Plant Species


Cumulative plant class count

class name count
asterids 5
rosids 1

Cumulative family count

class name count
Solanaceae 5
Schilbeidae 1
Elaeagnaceae 1

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (7)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00022178 External link 512 Anhydrovitamin A1
C031469
0 / 1
C00022184 External link 512 Apo-15-zeaxanthinal
/ (3R)-3-Hydroxyretinal
CHEMBL256122
2 / 0 / 0
C00022187 External link 512 Apo-14'-zeaxanthinal
C00022188 External link 512 Apo-15-zeaxanthinal
CHEMBL256122
2 / 0 / 0
C00022189 External link 512 Apo-13-zeaxanthinone
C00022190 External link 512 Apo-11-zeaxanthinal
C00031437 External link 512 Vitamin A
CHEMBL986
CHEMBL1454290
CHEMBL1595345
28 / 26 / 26

Human Protein / Gene in interactions

30 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O60218 Aldo-keto reductase family 1 member B10 Enzyme C00022184 C00022188 0 / 0
P15121 Aldose reductase Enzyme C00022184 C00022188 0 / 0
P10145 Interleukin-8 Secreted protein C00031437 0 / 0
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00031437 2 / 2
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00031437 0 / 0
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00031437 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00031437 3 / 2
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00031437 0 / 0
P10276 Retinoic acid receptor alpha NR1B1 C00031437 1 / 2
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00031437 1 / 1
P11473 Vitamin D3 receptor NR1I1 C00031437 2 / 3
P00352 Retinal dehydrogenase 1 Enzyme C00031437 0 / 0
P02753 Retinol-binding protein 4 Secreted protein C00031437 1 / 0
O75496 Geminin Unclassified protein C00031437 0 / 0
P22310 UDP-glucuronosyltransferase 1-4 Enzyme C00031437 3 / 0
P27338 Amine oxidase [flavin-containing] B Oxidoreductase C00031437 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00031437 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00031437 0 / 1
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00031437 5 / 3
P28482 Mitogen-activated protein kinase 1 Erk C00031437 0 / 0
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00031437 0 / 0
P03372 Estrogen receptor NR3A1 C00031437 1 / 1
P16050 Arachidonate 15-lipoxygenase Enzyme C00031437 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00031437 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00031437 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00031437 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00031437 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00031437 0 / 0
O00255 Menin Unclassified protein C00031437 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00031437 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (26)

OMIM preferred title UniProt
#612376 Acute promyelocytic leukemia; apl P10276
%606641 Body mass index; bmi P37231
#300615 Brunner syndrome P21397
#609338 Carotid intimal medial thickness 1 P37231
#218800 Crigler-najjar syndrome, type i P22310
#606785 Crigler-najjar syndrome, type ii P22310
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#143500 Gilbert syndrome P22310
#137800 Glioma susceptibility 1; glm1 P37231
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613688 Long qt syndrome 2; lqt2 Q12809
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#601665 Obesity P37231
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#615147 Retinal dystrophy, iris coloboma, and comedogenic acne syndrome; rdccas P02753
#609620 Short qt syndrome 1; sqt1 Q12809
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (26)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00026 Endometrial Cancer P03372 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00036 Osteosarcoma P08684 (marker)
H00003 Acute myeloid leukemia (AML) P10276 (related)
P10276 (marker)
H00516 Isolated orofacial clefts P10276 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00548 Brunner syndrome P21397 (related)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D009336 Necrosis C00022178