KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00000982
![]() |
Naringenin
/ (-)-Naringenin |
CHEMBL9352
CHEMBL32571 |
C005273
|
57 / 46 / 40 | 35 / 10 | No. 25 | No. 14 |
![]() |
C00000677
![]() |
Distylin
/ Dihydroquercetin / (2R,3R)-Taxifolin |
CHEMBL66
CHEMBL9249 CHEMBL337309 CHEMBL1492383 |
C003377
|
65 / 41 / 37 | 29 / 1 | No. 42 | No. 14 |
![]() |
C00007234
![]() |
Katuranin
/ (+)-Aromadendrin / (+)-Dihydrokaempferol / (2R,3R)-2,3-Dihydro-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL9323
CHEMBL1933859 |
C080220
|
4 / 3 / 3 | No. 42 | No. 14 |
![]() |
|
C00000856
![]() |
4-Hydroxybenzoic acid
/ p-Hydroxybenzoic acid |
CHEMBL441343
|
C038193
|
21 / 7 / 16 | 2 / 1 | No. 817 | No. 81 |
![]() |
C00002647
![]() |
Gallic acid
|
CHEMBL288114
|
D005707
|
42 / 53 / 68 | 52 / 16 | No. 817 | No. 81 |
![]() |
C00000152
![]() |
p-Coumaric acid
|
CHEMBL66879
CHEMBL2336752 |
C032171
|
23 / 13 / 18 | 6 / 1 | No. 904 | No. 6 |
![]() |
C00000615
![]() |
Caffeic acid
|
CHEMBL145
CHEMBL1320034 |
68 / 64 / 63 | No. 904 | No. 6 |
![]() |
||
C00002682
![]() |
Vanillic acid
/ 3-Methoxy-4-hydroxybenzoic acid |
CHEMBL120568
|
D014641
|
5 / 3 / 3 | 5 / 0 | No. 1073 |
![]() |
|
C00002743
![]() |
Ferulic acid
/ 3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid |
CHEMBL32749
|
C004999
|
110 / 52 / 40 | 16 / 6 | No. 1366 | No. 6 |
![]() |
C00024788
![]() |
Equisetin
/ (-)-Equisetin |
C024509
|
No. 2181 |
![]() |
||||
C00002353
![]() |
Palustrine
|
C099474
|
No. 5169 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P03372 | Estrogen receptor | NR3A1 | C00000152 C00000615 C00000982 C00002647 C00002682 C00002743 | 1 / 1 |
P22748 | Carbonic anhydrase 4 | Lyase | C00000152 C00000615 C00000856 C00002647 C00002743 | 1 / 1 |
Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00000152 C00000615 C00000856 C00002647 C00002743 | 0 / 0 |
O43570 | Carbonic anhydrase 12 | Lyase | C00000152 C00000615 C00000856 C00002647 C00002743 | 1 / 2 |
P15121 | Aldose reductase | Enzyme | C00000152 C00000615 C00000982 C00002647 C00002682 | 0 / 0 |
P00915 | Carbonic anhydrase 1 | Lyase | C00000152 C00000615 C00000856 C00002647 C00002743 | 0 / 0 |
P43166 | Carbonic anhydrase 7 | Lyase | C00000152 C00000615 C00000856 C00002647 C00002743 | 0 / 0 |
P23280 | Carbonic anhydrase 6 | Lyase | C00000152 C00000615 C00000856 C00002647 C00002743 | 0 / 0 |
P07451 | Carbonic anhydrase 3 | Lyase | C00000152 C00000615 C00000856 C00002647 C00002743 | 0 / 0 |
P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00000152 C00000615 C00000856 C00002647 C00002743 | 0 / 0 |
Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00000152 C00000615 C00000856 C00002647 C00002743 | 0 / 0 |
Q16790 | Carbonic anhydrase 9 | Lyase | C00000152 C00000615 C00000856 C00002647 C00002743 | 0 / 1 |
P00918 | Carbonic anhydrase 2 | Lyase | C00000152 C00000615 C00000856 C00002647 C00002743 | 1 / 2 |
P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000152 C00000615 C00000982 C00002647 C00002743 | 0 / 3 |
P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000615 C00000677 C00000982 C00002743 | 0 / 0 |
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000615 C00000677 C00000982 C00002743 | 1 / 0 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000615 C00000677 C00000982 C00002743 | 0 / 1 |
P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000615 C00000677 C00000982 C00002743 | 0 / 1 |
P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00000615 C00000677 C00000982 C00002743 | 1 / 1 |
Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000615 C00000677 C00000982 C00002647 | 3 / 3 |
Q13093 | Platelet-activating factor acetylhydrolase | Enzyme | C00000152 C00000615 C00002647 C00002743 | 3 / 0 |
P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000152 C00000615 C00000856 C00002743 | 1 / 8 |
P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000615 C00000677 C00000982 C00002743 | 1 / 1 |
P28482 | Mitogen-activated protein kinase 1 | Erk | C00000615 C00000677 C00002647 C00002743 | 0 / 0 |
O75496 | Geminin | Unclassified protein | C00000677 C00000982 C00002743 C00007234 | 0 / 0 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000615 C00000677 C00002647 C00002743 | 0 / 0 |
P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00000982 C00002647 C00002743 | 5 / 1 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00000615 C00000677 C00002647 | 4 / 3 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00000615 C00000677 C00002647 | 0 / 0 |
P03956 | Interstitial collagenase | M10A | C00000615 C00000677 C00002743 | 0 / 1 |
P04150 | Glucocorticoid receptor | NR3C1 | C00000982 C00002647 C00002743 | 0 / 1 |
Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000615 C00000677 C00002647 | 0 / 0 |
P41143 | Delta-type opioid receptor | Opioid receptor | C00000677 C00000982 C00002743 | 0 / 0 |
P14679 | Tyrosinase | Oxidoreductase | C00000152 C00000615 C00002743 | 4 / 2 |
Q8TDS4 | Hydroxycarboxylic acid receptor 2 | Hydroxycarboxylic acid receptor | C00000152 C00000615 C00002743 | 0 / 0 |
P36888 | Receptor-type tyrosine-protein kinase FLT3 | Pdgfr | C00000677 C00000982 C00007234 | 1 / 1 |
P14780 | Matrix metalloproteinase-9 | M10A | C00000615 C00000677 C00002743 | 2 / 2 |
Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00000615 C00000982 C00002647 | 1 / 1 |
O00255 | Menin | Unclassified protein | C00000615 C00000677 C00000982 | 2 / 5 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000615 C00000677 C00000982 | 1 / 2 |
P41145 | Kappa-type opioid receptor | Opioid receptor | C00000677 C00000982 C00002743 | 0 / 0 |
P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00000615 C00000677 C00002647 | 0 / 0 |
P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000615 C00000677 C00002647 | 2 / 2 |
Q9UNA4 | DNA polymerase iota | Enzyme | C00000677 C00000982 C00002682 | 0 / 0 |
P35372 | Mu-type opioid receptor | Opioid receptor | C00000677 C00000982 C00002743 | 0 / 0 |
P00352 | Retinal dehydrogenase 1 | Enzyme | C00000615 C00002647 | 0 / 0 |
O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00000615 C00002647 | 0 / 0 |
P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00000982 C00002743 | 3 / 0 |
P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000615 C00000982 | 0 / 0 |
P24298 | Alanine aminotransferase 1 | Enzyme | C00000615 C00000677 | 0 / 0 |
P17516 | Aldo-keto reductase family 1 member C4 | Enzyme | C00000152 C00000615 | 1 / 0 |
Q12794 | Hyaluronidase-1 | Enzyme | C00000615 C00002743 | 1 / 2 |
Q16637 | Survival motor neuron protein | Unclassified protein | C00000677 C00002647 | 4 / 1 |
Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00000615 C00000677 | 0 / 0 |
Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00000856 C00000982 | 0 / 0 |
P52895 | Aldo-keto reductase family 1 member C2 | Enzyme | C00000152 C00000615 | 1 / 0 |
O60218 | Aldo-keto reductase family 1 member B10 | Enzyme | C00000152 C00000615 | 0 / 0 |
P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00000615 C00000677 | 0 / 0 |
P51580 | Thiopurine S-methyltransferase | Enzyme | C00000856 C00002682 | 1 / 1 |
P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00000615 C00000677 | 0 / 0 |
P21728 | D(1A) dopamine receptor | Dopamine receptor | C00000677 C00002743 | 0 / 0 |
P22303 | Acetylcholinesterase | Hydrolase | C00000982 C00002743 | 1 / 0 |
Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00000615 C00002743 | 2 / 2 |
O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00000982 C00002743 | 0 / 0 |
Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00000856 C00000982 | 0 / 0 |
Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00000615 C00000677 | 5 / 2 |
Q04828 | Aldo-keto reductase family 1 member C1 | Enzyme | C00000152 C00000615 | 0 / 0 |
Q92887 | Canalicular multispecific organic anion transporter 1 | Unclassified protein | C00000677 C00000982 | 1 / 1 |
P33765 | Adenosine receptor A3 | Adenosine receptor | C00000677 C00002743 | 0 / 0 |
P08253 | 72 kDa type IV collagenase | M10A | C00000615 C00000677 | 1 / 3 |
P06746 | DNA polymerase beta | Enzyme | C00000615 C00000677 | 0 / 0 |
P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00000677 C00000982 | 2 / 0 |
P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00000982 C00007234 | 2 / 2 |
P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00000615 C00002743 | 0 / 0 |
P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00000615 C00000677 | 1 / 1 |
P02545 | Prelamin-A/C | Unclassified protein | C00000615 C00002647 | 11 / 10 |
P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000677 C00007234 | 0 / 0 |
P17252 | Protein kinase C alpha type | Alpha | C00000677 C00002743 | 0 / 0 |
Q92731 | Estrogen receptor beta | NR3A2 | C00000982 C00002743 | 0 / 1 |
P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00000982 C00002743 | 0 / 0 |
P42330 | Aldo-keto reductase family 1 member C3 | Enzyme | C00000152 C00000615 | 0 / 0 |
Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00000615 C00000677 | 0 / 0 |
P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00000677 | 2 / 0 |
P28907 | ADP-ribosyl cyclase 1 | Enzyme | C00000677 | 0 / 1 |
P51649 | Succinate-semialdehyde dehydrogenase, mitochondrial | Oxidoreductase | C00000856 | 1 / 1 |
P16581 | E-selectin | Adhesion | C00002647 | 0 / 0 |
Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00000677 | 0 / 0 |
P04278 | Sex hormone-binding globulin | Secreted protein | C00000982 | 0 / 0 |
Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00000982 | 0 / 0 |
P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00002743 | 0 / 0 |
P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00002743 | 0 / 0 |
P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00002743 | 1 / 1 |
P39900 | Macrophage metalloelastase | M10A | C00000677 | 0 / 0 |
P39748 | Flap endonuclease 1 | Enzyme | C00000677 | 0 / 0 |
Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00002647 | 0 / 0 |
P42858 | Huntingtin | Unclassified protein | C00002682 | 1 / 1 |
P16152 | Carbonyl reductase [NADPH] 1 | Enzyme | C00000982 | 0 / 0 |
P04406 | Glyceraldehyde-3-phosphate dehydrogenase | Enzyme | C00002647 | 0 / 0 |
O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00000856 | 0 / 0 |
P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00002743 | 0 / 0 |
P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00002743 | 0 / 0 |
P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00002743 | 0 / 0 |
P21917 | D(4) dopamine receptor | Dopamine receptor | C00002743 | 0 / 0 |
P30988 | Calcitonin receptor | Calcitonin receptor | C00002743 | 0 / 0 |
P35462 | D(3) dopamine receptor | Dopamine receptor | C00002743 | 1 / 0 |
P27361 | Mitogen-activated protein kinase 3 | Erk | C00002743 | 0 / 0 |
P62158 | Calmodulin | Unclassified protein | C00000982 | 1 / 0 |
P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00002743 | 0 / 0 |
P29274 | Adenosine receptor A2a | Adenosine receptor | C00002743 | 0 / 0 |
P25101 | Endothelin-1 receptor | Endothelin receptor | C00002743 | 0 / 0 |
P30411 | B2 bradykinin receptor | Bradykinin receptor | C00002743 | 0 / 0 |
P10145 | Interleukin-8 | Secreted protein | C00002647 | 0 / 0 |
P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00002743 | 1 / 0 |
P29466 | Caspase-1 | C14 | C00002743 | 0 / 0 |
P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00002743 | 0 / 0 |
P08311 | Cathepsin G | S1A | C00002743 | 0 / 0 |
Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00002743 | 1 / 0 |
Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | Tyr | C00000615 | 4 / 2 |
P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00002743 | 0 / 0 |
Q9Y253 | DNA polymerase eta | Enzyme | C00000677 | 1 / 1 |
Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00002743 | 0 / 0 |
Q9NPD5 | Solute carrier organic anion transporter family member 1B3 | Electrochemical transporter | C00000982 | 1 / 0 |
P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00000677 | 0 / 0 |
O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00000982 | 0 / 0 |
P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00002743 | 0 / 0 |
P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00002743 | 2 / 0 |
P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00002743 | 0 / 0 |
P14416 | D(2) dopamine receptor | Dopamine receptor | C00002743 | 2 / 0 |
P04062 | Glucosylceramidase | Enzyme | C00000982 | 6 / 4 |
P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00002743 | 0 / 0 |
P31645 | Sodium-dependent serotonin transporter | Serotonin | C00002743 | 2 / 0 |
P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00000982 | 5 / 3 |
P80404 | 4-aminobutyrate aminotransferase, mitochondrial | Transferase | C00000856 | 1 / 1 |
P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00002743 | 5 / 9 |
P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00002743 | 1 / 0 |
Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00000982 | 4 / 4 |
P21452 | Substance-K receptor | Neurokinin receptor | C00002743 | 0 / 0 |
P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00002743 | 0 / 0 |
P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00002743 | 3 / 0 |
P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00002743 | 0 / 0 |
P06280 | Alpha-galactosidase A | Enzyme | C00000615 | 1 / 1 |
P04745 | Alpha-amylase 1 | Enzyme | C00000982 | 0 / 0 |
P45452 | Collagenase 3 | M10A | C00000677 | 1 / 1 |
P11473 | Vitamin D3 receptor | NR1I1 | C00002647 | 2 / 3 |
P08581 | Hepatocyte growth factor receptor | TK tyrosine-protein kinase MET subfamily | C00002647 | 2 / 3 |
P35236 | Tyrosine-protein phosphatase non-receptor type 7 | Tyr | C00000615 | 0 / 0 |
P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00002743 | 1 / 0 |
P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00002743 | 0 / 0 |
P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00002743 | 2 / 1 |
P56817 | Beta-secretase 1 | A1A | C00000677 | 0 / 0 |
P16473 | Thyrotropin receptor | Glycohormone receptor | C00000615 | 3 / 2 |
Q16539 | Mitogen-activated protein kinase 14 | p38 | C00002743 | 0 / 0 |
Q9HAW7 | UDP-glucuronosyltransferase 1-7 | Enzyme | C00000856 | 0 / 0 |
P54132 | Bloom syndrome protein | Enzyme | C00000677 | 1 / 2 |
Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00000982 | 2 / 0 |
Q9GZT9 | Egl nine homolog 1 | Enzyme | C00000615 | 1 / 1 |
O75828 | Carbonyl reductase [NADPH] 3 | Enzyme | C00000982 | 0 / 0 |
P08246 | Neutrophil elastase | S1A | C00002743 | 2 / 1 |
P24864 | G1/S-specific cyclin-E1 | Other cytosolic protein | C00000982 | 0 / 2 |
P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00000982 | 0 / 0 |
P10828 | Thyroid hormone receptor beta | NR1A2 | C00000615 | 3 / 1 |
Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00002743 | 0 / 0 |
P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00002743 | 1 / 0 |
P12821 | Angiotensin-converting enzyme | M2 | C00002647 | 4 / 2 |
P06241 | Tyrosine-protein kinase Fyn | Src | C00002743 | 0 / 0 |
P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00002743 | 0 / 0 |
P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00002743 | 0 / 0 |
Q9UQ49 | Sialidase-3 | Enzyme | C00000856 | 0 / 0 |
P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00002743 | 0 / 0 |
P25103 | Substance-P receptor | Neurokinin receptor | C00002743 | 0 / 0 |
P25105 | Platelet-activating factor receptor | PAF receptor | C00002743 | 0 / 0 |
P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00002743 | 0 / 0 |
P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00002743 | 0 / 0 |
P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00000677 | 0 / 0 |
P78536 | Disintegrin and metalloproteinase domain-containing protein 17 | M12B | C00002647 | 1 / 0 |
P14151 | L-selectin | Adhesion | C00002647 | 0 / 0 |
P16109 | P-selectin | Adhesion | C00002647 | 1 / 0 |
P08183 | Multidrug resistance protein 1 | drug | C00000982 | 1 / 0 |
P37059 | Estradiol 17-beta-dehydrogenase 2 | Enzyme | C00000982 | 0 / 0 |
P51452 | Dual specificity protein phosphatase 3 | Ser_Thr_Tyr | C00000615 | 0 / 0 |
P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00002743 | 0 / 0 |
P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00002743 | 1 / 0 |
P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00000982 | 0 / 0 |
O75164 | Lysine-specific demethylase 4A | Enzyme | C00000615 | 0 / 0 |
P34969 | 5-hydroxytryptamine receptor 7 | Serotonin receptor | C00002743 | 0 / 0 |
O94956 | Solute carrier organic anion transporter family member 2B1 | Unclassified protein | C00000982 | 0 / 0 |
P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00002743 | 0 / 0 |
P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00000856 | 0 / 0 |
Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00002647 | 0 / 0 |
P10275 | Androgen receptor | NR3C4 | C00000982 | 3 / 4 |
P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00002743 | 1 / 1 |
P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00002743 | 0 / 0 |
P30542 | Adenosine receptor A1 | Adenosine receptor | C00002743 | 0 / 0 |
Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00000982 | 0 / 0 |
P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00002743 | 0 / 0 |
P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00002743 | 1 / 1 |
Q9Y6L6 | Solute carrier organic anion transporter family member 1B1 | Electrochemical transporter | C00000982 | 1 / 0 |
P06239 | Tyrosine-protein kinase Lck | Src | C00002743 | 0 / 1 |
Q04760 | Lactoylglutathione lyase | Enzyme | C00000982 | 0 / 0 |
P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00002743 | 0 / 0 |
P08254 | Stromelysin-1 | M10A | C00000677 | 1 / 0 |
P49888 | Estrogen sulfotransferase | Enzyme | C00000982 | 0 / 0 |
P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00002743 | 0 / 0 |
P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00002743 | 0 / 0 |
Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00002743 | 1 / 0 |
P35367 | Histamine H1 receptor | Histamine receptor | C00002743 | 0 / 0 |
P04637 | Cellular tumor antigen p53 | Transcription Factor | C00002647 | 7 / 37 |
P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00000677 | 0 / 0 |
P25021 | Histamine H2 receptor | Histamine receptor | C00002743 | 0 / 0 |
P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00002743 | 1 / 1 |
P33527 | Multidrug resistance-associated protein 1 | drugs | C00000982 | 0 / 0 |
P14061 | Estradiol 17-beta-dehydrogenase 1 | Enzyme | C00000982 | 0 / 0 |
Q13951 | Core-binding factor subunit beta | Unclassified protein | C00000677 | 0 / 1 |
Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00000677 | 1 / 4 |
Q05513 | Protein kinase C zeta type | Iota | C00000677 | 0 / 0 |
Q04759 | Protein kinase C theta type | Delta | C00000677 | 0 / 1 |
Q02156 | Protein kinase C epsilon type | Eta | C00000677 | 0 / 0 |
O94806 | Serine/threonine-protein kinase D3 | Pkd | C00000677 | 0 / 0 |
Q05655 | Protein kinase C delta type | Delta | C00000677 | 0 / 0 |
P05129 | Protein kinase C gamma type | Alpha | C00000677 | 1 / 1 |
P05771 | Protein kinase C beta type | Alpha | C00000677 | 0 / 0 |
P24723 | Protein kinase C eta type | Eta | C00000677 | 1 / 0 |
P41743 | Protein kinase C iota type | Iota | C00000677 | 0 / 0 |
Q15139 | Serine/threonine-protein kinase D1 | Pkd | C00000677 | 0 / 0 |
P07900 | Heat shock protein HSP 90-alpha | Other cytosolic protein | C00000615 | 0 / 0 |
P08238 | Heat shock protein HSP 90-beta | Other cytosolic protein | C00000615 | 0 / 0 |
P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00002743 | 0 / 1 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
6817 | SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) |
C00000152
C00000856
C00000982
C00002647
|
5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00000152
C00002647
C00002743
|
1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00000152
C00000982
C00002743
|
1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00000152
C00000982
C00002743
|
54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) |
C00000982
C00002682
C00002743
|
54577 | UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G | UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) |
C00000982
C00002682
C00002743
|
54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) |
C00000982
C00002682
C00002743
|
4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00000677
C00000982
|
596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00000982
C00002647
|
207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00000982
C00002647
|
3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00000982
C00002647
|
836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00000982
C00002647
|
54659 | UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C | UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) |
C00002682
C00002743
|
7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00000982
C00002647
|
7299 | TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 | tyrosinase (EC:1.14.18.1) |
C00000152
C00002743
|
7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00000982
C00002647
|
5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00002647
C00002743
|
5599 | MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c | mitogen-activated protein kinase 8 (EC:2.7.11.24) |
C00000677
C00002647
|
5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00002647
C00002743
|
338 | APOB, FLDB, LDLCQ4 | apolipoprotein B |
C00000677
C00002647
|
4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) |
C00000152
C00002682
|
1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00002647
C00002743
|
1027 | CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
C00002647
|
6772 | STAT1, CANDF7, ISGF-3, STAT91 | signal transducer and activator of transcription 1, 91kDa |
C00000677
|
7187 | TRAF3, CAP-1, CAP1, CD40bp, CRAF1, IIAE5, LAP1 | TNF receptor-associated factor 3 |
C00000677
|
7296 | TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR | thioredoxin reductase 1 (EC:1.8.1.9) |
C00000677
|
7498 | XDH, XO, XOR | xanthine dehydrogenase (EC:1.17.1.4 1.17.3.2) |
C00000677
|
7507 | XPA, XP1, XPAC | xeroderma pigmentosum, complementation group A |
C00000677
|
7518 | XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
C00000677
|
23621 | BACE1, ASP2, BACE, HSPC104 | beta-site APP-cleaving enzyme 1 (EC:3.4.23.46) |
C00002743
|
595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00002743
|
5155 | PDGFB, IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis | platelet-derived growth factor beta polypeptide |
C00000677
|
1728 | NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 | NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) |
