phytochemical cluster No. 22 (64 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• KCF-S cluster (4)
• Metabolite list (64)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
asterids	61
rosids	40
eudicotyledons	11
Magnoliophyta	2
Euphyllophyta	1
Liliopsida	1
Embryophyta	1

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Cumulative family count (Top 20)

class name	count
Acanthaceae	13
Asteraceae	10
Phyllanthaceae	10
Styracaceae	8
Rutaceae	7
Thymelaeaceae	6
Bignoniaceae	5
Loganiaceae	4
Menispermaceae	4
Oleaceae	4
Fabaceae	4
Lamiaceae	3
Caprifoliaceae	2
Adoxaceae	2
Eucommiaceae	2
Apocynaceae	2
Berberidaceae	2
Capparaceae	2
Meliaceae	2
Balanophoraceae	2

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Lignan glycosides	9

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metabolites link (9)

br08003 Category	KEGG ID	KNApSAcK ID
Lignan glycosides	C16915	C00000646
Lignan glycosides	C17048	C00000648
Lignan glycosides	C10548	C00002590
Lignan glycosides	C10560	C00002601
Lignan glycosides	C10870	C00002618
Lignan glycosides	C10876	C00002621
Lignan glycosides	C10885	C00002628
Lignan glycosides	C10890	C00002632
Lignan glycosides	C17529	C00031451

KCF-S cluster (4)

KCF-S ID	# of metabolite
No. 174	34
No. 509	16
No. 653	13
No. 8092	1

Metabolite list (64)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	figure
C00040746	Ciliatoside B / (-)-Ciliatoside B	CHEMBL445172 CHEMBL499379				No. 174
C00000632	(+)-Pinoresinol-beta-D-glucoside / Pinoresinol O-beta-D-glucopyranoside	CHEMBL573336 CHEMBL1083218 CHEMBL1302893		9 / 6 / 4		No. 174
C00047704	beta-Peltatin-O-beta-D-glucopyranoside	CHEMBL401601				No. 174
C00000648	(+)-Phillyrin	CHEMBL462767	C075528	1 / 0 / 0		No. 174
C00037463	Patavine / (-)-Patavine					No. 174
C00002601	Eucommin A	CHEMBL573786 CHEMBL1076999				No. 174
C00047703	Styraxlignolide B / (-)-Styraxlignolide B	CHEMBL519719				No. 174
C00045470	Podorhizol beta-D-glucoside					No. 174
C00002628	Alangilignoside D					No. 174
C00002632	Tanegoside					No. 174
C00029302	Lactucaside / (-)-Lactucaside	CHEMBL499481				No. 174
C00030288	Staunoside C					No. 174
C00030699	Fraxiresinol 4'-O-beta-D-glucopyranoside / (-)-Fraxiresinol 4'-O-beta-D-glucopyranoside	CHEMBL501875				No. 174
C00030720	1-Hydroxypinoresinol 1-glucoside / 1-Hydroxypinoresinol 1-O-beta-D-glucoside	CHEMBL517863				No. 174
C00030867	(-)-Massoniresinol 4'-O-beta-D-glucopyranoside					No. 174
C00036439	4''-O-Acetylmananthoside B	CHEMBL452903				No. 174
C00036313	Diphyllin / Cleistanthin C					No. 174
C00031031	Tortoside B / Manglieside E / (-)-Manglieside E	CHEMBL1085531				No. 174
C00031316	Foliachinenoside C / (-)-Foliachinenoside C					No. 174
C00031451	Magnolenin C					No. 174
C00031457	Acanthoside B / Eleutheroside E1 / (+)-Syringaresinol O-beta-D-glucoside / (+)-Syringaresinol 4'-O-beta-glucopyranoside / (+)-Syringaresinol-4-O-beta-D-glucopyranoside	CHEMBL573710 CHEMBL1077080	C087806			No. 174
C00031615	(+)-Isolarisiresinol 2a-O-beta-D-glucopyranoside					No. 174
C00036284	Arabelline					No. 174
C00034754	Majidine	CHEMBL508105				No. 174
C00044851	Styraxjaponoside A / (+)-Styraxjaponoside A					No. 174
C00032561	(+)-Lyoniresinol 3alpha-O-beta-glucopyranoside / (+)-Lyoniresinol 3alpha-O-beta-D-glucopyranoside	CHEMBL464198 CHEMBL1159486 CHEMBL1159487 CHEMBL1813178 CHEMBL1813179 CHEMBL1813180 CHEMBL1813181 CHEMBL2332109		6 / 11 / 5		No. 174
C00043848	Styraxlignolide C / (-)-Styraxlignolide C	CHEMBL486465				No. 174
C00043511	Styraxlignolide E / (-)-Styraxlignolide E	CHEMBL459834 CHEMBL520065				No. 174
C00032284	Vitecannaside A					No. 174
C00032565	Phyllanthusmin C / (-)-Phyllanthusmin C	CHEMBL460047 CHEMBL1929098		1 / 0 / 0		No. 174
C00032498	Lyoniside / (+)-Lyoniside	CHEMBL466738 CHEMBL583884				No. 174
C00032499	Nudiposide	CHEMBL466738 CHEMBL583884				No. 174
C00032514	(-)-Lyoniresinol 3alpha-O-beta-D-glucopyranoside	CHEMBL464198 CHEMBL1159486 CHEMBL1159487 CHEMBL1813178 CHEMBL1813179 CHEMBL1813180 CHEMBL1813181 CHEMBL2332109		6 / 11 / 5		No. 174
C00032199	(+)-Isolariciresinol 2a-O-alpha-L-arabinopyranoside					No. 174
C00042832	Styraxlignolide D / (-)-Styraxlignolide D	CHEMBL519055				No. 509
C00032712	Acutissimalignan A / (+)-Acutissimalignan A					No. 509
C00033152	Phyllanthusmin B					No. 509
C00033292	Patentiflorin A / (-)-Patentiflorin A	CHEMBL458904 CHEMBL458905 CHEMBL1929103		1 / 0 / 0		No. 509
C00033456	4-O-(3-O-methyl-beta-D-glucopyranosyl)-diphyllin / 4-O-(3''-O-methyl-beta-D-glucopyranosyl)-diphyllin					No. 509
C00033721	Tuberculatin					No. 509
C00033722	Cleistanthin A		C010088			No. 509
C00034173	(2E,6R)-2,6-Dimethyl-8-hydroxy-2-octenoic acid 8-O-[6'-O-(E)-p-coumaroyl]-beta-D-glucopyranoside					No. 509
C00031683	(-)-Isolariciresinol 3-alpha-O-beta-D-glucopyranoside	CHEMBL459617				No. 509
C00035950	Procumbenoside A / (-)-Procumbenoside A	CHEMBL508105				No. 509
C00031682	(+)-Isolarisiresinol 3a-O-beta-D-glucopyranoside	CHEMBL459617				No. 509
C00031018	Alangilignoside C / (+)-Alangilignoside C					No. 509
C00031017	Prinsepiol 4-O-beta-D-glucopyranoside	CHEMBL479729				No. 509
C00002590	(+)-Pinoresinol monomethyl ether O-beta-D-glucopyranoside					No. 509
C00042144	Matairesinoside / (-)-Matairesinoside	CHEMBL459834 CHEMBL520065				No. 509
C00038357	Ciliatoside A / (-)-Ciliatoside A	CHEMBL497767 CHEMBL502183				No. 509
C00000629	(+)-Cycloolivil 4'-O-beta-D-glucopyranoside					No. 653
C00032370	Vitecannaside B					No. 653
C00032217	Aviculin / (+)-Aviculin					No. 653
C00032216	Schizandriside / (+)-Schizandriside	CHEMBL2346750				No. 653
C00043931	Styraxjaponoside B / (-)-Styraxjaponoside B	CHEMBL488098				No. 653
C00043932	Styraxlignolide F / (-)-Styraxlignolide F	CHEMBL488098				No. 653
C00043933	(-)-Arctiin	CHEMBL388452 CHEMBL1526371	C077992	4 / 15 / 11	0 / 2	No. 653
C00000646	(-)-Pinoresinol O-beta-D-glucopyranoside / (-)-Pinoresinol 4-O-beta-D-glucopyranoside	CHEMBL573336 CHEMBL1083218 CHEMBL1302893		9 / 6 / 4		No. 653
C00043935	Tracheloside / (-)-Tracheloside		C079169			No. 653
C00032004	Woorenoside XI / (-)-Woorenoside XI					No. 653
C00002621	Lariciresinol-9-O-beta-D-glucoside					No. 653
C00048330	Phyllanthostatin A	CHEMBL454500	C058885			No. 653
C00043934	(-)-Nortracheloside	CHEMBL574493				No. 653
C00002618	Simplexoside					No. 8092

Human Protein / Gene in interactions

21 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00036284 C00036313	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00031031 C00031451	0 / 0
P06746	DNA polymerase beta	Enzyme	C00031031 C00031451	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00031031 C00031451	1 / 1
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00036284 C00036313	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00036284 C00036313	0 / 0
P37840	Alpha-synuclein	Unclassified protein	C00031031 C00031451	4 / 2
P11388	DNA topoisomerase 2-alpha	Isomerase	C00031018 C00042832	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00031031 C00031451	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00031031 C00031451	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00031031 C00031451	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00031031 C00031451	1 / 1
Q9UBT6	DNA polymerase kappa	Enzyme	C00031031 C00031451	0 / 0
Q9P0U3	Sentrin-specific protease 1	Enzyme	C00036284 C00036313	0 / 0
P00734	Prothrombin	S1A	C00036284 C00036313	4 / 2
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00036284 C00036313	7 / 3
P83916	Chromobox protein homolog 1	Unclassified protein	C00000646	0 / 0
O75496	Geminin	Unclassified protein	C00000646	0 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000648	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00000646	11 / 10
Q16637	Survival motor neuron protein	Unclassified protein	C00000646	4 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions