Species

KNApSAcK Entry

Organism name Begonia nantoensis
Genus Begonia
Family Begoniaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Begonia nantoensis
Linked NCBI taxonomy ID 78253
Linked level species

Family

Family in NCBI taxonomy Begoniaceae
ID 3680

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (36)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002518 External link 512 Daidzin
/ Daidzoside
/ Daidzein 7-O-glucoside
CHEMBL486422
C013908
11 / 18 / 41 3 / 2 No. 2 No. 15
C00003776 External link 512 Lutein
/ (all-E)-Lutein
/ all-trans-(+)-Xanthophyll
/ (3R,3'R,6'R)-beta,epsilon-Carotene-3,3'-diol
CHEMBL173929
CHEMBL172477
CHEMBL1559643
CHEMBL1979448
D014975
4 / 2 / 3 7 / 2 No. 26 No. 59
C00029821 External link 512 Sitostenone
/ beta-Sitostenone
/ Stigmast-4-en-3-one
/ Stigmast-4-ene-3-one
CHEMBL66926
No. 53 No. 11
C00023774 External link 512 Fucostanol
/ Stigmasterol
/ Dihydro-beta-sitosterol
/ (24S)24-Ethylcholestain-3beta-ol
CHEMBL66943
CHEMBL186373
CHEMBL400247
CHEMBL1568947
D013265
5 / 0 / 0 1 / 0 No. 53 No. 11
C00003672 External link 512 Sitosterol
/ beta-sitosterl
/ (-)-beta-Sitosterol
/ Stigmast-5-en-3beta-ol
CHEMBL221542
CHEMBL1398443
CHEMBL1875388
17 / 19 / 12 No. 53 No. 11
C00003689 External link 512 Cucurbitacin I
CHEMBL387737
CHEMBL1317135
CHEMBL1717364
C038106
20 / 15 / 15 2 / 0 No. 220 No. 11
C00031749 External link 512 Dihydrocucurbitacin E
CHEMBL256519
No. 220 No. 11
C00031748 External link 512 Dihydrocucurbitacin B
CHEMBL553851
1 / 1 / 2 No. 220 No. 11
C00031750 External link 512 Dihydrocucurbitacin I
CHEMBL480111
1 / 0 / 0 No. 220 No. 11
C00003686 External link 512 Cucurbitacin E
CHEMBL455056
C102326
3 / 1 / 2 No. 220 No. 11
C00003687 External link 512 Cucurbitacin F
CHEMBL488312
CHEMBL1730681
C453923
8 / 4 / 1 No. 220 No. 11
C00003683 External link 512 Cucurbitacin B
CHEMBL367917
CHEMBL508185
CHEMBL507237
CHEMBL1708265
CHEMBL1728549
C041246
22 / 30 / 28 No. 220 No. 11
C00019308 External link 512 Doursterol
/ Daucosterin
/ 3-O-beta-D-Glucopyranosyl sitosterol
/ beta-Sitosterol 3-O-beta-D-glucopyranoside
CHEMBL197711
CHEMBL506678
CHEMBL2304043
C011015
5 / 4 / 2 0 / 3 No. 520
C00026659 External link 512 Begonanline
No. 807
C00002668 External link 512 Protocatechuic acid
/ 3,4-Dihydroxybenzoic acid
CHEMBL37537
C009091
33 / 19 / 19 2 / 0 No. 817 No. 81
C00000856 External link 512 4-Hydroxybenzoic acid
/ p-Hydroxybenzoic acid
CHEMBL441343
C038193
21 / 7 / 16 2 / 1 No. 817 No. 81
C00000152 External link 512 p-Coumaric acid
CHEMBL66879
CHEMBL2336752
C032171
23 / 13 / 18 6 / 1 No. 904 No. 6
C00000615 External link 512 Caffeic acid
CHEMBL145
CHEMBL1320034
68 / 64 / 63 No. 904 No. 6
C00002683 External link 512 Vanillin
CHEMBL13883
18 / 8 / 9 No. 1003
C00029476 External link 512 Eudesmic acid
/ Trimethylgallic acid
/ 3,4,5-Trimethoxybenzoic acid
CHEMBL377172
C005854
3 / 2 / 2 No. 1073
C00002682 External link 512 Vanillic acid
/ 3-Methoxy-4-hydroxybenzoic acid
CHEMBL120568
D014641
5 / 3 / 3 5 / 0 No. 1073
C00031480 External link 512 1,2,4-Trihydroxybenzene
C013038
66 / 2 No. 1590 No. 82
C00031089 External link 512 Protocatechuic acid methyl ester
CHEMBL486027
7 / 3 / 5 No. 1722
C00030768 External link 512 Methyl vanillate
CHEMBL486214
No. 1936
C00002657 External link 512 p-Formylphenol
/ 4-Hydroxybenzaldehyde
/ p-Hydroxybenzaldehyde
CHEMBL14193
C011483
3 / 2 / 2 No. 2076
C00030771 External link 512 Methylparaben
/ p-Methoxycarbonylphenol
CHEMBL325372
C015358
102 / 49 / 57 3 / 0 No. 2169
C00000207 External link 512 Benzoic acid
CHEMBL541
D019817
97 / 39 / 33 24 / 1 No. 2192
C00031476 External link 512 (S)-N-(1-Hydroxymethyl-2-phenylethyl)-benzamide
/ (-)-N-[(1S)-1-(Hydroxymethyl)-2-phenylethyl]-benzamide
CHEMBL469704
CHEMBL1731675
C014358
2 / 0 / 0 No. 2550
C00031444 External link 512 (-)-Auranamide
CHEMBL496238
CHEMBL1957889
CHEMBL1957890
CHEMBL1957891
CHEMBL1979730
No. 2605
C00000113 External link 512 Indole-3-carboxylic acid
CHEMBL387527
C012382
1 / 3 / 4 No. 3632
C00000208 External link 512 Nicotinic acid
CHEMBL573
CHEMBL2074803
D009525
100 / 38 / 34 48 / 110 No. 3681 No. 1
C00001513 External link 512 Uracil
CHEMBL566
D014498
2 / 1 / 1 1 / 8 No. 3873
C00002422 External link 512 5,7-Dihydroxychromone
/ 5,7-Dihydroxy-4-chromone
C080094
No. 3998 No. 15
C00031034 External link 512 Piperonylic acid
/ 3,4-Methylenedioxybenzoic acid
CHEMBL573781
C005455
2 / 0 / 0 No. 4093
C00032054 External link 512 Nantoamide
CHEMBL1440317
10 / 13 / 7 No. 7564
C00032010 External link 512 Methyl (S)-glycerate
/ (-)-Methyl (S)-glycerate
No. 8898

