PCIDB

KNApSAcK Metabolite C00002647

Metabolite

KNApSAcK Entry

id C00002647
Name Gallic acid
CAS RN 149-91-7
Standard InChI InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12)
Standard InChI (Main Layer) InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12)

Cluster

Phytochemical cluster No. 81
KCF-S cluster No. 817

Link

ChEMBL

By standard InChI CHEMBL288114
By standard InChI Main Layer CHEMBL288114

KEGG

By LinkDB C01424

CTD

By CAS RN D005707

Species

Summary

Plant class

class name count
rosids 49
eudicotyledons 8
asterids 5
Spermatophyta 2
Liliopsida 2
Magnoliophyta 1

Family (Top 10)

family name count
Fabaceae 14
Anacardiaceae 6
Myrtaceae 5
Melastomataceae 3
Euphorbiaceae 3
Phyllanthaceae 3
Geraniaceae 2
Polygonaceae 2
Clusiaceae 2
Sarcolaenaceae 2

List (70)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Acacia cyanophylla 420411 Fabaceae rosids Viridiplantae
Acacia farnesiana 72368 Fabaceae rosids Viridiplantae
Acacia horrida 3808 Fabaceae rosids Viridiplantae
Acacia longifolia 139010 Fabaceae rosids Viridiplantae
Acacia mellifera 381101 Fabaceae rosids Viridiplantae
Acacia nilotica 138033 Fabaceae rosids Viridiplantae
Acacia polyacantha subsp.camphylacantha 3808 Fabaceae rosids Viridiplantae
Acacia saligna 420411 Fabaceae rosids Viridiplantae
Acacia seyal 138044 Fabaceae rosids Viridiplantae
Acacia sieberiana 546664 Fabaceae rosids Viridiplantae
Acacia tortilis 138046 Fabaceae rosids Viridiplantae
Acer rubrum L. 45314 Aceraceae rosids Viridiplantae
Allanblackia floribunda 469914 Clusiaceae rosids Viridiplantae
Ardisia colorata 1009002 Primulaceae asterids Viridiplantae
Balanophora japonica 1128102 Balanophoraceae eudicotyledons Viridiplantae
Bridelia micrantha 577023 Phyllanthaceae rosids Viridiplantae
Caesalpinia pulcherrima 53846 Fabaceae rosids Viridiplantae
Caesalpinia sappan 483143 Fabaceae rosids Viridiplantae
Combretum quadrangulare 99434 Combretaceae rosids Viridiplantae
Cotinus coggygria 269719 Anacardiaceae rosids Viridiplantae
Cowania mexicana 3745 Rosaceae rosids Viridiplantae
Croton tonkinensis GAGNEP 100370 Euphorbiaceae rosids Viridiplantae
Cunonia macrophylla 140420 Cunoniaceae rosids Viridiplantae
Dillenia indica 4378 Dilleniaceae eudicotyledons Viridiplantae
Diospyros cinnabarina 13492 Ebenaceae asterids Viridiplantae
Equsetum arvense
Eskemukerjea megacarpum HARA 3615 Polygonaceae eudicotyledons Viridiplantae
Eugenia edulis 119950 Myrtaceae rosids Viridiplantae
Eugenia jambolana 260142 Myrtaceae rosids Viridiplantae
Garcinia densivenia 58227 Clusiaceae rosids Viridiplantae
Geranium macrorrhizum L. 28963 Geraniaceae rosids Viridiplantae
Geranium thunbergii 345239 Geraniaceae rosids Viridiplantae
Haematoxylon campechianum
Hippophae rhamnoides 193516 Elaeagnaceae rosids Viridiplantae
Juglans mandshurica 91218 Juglandaceae rosids Viridiplantae
Leptolaena diospyroidea 217266 Sarcolaenaceae rosids Viridiplantae
Leptolaena pauciflora 217266 Sarcolaenaceae rosids Viridiplantae
Macaranga barteri 396451 Euphorbiaceae rosids Viridiplantae
Mallotus furetianus 3977 Euphorbiaceae rosids Viridiplantae
Manilkara zapota cv.Tikal 3740 Sapotaceae asterids Viridiplantae
Melastoma intermedium 658897 Melastomataceae rosids Viridiplantae
Miconia cabucu 477031 Melastomataceae rosids Viridiplantae
Miconia myriantha 263288 Melastomataceae rosids Viridiplantae
Nymphaea caerulea 49506 Nymphaeaceae Magnoliophyta Viridiplantae
Paratecoma peroba 24079 Bignoniaceae asterids Viridiplantae
Peltophorum africanum 321567 Fabaceae rosids Viridiplantae
Phyllanthus emblica 296036 Phyllanthaceae rosids Viridiplantae
Phyllanthus niruri 296034 Phyllanthaceae rosids Viridiplantae
Pimenta dioica 375272 Myrtaceae rosids Viridiplantae
Pistacia weinmannifolia J.Pisson ex.Franch 55512 Anacardiaceae rosids Viridiplantae
Polygonum cuspidatum 83819 Polygonaceae eudicotyledons Viridiplantae
Posidonia oceanica 55489 Posidoniaceae Liliopsida Viridiplantae
Pseudolarix kaempferi Gord. 3354 Pinaceae Spermatophyta Viridiplantae
Psidium guajava 120290 Myrtaceae rosids Viridiplantae
Psittacanthus cucullaris 50160 Loranthaceae eudicotyledons Viridiplantae
Punica granatum 22663 Lythraceae rosids Viridiplantae
Rhaponticum carthamoides 362630 Asteraceae asterids Viridiplantae
Rhodiola sachalinensis 265354 Crassulaceae eudicotyledons Viridiplantae
Rhus semialata 4012 Anacardiaceae rosids Viridiplantae
Rhus typhina 255348 Anacardiaceae rosids Viridiplantae
Rhus wallichi 4012 Anacardiaceae rosids Viridiplantae
Sarcolaeana multiflora
Sedum takesimense Nakai 904691 Crassulaceae eudicotyledons Viridiplantae
Semecarpus vitiensis 173682 Anacardiaceae rosids Viridiplantae
Syzygium cordatum 334476 Myrtaceae rosids Viridiplantae
Tamarix nilotica 189799 Tamaricaceae eudicotyledons Viridiplantae
Taxus baccata 25629 Taxaceae Spermatophyta Viridiplantae
Terminalia superba 39992 Combretaceae rosids Viridiplantae
Typha domingensis P. 4732 Typhaceae Liliopsida Viridiplantae
Vitis vinifera 29760 Vitaceae rosids Viridiplantae

Human Protein / Gene in interaction

42 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P04637 Cellular tumor antigen p53 Transcription Factor CHEMBL288114 CHEMBL1613992 (1) CHEMBL1613995 (1)
7 / 44
Q16637 Survival motor neuron protein Unclassified protein CHEMBL288114 CHEMBL1613842 (1)
4 / 2
P35354 Prostaglandin G/H synthase 2 Oxidoreductase CHEMBL288114 CHEMBL1014033 (1)
0 / 3
Q13093 Platelet-activating factor acetylhydrolase Enzyme CHEMBL288114 CHEMBL1032505 (1)
3 / 0
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase CHEMBL288114 CHEMBL1074270 (1)
0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase CHEMBL288114 CHEMBL1074269 (1)
0 / 0
P43166 Carbonic anhydrase 7 Lyase CHEMBL288114 CHEMBL1074272 (1)
0 / 0
P04406 Glyceraldehyde-3-phosphate dehydrogenase Enzyme CHEMBL288114 CHEMBL1613955 (1)
0 / 0
P02545 Prelamin-A/C Unclassified protein CHEMBL288114 CHEMBL1614544 (1)
11 / 10
P00918 Carbonic anhydrase 2 Lyase CHEMBL288114 CHEMBL1074266 (1)
1 / 2
P78536 Disintegrin and metalloproteinase domain-containing protein 17 M12B CHEMBL288114 CHEMBL2339513 (1) CHEMBL2339514 (1)
CHEMBL2339515 (1)
1 / 0
P11473 Vitamin D3 receptor NR1I1 CHEMBL288114 CHEMBL1794311 (1)
2 / 3
P23280 Carbonic anhydrase 6 Lyase CHEMBL288114 CHEMBL1074271 (1)
0 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase CHEMBL288114 CHEMBL1074276 (1)
0 / 0
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL288114 CHEMBL1614458 (2)
0 / 0
P16581 E-selectin Adhesion CHEMBL288114 CHEMBL917093 (1)
0 / 0
O43570 Carbonic anhydrase 12 Lyase CHEMBL288114 CHEMBL1074274 (1)
1 / 2
Q92830 Histone acetyltransferase KAT2A Enzyme CHEMBL288114 CHEMBL1738606 (1)
0 / 0
P15121 Aldose reductase Enzyme CHEMBL288114 CHEMBL984565 (1)
0 / 0
P10145 Interleukin-8 Secreted protein CHEMBL288114 CHEMBL2114835 (1)
0 / 0
P00915 Carbonic anhydrase 1 Lyase CHEMBL288114 CHEMBL1074265 (1)
0 / 0
P04150 Glucocorticoid receptor NR3C1 CHEMBL288114 CHEMBL1794382 (1)
0 / 1
P08581 Hepatocyte growth factor receptor TK tyrosine-protein kinase MET subfamily CHEMBL288114 CHEMBL1056839 (1)
2 / 3
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL288114 CHEMBL1614521 (1) CHEMBL1613808 (1)
0 / 0
Q16790 Carbonic anhydrase 9 Lyase CHEMBL288114 CHEMBL1074273 (1)
0 / 1
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme CHEMBL288114 CHEMBL1613910 (1) CHEMBL1614227 (1)
3 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme CHEMBL288114 CHEMBL1614038 (1)
2 / 2
P03372 Estrogen receptor NR3A1 CHEMBL288114 CHEMBL1794364 (1) CHEMBL1941568 (1)
CHEMBL1941569 (1)
1 / 1
P12821 Angiotensin-converting enzyme M2 CHEMBL288114 CHEMBL1015636 (1)
4 / 2
P14151 L-selectin Adhesion CHEMBL288114 CHEMBL917097 (1)
0 / 0
P16109 P-selectin Adhesion CHEMBL288114 CHEMBL917095 (1)
1 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme CHEMBL288114 CHEMBL1614211 (2)
0 / 0
P22309 UDP-glucuronosyltransferase 1-1 Enzyme CHEMBL288114 CHEMBL1908080 (1)
5 / 1
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL288114 CHEMBL1614250 (1) CHEMBL1614421 (1)
CHEMBL1614502 (1)
4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein CHEMBL288114 CHEMBL2114890 (1)
0 / 0
P07451 Carbonic anhydrase 3 Lyase CHEMBL288114 CHEMBL1074267 (1)
0 / 0
P22748 Carbonic anhydrase 4 Lyase CHEMBL288114 CHEMBL1074268 (1)
1 / 1
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL288114 CHEMBL1794536 (1)
0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL288114 CHEMBL1613914 (1)
0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL288114 CHEMBL1738442 (1)
0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme CHEMBL288114 CHEMBL1614364 (2) CHEMBL1738394 (1)
1 / 1
O94925 Glutaminase kidney isoform, mitochondrial Enzyme CHEMBL288114 CHEMBL2114738 (1)
0 / 0

CTD interaction (103)

compound gene gene name gene description interaction interaction type form reference
pmid
D005707 5243 ABCB1
ABC20
CD243
CLCS
GP170
MDR1
P-GP
PGY1
ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) Gallic Acid results in decreased expression of ABCB1 protein decreases expression
protein 20513373
D005707 25 ABL1
ABL
JTK7
bcr/abl
c-ABL
p150
v-abl
c-abl oncogene 1, non-receptor tyrosine kinase (EC:2.7.10.2) Gallic Acid promotes the reaction [imatinib results in decreased phosphorylation of [BCR protein mutant form binds to ABL1 protein mutant form]] affects binding
/ decreases phosphorylation
/ increases reaction
protein 22245431
D005707 25 ABL1
ABL
JTK7
bcr/abl
c-ABL
p150
v-abl
c-abl oncogene 1, non-receptor tyrosine kinase (EC:2.7.10.2) Gallic Acid results in decreased phosphorylation of [BCR protein mutant form binds to ABL1 protein mutant form] affects binding
/ decreases phosphorylation
protein 22245431
D005707 25 ABL1
ABL
JTK7
bcr/abl
c-ABL
p150
v-abl
c-abl oncogene 1, non-receptor tyrosine kinase (EC:2.7.10.2) imatinib promotes the reaction [Gallic Acid results in decreased phosphorylation of [BCR protein mutant form binds to ABL1 protein mutant form]] affects binding
/ decreases phosphorylation
/ increases reaction
protein 22245431
D005707 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) Gallic Acid results in decreased activity of AKT1 protein decreases activity
protein 22387266
D005707 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) Gallic Acid results in decreased phosphorylation of AKT1 protein decreases phosphorylation
protein 23153558
D005707 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) RHOB mutant form inhibits the reaction [Gallic Acid results in decreased phosphorylation of AKT1 protein] decreases phosphorylation
/ decreases reaction
protein 23153558
D005707 338 APOB
FLDB
LDLCQ4
apolipoprotein B Gallic Acid results in decreased secretion of APOB protein decreases secretion
protein 12612140
D005707 472 ATM
AT1
ATA
ATC
ATD
ATDC
ATE
TEL1
TELO1
ataxia telangiectasia mutated (EC:2.7.11.1) Gallic Acid results in decreased expression of ATM mRNA decreases expression
mRNA 21887735
D005707 545 ATR
FCTCS
FRP1
MEC1
SCKL
SCKL1
ataxia telangiectasia and Rad3 related (EC:2.7.11.1) Gallic Acid results in decreased expression of ATR mRNA decreases expression
mRNA 21887735
D005707 581 BAX
BCL2L4
BCL2-associated X protein Gallic Acid results in increased expression of BAX protein increases expression
protein 22245431
D005707 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Gallic Acid inhibits the reaction [TNF protein results in increased expression of BCL2 mRNA] decreases reaction
/ increases expression
mRNA 21420233
D005707 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 Gallic Acid results in decreased expression of BCL2 protein decreases expression
protein 22245431
D005707 613 BCR
ALL
BCR1
CML
D22S11
D22S662
PHL
breakpoint cluster region (EC:2.7.11.1) Gallic Acid promotes the reaction [imatinib results in decreased phosphorylation of [BCR protein mutant form binds to ABL1 protein mutant form]] affects binding
/ decreases phosphorylation
/ increases reaction
protein 22245431
D005707 613 BCR
ALL
BCR1
CML
D22S11
D22S662
PHL
breakpoint cluster region (EC:2.7.11.1) Gallic Acid results in decreased phosphorylation of [BCR protein mutant form binds to ABL1 protein mutant form] affects binding
/ decreases phosphorylation
protein 22245431
D005707 613 BCR
ALL
BCR1
CML
D22S11
D22S662
PHL
breakpoint cluster region (EC:2.7.11.1) imatinib promotes the reaction [Gallic Acid results in decreased phosphorylation of [BCR protein mutant form binds to ABL1 protein mutant form]] affects binding
/ decreases phosphorylation
/ increases reaction
protein 22245431
D005707 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) Gallic Acid results in increased expression of CASP3 protein increases expression
protein 22245431
D005707 841 CASP8
ALPS2B
CAP4
Casp-8
FLICE
MACH
MCH5
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) Gallic Acid results in increased expression of CASP8 protein increases expression
protein 22245431
D005707 898 CCNE1
CCNE
cyclin E1 Gallic Acid results in decreased expression of CCNE1 protein decreases expression
protein 22245431
D005707 998 CDC42
CDC42Hs
G25K
cell division cycle 42 Gallic Acid results in decreased expression of CDC42 protein decreases expression
protein 23153558
D005707 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) Gallic Acid results in increased expression of CDKN1A protein increases expression
protein 22245431
D005707 1027 CDKN1B
CDKN4
KIP1
MEN1B
MEN4
P27KIP1
cyclin-dependent kinase inhibitor 1B (p27, Kip1) Gallic Acid results in increased expression of CDKN1B protein increases expression
protein 22245431
D005707 1147 CHUK
IKBKA
IKK-alpha
IKK1
IKKA
NFKBIKA
TCF16
conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) Gallic Acid inhibits the reaction [TNF protein results in increased phosphorylation of CHUK protein] decreases reaction
/ increases phosphorylation
protein 21420233
D005707 1147 CHUK
IKBKA
IKK-alpha
IKK1
IKKA
NFKBIKA
TCF16
conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) Gallic Acid results in decreased activity of CHUK protein decreases activity
protein 22387266
D005707 7852 CXCR4
CD184
D2S201E
FB22
HM89
HSY3RR
LAP3
LCR1
LESTR
NPY3R
NPYR
NPYRL
NPYY3R
WHIM
chemokine (C-X-C motif) receptor 4 Gallic Acid inhibits the reaction [TNF protein results in increased expression of CXCR4 mRNA] decreases reaction
/ increases expression
mRNA 21420233
D005707 54205 CYCS
CYC
HCS
THC4
cytochrome c, somatic Gallic Acid affects the localization of CYCS protein affects localization
