Hibiscus taiwanensis
Species
KNApSAcK Entry
| Organism name | Hibiscus taiwanensis |
|---|---|
| Genus | Hibiscus |
| Family | Malvaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Hibiscus |
|---|---|
| Linked NCBI taxonomy ID | 47605 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Malvaceae |
|---|---|
| ID | 3629 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (44)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00035942
|
3-oxo-Olean-12-en-28-oic acid
/ (+)-3-oxo-Olean-12-en-28-oic acid |
CHEMBL470029
CHEMBL574496 |
3 / 1 / 2 | No. 13 | No. 51 |
|
||
|
C00032041
|
Myricerol
|
CHEMBL498636
|
No. 13 | No. 51 |
|
|||
|
C00000627
|
(-)-Lirioresinol B
/ (-)-Syringaresinol |
CHEMBL361362
CHEMBL402653 |
1 / 0 / 0 | No. 38 | No. 21 |
|
||
|
C00023774
|
Fucostanol
/ Stigmasterol / Dihydro-beta-sitosterol / (24S)24-Ethylcholestain-3beta-ol |
CHEMBL66943
CHEMBL186373 CHEMBL400247 CHEMBL1568947 |
D013265
|
5 / 0 / 0 | 1 / 0 | No. 53 | No. 11 |
|
|
C00031433
|
Uncarinic acid A
/ (+)-Uncarinic acid A |
CHEMBL283043
CHEMBL30532 |
1 / 0 / 0 | No. 78 |
|
|||
|
C00032038
|
Myriceric acid A
|
C075745
|
No. 78 |
|
||||
|
C00031434
|
Uncarinic acid B
|
CHEMBL283043
CHEMBL30532 |
1 / 0 / 0 | No. 78 |
|
|||
|
C00031854
|
Hibicusin
/ (+)-Hibicusin |
No. 78 |
|
|||||
|
C00032039
|
Myriceric acid B
|
No. 78 |
|
|||||
|
C00032040
|
Myriceric acid C
|
No. 78 |
|
|||||
|
C00000672
|
Dihydrodehydrodiconiferyl alcohol
|
CHEMBL261907
CHEMBL253590 |
No. 215 | No. 23 |
|
|||
|
C00031384
|
Sinapinaldehyde
|
CHEMBL225067
|
No. 310 | No. 6 |
|
|||
|
C00031974
|
Lignocerylferulate
|
No. 447 |
|
|||||
|
C00002984
|
Cleomiscosin A
|
CHEMBL510091
|
C041934
|
No. 485 |
|
|||
|
C00031605
|
Aquillochin
/ Cleomiscosin C |
CHEMBL465491
|
No. 485 |
|
||||
|
C00025334
|
trans-Feruloyltyramine
/ N-trans-Feruloyltyramine / trans-N-Feruloyltyramine |
CHEMBL206555
CHEMBL451720 |
1 / 4 / 2 | No. 499 |
|
|||
|
C00025324
|
N-cis-Feruloyltyramine
/ cis-N-Feruloyltyramine |
CHEMBL206555
CHEMBL451720 |
1 / 4 / 2 | No. 499 |
|
|||
|
C00019308
|
Doursterol
/ Daucosterin / 3-O-beta-D-Glucopyranosyl sitosterol / beta-Sitosterol 3-O-beta-D-glucopyranoside |
CHEMBL197711
CHEMBL506678 CHEMBL2304043 |
C011015
|
5 / 4 / 2 | 0 / 3 | No. 520 |
|
|
|
C00000856
|
4-Hydroxybenzoic acid
/ p-Hydroxybenzoic acid |
CHEMBL441343
|
C038193
|
21 / 7 / 16 | 2 / 1 | No. 817 | No. 81 |
|
|
C00002499
|
Scopoletin
|
CHEMBL71851
|
D012603
|
48 / 37 / 34 | 9 / 0 | No. 864 | No. 25 |
|
|
C00002498
|
Scoparone
/ 6,7-Dimethoxycoumarin / Aesculetin dimethyl ether |
CHEMBL325864
|
C018145
|
4 / 2 / 2 | 6 / 0 | No. 864 | No. 25 |
|
|
C00032011
|
Methyl cis-ferulate
|
CHEMBL32969
|
No. 876 |
|
||||
|
C00029337
|
Methyl (E)-ferulate
/ Methyl trans-ferulate / (E)-Methyl-4-hydroxy-3-methoxycinnamate |
CHEMBL32969
|
No. 876 |
|
||||
|
C00002759
|
Methyl caffeate
|
CHEMBL17001
|
C042405
|
No. 876 |
|
|||
|
C00000615
|
Caffeic acid
|
CHEMBL145
CHEMBL1320034 |
68 / 64 / 63 | No. 904 | No. 6 |
|
||
|
C00000152
|
p-Coumaric acid
|
CHEMBL66879
CHEMBL2336752 |
C032171
|
23 / 13 / 18 | 6 / 1 | No. 904 | No. 6 |
|
|
C00002683
|
Vanillin
|
CHEMBL13883
|
18 / 8 / 9 | No. 1003 |
|
|||
|
C00002674
|
Syringic acid
/ 4-Hydroxy-3,5-dimethoxybenzoic acid |
CHEMBL1414
|
C001945
|
12 / 3 / 5 | No. 1073 |
|
||
|
C00002682
|
Vanillic acid
/ 3-Methoxy-4-hydroxybenzoic acid |
CHEMBL120568
|
D014641
|
5 / 3 / 3 | 5 / 0 | No. 1073 |
|
|
|
C00020125
|
Mansonone H
/ Helicquinone |
No. 1178 |
|
|||||
|
C00020121
|
Mansonone E
|
CHEMBL362672
|
No. 1178 |
|
||||
|
C00031634
|
Boehmenan
|
No. 1214 |
|
|||||
|
C00031413
|
threo-Carolignan E
|
No. 1214 |
|
|||||
|
C00031775
|
erythro-Carolignan E
|
No. 1214 |
|
|||||
|
C00002743
|
Ferulic acid
/ 3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid |
CHEMBL32749
|
C004999
|
110 / 52 / 40 | 16 / 6 | No. 1366 | No. 6 |
|
|
C00030768
|
Methyl vanillate
|
CHEMBL486214
|
No. 1936 |
|
||||
|
C00032013
|
Methyl p-formylbenzoate
|
CHEMBL1607943
|
7 / 8 / 9 | No. 2169 |
|
|||
|
C00000207
|
Benzoic acid
|
CHEMBL541
|
D019817
|
97 / 39 / 33 | 24 / 1 | No. 2192 |
|
|
|
C00032012
|
Methyl p-coumarate
/ Methyl p-hydroxycinnamate / Methyl 4-hydroxy cinnamate / 4-Hydroxycinnamic acid methyl ester |
CHEMBL146816
|
C057918
|
6 / 2 / 4 | No. 2416 |
|
||
|
C00020100
|
Gmelofuran
/ Hibiscone C |
No. 2871 |
|
|||||
|
C00031855
|
Hibicuslide B
/ (+)-Hibicuslide B |
No. 3356 |
|
|||||
|
C00031786
|
Ficusol
/ (-)-Ficusol / Methyl (S)-2-(4-hydroxy-3-methoxyphenyl)-3-hydroxypropanoate |
No. 5229 |
|
|||||
|
C00031856
|
Hibicutaiwanin
|
No. 5704 |
|
|||||
|
C00030975
|
p-Formylbenzoic acid
|
CHEMBL113897
|
C033525
|
2 / 0 / 0 | 1 / 0 | No. 6065 |
|
Human Protein / Gene in interactions
198 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P00918 | Carbonic anhydrase 2 | Lyase | C00000152 C00000207 C00000615 C00000856 C00002499 C00002674 C00002743 C00032012 | 1 / 2 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00000152 C00000615 C00000856 C00002499 C00002674 C00002743 C00032012 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00000152 C00000615 C00000856 C00002499 C00002674 C00002743 C00032012 | 0 / 1 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00000152 C00000615 C00000856 C00002499 C00002674 C00002743 C00032012 | 1 / 2 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00000152 C00000615 C00000856 C00002499 C00002674 C00002743 C00032012 | 0 / 0 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00000152 C00000615 C00000856 C00002674 C00002743 C00032012 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00000152 C00000207 C00000615 C00002682 C00002743 | 1 / 1 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00000152 C00000615 C00000856 C00002674 C00002743 | 0 / 0 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00000152 C00000615 C00000856 C00002674 C00002743 | 0 / 0 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000152 C00000207 C00000615 C00000856 C00002743 | 1 / 8 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00000152 C00000615 C00000856 C00002674 C00002743 | 0 / 0 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00000152 C00000615 C00000856 C00002674 C00002743 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000152 C00000207 C00000615 C00002499 C00002743 | 0 / 3 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00000152 C00000615 C00000856 C00002674 C00002743 | 1 / 1 |
| P15121 | Aldose reductase | Enzyme | C00000152 C00000615 C00002499 C00002674 C00002682 | 0 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00000152 C00000615 C00002743 C00025324 C00025334 | 4 / 2 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00000615 C00002499 C00002683 C00030975 C00032013 | 0 / 0 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00000207 C00000856 C00002499 C00002683 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000207 C00000615 C00002499 C00002743 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000207 C00000615 C00002499 C00002743 | 0 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000207 C00000615 C00002499 C00002743 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000207 C00000615 C00002499 C00002743 | 0 / 1 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000615 C00002499 C00019308 C00035942 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000207 C00000615 C00002499 C00002743 | 1 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00000207 C00002743 C00032013 | 0 / 1 |
| P06746 | DNA polymerase beta | Enzyme | C00000615 C00019308 C00023774 | 0 / 0 |
| Q13093 | Platelet-activating factor acetylhydrolase | Enzyme | C00000152 C00000615 C00002743 | 3 / 0 |
| P29466 | Caspase-1 | C14 | C00000207 C00002499 C00002743 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000207 C00000615 C00002743 | 0 / 0 |
| Q8TDS4 | Hydroxycarboxylic acid receptor 2 | Hydroxycarboxylic acid receptor | C00000152 C00000615 C00002743 | 0 / 0 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00000207 C00000615 C00002743 | 2 / 2 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000615 C00002499 C00002683 | 2 / 2 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00000207 C00000615 C00002743 | 2 / 2 |
| P22303 | Acetylcholinesterase | Hydrolase | C00000207 C00002499 C00002743 | 1 / 0 |
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00000856 C00002499 C00002683 | 0 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00000207 C00000615 C00002743 | 0 / 0 |
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00000207 C00000856 C00002683 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000615 C00002499 C00002743 | 0 / 0 |
| P34969 | 5-hydroxytryptamine receptor 7 | Serotonin receptor | C00002683 C00002743 C00023774 | 0 / 0 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00000207 C00002498 C00002743 | 1 / 1 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00000615 C00002499 C00002743 | 1 / 1 |
