytochrome P450, family 21, subfamily A, polypeptide 2 (EC:1.14.99.10) |
C00003817
|
| 1559 | CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 | cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00003817
|
| 2064 | ERBB2, CD340, HER-2, HER-2/neu, HER2, MLN_19, NEU, NGL, TKR1 | v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1) |
C00003817
|
| 5468 | PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma | peroxisome proliferator-activated receptor gamma |
C00036880
|
| 929 | CD14 | CD14 molecule |
C00036880
|
| 100136148 |
C00036880
|
||
| 5906 | RAP1A, KREV-1, KREV1, RAP1, SMGP21 | RAP1A, member of RAS oncogene family |
C00000846
|
| 3091 | HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
C00003817
|
| 3284 | HSD3B2, HSD3B, HSDB, SDR11E2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (EC:1.1.1.145 5.3.3.1) |
C00003817
|
| 3156 | HMGCR, LDLCQ3 | 3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34) |
C00000846
|
| 1019 | CDK4, CMM3, PSK-J3 | cyclin-dependent kinase 4 (EC:2.7.11.22) |
C00000968
|
| 10057 | ABCC5, ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
C00000968
|
| 10257 | ABCC4, EST170205, MOAT-B, MOATB, MRP4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
C00000968
|
| 1499 | CTNNB1, CTNNB, MRD19, armadillo | catenin (cadherin-associated protein), beta 1, 88kDa |
C00003749
|
| 5241 | PGR, NR3C3, PR | progesterone receptor |
C00003817
|
| 5562 | PRKAA1, AMPK, AMPKa1 | protein kinase, AMP-activated, alpha 1 catalytic subunit (EC:2.7.11.1 2.7.11.26 2.7.11.27 2.7.11.31) |
C00003817
|
| 4852 | NPY, PYY4 | neuropeptide Y |
C00000823
|
| 6198 | RPS6KB1, PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70_S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha | ribosomal protein S6 kinase, 70kDa, polypeptide 1 (EC:2.7.11.1) |
C00003817
|
| 6783 | SULT1E1, EST, EST-1, ST1E1, STE | sulfotransferase family 1E, estrogen-preferring, member 1 (EC:2.8.2.4) |
C00003817
|
| 3265 | HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1 | Harvey rat sarcoma viral oncogene homolog |
C00000823
|
| 162514 | TRPV3, OLMS, VRL3 | transient receptor potential cation channel, subfamily V, member 3 |
C00000819
|
| 7299 | TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 | tyrosinase (EC:1.14.18.1) |
C00002743
|
| 6319 | SCD, FADS5, MSTP008, SCD1, SCDOS | stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1) |
C00002743
|
| 54600 | UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I | UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) |
C00003817
|
| 7366 | UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 | UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) |
C00003817
|
| 5925 | RB1, OSRC, RB, p105-Rb, pRb, pp110 | retinoblastoma 1 |
C00002743
|
| 5742 | PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00002743
|
| 9429 | ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1 | ATP-binding cassette, sub-family G (WHITE), member 2 |
C00000674
|
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 |
C00000674
|
| 329 | BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1 | baculoviral IAP repeat containing 2 |
C00000674
|
| 890 | CCNA2, CCN1, CCNA | cyclin A2 |
C00000674
|
| 972 | CD74, DHLAG, HLADG, II, Ia-GAMMA | CD74 molecule, major histocompatibility complex, class II invariant chain |
C00000674
|
| 1437 | CSF2, GMCSF | colony stimulating factor 2 (granulocyte-macrophage) |
C00000674
|
| 1577 | CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3 | cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1) |
C00000674
|
| 1950 | EGF, HOMG4, URG | epidermal growth factor |
C00000674
|
| 1956 | EGFR, ERBB, ERBB1, HER1, PIG61, mENA | epidermal growth factor receptor (EC:2.7.10.1) |
C00000674
|
| 1958 | EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225 | early growth response 1 |
C00000674
|
| 2354 | FOSB, AP-1, G0S3, GOS3, GOSB | FBJ murine osteosarcoma viral oncogene homolog B |
C00000674
|
| 4616 | GADD45B, GADD45BETA, MYD118 | growth arrest and DNA-damage-inducible, beta |
C00000674
|
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00000674
|
| 3726 | JUNB, AP-1 | jun B proto-oncogene |
C00000674
|
| 3727 | JUND, AP-1 | jun D proto-oncogene |
C00000674
|
| 5602 | MAPK10, JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK | mitogen-activated protein kinase 10 (EC:2.7.11.24) |
C00000674
|
| 5599 | MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c | mitogen-activated protein kinase 8 (EC:2.7.11.24) |
C00000674
|
| 5601 | MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK | mitogen-activated protein kinase 9 (EC:2.7.11.24) |
C00000674
|
| 4790 | NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
C00000674
|
| 9572 | NR1D1, EAR1, THRA1, THRAL, ear-1, hRev | nuclear receptor subfamily 1, group D, member 1 |
C00000674
|
| 5347 | PLK1, PLK, STPK13 | polo-like kinase 1 (EC:2.7.11.21) |
C00000674
|
| 5747 | PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK | protein tyrosine kinase 2 (EC:2.7.10.2) |
C00000674
|
| 2810 | SFN, YWHAS | stratifin |
C00000674
|
| 6647 | SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer | superoxide dismutase 1, soluble (EC:1.15.1.1) |
C00000674
|
| 29110 | TBK1, NAK, T2K | TANK-binding kinase 1 (EC:2.7.11.1) |
C00000674
|
| 7128 | TNFAIP3, A20, OTUD7C, TNFA1P2 | tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12) |
C00000674
|
| 8743 | TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL | tumor necrosis factor (ligand) superfamily, member 10 |
C00000674
|
| 10451 | VAV3 | vav 3 guanine nucleotide exchange factor |
C00000674
|
| 331 | XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 | X-linked inhibitor of apoptosis |
C00000674
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #300018 | 46,xy sex reversal 2; srxy2 |
P51843
|
| #614279 | 46,xy sex reversal 8; srxy8 |
P17516
P52895 |
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #300200 | Adrenal hypoplasia, congenital; ahc |
P51843
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #615224 | Advanced sleep phase syndrome, familial, 2; fasps2 |
P48730
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 P47869 |
| #105200 | Amyloidosis, familial visceral |
P02647
|
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #300908 | Anemia, nonspherocytic hemolytic, due to g6pd deficiency |
P11413
|
| #218030 | Apparent mineralocorticoid excess; ame |
P80365
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #600807 | Asthma, susceptibility to |
Q13093
|
| #608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
| #208900 | Ataxia-telangiectasia; at |
Q13315
|
| #209950 | Atypical mycobacteriosis, familial |
P42224
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #615007 | Basal ganglia calcification, idiopathic, 4; ibgc4 |
P09619
|
| #613985 | Beta-thalassemia |
P68871
|
| #603902 | Beta-thalassemia, dominant inclusion body type |
P68871
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #609821 | Bleeding disorder, platelet-type, 8; bdplt8 |
Q9H244
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| %606641 | Body mass index; bmi |
P37231
|
| #114480 | Breast cancer |
P31749
P38398 |
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #300615 | Brunner syndrome |
P21397
|
| #614162 | Candidiasis, familial, 7; candf7 |
P42224
|
| #615279 | Cardiofaciocutaneous syndrome 3; cfc3 |
Q02750
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #613641 | Charcot-marie-tooth disease, recessive intermediate b; cmtrib |
Q15046
|
| #614331 | Colorectal cancer, hereditary nonpolyposis, type 6; hnpcc6 |
P37173
|
| #114500 | Colorectal cancer; crc |
P18054
P31749 P84022 Q14191 |
| #614466 | Coronary heart disease, susceptibility to, 6; chds6 |
P08254
|
| #615109 | Cowden syndrome 6; cws6 |
P31749
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
P22310 |
| #606785 | Crigler-najjar syndrome, type ii |
P22309
P22310 |
| #162800 | Cyclic neutropenia |
P08246
|
| #613916 | Deafness, autosomal recessive 89; dfnb89 |
Q15046
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #607208 | Dravet syndrome |
P18507
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #237500 | Dubin-johnson syndrome; djs |
Q92887
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #268100 | Enhanced s-cone syndrome; escs |
Q9Y5X4
|
| #607681 | Epilepsy, childhood absence, susceptibility to, 2; eca2 |
P18507
|
| #612269 | Epilepsy, childhood absence, susceptibility to, 5; eca5 |
P28472
|
| #613060 | Epilepsy, idiopathic generalized, susceptibility to, 10; eig10 |
O14764
