Organism name | Geranium thunbergii |
---|---|
Genus | Geranium |
Family | Geraniaceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Geranium thunbergii |
---|---|
Linked NCBI taxonomy ID | 345239 |
Linked level | species |
Family in NCBI taxonomy | Geraniaceae |
---|---|
ID | 4027 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | rosids |
---|---|
ID | 71275 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00035368
![]() |
Phyllanthusiin D
|
No. 226 | No. 81 |
![]() |
||||
C00035322
![]() |
Geraniinic acid C
|
No. 226 | No. 81 |
![]() |
||||
C00035321
![]() |
Geraniinic acid B
|
No. 226 | No. 81 |
![]() |
||||
C00002647
![]() |
Gallic acid
|
CHEMBL288114
|
D005707
|
42 / 53 / 68 | 52 / 16 | No. 817 | No. 81 |
![]() |
C00002915
![]() |
Corilagin
|
CHEMBL449392
CHEMBL1425538 |
C049096
|
44 / 45 / 33 | No. 818 | No. 81 |
![]() |
|
C00002670
![]() |
Pyrogallol
|
CHEMBL307145
|
D011748
|
115 / 69 / 60 | 8 / 2 | No. 1590 | No. 82 |
![]() |
C00011153
![]() |
Gallogen
/ Ellagic acid / Elagostasine / Alizarin yellow |
CHEMBL6246
|
D004610
|
104 / 97 / 100 | 77 / 9 | No. 2068 | No. 81 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00002647 C00002670 C00002915 C00011153 | 0 / 0 |
P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00002647 C00002670 C00002915 C00011153 | 0 / 0 |
P02545 | Prelamin-A/C | Unclassified protein | C00002647 C00002670 C00002915 C00011153 | 11 / 10 |
P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002647 C00002670 C00002915 C00011153 | 2 / 2 |
Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00002647 C00002670 C00011153 | 3 / 3 |
P00915 | Carbonic anhydrase 1 | Lyase | C00002647 C00002670 C00011153 | 0 / 0 |
Q13951 | Core-binding factor subunit beta | Unclassified protein | C00002670 C00002915 C00011153 | 0 / 1 |
P28482 | Mitogen-activated protein kinase 1 | Erk | C00002647 C00002670 C00011153 | 0 / 0 |
Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00002647 C00002670 C00011153 | 1 / 1 |
P23280 | Carbonic anhydrase 6 | Lyase | C00002647 C00002670 C00011153 | 0 / 0 |
Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00002647 C00002915 C00011153 | 0 / 0 |
Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00002670 C00002915 C00011153 | 1 / 4 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00002647 C00002670 C00011153 | 0 / 0 |
P12821 | Angiotensin-converting enzyme | M2 | C00002647 C00002915 C00011153 | 4 / 2 |
P00918 | Carbonic anhydrase 2 | Lyase | C00002647 C00002670 C00011153 | 1 / 2 |
P11473 | Vitamin D3 receptor | NR1I1 | C00002647 C00002670 C00011153 | 2 / 3 |
O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00002647 C00002670 C00011153 | 0 / 0 |
P04406 | Glyceraldehyde-3-phosphate dehydrogenase | Enzyme | C00002647 C00002915 C00011153 | 0 / 0 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00002647 C00002915 C00011153 | 4 / 3 |
Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00002647 C00002670 C00002915 | 0 / 0 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00002915 C00011153 | 1 / 2 |
P17252 | Protein kinase C alpha type | Alpha | C00002670 C00002915 | 0 / 0 |
P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00002647 C00011153 | 0 / 0 |
Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00002647 C00011153 | 0 / 0 |
P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00002647 C00002670 | 5 / 1 |
Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00002915 C00011153 | 0 / 0 |
P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00002915 C00011153 | 1 / 1 |
O75164 | Lysine-specific demethylase 4A | Enzyme | C00002915 C00011153 | 0 / 0 |
Q9UNA4 | DNA polymerase iota | Enzyme | C00002915 C00011153 | 0 / 0 |
O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00002915 C00011153 | 0 / 0 |
P07451 | Carbonic anhydrase 3 | Lyase | C00002647 C00011153 | 0 / 0 |
P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00002670 C00011153 | 1 / 1 |
P16109 | P-selectin | Adhesion | C00002647 C00002670 | 1 / 0 |
P06746 | DNA polymerase beta | Enzyme | C00002915 C00011153 | 0 / 0 |
P14151 | L-selectin | Adhesion | C00002647 C00002670 | 0 / 0 |
P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00002670 C00011153 | 0 / 0 |
P22748 | Carbonic anhydrase 4 | Lyase | C00002647 C00011153 | 1 / 1 |
P03372 | Estrogen receptor | NR3A1 | C00002647 C00002670 | 1 / 1 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002647 C00011153 | 0 / 0 |
P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00002670 C00011153 | 0 / 0 |
Q16790 | Carbonic anhydrase 9 | Lyase | C00002647 C00011153 | 0 / 1 |
P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00002647 C00002670 | 0 / 3 |
P08581 | Hepatocyte growth factor receptor | TK tyrosine-protein kinase MET subfamily | C00002647 C00011153 | 2 / 3 |
P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00002670 C00011153 | 5 / 9 |
P04150 | Glucocorticoid receptor | NR3C1 | C00002647 C00002670 | 0 / 1 |
P43166 | Carbonic anhydrase 7 | Lyase | C00002647 C00011153 | 0 / 0 |
P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00002915 C00011153 | 2 / 0 |
P10145 | Interleukin-8 | Secreted protein | C00002647 C00002670 | 0 / 0 |
P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00002670 C00011153 | 0 / 1 |
P15121 | Aldose reductase | Enzyme | C00002647 C00011153 | 0 / 0 |
P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00002915 C00011153 | 2 / 0 |
Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00002915 C00011153 | 0 / 0 |
P54132 | Bloom syndrome protein | Enzyme | C00002915 C00011153 | 1 / 2 |
P39748 | Flap endonuclease 1 | Enzyme | C00002915 C00011153 | 0 / 0 |
O43570 | Carbonic anhydrase 12 | Lyase | C00002647 C00011153 | 1 / 2 |
P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00002670 C00011153 | 1 / 8 |
P16581 | E-selectin | Adhesion | C00002647 C00002670 | 0 / 0 |
Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Other cytosolic protein | C00002915 C00011153 | 0 / 0 |
P00352 | Retinal dehydrogenase 1 | Enzyme | C00002647 C00002670 | 0 / 0 |
Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00002647 C00011153 | 0 / 0 |
P04637 | Cellular tumor antigen p53 | Transcription Factor | C00002647 C00011153 | 7 / 37 |
O60285 | NUAK family SNF1-like kinase 1 | CAMK serine/threonine protein kinase NUAK subfamily | C00011153 | 0 / 0 |
Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00002670 | 0 / 0 |
P29274 | Adenosine receptor A2a | Adenosine receptor | C00002670 | 0 / 0 |
P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00002670 | 0 / 0 |
P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00002670 | 0 / 0 |
P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00002670 | 1 / 1 |
O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00011153 | 0 / 0 |
P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00002670 | 0 / 0 |
P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00002670 | 1 / 0 |
P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00002670 | 0 / 0 |
P14416 | D(2) dopamine receptor | Dopamine receptor | C00002670 | 2 / 0 |
P11387 | DNA topoisomerase 1 | Isomerase | C00002915 | 0 / 0 |
P68871 | Hemoglobin subunit beta | Secreted protein | C00011153 | 4 / 4 |
P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00002915 | 2 / 2 |
Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00011153 | 1 / 0 |
P36888 | Receptor-type tyrosine-protein kinase FLT3 | Pdgfr | C00011153 | 1 / 1 |
P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00002670 | 0 / 0 |
P54760 | Ephrin type-B receptor 4 | Eph | C00011153 | 0 / 0 |
Q9HC97 | G-protein coupled receptor 35 | Kynurenic acid receptor | C00011153 | 0 / 0 |
P24385 | G1/S-specific cyclin-D1 | Other cytosolic protein | C00011153 | 1 / 8 |
P11802 | Cyclin-dependent kinase 4 | CMGC serine/threonine protein kinase family | C00011153 | 1 / 3 |
O75496 | Geminin | Unclassified protein | C00011153 | 0 / 0 |
P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00002670 | 0 / 0 |
P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00002670 | 0 / 0 |
P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00002670 | 0 / 0 |
P21917 | D(4) dopamine receptor | Dopamine receptor | C00002670 | 0 / 0 |
P30988 | Calcitonin receptor | Calcitonin receptor | C00002670 | 0 / 0 |
P35462 | D(3) dopamine receptor | Dopamine receptor | C00002670 | 1 / 0 |
P41143 | Delta-type opioid receptor | Opioid receptor | C00002670 | 0 / 0 |
Q92731 | Estrogen receptor beta | NR3A2 | C00002670 | 0 / 1 |
P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00002670 | 0 / 0 |
O00444 | Serine/threonine-protein kinase PLK4 | PLK serine/threonine protein kinase subfamily | C00011153 | 0 / 0 |
P25101 | Endothelin-1 receptor | Endothelin receptor | C00002670 | 0 / 0 |
P30411 | B2 bradykinin receptor | Bradykinin receptor | C00002670 | 0 / 0 |
Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00002670 | 0 / 0 |
P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00002670 | 1 / 0 |
P06241 | Tyrosine-protein kinase Fyn | Src | C00002670 | 0 / 0 |
P49841 | Glycogen synthase kinase-3 beta | Gsk | C00011153 | 0 / 0 |
P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00002670 | 0 / 0 |
P08311 | Cathepsin G | S1A | C00002670 | 0 / 0 |
Q05397 | Focal adhesion kinase 1 | Fak | C00011153 | 0 / 0 |
Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00002670 | 1 / 0 |
P09211 | Glutathione S-transferase P | Enzyme | C00011153 | 0 / 1 |
Q02763 | Angiopoietin-1 receptor | Tie | C00011153 | 1 / 1 |
P03956 | Interstitial collagenase | M10A | C00002670 | 0 / 1 |
P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00002670 | 0 / 0 |
P15056 | Serine/threonine-protein kinase B-raf | Raf | C00011153 | 6 / 3 |
P08107 | Heat shock 70 kDa protein 1A/1B | Unclassified protein | C00011153 | 0 / 0 |
Q9Y253 | DNA polymerase eta | Enzyme | C00011153 | 1 / 1 |
P41145 | Kappa-type opioid receptor | Opioid receptor | C00002670 | 0 / 0 |
Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00002915 | 0 / 0 |
P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00002670 | 0 / 0 |
Q4U2R8 | Solute carrier family 22 member 6 | Antiporter | C00011153 | 0 / 0 |
P83916 | Chromobox protein homolog 1 | Unclassified protein | C00011153 | 0 / 0 |
P98073 | Enteropeptidase | Enzyme | C00002915 | 1 / 1 |
P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00011153 | 0 / 0 |
O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00011153 | 0 / 0 |
P78536 | Disintegrin and metalloproteinase domain-containing protein 17 | M12B | C00002647 | 1 / 0 |
P06213 | Insulin receptor | TK tyrosine-protein kinase INSR subfamily | C00011153 | 5 / 4 |
P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00002670 | 2 / 0 |
P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00002670 | 0 / 0 |
P14679 | Tyrosinase | Oxidoreductase | C00002670 | 4 / 2 |
P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00002670 | 0 / 0 |
P31645 | Sodium-dependent serotonin transporter | Serotonin | C00002670 | 2 / 0 |
P51452 | Dual specificity protein phosphatase 3 | Ser_Thr_Tyr | C00011153 | 0 / 0 |
P09619 | Platelet-derived growth factor receptor beta | Pdgfr | C00011153 | 5 / 1 |
P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00002670 | 1 / 0 |
P21452 | Substance-K receptor | Neurokinin receptor | C00002670 | 0 / 0 |
P12931 | Proto-oncogene tyrosine-protein kinase Src | Src | C00011153 | 0 / 0 |
P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00002670 | 0 / 0 |
P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00002670 | 3 / 0 |
P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00002670 | 0 / 0 |
Q96GD4 | Aurora kinase B | Aur | C00011153 | 0 / 0 |
P35968 | Vascular endothelial growth factor receptor 2 | Vegfr | C00011153 | 1 / 0 |
P02768 | Serum albumin | Secreted protein | C00002670 | 0 / 0 |
P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00002670 | 1 / 0 |
P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00002670 | 0 / 0 |
P35916 | Vascular endothelial growth factor receptor 3 | Vegfr | C00011153 | 2 / 1 |
P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00002670 | 2 / 1 |
P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00002670 | 0 / 0 |
P00390 | Glutathione reductase, mitochondrial | Oxidoreductase | C00011153 | 0 / 0 |
P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00002670 | 0 / 0 |
P41279 | Mitogen-activated protein kinase kinase kinase 8 | Ste11 | C00011153 | 0 / 0 |
P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00002670 | 0 / 0 |
Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00002670 | 1 / 0 |
O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00002670 | 0 / 0 |
P35367 | Histamine H1 receptor | Histamine receptor | C00002670 | 0 / 0 |
P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00002670 | 1 / 0 |
P25021 | Histamine H2 receptor | Histamine receptor | C00002670 | 0 / 0 |
P22303 | Acetylcholinesterase | Hydrolase | C00002670 | 1 / 0 |
P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00002670 | 0 / 0 |
P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00002670 | 0 / 0 |
P35372 | Mu-type opioid receptor | Opioid receptor | C00002670 | 0 / 0 |
P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00002670 | 0 / 0 |
P25103 | Substance-P receptor | Neurokinin receptor | C00002670 | 0 / 0 |
P25105 | Platelet-activating factor receptor | PAF receptor | C00002670 | 0 / 0 |
P53350 | Serine/threonine-protein kinase PLK1 | PLK serine/threonine protein kinase subfamily | C00011153 | 0 / 0 |
P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00002670 | 0 / 0 |
Q02880 | DNA topoisomerase 2-beta | Isomerase | C00011153 | 0 / 0 |
P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00002670 | 1 / 1 |
P31749 | RAC-alpha serine/threonine-protein kinase | Akt | C00011153 | 4 / 1 |
P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00002670 | 0 / 1 |
P68400 | Casein kinase II subunit alpha | Ck2 | C00011153 | 0 / 0 |
P10828 | Thyroid hormone receptor beta | NR1A2 | C00011153 | 3 / 1 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002670 | 0 / 1 |
P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00002670 | 0 / 0 |
P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret | Ret | C00011153 | 9 / 4 |
Q13315 | Serine-protein kinase ATM | Atypical serine/threonine protein kinase PIKK subfamily | C00011153 | 1 / 4 |
O14965 | Aurora kinase A | Aur | C00011153 | 0 / 0 |
Q8N1Q1 | Carbonic anhydrase 13 | Lyase | C00011153 | 0 / 0 |
P14780 | Matrix metalloproteinase-9 | M10A | C00002670 | 2 / 2 |
P27361 | Mitogen-activated protein kinase 3 | Erk | C00002670 | 0 / 0 |
P29466 | Caspase-1 | C14 | C00002670 | 0 / 0 |
P10275 | Androgen receptor | NR3C4 | C00002670 | 3 / 4 |
P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00002670 | 1 / 1 |
P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00002670 | 0 / 0 |
P30542 | Adenosine receptor A1 | Adenosine receptor | C00002670 | 0 / 0 |
P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00002670 | 0 / 0 |
P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00002670 | 1 / 1 |
P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00002670 | 0 / 0 |
P06239 | Tyrosine-protein kinase Lck | Src | C00002670 | 0 / 1 |
P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00002670 | 0 / 0 |
Q13627 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | CMGC dual-specificity kinase DYRK1 | C00011153 | 1 / 0 |
Q16539 | Mitogen-activated protein kinase 14 | p38 | C00002670 | 0 / 0 |
Q13093 | Platelet-activating factor acetylhydrolase | Enzyme | C00002647 | 3 / 0 |
P11142 | Heat shock cognate 71 kDa protein | Unclassified protein | C00011153 | 0 / 0 |
P33765 | Adenosine receptor A3 | Adenosine receptor | C00002670 | 0 / 0 |
P08246 | Neutrophil elastase | S1A | C00002670 | 2 / 1 |
P08069 | Insulin-like growth factor 1 receptor | TK tyrosine-protein kinase INSR subfamily | C00011153 | 1 / 3 |
Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00002670 | 2 / 2 |
P55072 | Transitional endoplasmic reticulum ATPase | Unclassified protein | C00002915 | 2 / 1 |
O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00011153 | 1 / 0 |
O00255 | Menin | Unclassified protein | C00011153 | 2 / 5 |
P21728 | D(1A) dopamine receptor | Dopamine receptor | C00002670 | 0 / 0 |
Q16637 | Survival motor neuron protein | Unclassified protein | C00002647 | 4 / 1 |
Q05513 | Protein kinase C zeta type | Iota | C00002915 | 0 / 0 |
Q04759 | Protein kinase C theta type | Delta | C00002915 | 0 / 1 |
Q02156 | Protein kinase C epsilon type | Eta | C00002915 | 0 / 0 |
O94806 | Serine/threonine-protein kinase D3 | Pkd | C00002915 | 0 / 0 |
Q05655 | Protein kinase C delta type | Delta | C00002915 | 0 / 0 |
P05129 | Protein kinase C gamma type | Alpha | C00002915 | 1 / 1 |
P05771 | Protein kinase C beta type | Alpha | C00002915 | 0 / 0 |
P24723 | Protein kinase C eta type | Eta | C00002915 | 1 / 0 |
P41743 | Protein kinase C iota type | Iota | C00002915 | 0 / 0 |
Q15139 | Serine/threonine-protein kinase D1 | Pkd | C00002915 | 0 / 0 |
Q9NSA0 | Solute carrier family 22 member 11 | Transporter | C00011153 | 0 / 0 |
P20248 | Cyclin-A2 | Other cytosolic protein | C00011153 | 0 / 0 |
P78396 | Cyclin-A1 | Other cytosolic protein | C00011153 | 0 / 0 |
P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00011153 | 0 / 0 |
P22694 | cAMP-dependent protein kinase catalytic subunit beta | Pka | C00011153 | 0 / 0 |
P17612 | cAMP-dependent protein kinase catalytic subunit alpha | Pka | C00011153 | 0 / 0 |
P22612 | cAMP-dependent protein kinase catalytic subunit gamma | Pka | C00011153 | 0 / 0 |
P19429 | Troponin I, cardiac muscle | Unclassified protein | C00002915 | 4 / 4 |
P45379 | Troponin T, cardiac muscle | Unclassified protein | C00002915 | 3 / 5 |
P63316 | Troponin C, slow skeletal and cardiac muscles | Other cytosolic protein | C00002915 | 2 / 2 |
Q9UM73 | ALK tyrosine kinase receptor | TKL serine/threonine protein kinase STKR type 1 subfamily | C00011153 | 1 / 1 |
P06748 | Nucleophosmin | Other nuclear protein | C00011153 | 0 / 0 |
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00002670 | 1 / 0 |
Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00002915 | 2 / 1 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00002647
C00002670
C00011153
|
841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00002647
C00002670
|
6622 | SNCA, NACP, PARK1, PARK4, PD1 | synuclein, alpha (non A4 component of amyloid precursor) |
C00002647
C00002670
|
54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00002647
C00002670
|
7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00002647
C00002670
|
5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00002647
C00011153
|
4313 | MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) |
C00002647
C00011153
|
3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00002647
C00011153
|
596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00002647
C00011153
|
2551 | GABPA, E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A, RCH04A07 | GA binding protein transcription factor, alpha subunit 60kDa |
C00002647
|
811 | CALR, CRT, RO, SSA, cC1qR | calreticulin |
C00011153
|
654 | BMP6, VGR, VGR1 | bone morphogenetic protein 6 |
C00011153
|
6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00011153
|
929 | CD14 | CD14 molecule |
C00011153
|
1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00011153
|
1616 | DAXX, BING2, DAP6, EAP1 | death-domain associated protein |
C00011153
|
1676 | DFFA, DFF-45, DFF1, ICAD | DNA fragmentation factor, 45kDa, alpha polypeptide |
C00011153
|
1877 | E4F1, E4F | E4F transcription factor 1 |
C00011153
|
1960 | EGR3, EGR-3, PILOT | early growth response 3 |
C00011153
|
2033 | EP300, KAT3B, RSTS2, p300 | E1A binding protein p300 (EC:2.3.1.48) |
C00011153
|
2060 | EPS15, AF-1P, AF1P, MLLT5 | epidermal growth factor receptor pathway substrate 15 |
C00011153
|
2145 | EZH1, KMT6B | enhancer of zeste homolog 1 (Drosophila) (EC:2.1.1.43) |
C00011153
|
2161 | F12, HAE3, HAEX, HAF | coagulation factor XII (Hageman factor) (EC:3.4.21.38) |
C00011153
|
2260 | FGFR1, BFGFR, CD331, CEK, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD, bFGF-R-1 | fibroblast growth factor receptor 1 (EC:2.7.10.1) |
C00011153
|
2316 | FLNA, ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD | filamin A, alpha |
C00011153
|
2822 | GPLD1, GPIPLD, GPIPLDM, PIGPLD, PIGPLD1 | glycosylphosphatidylinositol specific phospholipase D1 (EC:3.1.4.50) |
C00011153
|
2941 | GSTA4, GSTA4-4, GTA4 | glutathione S-transferase alpha 4 (EC:2.5.1.18) |
C00011153
|
2961 | GTF2E2, FE, TF2E2, TFIIE-B | general transcription factor IIE, polypeptide 2, beta 34kDa |
C00011153
|
2968 | GTF2H4, P52, TFB2, TFIIH | general transcription factor IIH, polypeptide 4, 52kDa |
C00011153
|
3091 | HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
C00011153
|
3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00011153
|
9592 | IER2, ETR101 | immediate early response 2 |
C00011153
|
3485 | IGFBP2, IBP2, IGF-BP53 | insulin-like growth factor binding protein 2, 36kDa |
C00011153
|
3487 | IGFBP4, BP-4, HT29-IGFBP, IBP4, IGFBP-4 | insulin-like growth factor binding protein 4 |
C00011153
|
3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00011153
|
3554 | IL1R1, CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80 | interleukin 1 receptor, type I |
C00011153
|
55 | ACPP, 5'-NT, ACP-3, ACP3, PAP | acid phosphatase, prostate (EC:3.1.3.2 3.1.3.5) |
C00011153
|
3635 | INPP5D, SHIP, SHIP-1, SHIP1, SIP-145, hp51CN | inositol polyphosphate-5-phosphatase, 145kDa (EC:3.1.3.86) |
C00011153
|
10788 | IQGAP2 | IQ motif containing GTPase activating protein 2 |
C00011153
|
10379 | IRF9, IRF-9, ISGF3, ISGF3G, p48 | interferon regulatory factor 9 |
C00011153
|
354 | KLK3, APS, KLK2A1, PSA, hK3 | kallikrein-related peptidase 3 (EC:3.4.21.77) |
C00011153
|
9516 | LITAF, PIG7, SIMPLE, TP53I7 | lipopolysaccharide-induced TNF factor |
C00011153
|
4130 | MAP1A, MAP1L, MTAP1A | microtubule-associated protein 1A |
C00011153
|
23531 | MMD, MMA, MMD1, PAQR11 | monocyte to macrophage differentiation-associated |
C00011153
|
9474 | ATG5, APG5, APG5-LIKE, APG5L, ASP, hAPG5 | autophagy related 5 |
C00011153
|
4780 | NFE2L2, NRF2 | nuclear factor, erythroid 2-like 2 |
C00011153
|
4791 | NFKB2, H2TF1, LYT-10, LYT10, NF-kB2, p105, p52 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
C00011153
|
4826 | NNAT, Peg5 | neuronatin |
C00011153
|
10528 | NOP56, NOL5A, SCA36 | NOP56 ribonucleoprotein |
C00011153
|
4862 | NPAS2, MOP4, PASD4, bHLHe9 | neuronal PAS domain protein 2 |
C00011153
|
9970 | NR1I3, CAR, CAR1, MB67 | nuclear receptor subfamily 1, group I, member 3 |
C00011153
|
8505 | PARG, PARG99 | poly (ADP-ribose) glycohydrolase (EC:3.2.1.143) |
C00011153
|
5320 | PLA2G2A, MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2 | phospholipase A2, group IIA (platelets, synovial fluid) (EC:3.1.1.4) |
C00011153
|
5355 | PLP2, A4, A4LSB | proteolipid protein 2 (colonic epithelium-enriched) |
C00011153
|
5371 | PML, MYL, PP8675, RNF71, TRIM19 | promyelocytic leukemia |
C00011153
|
5467 | PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB | peroxisome proliferator-activated receptor delta |
C00011153
|
5592 | PRKG1, 1, AAT8, PKG, PRKG1B, PRKGR1B, cGK, cGK_1, cGK1, cGKI, cGKI-BETA, cGKI-alpha | protein kinase, cGMP-dependent, type I (EC:2.7.11.12) |
C00011153
|
5764 | PTN, HARP, HBGF8, HBNF, NEGF1 | pleiotrophin |
C00011153
|
5799 | PTPRN2, IA-2beta, IAR, ICAAR, PTPRP, R-PTP-N2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 (EC:3.1.3.48) |
C00011153
|
5901 | RAN, ARA24, Gsp1, TC4 | RAN, member RAS oncogene family |
C00011153
|
8434 | RECK, ST15 | reversion-inducing-cysteine-rich protein with kazal motifs |
C00011153
|
467 | ATF3 | activating transcription factor 3 |
C00011153
|
8490 | RGS5, MST092, MST106, MST129, MSTP032, MSTP092, MSTP106, MSTP129 | regulator of G-protein signaling 5 |
C00011153
|
6319 | SCD, FADS5, MSTP008, SCD1, SCDOS | stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1) |
C00011153
|
4735 | SEPT2, DIFF6, NEDD-5, NEDD5, Pnutl3, hNedd5 | septin 2 |
C00011153
|
6649 | SOD3, EC-SOD | superoxide dismutase 3, extracellular (EC:1.15.1.1) |
C00011153
|
6774 | STAT3, APRF, HIES | signal transducer and activator of transcription 3 (acute-phase response factor) |
C00011153
|
9013 | TAF1C, MGC:39976, SL1, TAFI110, TAFI95 | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
C00011153
|
6938 | TCF12, CRS3, HEB, HTF4, HsT17266, bHLHb20 | transcription factor 12 |
C00011153
|
7015 | TERT, CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT | telomerase reverse transcriptase (EC:2.7.7.49) |
C00011153
|
7019 | TFAM, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3 | transcription factor A, mitochondrial |
C00011153
|
7040 | TGFB1, CED, DPD1, LAP, TGFB, TGFbeta | transforming growth factor, beta 1 |
C00011153
|
7360 | UGP2, UDPG, UDPGP, UDPGP2, UGP1, UGPP1, UGPP2, pHC379 | UDP-glucose pyrophosphorylase 2 (EC:2.7.7.9) |
C00011153
|
7375 | USP4, UNP, Unph | ubiquitin specific peptidase 4 (proto-oncogene) (EC:3.4.19.12) |
C00011153
|
7453 | WARS, GAMMA-2, IFI53, IFP53 | tryptophanyl-tRNA synthetase (EC:6.1.1.2) |
C00011153
|
7704 | ZBTB16, PLZF, ZNF145 | zinc finger and BTB domain containing 16 |
C00011153
|
7750 | ZMYM2, FIM, MYM, RAMP, SCLL, ZNF198 | zinc finger, MYM-type 2 |
C00011153
|
5243 | ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) |
C00002647
|
25 | ABL1, ABL, JTK7, bcr/abl, c-ABL, p150, v-abl | c-abl oncogene 1, non-receptor tyrosine kinase (EC:2.7.10.2) |
C00002647
|
207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00002647
|
338 | APOB, FLDB, LDLCQ4 | apolipoprotein B |
C00002647
|
472 | ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1 | ataxia telangiectasia mutated (EC:2.7.11.1) |
C00002647
|
545 | ATR, FCTCS, FRP1, MEC1, SCKL, SCKL1 | ataxia telangiectasia and Rad3 related (EC:2.7.11.1) |
C00002647
|
581 | BAX, BCL2L4 | BCL2-associated X protein |
C00002647
|
613 | BCR, ALL, BCR1, CML, D22S11, D22S662, PHL | breakpoint cluster region (EC:2.7.11.1) |
C00002647
|
440 | ASNS, TS11 | asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4) |
C00011153
|
898 | CCNE1, CCNE | cyclin E1 |
C00002647
|
998 | CDC42, CDC42Hs, G25K | cell division cycle 42 |
C00002647
|
1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00002647
|
1027 | CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
C00002647
|
1147 | CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16 | conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) |
C00002647
|
7852 | CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM | chemokine (C-X-C motif) receptor 4 |
C00002647
|
429 | ASCL1, ASH1, HASH1, MASH1, bHLHa46 | achaete-scute family bHLH transcription factor 1 |
C00011153
|
356 | FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 | Fas ligand (TNF superfamily, member 6) |
C00002647
|
2972 | BRF1, BRF, BRF-1, GTF3B, TAF3B2, TAF3C, TAFIII90, TF3B90, TFIIIB90, hBRF | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
C00011153
|
2885 | GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2 | growth factor receptor-bound protein 2 |
C00002647
|
3551 | IKBKB, IKK-beta, IKK2, IKKB, NFKBIKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) |
C00002647
|
3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00002647
|
3949 | LDLR, FH, FHC, LDLCQ2 | low density lipoprotein receptor |
C00002647
|
5604 | MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1 | mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) |
C00002647
|
5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00002647
|
5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00002647
|
5599 | MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c | mitogen-activated protein kinase 8 (EC:2.7.11.24) |
C00002647
|
5601 | MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK | mitogen-activated protein kinase 9 (EC:2.7.11.24) |
C00002647
|
4255 | MGMT | O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63) |
C00002647
|
4316 | MMP7, MMP-7, MPSL1, PUMP-1 | matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23) |
C00002647
|
4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00002647
|
4793 | NFKBIB, IKBB, TRIP9 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
C00002647
|
5578 | PRKCA, AAG6, PKC-alpha, PKCA, PRKACA | protein kinase C, alpha (EC:2.7.11.13) |
C00002647
|
5591 | PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350 | protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1) |
C00002647
|
5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00002647
|
5879 | RAC1, Rac-1, TC-25, p21-Rac1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) |
C00002647
|
19412 |
C00002647
|
||
387 | RHOA, ARH12, ARHA, RHO12, RHOH12 | ras homolog family member A |
C00002647
|
388 | RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6 | ras homolog family member B |
C00002647
|
6195 | RPS6KA1, HU-1, MAPKAPK1A, RSK, RSK1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1) |
C00002647
|
9252 | RPS6KA5, MSK1, MSPK1, RLPK | ribosomal protein S6 kinase, 90kDa, polypeptide 5 (EC:2.7.11.1) |
C00002647
|
317 | APAF1, APAF-1, CED4 | apoptotic peptidase activating factor 1 |
C00011153
|
6817 | SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) |
C00002647
|
7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00002647
|
213 | ALB, PRO0883, PRO0903, PRO1341 | albumin |
C00011153
|
7224 | TRPC5, TRP5 | transient receptor potential cation channel, subfamily C, member 5 |
C00002647
|
7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00002647
|
331 | XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 | X-linked inhibitor of apoptosis |
C00002647
|
351 | APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2 | amyloid beta (A4) precursor protein |
C00002670
|
847 | CAT | catalase (EC:1.11.1.6) |
C00002670
|
1312 | COMT | catechol-O-methyltransferase (EC:2.1.1.6) |
C00002670
|
OMIM | preferred title | UniProt |
---|---|---|
#300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
#100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
#202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
#103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
#203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
#606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
#103780 | Alcohol dependence |
P08172
P14416 P31645 |
#613954 | Amyotrophic lateral sclerosis 14, with or without frontotemporal dementia; als14 |
P55072
|
#614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
#300068 | Androgen insensitivity syndrome; ais |
P10275
|
#312300 | Androgen insensitivity, partial; pais |
P10275
|
#600807 | Asthma, susceptibility to |
Q13093
|
#208900 | Ataxia-telangiectasia; at |
Q13315
|
#614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
#615007 | Basal ganglia calcification, idiopathic, 4; ibgc4 |
P09619
|
#613985 | Beta-thalassemia |
P68871
|
#603902 | Beta-thalassemia, dominant inclusion body type |
P68871
|
#601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
#210900 | Bloom syndrome; blm |
P54132
|
#602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
#114480 | Breast cancer |
P31749
|
#300615 | Brunner syndrome |
P21397
|
#115150 | Cardiofaciocutaneous syndrome 1; cfc1 |
P15056
|
#115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
#601494 | Cardiomyopathy, dilated, 1d; cmd1d |
P45379
|
#613286 | Cardiomyopathy, dilated, 1ff; cmd1ff |
P19429
|
#611879 | Cardiomyopathy, dilated, 1z; cmd1z |
P63316
|
#611880 | Cardiomyopathy, dilated, 2a; cmd2a |
P19429
|
#212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
#613243 | Cardiomyopathy, familial hypertrophic, 13; cmh13 |
P63316
|
#115195 | Cardiomyopathy, familial hypertrophic, 2; cmh2 |
P45379
|
#613690 | Cardiomyopathy, familial hypertrophic, 7; cmh7 |
P19429
|
#115210 | Cardiomyopathy, familial restrictive, 1; rcm1 |
P19429
|
#612422 | Cardiomyopathy, familial restrictive, 3; rcm3 |
P45379
|
#209880 | Central hypoventilation syndrome, congenital; cchs |
P07949
|
#605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
#114500 | Colorectal cancer; crc |
P07949
P15056 P31749 P84022 Q14191 |
#615109 | Cowden syndrome 6; cws6 |
P31749
|
#218800 | Crigler-najjar syndrome, type i |
P22309
|
#606785 | Crigler-najjar syndrome, type ii |
P22309
|
#162800 | Cyclic neutropenia |
P08246
|
#612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
#610549 | Diabetes mellitus, insulin-resistant, with acanthosis nigricans |
P06213
|
#125853 | Diabetes mellitus, noninsulin-dependent; niddm |
P06213
|
#119900 | Digital clubbing, isolated congenital |
P15428
|
#246200 | Donohue syndrome |
P06213
|
#609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
#226200 | Enterokinase deficiency |
P98073
|
#133239 | Esophageal cancer |
P04637
|
#615363 | Estrogen resistance; estrr |
P03372
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#613659 | Gastric cancer |
P04626
|
#137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
#231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
#143500 | Gilbert syndrome |
P22309
|
#137800 | Glioma susceptibility 1; glm1 |
O75874
P04626 |
#232300 | Glycogen storage disease ii |
P10253
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#610140 | Heart-hand syndrome, slovenian type |
P02545
|
#140700 | Heinz body anemias |
P68871
|
#602089 | Hemangioma, capillary infantile |
P35916
P35968 |
#614519 | Hemorrhage, intracerebral, susceptibility to; ich |
P12821
|
#114550 | Hepatocellular carcinoma |
P08581
|
#142623 | Hirschsprung disease, susceptibility to, 1; hscr1 |
P07949
|
#609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
#176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
#237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
#143860 | Hyperchlorhidrosis, isolated |
O43570
|
#609968 | Hyperinsulinemic hypoglycemia, familial, 5; hhf5 |
P06213
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
#147050 | Ige responsiveness, atopic; iger |
Q13093
|
#167320 | Inclusion body myopathy with early-onset paget disease with or without frontotemporal dementia 1; ibmpfd1 |
P55072
|
#614328 | Inflammatory skin and bowel disease, neonatal; nisbd |
P78536
|
#270450 | Insulin-like growth factor i, resistance to |
P08069
|
#603932 | Intervertebral disc disease; idd |
P14780
|
#607785 | Juvenile myelomonocytic leukemia; jmml |
P09619
|
#613707 | Leopard syndrome 3 |
P15056
|
#601626 | Leukemia, acute myeloid; aml |
P09619
P36888 |
#151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
#151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
#613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
#613688 | Long qt syndrome 2; lqt2 |
Q12809
|
#211980 | Lung cancer |
P00533
P04626 P04637 P15056 |
#153100 | Lymphedema, hereditary, ia |
P35916
|
#605027 | Lymphoma, non-hodgkin, familial |
P15056
|
#608516 | Major depressive disorder; mdd |
P08172
|
#248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
#609048 | Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 |
P11802
|
#614104 | Mental retardation, autosomal dominant 7; mrd7 |
Q13627
|
#300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
%300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
#300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
#613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
#612624 | Microvascular complications of diabetes, susceptibility to, 3; mvcd3 |
P12821
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#171400 | Multiple endocrine neoplasia, type iia; men2a |
P07949
|
#162300 | Multiple endocrine neoplasia, type iib; men2b |
P07949
|
#126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
#613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
#159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
#607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
#254500 | Myeloma, multiple |
P24385
|
#131440 | Myeloproliferative disorder, chronic, with eosinophilia |
P09619
|
#159900 | Myoclonic dystonia |
P14416
|
#228550 | Myofibromatosis, infantile, 1; imf1 |
P09619
|
#160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
#613014 | Neuroblastoma, susceptibility to, 3; nblst3 |
Q9UM73
|
#202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
#257200 | Niemann-pick disease, type a |
P17405
|
#607616 | Niemann-pick disease, type b |
P17405
|
#613706 | Noonan syndrome 7; ns7 |
P15056
|
#601665 | Obesity |
P32245
|
#164230 | Obsessive-compulsive disorder; ocd |
P31645
|
#604715 | Orthostatic intolerance |
P23975
|
#259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
#167000 | Ovarian cancer |
P04626
|
#260500 | Papilloma of choroid plexus; cpp |
P04637
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
#171300 | Pheochromocytoma |
P07949
|
#172700 | Pick disease of brain |
P10636
|
#262190 | Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities |
P06213
|
#601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
#614278 | Platelet-activating factor acetylhydrolase deficiency; pafad |
Q13093
|
#176920 | Proteus syndrome |
P31749
|
#191830 | Renal adysplasia |
P07949
|
#605074 | Renal cell carcinoma, papillary, 1; rccp1 |
P08581
|
#267430 | Renal tubular dysgenesis; rtd |
P12821
|
#607276 | Resting heart rate, variation in |
P08588
|
#275210 | Restrictive dermopathy, lethal |
P02545
|
#600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
#604906 | Schizophrenia 9; sczd9 |
P49798
|
#181500 | Schizophrenia; sczd |
P49798
|
#608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
#609620 | Short qt syndrome 1; sqt1 |
Q12809
|
#603903 | Sickle cell anemia |
P68871
|
#601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
#313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
#253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
#253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
#253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
#271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
#605361 | Spinocerebellar ataxia 14; sca14 |
P05129
|
#607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
#275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
#601367 | Stroke, ischemic |
P12821
P16109 P24723 |
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#155240 | Thyroid carcinoma, familial medullary; mtc |
P07949
|
#188550 | Thyroid carcinoma, papillary |
P07949
|
#188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
#274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
#145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
#190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
#600195 | Venous malformations, multiple cutaneous and mucosal; vmcm |
Q02763
|
#277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
#277700 | Werner syndrome; wrn |
Q14191
|
#610379 | West nile virus, susceptibility to |
P51681
|
#278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
#112100 | Yt blood group antigen |
P22303
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
H00021 | Renal cell carcinoma |
O43570
(marker)
P04637 (marker) P08581 (related) Q16790 (marker) |
H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) P24385 (related) P24385 (marker) |
H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P24385 (related) P35354 (related) |
H00018 | Gastric cancer |
P00533
(related)
P04626 (related) P04637 (related) P08581 (related) |
H00022 | Bladder cancer |
P00533
(related)
P04626 (related) P04637 (related) P68871 (marker) |
H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) P04637 (related) |
H00030 | Cervical cancer |
P00533
(related)
P04626 (related) P11802 (related) |
H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) P09619 (related) P11802 (related) |
H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) P24385 (related) P24385 (marker) |
H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
H00436 | Osteopetrosis |
P00918
(related)
|
H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
P19429 (related) P45379 (related) P63316 (related) |
H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
H00663 | Restrictive dermopathy |
P02545
(related)
|
H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
P45379 (related) |
H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) P04637 (related) Q92731 (marker) |
H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
H00019 | Pancreatic cancer |
P04626
(related)
P04637 (related) P04637 (marker) |
H00027 | Ovarian cancer |
P04626
(related)
P04637 (related) |
H00031 | Breast cancer |
P04626
(related)
P04626 (marker) P04637 (related) P24385 (related) |
H00046 | Cholangiocarcinoma |
P04626
(related)
P04637 (related) P08581 (related) P35354 (related) |
H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
Q13315 (related) |
H00006 | Hairy-cell leukemia |
P04637
(related)
P24385 (related) |
H00008 | Burkitt lymphoma |
P04637
(related)
|
H00009 | Adult T-cell leukemia |
P04637
(related)
|
H00010 | Multiple myeloma |
P04637
(related)
P24385 (related) |
H00013 | Small cell lung cancer |
P04637
(related)
|
H00014 | Non-small cell lung cancer |
P04637
(related)
Q9UM73 (related) |
H00015 | Malignant pleural mesothelioma |
P04637
(related)
P08069 (related) |
H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) P68871 (marker) |
H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P14780 (related) P35354 (related) |
H00029 | Vulvar cancer |
P04637
(related)
|
H00032 | Thyroid cancer |
P04637
(related)
P07949 (related) P07949 (marker) P15056 (related) |
H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
H00038 | Malignant melanoma |
P04637
(related)
P11802 (related) P14679 (marker) P15056 (related) |
H00039 | Basal cell carcinoma |
P04637
(related)
|
H00040 | Squamous cell carcinoma |
P04637
(related)
|
H00041 | Kaposi's sarcoma |
P04637
(related)
|
H00044 | Cancer of the anal canal |
P04637
(related)
|
H00047 | Gallbladder cancer |
P04637
(related)
P24385 (marker) |
H00048 | Hepatocellular carcinoma |
P04637
(related)
|
H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
H01007 | Choroid plexus papilloma |
P04637
(related)
|
H00063 | Spinocerebellar ataxia (SCA) |
P05129
(related)
Q9NUW8 (related) |
H00719 | Leprechaunism |
P06213
(related)
|
H00942 | Rabson-Mendenhall syndrome |
P06213
(related)
|
H01228 | Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN) |
P06213
(related)
|
H01267 | Familial hyperinsulinemic hypoglycemia (HHF) |
P06213
(related)
|
H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
H00079 | Asthma |
P07550
(related)
|
H00822 | Renal agenesis and Renal adysplasia |
P07949
(related)
|
H00910 | Hirschsprung disease (HD) |
P07949
(related)
|
H00916 | Congenital central hypoventilation syndrome (CCHS) |
P07949
(related)
|
H00050 | Synovial sarcoma |
P08069
(related)
|
H01274 | Growth delay due to insulin-like growth factor I resistance |
P08069
(related)
|
H00100 | Neutropenic disorders |
P08246
(related)
|
H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
H00024 | Prostate cancer |
P09211
(related)
P09211 (marker) P10275 (related) |
H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
P55072 (related) |
H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
H00342 | Tuberculosis |
P11473
(related)
|
H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
H01205 | Coumarin resistance |
P11712
(related)
|
H00083 | Allograft rejection |
P12821
(related)
|
H00575 | Renal tubular dysgenesis |
P12821
(related)
|
H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
H00479 | Metaphyseal dysplasias |
P14780
(related)
|
H00523 | Noonan syndrome and related disorders |
P15056
(related)
|
H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
H00292 | Hypertrophic cardiomyopathy (HCM) |
P19429
(related)
P45379 (related) P63316 (related) |
H01219 | Restrictive cardiomyopathy (RCM) |
P19429
(related)
P45379 (related) |
H00295 | Viral myocarditis |
P19429
(marker)
P45379 (marker) |
H00548 | Brunner syndrome |
P21397
(related)
|
H00208 | Hyperbilirubinemia |
P22309
(related)
|
H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
H00559 | von Hippel-Lindau syndrome |
P24385
(related)
|
H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
H00539 | PTEN hamartoma tumor syndrome (PHTS) |
P31749
(related)
|
H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
H00535 | Lymphedemas |
P35916
(related)
|
H00003 | Acute myeloid leukemia (AML) |
P36888
(related)
Q01196 (related) Q01196 (marker) Q13951 (marker) |
H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
Q99714 (related) |
H00094 | DNA repair defects |
P54132
(related)
Q13315 (related) |
H00296 | Defects in RecQ helicases |
P54132
(related)
Q14191 (related) |
H00228 | Thalassemia |
P68871
(related)
|
H00229 | Sickle cell anemia (SCA) |
P68871
(related)
|
H00988 | Enterokinase deficiency |
P98073
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
H00531 | Venous malformations |
Q02763
(related)
|
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00408 | Type I diabetes mellitus |
Q04759
(related)
|
H00720 | Long QT syndrome |
Q12809
(related)
|
H00725 | Short QT syndrome |
Q12809
(related)
|
H00064 | Ataxia telangiectasia (AT) |
Q13315
(related)
|
H00848 | Ataxia with ocular apraxia (AOA) |
Q13315
(related)
|
H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
MESH or OMIM | name |
KNApSAcK
metabolite |
---|---|---|
D009203 | Myocardial Infarction |
C00011153
C00002647 |
D006937 | Hypercholesterolemia |
C00002647
|
D006965 | Hyperplasia |
C00011153
|
D007248 | Infertility, Male |
C00011153
|
D000014 | Abnormalities, Drug-Induced |
C00011153
|
D015427 | Reperfusion Injury |
C00011153
|
D012878 | Skin Neoplasms |
C00011153
|
D013471 | Sunburn |
C00011153
|
D013733 | Testicular Diseases |
C00011153
|
D003921 | Diabetes Mellitus, Experimental |
C00002647
|
D050171 | Dyslipidemias |
C00002647
|
D005234 | Fatty Liver |
C00002647
|
D018149 | Glucose Intolerance |
C00002647
|
D002471 | Cell Transformation, Neoplastic |
C00011153
|
D006943 | Hyperglycemia |
C00002647
|
D006949 | Hyperlipidemias |
C00002647
|
D015228 | Hypertriglyceridemia |
C00002647
|
D015464 | Leukemia, Myelogenous, Chronic, BCR-ABL Positive |
C00002647
|
D008546 | Melanoma, Experimental |
C00002647
|
D009069 | Movement Disorders |
C00002647
|
D009361 | Neoplasm Invasiveness |
C00002647
|
D009362 | Neoplasm Metastasis |
C00002647
|
D012516 | Osteosarcoma |
C00002647
|
D010182 | Pancreatic Diseases |
C00002647
|
D056486 | Drug-Induced Liver Injury |
C00002670
|
D048629 | Micronuclei, Chromosome-Defective |
C00002670
|