KCF-S cluster No. 310 (22 metabolites)
Corresponding Phytochemical cluster No. 6
Plant Species
Cumulative plant class count
| class name | count |
|---|---|
| rosids | 27 |
| asterids | 24 |
| Liliopsida | 8 |
| Magnoliophyta | 5 |
| Spermatophyta | 4 |
| eudicotyledons | 2 |
Cumulative family count (Top 20)
| class name | count |
|---|---|
Gesneriaceae
|
5 |
|
Brassicaceae
|
5 |
|
Solanaceae
|
5 |
|
Fabaceae
|
4 |
|
Rubiaceae
|
4 |
|
Asteraceae
|
3 |
|
Oleaceae
|
3 |
|
Linaceae
|
2 |
|
Fagaceae
|
2 |
|
Juglandaceae
|
2 |
|
Malvaceae
|
2 |
|
Cupressaceae
|
2 |
|
Aceraceae
|
2 |
|
Acoraceae
|
2 |
|
Thymelaeaceae
|
2 |
|
Poaceae
|
2 |
|
Myrtaceae
|
2 |
|
Stemonaceae
|
1 |
|
Celastraceae
|
1 |
|
Magnoliaceae
|
1 |
KEGG BRITE br08003
Categories (2)
| br08003 Category | # of metabolite |
|---|---|
| Coniferyl alcohol derivatives | 2 |
| Sinapate derivatives | 4 |
metabolites link (10)
Metabolite list (22)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00000614
|
Coniferyl alcohol
|
CHEMBL501870
CHEMBL2088631 |
C010559
|
|
||
|
C00000620
|
Isoeugenol
|
CHEMBL193598
CHEMBL445206 CHEMBL2135887 |
C036643
|
93 / 36 / 31 | 44 / 1 |
|
|
C00002728
|
Coniferaldehyde
/ Coniferyl aldehyde / 4-Hydroxy-3-methoxycinnamaldehyde |
CHEMBL242529
CHEMBL1956165 |
C075384
|
1 / 1 / 1 |
|
|
|
C00002760
|
Methylisoeugenol
|
CHEMBL465829
CHEMBL1164609 |
|
|||
|
C00002775
|
Sinapaldehyde
/ Sinapic aldehyde |
CHEMBL225067
|
C075386
|
|
||
|
C00002778
|
Sinapyl alcohol
|
CHEMBL1800816
|
|
|||
|
C00007337
|
5-Hydroxyconiferyl alcohol
|
|
||||
|
C00007611
|
5-Hydroxyconiferyl aldehyde
|
|
||||
|
C00018882
|
2,3-Dimethoxy-5-(1E)-1-propenylphenol
|
CHEMBL489518
|
|
|||
|
C00029546
|
Varamol 106
/ 4-Vinyl guaiacol |
C014245
|
|
|||
|
C00031384
|
Sinapinaldehyde
|
CHEMBL225067
|
|
|||
|
C00031469
|
(E)-4-(3,4-dimethoxyphenyl)but-3-en-1-ol
/ (E)-4-(3,4-Dimethoxyphenyl)-3-buten-1-ol |
C053776
|
|
|||
|
C00032636
|
3,4-Dimethoxy-styrene
|
|
||||
|
C00033554
|
2-Methoxy-4-(3-methoxy-1-propenyl)-phenol
|
|
||||
|
C00034298
|
Syringenin
|
CHEMBL1800816
|
|
|||
|
C00035095
|
E-Isoeugenol
|
CHEMBL193598
CHEMBL445206 CHEMBL2135887 |
93 / 36 / 31 |
|
||
|
C00035131
|
Methyl isoeugenol
|
CHEMBL465829
CHEMBL1164609 |
C031050
|
3 / 0 |
|
|
|
C00035903
|
Z-Isoeugenol
|
CHEMBL193598
CHEMBL445206 CHEMBL2135887 |
93 / 36 / 31 |
|
||
|
C00035949
|
4-Hydroxy-3-methoxy-trans-cinnamaldehyde
|
CHEMBL242529
CHEMBL1956165 |
1 / 1 / 1 |
|
||
|
C00038240
|
3,4-Dimethoxycinnamaldehyde
|
CHEMBL465888
|
|
|||
|
C00039440
|
Isoferulaldehyde
|
CHEMBL53781
|
2 / 2 / 11 |
|
||
|
C00043990
|
trans-Coniferyl alcohol
|
CHEMBL501870
CHEMBL2088631 |
|
Human Protein / Gene in interactions
96 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000620 C00035095 C00035903 | 1 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00000620 C00035095 C00035903 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000620 C00035095 C00035903 | 0 / 3 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00000620 C00035095 C00035903 | 2 / 2 |
| P08246 | Neutrophil elastase | S1A | C00000620 C00035095 C00035903 | 2 / 1 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00000620 C00035095 C00035903 | 0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P29466 | Caspase-1 | C14 | C00000620 C00035095 C00035903 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00000620 C00035095 C00035903 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00000620 C00035095 C00035903 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00000620 C00035095 C00035903 | 2 / 2 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000620 C00035095 C00035903 | 0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00000620 C00035095 C00035903 | 1 / 2 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00000620 C00035095 C00035903 | 0 / 1 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00000620 C00035095 C00035903 | 1 / 1 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00000620 C00035095 C00035903 | 1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00000620 C00035095 C00035903 | 0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00000620 C00035095 C00035903 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000620 C00035095 C00035903 | 0 / 1 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00000620 C00035095 C00035903 | 0 / 1 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000620 C00035095 C00035903 | 1 / 8 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00000620 C00035095 C00035903 | 2 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00000620 C00035095 C00035903 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00000620 C00035095 C00035903 | 1 / 1 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00000620 C00035095 C00035903 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00000620 C00035095 C00035903 | 1 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00000620 C00035095 C00035903 | 0 / 0 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00000620 C00035095 C00035903 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00000620 C00035095 C00035903 | 1 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00000620 C00035095 C00035903 | 0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00000620 C00035095 C00035903 | 1 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00000620 C00035095 C00035903 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00000620 C00035095 C00035903 | 1 / 0 |
| P03956 | Interstitial collagenase | M10A | C00000620 C00035095 C00035903 | 0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000620 C00035095 C00035903 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00000620 C00035095 C00035903 | 0 / 1 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00000620 C00035095 C00035903 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00000620 C00035095 C00035903 | 2 / 0 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00000620 C00035095 C00035903 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00000620 C00035095 C00035903 | 1 / 0 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00000620 C00035095 C00035903 | 3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00000620 C00035095 C00035903 | 1 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000620 C00035095 C00035903 | 0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00000620 C00035095 C00035903 | 2 / 1 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00000620 C00035095 C00035903 | 1 / 1 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00000620 C00035095 C00035903 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00000620 C00035095 C00035903 | 1 / 1 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00000620 C00035095 C00035903 | 1 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00000620 C00035095 C00035903 | 1 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000620 C00035095 C00035903 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000620 C00035095 C00035903 | 0 / 1 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00000620 C00035095 C00035903 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000620 C00035095 C00035903 | 0 / 0 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00000620 C00035095 C00035903 | 1 / 1 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00000620 C00035095 C00035903 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000620 C00035095 C00035903 | 0 / 0 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00002728 C00035949 | 1 / 1 |
| P11802 | Cyclin-dependent kinase 4 | CMGC serine/threonine protein kinase family | C00039440 | 1 / 3 |
| P24385 | G1/S-specific cyclin-D1 | Other cytosolic protein | C00039440 | 1 / 8 |
47 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 2938 | GSTA1, GST2, GSTA1-1, GTH1 | glutathione S-transferase alpha 1 (EC:2.5.1.18) |
C00035131
|
| 2944 | GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1 | glutathione S-transferase mu 1 (EC:2.5.1.18) |
C00035131
|
| 2950 | GSTP1, DFN7, FAEES3, GST3, GSTP, PI | glutathione S-transferase pi 1 (EC:2.5.1.18) |
C00035131
|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00000620
|
| 231 | AKR1B1, ADR, ALDR1, ALR2, AR | aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21) |
C00000620
|
| 57016 | AKR1B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI | aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2) |
C00000620
|
| 1645 | AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB | aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112) |
C00000620
|
| 1646 | AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8 | aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357) |
C00000620
|
| 8644 | AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS | aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357) |
C00000620
|
| 847 | CAT | catalase (EC:1.11.1.6) |
C00000620
|
| 6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00000620
|
| 10850 | CCL27, ALP, CTACK, CTAK, ESKINE, ILC, PESKY, SCYA27 | chemokine (C-C motif) ligand 27 |
C00000620
|
| 29126 | CD274, B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1 | CD274 molecule |
C00000620
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00000620
|
| 2235 | FECH, EPP, FCE | ferrochelatase (EC:4.99.1.1) |
C00000620
|
| 2512 | FTL, NBIA3 | ferritin, light polypeptide |
C00000620
|
| 2539 | G6PD, G6PD1 | glucose-6-phosphate dehydrogenase (EC:1.1.1.49) |
C00000620
|
| 2729 | GCLC, GCL, GCS, GLCL, GLCLC | glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) |
C00000620
|
| 2730 | GCLM, GLCLR | glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2) |
C00000620
|
| 2878 | GPX3, GPx-P, GSHPx-3, GSHPx-P | glutathione peroxidase 3 (plasma) (EC:1.11.1.9) |
C00000620
|
| 2936 | GSR | glutathione reductase (EC:1.8.1.7) |
C00000620
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00000620
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00000620
|
| 23764 | MAFF, U-MAF, hMafF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
C00000620
|
| 4097 | MAFG, hMAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
C00000620
|
| 7975 | MAFK, NFE2U, P18 | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K |
C00000620
|
| 4199 | ME1, HUMNDME, MES | malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40) |
C00000620
|
| 4257 | MGST1, GST12, MGST, MGST-I | microsomal glutathione S-transferase 1 (EC:2.5.1.18) |
C00000620
|
| 4501 | MT1X, MT-1l, MT1 | metallothionein 1X |
C00000620
|
| 4790 | NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
C00000620
|
| 1728 | NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 | NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) |
C00000620
|
| 5226 | PGD, 6PGD | phosphogluconate dehydrogenase (EC:1.1.1.44) |
C00000620
|
| 22949 | PTGR1, LTB4DH, PGR1, ZADH3 | prostaglandin reductase 1 (EC:1.3.1.48 1.3.1.74) |
C00000620
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00000620
|
| 9021 | SOCS3, ATOD4, CIS3, Cish3, SOCS-3, SSI-3, SSI3 | suppressor of cytokine signaling 3 |
C00000620
|
| 6647 | SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer | superoxide dismutase 1, soluble (EC:1.15.1.1) |
C00000620
|
| 6648 | SOD2, IPOB, MNSOD, MVCD6 | superoxide dismutase 2, mitochondrial (EC:1.15.1.1) |
C00000620
|
| 6649 | SOD3, EC-SOD | superoxide dismutase 3, extracellular (EC:1.15.1.1) |
C00000620
|
| 140809 | SRXN1, C20orf139, Npn3, SRX, SRX1 | sulfiredoxin 1 (EC:1.8.98.2) |
C00000620
|
| 7097 | TLR2, CD282, TIL4 | toll-like receptor 2 |
C00000620
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00000620
|
| 10626 | TRIM16, EBBP | tripartite motif containing 16 |
C00000620
|
| 25828 | TXN2, MT-TRX, MTRX, TRX2 | thioredoxin 2 |
C00000620
|
| 7296 | TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR | thioredoxin reductase 1 (EC:1.8.1.9) |
C00000620
|
| 10587 | TXNRD2, SELZ, TR, TR-BETA, TR3, TRXR2 | thioredoxin reductase 2 (EC:1.8.1.9) |
C00000620
|
| 54578 | UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F | UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17) |
C00000620
|
| 7538 | ZFP36, G0S24, GOS24, NUP475, RNF162A, TIS11, TTP, zfp-36 | ZFP36 ring finger protein |
C00000620
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (39)
| OMIM | preferred title | UniProt |
|---|---|---|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| #300615 | Brunner syndrome |
P21397
|
| #162800 | Cyclic neutropenia |
P08246
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #137800 | Glioma susceptibility 1; glm1 |
P04626
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #609048 | Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 |
P11802
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #254500 | Myeloma, multiple |
P24385
|
| #159900 | Myoclonic dystonia |
P14416
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #601665 | Obesity |
P32245
|
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #278300 | Xanthinuria, type i |
P47989
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (37)
| KEGG | name | UniProt |
|---|---|---|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P24385 (related) P24385 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P24385 (related) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) P11802 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P11802 (related) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P24385 (related) P24385 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) Q92731 (marker) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00019 | Pancreatic cancer |
P04626
(related)
|
| H00027 | Ovarian cancer |
P04626
(related)
|
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) P24385 (related) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P35354 (related) |
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00038 | Malignant melanoma |
P11802
(related)
|
| H00025 | Penile cancer |
P14780
(related)
P35354 (related) |
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00006 | Hairy-cell leukemia |
P24385
(related)
|
| H00010 | Multiple myeloma |
P24385
(related)
|
| H00559 | von Hippel-Lindau syndrome |
P24385
(related)
|
| H00047 | Gallbladder cancer |
P24385
(marker)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|