| P03956 | Interstitial collagenase | M10A | C00000207 C00000615 C00002743 | 0 / 1 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00000207 C00002743 | 0 / 0 |
| P51649 | Succinate-semialdehyde dehydrogenase, mitochondrial | Oxidoreductase | C00000856 C00002683 | 1 / 1 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00000615 C00032013 | 3 / 1 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00000615 C00002683 | 0 / 0 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00000207 C00002743 | 0 / 1 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000207 C00000615 | 3 / 2 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00000207 C00002743 | 0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00000207 C00002743 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00000207 C00002743 | 1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00000207 C00002743 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00000207 C00002743 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00000207 C00002743 | 0 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000615 C00002499 | 1 / 2 |
| O00255 | Menin | Unclassified protein | C00000615 C00002499 | 2 / 5 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00000207 C00002743 | 0 / 0 |
| Q9UQ49 | Sialidase-3 | Enzyme | C00000207 C00000856 | 0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00000207 C00002743 | 0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00000207 C00002743 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00000615 C00002683 | 1 / 1 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000615 C00002499 | 0 / 0 |
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00002499 C00002743 | 3 / 0 |
| Q9HAW7 | UDP-glucuronosyltransferase 1-7 | Enzyme | C00000856 C00002683 | 0 / 0 |
| Q12794 | Hyaluronidase-1 | Enzyme | C00000615 C00002743 | 1 / 2 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00000207 C00002743 | 0 / 0 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00000207 C00002743 | 0 / 1 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00000207 C00002743 | 2 / 0 |
| P17516 | Aldo-keto reductase family 1 member C4 | Enzyme | C00000152 C00000615 | 1 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00000207 C00002743 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00000207 C00002743 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00000207 C00002743 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00000207 C00002743 | 0 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00000207 C00002743 | 1 / 1 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00000207 C00002743 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00000207 C00002743 | 1 / 1 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00000207 C00002743 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00000207 C00002743 | 1 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00000207 C00002743 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00000207 C00002743 | 0 / 0 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00000207 C00002743 | 0 / 0 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00000207 C00002743 | 1 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00000615 C00002499 | 0 / 0 |
| P42330 | Aldo-keto reductase family 1 member C3 | Enzyme | C00000152 C00000615 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00000207 C00002743 | 0 / 0 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00000207 C00002743 | 1 / 1 |
| P10275 | Androgen receptor | NR3C4 | C00002683 C00032013 | 3 / 4 |
| O75496 | Geminin | Unclassified protein | C00002499 C00002743 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00000207 C00002743 | 0 / 0 |
| P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00002499 C00002743 | 0 / 0 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00000207 C00002743 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00000207 C00002743 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00000207 C00002743 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00000207 C00002743 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00000207 C00002743 | 1 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00000207 C00002743 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00000207 C00002743 | 0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00000207 C00002743 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00002683 C00030975 | 0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00000207 C00002743 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00000207 C00002743 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00000207 C00002743 | 1 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00000615 C00002499 | 1 / 1 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00002499 C00002743 | 5 / 1 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00000207 C00002743 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00000207 C00002743 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00000207 C00002743 | 1 / 0 |
| P52895 | Aldo-keto reductase family 1 member C2 | Enzyme | C00000152 C00000615 | 1 / 0 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00000207 C00002743 | 0 / 0 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00000207 C00002743 | 0 / 0 |
| P51580 | Thiopurine S-methyltransferase | Enzyme | C00000856 C00002682 | 1 / 1 |
| P19174 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | Enzyme | C00031433 C00031434 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00000615 C00032013 | 0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00000207 C00002743 | 0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00000207 C00002743 | 0 / 0 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00000207 C00002743 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00000207 C00002743 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00000207 C00002743 | 0 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00000207 C00002743 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00000207 C00002743 | 2 / 0 |
| P80404 | 4-aminobutyrate aminotransferase, mitochondrial | Transferase | C00000856 C00002683 | 1 / 1 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00000207 C00002743 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00000207 C00002743 | 1 / 0 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00000207 C00002743 | 0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00000207 C00002743 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00000207 C00002743 | 3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00000207 C00002743 | 0 / 0 |
| P06280 | Alpha-galactosidase A | Enzyme | C00000615 C00002499 | 1 / 1 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00000207 C00002743 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00000207 C00002743 | 0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00000207 C00002743 | 1 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00000207 C00002743 | 0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00000207 C00002743 | 2 / 1 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00000207 C00002743 | 0 / 0 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00000207 C00002743 | 0 / 0 |
| P08246 | Neutrophil elastase | S1A | C00000207 C00002743 | 2 / 1 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00000207 C00002743 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000615 C00002499 | 3 / 3 |
| Q04828 | Aldo-keto reductase family 1 member C1 | Enzyme | C00000152 C00000615 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00000207 C00002743 | 0 / 0 |
| O60218 | Aldo-keto reductase family 1 member B10 | Enzyme | C00000152 C00000615 | 0 / 0 |
| Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00000856 C00002499 | 0 / 0 |
| Q9Y4X1 | UDP-glucuronosyltransferase 2A1 | Enzyme | C00002499 C00002683 | 0 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00000207 C00002743 | 0 / 0 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00000615 C00002499 | 0 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00000207 C00002743 | 0 / 0 |
| P09884 | DNA polymerase alpha catalytic subunit | Transferase | C00023774 | 0 / 0 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00000615 | 5 / 2 |
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | C00002683 | 0 / 0 |
| P08253 | 72 kDa type IV collagenase | M10A | C00000615 | 1 / 3 |
| P56817 | Beta-secretase 1 | A1A | C00002498 | 0 / 0 |
| P78527 | DNA-dependent protein kinase catalytic subunit | Atypical serine/threonine protein kinase PIKK subfamily | C00002683 | 0 / 0 |
| P35236 | Tyrosine-protein phosphatase non-receptor type 7 | Tyr | C00000615 | 0 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00002683 | 0 / 0 |
| P00734 | Prothrombin | S1A | C00019308 | 4 / 2 |
| Q00796 | Sorbitol dehydrogenase | Enzyme | C00002499 | 0 / 0 |
| Q04206 | Transcription factor p65 | Transcription Factor | C00002499 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00002499 | 7 / 3 |
| P55210 | Caspase-7 | C14 | C00002499 | 0 / 0 |
| P35228 | Nitric oxide synthase, inducible | Enzyme | C00035942 | 1 / 1 |
| Q9GZT4 | Serine racemase | Enzyme | C00000207 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00002499 | 1 / 1 |
| O94956 | Solute carrier organic anion transporter family member 2B1 | Unclassified protein | C00000207 | 0 / 0 |
| P04062 | Glucosylceramidase | Enzyme | C00002499 | 6 / 4 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00002682 | 0 / 0 |
| O00519 | Fatty-acid amide hydrolase 1 | Enzyme | C00002683 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00000615 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00000615 | 0 / 0 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00019308 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000615 | 4 / 3 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00000615 | 0 / 0 |
| Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | Tyr | C00000615 | 4 / 2 |
| P42858 | Huntingtin | Unclassified protein | C00002682 | 1 / 1 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00002499 | 0 / 0 |
| P04406 | Glyceraldehyde-3-phosphate dehydrogenase | Enzyme | C00002499 | 0 / 0 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00032013 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00002499 | 0 / 0 |
| Q8N1Q1 | Carbonic anhydrase 13 | Lyase | C00002499 | 0 / 0 |
| Q99489 | D-aspartate oxidase | Enzyme | C00000207 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00032013 | 2 / 3 |
| P17706 | Tyrosine-protein phosphatase non-receptor type 2 | Tyr | C00035942 | 0 / 1 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00000627 | 0 / 0 |
| O75795 | UDP-glucuronosyltransferase 2B17 | Enzyme | C00002499 | 1 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00000615 | 11 / 10 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00000615 | 0 / 0 |
| P24298 | Alanine aminotransferase 1 | Enzyme | C00000615 | 0 / 0 |
| Q9GZT9 | Egl nine homolog 1 | Enzyme | C00000615 | 1 / 1 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00002499 | 0 / 0 |
| P14920 | D-amino-acid oxidase | Enzyme | C00000207 | 0 / 0 |
| P55789 | FAD-linked sulfhydryl oxidase ALR | Enzyme | C00002499 | 1 / 0 |
| P51452 | Dual specificity protein phosphatase 3 | Ser_Thr_Tyr | C00000615 | 0 / 0 |
| P08047 | Transcription factor Sp1 | Unclassified protein | C00019308 | 0 / 0 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00023774 | 0 / 0 |
| Q02880 | DNA topoisomerase 2-beta | Isomerase | C00023774 | 0 / 0 |
| P07900 | Heat shock protein HSP 90-alpha | Other cytosolic protein | C00000615 | 0 / 0 |
| P08238 | Heat shock protein HSP 90-beta | Other cytosolic protein | C00000615 | 0 / 0 |
| P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | C00002498 | 0 / 0 |
| P05091 | Aldehyde dehydrogenase, mitochondrial | Oxidoreductase | C00002498 | 1 / 1 |
55 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 54577 | UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G | UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) |
C00002499
C00002682
C00002743
|
| 54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) |
C00002499
C00002682
C00002743
|
| 4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) |
C00000152
C00000207
C00002682
|
| 54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) |
C00002499
C00002682
C00002743
|
| 54659 | UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C | UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) |
C00002499
C00002682
C00002743
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00000152
C00002743
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00000152
C00002743
|
| 6817 | SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) |
C00000152
C00000856
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00000152
C00002743
|
| 7299 | TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 | tyrosinase (EC:1.14.18.1) |
C00000152
C00002743
|
| 54578 | UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F | UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17) |
C00002499
|
| 5925 | RB1, OSRC, RB, p105-Rb, pRb, pp110 | retinoblastoma 1 |
C00002743
|
| 5742 | PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00002743
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00002743
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00002743
|
| 23621 | BACE1, ASP2, BACE, HSPC104 | beta-site APP-cleaving enzyme 1 (EC:3.4.23.46) |
C00002743
|
| 6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00002498
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00002498
|
| 4790 | NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
C00002498
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00002498
|
| 5966 | REL, C-Rel | v-rel avian reticuloendotheliosis viral oncogene homolog |
C00002498
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00002498
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00002743
|
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00002743
|
| 10327 | AKR1A1, ALDR1, ALR, ARM, DD3 | aldo-keto reductase family 1, member A1 (aldehyde reductase) (EC:1.1.1.2) |
C00030975
|
| 3952 | LEP, LEPD, OB, OBS | leptin |
C00000856
|
| 54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) |
C00002499
|
| 6319 | SCD, FADS5, MSTP008, SCD1, SCDOS | stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1) |
C00002743
|
| 54600 | UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I | UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) |
C00002499
|
| 7366 | UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 | UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) |
C00002499
|
| 7508 | XPC, RAD4, XP3, XPCC | xeroderma pigmentosum, complementation group C |
C00002499
|
| 10599 | SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6 | solute carrier organic anion transporter family, member 1B1 |
C00023774
|
| 231 | AKR1B1, ADR, ALDR1, ALR2, AR | aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21) |
C00000207
|
| 57016 | AKR1B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI | aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2) |
C00000207
|
| 1645 | AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB | aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112) |
C00000207
|
| 8644 | AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS | aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357) |
C00000207
|
| 2235 | FECH, EPP, FCE | ferrochelatase (EC:4.99.1.1) |
C00000207
|
| 2512 | FTL, NBIA3 | ferritin, light polypeptide |
C00000207
|
| 2539 | G6PD, G6PD1 | glucose-6-phosphate dehydrogenase (EC:1.1.1.49) |
C00000207
|
| 2729 | GCLC, GCL, GCS, GLCL, GLCLC | glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) |
C00000207
|
| 2730 | GCLM, GLCLR | glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2) |
C00000207
|
| 2936 | GSR | glutathione reductase (EC:1.8.1.7) |
C00000207
|
| 2938 | GSTA1, GST2, GSTA1-1, GTH1 | glutathione S-transferase alpha 1 (EC:2.5.1.18) |
C00000207
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00000207
|
| 4097 | MAFG, hMAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
C00000207
|
| 4199 | ME1, HUMNDME, MES | malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40) |
C00000207
|
| 4489 | MT1A, MT1, MT1S, MTC | metallothionein 1A |
C00000207
|
| 4502 | MT2A, MT2 | metallothionein 2A |
C00000207
|
| 1728 | NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 | NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) |
C00000207
|
| 5226 | PGD, 6PGD | phosphogluconate dehydrogenase (EC:1.1.1.44) |
C00000207
|
| 22949 | PTGR1, LTB4DH, PGR1, ZADH3 | prostaglandin reductase 1 (EC:1.3.1.48 1.3.1.74) |
C00000207
|
| 6566 | SLC16A1, HHF7, MCT, MCT1 | solute carrier family 16 (monocarboxylate transporter), member 1 |
C00000207
|
| 140809 | SRXN1, C20orf139, Npn3, SRX, SRX1 | sulfiredoxin 1 (EC:1.8.98.2) |
C00000207
|
| 7295 | TXN, TRDX, TRX, TRX1 | thioredoxin |
C00000207
|
| 7296 | TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR | thioredoxin reductase 1 (EC:1.8.1.9) |
C00000207
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (127)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #614279 | 46,xy sex reversal 8; srxy8 |
P17516
P52895 |
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #610251 | Alcohol sensitivity, acute |
P05091
|
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #600807 | Asthma, susceptibility to |
Q13093
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| #612560 | Bone mineral density quantitative trait locus 12; bmnd12 |
O75795
|
| #300615 | Brunner syndrome |
P21397
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
P22310 |
| #606785 | Crigler-najjar syndrome, type ii |
P22309
P22310 |
| #162800 | Cyclic neutropenia |
P08246
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #609820 | Erythrocytosis, familial, 3; ecyt3 |
Q9GZT9
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #301500 | Fabry disease |
P06280
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613163 | Gaba-transaminase deficiency |
P80404
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #143500 | Gilbert syndrome |
P22309
P22310 |
| #137800 | Glioma susceptibility 1; glm1 |
P04626
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #143100 | Huntington disease; hd |
P42858
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #147050 | Ige responsiveness, atopic; iger |
Q13093
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #607785 | Juvenile myelomonocytic leukemia; jmml |
Q06124
|
| #151100 | Leopard syndrome 1 |
Q06124
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #611162 | Malaria, susceptibility to |
P35228
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #156250 | Metachondromatosis; metcds |
Q06124
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #601492 | Mucopolysaccharidosis, type ix; mps9 |
Q12794
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #159900 | Myoclonic dystonia |
P14416
|
| #613076 | Myopathy, mitochondrial progressive, with congenital cataract, hearing loss, and developmental delay |
P55789
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #163950 | Noonan syndrome 1; ns1 |
Q06124
|
| #601665 | Obesity |
P32245
|
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #614278 | Platelet-activating factor acetylhydrolase deficiency; pafad |
Q13093
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601367 | Stroke, ischemic |
P00734
|
| #271980 | Succinic semialdehyde dehydrogenase deficiency; ssadhd |
P51649
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #610460 | Thiopurine s-methyltransferase deficiency |
P51580
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #278300 | Xanthinuria, type i |
P47989
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (97)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
Q16790 (marker) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P35228 (related) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) P08253 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
| H00223 | Inherited thrombophilia |
P00734
(related)
|
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) Q92731 (marker) |
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00019 | Pancreatic cancer |
P04626
(related)
|
| H00027 | Ovarian cancer |
P04626
(related)
|
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P35354 (related) |
| H01071 | Acute alcohol sensitivity |
P05091
(related)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00025 | Penile cancer |
P08253
(related)
P14780 (related) P35354 (related) |
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00408 | Type I diabetes mellitus |
P17706
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
Q99714 (related) |
| H00964 | Thiopurine S-methyltransferase deficiency (TPMT deficiency) |
P51580
(related)
|
| H00835 | Succinic semialdehyde dehydrogenase (SSADH) deficiency |
P51649
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H01257 | GABA-transaminase deficiency |
P80404
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00523 | Noonan syndrome and related disorders |
Q06124
(related)
|
| H01018 | Metachondromatosis |
Q06124
(related)
|
| H00133 | Mucopolysaccharidosis type IX (MPS9) |
Q12794
(related)
|
| H00421 | Mucopolysaccharidosis (MPS) |
Q12794
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00236 | Congenital polycythemia |
Q9GZT9
(related)
|
Diseases related to CTD interactions
11 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D008545 | Melanoma |
C00002743
C00000152 |
| D009203 | Myocardial Infarction |
C00002743
|
| D007249 | Inflammation |
C00002743
|
| D008106 | Liver Cirrhosis, Experimental |
C00002743
|
| D050197 | Atherosclerosis |
C00002743
|
| D002252 | Carbon Tetrachloride Poisoning |
C00002743
|
| D002493 | Central Nervous System Diseases |
C00019308
|
| D003072 | Cognition Disorders |
C00019308
|
| D013118 | Spinal Cord Diseases |
C00019308
|
| D012220 | Rhinitis |
C00000856
|
| D003877 | Dermatitis, Contact |
C00000207
|