| id | C00002664 | 
|---|---|
| Name | Phenol | 
| CAS RN | 108-95-2 | 
| Standard InChI | InChI=1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H | 
| Standard InChI (Main Layer) | InChI=1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H | 
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 6006 | 
| By standard InChI | CHEMBL14060 | 
|---|---|
| By standard InChI Main Layer | CHEMBL14060 | 
| By LinkDB | C00146 | 
|---|
| By CAS RN | D019800 | 
|---|
| class name | count | 
|---|---|
| rosids | 4 | 
| asterids | 3 | 
| Liliopsida | 1 | 
| eudicotyledons | 1 | 
| Viridiplantae | 1 | 
| family name | count | 
|---|---|
| Lamiaceae | 2 | 
| Meliaceae | 1 | 
| Ulvaceae | 1 | 
| Paeoniaceae | 1 | 
| Posidoniaceae | 1 | 
| Salicaceae | 1 | 
| Malvaceae | 1 | 
| Moraceae | 1 | 
| Rubiaceae | 1 | 
| accession | description | class description | compound | assay ID (# of activities) | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | CHEMBL14060 | CHEMBL1909136
                        (2) | 1 / 0 | 
| P21728 | D(1A) dopamine receptor | Dopamine receptor | CHEMBL14060 | CHEMBL1909139
                        (2) | 0 / 0 | 
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | CHEMBL14060 | CHEMBL1909131
                        (2) | 0 / 3 | 
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | CHEMBL14060 | CHEMBL1909190
                        (2) | 2 / 2 | 
| P08246 | Neutrophil elastase | S1A | CHEMBL14060 | CHEMBL1909195
                        (2) | 2 / 1 | 
| P33765 | Adenosine receptor A3 | Adenosine receptor | CHEMBL14060 | CHEMBL1909215
                        (2) | 0 / 0 | 
| Q16539 | Mitogen-activated protein kinase 14 | p38 | CHEMBL14060 | CHEMBL1909201
                        (2) | 0 / 0 | 
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | CHEMBL14060 | CHEMBL1909176
                        (2) | 0 / 0 | 
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | CHEMBL14060 | CHEMBL1074270
                        (1)
                        CHEMBL1217099
                        (1) CHEMBL1227478 (1) CHEMBL2341301 (1) | 0 / 0 | 
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | CHEMBL14060 | CHEMBL1074269
                        (1)
                        CHEMBL1217098
                        (1) CHEMBL1227477 (1) CHEMBL2341302 (1) | 0 / 0 | 
| P43166 | Carbonic anhydrase 7 | Lyase | CHEMBL14060 | CHEMBL1074272
                        (1)
                        CHEMBL1217101
                        (1) CHEMBL1227480 (1) CHEMBL2341299 (1) | 0 / 0 | 
| P29466 | Caspase-1 | C14 | CHEMBL14060 | CHEMBL1909193
                        (2) | 0 / 0 | 
| P17252 | Protein kinase C alpha type | Alpha | CHEMBL14060 | CHEMBL1909198
                        (2) | 0 / 0 | 
| P27361 | Mitogen-activated protein kinase 3 | Erk | CHEMBL14060 | CHEMBL1909199
                        (2) | 0 / 0 | 
| P14780 | Matrix metalloproteinase-9 | M10A | CHEMBL14060 | CHEMBL1909197
                        (2) | 2 / 2 | 
| Q8N1Q1 | Carbonic anhydrase 13 | Lyase | CHEMBL14060 | CHEMBL1227626
                        (1)
                        CHEMBL2341296
                        (1) | 0 / 0 | 
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | CHEMBL14060 | CHEMBL1794371
                        (1) | 0 / 0 | 
| P00918 | Carbonic anhydrase 2 | Lyase | CHEMBL14060 | CHEMBL1074266
                        (1)
                        CHEMBL1217095
                        (1) CHEMBL1227474 (1) CHEMBL1670882 (1) CHEMBL1695108 (1) CHEMBL1909123 (2) CHEMBL2328242 (1) CHEMBL2328250 (1) CHEMBL2341304 (1) | 1 / 2 | 
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | CHEMBL14060 | CHEMBL1909092
                        (2) | 0 / 1 | 
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | CHEMBL14060 | CHEMBL1909169
                        (2) | 1 / 1 | 
| P25021 | Histamine H2 receptor | Histamine receptor | CHEMBL14060 | CHEMBL1909157
                        (2) | 0 / 0 | 
| P35367 | Histamine H1 receptor | Histamine receptor | CHEMBL14060 | CHEMBL1909156
                        (2) | 0 / 0 | 
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | CHEMBL14060 | CHEMBL1909143
                        (2) | 1 / 0 | 
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | CHEMBL14060 | CHEMBL1909174
                        (2) | 0 / 0 | 
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | CHEMBL14060 | CHEMBL1909090
                        (2) | 0 / 0 | 
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | CHEMBL14060 | CHEMBL1909093
                        (2) | 0 / 0 | 
| P04066 | Tissue alpha-L-fucosidase | Enzyme | CHEMBL14060 | CHEMBL875424
                        (1)
                        CHEMBL649593
                        (1) | 1 / 2 | 
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | CHEMBL14060 | CHEMBL1909127
                        (2) | 0 / 0 | 
| P06241 | Tyrosine-protein kinase Fyn | Src | CHEMBL14060 | CHEMBL1909204
                        (2) | 0 / 0 | 
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | CHEMBL14060 | CHEMBL1909202
                        (2) | 0 / 0 | 
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | CHEMBL14060 | CHEMBL1909135
                        (2) | 0 / 1 | 
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | CHEMBL14060 | CHEMBL1909203
                        (2) | 1 / 11 | 
| P14416 | D(2) dopamine receptor | Dopamine receptor | CHEMBL14060 | CHEMBL1909140
                        (2) | 2 / 0 | 
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | CHEMBL14060 | CHEMBL1909130
                        (2) | 0 / 0 | 
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | CHEMBL14060 | CHEMBL1909120
                        (2) | 0 / 0 | 
| P41145 | Kappa-type opioid receptor | Opioid receptor | CHEMBL14060 | CHEMBL1909181
                        (2) | 0 / 0 | 
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | CHEMBL14060 | CHEMBL1909164
                        (2) | 0 / 0 | 
| P29274 | Adenosine receptor A2a | Adenosine receptor | CHEMBL14060 | CHEMBL1909214
                        (2) | 0 / 0 | 
| P23280 | Carbonic anhydrase 6 | Lyase | CHEMBL14060 | CHEMBL1074271
                        (1)
                        CHEMBL1217100
                        (1) CHEMBL1227479 (1) CHEMBL2341300 (1) | 0 / 0 | 
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | CHEMBL14060 | CHEMBL1909175
                        (2) | 0 / 0 | 
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | CHEMBL14060 | CHEMBL1909096
                        (2) | 1 / 1 | 
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | CHEMBL14060 | CHEMBL1909118
                        (2) | 0 / 0 | 
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | CHEMBL14060 | CHEMBL1909166
                        (2) | 1 / 0 | 
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | CHEMBL14060 | CHEMBL1074276
                        (1)
                        CHEMBL1217105
                        (1) CHEMBL1227627 (1) CHEMBL2341295 (1) | 0 / 0 | 
| O43570 | Carbonic anhydrase 12 | Lyase | CHEMBL14060 | CHEMBL1074274
                        (1)
                        CHEMBL1217103
                        (1) CHEMBL1227625 (1) CHEMBL1670884 (1) CHEMBL2328241 (1) CHEMBL2341297 (1) | 1 / 2 | 
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | CHEMBL14060 | CHEMBL1909133
                        (2) | 0 / 0 | 
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | CHEMBL14060 | CHEMBL1909158
                        (2) | 0 / 0 | 
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | CHEMBL14060 | CHEMBL1909088
                        (2) | 0 / 0 | 
| P21917 | D(4) dopamine receptor | Dopamine receptor | CHEMBL14060 | CHEMBL1909142
                        (2) | 0 / 0 | 
| P30988 | Calcitonin receptor | Calcitonin receptor | CHEMBL14060 | CHEMBL1909101
                        (2) | 0 / 0 | 
| P35462 | D(3) dopamine receptor | Dopamine receptor | CHEMBL14060 | CHEMBL1909141
                        (2) | 1 / 0 | 
| P41143 | Delta-type opioid receptor | Opioid receptor | CHEMBL14060 | CHEMBL1909180
                        (2) | 0 / 0 | 
| Q92731 | Estrogen receptor beta | NR3A2 | CHEMBL14060 | CHEMBL1909146
                        (2) | 0 / 1 | 
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | CHEMBL14060 | CHEMBL1909104
                        (2) | 0 / 0 | 
| P25101 | Endothelin-1 receptor | Endothelin receptor | CHEMBL14060 | CHEMBL1909144
                        (2) | 0 / 0 | 
| P30411 | B2 bradykinin receptor | Bradykinin receptor | CHEMBL14060 | CHEMBL1909100
                        (2) | 0 / 0 | 
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | CHEMBL14060 | CHEMBL1909167
                        (2) | 1 / 0 | 
| P00915 | Carbonic anhydrase 1 | Lyase | CHEMBL14060 | CHEMBL1074265
                        (1)
                        CHEMBL1217094
                        (1) CHEMBL1227473 (1) CHEMBL1670881 (1) CHEMBL1695107 (1) CHEMBL2328243 (1) CHEMBL2341306 (1) | 0 / 0 | 
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | CHEMBL14060 | CHEMBL1909129
                        (2) | 0 / 0 | 
| P08311 | Cathepsin G | S1A | CHEMBL14060 | CHEMBL1909194
                        (2) | 0 / 0 | 
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | CHEMBL14060 | CHEMBL1909110
                        (2) | 1 / 0 | 
| P03956 | Interstitial collagenase | M10A | CHEMBL14060 | CHEMBL1909196
                        (2) | 0 / 1 | 
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | CHEMBL14060 | CHEMBL1909119
                        (2) | 0 / 0 | 
| P04150 | Glucocorticoid receptor | NR3C1 | CHEMBL14060 | CHEMBL1909150
                        (2) | 0 / 1 | 
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | CHEMBL14060 | CHEMBL1909171
                        (2) | 2 / 0 | 
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | CHEMBL14060 | CHEMBL1909170
                        (2) | 0 / 0 | 
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | CHEMBL14060 | CHEMBL1909122
                        (2) | 0 / 0 | 
| P31645 | Sodium-dependent serotonin transporter | Serotonin | CHEMBL14060 | CHEMBL1909109
                        (2) | 2 / 0 | 
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | CHEMBL14060 | CHEMBL1794510
                        (1) | 5 / 3 | 
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | CHEMBL14060 | CHEMBL1909205
                        (2) | 5 / 10 | 
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | CHEMBL14060 | CHEMBL1909172
                        (2) | 1 / 0 | 
| P21452 | Substance-K receptor | Neurokinin receptor | CHEMBL14060 | CHEMBL1909114
                        (2) | 0 / 0 | 
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | CHEMBL14060 | CHEMBL1909125
                        (2) | 0 / 0 | 
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | CHEMBL14060 | CHEMBL1909126
                        (2) | 3 / 0 | 
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | CHEMBL14060 | CHEMBL1909108
                        (2) | 0 / 0 | 
| P06280 | Alpha-galactosidase A | Enzyme | CHEMBL14060 | CHEMBL1614217
                        (1) | 1 / 1 | 
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | CHEMBL14060 | CHEMBL1909124
                        (2) | 1 / 0 | 
| P28482 | Mitogen-activated protein kinase 1 | Erk | CHEMBL14060 | CHEMBL1909200
                        (2) | 0 / 0 | 
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | CHEMBL14060 | CHEMBL1909207
                        (2) | 2 / 1 | 
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | CHEMBL14060 | CHEMBL1909132
                        (2) | 0 / 0 | 
| Q16790 | Carbonic anhydrase 9 | Lyase | CHEMBL14060 | CHEMBL1074273
                        (1)
                        CHEMBL1217102
                        (1) CHEMBL1228226 (1) CHEMBL1670883 (1) CHEMBL2328240 (1) CHEMBL2341298 (1) | 0 / 1 | 
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | CHEMBL14060 | CHEMBL1909186
                        (2) | 0 / 0 | 
| P03372 | Estrogen receptor | NR3A1 | CHEMBL14060 | CHEMBL1909145
                        (2) | 1 / 1 | 
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | CHEMBL14060 | CHEMBL1909091
                        (2) | 1 / 0 | 
| P22303 | Acetylcholinesterase | Hydrolase | CHEMBL14060 | CHEMBL1909212
                        (2) | 1 / 0 | 
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | CHEMBL14060 | CHEMBL1909211
                        (2) | 0 / 0 | 
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | CHEMBL14060 | CHEMBL1909105
                        (2) | 0 / 0 | 
| P35372 | Mu-type opioid receptor | Opioid receptor | CHEMBL14060 | CHEMBL1909182
                        (2) | 0 / 0 | 
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | CHEMBL14060 | CHEMBL1909173
                        (2) | 0 / 0 | 
| P25103 | Substance-P receptor | Neurokinin receptor | CHEMBL14060 | CHEMBL1909113
                        (2) | 0 / 0 | 
| P25105 | Platelet-activating factor receptor | PAF receptor | CHEMBL14060 | CHEMBL1909187
                        (2) | 0 / 0 | 
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | CHEMBL14060 | CHEMBL1909168
                        (2) | 0 / 0 | 
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | CHEMBL14060 | CHEMBL1909134
                        (2) | 1 / 1 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | CHEMBL14060 | CHEMBL1909138
                        (2) | 0 / 1 | 
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | CHEMBL14060 | CHEMBL1909137
                        (2) | 0 / 0 | 
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | CHEMBL14060 | CHEMBL1908083
                        (2) | 0 / 0 | 
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | CHEMBL14060 | CHEMBL2114890
                        (2) | 0 / 0 | 
| P10275 | Androgen receptor | NR3C4 | CHEMBL14060 | CHEMBL1794321
                        (2) | 3 / 4 | 
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | CHEMBL14060 | CHEMBL1909094
                        (2) | 1 / 1 | 
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | CHEMBL14060 | CHEMBL1909087
                        (2) | 0 / 0 | 
| P30542 | Adenosine receptor A1 | Adenosine receptor | CHEMBL14060 | CHEMBL1909213
                        (2) | 0 / 0 | 
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | CHEMBL14060 | CHEMBL1909089
                        (2) | 0 / 0 | 
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | CHEMBL14060 | CHEMBL1909116
                        (2) | 1 / 1 | 
| P07451 | Carbonic anhydrase 3 | Lyase | CHEMBL14060 | CHEMBL1074267
                        (1)
                        CHEMBL1217096
                        (1) CHEMBL1227475 (1) CHEMBL2341305 (1) | 0 / 0 | 
| P06239 | Tyrosine-protein kinase Lck | Src | CHEMBL14060 | CHEMBL1909206
                        (2) | 0 / 1 | 
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | CHEMBL14060 | CHEMBL1909128
                        (2) | 0 / 0 | 
| P22748 | Carbonic anhydrase 4 | Lyase | CHEMBL14060 | CHEMBL1074268
                        (1)
                        CHEMBL1217097
                        (1) CHEMBL1227476 (1) CHEMBL2341303 (1) | 1 / 1 | 
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | CHEMBL14060 | CHEMBL1614364
                        (1) | 1 / 1 | 
| P18507 | Gamma-aminobutyric acid receptor subunit gamma-2 | GABA-A gamma | CHEMBL14060 | CHEMBL678910
                        (1)
                        CHEMBL678911
                        (1) | 4 / 2 | 
| P47870 | Gamma-aminobutyric acid receptor subunit beta-2 | GABA-A beta | CHEMBL14060 | CHEMBL678910
                        (1)
                        CHEMBL678911
                        (1) | 0 / 0 | 
| P14867 | Gamma-aminobutyric acid receptor subunit alpha-1 | GABA-A alpha | CHEMBL14060 | CHEMBL678910
                        (1)
                        CHEMBL678911
                        (1) | 1 / 1 | 
| compound | gene | gene name | gene description | interaction | interaction type | form | reference pmid | 
|---|---|---|---|---|---|---|---|
| D019800 | 10965 | ACOT2 CTE-IA CTE1A MTE1 PTE2 PTE2A ZAP128 | acyl-CoA thioesterase 2 (EC:3.1.2.2) | Phenol results in decreased expression of ACOT2 mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 174 | AFP FETA HPAFP | alpha-fetoprotein | Phenol results in increased expression of AFP protein | increases expression | protein | 16966304 | 
| D019800 | 213 | ALB PRO0883 PRO0903 PRO1341 | albumin | Phenol binds to ALB protein | affects binding | protein | 11334365 | 
| D019800 | 249 | ALPL AP-TNAP APTNAP HOPS TNAP TNSALP | alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1) | Phenol results in increased expression of ALPL mRNA | increases expression | mRNA | 22083529 | 
| D019800 | 25805 | BAMBI NMA | BMP and activin membrane-bound inhibitor | Phenol results in increased expression of BAMBI mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 8553 | BHLHE40 BHLHB2 DEC1 HLHB2 SHARP-2 STRA13 Stra14 | basic helix-loop-helix family, member e40 | Phenol results in increased expression of BHLHE40 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 10904 | BLCAP BC10 | bladder cancer associated protein | Phenol results in decreased expression of BLCAP mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 813 | CALU | calumenin | Phenol results in decreased expression of CALU mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 6347 | CCL2 GDCF-2 HC11 HSMCR30 MCAF MCP-1 MCP1 SCYA2 SMC-CF | chemokine (C-C motif) ligand 2 | Phenol results in increased expression of CCL2 mRNA | increases expression | mRNA | 21907259 | 
| D019800 | 890 | CCNA2 CCN1 CCNA | cyclin A2 | Phenol results in decreased expression of CCNA2 protein | decreases expression | protein | 19293009 | 
| D019800 | 9469 | CHST3 C6ST C6ST1 HSD | carbohydrate (chondroitin 6) sulfotransferase 3 (EC:2.8.2.17) | Phenol results in increased expression of CHST3 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 9076 | CLDN1 CLD1 ILVASC SEMP1 | claudin 1 | Phenol affects the localization of CLDN1 protein | affects localization | protein | 19679145 | 
| D019800 | 1277 | COL1A1 OI4 | collagen, type I, alpha 1 | Phenol results in increased expression of COL1A1 mRNA | increases expression | mRNA | 22083529 | 
| D019800 | 1385 | CREB1 CREB | cAMP responsive element binding protein 1 | Phenol results in increased expression of CREB1 mRNA | increases expression | mRNA | 20385217 | 
| D019800 | 100160140 | Phenol results in decreased expression of CROP mRNA | decreases expression | mRNA | 17547211 | ||
| D019800 | 1543 | CYP1A1 AHH AHRR CP11 CYP1 P1-450 P450-C P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | CYP1A1 protein affects the susceptibility to Phenol | affects response to substance | protein | 8242868 | 
| D019800 | 1544 | CYP1A2 CP12 P3-450 P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) | CYP1A2 protein affects the susceptibility to Phenol | affects response to substance | protein | 8242868 | 
| D019800 | 1571 | CYP2E1 CPE1 CYP2E P450-J P450C2E | cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | [CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of Phenol | affects chemical synthesis / affects metabolic processing | protein | 15051535 | 
| D019800 | 4051 | CYP4F3 CPF3 CYP4F LTB4H | cytochrome P450, family 4, subfamily F, polypeptide 3 (EC:1.14.13.30) | Phenol results in increased expression of CYP4F3 mRNA | increases expression | mRNA | 19029204 20036648 | 
| D019800 | 4051 | CYP4F3 CPF3 CYP4F LTB4H | cytochrome P450, family 4, subfamily F, polypeptide 3 (EC:1.14.13.30) | Phenol results in increased expression of CYP4F3 protein | increases expression | protein | 19029204 20036648 | 
| D019800 | 26528 | DAZAP1 | DAZ associated protein 1 | Phenol results in increased expression of DAZAP1 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 55802 | DCP1A HSA275986 Nbla00360 SMAD4IP1 SMIF | decapping mRNA 1A | Phenol results in increased expression of DCP1A mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 1654 | DDX3X DBX DDX14 DDX3 HLP2 | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked (EC:3.6.4.13) | Phenol results in decreased expression of DDX3X mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 1843 | DUSP1 CL100 HVH1 MKP-1 MKP1 PTPN10 | dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48) | Phenol results in increased expression of DUSP1 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 22936 | ELL2 | elongation factor, RNA polymerase II, 2 | Phenol results in increased expression of ELL2 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 2099 | ESR1 ER ESR ESRA ESTRR Era NR3A1 | estrogen receptor 1 | Phenol results in increased expression of ESR1 mRNA | increases expression | mRNA | 22083529 | 
| D019800 | 2114 | ETS2 ETS2IT1 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | Phenol results in increased expression of ETS2 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 355 | FAS ALPS1A APO-1 APT1 CD95 FAS1 FASTM TNFRSF6 | Fas cell surface death receptor | Phenol results in increased expression of FAS mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 26190 | FBXW2 FBW2 Fwd2 Md6 | F-box and WD repeat domain containing 2 | Phenol results in decreased expression of FBXW2 mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 8061 | FOSL1 FRA FRA1 fra-1 | FOS-like antigen 1 | Phenol results in increased expression of FOSL1 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 2623 | GATA1 ERYF1 GATA-1 GF-1 GF1 NF-E1 NFE1 XLANP XLTDA XLTT | GATA binding protein 1 (globin transcription factor 1) | Phenol inhibits the reaction [Hemin results in increased expression of GATA1 mRNA] | decreases reaction / increases expression | mRNA | 21414390 | 
| D019800 | 2624 | GATA2 DCML MONOMAC NFE1B | GATA binding protein 2 | Phenol promotes the reaction [Hemin results in decreased expression of GATA2 mRNA] | decreases expression / increases reaction | mRNA | 21414390 | 
| D019800 | 2624 | GATA2 DCML MONOMAC NFE1B | GATA binding protein 2 | Phenol results in decreased expression of GATA2 mRNA | decreases expression | mRNA | 21414390 | 
| D019800 | 9329 | GTF3C4 KAT12 TFIII90 TFIIIC290 TFIIIC90 TFIIICDELTA | general transcription factor IIIC, polypeptide 4, 90kDa (EC:2.3.1.48) | Phenol results in increased expression of GTF3C4 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 3014 | H2AFX H2A.X H2A/X H2AX | H2A histone family, member X | Phenol affects the localization of H2AFX protein modified form | affects localization | protein | 20096274 | 
| D019800 | 26762 | HAVCR1 HAVCR HAVCR-1 KIM-1 KIM1 TIM TIM-1 TIM1 TIMD-1 TIMD1 | hepatitis A virus cellular receptor 1 | Phenol results in increased expression of HAVCR1 mRNA | increases expression | mRNA | 21907259 | 
| D019800 | 3043 | HBB CD113t-C beta-globin | hemoglobin, beta | Phenol inhibits the reaction [Hemin results in increased expression of HBB mRNA] | decreases reaction / increases expression | mRNA | 21414390 | 
| D019800 | 3280 | HES1 HES-1 HHL HRY bHLHb39 | hes family bHLH transcription factor 1 | Phenol results in increased expression of HES1 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 3145 | HMBS PBG-D PBGD PORC UPS | hydroxymethylbilane synthase (EC:2.5.1.61) | Phenol inhibits the reaction [Hemin results in increased expression of HMBS mRNA] | decreases reaction / increases expression | mRNA | 21414390 | 
| D019800 | 3162 | HMOX1 HMOX1D HO-1 HSP32 bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) | Phenol results in increased expression of HMOX1 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 3188 | HNRNPH2 FTP3 HNRPH' HNRPH2 hnRNPH' | heterogeneous nuclear ribonucleoprotein H2 (H') | Phenol results in decreased expression of HNRNPH2 mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 3399 | ID3 HEIR-1 bHLHb25 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | Phenol results in increased expression of ID3 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 3552 | IL1A IL-1A IL1 IL1-ALPHA IL1F1 | interleukin 1, alpha | IL1A protein affects the reaction [Phenol results in increased expression of IL8 protein] | affects reaction / increases expression | protein | 8006454 | 
| D019800 | 3552 | IL1A IL-1A IL1 IL1-ALPHA IL1F1 | interleukin 1, alpha | Phenol results in increased expression of IL1A mRNA | increases expression | mRNA | 8006454 | 
| D019800 | 3552 | IL1A IL-1A IL1 IL1-ALPHA IL1F1 | interleukin 1, alpha | Phenol results in increased expression of IL1A protein | increases expression | protein | 8006454 | 
| D019800 | 3552 | IL1A IL-1A IL1 IL1-ALPHA IL1F1 | interleukin 1, alpha | Phenol results in increased secretion of IL1A protein | increases secretion | protein | 16522979 | 
| D019800 | 3553 | IL1B IL-1 IL1-BETA IL1F2 | interleukin 1, beta | Phenol results in increased expression of IL1B mRNA | increases expression | mRNA | 8006454 | 
| D019800 | 3576 | IL8 CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 | interleukin 8 | IL1A protein affects the reaction [Phenol results in increased expression of IL8 protein] | affects reaction / increases expression | protein | 8006454 | 
| D019800 | 3576 | IL8 CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 | interleukin 8 | Phenol results in increased expression of IL8 mRNA | increases expression | mRNA | 8006454 | 
| D019800 | 3576 | IL8 CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 | interleukin 8 | Phenol results in increased expression of IL8 protein | increases expression | protein | 8006454 | 
| D019800 | 3576 | IL8 CXCL8 GCP-1 GCP1 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1 | interleukin 8 | TNF protein affects the reaction [Phenol results in increased expression of IL8 protein] | affects reaction / increases expression | protein | 8006454 | 
| D019800 | 54556 | ING3 Eaf4 ING2 MEAF4 p47ING3 | inhibitor of growth family, member 3 | Phenol results in increased expression of ING3 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 7071 | KLF10 EGR-alpha EGRA TIEG TIEG1 | Kruppel-like factor 10 | Phenol results in increased expression of KLF10 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 1316 | KLF6 BCD1 CBA1 COPEB CPBP GBF PAC1 ST12 ZF9 | Kruppel-like factor 6 | Phenol results in increased expression of KLF6 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 3840 | KPNA4 IPOA3 QIP1 SRP3 | karyopherin alpha 4 (importin alpha 3) | Phenol results in increased expression of KPNA4 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 4041 | LRP5 BMND1 EVR1 EVR4 HBM LR3 LRP7 OPPG OPS OPTA1 VBCH2 | low density lipoprotein receptor-related protein 5 | Phenol results in increased expression of LRP5 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 10905 | MAN1A2 MAN1B | mannosidase, alpha, class 1A, member 2 (EC:3.2.1.113) | Phenol results in decreased expression of MAN1A2 mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 4170 | MCL1 BCL2L3 EAT MCL1-ES MCL1L MCL1S Mcl-1 TM bcl2-L-3 mcl1/EAT | myeloid cell leukemia sequence 1 (BCL2-related) | Phenol results in decreased expression of MCL1 mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 4247 | MGAT2 CDG2A CDGS2 GLCNACTII GNT-II GNT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (EC:2.4.1.143) | Phenol results in decreased expression of MGAT2 mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 4353 | MPO | myeloperoxidase (EC:1.11.2.2) | MPO protein results in increased hydroxylation of Phenol | increases hydroxylation | protein | 1666626 | 
| D019800 | 4353 | MPO | myeloperoxidase (EC:1.11.2.2) | [MPO protein results in increased hydroxylation of Phenol] which results in increased chemical synthesis of hydroquinone | increases chemical synthesis / increases hydroxylation | protein | 1666626 | 
| D019800 | 740 | MRPL49 C11orf4 L49mt MRP-L49 NOF NOF1 | mitochondrial ribosomal protein L49 | Phenol results in decreased expression of MRPL49 mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 4496 | MT1H MT-0 MT-1H MT-IH MT1 | metallothionein 1H | Phenol results in decreased expression of MT1H mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 4501 | MT1X MT-1l MT1 | metallothionein 1X | Phenol results in decreased expression of MT1X mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 4609 | MYC MRTL MYCC bHLHe39 c-Myc | v-myc avian myelocytomatosis viral oncogene homolog | Phenol results in increased expression of MYC mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 4778 | NFE2 NF-E2 p45 | nuclear factor, erythroid 2 | Phenol inhibits the reaction [Hemin results in increased expression of NFE2 mRNA] | decreases reaction / increases expression | mRNA | 21414390 | 
| D019800 | 4790 | NFKB1 EBP-1 KBF1 NF-kB1 NF-kappa-B NF-kappaB NFKB-p105 NFKB-p50 NFkappaB p105 p50 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | Phenol results in increased expression of NFKB1 mRNA | increases expression | mRNA | 20385217 | 
| D019800 | 4800 | NFYA CBF-A CBF-B HAP2 NF-YA | nuclear transcription factor Y, alpha | Phenol results in increased expression of NFYA mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 1728 | NQO1 DHQU DIA4 DTD NMOR1 NMORI QR1 | NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) | Phenol results in increased activity of NQO1 protein | increases activity | protein | 9029048 | 
| D019800 | 1728 | NQO1 DHQU DIA4 DTD NMOR1 NMORI QR1 | NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) | Phenol results in increased expression of NQO1 mRNA | increases expression | mRNA | 9029048 | 
| D019800 | 8431 | NR0B2 SHP SHP1 | nuclear receptor subfamily 0, group B, member 2 | Phenol results in decreased expression of NR0B2 mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 57162 | PELI1 | pellino E3 ubiquitin protein ligase 1 | Phenol results in increased expression of PELI1 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 8864 | PER2 FASPS FASPS1 | period circadian clock 2 | Phenol results in increased expression of PER2 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 5293 | PIK3CD P110DELTA PI3K p110D | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta (EC:2.7.1.153) | Phenol results in increased expression of PIK3CD mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 5292 | PIM1 PIM | pim-1 oncogene (EC:2.7.11.1) | Phenol results in increased expression of PIM1 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 9240 | PNMA1 MA1 | paraneoplastic Ma antigen 1 | Phenol results in decreased expression of PNMA1 mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 5411 | PNN DRS DRSP SDK3 memA | pinin, desmosome associated protein | Phenol results in decreased expression of PNN mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 10908 | PNPLA6 NTE NTEMND SPG39 iPLA2delta sws | patatin-like phospholipase domain containing 6 (EC:3.1.1.5) | [PNPLA6 protein results in increased hydrolysis of phenyl valerate] which results in increased chemical synthesis of Phenol | increases chemical synthesis / increases hydrolysis | protein | 20603202 | 
| D019800 | 5468 | PPARG CIMT1 GLM1 NR1C3 PPARG1 PPARG2 PPARgamma | peroxisome proliferator-activated receptor gamma | Phenol results in increased expression of PPARG mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 8493 | PPM1D PP2C-DELTA WIP1 | protein phosphatase, Mg2+/Mn2+ dependent, 1D (EC:3.1.3.16) | Phenol results in increased expression of PPM1D mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 5591 | PRKDC DNA-PKcs DNAPK DNPK1 HYRC HYRC1 XRCC7 p350 | protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1) | Phenol affects the localization of PRKDC protein | affects localization | protein | 20096274 | 
| D019800 | 5591 | PRKDC DNA-PKcs DNAPK DNPK1 HYRC HYRC1 XRCC7 p350 | protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1) | Phenol results in increased expression of PRKDC | increases expression | 20036648 | |
| D019800 | 5591 | PRKDC DNA-PKcs DNAPK DNPK1 HYRC HYRC1 XRCC7 p350 | protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1) | Phenol results in increased expression of PRKDC mRNA | increases expression | mRNA | 20096274 | 
| D019800 | 5591 | PRKDC DNA-PKcs DNAPK DNPK1 HYRC HYRC1 XRCC7 p350 | protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1) | Phenol results in increased expression of PRKDC protein | increases expression | protein | 20096274 | 
| D019800 | 38175 | Phenol results in increased expression of PSA protein | increases expression | protein | 16966304 | ||
| D019800 | 9367 | RAB9A RAB9 | RAB9A, member RAS oncogene family | Phenol results in decreased expression of RAB9A mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 29803 | REPIN1 AP4 RIP60 ZNF464 Zfp464 | replication initiator 1 | Phenol results in decreased expression of REPIN1 mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 10670 | RRAGA FIP-1 FIP1 RAGA | Ras-related GTP binding A | Phenol results in decreased expression of RRAGA mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 51282 | SCAND1 RAZ1 SDP1 | SCAN domain containing 1 | Phenol results in decreased expression of SCAND1 mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 22928 | SEPHS2 SPS2 SPS2b | selenophosphate synthetase 2 (EC:2.7.9.3) | Phenol results in decreased expression of SEPHS2 mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 150094 | SIK1 MSK SIK SNF1LK | salt-inducible kinase 1 (EC:2.7.11.1) | Phenol results in increased expression of SIK1 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 23411 | SIRT1 SIR2L1 | sirtuin 1 | Phenol results in increased expression of SIRT1 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 9990 | SLC12A6 ACCPN KCC3 KCC3A KCC3B | solute carrier family 12 (potassium/chloride transporter), member 6 | Phenol results in increased expression of SLC12A6 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 6426 | SRSF1 ASF SF2 SF2p33 SFRS1 SRp30a | serine/arginine-rich splicing factor 1 | Phenol results in decreased expression of SRSF1 mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 6430 | SRSF5 HRS SFRS5 SRP40 | serine/arginine-rich splicing factor 5 | Phenol results in decreased expression of SRSF5 mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 51188 | SS18L2 KIAA-iso | synovial sarcoma translocation gene on chromosome 18-like 2 | Phenol results in decreased expression of SS18L2 mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 6879 | TAF7 TAF2F TAFII55 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa | Phenol results in decreased expression of TAF7 mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 23435 | TARDBP ALS10 TDP-43 | TAR DNA binding protein | Phenol results in decreased expression of TARDBP mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 10732 | TCFL5 CHA E2BP-1 Figlb bHLHe82 | transcription factor-like 5 (basic helix-loop-helix) | Phenol results in increased expression of TCFL5 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 7014 | TERF2 TRBF2 TRF2 | telomeric repeat binding factor 2 | Phenol results in increased expression of TERF2 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 7037 | TFRC CD71 T9 TFR TFR1 TR TRFR p90 | transferrin receptor | Phenol promotes the reaction [Hemin results in decreased expression of TFRC mRNA] | decreases expression / increases reaction | mRNA | 21414390 | 
| D019800 | 7037 | TFRC CD71 T9 TFR TFR1 TR TRFR p90 | transferrin receptor | Phenol results in decreased expression of TFRC protein | decreases expression | protein | 21414390 | 
| D019800 | 7050 | TGIF1 HPE4 TGIF | TGFB-induced factor homeobox 1 | Phenol results in increased expression of TGIF1 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 10440 | TIMM17A TIM17 TIM17A | translocase of inner mitochondrial membrane 17 homolog A (yeast) | Phenol results in decreased expression of TIMM17A mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 7082 | TJP1 ZO-1 | tight junction protein 1 | Phenol affects the localization of TJP1 protein | affects localization | protein | 19679145 | 
| D019800 | 7124 | TNF DIF TNF-alpha TNFA TNFSF2 | tumor necrosis factor | Phenol results in increased expression of TNF mRNA | increases expression | mRNA | 8006454 20385217 | 
| D019800 | 7124 | TNF DIF TNF-alpha TNFA TNFSF2 | tumor necrosis factor | Phenol results in increased expression of TNF protein | increases expression | protein | 8006454 | 
| D019800 | 7124 | TNF DIF TNF-alpha TNFA TNFSF2 | tumor necrosis factor | Phenol results in increased secretion of TNF protein | increases secretion | protein | 16522979 | 
| D019800 | 7124 | TNF DIF TNF-alpha TNFA TNFSF2 | tumor necrosis factor | TNF protein affects the reaction [Phenol results in increased expression of IL8 protein] | affects reaction / increases expression | protein | 8006454 | 
| D019800 | 7128 | TNFAIP3 A20 OTUD7C TNFA1P2 | tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12) | Phenol results in increased expression of TNFAIP3 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 27242 | TNFRSF21 BM-018 CD358 DR6 | tumor necrosis factor receptor superfamily, member 21 | Phenol results in increased expression of TNFRSF21 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 10140 | TOB1 APRO6 PIG49 TOB TROB TROB1 | transducer of ERBB2, 1 | Phenol results in decreased expression of TOB1 mRNA | decreases expression | mRNA | 17547211 | 
| D019800 | 10221 | TRIB1 C8FW GIG-2 GIG2 SKIP1 TRB-1 TRB1 | tribbles pseudokinase 1 | Phenol results in increased expression of TRIB1 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 7286 | TUFT1 | tuftelin 1 | Phenol results in increased expression of TUFT1 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 7296 | TXNRD1 GRIM-12 TR TR1 TRXR1 TXNR | thioredoxin reductase 1 (EC:1.8.1.9) | Phenol results in increased expression of TXNRD1 mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 7357 | UGCG GCS GLCT1 | UDP-glucose ceramide glucosyltransferase (EC:2.4.1.80) | Phenol results in increased expression of UGCG mRNA | increases expression | mRNA | 17547211 | 
| D019800 | 8876 | VNN1 HDLCQ8 Tiff66 | vanin 1 (EC:3.5.1.92) | Phenol results in increased expression of VNN1 mRNA | increases expression | mRNA | 21907259 | 
| D019800 | 7444 | VRK2 | vaccinia related kinase 2 (EC:2.7.11.1) | Phenol results in increased expression of VRK2 mRNA | increases expression | mRNA | 17547211 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism | P20309 | 
| #103780 | Alcohol dependence | P08172 P14416 P31645 | 
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 | Q99720 | 
| #300068 | Androgen insensitivity syndrome; ais | P10275 | 
| #312300 | Androgen insensitivity, partial; pais | P10275 | 
| #602025 | Body mass index quantitative trait locus 9; bmiq9 | P41968 | 
| %606641 | Body mass index; bmi | P37231 | 
| #300615 | Brunner syndrome | P21397 | 
| #609338 | Carotid intimal medial thickness 1 | P37231 | 
| #162800 | Cyclic neutropenia | P08246 | 
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 | P51681 | 
| #607208 | Dravet syndrome | P18507 | 
| #609535 | Drug metabolism, poor, cyp2c19-related | P33261 | 
| #608902 | Drug metabolism, poor, cyp2d6-related | P10635 | 
| #607681 | Epilepsy, childhood absence, susceptibility to, 2; eca2 | P18507 | 
| #611136 | Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 | P14867 | 
| #615363 | Estrogen resistance; estrr | P03372 | 
| #301500 | Fabry disease | P06280 | 
| #230000 | Fucosidosis | P04066 | 
| #613659 | Gastric cancer | P04626 | 
| #137215 | Gastric cancer, hereditary diffuse; hdgc | P04626 | 
| #604233 | Generalized epilepsy with febrile seizures plus, type 1; gefsp1 | P18507 | 
| #611277 | Generalized epilepsy with febrile seizures plus, type 3; gefsp3 | P18507 | 
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd | P24557 | 
| #137800 | Glioma susceptibility 1; glm1 | P04626 P37231 | 
| #609423 | Human immunodeficiency virus type 1, susceptibility to | P41597 P51681 | 
| #143860 | Hyperchlorhidrosis, isolated | O43570 | 
| #603932 | Intervertebral disc disease; idd | P14780 | 
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 | P37231 | 
| #613688 | Long qt syndrome 2; lqt2 | Q12809 | 
| #211980 | Lung cancer | P00533 P04626 | 
| #608516 | Major depressive disorder; mdd | P08172 | 
| %300852 | Mental retardation, x-linked 88; mrx88 | P50052 | 
| #613073 | Metaphyseal anadysplasia 2; mandp2 | P14780 | 
| #126200 | Multiple sclerosis, susceptibility to; ms | P08575 | 
| #159900 | Myoclonic dystonia | P14416 | 
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 | P08246 | 
| #601665 | Obesity | P32245 P37231 | 
| #164230 | Obsessive-compulsive disorder; ocd | P31645 | 
| #604715 | Orthostatic intolerance | P23975 | 
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 | P00918 | 
| #167000 | Ovarian cancer | P04626 | 
| #613135 | Parkinsonism-dystonia, infantile; pkdys | Q01959 | 
| #607276 | Resting heart rate, variation in | P08588 | 
| #600852 | Retinitis pigmentosa 17; rp17 | P22748 | 
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive | P08575 | 
| #609620 | Short qt syndrome 1; sqt1 | Q12809 | 
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 | P10275 | 
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 | Q9NUW8 | 
| #190300 | Tremor, hereditary essential, 1; etm1 | P35462 | 
| #610379 | West nile virus, susceptibility to | P51681 | 
| #112100 | Yt blood group antigen | P22303 | 
| KEGG | disease name | UniProt | 
|---|---|---|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) | O43570
                            (related) | 
| H00021 | Renal cell carcinoma | O43570
                            (marker) Q16790 (marker) | 
| H00016 | Oral cancer | P00533
                            (related) P00533 (marker) | 
| H00017 | Esophageal cancer | P00533
                            (related) P35354 (related) | 
| H00018 | Gastric cancer | P00533
                            (related) P04626 (related) | 
| H00022 | Bladder cancer | P00533
                            (related) P04626 (related) | 
| H00028 | Choriocarcinoma | P00533
                            (related) P03956 (related) P04626 (related) | 
| H00030 | Cervical cancer | P00533
                            (related) P04626 (related) | 
| H00042 | Glioma | P00533
                            (related) P00533 (marker) | 
| H00055 | Laryngeal cancer | P00533
                            (related) P00533 (marker) | 
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) | P00918
                            (related) | 
| H00436 | Osteopetrosis | P00918
                            (related) | 
| H00026 | Endometrial Cancer | P03372
                            (marker) P04626 (related) Q92731 (marker) | 
| H00141 | Fucosidosis | P04066
                            (related) | 
| H00422 | Glycoproteinoses | P04066
                            (related) | 
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) | P04150
                            (related) | 
| H00019 | Pancreatic cancer | P04626
                            (related) | 
| H00027 | Ovarian cancer | P04626
                            (related) | 
| H00031 | Breast cancer | P04626
                            (related) P04626 (marker) | 
| H00046 | Cholangiocarcinoma | P04626
                            (related) P35354 (related) | 
| H00093 | Combined immunodeficiencies (CIDs) | P06239
                            (related) | 
| H00125 | Fabry disease | P06280
                            (related) | 
| H00079 | Asthma | P07550
                            (related) | 
| H00100 | Neutropenic disorders | P08246
                            (related) | 
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) | P08575
                            (related) | 
| H00036 | Osteosarcoma | P08684
                            (marker) | 
| H00024 | Prostate cancer | P10275
                            (related) | 
| H00062 | Spinal and bulbar muscular atrophy (SBMA) | P10275
                            (related) | 
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) | P10275
                            (related) | 
| H00609 | 46,XY disorders of sex development (Other) | P10275
                            (related) | 
| H01205 | Coumarin resistance | P11712
                            (related) | 
| H00025 | Penile cancer | P14780
                            (related) P35354 (related) | 
| H00479 | Metaphyseal dysplasias | P14780
                            (related) | 
| H00808 | Idiopathic generalized epilepsies (IGEs) | P14867
                            (related) P18507 (related) | 
| H00783 | Febrile seizures | P18507
                            (related) | 
| H00548 | Brunner syndrome | P21397
                            (related) | 
| H00527 | Retinitis pigmentosa (RP) | P22748
                            (related) | 
| H01031 | Orthostatic intolerance (OI) | P23975
                            (related) | 
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) | P24557
                            (related) | 
| H01171 | Poor drug metabolism (PM) | P33261
                            (related) | 
| H00032 | Thyroid cancer | P37231
                            (related) | 
| H00409 | Type II diabetes mellitus | P37231
                            (related) | 
| H00420 | Familial partial lipodystrophy (FPL) | P37231
                            (related) | 
| H00480 | Non-syndromic X-linked mental retardation | P50052
                            (related) | 
| H00720 | Long QT syndrome | Q12809
                            (related) | 
| H00725 | Short QT syndrome | Q12809
                            (related) | 
| H00063 | Spinocerebellar ataxia (SCA) | Q9NUW8
                            (related) | 
| MeSH disease | OMIM | compound | disease name | evidence type | reference pmid | 
|---|---|---|---|---|---|
| D058186 | D019800 | Acute Kidney Injury | marker/mechanism | 20409856 | |
| D001855 | D019800 | Bone Marrow Diseases | marker/mechanism | 2551665 | |
| D001859 | D019800 | Bone Neoplasms | therapeutic | 10556009 | |
| D001913 | D019800 | Bowen's Disease | therapeutic | 19293009 | |
| D003128 | D019800 | COMA | marker/mechanism | 10465250 | |
| D003556 | D019800 | Cystitis | therapeutic | 1054198 | |
| D017449 | D019800 | Dermatitis, Allergic Contact | marker/mechanism | 12121405 | |
| D003877 | D019800 | Dermatitis, Contact | marker/mechanism | 17922553 | |
| D004382 | D019800 | Duodenitis | marker/mechanism | 10465250 | |
| D004487 | D019800 | Edema | marker/mechanism | 8006454 | |
| D005756 | D019800 | Gastritis | marker/mechanism | 10465250 | |
| D006417 | D019800 | Hematuria | therapeutic | 1054198 | |
| D006470 | D019800 | Hemorrhage | therapeutic | 1054198 | |
| D006973 | D019800 | Hypertension | marker/mechanism | 20409856 | |
| D007035 | D019800 | Hypothermia | marker/mechanism | 17329239 | |
| D055623 | D019800 | Keratosis, Actinic | therapeutic | 19293009 | |
| D048629 | D019800 | Micronuclei, Chromosome-Defective | marker/mechanism | 2924392 | |
| D009784 | D019800 | Occupational Diseases | marker/mechanism | 9930093 | |
| D010146 | D019800 | Pain | therapeutic | 17610455 | |
| D020734 | D019800 | Parkinsonian Disorders | marker/mechanism | 10465250 | |
| D010392 | D019800 | Pemphigus | marker/mechanism | 16522979 17163923 | |
| D010523 | D019800 | Peripheral Nervous System Diseases | marker/mechanism | 6318389 | |
| D010864 | D019800 | Pilonidal Sinus | therapeutic | 15622588 19655223 | |
| D011041 | D019800 | Poisoning | marker/mechanism | 8291054 8818868 8825745 9930093 | |
| D012131 | D019800 | Respiratory Insufficiency | marker/mechanism | 10465250 | |
| D013088 | D019800 | Spermatocele | therapeutic | 18646496 | |
| D006848 | D019800 | Testicular Hydrocele | therapeutic | 18646496 | |
| D014202 | D019800 | Tremor | marker/mechanism | 7639639 | |
| D014277 | D019800 | Trigeminal Neuralgia | therapeutic | 10223447 16527771 | |
| D014860 | D019800 | Warts | therapeutic | 19122958 |