Posidonia oceanica

• Index
• Plant Species
• Metabolite list (21)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Posidonia oceanica
Genus	Posidonia
Family	Posidoniaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Posidonia oceanica
Linked NCBI taxonomy ID	55489
Linked level	species

Family

Family in NCBI taxonomy	Posidoniaceae
ID	55435

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	Liliopsida
ID	4447

Metabolite list (21)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00002668	Protocatechuic acid / 3,4-Dihydroxybenzoic acid	CHEMBL37537	C009091	33 / 19 / 19	2 / 0	No. 817	No. 81
C00000856	4-Hydroxybenzoic acid / p-Hydroxybenzoic acid	CHEMBL441343	C038193	21 / 7 / 16	2 / 1	No. 817	No. 81
C00002647	Gallic acid	CHEMBL288114	D005707	42 / 53 / 68	52 / 16	No. 817	No. 81
C00007558	Syringaldehyde / 4-Hydroxy-3,5-dimethoxybenzaldehyde	CHEMBL225303	C069665			No. 856
C00000615	Caffeic acid	CHEMBL145 CHEMBL1320034		68 / 64 / 63		No. 904	No. 6
C00029961	Cinnamic acid / .beta-Phenylacrylic acid	CHEMBL27246	C029010	5 / 2 / 2	16 / 2	No. 904	No. 6
C00002683	Vanillin	CHEMBL13883		18 / 8 / 9		No. 1003
C00002682	Vanillic acid / 3-Methoxy-4-hydroxybenzoic acid	CHEMBL120568	D014641	5 / 3 / 3	5 / 0	No. 1073
C00002674	Syringic acid / 4-Hydroxy-3,5-dimethoxybenzoic acid	CHEMBL1414	C001945	12 / 3 / 5		No. 1073
C00002686	Acetosyringone	CHEMBL224146	C051667	3 / 11 / 10		No. 1180
C00002776	Sinapic acid	CHEMBL109341	C073734	5 / 5 / 5	0 / 5	No. 1366	No. 6
C00002743	Ferulic acid / 3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid	CHEMBL32749	C004999	110 / 52 / 40	16 / 6	No. 1366	No. 6
C00002689	Apocynin / Acetovanillone	CHEMBL346919	C056165	2 / 0 / 0	43 / 10	No. 1494
C00002670	Pyrogallol	CHEMBL307145	D011748	115 / 69 / 60	8 / 2	No. 1590	No. 82
C00002644	Catechol / Pyrocatechol	CHEMBL280998	C034221	148 / 82 / 64	22 / 5	No. 1590	No. 82
C00002665	Phloroglucinol	CHEMBL473159	D010696	3 / 4 / 2	8 / 2	No. 1590	No. 82
C00002657	p-Formylphenol / 4-Hydroxybenzaldehyde / p-Hydroxybenzaldehyde	CHEMBL14193	C011483	3 / 2 / 2		No. 2076
C00018099	Catechaldehyde / Protocatechualdehyde / 3,4-Dihydroxybenzaldehyde	CHEMBL222021	C005581	7 / 0 / 0	5 / 2	No. 2076
C00000207	Benzoic acid	CHEMBL541	D019817	97 / 39 / 33	24 / 1	No. 2192
C00029536	p-Anisic acid / 4-Methoxybenzoic acid	CHEMBL21932	C004520	3 / 2 / 3		No. 2930
C00002664	Phenol	CHEMBL14060	D019800	111 / 52 / 47	101 / 30	No. 6006

Human Protein / Gene in interactions

217 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P00918	Carbonic anhydrase 2	Lyase	C00000207 C00000615 C00000856 C00002644 C00002647 C00002664 C00002668 C00002670 C00002674 C00002743 C00029536	1 / 2
P00915	Carbonic anhydrase 1	Lyase	C00000615 C00000856 C00002644 C00002647 C00002664 C00002668 C00002670 C00002674 C00002743 C00029536	0 / 0
P03372	Estrogen receptor	NR3A1	C00000207 C00000615 C00002644 C00002647 C00002664 C00002668 C00002670 C00002682 C00002743 C00029961	1 / 1
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00000615 C00002644 C00002647 C00002668 C00002670 C00002683 C00002686 C00002776 C00018099	0 / 0
P23280	Carbonic anhydrase 6	Lyase	C00000615 C00000856 C00002644 C00002647 C00002664 C00002668 C00002670 C00002674 C00002743	0 / 0
P22748	Carbonic anhydrase 4	Lyase	C00000615 C00000856 C00002644 C00002647 C00002664 C00002668 C00002674 C00002743	1 / 1
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000207 C00000615 C00002644 C00002647 C00002664 C00002670 C00002743 C00002776	0 / 3
O43570	Carbonic anhydrase 12	Lyase	C00000615 C00000856 C00002644 C00002647 C00002664 C00002668 C00002674 C00002743	1 / 2
P43166	Carbonic anhydrase 7	Lyase	C00000615 C00000856 C00002644 C00002647 C00002664 C00002668 C00002674 C00002743	0 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00000615 C00000856 C00002644 C00002647 C00002664 C00002668 C00002674 C00002743	0 / 1
Q9ULX7	Carbonic anhydrase 14	Lyase	C00000615 C00000856 C00002644 C00002647 C00002664 C00002668 C00002674 C00002743	0 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000207 C00000615 C00002644 C00002664 C00002670 C00002743 C00002776	0 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00000207 C00000615 C00000856 C00002644 C00002664 C00002670 C00002743	1 / 8
P03956	Interstitial collagenase	M10A	C00000207 C00000615 C00002644 C00002664 C00002668 C00002670 C00002743	0 / 1
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00000615 C00000856 C00002644 C00002647 C00002664 C00002674 C00002743	0 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00000615 C00000856 C00002644 C00002647 C00002664 C00002674 C00002743	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00000207 C00000615 C00002644 C00002664 C00002668 C00002670 C00002743	2 / 2
