Trachelospermum asiaticum var.intermedium

• Index
• Plant Species
• Metabolite list (8)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Trachelospermum asiaticum var.intermedium
Genus	Trachelospermum
Family	Apocynaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Trachelospermum
Linked NCBI taxonomy ID	69388
Linked level	genus

Family

Family in NCBI taxonomy	Apocynaceae
ID	4056

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (8)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00004283	Lonicerin / Luteolin 7-neohesperidoside	CHEMBL452979	C009652	1 / 1 / 1		No. 1	No. 15
C00004157	Rhoifolin / (-)-Rhoifolin	CHEMBL395990 CHEMBL1888642	C089378	2 / 0 / 3		No. 1	No. 15
C00005374	Quercetin	CHEMBL82242 CHEMBL479232 CHEMBL1437696	C012526	14 / 2 / 2	2 / 1	No. 2	No. 15
C00001017	Cosmosiin / Apigenin 7-glucoside / (-)-Apigenin 7-glucoside / Apigenin 7-O-beta-D-glucopyranoside	CHEMBL487995 CHEMBL487017 CHEMBL1591566 CHEMBL2165585	C057792	5 / 6 / 1		No. 2	No. 15
C00005140	Afzelin / Kaempferol 3-O-alpha-rhamnoside / Kaempferol 3-O-alpha-L-rhamnopyranoside	CHEMBL240528 CHEMBL515798	C477954	4 / 2 / 2		No. 2	No. 15
C00002724	Heriguard / Chlorogenic acid / 3-O-Caffeoylquinic acid	CHEMBL284616 CHEMBL230481 CHEMBL249450 CHEMBL1332980 CHEMBL1394423 CHEMBL1419611 CHEMBL1473644 CHEMBL1552319	D002726	30 / 19 / 22	37 / 9	No. 314	No. 6
C00029948	Methyl chlorogenate / Methyl 5-O-caffeoylquinate / Chlorogenic acid methyl ester	CHEMBL416955 CHEMBL596924 CHEMBL1765881 CHEMBL1765882 CHEMBL2048503 CHEMBL2349427		6 / 5 / 4		No. 314	No. 6
C00032370	Tracheloside / (-)-Tracheloside		C079169			No. 653	No. 22

Human Protein / Gene in interactions

50 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002724 C00005140	1 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002724 C00005374	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00001017 C00005374	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00002724 C00005374	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00002724 C00004157	0 / 3
O75164	Lysine-specific demethylase 4A	Enzyme	C00002724 C00005374	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002724 C00005140	0 / 1
P00352	Retinal dehydrogenase 1	Enzyme	C00002724 C00005374	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00001017 C00004157	0 / 0
P15121	Aldose reductase	Enzyme	C00002724 C00005374	0 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00004283 C00005374	1 / 1
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002724 C00005374	0 / 0
P07237	Protein disulfide-isomerase	Enzyme	C00005374	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002724	0 / 1
P39748	Flap endonuclease 1	Enzyme	C00005374	0 / 0
O75496	Geminin	Unclassified protein	C00002724	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00002724	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00002724	3 / 2
P10145	Interleukin-8	Secreted protein	C00002724	0 / 0
P40763	Signal transducer and activator of transcription 3	Transcription Factor	C00002724	1 / 2
P03956	Interstitial collagenase	M10A	C00029948	0 / 1
Q9Y253	DNA polymerase eta	Enzyme	C00005374	1 / 1
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00005374	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00001017	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00029948	2 / 2
P39900	Macrophage metalloelastase	M10A	C00029948	0 / 0
P16083	Ribosyldihydronicotinamide dehydrogenase [quinone]	Enzyme	C00005140	0 / 0
P12931	Proto-oncogene tyrosine-protein kinase Src	Src	C00002724	0 / 0
P45452	Collagenase 3	M10A	C00029948	1 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002724	0 / 0
P08253	72 kDa type IV collagenase	M10A	C00029948	1 / 3
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002724	3 / 3
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00001017	2 / 0
P51692	Signal transducer and activator of transcription 5B	Unclassified protein	C00002724	1 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002724	1 / 1
Q13093	Platelet-activating factor acetylhydrolase	Enzyme	C00002724	3 / 0
P98170	E3 ubiquitin-protein ligase XIAP	Other cytosolic protein	C00005140	1 / 1
Q9UNA4	DNA polymerase iota	Enzyme	C00005374	0 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00002724	2 / 2
O60218	Aldo-keto reductase family 1 member B10	Enzyme	C00002724	0 / 0
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00002724	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002724	0 / 0
P06239	Tyrosine-protein kinase Lck	Src	C00002724	0 / 1
P08254	Stromelysin-1	M10A	C00029948	1 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00001017	4 / 1
Q9P1W9	Serine/threonine-protein kinase pim-2	Pim	C00005374	0 / 0
P42224	Signal transducer and activator of transcription 1-alpha/beta	Unclassified protein	C00002724	3 / 3
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002724	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002724	1 / 1
P04150	Glucocorticoid receptor	NR3C1	C00002724	0 / 1

39 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00005374
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00005374
47	ACLY, ACL, ATPCL, CLATP	ATP citrate lyase (EC:2.3.3.8)	C00002724
358	AQP1, AQP-CHIP, CHIP28, CO	aquaporin 1	C00002724
360	AQP3, AQP-3, GIL	aquaporin 3 (Gill blood group)	C00002724
367	AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM	androgen receptor	C00002724
960	CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1	CD44 molecule (Indian blood group)	C00002724
999	CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO	cadherin 1, type 1, E-cadherin (epithelial)	C00002724
1277	COL1A1, OI4	collagen, type I, alpha 1	C00002724
4512	COX1, COI, MTCO1, MT-CO1	cytochrome c oxidase subunit I	C00002724
114757	CYGB, HGB, STAP	cytoglobin	C00002724
1830	DSG3, CDHF6, PVA	desmoglein 3	C00002724
1950	EGF, HOMG4, URG	epidermal growth factor	C00002724
2200	FBN1, ACMICD, ECTOL1, FBN, GPHYSD2, MASS, MFS1, OCTD, SGS, SSKS, WMS, WMS2	fibrillin 1	C00002724
2201	FBN2, CCA, DA9	fibrillin 2	C00002724
2246	FGF1, AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-1, FGF-alpha, FGFA, GLIO703, HBGF-1, HBGF1	fibroblast growth factor 1 (acidic)	C00002724
2896	GRN, CLN11, GEP, GP88, PCDGF, PEPI, PGRN	granulin	C00002724
3036	HAS1, HAS	hyaluronan synthase 1 (EC:2.4.1.212)	C00002724
3315	HSPB1, CMT2F, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27	heat shock 27kDa protein 1	C00002724
3552	IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1	interleukin 1, alpha	C00002724
3852	KRT5, CK5, DDD, DDD1, EBS2, K5, KRT5A	keratin 5	C00002724
4157	MC1R, CMM5, MSH-R, SHEP2	melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)	C00002724
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00002724
5241	PGR, NR3C3, PR	progesterone receptor	C00002724
8985	PLOD3, LH3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (EC:1.14.11.4)	C00002724
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00002724
5886	RAD23A, HHR23A, HR23A	RAD23 homolog A (S. cerevisiae)	C00002724
5914	RARA, NR1B1, RAR	retinoic acid receptor, alpha	C00002724
6256	RXRA, NR2B1	retinoid X receptor, alpha	C00002724
6649	SOD3, EC-SOD	superoxide dismutase 3, extracellular (EC:1.15.1.1)	C00002724
6716	SRD5A2	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (EC:1.3.1.22)	C00002724
7178	TPT1, HRF, TCTP, p02, p23	tumor protein, translationally-controlled 1	C00002724
7295	TXN, TRDX, TRX, TRX1	thioredoxin	C00002724
7299	TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3	tyrosinase (EC:1.14.18.1)	C00002724
7306	TYRP1, CAS2, CATB, GP75, OCA3, TRP, TRP1, TYRP, b-PROTEIN	tyrosinase-related protein 1 (EC:1.14.18.-)	C00002724
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00002724
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00002724
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00002724
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00002724

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions