KCF-S cluster No. 1590 (6 metabolites)

Corresponding Phytochemical cluster No. 82



Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00002644 External link 512 Catechol
/ Pyrocatechol
CHEMBL280998
C034221
148 / 82 / 64 22 / 5
C00002656 External link 512 Hydroquinone
/ 1,4-Benzenediol
CHEMBL537
C031927
55 / 48 / 51 156 / 14
C00002665 External link 512 Phloroglucinol
CHEMBL473159
D010696
3 / 4 / 2 8 / 2
C00002670 External link 512 Pyrogallol
CHEMBL307145
D011748
115 / 69 / 60 8 / 2
C00002671 External link 512 Resorcinol
CHEMBL24147
C031389
21 / 24 / 25 3 / 1
C00031480 External link 512 1,2,4-Trihydroxybenzene
C013038
66 / 2

Human Protein / Gene in interactions

170 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P00918 Carbonic anhydrase 2 Lyase C00002644 C00002656 C00002670 C00002671 1 / 2
P23280 Carbonic anhydrase 6 Lyase C00002644 C00002656 C00002670 C00002671 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00002644 C00002656 C00002670 C00002671 0 / 0
P02545 Prelamin-A/C Unclassified protein C00002644 C00002656 C00002670 C00002671 11 / 10
P10145 Interleukin-8 Secreted protein C00002644 C00002656 C00002670 C00002671 0 / 0
P00915 Carbonic anhydrase 1 Lyase C00002644 C00002656 C00002670 C00002671 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00002644 C00002656 C00002670 C00002671 3 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002644 C00002656 C00002670 C00002671 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002644 C00002656 C00002670 C00002671 0 / 1
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00002644 C00002656 C00002671 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00002644 C00002656 C00002670 0 / 0
P03372 Estrogen receptor NR3A1 C00002644 C00002656 C00002670 1 / 1
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00002644 C00002656 C00002671 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00002644 C00002656 C00002670 2 / 2
P10275 Androgen receptor NR3C4 C00002656 C00002670 C00002671 3 / 4
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00002644 C00002656 C00002670 0 / 3
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00002644 C00002656 C00002671 0 / 0
P43166 Carbonic anhydrase 7 Lyase C00002644 C00002656 C00002671 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00002644 C00002656 C00002671 0 / 1
P14679 Tyrosinase Oxidoreductase C00002665 C00002670 C00002671 4 / 2
P04150 Glucocorticoid receptor NR3C1 C00002644 C00002656 C00002670 0 / 1
P07451 Carbonic anhydrase 3 Lyase C00002644 C00002656 C00002671 0 / 0
P22748 Carbonic anhydrase 4 Lyase C00002644 C00002656 C00002671 1 / 1
O75496 Geminin Unclassified protein C00002644 C00002656 C00002671 0 / 0
O43570 Carbonic anhydrase 12 Lyase C00002644 C00002656 C00002671 1 / 2
Q9UBT6 DNA polymerase kappa Enzyme C00002644 C00002665 C00002670 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00002644 C00002656 C00002670 0 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase C00002644 C00002656 C00002671 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00002644 C00002656 C00002670 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00002644 C00002656 C00002670 0 / 0
P35372 Mu-type opioid receptor Opioid receptor C00002644 C00002670 0 / 0
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00002644 C00002670 1 / 1
P25021 Histamine H2 receptor Histamine receptor C00002644 C00002670 0 / 0
P35367 Histamine H1 receptor Histamine receptor C00002644 C00002670 0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine C00002644 C00002670 1 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor C00002644 C00002670 0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00002644 C00002670 0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor C00002644 C00002670 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00002644 C00002670 1 / 1
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor C00002644 C00002670 0 / 0
P06241 Tyrosine-protein kinase Fyn Src C00002644 C00002670 0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr C00002644 C00002670 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002644 C00002670 0 / 1
P42345 Serine/threonine-protein kinase mTOR Enzyme C00002644 C00002656 0 / 0
P54132 Bloom syndrome protein Enzyme C00002644 C00002656 1 / 2
P40225 Thrombopoietin Unclassified protein C00002644 C00002656 1 / 1
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00002644 C00002670 1 / 8
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002644 C00002656 0 / 0
P14416 D(2) dopamine receptor Dopamine receptor C00002644 C00002670 2 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00002644 C00002670 0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor C00002644 C00002670 0 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00002644 C00002670 0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor C00002644 C00002670 0 / 0
P29274 Adenosine receptor A2a Adenosine receptor C00002644 C00002670 0 / 0
Q99700 Ataxin-2 Unclassified protein C00002644 C00002656 1 / 1
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor C00002644 C00002670 0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor C00002644 C00002670 1 / 1
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor C00002644 C00002670 0 / 0
P17948 Vascular endothelial growth factor receptor 1 Vegfr C00002644 C00002670 0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor C00002644 C00002670 1 / 0
P06239 Tyrosine-protein kinase Lck Src C00002644 C00002670 0 / 1
P49798 Regulator of G-protein signaling 4 Unclassified protein C00002644 C00002656 2 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 C00002644 C00002670 1 / 1
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00002644 C00002670 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00002644 C00002656 0 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00002644 C00002670 0 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00002644 C00002656 0 / 0
P39748 Flap endonuclease 1 Enzyme C00002644 C00002656 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00002644 C00002670 2 / 2
P51151 Ras-related protein Rab-9A Unclassified protein C00002644 C00002656 0 / 0
P30542 Adenosine receptor A1 Adenosine receptor C00002644 C00002670 0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase C00002644 C00002670 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00002644 C00002670 0 / 0
P21917 D(4) dopamine receptor Dopamine receptor C00002644 C00002670 0 / 0
P30988 Calcitonin receptor Calcitonin receptor C00002644 C00002670 0 / 0
P35462 D(3) dopamine receptor Dopamine receptor C00002644 C00002670 1 / 0
P41143 Delta-type opioid receptor Opioid receptor C00002644 C00002670 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00002644 C00002670 0 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor C00002644 C00002670 0 / 0
P25101 Endothelin-1 receptor Endothelin receptor C00002644 C00002670 0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor C00002644 C00002670 0 / 0
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00002644 C00002670 0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor C00002644 C00002670 1 / 0
P27361 Mitogen-activated protein kinase 3 Erk C00002644 C00002670 0 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor C00002644 C00002670 0 / 0
P08311 Cathepsin G S1A C00002644 C00002670 0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00002644 C00002670 1 / 0
P03956 Interstitial collagenase M10A C00002644 C00002670 0 / 1
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor C00002644 C00002670 0 / 0
P23975 Sodium-dependent noradrenaline transporter Norepinephrine C00002644 C00002670 1 / 1
P21728 D(1A) dopamine receptor Dopamine receptor C00002644 C00002670 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00002644 C00002656 0 / 0
Q99549 M-phase phosphoprotein 8 Unclassified protein C00002644 C00002656 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00002644 C00002656 4 / 3
P17252 Protein kinase C alpha type Alpha C00002644 C00002670 0 / 0
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00002644 C00002670 2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00002644 C00002670 0 / 0
P29466 Caspase-1 C14 C00002644 C00002670 0 / 0
P21554 Cannabinoid receptor 1 Cannabinoid receptor C00002644 C00002670 0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin C00002644 C00002670 2 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00002644 C00002670 0 / 0
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00002644 C00002670 5 / 9
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00002644 C00002670 1 / 0
P21452 Substance-K receptor Neurokinin receptor C00002644 C00002670 0 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor C00002644 C00002670 0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor C00002644 C00002670 3 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor C00002644 C00002670 0 / 0
Q96RI1 Bile acid receptor NR1H4 C00002644 C00002656 0 / 0
P41597 C-C chemokine receptor type 2 CC chemokine receptor C00002644 C00002670 1 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00002644 C00002670 0 / 0
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme C00002644 C00002670 2 / 1
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 C00002644 C00002670 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002644 C00002670 0 / 0
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00002644 C00002670 2 / 2
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002644 C00002670 1 / 1
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor C00002644 C00002670 0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00002644 C00002656 0 / 0
O15118 Niemann-Pick C1 protein Unclassified protein C00002644 C00002656 1 / 1
Q01453 Peripheral myelin protein 22 Unclassified protein C00002644 C00002656 5 / 2
Q16539 Mitogen-activated protein kinase 14 p38 C00002644 C00002670 0 / 0
P08246 Neutrophil elastase S1A C00002644 C00002670 2 / 1
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A C00002644 C00002670 0 / 0
P33765 Adenosine receptor A3 Adenosine receptor C00002644 C00002670 0 / 0
P08588 Beta-1 adrenergic receptor Adrenergic receptor C00002644 C00002670 1 / 0
P22303 Acetylcholinesterase Hydrolase C00002644 C00002670 1 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00002644 C00002670 0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor C00002644 C00002670 0 / 0
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00002644 C00002670 0 / 1
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00002644 C00002670 0 / 0
P25103 Substance-P receptor Neurokinin receptor C00002644 C00002670 0 / 0
P25105 Platelet-activating factor receptor PAF receptor C00002644 C00002670 0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor C00002644 C00002670 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002644 C00002670 1 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00002656 0 / 0
P06746 DNA polymerase beta Enzyme C00002644 0 / 0
P16109 P-selectin Adhesion C00002670 1 / 0
P08253 72 kDa type IV collagenase M10A C00002644 1 / 3
P22894 Neutrophil collagenase M10A C00002644 0 / 0
P56817 Beta-secretase 1 A1A C00002665 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00002644 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00002644 0 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00002644 5 / 3
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00002670 5 / 1
P11021 78 kDa glucose-regulated protein Unclassified protein C00002644 0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00002644 0 / 0
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00002644 0 / 0
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00002644 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00002644 1 / 1
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00002656 0 / 0
P54855 UDP-glucuronosyltransferase 2B15 Enzyme C00002670 0 / 0
P68871 Hemoglobin subunit beta Secreted protein C00002656 4 / 4
P16581 E-selectin Adhesion C00002670 0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00002644 1 / 1
P10828 Thyroid hormone receptor beta NR1A2 C00002656 3 / 1
P35869 Aryl hydrocarbon receptor Transcription Factor C00002656 0 / 0
O15296 Arachidonate 15-lipoxygenase B Enzyme C00002644 0 / 0
P08254 Stromelysin-1 M10A C00002644 1 / 0
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00002656 0 / 0
Q9HAW8 UDP-glucuronosyltransferase 1-10 Enzyme C00002656 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00002670 2 / 3
Q16637 Survival motor neuron protein Unclassified protein C00002644 4 / 1
Q9HAW7 UDP-glucuronosyltransferase 1-7 Enzyme C00002656 0 / 0
Q9GZT9 Egl nine homolog 1 Enzyme C00002644 1 / 1
P02768 Serum albumin Secreted protein C00002670 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00002644 1 / 0
O00255 Menin Unclassified protein C00002656 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00002656 1 / 2
Q13951 Core-binding factor subunit beta Unclassified protein C00002670 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00002670 1 / 4
P14151 L-selectin Adhesion C00002670 0 / 0

214 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00002644 C00002656 C00002665 C00002670
6356 CCL11, SCYA11 chemokine (C-C motif) ligand 11 C00002644 C00002656 C00031480
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00002644 C00002656 C00031480
3043 HBB, CD113t-C, beta-globin hemoglobin, beta C00002644 C00002656 C00031480
7037 TFRC, CD71, T9, TFR, TFR1, TR, TRFR, p90 transferrin receptor C00002644 C00002656 C00031480
2623 GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT GATA binding protein 1 (globin transcription factor 1) C00002644 C00002656 C00031480
3586 IL10, CSIF, GVHDS, IL-10, IL10A, TGIF interleukin 10 C00002644 C00002656 C00031480
6347 CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF chemokine (C-C motif) ligand 2 C00002644 C00002656 C00031480
6348 CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 chemokine (C-C motif) ligand 3 C00002644 C00002656 C00031480
6351 CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4 chemokine (C-C motif) ligand 4 C00002644 C00002656 C00031480
6352 CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP chemokine (C-C motif) ligand 5 C00002644 C00002656 C00031480
1571 CYP2E1, CPE1, CYP2E, P450-J, P450C2E cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) C00002644 C00002656 C00031480
3145 HMBS, PBG-D, PBGD, PORC, UPS hydroxymethylbilane synthase (EC:2.5.1.61) C00002644 C00002656 C00031480
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00002656 C00031480
847 CAT catalase (EC:1.11.1.6) C00002656 C00002670
54205 CYCS, CYC, HCS, THC4 cytochrome c, somatic C00002656 C00002670
3337 DNAJB1, HSPF1, Hdj1, Hsp40, RSPH16B, Sis1 DnaJ (Hsp40) homolog, subfamily B, member 1 C00002656 C00031480
1436 CSF1R, C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R colony stimulating factor 1 receptor (EC:2.7.10.1) C00002656 C00031480
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00002656 C00002670
840 CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) C00002644 C00002656
9518 GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB growth differentiation factor 15 C00002656 C00002665
7296 TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR thioredoxin reductase 1 (EC:1.8.1.9) C00002656 C00031480
7153 TOP2A, TOP2, TP2A topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) C00002656 C00031480
4609 MYC, MRTL, MYCC, bHLHe39, c-Myc v-myc avian myelocytomatosis viral oncogene homolog C00002644 C00002656
2624 GATA2, DCML, MONOMAC, NFE1B GATA binding protein 2 C00002656 C00031480
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00002656 C00031480
1728 NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) C00002644 C00002656
4778 NFE2, NF-E2, p45 nuclear factor, erythroid 2 C00002656 C00031480
2993 GYPA, CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN, MNS, PAS-2 glycophorin A (MNS blood group) C00002656 C00031480
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) C00002656 C00002665
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00002656 C00002670
3569 IL6, BSF2, HGF, HSF, IFNB2, IL-6 interleukin 6 (interferon, beta 2) C00002656 C00031480
8337 HIST2H2AA3, H2A, H2A.2, H2A/O, H2A/q, H2AFO, H2a-615, HIST2H2AA histone cluster 2, H2aa3 C00002656 C00031480
1312 COMT catechol-O-methyltransferase (EC:2.1.1.6) C00002644 C00002670
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00002656 C00002665
8614 STC2, STC-2, STCRP stanniocalcin 2 C00002656
3320 HSP90AA1, EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2 heat shock protein 90kDa alpha (cytosolic), class A member 1 C00031480
3303 HSPA1A, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1 heat shock 70kDa protein 1A C00031480
3304 HSPA1B, HSP70-1B, HSP70-2 heat shock 70kDa protein 1B C00031480
3113 HLA-DPA1, DP(W3), DP(W4), HLA-DP1A, HLADP, HLASB, PLT1 major histocompatibility complex, class II, DP alpha 1 C00031480
8339 HIST1H2BG, H2B.1A, H2B/a, H2BFA, dJ221C16.8 histone cluster 1, H2bg C00031480
3280 HES1, HES-1, HHL, HRY, bHLHb39 hes family bHLH transcription factor 1 C00031480
3674 ITGA2B, BDPLT16, BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3 integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) C00031480
3690 ITGB3, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) C00031480
3720 JARID2, JMJ jumonji, AT rich interactive domain 2 C00031480
3750 KCND1, KV4.1 potassium voltage-gated channel, Shal-related subfamily, member 1 C00031480
9817 KEAP1, INrf2, KLHL19 kelch-like ECH-associated protein 1 C00031480
8440 NCK2, GRB4, NCKbeta NCK adaptor protein 2 C00031480
2812 GP1BB, BDPLT1, BS, CD42C, GPIBB glycoprotein Ib (platelet), beta polypeptide C00031480
22822 PHLDA1, DT1P1B11, PHRIP, TDAG51 pleckstrin homology-like domain, family A, member 1 C00031480
123 PLIN2, ADFP, ADRP perilipin 2 C00031480
4659 PPP1R12A, M130, MBS, MYPT1 protein phosphatase 1, regulatory subunit 12A C00031480
58497 PRUNE, DRES-17, DRES17, HTCD37 prune exopolyphosphatase (EC:3.6.1.1) C00031480
57403 RAB22A RAB22A, member RAS oncogene family C00031480
6138 RPL15, EC45, L15, RPL10, RPLY10, RPYL10 ribosomal protein L15 C00031480
6125 RPL5, DBA6, L5 ribosomal protein L5 C00031480
5176 SERPINF1, EPC-1, OI12, OI6, PEDF serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 C00031480
6452 SH3BP2, 3BP-2, 3BP2, CRBM, CRPM SH3-domain binding protein 2 C00031480
6653 SORL1, C11orf32, LR11, LRP9, SORLA, SorLA-1, gp250 sortilin-related receptor, L(DLR class) A repeats containing C00031480
8683 SRSF9, SFRS9, SRp30c serine/arginine-rich splicing factor 9 C00031480
2781 GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide C00031480
25907 TMEM158, BBP, RIS1, p40BBP transmembrane protein 158 (gene/pseudogene) C00031480
26088 GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 C00031480
126626 GABPB2 GA binding protein transcription factor, beta subunit 2 C00031480
9654 TTLL4 tubulin tyrosine ligase-like family, member 4 C00031480
2232 FDXR, ADXR ferredoxin reductase (EC:1.18.1.6) C00031480
2099 ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 estrogen receptor 1 C00002671
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00002671
7039 TGFA, TFGA transforming growth factor, alpha C00002671
64782 AEN, ISG20L1, pp12744 apoptosis enhancing nuclease C00002656
217 ALDH2, ALDH-E2, ALDHI, ALDM aldehyde dehydrogenase 2 family (mitochondrial) (EC:1.2.1.3) C00002656
396 ARHGDIA, GDIA1, NPHS8, RHOGDI, RHOGDI-1 Rho GDP dissociation inhibitor (GDI) alpha C00002656
468 ATF4, CREB-2, CREB2, TAXREB67, TXREB activating transcription factor 4 C00002656
572 BAD, BBC2, BCL2L8 BCL2-associated agonist of cell death C00002656
27113 BBC3, JFY-1, JFY1, PUMA BCL2 binding component 3 C00002656
330 BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 baculoviral IAP repeat containing 3 C00002656
664 BNIP3, NIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 C00002656
79866 BORA, C13orf34 bora, aurora kinase A activator C00002656
7832 BTG2, PC3, TIS21 BTG family, member 2 C00002656
55194 EVA1B, C1orf78, FAM176B, RP11-268J15.2 eva-1 homolog B (C. elegans) C00031480
839 CASP6, MCH2 caspase 6, apoptosis-related cysteine peptidase (EC:3.4.22.59) C00002656
30001 ERO1L, ERO1-alpha, ERO1A, ERO1LA ERO1-like (S. cerevisiae) C00031480
51386 EIF3L, EIF3EIP, EIF3S11, EIF3S6IP, HSPC021, HSPC025, MSTP005 eukaryotic translation initiation factor 3, subunit L C00031480
8661 EIF3A, EIF3, EIF3S10, P167, TIF32, eIF3-p170, eIF3-theta, p180, p185 eukaryotic translation initiation factor 3, subunit A C00031480
1593 CYP27A1, CP27, CTX, CYP27 cytochrome P450, family 27, subfamily A, polypeptide 1 (EC:1.14.13.15) C00031480
9134 CCNE2, CYCE2 cyclin E2 C00002656
899 CCNF, FBX1, FBXO1 cyclin F C00002656
942 CD86, B7-2, B7.2, B70, CD28LG2, LAB72 CD86 molecule C00002656
157313 CDCA2, Repo-Man cell division cycle associated 2 C00002656
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00002656
1058 CENPA, CENP-A, CenH3 centromere protein A C00002656
1277 COL1A1, OI4 collagen, type I, alpha 1 C00002656
1282 COL4A1, HANAC, ICH, POREN1, arresten collagen, type IV, alpha 1 C00002656
1437 CSF2, GMCSF colony stimulating factor 2 (granulocyte-macrophage) C00002656
6387 CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B chemokine (C-X-C motif) ligand 12 C00002656
2017 CTTN, EMS1 cortactin C00031480
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00002656
24300 C00002656
1565 CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) C00002656
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00002656
1577 CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3 cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1) C00002656
3491 CYR61, CCN1, GIG1, IGFBP10 cysteine-rich, angiogenic inducer, 61 C00002656
1611 DAP death-associated protein C00002656
1649 DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153 DNA-damage-inducible transcript 3 C00002656
54541 DDIT4, Dig2, REDD-1, REDD1 DNA-damage-inducible transcript 4 C00002656
22943 DKK1, DKK-1, SK dickkopf WNT signaling pathway inhibitor 1 C00002656
3301 DNAJA1, DJ-2, DjA1, HDJ2, HSDJ, HSJ2, HSPF4, NEDD7, hDJ-2 DnaJ (Hsp40) homolog, subfamily A, member 1 C00002656
1786 DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37) C00002656
1788 DNMT3A, DNMT3A2, M.HsaIIIA DNA (cytosine-5-)-methyltransferase 3 alpha (EC:2.1.1.37) C00002656
1789 DNMT3B, ICF, ICF1, M.HsaIIIB DNA (cytosine-5-)-methyltransferase 3 beta (EC:2.1.1.37) C00002656
1999 ELF3, EPR-1, ERT, ESE-1, ESX E74-like factor 3 (ets domain transcription factor, epithelial-specific ) C00002656
8772 FADD, MORT1 Fas (TNFRSF6)-associated via death domain C00002656
81610 FAM83D, C20orf129, CHICA, dJ616B8.3 family with sequence similarity 83, member D C00002656
26271 FBXO5, EMI1, FBX5, Fbxo31 F-box protein 5 C00002656
2335 FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF fibronectin 1 C00002656
2353 FOS, AP-1, C-FOS, p55 FBJ murine osteosarcoma viral oncogene homolog C00002656
2495 FTH1, FHC, FTH, FTHL6, PIG15, PLIF ferritin, heavy polypeptide 1 (EC:1.16.3.1) C00002656
1647 GADD45A, DDIT1, GADD45 growth arrest and DNA-damage-inducible, alpha C00002656
2730 GCLM, GLCLR glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2) C00002656
4363 ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 C00031480
2937 GSS, GSHS glutathione synthetase (EC:6.3.2.3) C00002656
2944 GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1 glutathione S-transferase mu 1 (EC:2.5.1.18) C00002656
3014 H2AFX, H2A.X, H2A/X, H2AX H2A histone family, member X C00002656
3009 HIST1H1B, H1, H1.5, H1B, H1F5, H1s-3 histone cluster 1, H1b C00002656
3007 HIST1H1D, H1.3, H1D, H1F3, H1s-2 histone cluster 1, H1d C00002656
3008 HIST1H1E, H1.4, H1E, H1F4, H1s-4, dJ221C16.5 histone cluster 1, H1e C00002656
85235 HIST1H2AH, H2A/S, H2AFALii, H2AH, dJ86C11.1 histone cluster 1, H2ah C00002656
8329 HIST1H2AI, H2A/c, H2AFC histone cluster 1, H2ai C00002656
8331 HIST1H2AJ, H2A/E, H2AFE, dJ160A22.4 histone cluster 1, H2aj C00002656
8358 HIST1H3B, H3/l, H3FL histone cluster 1, H3b C00002656
8352 HIST1H3C, H3.1, H3/c, H3FC histone cluster 1, H3c C00002656
8359 HIST1H4A, H4FA histone cluster 1, H4a C00002656
8366 HIST1H4B, H4/I, H4FI histone cluster 1, H4b C00002656
8364 HIST1H4C, H4/g, H4FG, dJ221C16.1 histone cluster 1, H4c C00002656
8367 HIST1H4E, H4/j, H4FJ histone cluster 1, H4e C00002656
8361 HIST1H4F, H4, H4/c, H4FC histone cluster 1, H4f C00002656
8365 HIST1H4H, H4/h, H4FH histone cluster 1, H4h C00002656
8362 HIST1H4K, H4/d, H4F2iii, H4FD, dJ160A22.1 histone cluster 1, H4k C00002656
317772 HIST2H2AB, H2AB histone cluster 2, H2ab C00002656
8338 HIST2H2AC, H2A, H2A-GL101, H2A/q, H2AFQ histone cluster 2, H2ac C00002656
8370 HIST2H4A, FO108, H4, H4/n, H4F2, H4FN, HIST2H4 histone cluster 2, H4a C00002656
55355 HJURP, FAKTS, URLC9, hFLEG1 Holliday junction recognition protein C00002656
3148 HMGB2, HMG2 high mobility group box 2 C00002656
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00002656
3306 HSPA2, HSP70-2, HSP70-3 heat shock 70kDa protein 2 C00002656
219844 HYLS1, HLS hydrolethalus syndrome 1 C00002656
3558 IL2, IL-2, TCGF, lymphokine interleukin 2 C00002656
3688 ITGB1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) C00002656
3689 ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) C00002656
182 JAG1, AGS, AHD, AWS, CD339, HJ1, JAGL1 jagged 1 C00002656
81930 KIF18A, MS-KIF18A kinesin family member 18A C00002656
4254 KITLG, FPH2, KL-1, Kitl, MGF, SCF, SF, SHEP7 KIT ligand C00002656
3910 LAMA4, CMD1JJ, LAMA3, LAMA4*-1 laminin, alpha 4 C00002656
11061 LECT1, BRICD3, CHM-I, CHM1, MYETS1 leukocyte cell derived chemotaxin 1 C00002656
4000 LMNA, CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, PRO1 lamin A/C C00002656
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00002656
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00002656
8932 MBD2, DMTase, NY-CO-41 methyl-CpG binding domain protein 2 C00002656
4257 MGST1, GST12, MGST, MGST-I microsomal glutathione S-transferase 1 (EC:2.5.1.18) C00002656
4323 MMP14, MMP-14, MMP-X1, MT-MMP, MT-MMP_1, MT1-MMP, MT1MMP, MTMMP1, WNCHRS matrix metallopeptidase 14 (membrane-inserted) (EC:3.4.24.80) C00002656
4324 MMP15, MT2-MMP, MTMMP2, SMCP-2 matrix metallopeptidase 15 (membrane-inserted) (EC:3.4.24.-) C00002656
4313 MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) C00002656
4314 MMP3, CHDS6, MMP-3, SL-1, STMY, STMY1, STR1 matrix metallopeptidase 3 (stromelysin 1, progelatinase) (EC:3.4.24.17) C00002656
4318 MMP9, CLG4B, GELB, MANDP2, MMP-9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) C00002656
4352 MPL, C-MPL, CD110, MPLV, THCYT2, TPOR myeloproliferative leukemia virus oncogene C00002656
4353 MPO myeloperoxidase (EC:1.11.2.2) C00002656
571 BACH1, BACH-1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 C00031480
4780 NFE2L2, NRF2 nuclear factor, erythroid 2-like 2 C00002656
10550 ARL6IP5, DERP11, GTRAP3-18, JWA, PRAF3, addicsin, hp22, jmx ADP-ribosylation-like factor 6 interacting protein 5 C00031480
5036 PA2G4, EBP1, HG4-1, p38-2G4 proliferation-associated 2G4, 38kDa C00002656
9870 AREL1, KIAA0317 apoptosis resistant E3 ubiquitin protein ligase 1 C00031480
25796 PGLS, 6PGL 6-phosphogluconolactonase (EC:3.1.1.31) C00002656
5429 POLH, RAD30, RAD30A, XP-V, XPV polymerase (DNA directed), eta (EC:2.7.7.7) C00002656
8493 PPM1D, PP2C-DELTA, WIP1 protein phosphatase, Mg2+/Mn2+ dependent, 1D (EC:3.1.3.16) C00002656
5052 PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2 peroxiredoxin 1 (EC:1.11.1.15) C00002656
5591 PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350 protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1) C00002656
84722 PSRC1, DDA3, FP3214 proline/serine-rich coiled-coil 1 C00002656
9401 RECQL4, RECQ4 RecQ protein-like 4 (EC:3.6.4.12) C00002656
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00002656
860 RUNX2, AML3, CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, PEA2aA, PEBP2aA runt-related transcription factor 2 C00002656
27244 SESN1, PA26, SEST1 sestrin 1 C00002656
83667 SESN2, HI95, SES2, SEST2 sestrin 2 C00002656
6647 SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer superoxide dismutase 1, soluble (EC:1.15.1.1) C00002656
6648 SOD2, IPOB, MNSOD, MVCD6 superoxide dismutase 2, mitochondrial (EC:1.15.1.1) C00002656
6688 SPI1, OF, PU.1, SFPI1, SPI-1, SPI-A spleen focus forming virus (SFFV) proviral integration oncogene C00002656
3115 HLA-DPB1, DPB1, HLA-DP, HLA-DP1B, HLA-DPB major histocompatibility complex, class II, DP beta 1 C00031480
7077 TIMP2, CSC-21K, DDC8 TIMP metallopeptidase inhibitor 2 C00002656
25976 TIPARP, ARTD14, PARP7, pART14 TCDD-inducible poly(ADP-ribose) polymerase (EC:2.4.2.30) C00002656
8795 TNFRSF10B, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9 tumor necrosis factor receptor superfamily, member 10b C00002656
8793 TNFRSF10D, CD264, DCR2, TRAIL-R4, TRAILR4, TRUNDD tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain C00002656
8718 TNFRSF25, APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR tumor necrosis factor receptor superfamily, member 25 C00002656
3604 TNFRSF9, 4-1BB, CD137, CDw137, ILA tumor necrosis factor receptor superfamily, member 9 C00002656
8742 TNFSF12, APO3L, DR3LG, TWEAK tumor necrosis factor (ligand) superfamily, member 12 C00002656
158 ADSL, AMPS, ASASE, ASL adenylosuccinate lyase (EC:4.3.2.2) C00031480
94241 TP53INP1, SIP, TP53DINP1, TP53INP1A, TP53INP1B, Teap, p53DINP1 tumor protein p53 inducible nuclear protein 1 C00002656
8717 TRADD, Hs.89862 TNFRSF1A-associated via death domain C00002656
9618 TRAF4, CART1, MLN62, RNF83 TNF receptor-associated factor 4 C00002656
286827 TRIM59, MRF1, RNF104, TRIM57, TSBF1 tripartite motif containing 59 C00002656
8989 TRPA1, ANKTM1, FEPS transient receptor potential cation channel, subfamily A, member 1 C00002656
7295 TXN, TRDX, TRX, TRX1 thioredoxin C00002656
7474 WNT5A, hWNT5A wingless-type MMTV integration site family, member 5A C00002656
7486 WRN, RECQ3, RECQL2, RECQL3 Werner syndrome, RecQ helicase-like (EC:3.6.4.12) C00002656
212 ALAS2, ALAS-E, ALASE, ANH1, ASB, XLDPP, XLEPP, XLSA aminolevulinate, delta-, synthase 2 (EC:2.3.1.37) C00002644
47 ACLY, ACL, ATPCL, CLATP ATP citrate lyase (EC:2.3.3.8) C00031480
6817 SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) C00002644
6799 SULT1A2, HAST4, P-PST, ST1A2, STP2, TSPST2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 (EC:2.8.2.1) C00002644
6818 SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1) C00002644
6819 SULT1C2, ST1C1, ST1C2, SULT1C1, humSULTC2 sulfotransferase family, cytosolic, 1C, member 2 (EC:2.8.2.-) C00002644
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00002665
581 BAX, BCL2L4 BCL2-associated X protein C00002665
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00002665
2932 GSK3B glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) C00002665
351 APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2 amyloid beta (A4) precursor protein C00002670
6622 SNCA, NACP, PARK1, PARK4, PD1 synuclein, alpha (non A4 component of amyloid precursor) C00002670

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (108)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#103780 Alcohol dependence P08172
P14416
P31645
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#613985 Beta-thalassemia P68871
#603902 Beta-thalassemia, dominant inclusion body type P68871
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#210900 Bloom syndrome; blm P54132
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
%606641 Body mass index; bmi P37231
#300615 Brunner syndrome P21397
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#609338 Carotid intimal medial thickness 1 P37231
#118300 Charcot-marie-tooth disease and deafness Q01453
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#118220 Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a Q01453
#614466 Coronary heart disease, susceptibility to, 6; chds6 P08254
#218800 Crigler-najjar syndrome, type i P22309
#606785 Crigler-najjar syndrome, type ii P22309
#162800 Cyclic neutropenia P08246
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#609820 Erythrocytosis, familial, 3; ecyt3 Q9GZT9
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#143500 Gilbert syndrome P22309
#137800 Glioma susceptibility 1; glm1 O75874
P04626
P37231
#139393 Guillain-barre syndrome, familial; gbs Q01453
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#140700 Heinz body anemias P68871
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#143860 Hyperchlorhidrosis, isolated O43570
#145000 Hyperparathyroidism 1; hrpt1 O00255
#145900 Hypertrophic neuropathy of dejerine-sottas Q01453
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#603932 Intervertebral disc disease; idd P14780
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
#608516 Major depressive disorder; mdd P08172
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#300705 Mental retardation, x-linked 17; mrx17 Q99714
%300852 Mental retardation, x-linked 88; mrx88 P50052
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#126200 Multiple sclerosis, susceptibility to; ms P08575
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#159900 Myoclonic dystonia P14416
#162500 Neuropathy, hereditary, with liability to pressure palsies; hnpp Q01453
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#257220 Niemann-pick disease, type c1; npc1 O15118
#601665 Obesity P32245
P37231
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
#260540 Parkinson-dementia syndrome P10636
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#607276 Resting heart rate, variation in P08588
#275210 Restrictive dermopathy, lethal P02545
#600852 Retinitis pigmentosa 17; rp17 P22748
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#603903 Sickle cell anemia P68871
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601367 Stroke, ischemic P16109
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#187950 Thrombocythemia 1; thcyt1 P40225
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#190300 Tremor, hereditary essential, 1; etm1 P35462
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#610379 West nile virus, susceptibility to P51681
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253
#112100 Yt blood group antigen P22303

KEGG DISEASE (88)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
P68871 (marker)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
P08253 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
Q01453 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
P37231 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
Q92731 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00019 Pancreatic cancer P04626 (related)
H00027 Ovarian cancer P04626 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
H00046 Cholangiocarcinoma P04626 (related)
P35354 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00079 Asthma P07550 (related)
H00100 Neutropenic disorders P08246 (related)
H00025 Penile cancer P08253 (related)
P14780 (related)
P35354 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00036 Osteosarcoma P08684 (marker)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00479 Metaphyseal dysplasias P14780 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00548 Brunner syndrome P21397 (related)
H00208 Hyperbilirubinemia P22309 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00227 Congenital amegakaryocytic thrombocytopenia (CAMT) P40225 (marker)
H00192 Xanthinuria P47989 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
Q99714 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
H00228 Thalassemia P68871 (related)
H00229 Sickle cell anemia (SCA) P68871 (related)
H00020 Colorectal cancer P68871 (marker)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H01296 Hereditary neuropathy with liability to pressure palsies (HNPP) Q01453 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00236 Congenital polycythemia Q9GZT9 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

17 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D048629 Micronuclei, Chromosome-Defective C00031480
C00002656
C00002644
C00002670
D011041 Poisoning C00031480
C00002656
C00002644
D009784 Occupational Diseases C00002656
C00002644
D013959 Thyroid Diseases C00002671
C00002665
D002869 Chromosome Aberrations C00002656
C00002644
D056486 Drug-Induced Liver Injury C00002656
C00002670
D007674 Kidney Diseases C00002656
D004487 Edema C00002656
D019457 Chromosome Breakage C00002656
D007680 Kidney Neoplasms C00002656
D008548 Melanosis C00002656
D001855 Bone Marrow Diseases C00002656
D011123 Polyploidy C00002656
D012140 Respiratory Tract Diseases C00002656
D012772 Shock, Septic C00002656
D012640 Seizures C00002644
D011832 Radiation Injuries C00002665