P28482	Mitogen-activated protein kinase 1	Erk	C00000207 C00000615 C00002644 C00002647 C00002664 C00002670 C00002743	0 / 0
P07451	Carbonic anhydrase 3	Lyase	C00000615 C00000856 C00002644 C00002647 C00002664 C00002674 C00002743	0 / 0
P15121	Aldose reductase	Enzyme	C00000615 C00002647 C00002668 C00002674 C00002682 C00029961	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00000207 C00002644 C00002647 C00002664 C00002670 C00002743	0 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000207 C00000615 C00002644 C00002664 C00002670 C00002743	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00000615 C00002644 C00002647 C00002668 C00002743 C00018099	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000207 C00000615 C00002644 C00002664 C00002670 C00002743	0 / 1
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00000615 C00002644 C00002647 C00002664 C00002670 C00002683	1 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000207 C00000615 C00002644 C00002664 C00002670 C00002743	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000207 C00000615 C00002644 C00002664 C00002670 C00002743	0 / 1
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00000207 C00000615 C00002644 C00002664 C00002670 C00002743	2 / 2
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000207 C00000615 C00002644 C00002664 C00002670 C00002743	1 / 0
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P29466	Caspase-1	C14	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00000207 C00002644 C00002664 C00002670 C00002743	1 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000615 C00002644 C00002647 C00002670 C00018099	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00000615 C00002644 C00002647 C00002670 C00002686	11 / 10
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00000615 C00002644 C00002647 C00002665 C00002670	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00000615 C00002644 C00002647 C00002670 C00002683	2 / 2
P33032	Melanocortin receptor 5	Melanocortin receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00000207 C00002644 C00002664 C00002670 C00002743	1 / 1
P25021	Histamine H2 receptor	Histamine receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00000207 C00002644 C00002664 C00002670 C00002743	1 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00000207 C00002644 C00002664 C00002670 C00002743	1 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00000207 C00002644 C00002664 C00002670 C00002743	2 / 1
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00000207 C00002644 C00002664 C00002670 C00002743	1 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00000207 C00002644 C00002664 C00002670 C00002743	3 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P06239	Tyrosine-protein kinase Lck	Src	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 1
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00000207 C00002644 C00002664 C00002670 C00002743	1 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00000207 C00002644 C00002664 C00002670 C00002743	5 / 9
P31645	Sodium-dependent serotonin transporter	Serotonin	C00000207 C00002644 C00002664 C00002670 C00002743	2 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00000207 C00002644 C00002664 C00002670 C00002743	2 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
Q13093	Platelet-activating factor acetylhydrolase	Enzyme	C00000615 C00002647 C00002668 C00002743 C00002776	3 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00000207 C00002644 C00002664 C00002670 C00002743	1 / 1
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00000207 C00002644 C00002664 C00002670 C00002743	1 / 1
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00000207 C00002644 C00002664 C00002670 C00002743	1 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00000615 C00002644 C00002647 C00002670 C00002683	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00000207 C00002644 C00002664 C00002670 C00002743	1 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00000207 C00002644 C00002664 C00002670 C00002743	1 / 1
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00000207 C00002644 C00002664 C00002670 C00002743	2 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002644 C00002647 C00002664 C00002670 C00002683	0 / 0
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
O75496	Geminin	Unclassified protein	C00002644 C00002668 C00002686 C00002689 C00002743	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00000207 C00002644 C00002664 C00002670 C00002743	1 / 0
P08311	Cathepsin G	S1A	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00000207 C00002644 C00002664 C00002670 C00002743	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P08246	Neutrophil elastase	S1A	C00000207 C00002644 C00002664 C00002670 C00002743	2 / 1
P25101	Endothelin-1 receptor	Endothelin receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00000207 C00002644 C00002664 C00002670 C00002743	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00000615 C00002665 C00002670 C00002743	4 / 2
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00000615 C00002644 C00002743 C00029961	1 / 1
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00000207 C00000856 C00002664 C00002683	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00000615 C00002644 C00002647 C00002670	3 / 3
Q9UNA4	DNA polymerase iota	Enzyme	C00002644 C00002668 C00002682 C00018099	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00000615 C00002644 C00002647 C00002670	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00000615 C00002644 C00002647 C00002668	4 / 3
P08253	72 kDa type IV collagenase	M10A	C00000615 C00002644 C00002668	1 / 3
O75164	Lysine-specific demethylase 4A	Enzyme	C00000615 C00002644 C00018099	0 / 0
P51649	Succinate-semialdehyde dehydrogenase, mitochondrial	Oxidoreductase	C00000856 C00002657 C00002683	1 / 1
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00002647 C00002670 C00002743	5 / 1
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00000615 C00002644 C00002668	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00000207 C00000856 C00002683	0 / 0
P51580	Thiopurine S-methyltransferase	Enzyme	C00000856 C00002682 C00029536	1 / 1
P14151	L-selectin	Adhesion	C00002647 C00002668 C00002670	0 / 0
P10275	Androgen receptor	NR3C4	C00002664 C00002670 C00002683	3 / 4
Q8TDS4	Hydroxycarboxylic acid receptor 2	Hydroxycarboxylic acid receptor	C00000615 C00002743 C00029961	0 / 0
P16109	P-selectin	Adhesion	C00002647 C00002668 C00002670	1 / 0
P16581	E-selectin	Adhesion	C00002647 C00002668 C00002670	0 / 0
P06746	DNA polymerase beta	Enzyme	C00000615 C00002644 C00002668	0 / 0
Q9GZT9	Egl nine homolog 1	Enzyme	C00000615 C00002644 C00002668	1 / 1
P80404	4-aminobutyrate aminotransferase, mitochondrial	Transferase	C00000856 C00002657 C00002683	1 / 1
P10145	Interleukin-8	Secreted protein	C00002644 C00002647 C00002670	0 / 0
Q9HAW7	UDP-glucuronosyltransferase 1-7	Enzyme	C00000856 C00002683	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00002644 C00002664	5 / 3
P11473	Vitamin D3 receptor	NR1I1	C00002647 C00002670	2 / 3
P08254	Stromelysin-1	M10A	C00002644 C00002668	1 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00000615 C00029961	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00000615 C00002664	1 / 1
Q96RI1	Bile acid receptor	NR1H4	C00002644 C00002683	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00000615 C00002644	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00000615 C00018099	0 / 0
Q12794	Hyaluronidase-1	Enzyme	C00000615 C00002743	1 / 2
Q16637	Survival motor neuron protein	Unclassified protein	C00002644 C00002647	4 / 1
P02768	Serum albumin	Secreted protein	C00002668 C00002670	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00002644 C00002670	0 / 0
P34969	5-hydroxytryptamine receptor 7	Serotonin receptor	C00002683 C00002743	0 / 0
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00000856 C00002683	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00002644 C00002689	0 / 0
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00002644 C00002668	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00000615 C00002668	1 / 1
P51151	Ras-related protein Rab-9A	Unclassified protein	C00002644 C00018099	0 / 0
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00002664 C00002683	0 / 0
Q01453	Peripheral myelin protein 22	Unclassified protein	C00000615 C00002644	5 / 2
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00002670 C00002743	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00000207 C00000615	3 / 2
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00002644 C00002670	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00002668 C00002670	0 / 1
P22894	Neutrophil collagenase	M10A	C00002644 C00002668	0 / 0
Q01196	Runt-related transcription factor 1	Unclassified protein	C00002668 C00002670	1 / 4
Q9UQ49	Sialidase-3	Enzyme	C00000207 C00000856	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00000615 C00002644	0 / 0
P12821	Angiotensin-converting enzyme	M2	C00002647	4 / 2
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00000207	0 / 0
Q9Y4X1	UDP-glucuronosyltransferase 2A1	Enzyme	C00002683	0 / 0
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00000856	0 / 0
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00002644	0 / 0
O15118	Niemann-Pick C1 protein	Unclassified protein	C00002644	1 / 1
Q04828	Aldo-keto reductase family 1 member C1	Enzyme	C00000615	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00002644	1 / 1
P56817	Beta-secretase 1	A1A	C00002665	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00002644	2 / 0
P35236	Tyrosine-protein phosphatase non-receptor type 7	Tyr	C00000615	0 / 0
P08581	Hepatocyte growth factor receptor	TK tyrosine-protein kinase MET subfamily	C00002647	2 / 3
O60218	Aldo-keto reductase family 1 member B10	Enzyme	C00000615	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00002644	0 / 0
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00002644	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00002644	1 / 1
P52895	Aldo-keto reductase family 1 member C2	Enzyme	C00000615	1 / 0
Q9GZT4	Serine racemase	Enzyme	C00000207	0 / 0
O00519	Fatty-acid amide hydrolase 1	Enzyme	C00002683	0 / 0
P07711	Cathepsin L1	C1A	C00002668	0 / 0
P42858	Huntingtin	Unclassified protein	C00002682	1 / 1
Q99549	M-phase phosphoprotein 8	Unclassified protein	C00002644	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00002647	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00002644	0 / 0
P14902	Indoleamine 2,3-dioxygenase 1	Enzyme	C00002657	0 / 0
P42330	Aldo-keto reductase family 1 member C3	Enzyme	C00000615	0 / 0
P17516	Aldo-keto reductase family 1 member C4	Enzyme	C00000615	1 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00002776	2 / 2
P78527	DNA-dependent protein kinase catalytic subunit	Atypical serine/threonine protein kinase PIKK subfamily	C00002683	0 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00002644	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00002647	7 / 37
P54132	Bloom syndrome protein	Enzyme	C00002644	1 / 2
P14920	D-amino-acid oxidase	Enzyme	C00000207	0 / 0
P78536	Disintegrin and metalloproteinase domain-containing protein 17	M12B	C00002647	1 / 0
P04066	Tissue alpha-L-fucosidase	Enzyme	C00002664	1 / 2
P51452	Dual specificity protein phosphatase 3	Ser_Thr_Tyr	C00000615	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00000615	3 / 1
P24298	Alanine aminotransferase 1	Enzyme	C00000615	0 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00002743	3 / 0
Q99489	D-aspartate oxidase	Enzyme	C00000207	0 / 0
P40225	Thrombopoietin	Unclassified protein	C00002644	1 / 1
Q8N1Q1	Carbonic anhydrase 13	Lyase	C00002664	0 / 0
P42345	Serine/threonine-protein kinase mTOR	Enzyme	C00002644	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00002644	1 / 0
O00255	Menin	Unclassified protein	C00000615	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000615	1 / 2
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00002644	0 / 0
P04406	Glyceraldehyde-3-phosphate dehydrogenase	Enzyme	C00002647	0 / 0
P07900	Heat shock protein HSP 90-alpha	Other cytosolic protein	C00000615	0 / 0
P08238	Heat shock protein HSP 90-beta	Other cytosolic protein	C00000615	0 / 0
P18507	Gamma-aminobutyric acid receptor subunit gamma-2	GABA-A gamma	C00002664	4 / 2
P47870	Gamma-aminobutyric acid receptor subunit beta-2	GABA-A beta	C00002664	0 / 0
P14867	Gamma-aminobutyric acid receptor subunit alpha-1	GABA-A alpha	C00002664	1 / 1
Q06124	Tyrosine-protein phosphatase non-receptor type 11	Tyr	C00000615	4 / 2

240 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00002644 C00002647 C00002665 C00002670 C00002689
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00000207 C00002682 C00002689 C00029961
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00002644 C00002647 C00002664 C00002689
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00002647 C00002689 C00002743
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00002644 C00002664 C00002689
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00002647 C00002689 C00002743
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00002647 C00002689 C00002743
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00000207 C00002644 C00002664
1312	COMT	catechol-O-methyltransferase (EC:2.1.1.6)	C00002644 C00002668 C00002670
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00000856 C00002644 C00002647
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00002644 C00002664 C00029961
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00000207 C00002664 C00002689
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00002682 C00002743 C00029961
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00002682 C00002743 C00029961
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00002682 C00002743 C00029961
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00002682 C00002743 C00029961
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00002647 C00002664 C00002689
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00002647 C00002743
581	BAX, BCL2L4	BCL2-associated X protein	C00002647 C00002665
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00002647 C00002665
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00002647 C00002670
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00002647 C00002665
7082	TJP1, ZO-1	tight junction protein 1	C00002664 C00002689
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00002647 C00002689
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00002647 C00002689
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00002647 C00002689
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00002647 C00002689
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00002664 C00002689
7299	TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3	tyrosinase (EC:1.14.18.1)	C00002743 C00029961
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00002647 C00002670
7037	TFRC, CD71, T9, TFR, TFR1, TR, TRFR, p90	transferrin receptor	C00002644 C00002664
5591	PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350	protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1)	C00002647 C00002664
6622	SNCA, NACP, PARK1, PARK4, PD1	synuclein, alpha (non A4 component of amyloid precursor)	C00002647 C00002670
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00002664 C00002743
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00002644 C00002664
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00002664 C00002743
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00002647 C00002670
6356	CCL11, SCYA11	chemokine (C-C motif) ligand 11	C00002644 C00002689
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00000207 C00002664
3145	HMBS, PBG-D, PBGD, PORC, UPS	hydroxymethylbilane synthase (EC:2.5.1.61)	C00002644 C00002664
3043	HBB, CD113t-C, beta-globin	hemoglobin, beta	C00002644 C00002664
6352	CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP	chemokine (C-C motif) ligand 5	C00002644 C00002689
2623	GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT	GATA binding protein 1 (globin transcription factor 1)	C00002644 C00002664
10440	TIMM17A, TIM17, TIM17A	translocase of inner mitochondrial membrane 17 homolog A (yeast)	C00002664
6348	CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3	chemokine (C-C motif) ligand 3	C00002644
3586	IL10, CSIF, GVHDS, IL-10, IL10A, TGIF	interleukin 10	C00002644
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00002644
212	ALAS2, ALAS-E, ALASE, ANH1, ASB, XLDPP, XLEPP, XLSA	aminolevulinate, delta-, synthase 2 (EC:2.3.1.37)	C00002644
3284	HSD3B2, HSD3B, HSDB, SDR11E2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (EC:1.1.1.145 5.3.3.1)	C00029961
338442	HCAR2, GPR109A, HCA2, HM74a, HM74b, NIACR1, PUMAG, Puma-g	hydroxycarboxylic acid receptor 2	C00029961
6799	SULT1A2, HAST4, P-PST, ST1A2, STP2, TSPST2	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 (EC:2.8.2.1)	C00002644
6818	SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1)	C00002644
6819	SULT1C2, ST1C1, ST1C2, SULT1C1, humSULTC2	sulfotransferase family, cytosolic, 1C, member 2 (EC:2.8.2.-)	C00002644
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00029961
3952	LEP, LEPD, OB, OBS	leptin	C00000856
183	AGT, ANHU, SERPINA8	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	C00002689
1386	ATF2, CRE-BP1, CREB2, HB16, TREB7	activating transcription factor 2 (EC:2.3.1.48)	C00002689
6362	CCL18, AMAC-1, AMAC1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	C00002689
6354	CCL7, FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7	chemokine (C-C motif) ligand 7	C00002689
948	CD36, BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3	CD36 molecule (thrombospondin receptor)	C00002689
1437	CSF2, GMCSF	colony stimulating factor 2 (granulocyte-macrophage)	C00002689
2919	CXCL1, FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	C00002689
3627	CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1	chemokine (C-X-C motif) ligand 10	C00002689
1536	CYBB, AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX	cytochrome b-245, beta polypeptide	C00002689
2033	EP300, KAT3B, RSTS2, p300	E1A binding protein p300 (EC:2.3.1.48)	C00002689
2335	FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF	fibronectin 1	C00002689
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00029961
27429	HTRA2, OMI, PARK13, PRSS25	HtrA serine peptidase 2 (EC:3.4.21.108)	C00002689
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00002689
3456	IFNB1, IFB, IFF, IFNB	interferon, beta 1, fibroblast	C00002689
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00029961
1558	CYP2C8, CPC8, CYPIIC8, MP-12/MP-20	cytochrome P450, family 2, subfamily C, polypeptide 8 (EC:1.14.14.1)	C00029961
3684	ITGAM, CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6	integrin, alpha M (complement component 3 receptor 3 subunit)	C00002689
3717	JAK2, JTK10, THCYT3	Janus kinase 2 (EC:2.7.10.2)	C00002689
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00002689
1557	CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19	cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00029961
1548	CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB	cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1)	C00029961
4282	MIF, GIF, GLIF, MMIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor) (EC:5.3.3.12 5.3.2.1)	C00002689
4322	MMP13, CLG3, MANDP1	matrix metallopeptidase 13 (collagenase 3) (EC:3.4.24.-)	C00002689
4481	MSR1, CD204, SCARA1, SR-A, SRA, phSR1, phSR2	macrophage scavenger receptor 1	C00002689
653361	NCF1, NCF1A, NOXO2, SH3PXD1A, p47phox	neutrophil cytosolic factor 1	C00002689
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00002689
4973	OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1	oxidized low density lipoprotein (lectin-like) receptor 1	C00002689
1586	CYP17A1, CPT7, CYP17, P450C17, S17AH	cytochrome P450, family 17, subfamily A, polypeptide 1 (EC:1.14.99.9 4.1.2.30)	C00029961
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00002689
6772	STAT1, CANDF7, ISGF-3, STAT91	signal transducer and activator of transcription 1, 91kDa	C00002689
2023	ENO1, ENO1L1, MPB1, NNE, PPH	enolase 1, (alpha) (EC:4.2.1.11)	C00002668
7040	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta	transforming growth factor, beta 1	C00018099
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00002689
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00002647
25	ABL1, ABL, JTK7, bcr/abl, c-ABL, p150, v-abl	c-abl oncogene 1, non-receptor tyrosine kinase (EC:2.7.10.2)	C00002647
4088	SMAD3, HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3	SMAD family member 3	C00018099
338	APOB, FLDB, LDLCQ4	apolipoprotein B	C00002647
472	ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1	ataxia telangiectasia mutated (EC:2.7.11.1)	C00002647
545	ATR, FCTCS, FRP1, MEC1, SCKL, SCKL1	ataxia telangiectasia and Rad3 related (EC:2.7.11.1)	C00002647
4087	SMAD2, JV18, JV18-1, MADH2, MADR2, hMAD-2, hSMAD2	SMAD family member 2	C00018099
6285	S100B, NEF, S100, S100-B, S100beta	S100 calcium binding protein B	C00018099
613	BCR, ALL, BCR1, CML, D22S11, D22S662, PHL	breakpoint cluster region (EC:2.7.11.1)	C00002647
177	AGER, RAGE	advanced glycosylation end product-specific receptor	C00018099
898	CCNE1, CCNE	cyclin E1	C00002647
998	CDC42, CDC42Hs, G25K	cell division cycle 42	C00002647
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00002647
1147	CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16	conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10)	C00002647
7852	CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM	chemokine (C-X-C motif) receptor 4	C00002647
6319	SCD, FADS5, MSTP008, SCD1, SCDOS	stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1)	C00002743
356	FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6	Fas ligand (TNF superfamily, member 6)	C00002647
2551	GABPA, E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A, RCH04A07	GA binding protein transcription factor, alpha subunit 60kDa	C00002647
2885	GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2	growth factor receptor-bound protein 2	C00002647
3551	IKBKB, IKK-beta, IKK2, IKKB, NFKBIKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)	C00002647
3949	LDLR, FH, FHC, LDLCQ2	low density lipoprotein receptor	C00002647
5604	MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1	mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)	C00002647
4255	MGMT	O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63)	C00002647
4313	MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24)	C00002647
4316	MMP7, MMP-7, MPSL1, PUMP-1	matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23)	C00002647
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00002647
4793	NFKBIB, IKBB, TRIP9	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	C00002647
5578	PRKCA, AAG6, PKC-alpha, PKCA, PRKACA	protein kinase C, alpha (EC:2.7.11.13)	C00002647
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00002743
5879	RAC1, Rac-1, TC-25, p21-Rac1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	C00002647
19412			C00002647
387	RHOA, ARH12, ARHA, RHO12, RHOH12	ras homolog family member A	C00002647
388	RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6	ras homolog family member B	C00002647
6195	RPS6KA1, HU-1, MAPKAPK1A, RSK, RSK1	ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1)	C00002647
9252	RPS6KA5, MSK1, MSPK1, RLPK	ribosomal protein S6 kinase, 90kDa, polypeptide 5 (EC:2.7.11.1)	C00002647
5742	PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00002743
23621	BACE1, ASP2, BACE, HSPC104	beta-site APP-cleaving enzyme 1 (EC:3.4.23.46)	C00002743
7224	TRPC5, TRP5	transient receptor potential cation channel, subfamily C, member 5	C00002647
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00002647
331	XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3	X-linked inhibitor of apoptosis	C00002647
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00002665
9518	GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB	growth differentiation factor 15	C00002665
2932	GSK3B	glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)	C00002665
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00002665
351	APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2	amyloid beta (A4) precursor protein	C00002670
847	CAT	catalase (EC:1.11.1.6)	C00002670
10965	ACOT2, CTE-IA, CTE1A, MTE1, PTE2, PTE2A, ZAP128	acyl-CoA thioesterase 2 (EC:3.1.2.2)	C00002664
174	AFP, FETA, HPAFP	alpha-fetoprotein	C00002664
213	ALB, PRO0883, PRO0903, PRO1341	albumin	C00002664
249	ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP	alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1)	C00002664
25805	BAMBI, NMA	BMP and activin membrane-bound inhibitor	C00002664
8553	BHLHE40, BHLHB2, DEC1, HLHB2, SHARP-2, STRA13, Stra14	basic helix-loop-helix family, member e40	C00002664
10904	BLCAP, BC10	bladder cancer associated protein	C00002664
813	CALU	calumenin	C00002664
890	CCNA2, CCN1, CCNA	cyclin A2	C00002664
9469	CHST3, C6ST, C6ST1, HSD	carbohydrate (chondroitin 6) sulfotransferase 3 (EC:2.8.2.17)	C00002664
9076	CLDN1, CLD1, ILVASC, SEMP1	claudin 1	C00002664
1277	COL1A1, OI4	collagen, type I, alpha 1	C00002664
1385	CREB1, CREB	cAMP responsive element binding protein 1	C00002664
100160140			C00002664
4051	CYP4F3, CPF3, CYP4F, LTB4H	cytochrome P450, family 4, subfamily F, polypeptide 3 (EC:1.14.13.30)	C00002664
26528	DAZAP1	DAZ associated protein 1	C00002664
55802	DCP1A, HSA275986, Nbla00360, SMAD4IP1, SMIF	decapping mRNA 1A	C00002664
1654	DDX3X, DBX, DDX14, DDX3, HLP2	DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked (EC:3.6.4.13)	C00002664
1843	DUSP1, CL100, HVH1, MKP-1, MKP1, PTPN10	dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48)	C00002664
22936	ELL2	elongation factor, RNA polymerase II, 2	C00002664
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00002664
2114	ETS2, ETS2IT1	v-ets avian erythroblastosis virus E26 oncogene homolog 2	C00002664
355	FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6	Fas cell surface death receptor	C00002664
26190	FBXW2, FBW2, Fwd2, Md6	F-box and WD repeat domain containing 2	C00002664
8061	FOSL1, FRA, FRA1, fra-1	FOS-like antigen 1	C00002664
2624	GATA2, DCML, MONOMAC, NFE1B	GATA binding protein 2	C00002664
9329	GTF3C4, KAT12, TFIII90, TFIIIC290, TFIIIC90, TFIIICDELTA	general transcription factor IIIC, polypeptide 4, 90kDa (EC:2.3.1.48)	C00002664
3014	H2AFX, H2A.X, H2A/X, H2AX	H2A histone family, member X	C00002664
26762	HAVCR1, HAVCR, HAVCR-1, KIM-1, KIM1, TIM, TIM-1, TIM1, TIMD-1, TIMD1	hepatitis A virus cellular receptor 1	C00002664
3280	HES1, HES-1, HHL, HRY, bHLHb39	hes family bHLH transcription factor 1	C00002664
3188	HNRNPH2, FTP3, HNRPH', HNRPH2, hnRNPH'	heterogeneous nuclear ribonucleoprotein H2 (H')	C00002664
3399	ID3, HEIR-1, bHLHb25	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	C00002664
3552	IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1	interleukin 1, alpha	C00002664
54556	ING3, Eaf4, ING2, MEAF4, p47ING3	inhibitor of growth family, member 3	C00002664
7071	KLF10, EGR-alpha, EGRA, TIEG, TIEG1	Kruppel-like factor 10	C00002664
1316	KLF6, BCD1, CBA1, COPEB, CPBP, GBF, PAC1, ST12, ZF9	Kruppel-like factor 6	C00002664
3840	KPNA4, IPOA3, QIP1, SRP3	karyopherin alpha 4 (importin alpha 3)	C00002664
4041	LRP5, BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2	low density lipoprotein receptor-related protein 5	C00002664
10905	MAN1A2, MAN1B	mannosidase, alpha, class 1A, member 2 (EC:3.2.1.113)	C00002664
4170	MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT	myeloid cell leukemia sequence 1 (BCL2-related)	C00002664
4247	MGAT2, CDG2A, CDGS2, GLCNACTII, GNT-II, GNT2	mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (EC:2.4.1.143)	C00002664
4353	MPO	myeloperoxidase (EC:1.11.2.2)	C00002664
740	MRPL49, C11orf4, L49mt, MRP-L49, NOF, NOF1	mitochondrial ribosomal protein L49	C00002664
4496	MT1H, MT-0, MT-1H, MT-IH, MT1	metallothionein 1H	C00002664
4501	MT1X, MT-1l, MT1	metallothionein 1X	C00002664
4778	NFE2, NF-E2, p45	nuclear factor, erythroid 2	C00002664
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00002664
4800	NFYA, CBF-A, CBF-B, HAP2, NF-YA	nuclear transcription factor Y, alpha	C00002664
8431	NR0B2, SHP, SHP1	nuclear receptor subfamily 0, group B, member 2	C00002664
57162	PELI1	pellino E3 ubiquitin protein ligase 1	C00002664
8864	PER2, FASPS, FASPS1	period circadian clock 2	C00002664
5293	PIK3CD, P110DELTA, PI3K, p110D	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta (EC:2.7.1.153)	C00002664
5292	PIM1, PIM	pim-1 oncogene (EC:2.7.11.1)	C00002664
9240	PNMA1, MA1	paraneoplastic Ma antigen 1	C00002664
5411	PNN, DRS, DRSP, SDK3, memA	pinin, desmosome associated protein	C00002664
10908	PNPLA6, NTE, NTEMND, SPG39, iPLA2delta, sws	patatin-like phospholipase domain containing 6 (EC:3.1.1.5)	C00002664
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00002664
8493	PPM1D, PP2C-DELTA, WIP1	protein phosphatase, Mg2+/Mn2+ dependent, 1D (EC:3.1.3.16)	C00002664
38175			C00002664
9367	RAB9A, RAB9	RAB9A, member RAS oncogene family	C00002664
29803	REPIN1, AP4, RIP60, ZNF464, Zfp464	replication initiator 1	C00002664
10670	RRAGA, FIP-1, FIP1, RAGA	Ras-related GTP binding A	C00002664
51282	SCAND1, RAZ1, SDP1	SCAN domain containing 1	C00002664
22928	SEPHS2, SPS2, SPS2b	selenophosphate synthetase 2 (EC:2.7.9.3)	C00002664
150094	SIK1, MSK, SIK, SNF1LK	salt-inducible kinase 1 (EC:2.7.11.1)	C00002664
23411	SIRT1, SIR2L1	sirtuin 1	C00002664
9990	SLC12A6, ACCPN, KCC3, KCC3A, KCC3B	solute carrier family 12 (potassium/chloride transporter), member 6	C00002664
6426	SRSF1, ASF, SF2, SF2p33, SFRS1, SRp30a	serine/arginine-rich splicing factor 1	C00002664
6430	SRSF5, HRS, SFRS5, SRP40	serine/arginine-rich splicing factor 5	C00002664
51188	SS18L2, KIAA-iso	synovial sarcoma translocation gene on chromosome 18-like 2	C00002664
6879	TAF7, TAF2F, TAFII55	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa	C00002664
23435	TARDBP, ALS10, TDP-43	TAR DNA binding protein	C00002664
10732	TCFL5, CHA, E2BP-1, Figlb, bHLHe82	transcription factor-like 5 (basic helix-loop-helix)	C00002664
7014	TERF2, TRBF2, TRF2	telomeric repeat binding factor 2	C00002664
7050	TGIF1, HPE4, TGIF	TGFB-induced factor homeobox 1	C00002664
6351	CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4	chemokine (C-C motif) ligand 4	C00002644
7128	TNFAIP3, A20, OTUD7C, TNFA1P2	tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12)	C00002664
27242	TNFRSF21, BM-018, CD358, DR6	tumor necrosis factor receptor superfamily, member 21	C00002664
10140	TOB1, APRO6, PIG49, TOB, TROB, TROB1	transducer of ERBB2, 1	C00002664
10221	TRIB1, C8FW, GIG-2, GIG2, SKIP1, TRB-1, TRB1	tribbles pseudokinase 1	C00002664
7286	TUFT1	tuftelin 1	C00002664
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00002743
7357	UGCG, GCS, GLCT1	UDP-glucose ceramide glucosyltransferase (EC:2.4.1.80)	C00002664
8876	VNN1, HDLCQ8, Tiff66	vanin 1 (EC:3.5.1.92)	C00002664
7444	VRK2	vaccinia related kinase 2 (EC:2.7.11.1)	C00002664
231	AKR1B1, ADR, ALDR1, ALR2, AR	aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21)	C00000207
57016	AKR1B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI	aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2)	C00000207
1645	AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB	aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112)	C00000207
8644	AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS	aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357)	C00000207
2235	FECH, EPP, FCE	ferrochelatase (EC:4.99.1.1)	C00000207
2512	FTL, NBIA3	ferritin, light polypeptide	C00000207
2539	G6PD, G6PD1	glucose-6-phosphate dehydrogenase (EC:1.1.1.49)	C00000207
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00000207
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00000207
2936	GSR	glutathione reductase (EC:1.8.1.7)	C00000207
2938	GSTA1, GST2, GSTA1-1, GTH1	glutathione S-transferase alpha 1 (EC:2.5.1.18)	C00000207
4097	MAFG, hMAF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G	C00000207
4199	ME1, HUMNDME, MES	malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40)	C00000207
4489	MT1A, MT1, MT1S, MTC	metallothionein 1A	C00000207
4502	MT2A, MT2	metallothionein 2A	C00000207
5226	PGD, 6PGD	phosphogluconate dehydrogenase (EC:1.1.1.44)	C00000207
22949	PTGR1, LTB4DH, PGR1, ZADH3	prostaglandin reductase 1 (EC:1.3.1.48 1.3.1.74)	C00000207
6566	SLC16A1, HHF7, MCT, MCT1	solute carrier family 16 (monocarboxylate transporter), member 1	C00000207
140809	SRXN1, C20orf139, Npn3, SRX, SRX1	sulfiredoxin 1 (EC:1.8.98.2)	C00000207
7295	TXN, TRDX, TRX, TRX1	thioredoxin	C00000207

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