PCIDB

KNApSAcK Metabolite C00000207

Metabolite

KNApSAcK Entry

id C00000207
Name Benzoic acid
CAS RN 65-85-0
Standard InChI InChI=1S/C7H6O2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H,8,9)
Standard InChI (Main Layer) InChI=1S/C7H6O2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H,8,9)

Cluster

Phytochemical cluster
KCF-S cluster No. 2192

Link

ChEMBL

By standard InChI CHEMBL541
By standard InChI Main Layer CHEMBL541

KEGG

By LinkDB C00180

CTD

By CAS RN D019817

Species

Summary

Plant class

class name count
rosids 11
eudicotyledons 5
Liliopsida 4
asterids 4
Magnoliophyta 3
Euphyllophyta 1
Spermatophyta 1

Family (Top 10)

family name count
Fabaceae 5
Paeoniaceae 4
Asteraceae 2
Brassicaceae 2
Annonaceae 2
Rutaceae 1
Asparagaceae 1
Colchicaceae 1
Petiveriaceae 1
Apocynaceae 1

List (29)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Arabidopsis thaliana 3702 Brassicaceae rosids Viridiplantae
Begonia nantoensis 78253 Begoniaceae rosids Viridiplantae
Brassica hirta 3728 Brassicaceae rosids Viridiplantae
Burchardia multiflora 244022 Colchicaceae Liliopsida Viridiplantae
Catharanthus roseus 4058 Apocynaceae asterids Viridiplantae
Dalbergia cochinchinensis 106130 Fabaceae rosids Viridiplantae
Dalbergia spruceana 53862 Fabaceae rosids Viridiplantae
Hibiscus taiwanensis 47605 Malvaceae rosids Viridiplantae
Homalium cochinchinensis 179710 Salicaceae rosids Viridiplantae
Lemna paucicostata 89585 Araceae Liliopsida Viridiplantae
Onosma hispida 411249 Boraginaceae asterids Viridiplantae
Paeonia albiflora 35924 Paeoniaceae eudicotyledons Viridiplantae
Paeonia hybrida 13625 Paeoniaceae eudicotyledons Viridiplantae
Paeonia peregrina 40717 Paeoniaceae eudicotyledons Viridiplantae
Paeonia suffruticosa 45171 Paeoniaceae eudicotyledons Viridiplantae
Persea americana 3435 Lauraceae Magnoliophyta Viridiplantae
Petiveria alliacea 46142 Petiveriaceae eudicotyledons Viridiplantae
Phaseolus vulgaris 3885 Fabaceae rosids Viridiplantae
Phellodendron japonicum MAXIM 68553 Rutaceae rosids Viridiplantae
Posidonia oceanica 55489 Posidoniaceae Liliopsida Viridiplantae
Pteridium aquilinum 32101 Dennstaedtiaceae Euphyllophyta Viridiplantae
Rhaponticum carthamoides 362630 Asteraceae asterids Viridiplantae
Senna obtusifolia 346985 Fabaceae rosids Viridiplantae
Taraxacum formosanum 170733 Asteraceae asterids Viridiplantae
Taxus baccata 25629 Taxaceae Spermatophyta Viridiplantae
Trifolium incarnatum 60916 Fabaceae rosids Viridiplantae
Tupistra chinensis 100497 Asparagaceae Liliopsida Viridiplantae
Uvaria angolensis 672961 Annonaceae Magnoliophyta Viridiplantae
Uvaria mocali 174969 Annonaceae Magnoliophyta Viridiplantae

Human Protein / Gene in interaction

97 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL541 CHEMBL1909136 (2)
1 / 0
O94956 Solute carrier organic anion transporter family member 2B1 Unclassified protein CHEMBL541 CHEMBL2077868 (1)
0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor CHEMBL541 CHEMBL1909139 (2)
0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase CHEMBL541 CHEMBL1909131 (2)
0 / 3
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) CHEMBL541 CHEMBL1909190 (2)
2 / 2
P08246 Neutrophil elastase S1A CHEMBL541 CHEMBL1909195 (2)
2 / 1
P33765 Adenosine receptor A3 Adenosine receptor CHEMBL541 CHEMBL1909215 (2)
0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 CHEMBL541 CHEMBL1909201 (2)
0 / 0
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor CHEMBL541 CHEMBL1909176 (2)
0 / 0
P29466 Caspase-1 C14 CHEMBL541 CHEMBL1909193 (2)
0 / 0
P17252 Protein kinase C alpha type Alpha CHEMBL541 CHEMBL1909198 (2)
0 / 0
P27361 Mitogen-activated protein kinase 3 Erk CHEMBL541 CHEMBL1909199 (2)
0 / 0
P14780 Matrix metalloproteinase-9 M10A CHEMBL541 CHEMBL1909197 (2)
2 / 2
Q99489 D-aspartate oxidase Enzyme CHEMBL541 CHEMBL2327933 (1)
0 / 0
P16473 Thyrotropin receptor Glycohormone receptor CHEMBL541 CHEMBL1614281 (1) CHEMBL1614361 (1)
3 / 2
P00918 Carbonic anhydrase 2 Lyase CHEMBL541 CHEMBL1909123 (2)
1 / 2
P07550 Beta-2 adrenergic receptor Adrenergic receptor CHEMBL541 CHEMBL1909092 (2)
0 / 1
P21397 Amine oxidase [flavin-containing] A Oxidoreductase CHEMBL541 CHEMBL1909169 (2)
1 / 1
P25021 Histamine H2 receptor Histamine receptor CHEMBL541 CHEMBL1909157 (2)
0 / 0
P35367 Histamine H1 receptor Histamine receptor CHEMBL541 CHEMBL1909156 (2)
0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine CHEMBL541 CHEMBL1909143 (2)
1 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor CHEMBL541 CHEMBL1909174 (2)
0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor CHEMBL541 CHEMBL1909090 (2)
0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor CHEMBL541 CHEMBL1909093 (2)
0 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor CHEMBL541 CHEMBL1909127 (2)
0 / 0
Q9UQ49 Sialidase-3 Enzyme CHEMBL541 CHEMBL751097 (1)
0 / 0
P06241 Tyrosine-protein kinase Fyn Src CHEMBL541 CHEMBL1909204 (2)
0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr CHEMBL541 CHEMBL1909202 (2)
0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL541 CHEMBL1909135 (2)
0 / 1
P14920 D-amino-acid oxidase Enzyme CHEMBL541 CHEMBL2327779 (1) CHEMBL2327788 (1)
CHEMBL2327791 (1) CHEMBL2327928 (1)
CHEMBL2327931 (1) CHEMBL2327932 (2)
0 / 0
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily CHEMBL541 CHEMBL1909203 (2)
1 / 11
P14416 D(2) dopamine receptor Dopamine receptor CHEMBL541 CHEMBL1909140 (2)
2 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase CHEMBL541 CHEMBL1909130 (2)
0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor CHEMBL541 CHEMBL1909120 (2)
0 / 0
P41145 Kappa-type opioid receptor Opioid receptor CHEMBL541 CHEMBL1909181 (2)
0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor CHEMBL541 CHEMBL1909164 (2)
0 / 0
P29274 Adenosine receptor A2a Adenosine receptor CHEMBL541 CHEMBL1909214 (2)
0 / 0
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor CHEMBL541 CHEMBL1909175 (2)
0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor CHEMBL541 CHEMBL1909096 (2)
1 / 1
P17948 Vascular endothelial growth factor receptor 1 Vegfr CHEMBL541 CHEMBL1909118 (2)
0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor CHEMBL541 CHEMBL1909166 (2)
1 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 CHEMBL541 CHEMBL1909133 (2)
0 / 0
O60656 UDP-glucuronosyltransferase 1-9 Enzyme CHEMBL541 CHEMBL1908086 (1)
0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase CHEMBL541 CHEMBL1909158 (2)
0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor CHEMBL541 CHEMBL1909088 (2)
0 / 0
P21917 D(4) dopamine receptor Dopamine receptor CHEMBL541 CHEMBL1909142 (2)
0 / 0
P30988 Calcitonin receptor Calcitonin receptor CHEMBL541 CHEMBL1909101 (2)
0 / 0
P35462 D(3) dopamine receptor Dopamine receptor CHEMBL541 CHEMBL1909141 (2)
1 / 0
P41143 Delta-type opioid receptor Opioid receptor CHEMBL541 CHEMBL1909180 (2)
0 / 0
Q92731 Estrogen receptor beta NR3A2 CHEMBL541 CHEMBL1909146 (2)
0 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor CHEMBL541 CHEMBL1909104 (2)
0 / 0
P25101 Endothelin-1 receptor Endothelin receptor CHEMBL541 CHEMBL1909144 (2)
0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor CHEMBL541 CHEMBL1909100 (2)
0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor CHEMBL541 CHEMBL1909167 (2)
1 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor CHEMBL541 CHEMBL1909129 (2)
0 / 0
P08311 Cathepsin G S1A CHEMBL541 CHEMBL1909194 (2)
0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor CHEMBL541 CHEMBL1909110 (2)
1 / 0
P03956 Interstitial collagenase M10A CHEMBL541 CHEMBL1909196 (2)
0 / 1
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor CHEMBL541 CHEMBL1909119 (2)
0 / 0
Q9GZT4 Serine racemase Enzyme CHEMBL541 CHEMBL2327930 (1)
0 / 0
P04150 Glucocorticoid receptor NR3C1 CHEMBL541 CHEMBL1909150 (2)
0 / 1
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor CHEMBL541 CHEMBL1909171 (2)
2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor CHEMBL541 CHEMBL1909170 (2)
0 / 0
P21554 Cannabinoid receptor 1 Cannabinoid receptor CHEMBL541 CHEMBL1909122 (2)
0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin CHEMBL541 CHEMBL1909109 (2)
2 / 0
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily CHEMBL541 CHEMBL1909205 (2)
5 / 10
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor CHEMBL541 CHEMBL1909172 (2)
1 / 0
P21452 Substance-K receptor Neurokinin receptor CHEMBL541 CHEMBL1909114 (2)
0 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor CHEMBL541 CHEMBL1909125 (2)
0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor CHEMBL541 CHEMBL1909126 (2)
3 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor CHEMBL541 CHEMBL1909108 (2)
0 / 0
P41597 C-C chemokine receptor type 2 CC chemokine receptor CHEMBL541 CHEMBL1909124 (2)
1 / 0
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL541 CHEMBL1909200 (2)
0 / 0
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme CHEMBL541 CHEMBL1909207 (2)
2 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL541 CHEMBL1909132 (2)
0 / 0
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A CHEMBL541 CHEMBL1909186 (2)
0 / 0
P03372 Estrogen receptor NR3A1 CHEMBL541 CHEMBL1909145 (2)
1 / 1
P08588 Beta-1 adrenergic receptor Adrenergic receptor CHEMBL541 CHEMBL1909091 (2)
1 / 0
P22303 Acetylcholinesterase Hydrolase CHEMBL541 CHEMBL1909212 (2)
1 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor CHEMBL541 CHEMBL1909211 (2)
0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor CHEMBL541 CHEMBL1909105 (2)
0 / 0
P35372 Mu-type opioid receptor Opioid receptor CHEMBL541 CHEMBL1909182 (2)
0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor CHEMBL541 CHEMBL1909173 (2)
0 / 0
P25103 Substance-P receptor Neurokinin receptor CHEMBL541 CHEMBL1909113 (2)
0 / 0
P25105 Platelet-activating factor receptor PAF receptor CHEMBL541 CHEMBL1909187 (2)
0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor CHEMBL541 CHEMBL1909168 (2)
0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL541 CHEMBL1909134 (2)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL541 CHEMBL1909138 (2)
0 / 1
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 CHEMBL541 CHEMBL1909137 (2)
0 / 0
P19224 UDP-glucuronosyltransferase 1-6 Enzyme CHEMBL541 CHEMBL1908083 (1)
0 / 0
P23975 Sodium-dependent noradrenaline transporter Norepinephrine CHEMBL541 CHEMBL1909094 (2)
1 / 1
P25100 Alpha-1D adrenergic receptor Adrenergic receptor CHEMBL541 CHEMBL1909087 (2)
0 / 0
P30542 Adenosine receptor A1 Adenosine receptor CHEMBL541 CHEMBL1909213 (2)
0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor CHEMBL541 CHEMBL1909089 (2)
0 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 CHEMBL541 CHEMBL1909116 (2)
1 / 1
P06239 Tyrosine-protein kinase Lck Src CHEMBL541 CHEMBL1909206 (2)
0 / 1
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor CHEMBL541 CHEMBL1909128 (2)
0 / 0

CTD interaction (28)

compound gene gene name gene description interaction interaction type form reference
pmid
D019817 231 AKR1B1
ADR
ALDR1
ALR2
AR
aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21) Benzoic Acid results in increased expression of AKR1B1 mRNA increases expression
mRNA 20566472
D019817 57016 AKR1B10
AKR1B11
AKR1B12
ALDRLn
ARL-1
ARL1
HIS
HSI
aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2) Benzoic Acid results in increased expression of AKR1B10 mRNA increases expression
mRNA 20566472
D019817 1645 AKR1C1
2-ALPHA-HSD
20-ALPHA-HSD
C9
DD1
DD1/DD2
DDH
DDH1
H-37
HAKRC
HBAB
MBAB
aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112) Benzoic Acid results in increased expression of AKR1C1 mRNA increases expression
mRNA 20566472
D019817 8644 AKR1C3
DD3
DDX
HA1753
HAKRB
HAKRe
HSD17B5
PGFS
hluPGFS
aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357) Benzoic Acid results in increased expression of AKR1C3 mRNA increases expression
mRNA 20566472
D019817 2235 FECH
EPP
FCE
ferrochelatase (EC:4.99.1.1) Benzoic Acid results in increased expression of FECH mRNA increases expression
mRNA 20566472
D019817 2512 FTL
NBIA3
ferritin, light polypeptide Benzoic Acid results in increased expression of FTL mRNA increases expression
mRNA 20566472
D019817 2539 G6PD
G6PD1
glucose-6-phosphate dehydrogenase (EC:1.1.1.49) Benzoic Acid results in increased expression of G6PD mRNA increases expression
mRNA 20566472
D019817 2729 GCLC
GCL
GCS
GLCL
GLCLC
glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) Benzoic Acid results in increased expression of GCLC mRNA increases expression
mRNA 20566472
D019817 2730 GCLM
GLCLR
glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2) Benzoic Acid results in increased expression of GCLM mRNA increases expression
mRNA 20566472
D019817 2936 GSR
glutathione reductase (EC:1.8.1.7) Benzoic Acid results in increased expression of GSR mRNA increases expression
mRNA 20566472
D019817 2938 GSTA1
GST2
GSTA1-1
GTH1
glutathione S-transferase alpha 1 (EC:2.5.1.18) Benzoic Acid results in increased activity of GSTA1 protein mutant form increases activity
protein 10329179
D019817 3162 HMOX1
HMOX1D
HO-1
HSP32
bK286B10
heme oxygenase (decycling) 1 (EC:1.14.99.3) Benzoic Acid results in increased expression of HMOX1 mRNA increases expression
mRNA 20566472
D019817 4097 MAFG
hMAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G Benzoic Acid results in increased expression of MAFG mRNA increases expression
mRNA 20566472
D019817 4199 ME1
HUMNDME
MES
malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40) Benzoic Acid results in increased expression of ME1 mRNA increases expression
mRNA 20566472
D019817 4489 MT1A
MT1
MT1S
MTC
metallothionein 1A Benzoic Acid results in increased expression of MT1A mRNA increases expression
mRNA 20491607
D019817 4502 MT2A
MT2
metallothionein 2A Benzoic Acid results in increased expression of MT2A mRNA increases expression
mRNA 20491607
D019817 4846 NOS3
ECNOS
eNOS
nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) Benzoic Acid results in increased expression of NOS3 mRNA increases expression
mRNA 15740983
D019817 1728 NQO1
DHQU
DIA4
DTD
NMOR1
NMORI
QR1
NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) Benzoic Acid results in increased expression of NQO1 mRNA increases expression
mRNA 20566472
D019817 5226 PGD
6PGD
phosphogluconate dehydrogenase (EC:1.1.1.44) Benzoic Acid results in increased expression of PGD mRNA increases expression
mRNA 20566472
D019817 22949 PTGR1
LTB4DH
PGR1
ZADH3
prostaglandin reductase 1 (EC:1.3.1.48 1.3.1.74) Benzoic Acid results in increased expression of PTGR1 mRNA increases expression
mRNA 20566472
D019817 6566 SLC16A1
HHF7
MCT
MCT1
solute carrier family 16 (monocarboxylate transporter), member 1 morin inhibits the reaction [SLC16A1 protein results in increased uptake of Benzoic Acid] decreases reaction
/ increases uptake
protein 17976262
D019817 6566 SLC16A1
HHF7
MCT
MCT1
solute carrier family 16 (monocarboxylate transporter), member 1 naringenin inhibits the reaction [SLC16A1 protein results in increased uptake of Benzoic Acid] decreases reaction
/ increases uptake
protein 17976262
D019817 6566 SLC16A1
HHF7
MCT
MCT1
solute carrier family 16 (monocarboxylate transporter), member 1 Quercetin inhibits the reaction [SLC16A1 protein results in increased uptake of Benzoic Acid] decreases reaction
/ increases uptake
protein 17976262
D019817 6566 SLC16A1
HHF7
MCT
MCT1
solute carrier family 16 (monocarboxylate transporter), member 1 silybin inhibits the reaction [SLC16A1 protein results in increased uptake of Benzoic Acid] decreases reaction
/ increases uptake
protein 17976262
D019817 6566 SLC16A1
HHF7
MCT
MCT1
solute carrier family 16 (monocarboxylate transporter), member 1 SLC16A1 protein results in increased uptake of Benzoic Acid increases uptake
protein 17976262
D019817 140809 SRXN1
C20orf139
Npn3
SRX
SRX1
sulfiredoxin 1 (EC:1.8.98.2) Benzoic Acid results in increased expression of SRXN1 mRNA increases expression
mRNA 20566472
D019817 7295 TXN
TRDX
TRX
TRX1
thioredoxin Benzoic Acid results in increased expression of TXN mRNA increases expression
mRNA 20491607
D019817 7296 TXNRD1
GRIM-12
TR
TR1
TRXR1
TXNR
thioredoxin reductase 1 (EC:1.8.1.9) Benzoic Acid results in increased expression of TXNRD1 mRNA increases expression
mRNA 20566472

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (39)

OMIM preferred title UniProt
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#103780 Alcohol dependence P08172
P14416
P31645
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
#300615 Brunner syndrome P21397
#162800 Cyclic neutropenia P08246
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#615363 Estrogen resistance; estrr P03372
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#137800 Glioma susceptibility 1; glm1 P04626
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#603932 Intervertebral disc disease; idd P14780
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
#608516 Major depressive disorder; mdd P08172
%300852 Mental retardation, x-linked 88; mrx88 P50052
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#126200 Multiple sclerosis, susceptibility to; ms P08575
#159900 Myoclonic dystonia P14416
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#601665 Obesity P32245
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#607276 Resting heart rate, variation in P08588
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#190300 Tremor, hereditary essential, 1; etm1 P35462
#610379 West nile virus, susceptibility to P51681
#112100 Yt blood group antigen P22303

KEGG DISEASE (33)

KEGG disease name UniProt
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
Q92731 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00019 Pancreatic cancer P04626 (related)
H00027 Ovarian cancer P04626 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
H00046 Cholangiocarcinoma P04626 (related)
P35354 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00079 Asthma P07550 (related)
H00100 Neutropenic disorders P08246 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00025 Penile cancer P14780 (related)
P35354 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00548 Brunner syndrome P21397 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)

Diseases related to CTD interactions

1 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D003877 D019817 Dermatitis, Contact marker/mechanism
6221686