Punica granatum

• Index
• Plant Species
• Metabolite list (23)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Punica granatum
Genus	Punica
Family	Lythraceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Punica granatum
Linked NCBI taxonomy ID	22663
Linked level	species

Family

Family in NCBI taxonomy	Lythraceae
ID	3928

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (23)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00006728	Petunin / Petunidin 3,5-di-O-beta-D-glucoside					No. 1	No. 15
C00006709	Delphin / Delphinidin 3,5-diglucoside					No. 1	No. 15
C00013932	Quercetin 3,4'-dimethyl ether 7-alpha-L-Arabinofuranosyl-(1->6)-glucoside					No. 1	No. 15
C00006698	Myrtillin / Delphinidin 3-O-beta-D-glucopyranoside	CHEMBL518846				No. 2	No. 15
C00003741	Betulinic acid	CHEMBL269277 CHEMBL71690 CHEMBL519059 CHEMBL1318530 CHEMBL2005635	C002070	34 / 17 / 14	10 / 2	No. 23	No. 51
C00014337	5,7,3',4'-Tetrahydroxyflavanone 7-alpha-L-arabinofuranosyl-(1->6)-glucoside					No. 48	No. 14
C00014323	Isosakuranetin 7-alpha-L-arabinofuranosyl-(1->6)-glucoside / 5,7-Dihydroxy-4'-methoxyflavanone 7-alpha-L-arabinofuranosyl-(1->6)-glucoside					No. 48	No. 14
C00035378	Punicalagin	CHEMBL1984101	C115642			No. 142
C00037698	Punicacortein D	CHEMBL410634 CHEMBL505828				No. 142
C00036602	5-O-Galloylpunicacortein D					No. 142
C00031876	Icariside D1					No. 267
C00001236	Punicic acid					No. 367	No. 68
C00019308	Doursterol / Daucosterin / 3-O-beta-D-Glucopyranosyl sitosterol / beta-Sitosterol 3-O-beta-D-glucopyranoside	CHEMBL197711 CHEMBL506678 CHEMBL2304043	C011015	5 / 4 / 2	0 / 3	No. 520
C00002647	Gallic acid	CHEMBL288114	D005707	42 / 53 / 68	52 / 16	No. 817	No. 81
C00002915	Corilagin	CHEMBL449392 CHEMBL1425538	C049096	44 / 45 / 33		No. 818	No. 81
C00030754	Methyl gallate / Methyl 3,4,5-trihydroxybenzoate	CHEMBL65675	C052082	16 / 15 / 13		No. 1722
C00002678	Nasutin B / 3,3',4'-tri-O-methylellagic acid	CHEMBL451476				No. 2068	No. 81
C00011153	Gallogen / Ellagic acid / Elagostasine / Alizarin yellow	CHEMBL6246	D004610	104 / 97 / 100	77 / 9	No. 2068	No. 81
C00002062	(-)-Pelletierine					No. 3745	No. 1
C00036502	Arjuna / 2-O-Galloylpunicalin					No. 3879
C00037699	Punicalin		C115643			No. 3879
C00002300	Pseudopelletierine	CHEMBL1329064 CHEMBL2219893		8 / 3 / 5		No. 3916	No. 1
C00003663	Oestrone	CHEMBL756 CHEMBL32152 CHEMBL1405	D004970	132 / 76 / 56	51 / 14	No. 7711	No. 53

Human Protein / Gene in interactions

270 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P02545	Prelamin-A/C	Unclassified protein	C00002647 C00002915 C00003663 C00003741 C00011153 C00030754	11 / 10
P06746	DNA polymerase beta	Enzyme	C00002915 C00003741 C00011153 C00019308 C00030754	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00002647 C00002915 C00011153 C00030754	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002300 C00003663 C00003741 C00011153	1 / 1
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002300 C00003663 C00003741 C00011153	0 / 1
P28482	Mitogen-activated protein kinase 1	Erk	C00002300 C00002647 C00003663 C00011153	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00002647 C00002915 C00003663 C00011153	4 / 3
P83916	Chromobox protein homolog 1	Unclassified protein	C00002300 C00003663 C00011153 C00030754	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002647 C00002915 C00011153 C00030754	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002647 C00002915 C00003663	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002647 C00011153 C00030754	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00002647 C00003741 C00011153	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00002915 C00003741 C00011153	2 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00003741 C00011153 C00019308	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002647 C00011153 C00030754	1 / 1
P00918	Carbonic anhydrase 2	Lyase	C00002647 C00003663 C00011153	1 / 2
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00002915 C00011153 C00030754	0 / 0
P15121	Aldose reductase	Enzyme	C00002647 C00003741 C00011153	0 / 0
O75496	Geminin	Unclassified protein	C00003663 C00003741 C00011153	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00002647 C00002915 C00011153	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00002915 C00011153 C00030754	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00002915 C00003663 C00011153	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00002915 C00011153 C00030754	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002300 C00003663 C00003741	0 / 1
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00002915 C00011153 C00030754	1 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002300 C00003663 C00003741	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002300 C00003663 C00003741	1 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00002915 C00003741 C00011153	0 / 0
P54132	Bloom syndrome protein	Enzyme	C00002915 C00003663 C00011153	1 / 2
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002647 C00003663 C00011153	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002647 C00002915 C00011153	2 / 2
P04406	Glyceraldehyde-3-phosphate dehydrogenase	Enzyme	C00002647 C00002915 C00011153	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00002915 C00011153 C00030754	0 / 0
P12821	Angiotensin-converting enzyme	M2	C00002647 C00002915 C00011153	4 / 2
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00003663 C00003741	0 / 0
P03372	Estrogen receptor	NR3A1	C00002647 C00003663	1 / 1
P05771	Protein kinase C beta type	Alpha	C00002915 C00003741	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00002915 C00003663	0 / 0
P43166	Carbonic anhydrase 7	Lyase	C00002647 C00011153	0 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00002647 C00011153	0 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00002647 C00011153	0 / 1
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00002647 C00011153	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00002647 C00003663	5 / 1
P08581	Hepatocyte growth factor receptor	TK tyrosine-protein kinase MET subfamily	C00002647 C00011153	2 / 3
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00003663 C00011153	5 / 9
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00002647 C00003663	0 / 3
P04150	Glucocorticoid receptor	NR3C1	C00002647 C00003663	0 / 1
P07451	Carbonic anhydrase 3	Lyase	C00002647 C00011153	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002915 C00011153	1 / 2
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00002915 C00030754	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00003741 C00011153	1 / 1
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00003663 C00003741	0 / 0
P22748	Carbonic anhydrase 4	Lyase	C00002647 C00011153	1 / 1
P00915	Carbonic anhydrase 1	Lyase	C00002647 C00011153	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00003741 C00011153	1 / 0
Q02156	Protein kinase C epsilon type	Eta	C00002915 C00003741	0 / 0
Q07820	Induced myeloid leukemia cell differentiation protein Mcl-1	Other cytosolic protein	C00002915 C00011153	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00002915 C00011153	2 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00002647 C00011153	7 / 37
Q13951	Core-binding factor subunit beta	Unclassified protein	C00002915 C00011153	0 / 1
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00003663 C00003741	0 / 0
O43570	Carbonic anhydrase 12	Lyase	C00002647 C00011153	1 / 2
Q9ULX7	Carbonic anhydrase 14	Lyase	C00002647 C00011153	0 / 0
Q01196	Runt-related transcription factor 1	Unclassified protein	C00002915 C00011153	1 / 4
P23280	Carbonic anhydrase 6	Lyase	C00002647 C00011153	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00002647 C00011153	2 / 3
P11387	DNA topoisomerase 1	Isomerase	C00002915 C00003741	0 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00003663 C00011153	1 / 8
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00002647 C00011153	0 / 0
P08107	Heat shock 70 kDa protein 1A/1B	Unclassified protein	C00011153	0 / 0
P24385	G1/S-specific cyclin-D1	Other cytosolic protein	C00011153	1 / 8
Q9HC97	G-protein coupled receptor 35	Kynurenic acid receptor	C00011153	0 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00011153	1 / 0
Q9HAW7	UDP-glucuronosyltransferase 1-7	Enzyme	C00003663	0 / 0
P11802	Cyclin-dependent kinase 4	CMGC serine/threonine protein kinase family	C00011153	1 / 3
P16662	UDP-glucuronosyltransferase 2B7	Enzyme	C00003663	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00003741	0 / 0
O00444	Serine/threonine-protein kinase PLK4	PLK serine/threonine protein kinase subfamily	C00011153	0 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00003663	2 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00003663	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00003663	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00003663	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00003663	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00003663	0 / 0
Q06520	Bile salt sulfotransferase	Enzyme	C00003663	0 / 0
P15559	NAD(P)H dehydrogenase [quinone] 1	Enzyme	C00003741	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00003663	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00003663	1 / 1
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00011153	0 / 0
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00003663	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00003663	1 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00003663	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00002647	0 / 0
P16581	E-selectin	Adhesion	C00002647	0 / 0
P68871	Hemoglobin subunit beta	Secreted protein	C00011153	4 / 4
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00002915	2 / 2
P06241	Tyrosine-protein kinase Fyn	Src	C00003663	0 / 0
P04278	Sex hormone-binding globulin	Secreted protein	C00003663	0 / 0
P36888	Receptor-type tyrosine-protein kinase FLT3	Pdgfr	C00011153	1 / 1
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00003663	0 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00003663	0 / 0
P54760	Ephrin type-B receptor 4	Eph	C00011153	0 / 0
P78536	Disintegrin and metalloproteinase domain-containing protein 17	M12B	C00002647	1 / 0
P08183	Multidrug resistance protein 1	drug	C00003663	1 / 0
P08151	Zinc finger protein GLI1	Unclassified protein	C00003741	0 / 0
P08842	Steryl-sulfatase	Enzyme	C00003663	1 / 1
P51452	Dual specificity protein phosphatase 3	Ser_Thr_Tyr	C00011153	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00003663	0 / 0
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00003663	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00003663	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00003663	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00003663	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00003663	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00003663	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00003663	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00003663	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00003663	0 / 0
P02768	Serum albumin	Secreted protein	C00030754	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00003663	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00003663	0 / 0
P10145	Interleukin-8	Secreted protein	C00002647	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00003663	1 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00003663	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00003663	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00003663	0 / 0
P08311	Cathepsin G	S1A	C00003663	0 / 0
Q05397	Focal adhesion kinase 1	Fak	C00011153	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00003663	1 / 0
P09211	Glutathione S-transferase P	Enzyme	C00011153	0 / 1
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00003663	0 / 0
Q02763	Angiopoietin-1 receptor	Tie	C00011153	1 / 1
P03956	Interstitial collagenase	M10A	C00003663	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00003663	0 / 0
P15056	Serine/threonine-protein kinase B-raf	Raf	C00011153	6 / 3
Q04206	Transcription factor p65	Transcription Factor	C00003741	0 / 0
P07237	Protein disulfide-isomerase	Enzyme	C00003663	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00003663	1 / 0
O60285	NUAK family SNF1-like kinase 1	CAMK serine/threonine protein kinase NUAK subfamily	C00011153	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00003663	0 / 0
P11308	Transcriptional regulator ERG	Unclassified protein	C00002300	1 / 2
P25021	Histamine H2 receptor	Histamine receptor	C00003663	0 / 0
Q4U2R8	Solute carrier family 22 member 6	Antiporter	C00011153	0 / 0
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00003663	1 / 1
P98073	Enteropeptidase	Enzyme	C00002915	1 / 1
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00003741	0 / 0
O75897	Sulfotransferase 1C4	Enzyme	C00003663	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00011153	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00011153	0 / 0
P00734	Prothrombin	S1A	C00019308	4 / 2
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00003663	0 / 1
P06213	Insulin receptor	TK tyrosine-protein kinase INSR subfamily	C00011153	5 / 4
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00003663	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00003663	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00003663	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00003663	2 / 0
P68400	Casein kinase II subunit alpha	Ck2	C00011153	0 / 0
P09619	Platelet-derived growth factor receptor beta	Pdgfr	C00011153	5 / 1
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00003663	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00003663	0 / 0
P12931	Proto-oncogene tyrosine-protein kinase Src	Src	C00011153	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00003663	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00003663	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00003663	0 / 0
Q96GD4	Aurora kinase B	Aur	C00011153	0 / 0
P35968	Vascular endothelial growth factor receptor 2	Vegfr	C00011153	1 / 0
Q96RI1	Bile acid receptor	NR1H4	C00003741	0 / 0
Q13133	Oxysterols receptor LXR-alpha	NR1H3	C00003741	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00011153	3 / 1
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00003663	1 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00030754	1 / 1
P35916	Vascular endothelial growth factor receptor 3	Vegfr	C00011153	2 / 1
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00003663	2 / 1
P08047	Transcription factor Sp1	Unclassified protein	C00019308	0 / 0
P00390	Glutathione reductase, mitochondrial	Oxidoreductase	C00011153	0 / 0
P55789	FAD-linked sulfhydryl oxidase ALR	Enzyme	C00030754	1 / 0
P55055	Oxysterols receptor LXR-beta	NR1H3	C00003741	0 / 0
P41279	Mitogen-activated protein kinase kinase kinase 8	Ste11	C00011153	0 / 0
Q8TDU6	G-protein coupled bile acid receptor 1	Steroid-like ligand receptor	C00003741	0 / 0
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00003663	2 / 0
Q13315	Serine-protein kinase ATM	Atypical serine/threonine protein kinase PIKK subfamily	C00011153	1 / 4
Q01453	Peripheral myelin protein 22	Unclassified protein	C00003663	5 / 2
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00003663	0 / 0
Q9BR01	Sulfotransferase 4A1	Enzyme	C00003663	0 / 0
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00003663	0 / 0
Q9Y4X1	UDP-glucuronosyltransferase 2A1	Enzyme	C00003663	0 / 0
P06133	UDP-glucuronosyltransferase 2B4	Enzyme	C00003663	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00003663	0 / 0
O14965	Aurora kinase A	Aur	C00011153	0 / 0
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00003663	1 / 0
Q8N1Q1	Carbonic anhydrase 13	Lyase	C00011153	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00003663	1 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00003663	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00003663	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00003663	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00003663	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00003663	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00003663	0 / 0
P08185	Corticosteroid-binding globulin	Secreted protein	C00003663	1 / 1
P53350	Serine/threonine-protein kinase PLK1	PLK serine/threonine protein kinase subfamily	C00011153	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00003663	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00003663	2 / 2
P27361	Mitogen-activated protein kinase 3	Erk	C00003663	0 / 0
Q02880	DNA topoisomerase 2-beta	Isomerase	C00011153	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00011153	0 / 0
P31749	RAC-alpha serine/threonine-protein kinase	Akt	C00011153	4 / 1
P14151	L-selectin	Adhesion	C00002647	0 / 0
P16109	P-selectin	Adhesion	C00002647	1 / 0
P29466	Caspase-1	C14	C00003663	0 / 0
P37059	Estradiol 17-beta-dehydrogenase 2	Enzyme	C00003663	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00003663	0 / 0
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00003663	0 / 0
P07949	Proto-oncogene tyrosine-protein kinase receptor Ret	Ret	C00011153	9 / 4
Q16539	Mitogen-activated protein kinase 14	p38	C00003663	0 / 0
Q13093	Platelet-activating factor acetylhydrolase	Enzyme	C00002647	3 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00003663	0 / 0
P08246	Neutrophil elastase	S1A	C00003663	2 / 1
P08069	Insulin-like growth factor 1 receptor	TK tyrosine-protein kinase INSR subfamily	C00011153	1 / 3
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00003663	0 / 0
Q53GQ0	Estradiol 17-beta-dehydrogenase 12	Enzyme	C00003663	0 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00003663	2 / 2
P10275	Androgen receptor	NR3C4	C00003663	3 / 4
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00003663	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00003663	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00003663	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00003663	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00003663	1 / 1
P21728	D(1A) dopamine receptor	Dopamine receptor	C00003663	0 / 0
P06239	Tyrosine-protein kinase Lck	Src	C00003663	0 / 1
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00003663	0 / 0
Q13627	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	CMGC dual-specificity kinase DYRK1	C00011153	1 / 0
P49888	Estrogen sulfotransferase	Enzyme	C00003663	0 / 0
O60218	Aldo-keto reductase family 1 member B10	Enzyme	C00003741	0 / 0
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00003663	0 / 0
P11142	Heat shock cognate 71 kDa protein	Unclassified protein	C00011153	0 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00003663	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00011153	0 / 0
P56937	3-keto-steroid reductase	Enzyme	C00003663	0 / 0
Q9Y6L6	Solute carrier organic anion transporter family member 1B1	Electrochemical transporter	C00003663	1 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00002647	4 / 1
P55072	Transitional endoplasmic reticulum ATPase	Unclassified protein	C00002915	2 / 1
O75795	UDP-glucuronosyltransferase 2B17	Enzyme	C00003663	1 / 0
Q8IUX4	DNA dC->dU-editing enzyme APOBEC-3F	Enzyme	C00003741	0 / 0
O00255	Menin	Unclassified protein	C00011153	2 / 5
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00019308	0 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00003663	3 / 0
Q05513	Protein kinase C zeta type	Iota	C00002915	0 / 0
Q04759	Protein kinase C theta type	Delta	C00002915	0 / 1
O94806	Serine/threonine-protein kinase D3	Pkd	C00002915	0 / 0
Q05655	Protein kinase C delta type	Delta	C00002915	0 / 0
P05129	Protein kinase C gamma type	Alpha	C00002915	1 / 1
P24723	Protein kinase C eta type	Eta	C00002915	1 / 0
P41743	Protein kinase C iota type	Iota	C00002915	0 / 0
Q15139	Serine/threonine-protein kinase D1	Pkd	C00002915	0 / 0
Q9NSA0	Solute carrier family 22 member 11	Transporter	C00011153	0 / 0
P20248	Cyclin-A2	Other cytosolic protein	C00011153	0 / 0
P78396	Cyclin-A1	Other cytosolic protein	C00011153	0 / 0
P24941	Cyclin-dependent kinase 2	Cdc2	C00011153	0 / 0
P22694	cAMP-dependent protein kinase catalytic subunit beta	Pka	C00011153	0 / 0
P17612	cAMP-dependent protein kinase catalytic subunit alpha	Pka	C00011153	0 / 0
P22612	cAMP-dependent protein kinase catalytic subunit gamma	Pka	C00011153	0 / 0
Q9UBT2	SUMO-activating enzyme subunit 2	Enzyme	C00003741	0 / 0
Q9UBE0	SUMO-activating enzyme subunit 1	Unclassified protein	C00003741	0 / 0
P19429	Troponin I, cardiac muscle	Unclassified protein	C00002915	4 / 4
P45379	Troponin T, cardiac muscle	Unclassified protein	C00002915	3 / 5
P63316	Troponin C, slow skeletal and cardiac muscles	Other cytosolic protein	C00002915	2 / 2
Q9UM73	ALK tyrosine kinase receptor	TKL serine/threonine protein kinase STKR type 1 subfamily	C00011153	1 / 1
P06748	Nucleophosmin	Other nuclear protein	C00011153	0 / 0
P14061	Estradiol 17-beta-dehydrogenase 1	Enzyme	C00003663	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00002915	2 / 1
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00003663	1 / 1

169 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00002647 C00003663 C00003741 C00011153
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00002647 C00003663 C00003741
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00002647 C00003663 C00003741
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00002647 C00003663 C00003741
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00002647 C00003663
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00002647 C00003663
331	XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3	X-linked inhibitor of apoptosis	C00002647 C00003663
581	BAX, BCL2L4	BCL2-associated X protein	C00002647 C00003741
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00003663 C00003741
7453	WARS, GAMMA-2, IFI53, IFP53	tryptophanyl-tRNA synthetase (EC:6.1.1.2)	C00003663 C00011153
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00002647 C00011153
4313	MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24)	C00002647 C00011153
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00002647 C00011153
1960	EGR3, EGR-3, PILOT	early growth response 3	C00003663 C00011153
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00003663 C00011153
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00002647 C00011153
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00003663
467	ATF3	activating transcription factor 3	C00011153
654	BMP6, VGR, VGR1	bone morphogenetic protein 6	C00011153
2972	BRF1, BRF, BRF-1, GTF3B, TAF3B2, TAF3C, TAFIII90, TF3B90, TFIIIB90, hBRF	BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit	C00011153
811	CALR, CRT, RO, SSA, cC1qR	calreticulin	C00011153
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00011153
929	CD14	CD14 molecule	C00011153
440	ASNS, TS11	asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4)	C00011153
1616	DAXX, BING2, DAP6, EAP1	death-domain associated protein	C00011153
1676	DFFA, DFF-45, DFF1, ICAD	DNA fragmentation factor, 45kDa, alpha polypeptide	C00011153
1877	E4F1, E4F	E4F transcription factor 1	C00011153
429	ASCL1, ASH1, HASH1, MASH1, bHLHa46	achaete-scute family bHLH transcription factor 1	C00011153
2033	EP300, KAT3B, RSTS2, p300	E1A binding protein p300 (EC:2.3.1.48)	C00011153
2060	EPS15, AF-1P, AF1P, MLLT5	epidermal growth factor receptor pathway substrate 15	C00011153
2145	EZH1, KMT6B	enhancer of zeste homolog 1 (Drosophila) (EC:2.1.1.43)	C00011153
2161	F12, HAE3, HAEX, HAF	coagulation factor XII (Hageman factor) (EC:3.4.21.38)	C00011153
2260	FGFR1, BFGFR, CD331, CEK, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD, bFGF-R-1	fibroblast growth factor receptor 1 (EC:2.7.10.1)	C00011153
2316	FLNA, ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD	filamin A, alpha	C00011153
2822	GPLD1, GPIPLD, GPIPLDM, PIGPLD, PIGPLD1	glycosylphosphatidylinositol specific phospholipase D1 (EC:3.1.4.50)	C00011153
2941	GSTA4, GSTA4-4, GTA4	glutathione S-transferase alpha 4 (EC:2.5.1.18)	C00011153
2961	GTF2E2, FE, TF2E2, TFIIE-B	general transcription factor IIE, polypeptide 2, beta 34kDa	C00011153
2968	GTF2H4, P52, TFB2, TFIIH	general transcription factor IIH, polypeptide 4, 52kDa	C00011153
3091	HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	C00011153
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00011153
9592	IER2, ETR101	immediate early response 2	C00011153
3485	IGFBP2, IBP2, IGF-BP53	insulin-like growth factor binding protein 2, 36kDa	C00011153
3487	IGFBP4, BP-4, HT29-IGFBP, IBP4, IGFBP-4	insulin-like growth factor binding protein 4	C00011153
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00011153
3554	IL1R1, CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80	interleukin 1 receptor, type I	C00011153
317	APAF1, APAF-1, CED4	apoptotic peptidase activating factor 1	C00011153
3635	INPP5D, SHIP, SHIP-1, SHIP1, SIP-145, hp51CN	inositol polyphosphate-5-phosphatase, 145kDa (EC:3.1.3.86)	C00011153
10788	IQGAP2	IQ motif containing GTPase activating protein 2	C00011153
10379	IRF9, IRF-9, ISGF3, ISGF3G, p48	interferon regulatory factor 9	C00011153
354	KLK3, APS, KLK2A1, PSA, hK3	kallikrein-related peptidase 3 (EC:3.4.21.77)	C00011153
9516	LITAF, PIG7, SIMPLE, TP53I7	lipopolysaccharide-induced TNF factor	C00011153
4130	MAP1A, MAP1L, MTAP1A	microtubule-associated protein 1A	C00011153
23531	MMD, MMA, MMD1, PAQR11	monocyte to macrophage differentiation-associated	C00011153
213	ALB, PRO0883, PRO0903, PRO1341	albumin	C00011153
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00011153
4791	NFKB2, H2TF1, LYT-10, LYT10, NF-kB2, p105, p52	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	C00011153
4826	NNAT, Peg5	neuronatin	C00011153
10528	NOP56, NOL5A, SCA36	NOP56 ribonucleoprotein	C00011153
4862	NPAS2, MOP4, PASD4, bHLHe9	neuronal PAS domain protein 2	C00011153
9970	NR1I3, CAR, CAR1, MB67	nuclear receptor subfamily 1, group I, member 3	C00011153
8505	PARG, PARG99	poly (ADP-ribose) glycohydrolase (EC:3.2.1.143)	C00011153
5320	PLA2G2A, MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2	phospholipase A2, group IIA (platelets, synovial fluid) (EC:3.1.1.4)	C00011153
5355	PLP2, A4, A4LSB	proteolipid protein 2 (colonic epithelium-enriched)	C00011153
5371	PML, MYL, PP8675, RNF71, TRIM19	promyelocytic leukemia	C00011153
5467	PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB	peroxisome proliferator-activated receptor delta	C00011153
5592	PRKG1, 1, AAT8, PKG, PRKG1B, PRKGR1B, cGK, cGK_1, cGK1, cGKI, cGKI-BETA, cGKI-alpha	protein kinase, cGMP-dependent, type I (EC:2.7.11.12)	C00011153
5764	PTN, HARP, HBGF8, HBNF, NEGF1	pleiotrophin	C00011153
5799	PTPRN2, IA-2beta, IAR, ICAAR, PTPRP, R-PTP-N2	protein tyrosine phosphatase, receptor type, N polypeptide 2 (EC:3.1.3.48)	C00011153
5901	RAN, ARA24, Gsp1, TC4	RAN, member RAS oncogene family	C00011153
8434	RECK, ST15	reversion-inducing-cysteine-rich protein with kazal motifs	C00011153
55	ACPP, 5'-NT, ACP-3, ACP3, PAP	acid phosphatase, prostate (EC:3.1.3.2 3.1.3.5)	C00011153
8490	RGS5, MST092, MST106, MST129, MSTP032, MSTP092, MSTP106, MSTP129	regulator of G-protein signaling 5	C00011153
6319	SCD, FADS5, MSTP008, SCD1, SCDOS	stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1)	C00011153
4735	SEPT2, DIFF6, NEDD-5, NEDD5, Pnutl3, hNedd5	septin 2	C00011153
6649	SOD3, EC-SOD	superoxide dismutase 3, extracellular (EC:1.15.1.1)	C00011153
6774	STAT3, APRF, HIES	signal transducer and activator of transcription 3 (acute-phase response factor)	C00011153
9013	TAF1C, MGC:39976, SL1, TAFI110, TAFI95	TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa	C00011153
6938	TCF12, CRS3, HEB, HTF4, HsT17266, bHLHb20	transcription factor 12	C00011153
7015	TERT, CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT	telomerase reverse transcriptase (EC:2.7.7.49)	C00011153
7019	TFAM, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3	transcription factor A, mitochondrial	C00011153
7040	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta	transforming growth factor, beta 1	C00011153
7360	UGP2, UDPG, UDPGP, UDPGP2, UGP1, UGPP1, UGPP2, pHC379	UDP-glucose pyrophosphorylase 2 (EC:2.7.7.9)	C00011153
7375	USP4, UNP, Unph	ubiquitin specific peptidase 4 (proto-oncogene) (EC:3.4.19.12)	C00011153
7153	TOP2A, TOP2, TP2A	topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3)	C00003741
7704	ZBTB16, PLZF, ZNF145	zinc finger and BTB domain containing 16	C00011153
7750	ZMYM2, FIM, MYM, RAMP, SCLL, ZNF198	zinc finger, MYM-type 2	C00011153
7150	TOP1, TOPI	topoisomerase (DNA) I (EC:5.99.1.2)	C00003741
9429	ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1	ATP-binding cassette, sub-family G (WHITE), member 2	C00003663
8644	AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS	aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357)	C00003663
250	ALPP, ALP, PALP, PLAP, PLAP-1	alkaline phosphatase, placental (EC:3.1.3.1)	C00003663
367	AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM	androgen receptor	C00003663
396	ARHGDIA, GDIA1, NPHS8, RHOGDI, RHOGDI-1	Rho GDP dissociation inhibitor (GDI) alpha	C00003663
1312	COMT	catechol-O-methyltransferase (EC:2.1.1.6)	C00003663
1586	CYP17A1, CPT7, CYP17, P450C17, S17AH	cytochrome P450, family 17, subfamily A, polypeptide 1 (EC:1.14.99.9 4.1.2.30)	C00003663
1588	CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM	cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00003663
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00003663
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00003663
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00003663
1551	CYP3A7, CP37, CYPIIIA7, P450-HFLA	cytochrome P450, family 3, subfamily A, polypeptide 7 (EC:1.14.14.1)	C00003663
2026	ENO2, NSE	enolase 2 (gamma, neuronal) (EC:4.2.1.11)	C00003663
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00003663
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00003663
3292	HSD17B1, EDH17B2, EDHB17, HSD17, SDR28C1	hydroxysteroid (17-beta) dehydrogenase 1 (EC:1.1.1.62)	C00003663
51144	HSD17B12, KAR, SDR12C1	hydroxysteroid (17-beta) dehydrogenase 12 (EC:1.1.1.62)	C00003663
3294	HSD17B2, EDH17B2, HSD17, SDR9C2	hydroxysteroid (17-beta) dehydrogenase 2 (EC:1.1.1.62 1.1.1.239)	C00003663
3295	HSD17B4, DBP, MFE-2, MPF-2, PRLTS1, SDR8C1	hydroxysteroid (17-beta) dehydrogenase 4 (EC:4.2.1.107 4.2.1.119 1.1.1.n12)	C00003663
51478	HSD17B7, PRAP, SDR37C1	hydroxysteroid (17-beta) dehydrogenase 7 (EC:1.1.1.62 1.1.1.270)	C00003663
8202	NCOA3, ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP	nuclear receptor coactivator 3 (EC:2.3.1.48)	C00003663
5154	PDGFA, PDGF-A, PDGF1	platelet-derived growth factor alpha polypeptide	C00003663
5174	PDZK1, CAP70, CLAMP, NHERF-3, NHERF3, PDZD1	PDZ domain containing 1	C00003663
5241	PGR, NR3C3, PR	progesterone receptor	C00003663
6286	S100P, MIG9	S100 calcium binding protein P	C00003663
8991	SELENBP1, LPSB, SBP56, SP56, hSBP	selenium binding protein 1	C00003663
6558	SLC12A2, BSC, BSC2, NKCC1	solute carrier family 12 (sodium/potassium/chloride transporter), member 2	C00003663
23657	SLC7A11, CCBR1, xCT	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11	C00003663
412	STS, ARSC, ARSC1, ASC, ES, SSDD, XLI	steroid sulfatase (microsomal), isozyme S (EC:3.1.6.2)	C00003663
6818	SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1)	C00003663
6783	SULT1E1, EST, EST-1, ST1E1, STE	sulfotransferase family 1E, estrogen-preferring, member 1 (EC:2.8.2.4)	C00003663
25830	SULT4A1, BR-STL-1, BRSTL1, DJ388M5.3, NST, SULTX3, hBR-STL-1	sulfotransferase family 4A, member 1 (EC:2.8.2.-)	C00003663
7031	TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2	trefoil factor 1	C00003663
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00003741
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00003663
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00003663
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00003663
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00003663
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00003663
9474	ATG5, APG5, APG5-LIKE, APG5L, ASP, hAPG5	autophagy related 5	C00011153
7364	UGT2B7, UDPGT_2B9, UDPGT2B7, UDPGTH2, UGT2B9	UDP glucuronosyltransferase 2 family, polypeptide B7 (EC:2.4.1.17)	C00003663
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00003741
25	ABL1, ABL, JTK7, bcr/abl, c-ABL, p150, v-abl	c-abl oncogene 1, non-receptor tyrosine kinase (EC:2.7.10.2)	C00002647
338	APOB, FLDB, LDLCQ4	apolipoprotein B	C00002647
472	ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1	ataxia telangiectasia mutated (EC:2.7.11.1)	C00002647
545	ATR, FCTCS, FRP1, MEC1, SCKL, SCKL1	ataxia telangiectasia and Rad3 related (EC:2.7.11.1)	C00002647
613	BCR, ALL, BCR1, CML, D22S11, D22S662, PHL	breakpoint cluster region (EC:2.7.11.1)	C00002647
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00002647
898	CCNE1, CCNE	cyclin E1	C00002647
998	CDC42, CDC42Hs, G25K	cell division cycle 42	C00002647
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00002647
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00002647
1147	CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16	conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10)	C00002647
7852	CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM	chemokine (C-X-C motif) receptor 4	C00002647
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00002647
356	FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6	Fas ligand (TNF superfamily, member 6)	C00002647
2551	GABPA, E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A, RCH04A07	GA binding protein transcription factor, alpha subunit 60kDa	C00002647
2885	GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2	growth factor receptor-bound protein 2	C00002647
3551	IKBKB, IKK-beta, IKK2, IKKB, NFKBIKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)	C00002647
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00002647
3949	LDLR, FH, FHC, LDLCQ2	low density lipoprotein receptor	C00002647
5604	MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1	mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)	C00002647
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00002647
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00002647
4255	MGMT	O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63)	C00002647
4316	MMP7, MMP-7, MPSL1, PUMP-1	matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23)	C00002647
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00002647
4793	NFKBIB, IKBB, TRIP9	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	C00002647
5578	PRKCA, AAG6, PKC-alpha, PKCA, PRKACA	protein kinase C, alpha (EC:2.7.11.13)	C00002647
5591	PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350	protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1)	C00002647
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00002647
5879	RAC1, Rac-1, TC-25, p21-Rac1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	C00002647
19412			C00002647
387	RHOA, ARH12, ARHA, RHO12, RHOH12	ras homolog family member A	C00002647
388	RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6	ras homolog family member B	C00002647
6195	RPS6KA1, HU-1, MAPKAPK1A, RSK, RSK1	ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1)	C00002647
9252	RPS6KA5, MSK1, MSPK1, RLPK	ribosomal protein S6 kinase, 90kDa, polypeptide 5 (EC:2.7.11.1)	C00002647
6622	SNCA, NACP, PARK1, PARK4, PD1	synuclein, alpha (non A4 component of amyloid precursor)	C00002647
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00002647
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00002647
7224	TRPC5, TRP5	transient receptor potential cation channel, subfamily C, member 5	C00002647
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00002647

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