PCIDB

KNApSAcK Metabolite C00030878

Metabolite

KNApSAcK Entry

id C00030878
Name o-Cresol
CAS RN 95-48-7
Standard InChI InChI=1S/C7H8O/c1-6-4-2-3-5-7(6)8/h2-5,8H,1H3
Standard InChI (Main Layer) InChI=1S/C7H8O/c1-6-4-2-3-5-7(6)8/h2-5,8H,1H3

Cluster

Phytochemical cluster
KCF-S cluster No. 1546

Link

ChEMBL

By standard InChI CHEMBL46931
By standard InChI Main Layer CHEMBL46931

KEGG

By LinkDB C01542

CTD

By CAS RN C034047

Species

Summary

Plant class

class name count
rosids 2

Family

family name count
Meliaceae 1
Brassicaceae 1

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Brassica hirta 3728 Brassicaceae rosids Viridiplantae
Melia azadirach 155640 Meliaceae rosids Viridiplantae

Human Protein / Gene in interaction

4 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein CHEMBL46931 CHEMBL1794584 (1)
2 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein CHEMBL46931 CHEMBL2114810 (1)
7 / 3
Q96RI1 Bile acid receptor NR1H4 CHEMBL46931 CHEMBL1794415 (1)
0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein CHEMBL46931 CHEMBL2114890 (2)
0 / 0

CTD interaction (1)

compound gene gene name gene description interaction interaction type form reference
pmid
C034047 213 ALB
PRO0883
PRO0903
PRO1341
albumin 2-cresol binds to ALB protein affects binding
protein 11334365

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (9)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#114500 Colorectal cancer; crc P84022
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092

KEGG DISEASE (3)

KEGG disease name UniProt
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)

Diseases related to CTD interactions

4 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D001836 C034047 Body Weight Changes marker/mechanism
12820538
D017449 C034047 Dermatitis, Allergic Contact marker/mechanism
12478535
D014202 C034047 Tremor marker/mechanism
12820538
D015431 C034047 Weight Loss marker/mechanism
21705299