KCF-S cluster No. 749 (12 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (12)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
asterids	35
eudicotyledons	8
Liliopsida	1
rosids	1

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Cumulative family count

class name	count
Lamiaceae	28
Ranunculaceae	8
Apiaceae	5
Boraginaceae	2
Malvaceae	1
Araceae	1

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (12)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002770	Rosmarinic acid	CHEMBL66966 CHEMBL324842 CHEMBL1315100 CHEMBL2111558		48 / 35 / 38
C00037499	Methyl rosmarinate / (+)-Methyl rosmarinate	CHEMBL241405 CHEMBL1765650		6 / 5 / 4
C00037774	Salvianolic acid D
C00041433	Cimicifugic acid A / (+)-Cimicifugic acid A	CHEMBL517537
C00041434	Cimicifugic acid B / (+)-Cimicifugic acid B	CHEMBL500586
C00041435	Cimicifugic acid D / (+)-Cimicifugic acid D	CHEMBL1095596
C00041436	Cimicifugic acid E / (+)-Cimicifugic acid E	CHEMBL1095920
C00041437	Cimicifugic acid F / (+)-Cimicifugic acid F	CHEMBL1097936
C00041438	Cimicifugic acid G	CHEMBL487192		1 / 0 / 0
C00041531	Fukinolic acid	CHEMBL487192	C116090	1 / 0 / 0
C00047808	Clinopodic acid A / (+)-Clinopodic acid A	CHEMBL1079231
C00047809	Clinopodic acid B / (+)-Clinopodic acid B	CHEMBL1080778

Human Protein / Gene in interactions

54 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P34969	5-hydroxytryptamine receptor 7	Serotonin receptor	C00041438 C00041531	0 / 0
P03956	Interstitial collagenase	M10A	C00002770 C00037499	0 / 1
P12931	Proto-oncogene tyrosine-protein kinase Src	Src	C00002770	0 / 0
P14618	Pyruvate kinase PKM	Enzyme	C00002770	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00002770	0 / 3
Q13093	Platelet-activating factor acetylhydrolase	Enzyme	C00002770	3 / 0
P06746	DNA polymerase beta	Enzyme	C00002770	0 / 0
P04062	Glucosylceramidase	Enzyme	C00002770	6 / 4
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00002770	1 / 1
P39900	Macrophage metalloelastase	M10A	C00037499	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00037499	2 / 2
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00002770	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00002770	3 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002770	1 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00002770	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002770	0 / 1
P54132	Bloom syndrome protein	Enzyme	C00002770	1 / 2
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00002770	1 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00002770	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00002770	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00002770	0 / 0
P15121	Aldose reductase	Enzyme	C00002770	0 / 0
P40763	Signal transducer and activator of transcription 3	Transcription Factor	C00002770	1 / 2
Q07820	Induced myeloid leukemia cell differentiation protein Mcl-1	Other cytosolic protein	C00002770	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00002770	1 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00002770	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00002770	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00002770	0 / 0
P45452	Collagenase 3	M10A	C00037499	1 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002770	0 / 0
P08253	72 kDa type IV collagenase	M10A	C00037499	1 / 3
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002770	3 / 3
P51692	Signal transducer and activator of transcription 5B	Unclassified protein	C00002770	1 / 1
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002770	2 / 2
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00002770	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002770	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002770	0 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00002770	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00002770	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00002770	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00002770	4 / 3
P06239	Tyrosine-protein kinase Lck	Src	C00002770	0 / 1
P08254	Stromelysin-1	M10A	C00037499	1 / 0
Q12794	Hyaluronidase-1	Enzyme	C00002770	1 / 2
Q9UBT6	DNA polymerase kappa	Enzyme	C00002770	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002770	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00002770	0 / 0
P42224	Signal transducer and activator of transcription 1-alpha/beta	Unclassified protein	C00002770	3 / 3
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002770	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002770	1 / 1
Q13951	Core-binding factor subunit beta	Unclassified protein	C00002770	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00002770	1 / 4
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002770	0 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00002770	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions