KCF-S cluster No. 653 (13 metabolites)
Corresponding Phytochemical cluster No. 22
Plant Species
Cumulative plant class count
| class name | count |
|---|---|
| asterids | 15 |
| rosids | 4 |
| eudicotyledons | 2 |
| Embryophyta | 1 |
Cumulative family count
| class name | count |
|---|---|
| Styracaceae | 8 |
| Asteraceae | 4 |
| Thymelaeaceae | 3 |
| Berberidaceae | 2 |
| Selaginellaceae | 1 |
| Symplocaceae | 1 |
| Oleaceae | 1 |
| Apocynaceae | 1 |
| Burseraceae | 1 |
KEGG BRITE br08003
Categories (1)
| br08003 Category | # of metabolite |
|---|---|
| Lignan glycosides | 2 |
metabolites link (2)
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|---|---|
| Lignan glycosides | C16915 | C00000646 |
| Lignan glycosides | C10876 | C00002621 |
Metabolite list (13)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00000629
|
(-)-Nortracheloside
|
CHEMBL574493
|
|
|||
|
C00000646
|
(-)-Arctiin
|
CHEMBL388452
CHEMBL1526371 |
C077992
|
4 / 15 / 11 | 0 / 2 |
|
|
C00002621
|
Podorhizol beta-D-glucoside
|
|
||||
|
C00032004
|
Matairesinoside
/ (-)-Matairesinoside |
CHEMBL459834
CHEMBL520065 |
|
|||
|
C00032216
|
Styraxjaponoside A
/ (+)-Styraxjaponoside A |
|
||||
|
C00032217
|
Styraxjaponoside B
/ (-)-Styraxjaponoside B |
CHEMBL488098
|
|
|||
|
C00032370
|
Tracheloside
/ (-)-Tracheloside |
C079169
|
|
|||
|
C00043931
|
Styraxlignolide B
/ (-)-Styraxlignolide B |
CHEMBL519719
|
|
|||
|
C00043932
|
Styraxlignolide C
/ (-)-Styraxlignolide C |
CHEMBL486465
|
|
|||
|
C00043933
|
Styraxlignolide D
/ (-)-Styraxlignolide D |
CHEMBL519055
|
|
|||
|
C00043934
|
Styraxlignolide E
/ (-)-Styraxlignolide E |
CHEMBL459834
CHEMBL520065 |
|
|||
|
C00043935
|
Styraxlignolide F
/ (-)-Styraxlignolide F |
CHEMBL488098
|
|
|||
|
C00048330
|
beta-Peltatin-O-beta-D-glucopyranoside
|
CHEMBL401601
|
|
Human Protein / Gene in interactions
4 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q16637 | Survival motor neuron protein | Unclassified protein | C00000646 | 4 / 1 |
| P02545 | Prelamin-A/C | Unclassified protein | C00000646 | 11 / 10 |
| O75496 | Geminin | Unclassified protein | C00000646 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000646 | 0 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (15)
| OMIM | preferred title | UniProt |
|---|---|---|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
KEGG DISEASE (11)
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|