|
| #611136 | Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 |
P14867
|
| #615040 | Episodic pain syndrome, familial, 1; feps1 |
O75762
|
| #609820 | Erythrocytosis, familial, 3; ecyt3 |
Q9GZT9
|
| #133239 | Esophageal cancer |
P04637
P18054 P37173 |
| #615363 | Estrogen resistance; estrr |
P03372
|
| #301500 | Fabry disease |
P06280
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613163 | Gaba-transaminase deficiency |
P80404
|
| #230200 | Galactokinase deficiency |
P51570
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #606764 | Gastrointestinal stromal tumor; gist |
P16234
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #609446 | Generalized epilepsy and paroxysmal dyskinesia; gepd |
Q12791
|
| #604233 | Generalized epilepsy with febrile seizures plus, type 1; gefsp1 |
P18507
|
| #611277 | Generalized epilepsy with febrile seizures plus, type 3; gefsp3 |
P18507
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #143500 | Gilbert syndrome |
P22309
P22310 |
| #137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
| #231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
| #137760 | Glaucoma, primary open angle; poag |
Q16678
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P04626 P37231 |
| #232300 | Glycogen storage disease ii |
P10253
|
| #245590 | Growth hormone insensitivity with immunodeficiency |
P51692
|
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #140700 | Heinz body anemias |
P68871
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #143100 | Huntington disease; hd |
P42858
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #147060 | Hyper-ige recurrent infection syndrome, autosomal dominant |
P40763
|
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #607685 | Hypereosinophilic syndrome, idiopathic; hes |
P16234
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #604091 | Hypoalphalipoproteinemia, primary |
P02647
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #147050 | Ige responsiveness, atopic; iger |
Q13093
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #607785 | Juvenile myelomonocytic leukemia; jmml |
P09619
Q06124 |
| #151100 | Leopard syndrome 1 |
Q06124
|
| #601626 | Leukemia, acute myeloid; aml |
P09619
P36888 |
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #610168 | Loeys-dietz syndrome, type 1b; lds1b |
P37173
|
| #610380 | Loeys-dietz syndrome, type 2b; lds2b |
P37173
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 P04637 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #611162 | Malaria, susceptibility to |
P35228
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #614104 | Mental retardation, autosomal dominant 7; mrd7 |
Q13627
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #156250 | Metachondromatosis; metcds |
Q06124
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #601492 | Mucopolysaccharidosis, type ix; mps9 |
Q12794
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #613796 | Mycobacterial and viral infections, susceptibility to, autosomal recessive |
P42224
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #131440 | Myeloproliferative disorder, chronic, with eosinophilia |
P09619
|
| #159900 | Myoclonic dystonia |
P14416
|
| #228550 | Myofibromatosis, infantile, 1; imf1 |
P09619
|
| #613076 | Myopathy, mitochondrial progressive, with congenital cataract, hearing loss, and developmental delay |
P55789
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #163950 | Noonan syndrome 1; ns1 |
Q06124
|
| #601665 | Obesity |
P32245
P37231 |
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
P38398 |
| #614594 | Palmoplantar keratoderma, mutilating, with periorificial keratotic plaques |
Q8NET8
|
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
P37840 |
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #604229 | Peters anomaly |
Q16678
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #217090 | Plasminogen deficiency, type i |
P00747
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #614278 | Platelet-activating factor acetylhydrolase deficiency; pafad |
Q13093
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #176920 | Proteus syndrome |
P31749
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #611131 | Retinitis pigmentosa 37; rp37 |
Q9Y5X4
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #603903 | Sickle cell anemia |
P68871
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #602111 | Spondyloepimetaphyseal dysplasia, missouri type |
P45452
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
O14763
P04637 |
| %612223 | Stature quantitative trait locus 11; stqtl11 |
Q00534
|
| #601367 | Stroke, ischemic |
P00734
|
| #271980 | Succinic semialdehyde dehydrogenase deficiency; ssadhd |
P51649
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #205400 | Tangier disease; tgd |
P02647
|
| #610460 | Thiopurine s-methyltransferase deficiency |
P51580
|
| #187950 | Thrombocythemia 1; thcyt1 |
P40225
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #278300 | Xanthinuria, type i |
P47989
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| #112100 | Yt blood group antigen |
P22303
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00783 | Febrile seizures |
O14764
(related)
P18507 (related) |
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
P04637 (marker) Q16790 (marker) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) P40763 (related) |
| H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P35228 (related) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) P04637 (related) P68871 (marker) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) P04637 (related) P08253 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) P09619 (related) P16234 (related) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00223 | Inherited thrombophilia |
P00734
(related)
P00747 (related) |
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H01206 | Plasminogen deficiency |
P00747
(related)
|
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) Q15046 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00845 | Familial amyloidosis |
P02647
(related)
|
| H00930 | Hypoalphalipoproteinemia |
P02647
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) P04637 (related) Q92731 (marker) |
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
P37840 (related) |
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
P11511 (related) |
| H00019 | Pancreatic cancer |
P04626
(related)
P04637 (related) P04637 (marker) |
| H00027 | Ovarian cancer |
P04626
(related)
P04637 (related) P38398 (related) |
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) P04637 (related) P38398 (related) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P04637 (related) P35354 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
P28907 (marker) Q13315 (related) |
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) P37173 (related) P68871 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P08253 (related) P14780 (related) P35354 (related) |
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
P37231 (related) |
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
P14679 (marker) |
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00101 | Other phagocyte defects |
P11413
(related)
|
| H00668 | Anemia due to disorders of glutathione metabolism |
P11413
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
P45452 (related) |
| H00808 | Idiopathic generalized epilepsies (IGEs) |
P14867
(related)
P18507 (related) |
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00408 | Type I diabetes mellitus |
P17706
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
Q92887 (related) |
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
Q9Y5X4 (related) |
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H00539 | PTEN hamartoma tumor syndrome (PHTS) |
P31749
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00003 | Acute myeloid leukemia (AML) |
P36888
(related)
Q01196 (related) Q01196 (marker) Q13951 (marker) |
| H00800 | Loeys-Dietz syndrome (LDS) |
P37173
(related)
|
| H00801 | Familial thoracic aortic aneurysm and dissection (TAAD) |
P37173
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
| H00107 | Other well-defined immunodeficiency syndromes |
P40763
(related)
|
| H00089 | IFN-gamma/IL-12 axis |
P42224
(related)
|
| H00363 | Candidiasis |
P42224
(related)
|
| H01109 | Chronic mucocutaneous candidiasis (CMC) |
P42224
(related)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
Q99714 (related) |
| H00070 | Galactosemia |
P51570
(related)
|
| H00964 | Thiopurine S-methyltransferase deficiency (TPMT deficiency) |
P51580
(related)
|
| H00835 | Succinic semialdehyde dehydrogenase (SSADH) deficiency |
P51649
(related)
|
| H00931 | Growth hormone insensitivity with immunodeficiency |
P51692
(related)
|
| H00552 | Glycerol kinase deficiency (GKD) |
P51843
(related)
|
| H00607 | 46,XY disorders of sex development (Disorders of gonadal development) |
P51843
(related)
|
| H00606 | Early infantile epileptic encephalopathy |
P53779
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
Q13315 (related) |
| H00296 | Defects in RecQ helicases |
P54132
(related)
Q14191 (related) |
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00228 | Thalassemia |
P68871
(related)
|
| H00229 | Sickle cell anemia (SCA) |
P68871
(related)
|
| H00259 | Apparent mineralocorticoid excess syndrome |
P80365
(related)
|
| H01257 | GABA-transaminase deficiency |
P80404
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00523 | Noonan syndrome and related disorders |
Q02750
(related)
Q06124 (related) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H01018 | Metachondromatosis |
Q06124
(related)
|
| H01258 | Generalized epilepsy and paroxysmal dyskinesia (GEPD) |
Q12791
(related)
|
| H00133 | Mucopolysaccharidosis type IX (MPS9) |
Q12794
(related)
|
| H00421 | Mucopolysaccharidosis (MPS) |
Q12794
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00064 | Ataxia telangiectasia (AT) |
Q13315
(related)
|
| H00848 | Ataxia with ocular apraxia (AOA) |
Q13315
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00612 | Primary open angle glaucoma |
Q16678
(related)
|
| H01075 | Peters anomaly |
Q16678
(related)
|
| H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
| H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00236 | Congenital polycythemia |
Q9GZT9
(related)
|
| H01235 | Bleeding disorder platelet-type |
Q9H244
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
| H00805 | Vitreoretinal degeneration |
Q9Y5X4
(related)
|
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D056486 | Drug-Induced Liver Injury |
C00000968
C00019064 C00003817 |
| D003877 | Dermatitis, Contact |
C00000805
C00000823 |
| D007249 | Inflammation |
C00002743
C00019064 |
| D008106 | Liver Cirrhosis, Experimental |
C00002743
C00019064 |
| D008103 | Liver Cirrhosis |
C00019064
C00000674 |
| D004487 | Edema |
C00001050
C00000819 |
| D011041 | Poisoning |
C00019064
C00003817 |
| D007674 | Kidney Diseases |
C00000823
C00019064 |
| D008107 | Liver Diseases |
C00000823
C00019064 |
| D002252 | Carbon Tetrachloride Poisoning |
C00002743
C00019064 |
| D003110 | Colonic Neoplasms |
C00000968
C00003817 |
| D009374 | Neoplasms, Experimental |
C00003749
C00036880 |
| D009202 | Cardiomyopathies |
C00003749
C00000674 |
| D009062 | Mouth Neoplasms |
C00036880
|
| D006937 | Hypercholesterolemia |
C00003749
|
| D013276 | Stomach Ulcer |
C00000823
|
| D012878 | Skin Neoplasms |
C00003749
|
| D014947 | Wounds and Injuries |
C00003749
|
| D000230 | Adenocarcinoma |
C00000968
|
| D008569 | Memory Disorders |
C00000823
|
| D008114 | Liver Neoplasms, Experimental |
C00000823
|
| D002294 | Carcinoma, Squamous Cell |
C00036880
|
| D006965 | Hyperplasia |
C00036880
|
| D006528 | Carcinoma, Hepatocellular |
C00003749
|
| D012220 | Rhinitis |
C00000856
|
| D009203 | Myocardial Infarction |
C00002743
|
| D020257 | Ventricular Remodeling |
C00003834
|
| D003371 | Cough |
C00000819
|
| D012640 | Seizures |
C00000819
|
| D050171 | Dyslipidemias |
C00019064
|
| D018149 | Glucose Intolerance |
C00019064
|
| D006949 | Hyperlipidemias |
C00019064
|
| D008545 | Melanoma |
C00002743
|
| D017202 | Myocardial Ischemia |
C00019064
|
| D009369 | Neoplasms |
C00019064
|
| D009765 | Obesity |
C00019064
|
| D050197 | Atherosclerosis |
C00002743
|
| D011230 | Precancerous Conditions |
C00019064
|
| D000257 | Adenoviridae Infections |
C00003817
|
| D001943 | Breast Neoplasms |
C00003817
|
| D009361 | Neoplasm Invasiveness |
C00003817
|
| D009362 | Neoplasm Metastasis |
C00003817
|
| D011471 | Prostatic Neoplasms |
C00003817
|
| D002386 | Cataract |
C00000674
|
| D005483 | Flushing |
C00000674
|
| D006529 | Hepatomegaly |
C00000674
|
| D010051 | Ovarian Neoplasms |
C00000674
|