Melia azadirach

• Index
• Plant Species
• Metabolite list (21)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Melia azadirach
Genus	Melia
Family	Meliaceae
Kingdom	Plantae

---

NCBI taxonomy

Entry

Linked NCBI taxonomy name	Melia azedarach
Linked NCBI taxonomy ID	155640
Linked level	species

Family

Family in NCBI taxonomy	Meliaceae
ID	43707

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (21)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00046069	Kulinone	CHEMBL464491				No. 119	No. 51
C00020065	alpha-Cadinol / (-)-alpha-Cadinol	CHEMBL486795				No. 205	No. 38
C00020150	(-)-Torreyol / delta-Cadinol	CHEMBL486795				No. 205	No. 38
C00035686	Melianone	CHEMBL486466				No. 264	No. 51
C00000816	beta-Pinene	CHEMBL501351	C010789			No. 476	No. 35
C00000805	alpha-Pinene	CHEMBL442565	C005451	3 / 3 / 2	0 / 1	No. 476	No. 35
C00043791	Ohchinolal	CHEMBL501420				No. 591	No. 51
C00000823	Limonene	CHEMBL15799 CHEMBL449062	C008281	7 / 21 / 48	6 / 6	No. 848	No. 35
C00003047	Linalool / (R)-linalool / (R)-(-)-3,7-Dimethyl-1,6-octadien-3-ol	CHEMBL25306 CHEMBL235672	C018584	6 / 8 / 2	35 / 4	No. 958	No. 34
C00048262	1-p-Menthene					No. 1052	No. 35
C00007636	delta-Cadinene	CHEMBL445759				No. 1524	No. 39
C00002645	p-Cresol / 4-Methylphenol	CHEMBL16645	C032538	8 / 4 / 4	10 / 4	No. 1546
C00030878	o-Cresol	CHEMBL46931	C034047	4 / 9 / 3	1 / 4	No. 1546
C00035128	m-Cresol / m-Oxytoluene	CHEMBL298312	C042041	6 / 4 / 1	1 / 3	No. 1546
C00000844	Citronellol	CHEMBL395827 CHEMBL1907993 CHEMBL1907995	C007078	7 / 5 / 4	1 / 1	No. 1948	No. 34
C00003040	p-Cymene	CHEMBL442915	C007210			No. 2172	No. 35
C00002654	Guaiacol / o-Guaiacol	CHEMBL13766	D006139	15 / 18 / 47	3 / 1	No. 2352
C00003029	Camphene	CHEMBL506889 CHEMBL510535	C019286			No. 2460	No. 35
C00033189	Melianin B	CHEMBL446959				No. 2887
C00000861	Terpinolene	CHEMBL454697	C027009		1 / 0	No. 3725
C00002664	Phenol	CHEMBL14060	D019800	111 / 52 / 47	101 / 30	No. 6006

Human Protein / Gene in interactions

137 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00000823 C00000844 C00002645 C00002654 C00002664 C00030878 C00035128	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00000823 C00003047 C00035128	3 / 1
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00000805 C00002645 C00002654	0 / 0
P10275	Androgen receptor	NR3C4	C00002645 C00002654 C00002664	3 / 4
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00000823 C00002664 C00035128	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000823 C00000844 C00002664	0 / 3
P22303	Acetylcholinesterase	Hydrolase	C00002645 C00002664 C00035128	1 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00000823 C00002654	7 / 37
Q9Y4X1	UDP-glucuronosyltransferase 2A1	Enzyme	C00000844 C00003047	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00000844 C00003047	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00000805 C00002664	0 / 0
P03956	Interstitial collagenase	M10A	C00002654 C00002664	0 / 1
P00915	Carbonic anhydrase 1	Lyase	C00002654 C00002664	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00000844 C00002645	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00002654 C00002664	1 / 2
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00000844 C00003047	5 / 1
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00002645 C00002664	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00000805 C00002654	3 / 2
P14780	Matrix metalloproteinase-9	M10A	C00002654 C00002664	2 / 2
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00002664	0 / 0
Q8N1Q1	Carbonic anhydrase 13	Lyase	C00002664	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00000823	11 / 10
P27361	Mitogen-activated protein kinase 3	Erk	C00002664	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00002664	0 / 0
P29466	Caspase-1	C14	C00002664	0 / 0
P22894	Neutrophil collagenase	M10A	C00002654	0 / 0
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00002664	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00002664	1 / 1
P25021	Histamine H2 receptor	Histamine receptor	C00002664	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00002664	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00002664	1 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00002664	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00002664	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00002664	0 / 0
P04066	Tissue alpha-L-fucosidase	Enzyme	C00002664	1 / 2
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00002664	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00002664	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00002664	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002664	0 / 1
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00002664	1 / 8
P14416	D(2) dopamine receptor	Dopamine receptor	C00002664	2 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00002664	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00002664	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00002664	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00002664	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00002664	0 / 0
P23280	Carbonic anhydrase 6	Lyase	C00002664	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00002664	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00002664	1 / 1
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00002664	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00002664	1 / 0
Q9ULX7	Carbonic anhydrase 14	Lyase	C00002664	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00000844	0 / 0
O43570	Carbonic anhydrase 12	Lyase	C00002664	1 / 2
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00002664	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00035128	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00030878	2 / 0
P50225	Sulfotransferase 1A1	Enzyme	C00002645	0 / 0
P43166	Carbonic anhydrase 7	Lyase	C00002664	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00002664	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00002664	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00002664	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00002664	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00002664	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00002664	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00002664	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00002664	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00002664	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00002664	0 / 0
P10145	Interleukin-8	Secreted protein	C00002645	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00002664	1 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00002664	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00002664	0 / 0
P08311	Cathepsin G	S1A	C00002664	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00002664	1 / 0
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00002664	0 / 0
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00002664	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00030878	7 / 3
P83916	Chromobox protein homolog 1	Unclassified protein	C00003047	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00002664	0 / 1
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00002664	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00002664	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00002664	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00002664	2 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00002664	5 / 3
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00002664	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00002664	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00002664	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00002664	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00002664	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00002664	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00002664	1 / 1
Q96RI1	Bile acid receptor	NR1H4	C00030878	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00002664	1 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00002664	0 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00002664	2 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002664	0 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00002664	0 / 1
P08253	72 kDa type IV collagenase	M10A	C00002654	1 / 3
Q16539	Mitogen-activated protein kinase 14	p38	C00002664	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00002654	0 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00002664	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00000823	0 / 0
P03372	Estrogen receptor	NR3A1	C00002664	1 / 1
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00002664	1 / 0
P08246	Neutrophil elastase	S1A	C00002664	2 / 1
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00002664	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00002664	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00002664	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00002664	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00002664	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00002664	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00002664	0 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00002664	2 / 2
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002664	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002664	0 / 1
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00002664	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00002664	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00002654	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002664	1 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00003047	3 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00002664	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00002664	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00002664	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00002664	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00002664	1 / 1
P07451	Carbonic anhydrase 3	Lyase	C00002664	0 / 0
P06239	Tyrosine-protein kinase Lck	Src	C00002664	0 / 1
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00002664	0 / 0
P08254	Stromelysin-1	M10A	C00002654	1 / 0
P22748	Carbonic anhydrase 4	Lyase	C00002664	1 / 1
Q9UBT6	DNA polymerase kappa	Enzyme	C00035128	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00002654	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002664	1 / 1
P18507	Gamma-aminobutyric acid receptor subunit gamma-2	GABA-A gamma	C00002664	4 / 2
P47870	Gamma-aminobutyric acid receptor subunit beta-2	GABA-A beta	C00002664	0 / 0
P14867	Gamma-aminobutyric acid receptor subunit alpha-1	GABA-A alpha	C00002664	1 / 1

144 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
213	ALB, PRO0883, PRO0903, PRO1341	albumin	C00002645 C00002654 C00002664 C00030878
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000823 C00002664 C00003047
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000823 C00003047
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00000823 C00002664
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00002645 C00002664
4852	NPY, PYY4	neuropeptide Y	C00000823 C00003047
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00002645 C00002664
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00002645 C00002664
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00000861 C00003047
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00002645 C00002664
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00002664 C00003047
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00002664 C00003047
5292	PIM1, PIM	pim-1 oncogene (EC:2.7.11.1)	C00002664
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00003047
1028	CDKN1C, BWCR, BWS, KIP2, WBS, p57, p57Kip2	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	C00003047
1030	CDKN2B, CDK4I, INK4B, MTS2, P15, TP15, p15INK4b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	C00003047
1447	CSN2, CASB	casein beta	C00003047
1509	CTSD, CLN10, CPSD	cathepsin D (EC:3.4.23.5)	C00003047
1906	EDN1, ET1, HDLCQ7, PPET1	endothelin 1	C00003047
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00003047
2335	FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF	fibronectin 1	C00003047
1647	GADD45A, DDIT1, GADD45	growth arrest and DNA-damage-inducible, alpha	C00003047
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00003047
3156	HMGCR, LDLCQ3	3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34)	C00003047
3297	HSF1, HSTF1	heat shock transcription factor 1	C00003047
3320	HSP90AA1, EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2	heat shock protein 90kDa alpha (cytosolic), class A member 1	C00003047
3308	HSPA4, APG-2, HS24/P52, HSPH2, RY, hsp70, hsp70RY	heat shock 70kDa protein 4	C00003047
3316	HSPB2, HSP27, Hs.78846, LOH11CR1K, MKBP	heat shock 27kDa protein 2	C00003047
3398	ID2, GIG8, ID2A, ID2H, bHLHb26	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	C00003047
3638	INSIG1, CL-6, CL6	insulin induced gene 1	C00003047
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00003047
8850	KAT2B, CAF, P, P/CAF, PCAF	K(lysine) acetyltransferase 2B (EC:2.3.1.48)	C00003047
4193	MDM2, ACTFS, HDMX, hdm2	MDM2 oncogene, E3 ubiquitin protein ligase	C00003047
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00003047
329	BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1	baculoviral IAP repeat containing 2	C00003047
100124292			C00003047
7295	TXN, TRDX, TRX, TRX1	thioredoxin	C00003047
7471	WNT1, BMND16, INT1, OI15	wingless-type MMTV integration site family, member 1	C00003047
26118	WSB1, SWIP1, WSB-1	WD repeat and SOCS box containing 1	C00003047
1386	ATF2, CRE-BP1, CREB2, HB16, TREB7	activating transcription factor 2 (EC:2.3.1.48)	C00003047
6376	CX3CL1, ABCD-3, C3Xkine, CXC3, CXC3C, NTN, NTT, SCYD1, fractalkine, neurotactin	chemokine (C-X3-C motif) ligand 1	C00002645
1646	AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8	aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357)	C00003047
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00002645
3265	HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1	Harvey rat sarcoma viral oncogene homolog	C00000823
50848	F11R, CD321, JAM, JAM1, JAMA, JCAM, KAT, PAM-1	F11 receptor	C00002645
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00002645
7442	TRPV1, VR1	transient receptor potential cation channel, subfamily V, member 1	C00000844
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000823
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00002645
6329	SCN4A, HOKPP2, HYKPP, HYPP, NAC1A, Na(V)1.4, Nav1.4, SkM1	sodium channel, voltage-gated, type IV, alpha subunit	C00035128
759	CA1, CA-I, CAB, Car1	carbonic anhydrase I (EC:4.2.1.1)	C00002654
760	CA2, CA-II, CAC, CAII, Car2	carbonic anhydrase II (EC:4.2.1.1)	C00002654
10965	ACOT2, CTE-IA, CTE1A, MTE1, PTE2, PTE2A, ZAP128	acyl-CoA thioesterase 2 (EC:3.1.2.2)	C00002664
174	AFP, FETA, HPAFP	alpha-fetoprotein	C00002664
249	ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP	alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1)	C00002664
25805	BAMBI, NMA	BMP and activin membrane-bound inhibitor	C00002664
8553	BHLHE40, BHLHB2, DEC1, HLHB2, SHARP-2, STRA13, Stra14	basic helix-loop-helix family, member e40	C00002664
10904	BLCAP, BC10	bladder cancer associated protein	C00002664
813	CALU	calumenin	C00002664
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00002664
890	CCNA2, CCN1, CCNA	cyclin A2	C00002664
9469	CHST3, C6ST, C6ST1, HSD	carbohydrate (chondroitin 6) sulfotransferase 3 (EC:2.8.2.17)	C00002664
9076	CLDN1, CLD1, ILVASC, SEMP1	claudin 1	C00002664
1277	COL1A1, OI4	collagen, type I, alpha 1	C00002664
1385	CREB1, CREB	cAMP responsive element binding protein 1	C00002664
100160140			C00002664
4051	CYP4F3, CPF3, CYP4F, LTB4H	cytochrome P450, family 4, subfamily F, polypeptide 3 (EC:1.14.13.30)	C00002664
26528	DAZAP1	DAZ associated protein 1	C00002664
55802	DCP1A, HSA275986, Nbla00360, SMAD4IP1, SMIF	decapping mRNA 1A	C00002664
1654	DDX3X, DBX, DDX14, DDX3, HLP2	DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked (EC:3.6.4.13)	C00002664
1843	DUSP1, CL100, HVH1, MKP-1, MKP1, PTPN10	dual specificity phosphatase 1 (EC:3.1.3.16 3.1.3.48)	C00002664
22936	ELL2	elongation factor, RNA polymerase II, 2	C00002664
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00002664
2114	ETS2, ETS2IT1	v-ets avian erythroblastosis virus E26 oncogene homolog 2	C00002664
355	FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6	Fas cell surface death receptor	C00002664
26190	FBXW2, FBW2, Fwd2, Md6	F-box and WD repeat domain containing 2	C00002664
8061	FOSL1, FRA, FRA1, fra-1	FOS-like antigen 1	C00002664
2623	GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT	GATA binding protein 1 (globin transcription factor 1)	C00002664
2624	GATA2, DCML, MONOMAC, NFE1B	GATA binding protein 2	C00002664
9329	GTF3C4, KAT12, TFIII90, TFIIIC290, TFIIIC90, TFIIICDELTA	general transcription factor IIIC, polypeptide 4, 90kDa (EC:2.3.1.48)	C00002664
3014	H2AFX, H2A.X, H2A/X, H2AX	H2A histone family, member X	C00002664
26762	HAVCR1, HAVCR, HAVCR-1, KIM-1, KIM1, TIM, TIM-1, TIM1, TIMD-1, TIMD1	hepatitis A virus cellular receptor 1	C00002664
3043	HBB, CD113t-C, beta-globin	hemoglobin, beta	C00002664
3280	HES1, HES-1, HHL, HRY, bHLHb39	hes family bHLH transcription factor 1	C00002664
3145	HMBS, PBG-D, PBGD, PORC, UPS	hydroxymethylbilane synthase (EC:2.5.1.61)	C00002664
3188	HNRNPH2, FTP3, HNRPH', HNRPH2, hnRNPH'	heterogeneous nuclear ribonucleoprotein H2 (H')	C00002664
3399	ID3, HEIR-1, bHLHb25	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	C00002664
3552	IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1	interleukin 1, alpha	C00002664
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00002664
54556	ING3, Eaf4, ING2, MEAF4, p47ING3	inhibitor of growth family, member 3	C00002664
7071	KLF10, EGR-alpha, EGRA, TIEG, TIEG1	Kruppel-like factor 10	C00002664
1316	KLF6, BCD1, CBA1, COPEB, CPBP, GBF, PAC1, ST12, ZF9	Kruppel-like factor 6	C00002664
3840	KPNA4, IPOA3, QIP1, SRP3	karyopherin alpha 4 (importin alpha 3)	C00002664
4041	LRP5, BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2	low density lipoprotein receptor-related protein 5	C00002664
10905	MAN1A2, MAN1B	mannosidase, alpha, class 1A, member 2 (EC:3.2.1.113)	C00002664
4170	MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT	myeloid cell leukemia sequence 1 (BCL2-related)	C00002664
4247	MGAT2, CDG2A, CDGS2, GLCNACTII, GNT-II, GNT2	mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (EC:2.4.1.143)	C00002664
4353	MPO	myeloperoxidase (EC:1.11.2.2)	C00002664
740	MRPL49, C11orf4, L49mt, MRP-L49, NOF, NOF1	mitochondrial ribosomal protein L49	C00002664
4496	MT1H, MT-0, MT-1H, MT-IH, MT1	metallothionein 1H	C00002664
4501	MT1X, MT-1l, MT1	metallothionein 1X	C00002664
4778	NFE2, NF-E2, p45	nuclear factor, erythroid 2	C00002664
4800	NFYA, CBF-A, CBF-B, HAP2, NF-YA	nuclear transcription factor Y, alpha	C00002664
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00002664
8431	NR0B2, SHP, SHP1	nuclear receptor subfamily 0, group B, member 2	C00002664
57162	PELI1	pellino E3 ubiquitin protein ligase 1	C00002664
8864	PER2, FASPS, FASPS1	period circadian clock 2	C00002664
5293	PIK3CD, P110DELTA, PI3K, p110D	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta (EC:2.7.1.153)	C00002664
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00003047
9240	PNMA1, MA1	paraneoplastic Ma antigen 1	C00002664
5411	PNN, DRS, DRSP, SDK3, memA	pinin, desmosome associated protein	C00002664
10908	PNPLA6, NTE, NTEMND, SPG39, iPLA2delta, sws	patatin-like phospholipase domain containing 6 (EC:3.1.1.5)	C00002664
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00002664
8493	PPM1D, PP2C-DELTA, WIP1	protein phosphatase, Mg2+/Mn2+ dependent, 1D (EC:3.1.3.16)	C00002664
5591	PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350	protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1)	C00002664
38175			C00002664
9367	RAB9A, RAB9	RAB9A, member RAS oncogene family	C00002664
29803	REPIN1, AP4, RIP60, ZNF464, Zfp464	replication initiator 1	C00002664
10670	RRAGA, FIP-1, FIP1, RAGA	Ras-related GTP binding A	C00002664
51282	SCAND1, RAZ1, SDP1	SCAN domain containing 1	C00002664
22928	SEPHS2, SPS2, SPS2b	selenophosphate synthetase 2 (EC:2.7.9.3)	C00002664
150094	SIK1, MSK, SIK, SNF1LK	salt-inducible kinase 1 (EC:2.7.11.1)	C00002664
23411	SIRT1, SIR2L1	sirtuin 1	C00002664
9990	SLC12A6, ACCPN, KCC3, KCC3A, KCC3B	solute carrier family 12 (potassium/chloride transporter), member 6	C00002664
6426	SRSF1, ASF, SF2, SF2p33, SFRS1, SRp30a	serine/arginine-rich splicing factor 1	C00002664
6430	SRSF5, HRS, SFRS5, SRP40	serine/arginine-rich splicing factor 5	C00002664
51188	SS18L2, KIAA-iso	synovial sarcoma translocation gene on chromosome 18-like 2	C00002664
6879	TAF7, TAF2F, TAFII55	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa	C00002664
23435	TARDBP, ALS10, TDP-43	TAR DNA binding protein	C00002664
10732	TCFL5, CHA, E2BP-1, Figlb, bHLHe82	transcription factor-like 5 (basic helix-loop-helix)	C00002664
7014	TERF2, TRBF2, TRF2	telomeric repeat binding factor 2	C00002664
7037	TFRC, CD71, T9, TFR, TFR1, TR, TRFR, p90	transferrin receptor	C00002664
7050	TGIF1, HPE4, TGIF	TGFB-induced factor homeobox 1	C00002664
10440	TIMM17A, TIM17, TIM17A	translocase of inner mitochondrial membrane 17 homolog A (yeast)	C00002664
7082	TJP1, ZO-1	tight junction protein 1	C00002664
7128	TNFAIP3, A20, OTUD7C, TNFA1P2	tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12)	C00002664
27242	TNFRSF21, BM-018, CD358, DR6	tumor necrosis factor receptor superfamily, member 21	C00002664
10140	TOB1, APRO6, PIG49, TOB, TROB, TROB1	transducer of ERBB2, 1	C00002664
10221	TRIB1, C8FW, GIG-2, GIG2, SKIP1, TRB-1, TRB1	tribbles pseudokinase 1	C00002664
7286	TUFT1	tuftelin 1	C00002664
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00002664
7357	UGCG, GCS, GLCT1	UDP-glucose ceramide glucosyltransferase (EC:2.4.1.80)	C00002664
8876	VNN1, HDLCQ8, Tiff66	vanin 1 (EC:3.5.1.92)	C00002664
7444	VRK2	vaccinia related kinase 2 (EC:2.7.11.1)	C00002664

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions