KNApSAcK Metabolite C00005374
Metabolite
KNApSAcK Entry
| id | C00005374 |
|---|---|
| Name | Quercetin |
| CAS RN | 522-12-3 |
| Standard InChI | InChI=1S/C21H20O11/c1-7-15(26)17(28)18(29)21(30-7)32-20-16(27)14-12(25)5-9(22)6-13(14)31-19(20)8-2-3-10(23)11(24)4-8/h2-7,15,17-18,21-26,28-29H,1H3/t7?,15-,17?,18-,21-/m0/s1 |
| Standard InChI (Main Layer) | InChI=1S/C21H20O11/c1-7-15(26)17(28)18(29)21(30-7)32-20-16(27)14-12(25)5-9(22)6-13(14)31-19(20)8-2-3-10(23)11(24)4-8/h2-7,15,17-18,21-26,28-29H,1H3 |
Cluster
| Phytochemical cluster | No. 15 |
|---|---|
| KCF-S cluster | No. 2 |
Link
ChEMBL
| By standard InChI | |
|---|---|
| By standard InChI Main Layer | CHEMBL82242 CHEMBL479232 CHEMBL1437696 |
KEGG
| By LinkDB | C01750 |
|---|
CTD
| By CAS RN | C012526 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| rosids | 72 |
| asterids | 37 |
| eudicotyledons | 13 |
| Spermatophyta | 11 |
| Liliopsida | 4 |
| Magnoliophyta | 4 |
| Euphyllophyta | 2 |
Family (Top 10)
| family name | count |
|---|---|
| Fabaceae | 20 |
| Asteraceae | 17 |
| Hypericaceae | 10 |
| Myrtaceae | 7 |
| Cupressaceae | 5 |
| Euphorbiaceae | 4 |
| Casuarinaceae | 4 |
| Apiaceae | 3 |
| Rosaceae | 3 |
| Anacardiaceae | 3 |
List (150)
* NCBI
Human Protein / Gene in interaction
14 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| Q9P1W9 | Serine/threonine-protein kinase pim-2 | Pim | CHEMBL82242 |
CHEMBL931462
(1)
|
0 / 0 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | CHEMBL82242 |
CHEMBL1014040
(1)
CHEMBL1023248
(1)
|
1 / 1 |
| P07237 | Protein disulfide-isomerase | Enzyme | CHEMBL82242 |
CHEMBL1964080
(1)
CHEMBL2114805
(1)
|
0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | CHEMBL1437696 |
CHEMBL1614458
(1)
|
0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | CHEMBL82242 |
CHEMBL1794486
(1)
|
0 / 0 |
| P15121 | Aldose reductase | Enzyme | CHEMBL82242 |
CHEMBL936594
(1)
CHEMBL1036011
(1)
CHEMBL1036012 (1) CHEMBL1036013 (1) CHEMBL1036014 (1) CHEMBL1942674 (1) |
0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | CHEMBL82242 |
CHEMBL1794569
(1)
|
1 / 1 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | CHEMBL82242 |
CHEMBL1614280
(1)
|
0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | CHEMBL82242 |
CHEMBL1794483
(1)
|
0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | CHEMBL82242 |
CHEMBL1737991
(1)
|
0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | CHEMBL1437696 |
CHEMBL1614211
(1)
|
0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | CHEMBL82242 CHEMBL1437696 |
CHEMBL1794536
(2)
|
0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | CHEMBL1437696 |
CHEMBL1613914
(1)
|
0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | CHEMBL82242 |
CHEMBL2114738
(1)
|
0 / 0 |
CTD interaction (2)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C012526 | 1543 |
CYP1A1
AHH AHRR CP11 CYP1 P1-450 P450-C P450DX |
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | quercitrin results in decreased activity of CYP1A1 protein |
decreases activity
|
protein |
16271822
|
| C012526 | 1545 |
CYP1B1
CP1B CYPIB1 GLC3A P4501B1 |
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | quercitrin results in decreased activity of CYP1B1 protein |
decreases activity
|
protein |
16271822
|