PCIDB

KNApSAcK Metabolite C00001017

Metabolite

KNApSAcK Entry

id C00001017
Name Cosmosiin / Apigenin 7-glucoside / (-)-Apigenin 7-glucoside / Apigenin 7-O-beta-D-glucopyranoside
CAS RN 578-74-5
Standard InChI InChI=1S/C21H20O10/c22-8-16-18(26)19(27)20(28)21(31-16)29-11-5-12(24)17-13(25)7-14(30-15(17)6-11)9-1-3-10(23)4-2-9/h1-7,16,18-24,26-28H,8H2/t16?,18-,19+,20?,21-/m1/s1
Standard InChI (Main Layer) InChI=1S/C21H20O10/c22-8-16-18(26)19(27)20(28)21(31-16)29-11-5-12(24)17-13(25)7-14(30-15(17)6-11)9-1-3-10(23)4-2-9/h1-7,16,18-24,26-28H,8H2

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 2

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL487995 CHEMBL487017 CHEMBL1591566 CHEMBL2165585

KEGG

By LinkDB C04608

CTD

By CAS RN C057792

Species

Summary

Plant class

class name count
asterids 40
rosids 8
Liliopsida 2
Embryophyta 2
eudicotyledons 1
Magnoliophyta 1
Euphyllophyta 1

Family (Top 10)

family name count
Lamiaceae 22
Asteraceae 8
Fabaceae 3
Euphorbiaceae 2
Plantaginaceae 2
Oleaceae 1
Iridaceae 1
Pteridaceae 1
Crassulaceae 1
Acanthaceae 1

List (57)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Achillea atrata L.ssp.multifida 13328 Asteraceae asterids Viridiplantae
Asphodeline globifera 49695 Xanthorrhoeaceae Liliopsida Viridiplantae
Asystasia gangetica L. 141291 Acanthaceae asterids Viridiplantae
Ballota foetida 155228 Lamiaceae asterids Viridiplantae
Bellis perennis 41492 Asteraceae asterids Viridiplantae
Cadia purpurea 53844 Fabaceae rosids Viridiplantae
Chamomilla recutita (L.) Rauschert
Chrysanthemum indicum 146995 Asteraceae asterids Viridiplantae
Codonopsis clematidea 942849 Campanulaceae asterids Viridiplantae
Conocephalum conicum 41839 Conocephalaceae Embryophyta Viridiplantae
Cosmos bipinnatus 51277 Asteraceae asterids Viridiplantae
Crocus chrysanthus-biflorus 58949 Iridaceae Liliopsida Viridiplantae
Elsholtzia bodinieri 41225 Lamiaceae asterids Viridiplantae
Euphorbia prostrata 212836 Euphorbiaceae rosids Viridiplantae
Gentiana loureirii 21496 Gentianaceae asterids Viridiplantae
Hebe parviflora 163752 Plantaginaceae asterids Viridiplantae
Helichrysum graveolen 59430 Asteraceae asterids Viridiplantae
Hornschuchia citriodora 306963 Annonaceae Magnoliophyta Viridiplantae
Leucophyllum ambiguum 69911 Scrophulariaceae asterids Viridiplantae
Ligustrum robustum 1028359 Oleaceae asterids Viridiplantae
Lupinus albus L. 3870 Fabaceae rosids Viridiplantae
Ocimum sanctum 204149 Lamiaceae asterids Viridiplantae
Onosma hispida 411249 Boraginaceae asterids Viridiplantae
Phlomis nissolii 997732 Lamiaceae asterids Viridiplantae
Physocarpus capitatus 141000 Rosaceae rosids Viridiplantae
Plantago lanceolata 39414 Plantaginaceae asterids Viridiplantae
Prostanthera melissifolia 1290920 Lamiaceae asterids Viridiplantae
Pteris multifida 170715 Pteridaceae Euphyllophyta Viridiplantae
Retama raetam 49837 Fabaceae rosids Viridiplantae
Riella affinis
Riella americana 122650 Riellaceae Embryophyta Viridiplantae
Salix viminalis L. 40686 Salicaceae rosids Viridiplantae
Salvia aegypteacae 21880 Lamiaceae asterids Viridiplantae
Salvia aegyptiaca 392645 Lamiaceae asterids Viridiplantae
Salvia albimaculata 21880 Lamiaceae asterids Viridiplantae
Salvia calycina 21880 Lamiaceae asterids Viridiplantae
Salvia horminum 21880 Lamiaceae asterids Viridiplantae
Salvia lanigera 21880 Lamiaceae asterids Viridiplantae
Salvia lavandulaefolia 49214 Lamiaceae asterids Viridiplantae
Salvia limbata 21880 Lamiaceae asterids Viridiplantae
Salvia officinalis 38868 Lamiaceae asterids Viridiplantae
Salvia palaestina 268920 Lamiaceae asterids Viridiplantae
Salvia pinnata 21880 Lamiaceae asterids Viridiplantae
Salvia pratensis 49216 Lamiaceae asterids Viridiplantae
Salvia spinosa 21880 Lamiaceae asterids Viridiplantae
Salvia triloba 21880 Lamiaceae asterids Viridiplantae
Santolina chamaecyperissus 41642 Asteraceae asterids Viridiplantae
Saussurea medusa 137893 Asteraceae asterids Viridiplantae
Sedum sarmentosum 91146 Crassulaceae eudicotyledons Viridiplantae
Stachys germanica L. 876252 Lamiaceae asterids Viridiplantae
Stachys lanata 53171 Lamiaceae asterids Viridiplantae
Stachys plumosa Griseb. 1081576 Lamiaceae asterids Viridiplantae
Strophioblachia fimbricalyx Boerl 179701 Euphorbiaceae rosids Viridiplantae
Theobroma cacao L. 3640 Malvaceae rosids Viridiplantae
Torenia fournieri 68875 Linderniaceae asterids Viridiplantae
Trachelospermum asiaticum var.intermedium 69388 Apocynaceae asterids Viridiplantae
Zinnia elegans 34245 Asteraceae asterids Viridiplantae

Human Protein / Gene in interaction

5 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q16637 Survival motor neuron protein Unclassified protein CHEMBL1591566 CHEMBL1613842 (1)
4 / 2
P83916 Chromobox protein homolog 1 Unclassified protein CHEMBL487995 CHEMBL1794401 (1)
0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme CHEMBL1591566 CHEMBL1794467 (1)
0 / 0
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette CHEMBL487017 CHEMBL1687393 (1) CHEMBL1687394 (1)
2 / 0
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL1591566 CHEMBL1794536 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#614490 Blood group, junior system; jr Q9UNQ0
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0

KEGG DISEASE (1)

KEGG disease name UniProt
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
Q16637 (related)