| class name | count |
|---|---|
| rosids | 15 |
| Liliopsida | 2 |
| eudicotyledons | 2 |
| Magnoliophyta | 1 |
| class name | count |
|---|---|
| Anacardiaceae | 3 |
| Aceraceae | 2 |
| Combretaceae | 2 |
| Euphorbiaceae | 2 |
| Geraniaceae | 2 |
| Crassulaceae | 1 |
| Paeoniaceae | 1 |
| Nymphaeaceae | 1 |
| Dictyotaceae | 1 |
| Lythraceae | 1 |
| Betulaceae | 1 |
| Begoniaceae | 1 |
| Iridaceae | 1 |
| Meliaceae | 1 |
| Hypoxidaceae | 1 |
| Rhodomelaceae | 1 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00030222
|
Progallin A
/ Ethyl gallate |
CHEMBL453196
|
C048734
|
|
||
|
C00030754
|
Methyl gallate
/ Methyl 3,4,5-trihydroxybenzoate |
CHEMBL65675
|
C052082
|
16 / 15 / 13 |
|
|
|
C00031089
|
Protocatechuic acid methyl ester
|
CHEMBL486027
|
7 / 3 / 5 |
|
||
|
C00032950
|
Ethyl protocatechuate
/ Ethyl 3,4-dihydroxybenzoate |
CHEMBL486216
|
C018063
|
7 / 3 / 5 |
|
|
|
C00044447
|
3-Bromo-4,5-dihydroxybenzoic acid methyl ester
|
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00031089 C00032950 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00031089 C00032950 | 0 / 1 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00031089 C00032950 | 0 / 0 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00031089 C00032950 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00031089 C00032950 | 1 / 2 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00031089 C00032950 | 1 / 2 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00030754 C00031089 | 1 / 1 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00030754 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00030754 | 11 / 10 |
| P02768 | Serum albumin | Secreted protein | C00030754 | 0 / 0 |
| Q9GZT9 | Egl nine homolog 1 | Enzyme | C00032950 | 1 / 1 |
| P55789 | FAD-linked sulfhydryl oxidase ALR | Enzyme | C00030754 | 1 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00030754 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00030754 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00030754 | 1 / 1 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00030754 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00030754 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00030754 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00030754 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00030754 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00030754 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00030754 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00030754 | 1 / 1 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #609820 | Erythrocytosis, familial, 3; ecyt3 |
Q9GZT9
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #613076 | Myopathy, mitochondrial progressive, with congenital cataract, hearing loss, and developmental delay |
P55789
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #278300 | Xanthinuria, type i |
P47989
|
| KEGG | name | UniProt |
|---|---|---|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
Q16790 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00236 | Congenital polycythemia |
Q9GZT9
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|