KCF-S cluster No. 226 (28 metabolites)

Corresponding Phytochemical cluster No. 81

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (28)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	82
eudicotyledons	3
asterids	1

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Cumulative family count (Top 20)

class name	count
Melastomataceae	16
Euphorbiaceae	9
Myrtaceae	9
Rosaceae	9
Casuarinaceae	7
Phyllanthaceae	5
Geraniaceae	5
Stachyuraceae	4
Fagaceae	4
Fabaceae	2
Combretaceae	2
Juglandaceae	2
Halichondriidae	2
Coriariaceae	1
Erythroxylaceae	1
Onagraceae	1
Cunoniaceae	1
Cercidiphyllaceae	1
Aceraceae	1
Cornaceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Ellagitannins	9

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metabolites link (9)

br08003 Category	KEGG ID	KNApSAcK ID
Ellagitannins	C10211	C00002908
Ellagitannins	C10212	C00002909
Ellagitannins	C10213	C00002910
Ellagitannins	C10214	C00002911
Ellagitannins	C10215	C00002912
Ellagitannins	C10230	C00002926
Ellagitannins	C10232	C00002928
Ellagitannins	C10235	C00002931
Ellagitannins	C10236	C00002932

Metabolite list (28)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002908	Alnusiin
C00002909	Casuarictin	CHEMBL305099 CHEMBL446979	C073064
C00002910	Casuarinin	CHEMBL79244 CHEMBL507387		11 / 2 / 2
C00002911	Chebulagic acid	CHEMBL525240 CHEMBL1970427	C076178	12 / 2 / 2
C00002912	Chebulinic acid	CHEMBL501154 CHEMBL1159459 CHEMBL1391063	C103481	29 / 15 / 14	6 / 0
C00002926	Geraniin	CHEMBL506069	C024603	1 / 4 / 2	0 / 1
C00002928	Isoterchebin
C00002931	Mallotusinic acid
C00002932	Pedunculagin	CHEMBL292719 CHEMBL506204		1 / 1 / 0
C00031107	Pterocarinin A
C00032196	Stachyurin	CHEMBL79244 CHEMBL507387		11 / 2 / 2
C00035321	Geraniinic acid B
C00035322	Geraniinic acid C
C00035366	Phyllanthusiin A
C00035367	Phyllanthusiin B
C00035368	Phyllanthusiin D
C00037605	Pelargoniin A
C00040861	Acalyphidin M2
C00041050	Mallotusinin
C00042346	Castalagin	CHEMBL288949 CHEMBL288273 CHEMBL504485 CHEMBL607711		11 / 2 / 2
C00043104	Vescalagin	CHEMBL288949 CHEMBL288273 CHEMBL504485 CHEMBL607711	C084709	11 / 2 / 2
C00044999	Paeonianin E
C00046303	Phyllanemblinin C	CHEMBL501660
C00048812	Phenazine A
C00048813	Phenazine B
C00049290	Carpinerin B / Rhoipteleanin H
C00049958	5'-Desgalloylstachyurin	CHEMBL509562 CHEMBL488110		1 / 1 / 0
C00050033	Casuariin	CHEMBL509562 CHEMBL488110		1 / 1 / 0

Human Protein / Gene in interactions

32 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q15139	Serine/threonine-protein kinase D1	Pkd	C00002910 C00002911 C00002912 C00032196 C00042346 C00043104	0 / 0
P41743	Protein kinase C iota type	Iota	C00002910 C00002911 C00002912 C00032196 C00042346 C00043104	0 / 0
P24723	Protein kinase C eta type	Eta	C00002910 C00002911 C00002912 C00032196 C00042346 C00043104	1 / 0
P05771	Protein kinase C beta type	Alpha	C00002910 C00002911 C00002912 C00032196 C00042346 C00043104	0 / 0
P05129	Protein kinase C gamma type	Alpha	C00002910 C00002911 C00002912 C00032196 C00042346 C00043104	1 / 1
Q05655	Protein kinase C delta type	Delta	C00002910 C00002911 C00002912 C00032196 C00042346 C00043104	0 / 0
Q05513	Protein kinase C zeta type	Iota	C00002910 C00002911 C00002912 C00032196 C00042346 C00043104	0 / 0
O94806	Serine/threonine-protein kinase D3	Pkd	C00002910 C00002911 C00002912 C00032196 C00042346 C00043104	0 / 0
Q02156	Protein kinase C epsilon type	Eta	C00002910 C00002911 C00002912 C00032196 C00042346 C00043104	0 / 0
Q04759	Protein kinase C theta type	Delta	C00002910 C00002911 C00002912 C00032196 C00042346 C00043104	0 / 1
P17252	Protein kinase C alpha type	Alpha	C00002910 C00002911 C00002912 C00032196 C00042346 C00043104	0 / 0
P00742	Coagulation factor X	S1A	C00002932 C00049958 C00050033	1 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002912	0 / 0
P12821	Angiotensin-converting enzyme	M2	C00002926	4 / 2
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00002912	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00002912	4 / 3
P28482	Mitogen-activated protein kinase 1	Erk	C00002912	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00002912	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002912	1 / 1
Q13951	Core-binding factor subunit beta	Unclassified protein	C00002912	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00002912	1 / 4
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002912	1 / 2
P11387	DNA topoisomerase 1	Isomerase	C00002911	0 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00002912	1 / 0
P54132	Bloom syndrome protein	Enzyme	C00002912	1 / 2
P10828	Thyroid hormone receptor beta	NR1A2	C00002912	3 / 1
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00002912	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00002912	1 / 1
P06746	DNA polymerase beta	Enzyme	C00002912	0 / 0
P14618	Pyruvate kinase PKM	Enzyme	C00002912	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00002912	0 / 0
Q07820	Induced myeloid leukemia cell differentiation protein Mcl-1	Other cytosolic protein	C00002912	0 / 0

6 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
43	ACHE, ACEE, ARACHE, N-ACHE, YT	acetylcholinesterase (EC:3.1.1.7)	C00002912
2623	GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT	GATA binding protein 1 (globin transcription factor 1)	C00002912
2624	GATA2, DCML, MONOMAC, NFE1B	GATA binding protein 2	C00002912
2993	GYPA, CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN, MNS, PAS-2	glycophorin A (MNS blood group)	C00002912
3145	HMBS, PBG-D, PBGD, PORC, UPS	hydroxymethylbilane synthase (EC:2.5.1.61)	C00002912
4778	NFE2, NF-E2, p45	nuclear factor, erythroid 2	C00002912

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions