Species

KNApSAcK Entry

Organism name Hippophae rhamnoides
Genus Hippophae
Family Elaeagnaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Hippophae rhamnoides
Linked NCBI taxonomy ID 193516
Linked level species

Family

Family in NCBI taxonomy Elaeagnaceae
ID 25996

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (18)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00007247 External link 512 Linolenic acid
/ alpha-Linolenic acid
/ (Z,Z,Z)-Octadeca-9,12,15-trienoic acid
D017962
22 / 5
C00005557 External link 512 Isorhamnetin 3-glucoside-7-rhamnoside
/ Isorhamnetin 3-O-beta-glucopyranoside-7-O-alpha-rhamnopyranoside
No. 1 No. 15
C00005539 External link 512 Isorhamnetin 3-vicianoside
No. 1 No. 15
C00005544 External link 512 Isorhamnetin 3-sophoroside
No. 1 No. 15
C00005548 External link 512 Narcissin
/ Isorhamnetin 3-O-rutinoside
CHEMBL84174
CHEMBL258394
CHEMBL1711509
CHEMBL2165403
C031062
7 / 1 / 2 No. 1 No. 15
C00005531 External link 512 Isorhamnetin 7-rhamnoside
No. 2 No. 15
C00005374 External link 512 Quercetin
CHEMBL82242
CHEMBL479232
CHEMBL1437696
C012526
14 / 2 / 2 2 / 1 No. 2 No. 15
C00001071 External link 512 Myricetin
CHEMBL164
C040015
78 / 70 / 56 39 / 2 No. 3 No. 15
C00004635 External link 512 Isorhamnetin
/ 3'-O-Methylquercetin
/ 3,4',5,7-Tetrahydroxy-3'-methoxyflavone
/ 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one
CHEMBL379064
C047368
12 / 10 / 13 10 / 0 No. 3 No. 15
C00005580 External link 512 Isorhamnetin 3-sophoroside-7-rhamnoside
No. 5 No. 15
C00004565 External link 512 Kaempferol
/ Nimbecetin
/ Rhamnolutein
/ Pelargidenolon
/ 5,7,4'-Trihydroxyflavonol
/ 3,5,7,4'-Tetrahydroxyflavone
/ 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
CHEMBL150
C006552
76 / 69 / 87 86 / 8 No. 71 No. 15
C00003766 External link 512 delta-Carotene
No. 131 No. 59
C00029354 External link 512 Palmitoleic acid
/ cis-Palmitoleic acid
/ (Z)-Palmitoleic acid
CHEMBL453509
2 / 5 / 3 No. 184 No. 68
C00008882 External link 512 Gallocatechin 3-O-gallate
CHEMBL297453
CHEMBL311663
CHEMBL126079
CHEMBL338988
CHEMBL264938
49 / 48 / 54 No. 219 No. 14
C00002647 External link 512 Gallic acid
CHEMBL288114
D005707
42 / 53 / 68 52 / 16 No. 817 No. 81
C00031437 External link 512 Vitamin A
CHEMBL986
CHEMBL1454290
CHEMBL1595345
28 / 26 / 26 No. 1438
C00001429 External link 512 Serotonin
/ Enteramin
/ Enteramine
/ DS substance
/ Thrombotonin
/ Thrombocytin
/ 5-Hydroxytryptamine
CHEMBL39
CHEMBL1628597
D012701
78 / 35 / 22 32 / 40 No. 1910 No. 4
C00001179 External link 512 Vitamin C
/ L-Ascorbate
/ L-Ascorbic acid
/ (+)-Ascorbic acid
CHEMBL196
CHEMBL1161421
D001205
104 / 58 / 50 254 / 98 No. 8774

Human Protein / Gene in interactions

293 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001071 C00001179 C00001429 C00004565 C00005548 C00008882 C00031437 0 / 1
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001071 C00001179 C00002647 C00004565 C00004635 C00005374 C00008882 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00001071 C00001179 C00001429 C00002647 C00004565 C00008882 0 / 3
P10636 Microtubule-associated protein tau Unclassified protein C00001071 C00001179 C00002647 C00004565 C00008882 C00031437 4 / 3
P00352 Retinal dehydrogenase 1 Enzyme C00001071 C00002647 C00004565 C00005374 C00008882 C00031437 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00001071 C00001429 C00002647 C00008882 C00031437 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00001071 C00004565 C00005374 C00005548 C00031437 0 / 0
P03372 Estrogen receptor NR3A1 C00001179 C00002647 C00004565 C00005548 C00031437 1 / 1
O00255 Menin Unclassified protein C00001071 C00004565 C00004635 C00008882 C00031437 2 / 5
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001071 C00002647 C00004565 C00005374 C00008882 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00001071 C00002647 C00004635 C00005374 C00008882 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001071 C00001179 C00001429 C00004565 C00004635 0 / 0
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00001071 C00004565 C00004635 C00008882 C00031437 1 / 2
P11473 Vitamin D3 receptor NR1I1 C00001071 C00001179 C00002647 C00008882 C00031437 2 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00001179 C00002647 C00004565 C00008882 C00031437 0 / 0
P04745 Alpha-amylase 1 Enzyme C00001071 C00001179 C00004565 C00004635 0 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00004565 C00008882 C00029354 C00031437 5 / 3
P04150 Glucocorticoid receptor NR3C1 C00001179 C00002647 C00004565 C00031437 0 / 1
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00001071 C00004565 C00008882 C00031437 0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00001071 C00004565 C00004635 C00005374 1 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001071 C00001179 C00001429 C00004565 1 / 1
P15121 Aldose reductase Enzyme C00001071 C00002647 C00004565 C00005374 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001071 C00001179 C00001429 C00004565 0 / 1
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00001179 C00004565 C00008882 C00031437 2 / 2
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00001071 C00002647 C00004565 C00008882 1 / 1
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00001071 C00002647 C00004565 C00008882 3 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00001071 C00002647 C00004565 C00008882 2 / 2
P39748 Flap endonuclease 1 Enzyme C00001071 C00004565 C00004635 C00005374 0 / 0
P22303 Acetylcholinesterase Hydrolase C00001071 C00001179 C00001429 C00004565 1 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00001071 C00004565 C00008882 C00031437 0 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00001179 C00001429 C00004565 C00008882 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001071 C00001179 C00001429 C00004565 1 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00001179 C00002647 C00008882 C00031437 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00001071 C00004565 C00005374 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00001071 C00002647 C00005374 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00001429 C00002647 C00008882 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00001071 C00001429 C00008882 0 / 0
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 C00001071 C00004565 C00004635 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00001071 C00004565 C00005374 1 / 1
P14679 Tyrosinase Oxidoreductase C00001179 C00001429 C00004565 4 / 2
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 C00001071 C00004565 C00004635 4 / 4
P00918 Carbonic anhydrase 2 Lyase C00001179 C00001429 C00002647 1 / 2
P02545 Prelamin-A/C Unclassified protein C00001179 C00002647 C00004565 11 / 10
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00001071 C00008882 C00031437 0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00001071 C00001179 C00001429 0 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00002647 C00004565 7 / 37
Q16790 Carbonic anhydrase 9 Lyase C00001429 C00002647 0 / 1
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00001429 C00002647 5 / 1
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00004565 C00031437 0 / 0
P33765 Adenosine receptor A3 Adenosine receptor C00001179 C00001429 0 / 0
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00004565 C00031437 0 / 0
P08581 Hepatocyte growth factor receptor TK tyrosine-protein kinase MET subfamily C00002647 C00008882 2 / 3
P16473 Thyrotropin receptor Glycohormone receptor C00001429 C00031437 3 / 2
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00004565 C00004635 0 / 0
P07451 Carbonic anhydrase 3 Lyase C00001429 C00002647 0 / 0
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00004565 C00031437 0 / 0
P04062 Glucosylceramidase Enzyme C00001071 C00004565 6 / 4
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor C00001179 C00001429 0 / 0
P06276 Cholinesterase Hydrolase C00001071 C00004565 0 / 0
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00001179 C00031437 1 / 1
Q16539 Mitogen-activated protein kinase 14 p38 C00001179 C00008882 0 / 0
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00001179 C00008882 5 / 9
P49798 Regulator of G-protein signaling 4 Unclassified protein C00001071 C00001429 2 / 0
P31645 Sodium-dependent serotonin transporter Serotonin C00001179 C00001429 2 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00001179 C00001429 0 / 0
Q99700 Ataxin-2 Unclassified protein C00001071 C00004565 1 / 1
Q04760 Lactoylglutathione lyase Enzyme C00001071 C00004565 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00001071 C00008882 0 / 0
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00001071 C00005374 0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor C00001179 C00001429 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00001179 C00004565 0 / 0
P11309 Serine/threonine-protein kinase pim-1 Pim C00001071 C00004565 0 / 0
P06746 DNA polymerase beta Enzyme C00001071 C00008882 0 / 0
P00915 Carbonic anhydrase 1 Lyase C00001429 C00002647 0 / 0
P10145 Interleukin-8 Secreted protein C00002647 C00031437 0 / 0
P22748 Carbonic anhydrase 4 Lyase C00001429 C00002647 1 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor C00001179 C00001429 0 / 0
P35462 D(3) dopamine receptor Dopamine receptor C00001179 C00001429 1 / 0
O75496 Geminin Unclassified protein C00005548 C00031437 0 / 0
P43166 Carbonic anhydrase 7 Lyase C00001429 C00002647 0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00001429 C00002647 0 / 0
P08246 Neutrophil elastase S1A C00001179 C00008882 2 / 1
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00001071 C00004565 0 / 0
P07237 Protein disulfide-isomerase Enzyme C00005374 C00005548 0 / 0
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr C00001071 C00004565 1 / 1
O43570 Carbonic anhydrase 12 Lyase C00001429 C00002647 1 / 2
P54132 Bloom syndrome protein Enzyme C00001071 C00008882 1 / 2
P22310 UDP-glucuronosyltransferase 1-4 Enzyme C00001429 C00031437 3 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase C00001429 C00002647 0 / 0
O15296 Arachidonate 15-lipoxygenase B Enzyme C00001071 C00004565 0 / 0
Q9Y3R4 Sialidase-2 Enzyme C00001071 C00004565 0 / 0
P23280 Carbonic anhydrase 6 Lyase C00001429 C00002647 0 / 0
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00001179 C00004565 1 / 8
P33527 Multidrug resistance-associated protein 1 drugs C00001071 C00004565 0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00001071 C00004565 0 / 0
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00001429 C00002647 0 / 0
P14416 D(2) dopamine receptor Dopamine receptor C00001179 C00001429 2 / 0
P14151 L-selectin Adhesion C00002647 0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor C00001179 0 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00001179 0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor C00001179 0 / 0
P29274 Adenosine receptor A2a Adenosine receptor C00001179 0 / 0
P13674 Prolyl 4-hydroxylase subunit alpha-1 Enzyme C00001179 0 / 0
Q15746 Myosin light chain kinase, smooth muscle Mlck C00001071 1 / 1
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor C00001179 0 / 0
P05164 Myeloperoxidase Enzyme C00001429 1 / 2
Q96KS0 Egl nine homolog 2 Enzyme C00001179 0 / 0
P28566 5-hydroxytryptamine receptor 1E Serotonin receptor C00001429 0 / 0
Q9GZU7 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 Enzyme C00004565 0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor C00001179 1 / 1
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00001071 1 / 0
P17948 Vascular endothelial growth factor receptor 1 Vegfr C00001179 0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor C00001179 1 / 0
Q9HC97 G-protein coupled receptor 35 Kynurenic acid receptor C00001071 0 / 0
P51570 Galactokinase Enzyme C00008882 1 / 1
P50281 Matrix metalloproteinase-14 M10A C00008882 0 / 0
P16581 E-selectin Adhesion C00002647 0 / 0
P04792 Heat shock protein beta-1 Unclassified protein C00004635 2 / 1
Q9GZT9 Egl nine homolog 1 Enzyme C00001179 1 / 1
P02753 Retinol-binding protein 4 Secreted protein C00031437 1 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00001179 0 / 0
Q15078 Cyclin-dependent kinase 5 activator 1 REG serine/threonine protein kinase family C00004565 0 / 0
Q00535 Cyclin-dependent kinase 5 Cdk5 C00004565 0 / 0
P16662 UDP-glucuronosyltransferase 2B7 Enzyme C00001429 0 / 0
Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor Enzyme C00001179 0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr C00001179 0 / 0
P54855 UDP-glucuronosyltransferase 2B15 Enzyme C00001429 0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase C00001179 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00001179 0 / 0
P21917 D(4) dopamine receptor Dopamine receptor C00001179 0 / 0
P30988 Calcitonin receptor Calcitonin receptor C00001179 0 / 0
P06241 Tyrosine-protein kinase Fyn Src C00001179 0 / 0
P41143 Delta-type opioid receptor Opioid receptor C00001179 0 / 0
P46098 5-hydroxytryptamine receptor 3A NS C00001429 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00001179 0 / 1
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor C00001179 0 / 0
P49327 Fatty acid synthase Transferase C00008882 0 / 0
P25101 Endothelin-1 receptor Endothelin receptor C00001179 0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor C00001179 0 / 0
P78536 Disintegrin and metalloproteinase domain-containing protein 17 M12B C00002647 1 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor C00001179 1 / 0
P08183 Multidrug resistance protein 1 drug C00004565 1 / 0
P02768 Serum albumin Secreted protein C00008882 0 / 0
Q14790 Caspase-8 C14 C00001071 2 / 1
P32238 Cholecystokinin receptor type A Cholecystokinin receptor C00001179 0 / 0
P08311 Cathepsin G S1A C00001179 0 / 0
P27487 Dipeptidyl peptidase 4 S9B C00004565 0 / 1
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00001179 1 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00005548 0 / 0
Q12791 Calcium-activated potassium channel subunit alpha-1 KCNM, KCa1.x C00004565 1 / 1
P03956 Interstitial collagenase M10A C00001179 0 / 1
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor C00001179 0 / 0
P47898 5-hydroxytryptamine receptor 5A Serotonin receptor C00001429 0 / 0
P09923 Intestinal-type alkaline phosphatase Enzyme C00001071 0 / 0
P05186 Alkaline phosphatase, tissue-nonspecific isozyme Enzyme C00001071 3 / 1
Q00534 Cyclin-dependent kinase 6 CMGC serine/threonine protein kinase family C00004565 1 / 0
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor C00001429 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00001071 0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00001071 0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor C00001179 0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00001179 0 / 0
P06213 Insulin receptor TK tyrosine-protein kinase INSR subfamily C00001071 5 / 4
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00001179 2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00001179 0 / 0
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 C00001071 2 / 2
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor C00001179 0 / 0
P21554 Cannabinoid receptor 1 Cannabinoid receptor C00001179 0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine C00001179 1 / 0
P35367 Histamine H1 receptor Histamine receptor C00001179 0 / 0
P28222 5-hydroxytryptamine receptor 1B Serotonin receptor C00001429 0 / 0
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00001179 1 / 0
P25021 Histamine H2 receptor Histamine receptor C00001179 0 / 0
P21452 Substance-K receptor Neurokinin receptor C00001179 0 / 0
P10276 Retinoic acid receptor alpha NR1B1 C00031437 1 / 2
P51679 C-C chemokine receptor type 4 CC chemokine receptor C00001179 0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor C00001179 3 / 0
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00001179 0 / 1
P36544 Neuronal acetylcholine receptor subunit alpha-7 CHRN alpha C00001429 0 / 0
P10828 Thyroid hormone receptor beta NR1A2 C00008882 3 / 1
P48039 Melatonin receptor type 1A Melatonin receptor C00001429 0 / 0
P13726 Tissue factor Membrane receptor C00029354 0 / 0
P18054 Arachidonate 12-lipoxygenase, 12S-type Enzyme C00001071 2 / 0
Q96RI1 Bile acid receptor NR1H4 C00004565 0 / 0
P23415 Glycine receptor subunit alpha-1 GLR alpha C00001429 1 / 1
P41597 C-C chemokine receptor type 2 CC chemokine receptor C00001179 1 / 0
P28907 ADP-ribosyl cyclase 1 Enzyme C00001071 0 / 1
P10696 Alkaline phosphatase, placental-like Enzyme C00001071 0 / 1
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme C00001179 2 / 1
P56817 Beta-secretase 1 A1A C00008882 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00001071 0 / 0
P09237 Matrilysin M10A C00008882 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00001179 2 / 2
P08253 72 kDa type IV collagenase M10A C00008882 1 / 3
Q9UGH3 Solute carrier family 23 member 2 Ascorbate C00001179 0 / 0
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00004565 2 / 0
Q92887 Canalicular multispecific organic anion transporter 1 Unclassified protein C00001071 1 / 1
P52209 6-phosphogluconate dehydrogenase, decarboxylating Enzyme C00008882 0 / 0
Q01453 Peripheral myelin protein 22 Unclassified protein C00001071 5 / 2
P04406 Glyceraldehyde-3-phosphate dehydrogenase Enzyme C00002647 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00005548 0 / 0
P06133 UDP-glucuronosyltransferase 2B4 Enzyme C00001429 0 / 0
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A C00001179 0 / 0
P00374 Dihydrofolate reductase Oxidoreductase C00008882 1 / 1
P27361 Mitogen-activated protein kinase 3 Erk C00001179 0 / 0
P08588 Beta-1 adrenergic receptor Adrenergic receptor C00001179 1 / 0
P12821 Angiotensin-converting enzyme M2 C00002647 4 / 2
P17252 Protein kinase C alpha type Alpha C00001179 0 / 0
P29466 Caspase-1 C14 C00001179 0 / 0
P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Enzyme C00001071 9 / 1
P35372 Mu-type opioid receptor Opioid receptor C00001179 0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00001179 0 / 0
P25103 Substance-P receptor Neurokinin receptor C00001179 0 / 0
P25105 Platelet-activating factor receptor PAF receptor C00001179 0 / 0
P26358 DNA (cytosine-5)-methyltransferase 1 Transferase C00008882 2 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor C00001179 0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00008882 0 / 0
Q02880 DNA topoisomerase 2-beta Isomerase C00001071 0 / 0
P49286 Melatonin receptor type 1B Melatonin receptor C00001429 0 / 1
P11387 DNA topoisomerase 1 Isomerase C00001071 0 / 0
P16109 P-selectin Adhesion C00002647 1 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00008882 1 / 1
P37059 Estradiol 17-beta-dehydrogenase 2 Enzyme C00004565 0 / 0
P04746 Pancreatic alpha-amylase Hydrolase C00001179 0 / 0
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 C00001179 0 / 0
P98170 E3 ubiquitin-protein ligase XIAP Other cytosolic protein C00004565 1 / 1
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor C00001179 0 / 0
Q15046 Lysine--tRNA ligase Enzyme C00001071 2 / 1
Q13093 Platelet-activating factor acetylhydrolase Enzyme C00002647 3 / 0
Q13639 5-hydroxytryptamine receptor 4 Serotonin receptor C00001429 0 / 0
P27338 Amine oxidase [flavin-containing] B Oxidoreductase C00031437 0 / 0
Q7Z2W7 Transient receptor potential cation channel subfamily M member 8 Unclassified protein C00001429 0 / 0
Q99549 M-phase phosphoprotein 8 Unclassified protein C00001071 0 / 0
P19224 UDP-glucuronosyltransferase 1-6 Enzyme C00001429 0 / 0
P14618 Pyruvate kinase PKM Enzyme C00008882 0 / 0
P08908 5-hydroxytryptamine receptor 1A Serotonin receptor C00001429 1 / 0
P10275 Androgen receptor NR3C4 C00004565 3 / 4
P23975 Sodium-dependent noradrenaline transporter Norepinephrine C00001179 1 / 1
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00001179 0 / 0
P28221 5-hydroxytryptamine receptor 1D Serotonin receptor C00001429 0 / 0
P30542 Adenosine receptor A1 Adenosine receptor C00001179 0 / 0
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00004565 0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00001179 0 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 C00001179 1 / 1
P30939 5-hydroxytryptamine receptor 1F Serotonin receptor C00001429 0 / 0
O95342 Bile salt export pump drug C00008882 2 / 1
P06239 Tyrosine-protein kinase Lck Src C00001179 0 / 1
O15244 Solute carrier family 22 member 2 Drug uniporter C00001429 0 / 0
P35869 Aryl hydrocarbon receptor Transcription Factor C00004565 0 / 0
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor C00001179 0 / 0
P48147 Prolyl endopeptidase S9A C00004565 0 / 0
Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A CMGC dual-specificity kinase DYRK1 C00008882 1 / 0
O14746 Telomerase reverse transcriptase Enzyme C00008882 5 / 5
P31941 DNA dC->dU-editing enzyme APOBEC-3A Enzyme C00001071 0 / 0
P10415 Apoptosis regulator Bcl-2 Other cytosolic protein C00008882 0 / 7
Q16637 Survival motor neuron protein Unclassified protein C00002647 4 / 1
Q9NPH5 NADPH oxidase 4 Enzyme C00004565 0 / 0
Q9H6Z9 Egl nine homolog 3 Enzyme C00001179 0 / 0
P40225 Thrombopoietin Unclassified protein C00001071 1 / 1
O75795 UDP-glucuronosyltransferase 2B17 Enzyme C00001429 1 / 0
Q9P1W9 Serine/threonine-protein kinase pim-2 Pim C00005374 0 / 0
P14061 Estradiol 17-beta-dehydrogenase 1 Enzyme C00004565 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00001071 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00001071 1 / 4
Q9UN88 Gamma-aminobutyric acid receptor subunit theta GABA-A theta C00001429 0 / 0
P28472 Gamma-aminobutyric acid receptor subunit beta-3 GABA-A beta C00001429 1 / 0
P14867 Gamma-aminobutyric acid receptor subunit alpha-1 GABA-A alpha C00001429 1 / 1
P48169 Gamma-aminobutyric acid receptor subunit alpha-4 GABA-A alpha C00001429 0 / 0
O14764 Gamma-aminobutyric acid receptor subunit delta GABA-A delta C00001429 1 / 1
P31644 Gamma-aminobutyric acid receptor subunit alpha-5 GABA-A alpha C00001429 0 / 0
Q99928 Gamma-aminobutyric acid receptor subunit gamma-3 GABA-A gamma C00001429 0 / 0
P78334 Gamma-aminobutyric acid receptor subunit epsilon GABA-A epsilon C00001429 0 / 0
Q8N1C3 Gamma-aminobutyric acid receptor subunit gamma-1 GABA-A gamma C00001429 0 / 0
P34903 Gamma-aminobutyric acid receptor subunit alpha-3 GABA-A alpha C00001429 0 / 0
O00591 Gamma-aminobutyric acid receptor subunit pi GABA-A pi C00001429 0 / 0
P47870 Gamma-aminobutyric acid receptor subunit beta-2 GABA-A beta C00001429 0 / 0
P18507 Gamma-aminobutyric acid receptor subunit gamma-2 GABA-A gamma C00001429 4 / 2
P18505 Gamma-aminobutyric acid receptor subunit beta-1 GABA-A beta C00001429 0 / 0
Q16445 Gamma-aminobutyric acid receptor subunit alpha-6 GABA-A alpha C00001429 0 / 0
P47869 Gamma-aminobutyric acid receptor subunit alpha-2 GABA-A alpha C00001429 1 / 0
O75751 Solute carrier family 22 member 3 Unclassified protein C00001429 0 / 0
O95067 G2/mitotic-specific cyclin-B2 Other cytosolic protein C00004565 0 / 0
P14635 G2/mitotic-specific cyclin-B1 Other cytosolic protein C00004565 0 / 0
P06493 Cyclin-dependent kinase 1 Cdc2 C00004565 0 / 0
Q8WWL7 G2/mitotic-specific cyclin-B3 Other cytosolic protein C00004565 0 / 0
Q8WXA8 5-hydroxytryptamine receptor 3C NS C00001429 0 / 0
Q70Z44 5-hydroxytryptamine receptor 3D NS C00001429 0 / 0
O95264 5-hydroxytryptamine receptor 3B NS C00001429 0 / 0
A5X5Y0 5-hydroxytryptamine receptor 3E NS C00001429 0 / 0
P49840 Glycogen synthase kinase-3 alpha Gsk C00004565 0 / 0
P42345 Serine/threonine-protein kinase mTOR Enzyme C00001071 0 / 0
Q9H0H5 Rac GTPase-activating protein 1 Unclassified protein C00004565 0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00001071 2 / 1
Q9HCT0 Fibroblast growth factor 22 Unclassified protein C00001071 0 / 0

389 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00001071 C00001179 C00001429 C00002647
C00004565
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00001071 C00001179 C00002647 C00004565
C00007247
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001071 C00001179 C00004565 C00004635
C00005374
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00001071 C00004565 C00004635 C00005374
4363 ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 C00001071 C00001179 C00004565 C00004635
5243 ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) C00001179 C00002647 C00004565 C00004635
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00001071 C00001179 C00002647 C00004565
581 BAX, BCL2L4 BCL2-associated X protein C00001071 C00001179 C00002647 C00004565
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00001179 C00001429 C00004565 C00007247
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00001071 C00001179 C00002647 C00004565
3569 IL6, BSF2, HGF, HSF, IFNB2, IL-6 interleukin 6 (interferon, beta 2) C00001071 C00001429 C00002647 C00004565
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00001071 C00001179 C00002647 C00004565
4233 MET, AUTS9, HGFR, RCCP2, c-Met met proto-oncogene (EC:2.7.10.1) C00001071 C00001179 C00004565
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) C00001071 C00001179 C00001429
6817 SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) C00001179 C00001429 C00002647
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00001071 C00001179 C00007247
847 CAT catalase (EC:1.11.1.6) C00001071 C00001179 C00001429
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00001179 C00001429 C00002647
1080 CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1 cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) C00001179 C00001429 C00004565
4780 NFE2L2, NRF2 nuclear factor, erythroid 2-like 2 C00001071 C00001179 C00004565
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00001179 C00002647 C00004565
54205 CYCS, CYC, HCS, THC4 cytochrome c, somatic C00001071 C00002647 C00004565
2729 GCLC, GCL, GCS, GLCL, GLCLC glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) C00004565 C00007247
4316 MMP7, MMP-7, MPSL1, PUMP-1 matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23) C00001179 C00002647
1401 CRP, PTX1 C-reactive protein, pentraxin-related C00001179 C00004565
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00004565 C00007247
1147 CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16 conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) C00002647 C00004565
1559 CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) C00004565 C00007247
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00004565 C00007247
5599 MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c mitogen-activated protein kinase 8 (EC:2.7.11.24) C00001179 C00002647
2099 ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 estrogen receptor 1 C00004565 C00004635
2100 ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 estrogen receptor 2 (ER beta) C00004565 C00004635
2203 FBP1, FBP fructose-1,6-bisphosphatase 1 (EC:3.1.3.11) C00001071 C00004565
1031 CDKN2C, INK4C, p18, p18-INK4C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) C00001071 C00004565
1571 CYP2E1, CPE1, CYP2E, P450-J, P450C2E cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) C00001179 C00007247
5601 MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK mitogen-activated protein kinase 9 (EC:2.7.11.24) C00001179 C00002647
338 APOB, FLDB, LDLCQ4 apolipoprotein B C00001179 C00002647
2938 GSTA1, GST2, GSTA1-1, GTH1 glutathione S-transferase alpha 1 (EC:2.5.1.18) C00001179 C00004565
4973 OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1 oxidized low density lipoprotein (lectin-like) receptor 1 C00001179 C00004635
3014 H2AFX, H2A.X, H2A/X, H2AX H2A histone family, member X C00001179 C00004565
4846 NOS3, ECNOS, eNOS nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) C00001179 C00004635
3082 HGF, DFNB39, F-TCF, HGFB, HPTA, SF hepatocyte growth factor (hepapoietin A; scatter factor) C00001071 C00004565
3383 ICAM1, BB2, CD54, P3.58 intercellular adhesion molecule 1 C00001179 C00004565
4353 MPO myeloperoxidase (EC:1.11.2.2) C00001179 C00001429
3565 IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4 interleukin 4 C00004565 C00007247
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00001071 C00002647
891 CCNB1, CCNB cyclin B1 C00001071 C00004565
5879 RAC1, Rac-1, TC-25, p21-Rac1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) C00001179 C00002647
4318 MMP9, CLG4B, GELB, MANDP2, MMP-9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) C00001071 C00002647
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00002647 C00004565
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00002647 C00004565
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00001071 C00004565
27113 BBC3, JFY-1, JFY1, PUMA BCL2 binding component 3 C00001179 C00004565
3091 HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) C00001071 C00001179
472 ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1 ataxia telangiectasia mutated (EC:2.7.11.1) C00002647 C00004565
397 ARHGDIB, D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2 Rho GDP dissociation inhibitor (GDI) beta C00001071 C00001179
6818 SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1) C00001179 C00001429
1244 ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP ATP-binding cassette, sub-family C (CFTR/MRP), member 2 C00001071 C00001179
4843 NOS2, HEP-NOS, INOS, NOS, NOS2A nitric oxide synthase 2, inducible (EC:1.14.13.39) C00001179 C00004565
54600 UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) C00001179 C00004565
54575 UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) C00001179 C00004565
7161 TP73, P73 tumor protein p73 C00001071 C00004565
10891 PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha C00001179 C00004565
8000 PSCA, PRO232 prostate stem cell antigen C00001071 C00004565
7224 TRPC5, TRP5 transient receptor potential cation channel, subfamily C, member 5 C00001179 C00002647
8626 TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L tumor protein p63 C00001071 C00004565
9540 TP53I3, PIG3 tumor protein p53 inducible protein 3 C00001071 C00004565
6513 SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED solute carrier family 2 (facilitated glucose transporter), member 1 C00001071 C00004565
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00002647 C00004565
196 AHR, bHLHe76 aryl hydrocarbon receptor C00004565 C00004635
7031 TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 trefoil factor 1 C00004565 C00004635
3551 IKBKB, IKK-beta, IKK2, IKKB, NFKBIKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) C00002647
7019 TFAM, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3 transcription factor A, mitochondrial C00004565
6773 STAT2, ISGF-3, P113, STAT113 signal transducer and activator of transcription 2, 113kDa C00004565
2810 SFN, YWHAS stratifin C00004565
6119 RPA3, REPA3 replication protein A3, 14kDa C00004565
5241 PGR, NR3C3, PR progesterone receptor C00004565
7352 UCP3, SLC25A9 uncoupling protein 3 (mitochondrial, proton carrier) C00004565
54658 UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) C00004565
9970 NR1I3, CAR, CAR1, MB67 nuclear receptor subfamily 1, group I, member 3 C00004565
54659 UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) C00004565
54577 UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) C00004565
54576 UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) C00004565
8856 NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR nuclear receptor subfamily 1, group I, member 2 C00004565
7402 UTRN, DMDL, DRP, DRP1 utrophin C00004565
8839 WISP2, CCN5, CT58, CTGF-L WNT1 inducible signaling pathway protein 2 C00004565
4792 NFKBIA, IKBA, MAD-3, NFKBI nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha C00004565
8202 NCOA3, ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP nuclear receptor coactivator 3 (EC:2.3.1.48) C00004565
4586 MUC5AC, MUC5, TBM, leB mucin 5AC, oligomeric mucus/gel-forming C00004565
1312 COMT catechol-O-methyltransferase (EC:2.1.1.6) C00001071
1499 CTNNB1, CTNNB, MRD19, armadillo catenin (cadherin-associated protein), beta 1, 88kDa C00001071
1786 DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37) C00001071
54583 EGLN1, C1orf12, ECYT3, HIF-PH2, HIFPH2, HPH-2, HPH2, PHD2, SM20, ZMYND6 egl-9 family hypoxia-inducible factor 1 (EC:1.14.11.29) C00001071
4502 MT2A, MT2 metallothionein 2A C00004565
110357 C00004565
4297 KMT2A, ALL-1, CXXC7, HRX, HTRX1, MLL, MLL/GAS7, MLL1A, TET1-MLL, TRX1, WDSTS lysine (K)-specific methyltransferase 2A (EC:2.1.1.43) C00004565
4609 MYC, MRTL, MYCC, bHLHe39, c-Myc v-myc avian myelocytomatosis viral oncogene homolog C00001071
8505 PARG, PARG99 poly (ADP-ribose) glycohydrolase (EC:3.2.1.143) C00001071
3725 JUN, AP-1, AP1, c-Jun jun proto-oncogene C00004565
3567 IL5, EDF, IL-5, TRF interleukin 5 (colony-stimulating factor, eosinophil) C00004565
23411 SIRT1, SIR2L1 sirtuin 1 C00001071
7153 TOP2A, TOP2, TP2A topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) C00001071
3043 HBB, CD113t-C, beta-globin hemoglobin, beta C00004565
2950 GSTP1, DFN7, FAEES3, GST3, GSTP, PI glutathione S-transferase pi 1 (EC:2.5.1.18) C00004565
16 AARS, CMT2N alanyl-tRNA synthetase (EC:6.1.1.7) C00001179
19 ABCA1, ABC-1, ABC1, CERP, HDLDT1, TGD ATP-binding cassette, sub-family A (ABC1), member 1 C00001179
59272 ACE2, ACEH angiotensin I converting enzyme 2 (EC:3.4.17.23) C00001179
59 ACTA2, AAT6, ACTSA, MYMY5 actin, alpha 2, smooth muscle, aorta C00001179
112 ADCY6, AC6 adenylate cyclase 6 (EC:4.6.1.1) C00001179
231 AKR1B1, ADR, ALDR1, ALR2, AR aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21) C00001179
248 ALPI, IAP alkaline phosphatase, intestinal (EC:3.1.3.1) C00001179
290 ANPEP, APN, CD13, GP150, LAP1, P150, PEPN alanyl (membrane) aminopeptidase (EC:3.4.11.2) C00001179
301 ANXA1, ANX1, LPC1 annexin A1 C00001179
335 APOA1 apolipoprotein A-I C00001179
9687 GREB1 growth regulation by estrogen in breast cancer 1 C00004565
55937 APOM, G3a, HSPC336, NG20, apo-M apolipoprotein M C00001179
351 APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2 amyloid beta (A4) precursor protein C00001179
360 AQP3, AQP-3, GIL aquaporin 3 (Gill blood group) C00001179
440 ASNS, TS11 asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4) C00001179
467 ATF3 activating transcription factor 3 C00001179
9212 AURKB, AIK2, AIM-1, AIM1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5, aurkb-sv1, aurkb-sv2 aurora kinase B (EC:2.7.11.1) C00001179
79370 BCL2L14, BCLG BCL2-like 14 (apoptosis facilitator) C00001179
632 BGLAP, BGP, OC, OCN bone gamma-carboxyglutamate (gla) protein C00001179
12095 C00001179
330 BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 baculoviral IAP repeat containing 3 C00001179
332 BIRC5, API4, EPR-1 baculoviral IAP repeat containing 5 C00001179
699 BUB1, BUB1A, BUB1L, hBUB1 BUB1 mitotic checkpoint serine/threonine kinase (EC:2.7.11.1) C00001179
768 CA9, CAIX, MN carbonic anhydrase IX (EC:4.2.1.1) C00001179
840 CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) C00001179
875 CBS, HIP4 cystathionine-beta-synthase (EC:4.2.1.22) C00001179
6347 CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF chemokine (C-C motif) ligand 2 C00001179
595 CCND1, BCL1, D11S287E, PRAD1, U21B31 cyclin D1 C00001179
894 CCND2, KIAK0002 cyclin D2 C00001179
100133941 CD24, CD24A CD24 molecule C00001179
947 CD34 CD34 molecule C00001179
958 CD40, Bp50, CDW40, TNFRSF5, p50 CD40 molecule, TNF receptor superfamily member 5 C00001179
990 CDC6, CDC18L, HsCDC18, HsCDC6 cell division cycle 6 C00001179
728642 CDK11A, CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, PITSLRE, p58GTA cyclin-dependent kinase 11A (EC:2.7.11.22) C00001179
629 CFB, AHUS4, BF, BFD, CFAB, FB, FBI12, GBG, H2-Bf, PBF2 complement factor B (EC:3.4.21.47) C00001179
11113 CIT, CRIK, STK21 citron (rho-interacting, serine/threonine kinase 21) (EC:2.7.11.1) C00001179
1264 CNN1, SMCC, Sm-Calp calponin 1, basic, smooth muscle C00001179
1270 CNTF, HCNTF ciliary neurotrophic factor C00001179
1277 COL1A1, OI4 collagen, type I, alpha 1 C00001179
1380 CR2, C3DR, CD21, CR, CVID7, SLEB9 complement component (3d/Epstein Barr virus) receptor 2 C00001179
1519 CTSO, CTSO1 cathepsin O (EC:3.4.22.42) C00001179
3627 CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1 chemokine (C-X-C motif) ligand 10 C00001179
6372 CXCL6, CKA-3, GCP-2, GCP2, SCYB6 chemokine (C-X-C motif) ligand 6 C00001179
4283 CXCL9, CMK, Humig, MIG, SCYB9, crg-10 chemokine (C-X-C motif) ligand 9 C00001179
643 CXCR5, BLR1, CD185, MDR15 chemokine (C-X-C motif) receptor 5 C00001179
79901 CYBRD1, CYB561A2, DCYTB, FRRS3 cytochrome b reductase 1 C00001179
1583 CYP11A1, CYP11A, CYPXIA1, P450SCC cytochrome P450, family 11, subfamily A, polypeptide 1 (EC:1.14.15.6) C00001179
1588 CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001179
1548 CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) C00001179
1556 CYP2B7P, CYP2B, CYP2B7, CYP2B7P1 cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene C00001179
4616 GADD45B, GADD45BETA, MYD118 growth arrest and DNA-damage-inducible, beta C00004565
22943 DKK1, DKK-1, SK dickkopf WNT signaling pathway inhibitor 1 C00001179
9787 DLGAP5, DLG7, HURP discs, large (Drosophila) homolog-associated protein 5 C00001179
54431 DNAJC10, ERdj5, JPDI, MTHr, PDIA19 DnaJ (Hsp40) homolog, subfamily C, member 10 C00001179
1773 DNASE1, DNL1, DRNI deoxyribonuclease I (EC:3.1.21.1) C00001179
1803 DPP4, ADABP, ADCP2, CD26, DPPIV, TP103 dipeptidyl-peptidase 4 (EC:3.4.14.5) C00001179
1906 EDN1, ET1, HDLCQ7, PPET1 endothelin 1 C00001179
1908 EDN3, ET-3, ET3, HSCR4, PPET3, WS4B endothelin 3 C00001179
1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA epidermal growth factor receptor (EC:2.7.10.1) C00001179
112399 EGLN3, HIFP4H3, HIFPH3, PHD3 egl-9 family hypoxia-inducible factor 3 (EC:1.14.11.29) C00001179
8894 EIF2S2, EIF2, EIF2B, EIF2beta, PPP1R67, eIF-2-beta eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa C00001179
8661 EIF3A, EIF3, EIF3S10, P167, TIF32, eIF3-p170, eIF3-theta, p180, p185 eukaryotic translation initiation factor 3, subunit A C00001179
8343525 C00001179
1973 EIF4A1, DDX2A, EIF-4A, EIF4A, eIF-4A-I, eIF4A-I eukaryotic translation initiation factor 4A1 (EC:3.6.4.13) C00001179
2012 EMP1, CL-20, EMP-1, TMP epithelial membrane protein 1 C00001179
2014 EMP3, YMP epithelial membrane protein 3 C00001179
2034 EPAS1, ECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73 endothelial PAS domain protein 1 C00001179
2052 EPHX1, EPHX, EPOX, HYL1, MEH epoxide hydrolase 1, microsomal (xenobiotic) (EC:3.3.2.9) C00001179
2053 EPHX2, CEH, SEH epoxide hydrolase 2, cytoplasmic (EC:3.3.2.10 3.1.3.76) C00001179
2058 EPRS, EARS, GLUPRORS, PARS, QARS, QPRS glutamyl-prolyl-tRNA synthetase (EC:6.1.1.15 6.1.1.17) C00001179
2172 FABP6, I-15P, I-BABP, I-BALB, I-BAP, ILBP, ILBP3, ILLBP fatty acid binding protein 6, ileal C00001179
2321 FLT1, FLT, FLT-1, VEGFR-1, VEGFR1 fms-related tyrosine kinase 1 (EC:2.7.10.1) C00001179
2326 FMO1 flavin containing monooxygenase 1 (EC:1.14.13.8) C00001179
2330 FMO5 flavin containing monooxygenase 5 (EC:1.14.13.8) C00001179
2335 FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF fibronectin 1 C00001179
2302 FOXJ1, FKHL13, HFH-4, HFH4 forkhead box J1 C00001179
2534 FYN, SLK, SYN, p59-FYN FYN oncogene related to SRC, FGR, YES (EC:2.7.10.2) C00001179
2535 FZD2, Fz2, fz-2, fzE2, hFz2 frizzled family receptor 2 C00001179
50486 G0S2, RP1-28O10.2 G0/G1switch 2 C00001179
2580 GAK, DNAJ26, DNAJC26 cyclin G associated kinase (EC:2.7.11.1) C00001179
2617 GARS, CMT2D, DSMAV, GlyRS, HMN5, SMAD1 glycyl-tRNA synthetase (EC:6.1.1.14) C00001179
2623 GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT GATA binding protein 1 (globin transcription factor 1) C00001179
2674 GFRA1, GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1 GDNF family receptor alpha 1 C00001179
2744 GLS, AAD20, GAC, GAM, GLS1, KGA glutaminase (EC:3.5.1.2) C00001179
2876 GPX1, GPXD, GSHPX1 glutathione peroxidase 1 (EC:1.11.1.9) C00001179
2877 GPX2, GI-GPx, GPRP, GPRP-2, GPx-2, GPx-GI, GSHPX-GI, GSHPx-2 glutathione peroxidase 2 (gastrointestinal) (EC:1.11.1.9) C00001179
2936 GSR glutathione reductase (EC:1.8.1.7) C00001179
2944 GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1 glutathione S-transferase mu 1 (EC:2.5.1.18) C00001179
2952 GSTT1 glutathione S-transferase theta 1 (EC:2.5.1.18) C00001179
2965 GTF2H1, BTF2, P62, TFB1, TFIIH general transcription factor IIH, polypeptide 1, 62kDa C00001179
9843 HEPH, CPL hephaestin C00001179
9709 HERPUD1, HERP, Mif1, SUP homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 C00001179
3098 HK1, HK1-ta, HK1-tb, HK1-tc, HKD, HKI, HMSNR, HXK1 hexokinase 1 (EC:2.7.1.1) C00001179
3240 HP, BP, HP2ALPHA2, HPA1S haptoglobin C00001179
3283 HSD3B1, 3BETAHSD, HSD3B, HSDB3, HSDB3A, I, SDR11E1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (EC:1.1.1.145 5.3.3.1) C00001179
3303 HSPA1A, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1 heat shock 70kDa protein 1A C00001179
3309 HSPA5, BIP, GRP78, MIF2 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) C00001179
3313 HSPA9, CSA, GRP-75, GRP75, HSPA9B, MOT, MOT2, MTHSP75, PBP74 heat shock 70kDa protein 9 (mortalin) C00001179
3315 HSPB1, CMT2F, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27 heat shock 27kDa protein 1 C00001179
3347 HTN3, HIS2, HTN2, HTN5 histatin 3 C00001179
3376 IARS, IARS1, ILERS, ILRS, IRS, PRO0785 isoleucyl-tRNA synthetase (EC:6.1.1.5) C00001179
8870 IER3, DIF-2, DIF2, GLY96, IEX-1, IEX-1L, IEX1, PRG1 immediate early response 3 C00001179
3488 IGFBP5, IBP5 insulin-like growth factor binding protein 5 C00001179
10320 IKZF1, Hs.54452, IK1, IKAROS, LYF1, PRO0758, ZNFN1A1, hIk-1 IKAROS family zinc finger 1 (Ikaros) C00001179
2353 FOS, AP-1, C-FOS, p55 FBJ murine osteosarcoma viral oncogene homolog C00004565
3745 KCNB1, DRK1, KV2.1, h-DRK1 potassium voltage-gated channel, Shab-related subfamily, member 1 C00001179
3791 KDR, CD309, FLK1, VEGFR, VEGFR2 kinase insert domain receptor (a type III receptor tyrosine kinase) (EC:2.7.10.1) C00001179
9493 KIF23, CHO1, KNSL5, MKLP-1, MKLP1 kinesin family member 23 C00001179
3932 LCK, LSK, YT16, p56lck, pp58lck lymphocyte-specific protein tyrosine kinase (EC:2.7.10.2) C00001179
3956 LGALS1, GAL1, GBP lectin, galactoside-binding, soluble, 1 C00001179
4017 LOXL2, LOR2, WS9-14 lysyl oxidase-like 2 (EC:1.4.3.-) C00001179
4067 LYN, JTK8, p53Lyn, p56Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (EC:2.7.10.2) C00001179
23764 MAFF, U-MAF, hMafF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F C00001179
10892 MALT1, IMD12, MLT, MLT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 (EC:3.4.22.-) C00001179
5606 MAP2K3, MAPKK3, MEK3, MKK3, PRKMK3, SAPKK-2, SAPKK2 mitogen-activated protein kinase kinase 3 (EC:2.7.12.2) C00001179
5608 MAP2K6, MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3 mitogen-activated protein kinase kinase 6 (EC:2.7.12.2) C00001179
4217 MAP3K5, ASK1, MAPKKK5, MEKK5 mitogen-activated protein kinase kinase kinase 5 (EC:2.7.11.25) C00001179
1432 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA mitogen-activated protein kinase 14 (EC:2.7.11.24) C00001179
1734 DIO2, 5DII, D2, DIOII, SelY, TXDI2 deiodinase, iodothyronine, type II (EC:1.97.1.10) C00004565
37618 C00004565
4173 MCM4, CDC21, CDC54, NKCD, NKGCD, P1-CDC21, hCdc21 minichromosome maintenance complex component 4 (EC:3.6.4.12) C00001179
4224 MEP1A, PPHA meprin A, alpha (PABA peptide hydrolase) (EC:3.4.24.18) C00001179
4288 MKI67, KIA, MIB-1 marker of proliferation Ki-67 C00001179
4292 MLH1, COCA2, FCC2, HNPCC, HNPCC2, hMLH1 mutL homolog 1 C00001179
4312 MMP1, CLG, CLGN matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) C00001179
1437 CSF2, GMCSF colony stimulating factor 2 (granulocyte-macrophage) C00004565
983 CDK1, CDC2, CDC28A, P34CDC2 cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) C00004565
4436 MSH2, COCA1, FCC1, HNPCC, HNPCC1, LCFS2 mutS homolog 2 C00001179
4485 MST1, D3F15S2, DNF15S2, HGFL, MSP, NF15S2 macrophage stimulating 1 (hepatocyte growth factor-like) C00001179
11223 MST1L, BRF-1, D1F15S1A, MSPL-7, MSPL7, MST1P9, MSTP7, MSTP9 macrophage stimulating 1-like C00001179
4504 MT3, GIF, GIFB, GRIF, ZnMT3 metallothionein 3 C00001179
10797 MTHFD2, NMDMC methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (EC:3.5.4.9 1.5.1.15) C00001179
4605 MYBL2, B-MYB, BMYB v-myb avian myeloblastosis viral oncogene homolog-like 2 C00001179
4640 MYO1A, BBMI, DFNA48, MIHC, MYHL myosin IA C00001179
4677 NARS, ASNRS, NARS1 asparaginyl-tRNA synthetase (EC:6.1.1.22) C00001179
10397 NDRG1, CAP43, CMT4D, DRG-1, DRG1, GC4, HMSNL, NDR1, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5 N-myc downstream regulated 1 C00001179
4800 NFYA, CBF-A, CBF-B, HAP2, NF-YA nuclear transcription factor Y, alpha C00001179
4814 NINJ1, NIN1, NINJURIN ninjurin 1 C00001179
7080 NKX2-1, BCH, BHC, NK-2, NKX2.1, NKX2A, TEBP, TITF1, TTF-1, TTF1 NK2 homeobox 1 C00001179
4830 NME1, AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1 NME/NM23 nucleoside diphosphate kinase 1 (EC:2.7.4.6) C00001179
2908 NR3C1, GCCR, GCR, GR, GRL nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) C00001179
8013 NR4A3, CHN, CSMF, MINOR, NOR1, TEC nuclear receptor subfamily 4, group A, member 3 C00001179
10956 OS9, ERLEC2, OS-9 osteosarcoma amplified 9, endoplasmic reticulum lectin C00001179
8974 P4HA2 prolyl 4-hydroxylase, alpha polypeptide II (EC:1.14.11.2) C00001179
54681 P4HTM, EGLN4, HIFPH4, P4H-TM, PH-4, PH4, PHD4 prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) C00001179
5106 PCK2, PEPCK, PEPCK-M, PEPCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) (EC:4.1.1.32) C00001179
64714 PDIA2, PDA2, PDI, PDIP, PDIR protein disulfide isomerase family A, member 2 (EC:5.3.4.1) C00001179
2923 PDIA3, ER60, ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC protein disulfide isomerase family A, member 3 (EC:5.3.4.1) C00001179
26227 PHGDH, 3-PGDH, 3PGDH, PDG, PGAD, PGD, PGDH, SERA phosphoglycerate dehydrogenase (EC:1.1.1.95) C00001179
22822 PHLDA1, DT1P1B11, PHRIP, TDAG51 pleckstrin homology-like domain, family A, member 1 C00001179
7262 PHLDA2, BRW1C, BWR1C, HLDA2, IPL, TSSC3 pleckstrin homology-like domain, family A, member 2 C00001179
11145 PLA2G16, AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-1, HREV107-3, HRSL3 phospholipase A2, group XVI (EC:3.1.1.4 3.1.1.32) C00001179
5340 PLG plasminogen (EC:3.4.21.7) C00001179
5347 PLK1, PLK, STPK13 polo-like kinase 1 (EC:2.7.11.21) C00001179
5366 PMAIP1, APR, NOXA phorbol-12-myristate-13-acetate-induced protein 1 C00001179
5376 PMP22, CMT1A, CMT1E, DSS, GAS-3, HMSNIA, HNPP, Sp110 peripheral myelin protein 22 C00001179
5444 PON1, ESA, MVCD5, PON paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) C00001179
5445 PON2 paraoxonase 2 (EC:3.1.1.2 3.1.1.81) C00001179
5460 POU5F1, OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4 POU class 5 homeobox 1 C00001179
5588 PRKCQ, PRKCT, nPKC-theta protein kinase C, theta (EC:2.7.11.13) C00001179
38175 C00001179
5702 PSMC3, TBP1 proteasome (prosome, macropain) 26S subunit, ATPase, 3 C00001179
5865 RAB3B RAB3B, member RAS oncogene family C00001179
5870 RAB6A, RAB6 RAB6A, member RAS oncogene family C00001179
6352 CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP chemokine (C-C motif) ligand 5 C00004565
5889 RAD51C, BROVCA3, FANCO, R51H3, RAD51L2 RAD51 paralog C C00001179
25788 RAD54B, RDH54 RAD54 homolog B (S. cerevisiae) C00001179
1827 RCAN1, ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1 regulator of calcineurin 1 C00001179
860 RUNX2, AML3, CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, PEA2aA, PEBP2aA runt-related transcription factor 2 C00001179
795 S100G, CABP, CABP1, CABP9K, CALB3 S100 calcium binding protein G C00001179
5055 SERPINB2, HsT1201, PAI, PAI-2, PAI2, PLANH2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 C00001179
83667 SESN2, HI95, SES2, SEST2 sestrin 2 C00001179
6439 SFTPB, PSP-B, SFTB3, SFTP3, SMDP1, SP-B surfactant protein B C00001179
6472 SHMT2, GLYA, SHMT serine hydroxymethyltransferase 2 (mitochondrial) (EC:2.1.2.1) C00001179
6476 SI sucrase-isomaltase (alpha-glucosidase) (EC:3.2.1.10 3.2.1.48) C00001179
4891 SLC11A2, DCT1, DMT1, NRAMP2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 C00001179
10864 SLC22A7, NLT, OAT2 solute carrier family 22 (organic anion transporter), member 7 C00001179
9963 SLC23A1, SLC23A2, SVCT1, YSPL3 solute carrier family 23 (ascorbic acid transporter), member 1 C00001179
9962 SLC23A2, NBTL1, SLC23A1, SVCT2, YSPL2 solute carrier family 23 (ascorbic acid transporter), member 2 C00001179
79677 SMC6, SMC-6, SMC6L1, hSMC6 structural maintenance of chromosomes 6 C00001179
6647 SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer superoxide dismutase 1, soluble (EC:1.15.1.1) C00001179
6648 SOD2, IPOB, MNSOD, MVCD6 superoxide dismutase 2, mitochondrial (EC:1.15.1.1) C00001179
6657 SOX2, ANOP3, MCOPS3 SRY (sex determining region Y)-box 2 C00001179
6667 SP1 Sp1 transcription factor C00001179
6670 SP3, SPR2 Sp3 transcription factor C00001179
6671 SP4, HF1B, SPR-1 Sp4 transcription factor C00001179
6678 SPARC, ON secreted protein, acidic, cysteine-rich (osteonectin) C00001179
6696 SPP1, BNSP, BSPI, ETA-1, OPN secreted phosphoprotein 1 C00001179
6772 STAT1, CANDF7, ISGF-3, STAT91 signal transducer and activator of transcription 1, 91kDa C00001179
6774 STAT3, APRF, HIES signal transducer and activator of transcription 3 (acute-phase response factor) C00001179
9262 STK17B, DRAK2 serine/threonine kinase 17b (EC:2.7.11.1) C00001179
598 BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS BCL2-like 1 C00004565
405 ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 aryl hydrocarbon receptor nuclear translocator C00004565
20888 C00001179
6822 SULT2A1, DHEA-ST, DHEAS, HST, ST2, ST2A1, ST2A3, STD, hSTa sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 (EC:2.8.2.14) C00001179
6876 TAGLN, SM22, SMCC, TAGLN1, WS3-10 transgelin C00001179
6897 TARS, ThrRS threonyl-tRNA synthetase (EC:6.1.1.3) C00001179
6901 TAZ, BTHS, CMD3A, EFE, EFE2, G4.5, LVNCX, Taz1 tafazzin C00001179
7018 TF, PRO1557, PRO2086, TFQTL1 transferrin C00001179
7032 TFF2, SML1, SP trefoil factor 2 C00001179
7040 TGFB1, CED, DPD1, LAP, TGFB, TGFbeta transforming growth factor, beta 1 C00001179
7076 TIMP1, CLGI, EPA, EPO, HCI, TIMP TIMP metallopeptidase inhibitor 1 C00001179
4071 TM4SF1, H-L6, L6, M3S1, TAAL6 transmembrane 4 L six family member 1 C00001179
164656 TMPRSS6, IRIDA transmembrane protease, serine 6 C00001179
4982 TNFRSF11B, OCIF, OPG, TR1 tumor necrosis factor receptor superfamily, member 11b C00001179
8743 TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL tumor necrosis factor (ligand) superfamily, member 10 C00001179
11257 TP53TG1, LINC00096, NCRNA00096, P53TG1, P53TG1-D, TP53AP1 TP53 target 1 (non-protein coding) C00001179
57761 TRIB3, C20orf97, NIPK, SINK, SKIP3, TRB3 tribbles pseudokinase 3 C00001179
9322 TRIP10, CIP4, HSTP, STOT, STP thyroid hormone receptor interactor 10 C00001179
239 ALOX12, 12-LOX, 12S-LOX, LOG12 arachidonate 12-lipoxygenase (EC:1.13.11.31) C00004565
7299 TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 tyrosinase (EC:1.14.18.1) C00001179
7319 UBE2A, HHR6A, MRXS30, MRXSN, RAD6A, UBC2 ubiquitin-conjugating enzyme E2A (EC:6.3.2.19) C00001179
7366 UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) C00001179
7412 VCAM1, CD106, INCAM-100 vascular cell adhesion molecule 1 C00001179
7428 VHL, HRCA1, RCA1, VHL1, pVHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase C00001179
55350 VNN3, HSA238982 vanin 3 C00001179
7443 VRK1, PCH1, PCH1A vaccinia related kinase 1 (EC:2.7.11.1) C00001179
7453 WARS, GAMMA-2, IFI53, IFP53 tryptophanyl-tRNA synthetase (EC:6.1.1.2) C00001179
10352 WARS2, TrpRS tryptophanyl tRNA synthetase 2, mitochondrial (EC:6.1.1.2) C00001179
25937 WWTR1, TAZ WW domain containing transcription regulator 1 C00001179
7512 XPNPEP2, APP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound (EC:3.4.11.9) C00001179
7515 XRCC1, RCC X-ray repair complementing defective repair in Chinese hamster cells 1 C00001179
7718 ZNF165, CT53, LD65, ZSCAN7 zinc finger protein 165 C00001179
25 ABL1, ABL, JTK7, bcr/abl, c-ABL, p150, v-abl c-abl oncogene 1, non-receptor tyrosine kinase (EC:2.7.10.2) C00002647
545 ATR, FCTCS, FRP1, MEC1, SCKL, SCKL1 ataxia telangiectasia and Rad3 related (EC:2.7.11.1) C00002647
613 BCR, ALL, BCR1, CML, D22S11, D22S662, PHL breakpoint cluster region (EC:2.7.11.1) C00002647
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00002647
898 CCNE1, CCNE cyclin E1 C00002647
998 CDC42, CDC42Hs, G25K cell division cycle 42 C00002647
1027 CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 cyclin-dependent kinase inhibitor 1B (p27, Kip1) C00002647
7852 CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM chemokine (C-X-C motif) receptor 4 C00002647
356 FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 Fas ligand (TNF superfamily, member 6) C00002647
2551 GABPA, E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A, RCH04A07 GA binding protein transcription factor, alpha subunit 60kDa C00002647
2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2 growth factor receptor-bound protein 2 C00002647
7039 TGFA, TFGA transforming growth factor, alpha C00004565
3949 LDLR, FH, FHC, LDLCQ2 low density lipoprotein receptor C00002647
5604 MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1 mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) C00002647
4255 MGMT O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63) C00002647
4313 MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) C00002647
4793 NFKBIB, IKBB, TRIP9 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta C00002647
5578 PRKCA, AAG6, PKC-alpha, PKCA, PRKACA protein kinase C, alpha (EC:2.7.11.13) C00002647
5591 PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350 protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1) C00002647
19412 C00002647
387 RHOA, ARH12, ARHA, RHO12, RHOH12 ras homolog family member A C00002647
388 RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6 ras homolog family member B C00002647
6195 RPS6KA1, HU-1, MAPKAPK1A, RSK, RSK1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1) C00002647
9252 RPS6KA5, MSK1, MSPK1, RLPK ribosomal protein S6 kinase, 90kDa, polypeptide 5 (EC:2.7.11.1) C00002647
6622 SNCA, NACP, PARK1, PARK4, PD1 synuclein, alpha (non A4 component of amyloid precursor) C00002647
7422 VEGFA, MVCD1, VEGF, VPF vascular endothelial growth factor A C00002647
331 XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 X-linked inhibitor of apoptosis C00002647
2597 GAPDH, G3PD, GAPD glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12) C00001429
2932 GSK3B glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) C00001429
3352 HTR1D, 5-HT1D, HT1DA, HTR1DA, HTRL, RDC4 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled C00001429
3356 HTR2A, 5-HT2A, HTR2 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled C00001429
3359 HTR3A, 5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic C00001429
9177 HTR3B, 5-HT3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic C00001429
3363 HTR7, 5-HT7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled C00001429
3593 IL12B, CLMF, CLMF2, IL-12B, NKSF, NKSF2 interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) C00001429
3690 ITGB3, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) C00001429
4128 MAOA, MAO-A monoamine oxidase A (EC:1.4.3.4) C00001429
6570 SLC18A1, CGAT, VAT1, VMAT1 solute carrier family 18 (vesicular monoamine transporter), member 1 C00001429
6571 SLC18A2, SVAT, SVMT, VAT2, VMAT2 solute carrier family 18 (vesicular monoamine transporter), member 2 C00001429
85413 SLC22A16, CT2, FLIPT2, OAT6, OCT6, OKB1, dJ261K5.1 solute carrier family 22 (organic cation/carnitine transporter), member 16 C00001429
6530 SLC6A2, NAT1, NET, NET1, SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 2 C00001429
6531 SLC6A3, DAT, DAT1, PKDYS solute carrier family 6 (neurotransmitter transporter), member 3 C00001429
6532 SLC6A4, 5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT solute carrier family 6 (neurotransmitter transporter), member 4 C00001429
6814 STXBP3, MUNC18-3, MUNC18C, PSP, UNC-18C syntaxin binding protein 3 C00001429
134864 TAAR1, RP11-295F4.9, TA1, TAR1, TRAR1 trace amine associated receptor 1 C00001429
7166 TPH1, TPRH, TRPH, TPH tryptophan hydroxylase 1 (EC:1.14.16.4) C00001429
8989 TRPA1, ANKTM1, FEPS transient receptor potential cation channel, subfamily A, member 1 C00001429
54578 UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17) C00001429
7498 XDH, XO, XOR xanthine dehydrogenase (EC:1.17.1.4 1.17.3.2) C00001429
8647 ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP ATP-binding cassette, sub-family B (MDR/TAP), member 11 C00007247
1374 CPT1A, CPT1, CPT1-L, L-CPT1 carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21) C00007247
1591 CYP24A1, CP24, CYP24, HCAI, P450-CC24 cytochrome P450, family 24, subfamily A, polypeptide 1 (EC:1.14.13.126) C00007247
1557 CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19 cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80) C00007247
3992 FADS1, D5D, FADS6, FADSD5, LLCDL1, TU12 fatty acid desaturase 1 (EC:1.14.19.-) C00007247
3827 KNG1, BDK, BK, KNG kininogen 1 C00007247
9971 NR1H4, BAR, FXR, HRR-1, HRR1, RIP14 nuclear receptor subfamily 1, group H, member 4 C00007247
5465 PPARA, NR1C1, PPAR, PPARalpha, hPPAR peroxisome proliferator-activated receptor alpha C00007247
100136658 C00007247
5467 PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB peroxisome proliferator-activated receptor delta C00007247
5468 PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma peroxisome proliferator-activated receptor gamma C00007247
6256 RXRA, NR2B1 retinoid X receptor, alpha C00007247
7421 VDR, NR1I1 vitamin D (1,25- dihydroxyvitamin D3) receptor C00007247

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (189)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#612376 Acute promyelocytic leukemia; apl P10276
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#103780 Alcohol dependence P08172
P14416
P31645
P47869
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#613780 Aortic aneurysm, familial thoracic 7; aat7 Q15746
#609135 Aplastic anemia O14746
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
#600807 Asthma, susceptibility to Q13093
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#614490 Blood group, junior system; jr Q9UNQ0
#210900 Bloom syndrome; blm P54132
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
%606641 Body mass index; bmi P37231
#612560 Bone mineral density quantitative trait locus 12; bmnd12 O75795
#114480 Breast cancer P42336
#300615 Brunner syndrome P21397
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#609338 Carotid intimal medial thickness 1 P37231
#607271 Caspase 8 deficiency Q14790
#604121 Cerebellar ataxia, deafness, and narcolepsy, autosomal dominant; adcadn P26358
#118300 Charcot-marie-tooth disease and deafness Q01453
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#606595 Charcot-marie-tooth disease, axonal, type 2f; cmt2f P04792
#118220 Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a Q01453
#613641 Charcot-marie-tooth disease, recessive intermediate b; cmtrib Q15046
#605479 Cholestasis, benign recurrent intrahepatic, 2; bric2 O95342
#601847 Cholestasis, progressive familial intrahepatic, 2; pfic2 O95342
#114500 Colorectal cancer; crc P18054
P42336
Q14191
#612918 Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi P42336
#615108 Cowden syndrome 5; cws5 P42336
#218800 Crigler-najjar syndrome, type i P22309
P22310
#606785 Crigler-najjar syndrome, type ii P22309
P22310
#162800 Cyclic neutropenia P08246
#613916 Deafness, autosomal recessive 89; dfnb89 Q15046
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#610549 Diabetes mellitus, insulin-resistant, with acanthosis nigricans P06213
#125853 Diabetes mellitus, noninsulin-dependent; niddm P06213
#119900 Digital clubbing, isolated congenital P15428
#246200 Donohue syndrome P06213
#607208 Dravet syndrome P18507
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#237500 Dubin-johnson syndrome; djs Q92887
#613989 Dyskeratosis congenita, autosomal dominant, 2; dkca2 O14746
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#607681 Epilepsy, childhood absence, susceptibility to, 2; eca2 P18507
#612269 Epilepsy, childhood absence, susceptibility to, 5; eca5 P28472
#613060 Epilepsy, idiopathic generalized, susceptibility to, 10; eig10 O14764
#611136 Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 P14867
#609820 Erythrocytosis, familial, 3; ecyt3 Q9GZT9
#133239 Esophageal cancer P04637
P18054
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#230200 Galactokinase deficiency P51570
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#609446 Generalized epilepsy and paroxysmal dyskinesia; gepd Q12791
#604233 Generalized epilepsy with febrile seizures plus, type 1; gefsp1 P18507
#611277 Generalized epilepsy with febrile seizures plus, type 3; gefsp3 P18507
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#143500 Gilbert syndrome P22309
P22310
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#137800 Glioma susceptibility 1; glm1 P04626
P37231
#232300 Glycogen storage disease ii P10253
#139393 Guillain-barre syndrome, familial; gbs Q01453
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#614519 Hemorrhage, intracerebral, susceptibility to; ich P12821
#114550 Hepatocellular carcinoma P08581
P42336
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#143860 Hyperchlorhidrosis, isolated O43570
#149400 Hyperekplexia, hereditary 1; hkpx1 P23415
#609968 Hyperinsulinemic hypoglycemia, familial, 5; hhf5 P06213
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#145900 Hypertrophic neuropathy of dejerine-sottas Q01453
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#146300 Hypophosphatasia, adult P05186
#241510 Hypophosphatasia, childhood P05186
#241500 Hypophosphatasia, infantile P05186
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#147050 Ige responsiveness, atopic; iger Q13093
#612244 Inflammatory bowel disease 13; ibd13 P08183
#614328 Inflammatory skin and bowel disease, neonatal; nisbd P78536
#603932 Intervertebral disc disease; idd P14780
#182000 Keratosis, seborrheic P42336
#601626 Leukemia, acute myeloid; aml P36888
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
P04637
Q14790
#300635 Lymphoproliferative syndrome, x-linked, 2; xlp2 P98170
#608516 Major depressive disorder; mdd P08172
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#602501 Megalencephaly-capillary malformation-polymicrogyria syndrome; mcap P42336
#603387 Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome; mpph P42336
#613839 Megaloblastic anemia due to dihydrofolate reductase deficiency P00374
#615134 Melanoma, cutaneous malignant, susceptibility to, 9; cmm9 O14746
#614104 Mental retardation, autosomal dominant 7; mrd7 Q13627
#300705 Mental retardation, x-linked 17; mrx17 Q99714
%300852 Mental retardation, x-linked 88; mrx88 P50052
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#612624 Microvascular complications of diabetes, susceptibility to, 3; mvcd3 P12821
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#126200 Multiple sclerosis, susceptibility to; ms P08575
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#254600 Myeloperoxidase deficiency; mpod P05164
#159900 Myoclonic dystonia P14416
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#608634 Neuronopathy, distal hereditary motor, type iib; hmn2b P04792
#614116 Neuropathy, hereditary sensory, type ie; hsn1e P26358
#162500 Neuropathy, hereditary, with liability to pressure palsies; hnpp Q01453
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#601665 Obesity P32245
P37231
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
P42336
#260500 Papilloma of choroid plexus; cpp P04637
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#614674 Periodic fever, menstrual cycle-dependent P08908
#604229 Peters anomaly Q16678
#172700 Pick disease of brain P10636
#262190 Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities P06213
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#614278 Platelet-activating factor acetylhydrolase deficiency; pafad Q13093
#614742 Pulmonary fibrosis and/or bone marrow failure, telomere-related, 1; pfbmft1 O14746
#178500 Pulmonary fibrosis, idiopathic; ipf O14746
#605074 Renal cell carcinoma, papillary, 1; rccp1 P08581
#267430 Renal tubular dysgenesis; rtd P12821
#607276 Resting heart rate, variation in P08588
#275210 Restrictive dermopathy, lethal P02545
#615147 Retinal dystrophy, iris coloboma, and comedogenic acne syndrome; rdccas P02753
#600852 Retinitis pigmentosa 17; rp17 P22748
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
%612223 Stature quantitative trait locus 11; stqtl11 Q00534
#601367 Stroke, ischemic P12821
P16109
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#187950 Thrombocythemia 1; thcyt1 P40225
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#190300 Tremor, hereditary essential, 1; etm1 P35462
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#277700 Werner syndrome; wrn Q14191
#610379 West nile virus, susceptibility to P51681
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253
#112100 Yt blood group antigen P22303

KEGG DISEASE (139)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00764 Cri du chat syndrome O14746 (related)
H01132 Aplastic anemia (AA) O14746 (related)
H01299 Idiopathic pulmonary fibrosis O14746 (related)
H00022 Bladder cancer O14746 (marker)
P00533 (related)
P04626 (related)
P04637 (related)
H00024 Prostate cancer O14746 (marker)
P10275 (related)
H00783 Febrile seizures O14764 (related)
P18507 (related)
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
P04637 (marker)
P08581 (related)
Q16790 (marker)
H00624 Familial cholestasis O95342 (related)
H01197 Dihydrofolate reductase (DHFR) deficiency P00374 (related)
H00016 Oral cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P00533 (related)
P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
P04637 (related)
P08581 (related)
P10415 (related)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
P04637 (related)
P08253 (related)
P10415 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
P10415 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
Q01453 (related)
Q15046 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
P37231 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
P04637 (related)
Q92731 (marker)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
P11511 (related)
H00019 Pancreatic cancer P04626 (related)
P04637 (related)
P04637 (marker)
H00027 Ovarian cancer P04626 (related)
P04637 (related)
P42336 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
P04637 (related)
H00046 Cholangiocarcinoma P04626 (related)
P04637 (related)
P08581 (related)
P35354 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
Q01196 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
P10415 (related)
P28907 (marker)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
P10415 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P08253 (related)
P14780 (related)
P35354 (related)
H00029 Vulvar cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
P27487 (marker)
P37231 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
P14679 (marker)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
P10415 (related)
H00044 Cancer of the anal canal P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00856 Distal hereditary motor neuropathies (dHMN) P04792 (related)
H00101 Other phagocyte defects P05164 (related)
H00003 Acute myeloid leukemia (AML) P05164 (marker)
P10276 (related)
P10276 (marker)
P36888 (related)
Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00213 Hypophosphatasia P05186 (related)
H00719 Leprechaunism P06213 (related)
H00942 Rabson-Mendenhall syndrome P06213 (related)
H01228 Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN) P06213 (related)
H01267 Familial hyperinsulinemic hypoglycemia (HHF) P06213 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00079 Asthma P07550 (related)
H00100 Neutropenic disorders P08246 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00516 Isolated orofacial clefts P10276 (related)
H00054 Nasopharyngeal cancer P10415 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00023 Testicular cancer P10696 (marker)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00794 Aromatase excess syndrome P11511 (related)
H01205 Coumarin resistance P11712 (related)
H00083 Allograft rejection P12821 (related)
H00575 Renal tubular dysgenesis P12821 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00808 Idiopathic generalized epilepsies (IGEs) P14867 (related)
P18507 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00548 Brunner syndrome P21397 (related)
H00208 Hyperbilirubinemia P22309 (related)
Q92887 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H00769 Hyperekplexia P23415 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00409 Type II diabetes mellitus P37231 (related)
P49286 (related)
H00227 Congenital amegakaryocytic thrombocytopenia (CAMT) P40225 (marker)
H00192 Xanthinuria P47989 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
Q99714 (related)
H00070 Galactosemia P51570 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
Q14191 (related)
H00107 Other well-defined immunodeficiency syndromes P98170 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00978 Thrombocytopenia (THC) Q01196 (related)
H01296 Hereditary neuropathy with liability to pressure palsies (HNPP) Q01453 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H01258 Generalized epilepsy and paroxysmal dyskinesia (GEPD) Q12791 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00108 Autoimmune lymphoproliferative syndromes (ALPS) Q14790 (related)
H00801 Familial thoracic aortic aneurysm and dissection (TAAD) Q15746 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00236 Congenital polycythemia Q9GZT9 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

150 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D009203 Myocardial Infarction C00001071
C00001179
C00002647
D009422 Nervous System Diseases C00001179
C00001429
C00007247
D012640 Seizures C00001179
C00001429
D002318 Cardiovascular Diseases C00004565
C00001179
D006943 Hyperglycemia C00004565
C00002647
D020521 Stroke C00001179
C00001429
D013276 Stomach Ulcer C00001179
C00001429
D013226 Status Epilepticus C00001179
C00001429
D010146 Pain C00005374
C00001429
D009202 Cardiomyopathies C00004565
C00001179
D001943 Breast Neoplasms C00004565
C00001179
D007249 Inflammation C00001429
C00007247
D009336 Necrosis C00001179
C00001429
D009135 Muscular Diseases C00001179
C00001429
D007022 Hypotension C00001179
C00001429
D006973 Hypertension C00001179
C00001429
D064420 Drug-Related Side Effects and Adverse Reactions C00001179
C00007247
D002375 Catalepsy C00001179
C00001429
D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive C00002647
D001424 Bacterial Infections C00001179
D001766 Blindness C00001179
D001847 Bone Diseases C00001179
D001927 Brain Diseases C00001179
D002545 Brain Ischemia C00001179
D002277 Carcinoma C00001179
D006528 Carcinoma, Hepatocellular C00001179
D018376 Cardiovascular Abnormalities C00001179
D000756 Anemia, Sideroblastic C00001179
D002386 Cataract C00001179
D002471 Cell Transformation, Neoplastic C00001179
D002607 Charcot-Marie-Tooth Disease C00001179
D002869 Chromosome Aberrations C00001179
D003139 Common Cold C00001179
D020918 Complex Regional Pain Syndromes C00001179
D003327 Coronary Disease C00001179
D003681 Dehydration C00001179
D003924 Diabetes Mellitus, Type 2 C00001179
D003928 Diabetic Nephropathies C00001179
D003930 Diabetic Retinopathy C00001179
D056486 Drug-Induced Liver Injury C00001179
D062787 Drug Overdose C00001179
D000749 Anemia, Megaloblastic C00001179
C538011 Eales disease C00001179
D004890 Erythema C00001179
D005221 Fatigue C00001179
D006029 Glycosuria C00001179
D006130 Growth Disorders C00001179
D006212 Hallucinations C00001179
D006330 Heart Defects, Congenital C00001179
D006548 Hernia, Diaphragmatic C00001179
D015658 HIV Infections C00001179
D006959 Hyperoxaluria C00001179
D006965 Hyperplasia C00001179
D018798 Anemia, Iron-Deficiency C00001179
D006977 Hypertension, Renal C00001179
D000740 Anemia C00001179
D007037 Hypothyroidism C00001179
146850 IMMUNE SUPPRESSION C00001179
D007674 Kidney Diseases C00001179
D007683 Kidney Tubular Necrosis, Acute C00001179
D007859 Learning Disorders C00001179
D007945 Leukemia, Lymphoid C00001179
D008103 Liver Cirrhosis C00001179
D008114 Liver Neoplasms, Experimental C00001179
D008171 Lung Diseases C00001179
D008175 Lung Neoplasms C00001179
D020149 Manganese Poisoning C00001179
D008630 Mercury Poisoning C00001179
D048629 Micronuclei, Chromosome-Defective C00001179
D009120 Muscle Cramp C00001179
D000647 Amnesia C00001179
D009325 Nausea C00001179
D055371 Acute Lung Injury C00001179
D009369 Neoplasms C00001179
D009374 Neoplasms, Experimental C00001179
D009395 Nephritis, Interstitial C00001179
D053040 Nephrolithiasis C00001179
D009410 Nerve Degeneration C00001179
D058186 Acute Kidney Injury C00001179
D009765 Obesity C00001179
D009845 Oligospermia C00001179
D010149 Pain, Postoperative C00001179
D010212 Papilloma C00001179
D016491 Peripheral Vascular Diseases C00001179
D011041 Poisoning C00001179
D011230 Precancerous Conditions C00001179
D011471 Prostatic Neoplasms C00001179
D011507 Proteinuria C00001179
D011561 Pseudoxanthoma Elasticum C00001179
D011605 Psychoses, Substance-Induced C00001179
D011654 Pulmonary Edema C00001179
D011657 Pulmonary Eosinophilia C00001179
D011658 Pulmonary Fibrosis C00001179
D051437 Renal Insufficiency C00001179
D012174 Retinitis Pigmentosa C00001179
D012614 Scurvy C00001179
D005909 Glioblastoma C00001071
D012871 Skin Diseases C00001179
D011297 Prenatal Exposure Delayed Effects C00004565
D013274 Stomach Neoplasms C00001179
D010024 Osteoporosis C00004565
D007938 Leukemia C00004565
D013375 Substance Withdrawal Syndrome C00001179
D013921 Thrombocytopenia C00001179
D001749 Urinary Bladder Neoplasms C00001179
D003921 Diabetes Mellitus, Experimental C00002647
D050171 Dyslipidemias C00002647
D005234 Fatty Liver C00002647
D018149 Glucose Intolerance C00002647
D006937 Hypercholesterolemia C00002647
D006949 Hyperlipidemias C00002647
D015228 Hypertriglyceridemia C00002647
D001206 Ascorbic Acid Deficiency C00001179
D008546 Melanoma, Experimental C00002647
D009069 Movement Disorders C00002647
D009361 Neoplasm Invasiveness C00002647
D009362 Neoplasm Metastasis C00002647
D012516 Osteosarcoma C00002647
D010182 Pancreatic Diseases C00002647
D000544 Alzheimer Disease C00001429
D000648 Amnesia, Retrograde C00001429
D001008 Anxiety Disorders C00001429
D001022 Aortic Valve Insufficiency C00001429
D001049 Apnea C00001429
D001281 Atrial Fibrillation C00001429
D001321 Autistic Disorder C00001429
D001919 Bradycardia C00001429
D002389 Catatonia C00001429
D002659 Child Development Disorders, Pervasive C00001429
D021081 Chronobiology Disorders C00001429
D015140 Dementia, Vascular C00001429
D003967 Diarrhea C00001429
D004195 Disease Models, Animal C00001429
D004487 Edema C00001429
D005355 Fibrosis C00001429
D005483 Flushing C00001429
D006349 Heart Valve Diseases C00001429
D006930 Hyperalgesia C00001429
D006976 Hypertension, Pulmonary C00001429
D017379 Hypertrophy, Left Ventricular C00001429
D050197 Atherosclerosis C00004565
D043183 Irritable Bowel Syndrome C00001429
D008944 Mitral Valve Insufficiency C00001429
D011537 Pruritus C00001429
D020230 Serotonin Syndrome C00001429
D013610 Tachycardia C00001429
D059246 Tachypnea C00001429
D014202 Tremor C00001429
D001930 Brain Injuries C00007247
D003866 Depressive Disorder C00007247