protein 22245431
D005707 54205 CYCS
CYC
HCS
THC4
cytochrome c, somatic Gallic Acid results in increased expression of CYCS protein increases expression
protein 22245431
D005707 356 FASLG
ALPS1B
APT1LG1
APTL
CD178
CD95-L
CD95L
FASL
TNFSF6
Fas ligand (TNF superfamily, member 6) Gallic Acid results in increased expression of FASLG protein increases expression
protein 22245431
D005707 2551 GABPA
E4TF1-60
E4TF1A
NFT2
NRF2
NRF2A
RCH04A07
GA binding protein transcription factor, alpha subunit 60kDa anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Gallic Acid results in increased expression of GABPA protein] decreases reaction
/ increases expression
protein 16308312
D005707 2551 GABPA
E4TF1-60
E4TF1A
NFT2
NRF2
NRF2A
RCH04A07
GA binding protein transcription factor, alpha subunit 60kDa Gallic Acid affects the localization of and results in increased activity of GABPA protein affects localization
/ increases activity
protein 16308312
D005707 2551 GABPA
E4TF1-60
E4TF1A
NFT2
NRF2
NRF2A
RCH04A07
GA binding protein transcription factor, alpha subunit 60kDa SB 203580 inhibits the reaction [Gallic Acid results in increased expression of GABPA protein] decreases reaction
/ increases expression
protein 16308312
D005707 2885 GRB2
ASH
EGFRBP-GRB2
Grb3-3
MST084
MSTP084
NCKAP2
growth factor receptor-bound protein 2 Gallic Acid results in decreased expression of GRB2 protein decreases expression
protein 22387266
D005707 3551 IKBKB
IKK-beta
IKK2
IKKB
NFKBIKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) Gallic Acid inhibits the reaction [TNF protein results in increased phosphorylation of IKBKB protein] decreases reaction
/ increases phosphorylation
protein 21420233
D005707 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Gallic Acid inhibits the reaction [TNF protein results in increased expression of IL6 mRNA] decreases reaction
/ increases expression
mRNA 21420233
D005707 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) Gallic Acid inhibits the reaction [TNF protein results in increased secretion of IL6 protein] decreases reaction
/ increases secretion
protein 21420233
D005707 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Gallic Acid inhibits the reaction [TNF protein results in increased expression of IL8 mRNA] decreases reaction
/ increases expression
mRNA 21420233
D005707 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 Gallic Acid inhibits the reaction [TNF protein results in increased secretion of IL8 protein] decreases reaction
/ increases secretion
protein 21420233
D005707 3949 LDLR
FH
FHC
LDLCQ2
low density lipoprotein receptor Gallic Acid results in increased expression of LDLR mRNA increases expression
mRNA 12612140
D005707 5604 MAP2K1
CFC3
MAPKK1
MEK1
MKK1
PRKMK1
mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) Gallic Acid inhibits the reaction [TNF protein results in increased phosphorylation of MAP2K1 protein] decreases reaction
/ increases phosphorylation
protein 21420233
D005707 5594 MAPK1
ERK
ERK2
ERT1
MAPK2
P42MAPK
PRKM1
PRKM2
p38
p40
p41
p41mapk
mitogen-activated protein kinase 1 (EC:2.7.11.24) Gallic Acid results in decreased expression of MAPK1 protein modified form decreases expression
protein 22387266
D005707 5595 MAPK3
ERK-1
ERK1
ERT2
HS44KDAP
HUMKER1A
P44ERK1
P44MAPK
PRKM3
p44-ERK1
p44-MAPK
mitogen-activated protein kinase 3 (EC:2.7.11.24) Gallic Acid results in decreased expression of MAPK3 protein modified form decreases expression
protein 22387266
D005707 5599 MAPK8
JNK
JNK-46
JNK1
JNK1A2
JNK21B1/2
PRKM8
SAPK1
SAPK1c
mitogen-activated protein kinase 8 (EC:2.7.11.24) Gallic Acid inhibits the reaction [TNF protein results in increased phosphorylation of MAPK8 protein] decreases reaction
/ increases phosphorylation
protein 21420233
D005707 5601 MAPK9
JNK-55
JNK2
JNK2A
JNK2ALPHA
JNK2B
JNK2BETA
PRKM9
SAPK
SAPK1a
p54a
p54aSAPK
mitogen-activated protein kinase 9 (EC:2.7.11.24) Gallic Acid inhibits the reaction [TNF protein results in increased phosphorylation of MAPK9 protein] decreases reaction
/ increases phosphorylation
protein 21420233
D005707 4255 MGMT
O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63) Gallic Acid results in decreased expression of MGMT mRNA decreases expression
mRNA 21887735
D005707 4313 MMP2
CLG4
CLG4A
MMP-II
MONA
TBE-1
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) Gallic Acid results in decreased activity of MMP2 protein decreases activity
protein 22387266
D005707 4313 MMP2
CLG4
CLG4A
MMP-II
MONA
TBE-1
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) Gallic Acid results in decreased expression of MMP2 mRNA decreases expression
mRNA 22387266
D005707 4313 MMP2
CLG4
CLG4A
MMP-II
MONA
TBE-1
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) Gallic Acid results in decreased expression of MMP2 protein decreases expression
protein 22387266
23153558
D005707 4313 MMP2
CLG4
CLG4A
MMP-II
MONA
TBE-1
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) RHOB mutant form inhibits the reaction [Gallic Acid results in decreased expression of MMP2 protein] decreases expression
/ decreases reaction
protein 23153558
D005707 4316 MMP7
MMP-7
MPSL1
PUMP-1
matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23) Gallic Acid inhibits the reaction [epigallocatechin gallate results in increased expression of MMP7 protein] decreases reaction
/ increases expression
protein 17928719
D005707 4316 MMP7
MMP-7
MPSL1
PUMP-1
matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23) Gallic Acid inhibits the reaction [Tretinoin results in increased expression of MMP7 mRNA] decreases reaction
/ increases expression
mRNA 17928719
D005707 4316 MMP7
MMP-7
MPSL1
PUMP-1
matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23) Gallic Acid results in decreased expression of MMP7 mRNA decreases expression
mRNA 22387266
D005707 4318 MMP9
CLG4B
GELB
MANDP2
MMP-9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) Gallic Acid results in decreased activity of MMP9 protein decreases activity
protein 22387266
D005707 4318 MMP9
CLG4B
GELB
MANDP2
MMP-9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) Gallic Acid results in decreased expression of MMP9 mRNA decreases expression
mRNA 22387266
D005707 4318 MMP9
CLG4B
GELB
MANDP2
MMP-9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) Gallic Acid results in decreased expression of MMP9 protein decreases expression
protein 22387266
D005707 4793 NFKBIB
IKBB
TRIP9
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta Gallic Acid inhibits the reaction [TNF protein results in increased degradation of NFKBIB protein] decreases reaction
/ increases degradation
protein 21420233
D005707 5578 PRKCA
AAG6
PKC-alpha
PKCA
PRKACA
protein kinase C, alpha (EC:2.7.11.13) Gallic Acid results in decreased activity of PRKCA protein decreases activity
protein 22387266
D005707 5591 PRKDC
DNA-PKcs
DNAPK
DNPK1
HYRC
HYRC1
XRCC7
p350
protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1) Gallic Acid results in decreased expression of PRKDC mRNA decreases expression
mRNA 21887735
D005707 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) Gallic Acid inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA] decreases reaction
/ increases expression
mRNA 21420233
D005707 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) Gallic Acid promotes the reaction [imatinib results in decreased expression of PTGS2 protein] decreases expression
/ increases reaction
protein 22245431
D005707 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) Gallic Acid results in decreased expression of PTGS2 protein decreases expression
protein 22245431
D005707 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) imatinib promotes the reaction [Gallic Acid results in decreased expression of PTGS2 protein] decreases expression
/ increases reaction
protein 22245431
D005707 5879 RAC1
Rac-1
TC-25
p21-Rac1
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) Gallic Acid results in decreased expression of RAC1 protein decreases expression
protein 23153558
D005707 19412 Gallic Acid results in decreased expression of RAS protein decreases expression
protein 23153558
D005707 5970 RELA
NFKB3
p65
v-rel avian reticuloendotheliosis viral oncogene homolog A Gallic Acid inhibits the reaction [TNF protein affects the localization of and affects the activity of RELA protein] affects activity
/ affects localization
/ decreases reaction
protein 21420233
D005707 5970 RELA
NFKB3
p65
v-rel avian reticuloendotheliosis viral oncogene homolog A Gallic Acid results in decreased expression of RELA protein decreases expression
protein 22245431
D005707 387 RHOA
ARH12
ARHA
RHO12
RHOH12
ras homolog family member A Gallic Acid results in decreased expression of RHOA protein decreases expression
protein 23153558
D005707 388 RHOB
ARH6
ARHB
MST081
MSTP081
RHOH6
ras homolog family member B Gallic Acid results in increased expression of RHOB mRNA increases expression
mRNA 23153558
D005707 388 RHOB
ARH6
ARHB
MST081
MSTP081
RHOH6
ras homolog family member B Gallic Acid results in increased expression of RHOB protein increases expression
protein 23153558
D005707 388 RHOB
ARH6
ARHB
MST081
MSTP081
RHOH6
ras homolog family member B RHOB mutant form inhibits the reaction [Gallic Acid results in decreased expression of MMP2 protein] decreases expression
/ decreases reaction
mutant form 23153558
D005707 388 RHOB
ARH6
ARHB
MST081
MSTP081
RHOH6
ras homolog family member B RHOB mutant form inhibits the reaction [Gallic Acid results in decreased phosphorylation of AKT1 protein] decreases phosphorylation
/ decreases reaction
mutant form 23153558
D005707 388 RHOB
ARH6
ARHB
MST081
MSTP081
RHOH6
ras homolog family member B RHOB protein results in increased susceptibility to Gallic Acid increases response to substance
protein 23153558
D005707 6195 RPS6KA1
HU-1
MAPKAPK1A
RSK
RSK1
ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1) Gallic Acid inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KA1 protein] decreases reaction
/ increases phosphorylation
protein 21420233
D005707 9252 RPS6KA5
MSK1
MSPK1
RLPK
ribosomal protein S6 kinase, 90kDa, polypeptide 5 (EC:2.7.11.1) Gallic Acid inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KA5 protein] decreases reaction
/ increases phosphorylation
protein 21420233
D005707 6622 SNCA
NACP
PARK1
PARK4
PD1
synuclein, alpha (non A4 component of amyloid precursor) Gallic Acid inhibits the reaction [SNCA protein binds to SNCA protein] affects binding
/ decreases reaction
protein 20150427
D005707 6817 SULT1A1
HAST1/HAST2
P-PST
PST
ST1A1
ST1A3
STP
STP1
TSPST1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Gallic Acid results in increased expression of SULT1A1 protein] decreases reaction
/ increases expression
protein 16308312
D005707 6817 SULT1A1
HAST1/HAST2
P-PST
PST
ST1A1
ST1A3
STP
STP1
TSPST1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) Cycloheximide inhibits the reaction [Gallic Acid results in increased expression of SULT1A1 mRNA] decreases reaction
/ increases expression
mRNA 16308312
D005707 6817 SULT1A1
HAST1/HAST2
P-PST
PST
ST1A1
ST1A3
STP
STP1
TSPST1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) Dactinomycin inhibits the reaction [Gallic Acid results in increased expression of SULT1A1 mRNA] decreases reaction
/ increases expression
mRNA 16308312
D005707 6817 SULT1A1
HAST1/HAST2
P-PST
PST
ST1A1
ST1A3
STP
STP1
TSPST1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) Gallic Acid results in increased activity of SULT1A1 protein increases activity
protein 16308312
D005707 6817 SULT1A1
HAST1/HAST2
P-PST
PST
ST1A1
ST1A3
STP
STP1
TSPST1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) Gallic Acid results in increased expression of SULT1A1 protein increases expression
protein 16308312
D005707 6817 SULT1A1
HAST1/HAST2
P-PST
PST
ST1A1
ST1A3
STP
STP1
TSPST1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) SB 203580 inhibits the reaction [Gallic Acid results in increased expression of SULT1A1 protein] decreases reaction
/ increases expression
protein 16308312
D005707 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Gallic Acid inhibits the reaction [TNF protein affects the localization of and affects the activity of RELA protein] affects activity
/ affects localization
/ decreases reaction
protein 21420233
D005707 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Gallic Acid inhibits the reaction [TNF protein results in increased degradation of NFKBIB protein] decreases reaction
/ increases degradation
protein 21420233
D005707 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Gallic Acid inhibits the reaction [TNF protein results in increased expression of BCL2 mRNA] decreases reaction
/ increases expression
protein 21420233
D005707 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Gallic Acid inhibits the reaction [TNF protein results in increased expression of CXCR4 mRNA] decreases reaction
/ increases expression
protein 21420233
D005707 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Gallic Acid inhibits the reaction [TNF protein results in increased expression of IL6 mRNA] decreases reaction
/ increases expression
protein 21420233
D005707 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Gallic Acid inhibits the reaction [TNF protein results in increased expression of IL8 mRNA] decreases reaction
/ increases expression
protein 21420233
D005707 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Gallic Acid inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA] decreases reaction
/ increases expression
protein 21420233
D005707 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Gallic Acid inhibits the reaction [TNF protein results in increased expression of VEGFA mRNA] decreases reaction
/ increases expression
protein 21420233
D005707 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Gallic Acid inhibits the reaction [TNF protein results in increased expression of XIAP mRNA] decreases reaction
/ increases expression
protein 21420233
D005707 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Gallic Acid inhibits the reaction [TNF protein results in increased phosphorylation of CHUK protein] decreases reaction
/ increases phosphorylation
protein 21420233
D005707 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Gallic Acid inhibits the reaction [TNF protein results in increased phosphorylation of IKBKB protein] decreases reaction
/ increases phosphorylation
protein 21420233
D005707 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Gallic Acid inhibits the reaction [TNF protein results in increased phosphorylation of MAP2K1 protein] decreases reaction
/ increases phosphorylation
protein 21420233
D005707 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Gallic Acid inhibits the reaction [TNF protein results in increased phosphorylation of MAPK8 protein] decreases reaction
/ increases phosphorylation
protein 21420233
D005707 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Gallic Acid inhibits the reaction [TNF protein results in increased phosphorylation of MAPK9 protein] decreases reaction
/ increases phosphorylation
protein 21420233
D005707 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Gallic Acid inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KA1 protein] decreases reaction
/ increases phosphorylation
protein 21420233
D005707 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Gallic Acid inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KA5 protein] decreases reaction
/ increases phosphorylation
protein 21420233
D005707 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Gallic Acid inhibits the reaction [TNF protein results in increased secretion of IL6 protein] decreases reaction
/ increases secretion
protein 21420233
D005707 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor Gallic Acid inhibits the reaction [TNF protein results in increased secretion of IL8 protein] decreases reaction
/ increases secretion
protein 21420233
D005707 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 Gallic Acid results in decreased expression of TP53 mRNA decreases expression
mRNA 21887735
D005707 7224 TRPC5
TRP5
transient receptor potential cation channel, subfamily C, member 5 Gallic Acid inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]] decreases reaction
/ increases reaction
/ increases transport
protein 21127073
D005707 7224 TRPC5
TRP5
transient receptor potential cation channel, subfamily C, member 5 Gallic Acid inhibits the reaction [Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]] decreases reaction
/ increases reaction
/ increases transport
protein 21127073
D005707 7422 VEGFA
MVCD1
VEGF
VPF
vascular endothelial growth factor A Gallic Acid inhibits the reaction [TNF protein results in increased expression of VEGFA mRNA] decreases reaction
/ increases expression
mRNA 21420233
D005707 331 XIAP
API3
BIRC4
IAP-3
ILP1
MIHA
XLP2
hIAP-3
hIAP3
X-linked inhibitor of apoptosis Gallic Acid inhibits the reaction [TNF protein results in increased expression of XIAP mRNA] decreases reaction
/ increases expression
mRNA 21420233

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (53)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#600807 Asthma, susceptibility to Q13093
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#218800 Crigler-najjar syndrome, type i P22309
#606785 Crigler-najjar syndrome, type ii P22309
#119900 Digital clubbing, isolated congenital P15428
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#133239 Esophageal cancer P04637
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#143500 Gilbert syndrome P22309
#610140 Heart-hand syndrome, slovenian type P02545
#614519 Hemorrhage, intracerebral, susceptibility to; ich P12821
#114550 Hepatocellular carcinoma P08581
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#143860 Hyperchlorhidrosis, isolated O43570
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#147050 Ige responsiveness, atopic; iger Q13093
#614328 Inflammatory skin and bowel disease, neonatal; nisbd P78536
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#211980 Lung cancer P04637
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#612624 Microvascular complications of diabetes, susceptibility to, 3; mvcd3 P12821
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#260500 Papilloma of choroid plexus; cpp P04637
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#614278 Platelet-activating factor acetylhydrolase deficiency; pafad Q13093
#605074 Renal cell carcinoma, papillary, 1; rccp1 P08581
#267430 Renal tubular dysgenesis; rtd P12821
#275210 Restrictive dermopathy, lethal P02545
#600852 Retinitis pigmentosa 17; rp17 P22748
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601367 Stroke, ischemic P12821
P16109
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (68)

KEGG disease name UniProt
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
P04637 (marker)
P08581 (related)
Q16790 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04637 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P04637 (related)
P08581 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00027 Ovarian cancer P04637 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
H00033 Adrenal carcinoma P04637 (related)
H00036 Osteosarcoma P04637 (related)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
P08581 (related)
P35354 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00083 Allograft rejection P12821 (related)
H00575 Renal tubular dysgenesis P12821 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00208 Hyperbilirubinemia P22309 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
Q16637 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)

Diseases related to CTD interactions

16 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D003921 D005707 Diabetes Mellitus, Experimental therapeutic
21078310
D050171 D005707 Dyslipidemias therapeutic
21078310
D005234 D005707 Fatty Liver therapeutic
18571153
D018149 D005707 Glucose Intolerance therapeutic
21078310
D006937 D005707 Hypercholesterolemia therapeutic
18571153
D006943 D005707 Hyperglycemia therapeutic
21078310
D006949 D005707 Hyperlipidemias therapeutic
18571153
D015228 D005707 Hypertriglyceridemia therapeutic
18571153
D015464 D005707 Leukemia, Myelogenous, Chronic, BCR-ABL Positive therapeutic
22245431
D008546 D005707 Melanoma, Experimental therapeutic
19577552
D009069 D005707 Movement Disorders therapeutic
21402136
D009203 D005707 Myocardial Infarction therapeutic
19146839
D009361 D005707 Neoplasm Invasiveness therapeutic
22387266
D009362 D005707 Neoplasm Metastasis therapeutic
22387266
23153558
D012516 D005707 Osteosarcoma therapeutic
22387266
D010182 D005707 Pancreatic Diseases therapeutic
21078310