C00000677
|
4780 | NFE2L2, NRF2 | nuclear factor, erythroid 2-like 2 |
C00000677
|
4547 | MTTP, ABL, MTP | microsomal triglyceride transfer protein |
C00000677
|
3725 | JUN, AP-1, AP1, c-Jun | jun proto-oncogene |
C00000677
|
5742 | PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00002743
|
3458 | IFNG, IFG, IFI | interferon, gamma |
C00000677
|
5925 | RB1, OSRC, RB, p105-Rb, pRb, pp110 | retinoblastoma 1 |
C00002743
|
6319 | SCD, FADS5, MSTP008, SCD1, SCDOS | stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1) |
C00002743
|
3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00000677
|
3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00000677
|
2944 | GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1 | glutathione S-transferase mu 1 (EC:2.5.1.18) |
C00000677
|
9518 | GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB | growth differentiation factor 15 |
C00000677
|
2621 | GAS6, AXLLG, AXSF | growth arrest-specific 6 |
C00000677
|
10257 | ABCC4, EST170205, MOAT-B, MOATB, MRP4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
C00000982
|
10057 | ABCC5, ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
C00000982
|
196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00000982
|
1645 | AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB | aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112) |
C00000982
|
8644 | AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS | aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357) |
C00000982
|
2248 | FGF3, HBGF-3, INT2 | fibroblast growth factor 3 |
C00000677
|
249 | ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP | alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1) |
C00000982
|
405 | ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 | aryl hydrocarbon receptor nuclear translocator |
C00000982
|
8817 | FGF18, FGF-18, ZFGF5 | fibroblast growth factor 18 |
C00000677
|
1950 | EGF, HOMG4, URG | epidermal growth factor |
C00000677
|
842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00000982
|
1588 | CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM | cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00000982
|
1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00000982
|
1559 | CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 | cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00000982
|
1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00000982
|
2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00000982
|
2100 | ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 | estrogen receptor 2 (ER beta) |
C00000982
|
1630 | DCC, CRC18, CRCR1, IGDCC1, MRMV1 | deleted in colorectal carcinoma |
C00000677
|
3757 | KCNH2, ERG1, HERG, HERG1, Kv11.1, LQT2, SQT1 | potassium voltage-gated channel, subfamily H (eag-related), member 2 |
C00000982
|
5444 | PON1, ESA, MVCD5, PON | paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) |
C00000982
|
6566 | SLC16A1, HHF7, MCT, MCT1 | solute carrier family 16 (monocarboxylate transporter), member 1 |
C00000982
|
6513 | SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED | solute carrier family 2 (facilitated glucose transporter), member 1 |
C00000982
|
1571 | CYP2E1, CPE1, CYP2E, P450-J, P450C2E | cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) |
C00000677
|
6818 | SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1) |
C00000982
|
993 | CDC25A, CDC25A2 | cell division cycle 25A (EC:3.1.3.48) |
C00000677
|
8900 | CCNA1 | cyclin A1 |
C00000677
|
54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) |
C00000982
|
54600 | UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I | UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) |
C00000982
|
7366 | UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 | UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) |
C00000982
|
335 | APOA1 | apolipoprotein A-I |
C00000677
|
3952 | LEP, LEPD, OB, OBS | leptin |
C00000856
|
5243 | ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) |
C00002647
|
25 | ABL1, ABL, JTK7, bcr/abl, c-ABL, p150, v-abl | c-abl oncogene 1, non-receptor tyrosine kinase (EC:2.7.10.2) |
C00002647
|
472 | ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1 | ataxia telangiectasia mutated (EC:2.7.11.1) |
C00002647
|
545 | ATR, FCTCS, FRP1, MEC1, SCKL, SCKL1 | ataxia telangiectasia and Rad3 related (EC:2.7.11.1) |
C00002647
|
581 | BAX, BCL2L4 | BCL2-associated X protein |
C00002647
|
613 | BCR, ALL, BCR1, CML, D22S11, D22S662, PHL | breakpoint cluster region (EC:2.7.11.1) |
C00002647
|
841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00002647
|
898 | CCNE1, CCNE | cyclin E1 |
C00002647
|
998 | CDC42, CDC42Hs, G25K | cell division cycle 42 |
C00002647
|
5921 | RASA1, CM-AVM, CMAVM, GAP, PKWS, RASA, RASGAP, p120GAP, p120RASGAP | RAS p21 protein activator (GTPase activating protein) 1 |
C00000677
|
1147 | CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16 | conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) |
C00002647
|
7852 | CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM | chemokine (C-X-C motif) receptor 4 |
C00002647
|
54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00002647
|
356 | FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 | Fas ligand (TNF superfamily, member 6) |
C00002647
|
2551 | GABPA, E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A, RCH04A07 | GA binding protein transcription factor, alpha subunit 60kDa |
C00002647
|
2885 | GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2 | growth factor receptor-bound protein 2 |
C00002647
|
3551 | IKBKB, IKK-beta, IKK2, IKKB, NFKBIKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) |
C00002647
|
3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00002647
|
3949 | LDLR, FH, FHC, LDLCQ2 | low density lipoprotein receptor |
C00002647
|
5604 | MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1 | mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) |
C00002647
|
5601 | MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK | mitogen-activated protein kinase 9 (EC:2.7.11.24) |
C00002647
|
4255 | MGMT | O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63) |
C00002647
|
4313 | MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) |
C00002647
|
4316 | MMP7, MMP-7, MPSL1, PUMP-1 | matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23) |
C00002647
|
4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00002647
|
4793 | NFKBIB, IKBB, TRIP9 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
C00002647
|
5578 | PRKCA, AAG6, PKC-alpha, PKCA, PRKACA | protein kinase C, alpha (EC:2.7.11.13) |
C00002647
|
5591 | PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350 | protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1) |
C00002647
|
5879 | RAC1, Rac-1, TC-25, p21-Rac1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) |
C00002647
|
19412 |
C00002647
|
||
5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00002647
|
387 | RHOA, ARH12, ARHA, RHO12, RHOH12 | ras homolog family member A |
C00002647
|
388 | RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6 | ras homolog family member B |
C00002647
|
6195 | RPS6KA1, HU-1, MAPKAPK1A, RSK, RSK1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1) |
C00002647
|
9252 | RPS6KA5, MSK1, MSPK1, RLPK | ribosomal protein S6 kinase, 90kDa, polypeptide 5 (EC:2.7.11.1) |
C00002647
|
6622 | SNCA, NACP, PARK1, PARK4, PD1 | synuclein, alpha (non A4 component of amyloid precursor) |
C00002647
|
7224 | TRPC5, TRP5 | transient receptor potential cation channel, subfamily C, member 5 |
C00002647
|
7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00002647
|
331 | XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 | X-linked inhibitor of apoptosis |
C00002647
|
OMIM | preferred title | UniProt |
---|---|---|
#300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
#614279 | 46,xy sex reversal 8; srxy8 |
P17516
P52895 |
#100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
#202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
#103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
#203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
#606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
#103780 | Alcohol dependence |
P08172
P14416 P31645 |
#614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
#300068 | Androgen insensitivity syndrome; ais |
P10275
|
#312300 | Androgen insensitivity, partial; pais |
P10275
|
#613546 | Aromatase deficiency |
P11511
|
#139300 | Aromatase excess syndrome; aexs |
P11511
|
#600807 | Asthma, susceptibility to |
Q13093
|
#614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
#601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
#614490 | Blood group, junior system; jr |
Q9UNQ0
|
#210900 | Bloom syndrome; blm |
P54132
|
#602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
%606641 | Body mass index; bmi |
P37231
|
#300615 | Brunner syndrome |
P21397
|
#115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
#212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
#609338 | Carotid intimal medial thickness 1 |
P37231
|
#118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
#605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
#118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
#114500 | Colorectal cancer; crc |
P18054
|
#614466 | Coronary heart disease, susceptibility to, 6; chds6 |
P08254
|
#218800 | Crigler-najjar syndrome, type i |
P22309
P22310 |
#606785 | Crigler-najjar syndrome, type ii |
P22309
P22310 |
#162800 | Cyclic neutropenia |
P08246
|
#612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
#119900 | Digital clubbing, isolated congenital |
P15428
|
#609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#237500 | Dubin-johnson syndrome; djs |
Q92887
|
#181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
#609820 | Erythrocytosis, familial, 3; ecyt3 |
Q9GZT9
|
#133239 | Esophageal cancer |
P04637
P18054 |
#615363 | Estrogen resistance; estrr |
P03372
|
#301500 | Fabry disease |
P06280
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#613163 | Gaba-transaminase deficiency |
P80404
|
#613659 | Gastric cancer |
P04626
|
#137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
#608013 | Gaucher disease, perinatal lethal |
P04062
|
#230800 | Gaucher disease, type i |
P04062
|
#230900 | Gaucher disease, type ii |
P04062
|
#231000 | Gaucher disease, type iii |
P04062
|
#231005 | Gaucher disease, type iiic |
P04062
|
#231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
#143500 | Gilbert syndrome |
P22309
P22310 |
#137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
#231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
#137760 | Glaucoma, primary open angle; poag |
Q16678
|
#137800 | Glioma susceptibility 1; glm1 |
P04626
P37231 |
#232300 | Glycogen storage disease ii |
P10253
|
#139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#610140 | Heart-hand syndrome, slovenian type |
P02545
|
#614519 | Hemorrhage, intracerebral, susceptibility to; ich |
P12821
|
#114550 | Hepatocellular carcinoma |
P08581
|
#609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
#143100 | Huntington disease; hd |
P42858
|
#176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
#237450 | Hyperbilirubinemia, rotor type; hblrr |
Q9NPD5
Q9Y6L6 |
#237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
#143860 | Hyperchlorhidrosis, isolated |
O43570
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#603373 | Hyperthyroidism, familial gestational |
P16473
|
#609152 | Hyperthyroidism, nonautoimmune |
P16473
|
#145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
#259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
#275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
#147050 | Ige responsiveness, atopic; iger |
Q13093
|
#612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
#614328 | Inflammatory skin and bowel disease, neonatal; nisbd |
P78536
|
#603932 | Intervertebral disc disease; idd |
P14780
|
#607785 | Juvenile myelomonocytic leukemia; jmml |
Q06124
|
#151100 | Leopard syndrome 1 |
Q06124
|
#601626 | Leukemia, acute myeloid; aml |
P36888
|
#151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
#151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
#604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
#613688 | Long qt syndrome 2; lqt2 |
Q12809
|
#211980 | Lung cancer |
P00533
P04626 P04637 |
#608516 | Major depressive disorder; mdd |
P08172
|
#248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
#300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
%300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
#300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
#156250 | Metachondromatosis; metcds |
Q06124
|
#613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
#612624 | Microvascular complications of diabetes, susceptibility to, 3; mvcd3 |
P12821
|
#601492 | Mucopolysaccharidosis, type ix; mps9 |
Q12794
|
#259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
#613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
#159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
#607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
#159900 | Myoclonic dystonia |
P14416
|
#162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
#202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
#163950 | Noonan syndrome 1; ns1 |
Q06124
|
#601665 | Obesity |
P32245
P37231 |
#164230 | Obsessive-compulsive disorder; ocd |
P31645
|
#604715 | Orthostatic intolerance |
P23975
|
#259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
#167000 | Ovarian cancer |
P04626
|
#260500 | Papilloma of choroid plexus; cpp |
P04637
|
#168600 | Parkinson disease, late-onset; pd |
P04062
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
#604229 | Peters anomaly |
Q16678
|
#172700 | Pick disease of brain |
P10636
|
#601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
#614278 | Platelet-activating factor acetylhydrolase deficiency; pafad |
Q13093
|
#605074 | Renal cell carcinoma, papillary, 1; rccp1 |
P08581
|
#267430 | Renal tubular dysgenesis; rtd |
P12821
|
#607276 | Resting heart rate, variation in |
P08588
|
#275210 | Restrictive dermopathy, lethal |
P02545
|
#600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
#604906 | Schizophrenia 9; sczd9 |
P49798
|
#181500 | Schizophrenia; sczd |
P49798
|
#608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
#609620 | Short qt syndrome 1; sqt1 |
Q12809
|
#601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
#313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
#253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
#253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
#253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
#271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
#605361 | Spinocerebellar ataxia 14; sca14 |
P05129
|
#607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
#602111 | Spondyloepimetaphyseal dysplasia, missouri type |
P45452
|
#275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
#601367 | Stroke, ischemic |
P12821
P16109 P24723 |
#271980 | Succinic semialdehyde dehydrogenase deficiency; ssadhd |
P51649
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#610460 | Thiopurine s-methyltransferase deficiency |
P51580
|
#188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
#274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
#145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
#190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
#138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
#614916 | Ventricular tachycardia, catecholaminergic polymorphic, 4; cpvt4 |
P62158
|
#277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
#610379 | West nile virus, susceptibility to |
P51681
|
#278300 | Xanthinuria, type i |
P47989
|
#278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
#112100 | Yt blood group antigen |
P22303
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
H00021 | Renal cell carcinoma |
O43570
(marker)
P04637 (marker) P08581 (related) Q16790 (marker) |
H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P35354 (related) |
H00018 | Gastric cancer |
P00533
(related)
P04626 (related) P04637 (related) P08581 (related) P24864 (related) |
H00022 | Bladder cancer |
P00533
(related)
P04626 (related) P04637 (related) |
H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) P04637 (related) P08253 (related) |
H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) P24864 (related) |
H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
H00436 | Osteopetrosis |
P00918
(related)
|
H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
H00663 | Restrictive dermopathy |
P02545
(related)
|
H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) P04637 (related) Q92731 (marker) |
H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
H00126 | Gaucher disease |
P04062
(related)
|
H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
P11511 (related) |
H00019 | Pancreatic cancer |
P04626
(related)
P04637 (related) P04637 (marker) |
H00027 | Ovarian cancer |
P04626
(related)
P04637 (related) |
H00031 | Breast cancer |
P04626
(related)
P04626 (marker) P04637 (related) |
H00046 | Cholangiocarcinoma |
P04626
(related)
P04637 (related) P08581 (related) P35354 (related) |
H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
P28907 (marker) |
H00006 | Hairy-cell leukemia |
P04637
(related)
|
H00008 | Burkitt lymphoma |
P04637
(related)
|
H00009 | Adult T-cell leukemia |
P04637
(related)
|
H00010 | Multiple myeloma |
P04637
(related)
|
H00013 | Small cell lung cancer |
P04637
(related)
|
H00014 | Non-small cell lung cancer |
P04637
(related)
|
H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P08253 (related) P14780 (related) P35354 (related) |
H00029 | Vulvar cancer |
P04637
(related)
|
H00032 | Thyroid cancer |
P04637
(related)
P37231 (related) |
H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
H00038 | Malignant melanoma |
P04637
(related)
P14679 (marker) |
H00039 | Basal cell carcinoma |
P04637
(related)
|
H00040 | Squamous cell carcinoma |
P04637
(related)
|
H00041 | Kaposi's sarcoma |
P04637
(related)
|
H00044 | Cancer of the anal canal |
P04637
(related)
|
H00047 | Gallbladder cancer |
P04637
(related)
|
H00048 | Hepatocellular carcinoma |
P04637
(related)
|
H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
H01007 | Choroid plexus papilloma |
P04637
(related)
|
H00063 | Spinocerebellar ataxia (SCA) |
P05129
(related)
Q9NUW8 (related) |
H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
H00125 | Fabry disease |
P06280
(related)
|
H00079 | Asthma |
P07550
(related)
|
H00100 | Neutropenic disorders |
P08246
(related)
|
H00472 | Torg-Winchester syndrome |
P08253
(related)
|
H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
H00024 | Prostate cancer |
P10275
(related)
|
H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
H00342 | Tuberculosis |
P11473
(related)
|
H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
H00794 | Aromatase excess syndrome |
P11511
(related)
|
H01205 | Coumarin resistance |
P11712
(related)
|
H00083 | Allograft rejection |
P12821
(related)
|
H00575 | Renal tubular dysgenesis |
P12821
(related)
|
H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
H00479 | Metaphyseal dysplasias |
P14780
(related)
P45452 (related) |
H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
H01269 | Congenital hyperthyroidism |
P16473
(related)
|
H00548 | Brunner syndrome |
P21397
(related)
|
H00208 | Hyperbilirubinemia |
P22309
(related)
Q92887 (related) |
H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
H00003 | Acute myeloid leukemia (AML) |
P36888
(related)
Q01196 (related) Q01196 (marker) Q13951 (marker) |
H00409 | Type II diabetes mellitus |
P37231
(related)
|
H00059 | Huntington's disease (HD) |
P42858
(related)
|
H00192 | Xanthinuria |
P47989
(related)
|
H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
Q99714 (related) |
H00964 | Thiopurine S-methyltransferase deficiency (TPMT deficiency) |
P51580
(related)
|
H00835 | Succinic semialdehyde dehydrogenase (SSADH) deficiency |
P51649
(related)
|
H00094 | DNA repair defects |
P54132
(related)
|
H00296 | Defects in RecQ helicases |
P54132
(related)
|
H01257 | GABA-transaminase deficiency |
P80404
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00408 | Type I diabetes mellitus |
Q04759
(related)
|
H00523 | Noonan syndrome and related disorders |
Q06124
(related)
|
H01018 | Metachondromatosis |
Q06124
(related)
|
H00133 | Mucopolysaccharidosis type IX (MPS9) |
Q12794
(related)
|
H00421 | Mucopolysaccharidosis (MPS) |
Q12794
(related)
|
H00720 | Long QT syndrome |
Q12809
(related)
|
H00725 | Short QT syndrome |
Q12809
(related)
|
H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
H00612 | Primary open angle glaucoma |
Q16678
(related)
|
H01075 | Peters anomaly |
Q16678
(related)
|
H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
H00236 | Congenital polycythemia |
Q9GZT9
(related)
|
H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
MESH or OMIM | name |
KNApSAcK
metabolite |
---|---|---|
D008106 | Liver Cirrhosis, Experimental |
C00002743
C00000982 |
D009203 | Myocardial Infarction |
C00002743
C00002647 |
D008545 | Melanoma |
C00002743
C00000152 |
D012220 | Rhinitis |
C00000856
|
D006461 | Hemolysis |
C00000677
|
D002252 | Carbon Tetrachloride Poisoning |
C00002743
|
D050197 | Atherosclerosis |
C00002743
|
D000647 | Amnesia |
C00000982
|
D001932 | Brain Neoplasms |
C00000982
|
D009202 | Cardiomyopathies |
C00000982
|
D056486 | Drug-Induced Liver Injury |
C00000982
|
D064420 | Drug-Related Side Effects and Adverse Reactions |
C00000982
|
D007674 | Kidney Diseases |
C00000982
|
D008107 | Liver Diseases |
C00000982
|
D009369 | Neoplasms |
C00000982
|
D009374 | Neoplasms, Experimental |
C00000982
|
D007249 | Inflammation |
C00002743
|
D003921 | Diabetes Mellitus, Experimental |
C00002647
|
D050171 | Dyslipidemias |
C00002647
|
D005234 | Fatty Liver |
C00002647
|
D018149 | Glucose Intolerance |
C00002647
|
D006937 | Hypercholesterolemia |
C00002647
|
D006943 | Hyperglycemia |
C00002647
|
D006949 | Hyperlipidemias |
C00002647
|
D015228 | Hypertriglyceridemia |
C00002647
|
D015464 | Leukemia, Myelogenous, Chronic, BCR-ABL Positive |
C00002647
|
D008546 | Melanoma, Experimental |
C00002647
|
D009069 | Movement Disorders |
C00002647
|
D009361 | Neoplasm Invasiveness |
C00002647
|
D009362 | Neoplasm Metastasis |
C00002647
|
D012516 | Osteosarcoma |
C00002647
|
D010182 | Pancreatic Diseases |
C00002647
|