KCF-S cluster No. 174 (34 metabolites)

Corresponding Phytochemical cluster No. 22

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (34)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
asterids	38
rosids	19
eudicotyledons	9
Magnoliophyta	2
Liliopsida	1
Euphyllophyta	1

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Cumulative family count (Top 20)

class name	count
Acanthaceae	6
Asteraceae	6
Menispermaceae	4
Fabaceae	4
Bignoniaceae	4
Loganiaceae	4
Thymelaeaceae	3
Oleaceae	3
Lamiaceae	3
Capparaceae	2
Adoxaceae	2
Eucommiaceae	2
Balanophoraceae	2
Caprifoliaceae	2
Phyllanthaceae	2
Meliaceae	2
Rhizophoraceae	1
Celastraceae	1
Plantaginaceae	1
Magnoliaceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Lignan glycosides	5

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metabolites link (5)

br08003 Category	KEGG ID	KNApSAcK ID
Lignan glycosides	C17048	C00000648
Lignan glycosides	C10560	C00002601
Lignan glycosides	C10885	C00002628
Lignan glycosides	C10890	C00002632
Lignan glycosides	C17529	C00031451

Metabolite list (34)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00000632	Lariciresinol-9-O-beta-D-glucoside
C00000648	(+)-Phillyrin	CHEMBL462767	C075528	1 / 0 / 0
C00002601	Eucommin A	CHEMBL573786 CHEMBL1076999
C00002628	Simplexoside
C00002632	Acanthoside B / Eleutheroside E1 / (+)-Syringaresinol O-beta-D-glucoside / (+)-Syringaresinol 4'-O-beta-glucopyranoside / (+)-Syringaresinol-4-O-beta-D-glucopyranoside	CHEMBL573710 CHEMBL1077080	C087806
C00029302	(+)-Isolariciresinol 2a-O-alpha-L-arabinopyranoside
C00030288	Foliachinenoside C / (-)-Foliachinenoside C
C00030699	Lyoniside / (+)-Lyoniside	CHEMBL466738 CHEMBL583884
C00030720	Tortoside B / Manglieside E / (-)-Manglieside E	CHEMBL1085531
C00030867	Nudiposide	CHEMBL466738 CHEMBL583884
C00031031	(+)-Pinoresinol-beta-D-glucoside / Pinoresinol O-beta-D-glucopyranoside	CHEMBL573336 CHEMBL1083218 CHEMBL1302893		9 / 6 / 4
C00031316	Schizandriside / (+)-Schizandriside	CHEMBL2346750
C00031451	(-)-Pinoresinol O-beta-D-glucopyranoside / (-)-Pinoresinol 4-O-beta-D-glucopyranoside	CHEMBL573336 CHEMBL1083218 CHEMBL1302893		9 / 6 / 4
C00031457	(+)-Pinoresinol monomethyl ether O-beta-D-glucopyranoside
C00031615	Aviculin / (+)-Aviculin
C00032199	Staunoside C
C00032284	Tanegoside
C00032498	Vitecannaside A
C00032499	Vitecannaside B
C00032514	Woorenoside XI / (-)-Woorenoside XI
C00032561	(-)-Massoniresinol 4'-O-beta-D-glucopyranoside
C00032565	(+)-Isolarisiresinol 2a-O-beta-D-glucopyranoside
C00034754	(+)-Cycloolivil 4'-O-beta-D-glucopyranoside
C00036284	(-)-Lyoniresinol 3alpha-O-beta-D-glucopyranoside	CHEMBL464198 CHEMBL1159486 CHEMBL1159487 CHEMBL1813178 CHEMBL1813179 CHEMBL1813180 CHEMBL1813181 CHEMBL2332109		6 / 11 / 5
C00036313	(+)-Lyoniresinol 3alpha-O-beta-glucopyranoside / (+)-Lyoniresinol 3alpha-O-beta-D-glucopyranoside	CHEMBL464198 CHEMBL1159486 CHEMBL1159487 CHEMBL1813178 CHEMBL1813179 CHEMBL1813180 CHEMBL1813181 CHEMBL2332109		6 / 11 / 5
C00036439	1-Hydroxypinoresinol 1-glucoside / 1-Hydroxypinoresinol 1-O-beta-D-glucoside	CHEMBL517863
C00037463	Magnolenin C
C00040746	(+)-Isolarisiresinol 3a-O-beta-D-glucopyranoside	CHEMBL459617
C00043511	Fraxiresinol 4'-O-beta-D-glucopyranoside / (-)-Fraxiresinol 4'-O-beta-D-glucopyranoside	CHEMBL501875
C00043848	Prinsepiol 4-O-beta-D-glucopyranoside	CHEMBL479729
C00044851	Lactucaside / (-)-Lactucaside	CHEMBL499481
C00045470	(-)-Isolariciresinol 3-alpha-O-beta-D-glucopyranoside	CHEMBL459617
C00047703	Alangilignoside C / (+)-Alangilignoside C
C00047704	Alangilignoside D

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00036284 C00036313	0 / 0
P06746	DNA polymerase beta	Enzyme	C00031031 C00031451	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00031031 C00031451	1 / 1
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00036284 C00036313	0 / 0
P37840	Alpha-synuclein	Unclassified protein	C00031031 C00031451	4 / 2
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00031031 C00031451	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00036284 C00036313	7 / 3
Q9Y253	DNA polymerase eta	Enzyme	C00031031 C00031451	1 / 1
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00036284 C00036313	0 / 0
P00734	Prothrombin	S1A	C00036284 C00036313	4 / 2
Q9UNA4	DNA polymerase iota	Enzyme	C00031031 C00031451	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00031031 C00031451	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00031031 C00031451	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00031031 C00031451	0 / 0
Q9P0U3	Sentrin-specific protease 1	Enzyme	C00036284 C00036313	0 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000648	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions