KCF-S cluster No. 1546 (7 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (7)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
asterids	6
rosids	6
Spermatophyta	3
eudicotyledons	2
Euphyllophyta	1

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Cumulative family count

class name	count
Aspergillaceae	6
Meliaceae	3
Ericaceae	2
Brassicaceae	2
Solanaceae	2
Pteridaceae	1
Saxifragaceae	1
Podocarpaceae	1
Apiaceae	1
Didymellaceae	1
Pinaceae	1
Amaranthaceae	1
Asteraceae	1
Moraceae	1
Hypocreaceae	1
Cupressaceae	1

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (7)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002645	p-Cresol / 4-Methylphenol	CHEMBL16645	C032538	8 / 4 / 4	10 / 4
C00002649	Gentisyl alcohol	CHEMBL448800	C004771
C00002660	4-Methylcatechol	CHEMBL158766	C018599		1 / 2
C00002661	Orcinol	CHEMBL110059	C005282	1 / 4 / 2
C00023720	Toluquinol	CHEMBL450917	C062397
C00030878	o-Cresol	CHEMBL46931	C034047	4 / 9 / 3	1 / 4
C00035128	m-Cresol / m-Oxytoluene	CHEMBL298312	C042041	6 / 4 / 1	1 / 3

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002645 C00030878 C00035128	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00002645 C00035128	1 / 0
P14679	Tyrosinase	Oxidoreductase	C00002661	4 / 2
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00030878	2 / 0
P50225	Sulfotransferase 1A1	Enzyme	C00002645	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00002645	0 / 0
P10145	Interleukin-8	Secreted protein	C00002645	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00030878	7 / 3
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00035128	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00030878	0 / 0
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00002645	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00035128	3 / 1
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00002645	0 / 0
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00035128	0 / 0
P10275	Androgen receptor	NR3C4	C00002645	3 / 4
Q9UBT6	DNA polymerase kappa	Enzyme	C00035128	0 / 0

12 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
213	ALB, PRO0883, PRO0903, PRO1341	albumin	C00002645 C00030878
50848	F11R, CD321, JAM, JAM1, JAMA, JCAM, KAT, PAM-1	F11 receptor	C00002645
6376	CX3CL1, ABCD-3, C3Xkine, CXC3, CXC3C, NTN, NTT, SCYD1, fractalkine, neurotactin	chemokine (C-X3-C motif) ligand 1	C00002645
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00002645
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00002645
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00002645
1312	COMT	catechol-O-methyltransferase (EC:2.1.1.6)	C00002660
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00002645
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00002645
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00002645
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00002645
6329	SCN4A, HOKPP2, HYKPP, HYPP, NAC1A, Na(V)1.4, Nav1.4, SkM1	sodium channel, voltage-gated, type IV, alpha subunit	C00035128

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions