Species

KNApSAcK Entry

Organism name Eugenia jambolana
Genus Eugenia
Family Myrtaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Syzygium cumini
Linked NCBI taxonomy ID 260142
Linked level species

Family

Family in NCBI taxonomy Myrtaceae
ID 3931

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (19)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00006738 External link 512 Malvidin 3-laminaribioside
No. 1 No. 15
C00013564 External link 512 Delphinidin 3-gentiobioside
No. 1 No. 15
C00006726 External link 512 Petunidin 3-gentiobioside
No. 1 No. 15
C00011156 External link 512 Mearnsetin 3-O-(4''-O-acetyl)-alpha-L-rhamnopyranoside
/ 3-[(4-O-Acetyl-6-deoxy-alpha-L-mannopyranosyl)oxy]-2-(3,5-dihydroxy-4-methoxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one
No. 2 No. 15
C00006041 External link 512 yricetin 3-acetylrhamnoside
/ Myricetin 3-O-(3''-O-acetyl)-alpha-L-rhamnoside
/ Myricetin 3-O-(4''-acetyl)-alpha-L-rhamnopyranoside
No. 2 No. 15
C00005374 External link 512 Quercetin
CHEMBL82242
CHEMBL479232
CHEMBL1437696
C012526
14 / 2 / 2 2 / 1 No. 2 No. 15
C00005731 External link 512 Myricetin 3-glucuronide
CHEMBL458470
C072578
2 / 0 / 3 No. 2 No. 15
C00001071 External link 512 Myricetin
CHEMBL164
C040015
78 / 70 / 56 39 / 2 No. 3 No. 15
C00004565 External link 512 Kaempferol
/ Nimbecetin
/ Rhamnolutein
/ Pelargidenolon
/ 5,7,4'-Trihydroxyflavonol
/ 3,5,7,4'-Tetrahydroxyflavone
/ 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
CHEMBL150
C006552
76 / 69 / 87 86 / 8 No. 71 No. 15
C00011157 External link 512 Myricetin 3-O-(4''-O-acetyl-2''-O-galloyl)-alpha-L-rhamnopyranoside
/ 3-[[4-O-Acetyl-6-deoxy-2-O-(3,4,5-trihydroxybenzoyl)-alpha-L-mannopyranosyl]oxy]-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one
No. 98
C00002724 External link 512 Heriguard
/ Chlorogenic acid
/ 3-O-Caffeoylquinic acid
CHEMBL284616
CHEMBL230481
CHEMBL249450
CHEMBL1332980
CHEMBL1394423
CHEMBL1419611
CHEMBL1473644
CHEMBL1552319
D002726
30 / 19 / 22 37 / 9 No. 314 No. 6
C00036886 External link 512 Casuarine
/ (+)-Casuarine
No. 677 No. 2
C00002647 External link 512 Gallic acid
CHEMBL288114
D005707
42 / 53 / 68 52 / 16 No. 817 No. 81
C00002671 External link 512 Resorcinol
CHEMBL24147
C031389
21 / 24 / 25 3 / 1 No. 1590 No. 82
C00036887 External link 512 Casuarine 6-O-alpha-D-glucopyranoside
No. 2052
C00011154 External link 512 3-O-Methylellagic acid
CHEMBL564351
No. 2068 No. 81
C00011153 External link 512 Gallogen
/ Ellagic acid
/ Elagostasine
/ Alizarin yellow
CHEMBL6246
D004610
104 / 97 / 100 77 / 9 No. 2068 No. 81
C00011155 External link 512 Nilocitin
/ 2,3-di-O-Galloylglucose
No. 2122
C00030226 External link 512 Eugenin
CHEMBL446974
2 / 0 / 3 No. 2463 No. 15

Human Protein / Gene in interactions

197 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P00352 Retinal dehydrogenase 1 Enzyme C00001071 C00002647 C00002671 C00002724 C00004565 C00005374 0 / 0
P15121 Aldose reductase Enzyme C00001071 C00002647 C00002724 C00004565 C00005374 C00011153 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00001071 C00002647 C00002671 C00002724 C00004565 C00011153 3 / 3
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00001071 C00002647 C00002724 C00004565 C00005731 C00030226 0 / 3
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001071 C00002647 C00002724 C00004565 C00005374 C00011153 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001071 C00002647 C00002724 C00004565 C00005374 C00011153 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00001071 C00002647 C00002724 C00005374 C00011153 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00001071 C00002647 C00002724 C00004565 C00011153 1 / 1
O75164 Lysine-specific demethylase 4A Enzyme C00001071 C00002724 C00004565 C00005374 C00011153 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00001071 C00002647 C00002724 C00011153 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00001071 C00004565 C00005374 C00011153 0 / 0
P02545 Prelamin-A/C Unclassified protein C00002647 C00002671 C00004565 C00011153 11 / 10
P10636 Microtubule-associated protein tau Unclassified protein C00001071 C00002647 C00004565 C00011153 4 / 3
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001071 C00002671 C00002724 C00004565 0 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00001071 C00002647 C00005374 C00011153 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002647 C00002671 C00002724 C00004565 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001071 C00002724 C00004565 C00011153 1 / 1
P39748 Flap endonuclease 1 Enzyme C00001071 C00004565 C00005374 C00011153 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001071 C00002724 C00004565 C00011153 0 / 1
Q9Y253 DNA polymerase eta Enzyme C00001071 C00004565 C00005374 C00011153 1 / 1
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00001071 C00002647 C00004565 C00011153 2 / 2
Q9ULX7 Carbonic anhydrase 14 Lyase C00002647 C00002671 C00011153 0 / 0
P07451 Carbonic anhydrase 3 Lyase C00002647 C00002671 C00011153 0 / 0
O43570 Carbonic anhydrase 12 Lyase C00002647 C00002671 C00011153 1 / 2
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00002647 C00002671 C00011153 0 / 0
P43166 Carbonic anhydrase 7 Lyase C00002647 C00002671 C00011153 0 / 0
O15296 Arachidonate 15-lipoxygenase B Enzyme C00001071 C00004565 C00011153 0 / 0
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr C00001071 C00004565 C00011153 1 / 1
P22748 Carbonic anhydrase 4 Lyase C00002647 C00002671 C00011153 1 / 1
P23280 Carbonic anhydrase 6 Lyase C00002647 C00002671 C00011153 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00002647 C00002724 C00004565 0 / 1
O75496 Geminin Unclassified protein C00002671 C00002724 C00011153 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00001071 C00004565 C00011153 0 / 0
O00255 Menin Unclassified protein C00001071 C00004565 C00011153 2 / 5
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00004565 C00005731 C00030226 0 / 0
P10145 Interleukin-8 Secreted protein C00002647 C00002671 C00002724 0 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00002647 C00004565 C00011153 7 / 37
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00001071 C00004565 C00005374 1 / 1
P00915 Carbonic anhydrase 1 Lyase C00002647 C00002671 C00011153 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00001071 C00004565 C00011153 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00001071 C00002647 C00011153 2 / 3
P00918 Carbonic anhydrase 2 Lyase C00002647 C00002671 C00011153 1 / 2
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001071 C00002724 C00004565 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00002647 C00002671 C00011153 0 / 1
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00001071 C00004565 C00011153 1 / 2
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00002647 C00002671 C00011153 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001071 C00002724 C00004565 1 / 0
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00002671 C00004565 0 / 0
P03372 Estrogen receptor NR3A1 C00002647 C00004565 1 / 1
P12821 Angiotensin-converting enzyme M2 C00002647 C00011153 4 / 2
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 C00001071 C00004565 0 / 0
P11309 Serine/threonine-protein kinase pim-1 Pim C00001071 C00004565 0 / 0
P22303 Acetylcholinesterase Hydrolase C00001071 C00004565 1 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00002647 C00011153 0 / 0
P08581 Hepatocyte growth factor receptor TK tyrosine-protein kinase MET subfamily C00002647 C00011153 2 / 3
P54132 Bloom syndrome protein Enzyme C00001071 C00011153 1 / 2
Q9HC97 G-protein coupled receptor 35 Kynurenic acid receptor C00001071 C00011153 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00001071 C00011153 1 / 0
P04745 Alpha-amylase 1 Enzyme C00001071 C00004565 0 / 0
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00004565 C00011153 1 / 8
P06276 Cholinesterase Hydrolase C00001071 C00004565 0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00001071 C00004565 0 / 0
Q02880 DNA topoisomerase 2-beta Isomerase C00001071 C00011153 0 / 0
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00001071 C00011153 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00001071 C00011153 0 / 0
P12931 Proto-oncogene tyrosine-protein kinase Src Src C00002724 C00011153 0 / 0
P04406 Glyceraldehyde-3-phosphate dehydrogenase Enzyme C00002647 C00011153 0 / 0
P10275 Androgen receptor NR3C4 C00002671 C00004565 3 / 4
P04062 Glucosylceramidase Enzyme C00001071 C00004565 6 / 4
P06746 DNA polymerase beta Enzyme C00001071 C00011153 0 / 0
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 C00001071 C00004565 4 / 4
P14679 Tyrosinase Oxidoreductase C00002671 C00004565 4 / 2
Q13093 Platelet-activating factor acetylhydrolase Enzyme C00002647 C00002724 3 / 0
Q04760 Lactoylglutathione lyase Enzyme C00001071 C00004565 0 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00001071 C00004565 0 / 0
P06213 Insulin receptor TK tyrosine-protein kinase INSR subfamily C00001071 C00011153 5 / 4
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00002724 C00004565 2 / 2
Q92830 Histone acetyltransferase KAT2A Enzyme C00002647 C00011153 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00001071 C00011153 2 / 0
Q99700 Ataxin-2 Unclassified protein C00001071 C00004565 1 / 1
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00001071 C00011153 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00001071 C00011153 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00001071 C00011153 0 / 1
P33527 Multidrug resistance-associated protein 1 drugs C00001071 C00004565 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00004565 C00011153 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00001071 C00011153 0 / 0
Q01196 Runt-related transcription factor 1 Unclassified protein C00001071 C00011153 1 / 4
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00001071 C00005374 0 / 0
Q9Y3R4 Sialidase-2 Enzyme C00001071 C00004565 0 / 0
P98170 E3 ubiquitin-protein ligase XIAP Other cytosolic protein C00004565 1 / 1
Q12791 Calcium-activated potassium channel subunit alpha-1 KCNM, KCa1.x C00004565 1 / 1
Q02763 Angiopoietin-1 receptor Tie C00011153 1 / 1
P15056 Serine/threonine-protein kinase B-raf Raf C00011153 6 / 3
P08107 Heat shock 70 kDa protein 1A/1B Unclassified protein C00011153 0 / 0
P09211 Glutathione S-transferase P Enzyme C00011153 0 / 1
P09923 Intestinal-type alkaline phosphatase Enzyme C00001071 0 / 0
O60285 NUAK family SNF1-like kinase 1 CAMK serine/threonine protein kinase NUAK subfamily C00011153 0 / 0
P05186 Alkaline phosphatase, tissue-nonspecific isozyme Enzyme C00001071 3 / 1
Q05397 Focal adhesion kinase 1 Fak C00011153 0 / 0
P27487 Dipeptidyl peptidase 4 S9B C00004565 0 / 1
Q4U2R8 Solute carrier family 22 member 6 Antiporter C00011153 0 / 0
Q14790 Caspase-8 C14 C00001071 2 / 1
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00001071 0 / 0
P11021 78 kDa glucose-regulated protein Unclassified protein C00011153 0 / 0
O60656 UDP-glucuronosyltransferase 1-9 Enzyme C00002724 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00011153 2 / 0
P54760 Ephrin type-B receptor 4 Eph C00011153 0 / 0
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 C00001071 2 / 2
P68871 Hemoglobin subunit beta Secreted protein C00011153 4 / 4
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00004565 5 / 3
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00011153 5 / 9
P09619 Platelet-derived growth factor receptor beta Pdgfr C00011153 5 / 1
P16581 E-selectin Adhesion C00002647 0 / 0
Q15746 Myosin light chain kinase, smooth muscle Mlck C00001071 1 / 1
P11387 DNA topoisomerase 1 Isomerase C00001071 0 / 0
Q9GZU7 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 Enzyme C00004565 0 / 0
Q96GD4 Aurora kinase B Aur C00011153 0 / 0
P35968 Vascular endothelial growth factor receptor 2 Vegfr C00011153 1 / 0
P18054 Arachidonate 12-lipoxygenase, 12S-type Enzyme C00001071 2 / 0
Q96RI1 Bile acid receptor NR1H4 C00004565 0 / 0
P07237 Protein disulfide-isomerase Enzyme C00005374 0 / 0
P24385 G1/S-specific cyclin-D1 Other cytosolic protein C00011153 1 / 8
P35916 Vascular endothelial growth factor receptor 3 Vegfr C00011153 2 / 1
P10696 Alkaline phosphatase, placental-like Enzyme C00001071 0 / 1
P11802 Cyclin-dependent kinase 4 CMGC serine/threonine protein kinase family C00011153 1 / 3
P00390 Glutathione reductase, mitochondrial Oxidoreductase C00011153 0 / 0
Q15078 Cyclin-dependent kinase 5 activator 1 REG serine/threonine protein kinase family C00004565 0 / 0
P41279 Mitogen-activated protein kinase kinase kinase 8 Ste11 C00011153 0 / 0
Q00535 Cyclin-dependent kinase 5 Cdk5 C00004565 0 / 0
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00004565 2 / 0
Q92887 Canalicular multispecific organic anion transporter 1 Unclassified protein C00001071 1 / 1
P51692 Signal transducer and activator of transcription 5B Unclassified protein C00002724 1 / 1
O00444 Serine/threonine-protein kinase PLK4 PLK serine/threonine protein kinase subfamily C00011153 0 / 0
Q01453 Peripheral myelin protein 22 Unclassified protein C00001071 5 / 2
P78536 Disintegrin and metalloproteinase domain-containing protein 17 M12B C00002647 1 / 0
P08183 Multidrug resistance protein 1 drug C00004565 1 / 0
P51452 Dual specificity protein phosphatase 3 Ser_Thr_Tyr C00011153 0 / 0
Q00534 Cyclin-dependent kinase 6 CMGC serine/threonine protein kinase family C00004565 1 / 0
P53350 Serine/threonine-protein kinase PLK1 PLK serine/threonine protein kinase subfamily C00011153 0 / 0
P68400 Casein kinase II subunit alpha Ck2 C00011153 0 / 0
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00004565 0 / 0
P31749 RAC-alpha serine/threonine-protein kinase Akt C00011153 4 / 1
P14151 L-selectin Adhesion C00002647 0 / 0
P16109 P-selectin Adhesion C00002647 1 / 0
P10828 Thyroid hormone receptor beta NR1A2 C00011153 3 / 1
P37059 Estradiol 17-beta-dehydrogenase 2 Enzyme C00004565 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00002724 3 / 2
P40763 Signal transducer and activator of transcription 3 Transcription Factor C00002724 1 / 2
P07949 Proto-oncogene tyrosine-protein kinase receptor Ret Ret C00011153 9 / 4
P28907 ADP-ribosyl cyclase 1 Enzyme C00001071 0 / 1
Q15046 Lysine--tRNA ligase Enzyme C00001071 2 / 1
Q13315 Serine-protein kinase ATM Atypical serine/threonine protein kinase PIKK subfamily C00011153 1 / 4
O14965 Aurora kinase A Aur C00011153 0 / 0
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00002647 5 / 1
Q8N1Q1 Carbonic anhydrase 13 Lyase C00011153 0 / 0
Q99549 M-phase phosphoprotein 8 Unclassified protein C00001071 0 / 0
P19224 UDP-glucuronosyltransferase 1-6 Enzyme C00002724 0 / 0
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00004565 0 / 0
P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Enzyme C00001071 9 / 1
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00004565 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00011153 1 / 1
P06239 Tyrosine-protein kinase Lck Src C00002724 0 / 1
P08069 Insulin-like growth factor 1 receptor TK tyrosine-protein kinase INSR subfamily C00011153 1 / 3
P35869 Aryl hydrocarbon receptor Transcription Factor C00004565 0 / 0
P48147 Prolyl endopeptidase S9A C00004565 0 / 0
Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A CMGC dual-specificity kinase DYRK1 C00011153 1 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00001071 0 / 0
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00004565 0 / 0
P11142 Heat shock cognate 71 kDa protein Unclassified protein C00011153 0 / 0
O60218 Aldo-keto reductase family 1 member B10 Enzyme C00002724 0 / 0
P31941 DNA dC->dU-editing enzyme APOBEC-3A Enzyme C00001071 0 / 0
P40225 Thrombopoietin Unclassified protein C00001071 1 / 1
P42224 Signal transducer and activator of transcription 1-alpha/beta Unclassified protein C00002724 3 / 3
Q16637 Survival motor neuron protein Unclassified protein C00002647 4 / 1
Q9NPH5 NADPH oxidase 4 Enzyme C00004565 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00011153 1 / 0
Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 Other cytosolic protein C00011153 0 / 0
Q9P1W9 Serine/threonine-protein kinase pim-2 Pim C00005374 0 / 0
P14061 Estradiol 17-beta-dehydrogenase 1 Enzyme C00004565 0 / 0
Q9NSA0 Solute carrier family 22 member 11 Transporter C00011153 0 / 0
O95067 G2/mitotic-specific cyclin-B2 Other cytosolic protein C00004565 0 / 0
P14635 G2/mitotic-specific cyclin-B1 Other cytosolic protein C00004565 0 / 0
P06493 Cyclin-dependent kinase 1 Cdc2 C00004565 0 / 0
Q8WWL7 G2/mitotic-specific cyclin-B3 Other cytosolic protein C00004565 0 / 0
P20248 Cyclin-A2 Other cytosolic protein C00011153 0 / 0
P78396 Cyclin-A1 Other cytosolic protein C00011153 0 / 0
P24941 Cyclin-dependent kinase 2 Cdc2 C00011153 0 / 0
P22694 cAMP-dependent protein kinase catalytic subunit beta Pka C00011153 0 / 0
P17612 cAMP-dependent protein kinase catalytic subunit alpha Pka C00011153 0 / 0
P22612 cAMP-dependent protein kinase catalytic subunit gamma Pka C00011153 0 / 0
P49840 Glycogen synthase kinase-3 alpha Gsk C00004565 0 / 0
Q9UM73 ALK tyrosine kinase receptor TKL serine/threonine protein kinase STKR type 1 subfamily C00011153 1 / 1
P06748 Nucleophosmin Other nuclear protein C00011153 0 / 0
P42345 Serine/threonine-protein kinase mTOR Enzyme C00001071 0 / 0
Q9H0H5 Rac GTPase-activating protein 1 Unclassified protein C00004565 0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00001071 2 / 1
Q9HCT0 Fibroblast growth factor 22 Unclassified protein C00001071 0 / 0

232 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001071 C00004565 C00005374 C00011153
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00001071 C00002647 C00004565 C00011153
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00001071 C00002647 C00002671 C00004565
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00001071 C00002647 C00004565 C00011153
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00001071 C00002647 C00004565
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00001071 C00004565 C00005374
4780 NFE2L2, NRF2 nuclear factor, erythroid 2-like 2 C00001071 C00004565 C00011153
581 BAX, BCL2L4 BCL2-associated X protein C00001071 C00002647 C00004565
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00001071 C00002647 C00011153
3569 IL6, BSF2, HGF, HSF, IFNB2, IL-6 interleukin 6 (interferon, beta 2) C00001071 C00002647 C00004565
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00001071 C00002647 C00004565
54205 CYCS, CYC, HCS, THC4 cytochrome c, somatic C00001071 C00002647 C00004565
5243 ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) C00002647 C00004565
4318 MMP9, CLG4B, GELB, MANDP2, MMP-9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) C00001071 C00002647
891 CCNB1, CCNB cyclin B1 C00001071 C00004565
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00001071 C00011153
8505 PARG, PARG99 poly (ADP-ribose) glycohydrolase (EC:3.2.1.143) C00001071 C00011153
1031 CDKN2C, INK4C, p18, p18-INK4C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) C00001071 C00004565
3091 HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) C00001071 C00011153
1147 CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16 conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) C00002647 C00004565
54576 UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) C00002724 C00004565
54577 UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) C00002724 C00004565
54659 UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) C00002724 C00004565
472 ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1 ataxia telangiectasia mutated (EC:2.7.11.1) C00002647 C00004565
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00001071 C00004565
54575 UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) C00002724 C00004565
6649 SOD3, EC-SOD superoxide dismutase 3, extracellular (EC:1.15.1.1) C00002724 C00011153
7161 TP73, P73 tumor protein p73 C00001071 C00004565
8626 TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L tumor protein p63 C00001071 C00004565
9540 TP53I3, PIG3 tumor protein p53 inducible protein 3 C00001071 C00004565
2099 ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 estrogen receptor 1 C00002671 C00004565
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00002647 C00004565
2203 FBP1, FBP fructose-1,6-bisphosphatase 1 (EC:3.1.3.11) C00001071 C00004565
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00002647 C00011153
7039 TGFA, TFGA transforming growth factor, alpha C00002671 C00004565
7019 TFAM, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3 transcription factor A, mitochondrial C00004565 C00011153
6513 SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED solute carrier family 2 (facilitated glucose transporter), member 1 C00001071 C00004565
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00002647 C00004565
8000 PSCA, PRO232 prostate stem cell antigen C00001071 C00004565
5241 PGR, NR3C3, PR progesterone receptor C00002724 C00004565
9970 NR1I3, CAR, CAR1, MB67 nuclear receptor subfamily 1, group I, member 3 C00004565 C00011153
3082 HGF, DFNB39, F-TCF, HGFB, HPTA, SF hepatocyte growth factor (hepapoietin A; scatter factor) C00001071 C00004565
4313 MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) C00002647 C00011153
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00004565 C00011153
4233 MET, AUTS9, HGFR, RCCP2, c-Met met proto-oncogene (EC:2.7.10.1) C00001071 C00004565
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00002647 C00004565
4363 ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 C00001071 C00004565
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00002647 C00004565
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00002647
3725 JUN, AP-1, AP1, c-Jun jun proto-oncogene C00004565
3567 IL5, EDF, IL-5, TRF interleukin 5 (colony-stimulating factor, eosinophil) C00004565
3565 IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4 interleukin 4 C00004565
110357 C00004565
4502 MT2A, MT2 metallothionein 2A C00004565
4586 MUC5AC, MUC5, TBM, leB mucin 5AC, oligomeric mucus/gel-forming C00004565
8202 NCOA3, ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP nuclear receptor coactivator 3 (EC:2.3.1.48) C00004565
3383 ICAM1, BB2, CD54, P3.58 intercellular adhesion molecule 1 C00004565
4792 NFKBIA, IKBA, MAD-3, NFKBI nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha C00004565
4843 NOS2, HEP-NOS, INOS, NOS, NOS2A nitric oxide synthase 2, inducible (EC:1.14.13.39) C00004565
8856 NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR nuclear receptor subfamily 1, group I, member 2 C00004565
3043 HBB, CD113t-C, beta-globin hemoglobin, beta C00004565
3014 H2AFX, H2A.X, H2A/X, H2AX H2A histone family, member X C00004565
10891 PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha C00004565
2950 GSTP1, DFN7, FAEES3, GST3, GSTP, PI glutathione S-transferase pi 1 (EC:2.5.1.18) C00004565
2938 GSTA1, GST2, GSTA1-1, GTH1 glutathione S-transferase alpha 1 (EC:2.5.1.18) C00004565
6119 RPA3, REPA3 replication protein A3, 14kDa C00004565
2810 SFN, YWHAS stratifin C00004565
9687 GREB1 growth regulation by estrogen in breast cancer 1 C00004565
6773 STAT2, ISGF-3, P113, STAT113 signal transducer and activator of transcription 2, 113kDa C00004565
2729 GCLC, GCL, GCS, GLCL, GLCLC glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) C00004565
7031 TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 trefoil factor 1 C00004565
4616 GADD45B, GADD45BETA, MYD118 growth arrest and DNA-damage-inducible, beta C00004565
2353 FOS, AP-1, C-FOS, p55 FBJ murine osteosarcoma viral oncogene homolog C00004565
2100 ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 estrogen receptor 2 (ER beta) C00004565
1734 DIO2, 5DII, D2, DIOII, SelY, TXDI2 deiodinase, iodothyronine, type II (EC:1.97.1.10) C00004565
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00004565
1559 CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) C00004565
7352 UCP3, SLC25A9 uncoupling protein 3 (mitochondrial, proton carrier) C00004565
54658 UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) C00004565
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00004565
37618 C00004565
1437 CSF2, GMCSF colony stimulating factor 2 (granulocyte-macrophage) C00004565
1401 CRP, PTX1 C-reactive protein, pentraxin-related C00004565
54600 UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) C00004565
7402 UTRN, DMDL, DRP, DRP1 utrophin C00004565
8839 WISP2, CCN5, CT58, CTGF-L WNT1 inducible signaling pathway protein 2 C00004565
1244 ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP ATP-binding cassette, sub-family C (CFTR/MRP), member 2 C00001071
397 ARHGDIB, D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2 Rho GDP dissociation inhibitor (GDI) beta C00001071
847 CAT catalase (EC:1.11.1.6) C00001071
1312 COMT catechol-O-methyltransferase (EC:2.1.1.6) C00001071
1499 CTNNB1, CTNNB, MRD19, armadillo catenin (cadherin-associated protein), beta 1, 88kDa C00001071
1786 DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37) C00001071
54583 EGLN1, C1orf12, ECYT3, HIF-PH2, HIFPH2, HPH-2, HPH2, PHD2, SM20, ZMYND6 egl-9 family hypoxia-inducible factor 1 (EC:1.14.11.29) C00001071
1080 CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1 cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) C00004565
983 CDK1, CDC2, CDC28A, P34CDC2 cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) C00004565
6352 CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP chemokine (C-C motif) ligand 5 C00004565
4609 MYC, MRTL, MYCC, bHLHe39, c-Myc v-myc avian myelocytomatosis viral oncogene homolog C00001071
598 BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS BCL2-like 1 C00004565
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) C00001071
27113 BBC3, JFY-1, JFY1, PUMA BCL2 binding component 3 C00004565
23411 SIRT1, SIR2L1 sirtuin 1 C00001071
7153 TOP2A, TOP2, TP2A topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) C00001071
47 ACLY, ACL, ATPCL, CLATP ATP citrate lyase (EC:2.3.3.8) C00002724
358 AQP1, AQP-CHIP, CHIP28, CO aquaporin 1 C00002724
360 AQP3, AQP-3, GIL aquaporin 3 (Gill blood group) C00002724
367 AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM androgen receptor C00002724
960 CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1 CD44 molecule (Indian blood group) C00002724
999 CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO cadherin 1, type 1, E-cadherin (epithelial) C00002724
1277 COL1A1, OI4 collagen, type I, alpha 1 C00002724
4512 COX1, COI, MTCO1, MT-CO1 cytochrome c oxidase subunit I C00002724
114757 CYGB, HGB, STAP cytoglobin C00002724
1830 DSG3, CDHF6, PVA desmoglein 3 C00002724
1950 EGF, HOMG4, URG epidermal growth factor C00002724
2200 FBN1, ACMICD, ECTOL1, FBN, GPHYSD2, MASS, MFS1, OCTD, SGS, SSKS, WMS, WMS2 fibrillin 1 C00002724
2201 FBN2, CCA, DA9 fibrillin 2 C00002724
2246 FGF1, AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-1, FGF-alpha, FGFA, GLIO703, HBGF-1, HBGF1 fibroblast growth factor 1 (acidic) C00002724
2896 GRN, CLN11, GEP, GP88, PCDGF, PEPI, PGRN granulin C00002724
3036 HAS1, HAS hyaluronan synthase 1 (EC:2.4.1.212) C00002724
3315 HSPB1, CMT2F, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27 heat shock 27kDa protein 1 C00002724
3552 IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1 interleukin 1, alpha C00002724
3852 KRT5, CK5, DDD, DDD1, EBS2, K5, KRT5A keratin 5 C00002724
4157 MC1R, CMM5, MSH-R, SHEP2 melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) C00002724
4846 NOS3, ECNOS, eNOS nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) C00002724
8985 PLOD3, LH3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (EC:1.14.11.4) C00002724
5468 PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma peroxisome proliferator-activated receptor gamma C00002724
5886 RAD23A, HHR23A, HR23A RAD23 homolog A (S. cerevisiae) C00002724
5914 RARA, NR1B1, RAR retinoic acid receptor, alpha C00002724
6256 RXRA, NR2B1 retinoid X receptor, alpha C00002724
405 ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 aryl hydrocarbon receptor nuclear translocator C00004565
6716 SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (EC:1.3.1.22) C00002724
7178 TPT1, HRF, TCTP, p02, p23 tumor protein, translationally-controlled 1 C00002724
7295 TXN, TRDX, TRX, TRX1 thioredoxin C00002724
7299 TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 tyrosinase (EC:1.14.18.1) C00002724
7306 TYRP1, CAS2, CATB, GP75, OCA3, TRP, TRP1, TYRP, b-PROTEIN tyrosinase-related protein 1 (EC:1.14.18.-) C00002724
55 ACPP, 5'-NT, ACP-3, ACP3, PAP acid phosphatase, prostate (EC:3.1.3.2 3.1.3.5) C00011153
213 ALB, PRO0883, PRO0903, PRO1341 albumin C00011153
317 APAF1, APAF-1, CED4 apoptotic peptidase activating factor 1 C00011153
429 ASCL1, ASH1, HASH1, MASH1, bHLHa46 achaete-scute family bHLH transcription factor 1 C00011153
440 ASNS, TS11 asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4) C00011153
467 ATF3 activating transcription factor 3 C00011153
9474 ATG5, APG5, APG5-LIKE, APG5L, ASP, hAPG5 autophagy related 5 C00011153
654 BMP6, VGR, VGR1 bone morphogenetic protein 6 C00011153
2972 BRF1, BRF, BRF-1, GTF3B, TAF3B2, TAF3C, TAFIII90, TF3B90, TFIIIB90, hBRF BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit C00011153
811 CALR, CRT, RO, SSA, cC1qR calreticulin C00011153
6347 CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF chemokine (C-C motif) ligand 2 C00011153
929 CD14 CD14 molecule C00011153
1616 DAXX, BING2, DAP6, EAP1 death-domain associated protein C00011153
1676 DFFA, DFF-45, DFF1, ICAD DNA fragmentation factor, 45kDa, alpha polypeptide C00011153
1877 E4F1, E4F E4F transcription factor 1 C00011153
1960 EGR3, EGR-3, PILOT early growth response 3 C00011153
2033 EP300, KAT3B, RSTS2, p300 E1A binding protein p300 (EC:2.3.1.48) C00011153
2060 EPS15, AF-1P, AF1P, MLLT5 epidermal growth factor receptor pathway substrate 15 C00011153
2145 EZH1, KMT6B enhancer of zeste homolog 1 (Drosophila) (EC:2.1.1.43) C00011153
2161 F12, HAE3, HAEX, HAF coagulation factor XII (Hageman factor) (EC:3.4.21.38) C00011153
2260 FGFR1, BFGFR, CD331, CEK, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD, bFGF-R-1 fibroblast growth factor receptor 1 (EC:2.7.10.1) C00011153
2316 FLNA, ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD filamin A, alpha C00011153
2822 GPLD1, GPIPLD, GPIPLDM, PIGPLD, PIGPLD1 glycosylphosphatidylinositol specific phospholipase D1 (EC:3.1.4.50) C00011153
2941 GSTA4, GSTA4-4, GTA4 glutathione S-transferase alpha 4 (EC:2.5.1.18) C00011153
2961 GTF2E2, FE, TF2E2, TFIIE-B general transcription factor IIE, polypeptide 2, beta 34kDa C00011153
2968 GTF2H4, P52, TFB2, TFIIH general transcription factor IIH, polypeptide 4, 52kDa C00011153
9592 IER2, ETR101 immediate early response 2 C00011153
3485 IGFBP2, IBP2, IGF-BP53 insulin-like growth factor binding protein 2, 36kDa C00011153
3487 IGFBP4, BP-4, HT29-IGFBP, IBP4, IGFBP-4 insulin-like growth factor binding protein 4 C00011153
3554 IL1R1, CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80 interleukin 1 receptor, type I C00011153
239 ALOX12, 12-LOX, 12S-LOX, LOG12 arachidonate 12-lipoxygenase (EC:1.13.11.31) C00004565
3635 INPP5D, SHIP, SHIP-1, SHIP1, SIP-145, hp51CN inositol polyphosphate-5-phosphatase, 145kDa (EC:3.1.3.86) C00011153
10788 IQGAP2 IQ motif containing GTPase activating protein 2 C00011153
10379 IRF9, IRF-9, ISGF3, ISGF3G, p48 interferon regulatory factor 9 C00011153
354 KLK3, APS, KLK2A1, PSA, hK3 kallikrein-related peptidase 3 (EC:3.4.21.77) C00011153
9516 LITAF, PIG7, SIMPLE, TP53I7 lipopolysaccharide-induced TNF factor C00011153
4130 MAP1A, MAP1L, MTAP1A microtubule-associated protein 1A C00011153
23531 MMD, MMA, MMD1, PAQR11 monocyte to macrophage differentiation-associated C00011153
196 AHR, bHLHe76 aryl hydrocarbon receptor C00004565
4791 NFKB2, H2TF1, LYT-10, LYT10, NF-kB2, p105, p52 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) C00011153
4826 NNAT, Peg5 neuronatin C00011153
10528 NOP56, NOL5A, SCA36 NOP56 ribonucleoprotein C00011153
4862 NPAS2, MOP4, PASD4, bHLHe9 neuronal PAS domain protein 2 C00011153
5320 PLA2G2A, MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2 phospholipase A2, group IIA (platelets, synovial fluid) (EC:3.1.1.4) C00011153
5355 PLP2, A4, A4LSB proteolipid protein 2 (colonic epithelium-enriched) C00011153
5371 PML, MYL, PP8675, RNF71, TRIM19 promyelocytic leukemia C00011153
5467 PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB peroxisome proliferator-activated receptor delta C00011153
5592 PRKG1, 1, AAT8, PKG, PRKG1B, PRKGR1B, cGK, cGK_1, cGK1, cGKI, cGKI-BETA, cGKI-alpha protein kinase, cGMP-dependent, type I (EC:2.7.11.12) C00011153
5764 PTN, HARP, HBGF8, HBNF, NEGF1 pleiotrophin C00011153
5799 PTPRN2, IA-2beta, IAR, ICAAR, PTPRP, R-PTP-N2 protein tyrosine phosphatase, receptor type, N polypeptide 2 (EC:3.1.3.48) C00011153
5901 RAN, ARA24, Gsp1, TC4 RAN, member RAS oncogene family C00011153
8434 RECK, ST15 reversion-inducing-cysteine-rich protein with kazal motifs C00011153
8490 RGS5, MST092, MST106, MST129, MSTP032, MSTP092, MSTP106, MSTP129 regulator of G-protein signaling 5 C00011153
6319 SCD, FADS5, MSTP008, SCD1, SCDOS stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1) C00011153
4735 SEPT2, DIFF6, NEDD-5, NEDD5, Pnutl3, hNedd5 septin 2 C00011153
6774 STAT3, APRF, HIES signal transducer and activator of transcription 3 (acute-phase response factor) C00011153
9013 TAF1C, MGC:39976, SL1, TAFI110, TAFI95 TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa C00011153
6938 TCF12, CRS3, HEB, HTF4, HsT17266, bHLHb20 transcription factor 12 C00011153
7015 TERT, CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT telomerase reverse transcriptase (EC:2.7.7.49) C00011153
7040 TGFB1, CED, DPD1, LAP, TGFB, TGFbeta transforming growth factor, beta 1 C00011153
7360 UGP2, UDPG, UDPGP, UDPGP2, UGP1, UGPP1, UGPP2, pHC379 UDP-glucose pyrophosphorylase 2 (EC:2.7.7.9) C00011153
7375 USP4, UNP, Unph ubiquitin specific peptidase 4 (proto-oncogene) (EC:3.4.19.12) C00011153
7453 WARS, GAMMA-2, IFI53, IFP53 tryptophanyl-tRNA synthetase (EC:6.1.1.2) C00011153
7704 ZBTB16, PLZF, ZNF145 zinc finger and BTB domain containing 16 C00011153
7750 ZMYM2, FIM, MYM, RAMP, SCLL, ZNF198 zinc finger, MYM-type 2 C00011153
25 ABL1, ABL, JTK7, bcr/abl, c-ABL, p150, v-abl c-abl oncogene 1, non-receptor tyrosine kinase (EC:2.7.10.2) C00002647
338 APOB, FLDB, LDLCQ4 apolipoprotein B C00002647
545 ATR, FCTCS, FRP1, MEC1, SCKL, SCKL1 ataxia telangiectasia and Rad3 related (EC:2.7.11.1) C00002647
613 BCR, ALL, BCR1, CML, D22S11, D22S662, PHL breakpoint cluster region (EC:2.7.11.1) C00002647
4297 KMT2A, ALL-1, CXXC7, HRX, HTRX1, MLL, MLL/GAS7, MLL1A, TET1-MLL, TRX1, WDSTS lysine (K)-specific methyltransferase 2A (EC:2.1.1.43) C00004565
898 CCNE1, CCNE cyclin E1 C00002647
998 CDC42, CDC42Hs, G25K cell division cycle 42 C00002647
1027 CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 cyclin-dependent kinase inhibitor 1B (p27, Kip1) C00002647
7852 CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM chemokine (C-X-C motif) receptor 4 C00002647
356 FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 Fas ligand (TNF superfamily, member 6) C00002647
2551 GABPA, E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A, RCH04A07 GA binding protein transcription factor, alpha subunit 60kDa C00002647
2885 GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2 growth factor receptor-bound protein 2 C00002647
3551 IKBKB, IKK-beta, IKK2, IKKB, NFKBIKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) C00002647
3949 LDLR, FH, FHC, LDLCQ2 low density lipoprotein receptor C00002647
5604 MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1 mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) C00002647
5599 MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c mitogen-activated protein kinase 8 (EC:2.7.11.24) C00002647
5601 MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK mitogen-activated protein kinase 9 (EC:2.7.11.24) C00002647
4255 MGMT O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63) C00002647
4316 MMP7, MMP-7, MPSL1, PUMP-1 matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23) C00002647
4793 NFKBIB, IKBB, TRIP9 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta C00002647
5578 PRKCA, AAG6, PKC-alpha, PKCA, PRKACA protein kinase C, alpha (EC:2.7.11.13) C00002647
5591 PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350 protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1) C00002647
5879 RAC1, Rac-1, TC-25, p21-Rac1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) C00002647
19412 C00002647
387 RHOA, ARH12, ARHA, RHO12, RHOH12 ras homolog family member A C00002647
388 RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6 ras homolog family member B C00002647
6195 RPS6KA1, HU-1, MAPKAPK1A, RSK, RSK1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1) C00002647
9252 RPS6KA5, MSK1, MSPK1, RLPK ribosomal protein S6 kinase, 90kDa, polypeptide 5 (EC:2.7.11.1) C00002647
6622 SNCA, NACP, PARK1, PARK4, PD1 synuclein, alpha (non A4 component of amyloid precursor) C00002647
6817 SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) C00002647
7224 TRPC5, TRP5 transient receptor potential cation channel, subfamily C, member 5 C00002647
7422 VEGFA, MVCD1, VEGF, VPF vascular endothelial growth factor A C00002647
331 XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 X-linked inhibitor of apoptosis C00002647

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (174)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#613780 Aortic aneurysm, familial thoracic 7; aat7 Q15746
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
#600807 Asthma, susceptibility to Q13093
#208900 Ataxia-telangiectasia; at Q13315
#209950 Atypical mycobacteriosis, familial P42224
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#615007 Basal ganglia calcification, idiopathic, 4; ibgc4 P09619
#613985 Beta-thalassemia P68871
#603902 Beta-thalassemia, dominant inclusion body type P68871
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#614490 Blood group, junior system; jr Q9UNQ0
#210900 Bloom syndrome; blm P54132
%606641 Body mass index; bmi P37231
#114480 Breast cancer P31749
P42336
#614162 Candidiasis, familial, 7; candf7 P42224
#115150 Cardiofaciocutaneous syndrome 1; cfc1 P15056
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#609338 Carotid intimal medial thickness 1 P37231
#607271 Caspase 8 deficiency Q14790
#209880 Central hypoventilation syndrome, congenital; cchs P07949
#118300 Charcot-marie-tooth disease and deafness Q01453
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#118220 Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a Q01453
#613641 Charcot-marie-tooth disease, recessive intermediate b; cmtrib Q15046
#114500 Colorectal cancer; crc P07949
P15056
P18054
P31749
P42336
P84022
Q14191
#612918 Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi P42336
#615108 Cowden syndrome 5; cws5 P42336
#615109 Cowden syndrome 6; cws6 P31749
#218800 Crigler-najjar syndrome, type i P22309
#606785 Crigler-najjar syndrome, type ii P22309
#613916 Deafness, autosomal recessive 89; dfnb89 Q15046
#610549 Diabetes mellitus, insulin-resistant, with acanthosis nigricans P06213
#125853 Diabetes mellitus, noninsulin-dependent; niddm P06213
#119900 Digital clubbing, isolated congenital P15428
#246200 Donohue syndrome P06213
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#237500 Dubin-johnson syndrome; djs Q92887
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#133239 Esophageal cancer P04637
P18054
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#609446 Generalized epilepsy and paroxysmal dyskinesia; gepd Q12791
#143500 Gilbert syndrome P22309
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#137800 Glioma susceptibility 1; glm1 O75874
P04626
P37231
#232300 Glycogen storage disease ii P10253
#245590 Growth hormone insensitivity with immunodeficiency P51692
#139393 Guillain-barre syndrome, familial; gbs Q01453
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#140700 Heinz body anemias P68871
#602089 Hemangioma, capillary infantile P35916
P35968
#614519 Hemorrhage, intracerebral, susceptibility to; ich P12821
#114550 Hepatocellular carcinoma P08581
P42336
#142623 Hirschsprung disease, susceptibility to, 1; hscr1 P07949
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#147060 Hyper-ige recurrent infection syndrome, autosomal dominant P40763
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#143860 Hyperchlorhidrosis, isolated O43570
#609968 Hyperinsulinemic hypoglycemia, familial, 5; hhf5 P06213
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#145900 Hypertrophic neuropathy of dejerine-sottas Q01453
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#146300 Hypophosphatasia, adult P05186
#241510 Hypophosphatasia, childhood P05186
#241500 Hypophosphatasia, infantile P05186
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#147050 Ige responsiveness, atopic; iger Q13093
#612244 Inflammatory bowel disease 13; ibd13 P08183
#614328 Inflammatory skin and bowel disease, neonatal; nisbd P78536
#270450 Insulin-like growth factor i, resistance to P08069
#607785 Juvenile myelomonocytic leukemia; jmml P09619
#182000 Keratosis, seborrheic P42336
#613707 Leopard syndrome 3 P15056
#601626 Leukemia, acute myeloid; aml P09619
P36888
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
P04637
P15056
Q14790
#153100 Lymphedema, hereditary, ia P35916
#605027 Lymphoma, non-hodgkin, familial P15056
#300635 Lymphoproliferative syndrome, x-linked, 2; xlp2 P98170
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#602501 Megalencephaly-capillary malformation-polymicrogyria syndrome; mcap P42336
#603387 Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome; mpph P42336
#609048 Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 P11802
#614104 Mental retardation, autosomal dominant 7; mrd7 Q13627
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#612624 Microvascular complications of diabetes, susceptibility to, 3; mvcd3 P12821
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#171400 Multiple endocrine neoplasia, type iia; men2a P07949
#162300 Multiple endocrine neoplasia, type iib; men2b P07949
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#613796 Mycobacterial and viral infections, susceptibility to, autosomal recessive P42224
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#254500 Myeloma, multiple P24385
#131440 Myeloproliferative disorder, chronic, with eosinophilia P09619
#228550 Myofibromatosis, infantile, 1; imf1 P09619
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#613014 Neuroblastoma, susceptibility to, 3; nblst3 Q9UM73
#162500 Neuropathy, hereditary, with liability to pressure palsies; hnpp Q01453
#613706 Noonan syndrome 7; ns7 P15056
#601665 Obesity P37231
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
P42336
#260500 Papilloma of choroid plexus; cpp P04637
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#604229 Peters anomaly Q16678
#171300 Pheochromocytoma P07949
#172700 Pick disease of brain P10636
#262190 Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities P06213
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#614278 Platelet-activating factor acetylhydrolase deficiency; pafad Q13093
#176920 Proteus syndrome P31749
#191830 Renal adysplasia P07949
#605074 Renal cell carcinoma, papillary, 1; rccp1 P08581
#267430 Renal tubular dysgenesis; rtd P12821
#275210 Restrictive dermopathy, lethal P02545
#600852 Retinitis pigmentosa 17; rp17 P22748
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#609620 Short qt syndrome 1; sqt1 Q12809
#603903 Sickle cell anemia P68871
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
%612223 Stature quantitative trait locus 11; stqtl11 Q00534
#601367 Stroke, ischemic P12821
P16109
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#187950 Thrombocythemia 1; thcyt1 P40225
#155240 Thyroid carcinoma, familial medullary; mtc P07949
#188550 Thyroid carcinoma, papillary P07949
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#600195 Venous malformations, multiple cutaneous and mucosal; vmcm Q02763
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#277700 Werner syndrome; wrn Q14191
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253
#112100 Yt blood group antigen P22303

KEGG DISEASE (135)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
P04637 (marker)
P08581 (related)
Q16790 (marker)
H00016 Oral cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
P24385 (related)
P24385 (marker)
P40763 (related)
H00017 Esophageal cancer P00533 (related)
P04637 (related)
P04637 (marker)
P24385 (related)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
P04637 (related)
P08581 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
P04637 (related)
P68871 (marker)
H00028 Choriocarcinoma P00533 (related)
P04626 (related)
P04637 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
P11802 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
P09619 (related)
P11802 (related)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
P24385 (related)
P24385 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
Q01453 (related)
Q15046 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
P37231 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
P04637 (related)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
P11511 (related)
H00019 Pancreatic cancer P04626 (related)
P04637 (related)
P04637 (marker)
H00027 Ovarian cancer P04626 (related)
P04637 (related)
P42336 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
P04637 (related)
P24385 (related)
H00046 Cholangiocarcinoma P04626 (related)
P04637 (related)
P08581 (related)
P35354 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
Q01196 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
P28907 (marker)
Q13315 (related)
H00006 Hairy-cell leukemia P04637 (related)
P24385 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
P24385 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
Q9UM73 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
P08069 (related)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
P68871 (marker)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00029 Vulvar cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
P07949 (related)
P07949 (marker)
P15056 (related)
P27487 (marker)
P37231 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
P11802 (related)
P14679 (marker)
P15056 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00044 Cancer of the anal canal P04637 (related)
H00047 Gallbladder cancer P04637 (related)
P24385 (marker)
H00048 Hepatocellular carcinoma P04637 (related)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00213 Hypophosphatasia P05186 (related)
H00719 Leprechaunism P06213 (related)
H00942 Rabson-Mendenhall syndrome P06213 (related)
H01228 Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN) P06213 (related)
H01267 Familial hyperinsulinemic hypoglycemia (HHF) P06213 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00822 Renal agenesis and Renal adysplasia P07949 (related)
H00910 Hirschsprung disease (HD) P07949 (related)
H00916 Congenital central hypoventilation syndrome (CCHS) P07949 (related)
H00050 Synovial sarcoma P08069 (related)
H01274 Growth delay due to insulin-like growth factor I resistance P08069 (related)
H00024 Prostate cancer P09211 (related)
P09211 (marker)
P10275 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00023 Testicular cancer P10696 (marker)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00794 Aromatase excess syndrome P11511 (related)
H01205 Coumarin resistance P11712 (related)
H00083 Allograft rejection P12821 (related)
H00575 Renal tubular dysgenesis P12821 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00523 Noonan syndrome and related disorders P15056 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00208 Hyperbilirubinemia P22309 (related)
Q92887 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H00559 von Hippel-Lindau syndrome P24385 (related)
H00539 PTEN hamartoma tumor syndrome (PHTS) P31749 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00535 Lymphedemas P35916 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00409 Type II diabetes mellitus P37231 (related)
H00227 Congenital amegakaryocytic thrombocytopenia (CAMT) P40225 (marker)
H00107 Other well-defined immunodeficiency syndromes P40763 (related)
P98170 (related)
H00089 IFN-gamma/IL-12 axis P42224 (related)
H00363 Candidiasis P42224 (related)
H01109 Chronic mucocutaneous candidiasis (CMC) P42224 (related)
H00192 Xanthinuria P47989 (related)
H00931 Growth hormone insensitivity with immunodeficiency P51692 (related)
H00094 DNA repair defects P54132 (related)
Q13315 (related)
H00296 Defects in RecQ helicases P54132 (related)
Q14191 (related)
H00228 Thalassemia P68871 (related)
H00229 Sickle cell anemia (SCA) P68871 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00978 Thrombocytopenia (THC) Q01196 (related)
H01296 Hereditary neuropathy with liability to pressure palsies (HNPP) Q01453 (related)
H00531 Venous malformations Q02763 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H01258 Generalized epilepsy and paroxysmal dyskinesia (GEPD) Q12791 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00064 Ataxia telangiectasia (AT) Q13315 (related)
H00848 Ataxia with ocular apraxia (AOA) Q13315 (related)
H00108 Autoimmune lymphoproliferative syndromes (ALPS) Q14790 (related)
H00801 Familial thoracic aortic aneurysm and dissection (TAAD) Q15746 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

41 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D009203 Myocardial Infarction C00001071
C00011153
C00002647
D006937 Hypercholesterolemia C00002724
C00002647
D015228 Hypertriglyceridemia C00002724
C00002647
D006943 Hyperglycemia C00004565
C00002647
D015431 Weight Loss C00002724
D007938 Leukemia C00004565
D010024 Osteoporosis C00004565
D011297 Prenatal Exposure Delayed Effects C00004565
D010146 Pain C00005374
D013959 Thyroid Diseases C00002671
D005909 Glioblastoma C00001071
D002318 Cardiovascular Diseases C00004565
D000647 Amnesia C00002724
D056486 Drug-Induced Liver Injury C00002724
D009202 Cardiomyopathies C00004565
D006951 Hyperlipoproteinemias C00002724
D001943 Breast Neoplasms C00004565
D052456 Hypoalphalipoproteinemias C00002724
D008545 Melanoma C00002724
D009336 Necrosis C00002724
D050197 Atherosclerosis C00004565
D000014 Abnormalities, Drug-Induced C00011153
D002471 Cell Transformation, Neoplastic C00011153
D006965 Hyperplasia C00011153
D007248 Infertility, Male C00011153
D015427 Reperfusion Injury C00011153
D012878 Skin Neoplasms C00011153
D013471 Sunburn C00011153
D013733 Testicular Diseases C00011153
D003921 Diabetes Mellitus, Experimental C00002647
D050171 Dyslipidemias C00002647
D005234 Fatty Liver C00002647
D018149 Glucose Intolerance C00002647
D006949 Hyperlipidemias C00002647
D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive C00002647
D008546 Melanoma, Experimental C00002647
D009069 Movement Disorders C00002647
D009361 Neoplasm Invasiveness C00002647
D009362 Neoplasm Metastasis C00002647
D012516 Osteosarcoma C00002647
D010182 Pancreatic Diseases C00002647