Human Protein / Gene in interactions

221 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P03372 Estrogen receptor NR3A1 C00000152 C00000207 C00000208 C00000615 C00002668 C00002682 C00003672 C00030771 1 / 1
P00918 Carbonic anhydrase 2 Lyase C00000152 C00000207 C00000208 C00000615 C00000856 C00002668 C00030771 C00031089 1 / 2
O75496 Geminin Unclassified protein C00001513 C00002668 C00003683 C00003687 C00003689 C00003776 C00029476 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002683 C00003683 C00003687 C00003689 C00030771 C00032054 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000207 C00000208 C00000615 C00003672 C00003689 C00030771 0 / 1
P00915 Carbonic anhydrase 1 Lyase C00000152 C00000615 C00000856 C00002668 C00030771 C00031089 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00000207 C00000208 C00000615 C00003672 C00003689 C00030771 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00000207 C00000208 C00000615 C00003672 C00003689 C00030771 1 / 1
O43570 Carbonic anhydrase 12 Lyase C00000152 C00000615 C00000856 C00002668 C00030771 C00031089 1 / 2
Q9ULX7 Carbonic anhydrase 14 Lyase C00000152 C00000615 C00000856 C00002668 C00030771 C00031089 0 / 0
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00000152 C00000207 C00000208 C00000615 C00000856 C00030771 1 / 8
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00000207 C00000208 C00000615 C00003672 C00003689 C00030771 0 / 1
Q16790 Carbonic anhydrase 9 Lyase C00000152 C00000615 C00000856 C00002668 C00030771 C00031089 0 / 1
P43166 Carbonic anhydrase 7 Lyase C00000152 C00000615 C00000856 C00002668 C00030771 C00031089 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000207 C00000208 C00000615 C00003672 C00003689 C00030771 1 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00000152 C00000207 C00000208 C00000615 C00030771 0 / 3
P14780 Matrix metalloproteinase-9 M10A C00000207 C00000208 C00000615 C00002668 C00030771 2 / 2
P28482 Mitogen-activated protein kinase 1 Erk C00000207 C00000208 C00000615 C00030771 C00031034 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00000208 C00003683 C00003687 C00003689 C00032054 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00002518 C00003683 C00003687 C00029476 C00032054 0 / 0
P03956 Interstitial collagenase M10A C00000207 C00000208 C00000615 C00002668 C00030771 0 / 1
P06746 DNA polymerase beta Enzyme C00000615 C00002668 C00003672 C00019308 C00023774 0 / 0
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00000207 C00000208 C00000615 C00030771 2 / 2
P25103 Substance-P receptor Neurokinin receptor C00000207 C00000208 C00030771 C00031476 0 / 0
P15121 Aldose reductase Enzyme C00000152 C00000615 C00002668 C00002682 0 / 0
P19224 UDP-glucuronosyltransferase 1-6 Enzyme C00000207 C00000856 C00002683 C00030771 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00002668 C00002682 C00030771 C00031476 0 / 0
O60656 UDP-glucuronosyltransferase 1-9 Enzyme C00000207 C00000856 C00002683 C00030771 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00000208 C00000615 C00002683 C00031034 0 / 0
Q99700 Ataxin-2 Unclassified protein C00003683 C00003687 C00003689 C00032054 1 / 1
P23280 Carbonic anhydrase 6 Lyase C00000152 C00000615 C00000856 C00002668 0 / 0
P20701 Integrin alpha-L Membrane receptor C00003683 C00003686 C00003689 C00031750 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00002518 C00003683 C00003687 C00032054 0 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00000207 C00000208 C00000615 C00030771 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00000615 C00002668 C00002683 C00030771 0 / 0
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00000207 C00000208 C00002518 C00030771 1 / 1
P22748 Carbonic anhydrase 4 Lyase C00000152 C00000615 C00000856 C00002668 1 / 1
P13945 Beta-3 adrenergic receptor Adrenergic receptor C00000207 C00000208 C00030771 0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00000615 C00030771 C00031089 1 / 1
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor C00000207 C00000208 C00030771 0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00000207 C00000208 C00030771 0 / 0
P51649 Succinate-semialdehyde dehydrogenase, mitochondrial Oxidoreductase C00000856 C00002657 C00002683 1 / 1
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A C00000207 C00000208 C00030771 0 / 0
P06239 Tyrosine-protein kinase Lck Src C00000207 C00000208 C00030771 0 / 1
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00000207 C00000208 C00030771 0 / 1
P22303 Acetylcholinesterase Hydrolase C00000207 C00000208 C00030771 1 / 0
P25021 Histamine H2 receptor Histamine receptor C00000207 C00000208 C00030771 0 / 0
P35367 Histamine H1 receptor Histamine receptor C00000207 C00000208 C00030771 0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine C00000207 C00000208 C00030771 1 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor C00000207 C00000208 C00030771 0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00000207 C00000208 C00030771 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00000207 C00000615 C00003672 3 / 2
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00000207 C00000208 C00030771 0 / 0
P07451 Carbonic anhydrase 3 Lyase C00000152 C00000615 C00000856 0 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 C00000207 C00000208 C00030771 1 / 1
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00000207 C00000208 C00030771 0 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor C00000207 C00000208 C00030771 0 / 0
P08246 Neutrophil elastase S1A C00000207 C00000208 C00030771 2 / 1
P06241 Tyrosine-protein kinase Fyn Src C00000207 C00000208 C00030771 0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr C00000207 C00000208 C00030771 0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor C00000207 C00000208 C00030771 0 / 0
P30542 Adenosine receptor A1 Adenosine receptor C00000207 C00000208 C00030771 0 / 0
O15118 Niemann-Pick C1 protein Unclassified protein C00002518 C00003683 C00032054 1 / 1
P35372 Mu-type opioid receptor Opioid receptor C00000207 C00000208 C00030771 0 / 0
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00000615 C00003672 C00019308 0 / 0
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00000207 C00000208 C00030771 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00003683 C00003689 C00003776 2 / 3
P14416 D(2) dopamine receptor Dopamine receptor C00000207 C00000208 C00030771 2 / 0
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme C00000207 C00000208 C00030771 2 / 1
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor C00000207 C00000208 C00030771 0 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00000207 C00000208 C00030771 0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor C00000207 C00000208 C00030771 0 / 0
P27361 Mitogen-activated protein kinase 3 Erk C00000207 C00000208 C00030771 0 / 0
P29274 Adenosine receptor A2a Adenosine receptor C00000207 C00000208 C00030771 0 / 0
P17252 Protein kinase C alpha type Alpha C00000207 C00000208 C00030771 0 / 0
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor C00000207 C00000208 C00030771 0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor C00000207 C00000208 C00030771 1 / 1
P17948 Vascular endothelial growth factor receptor 1 Vegfr C00000207 C00000208 C00030771 0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor C00000207 C00000208 C00030771 1 / 0
P29466 Caspase-1 C14 C00000207 C00000208 C00030771 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00000615 C00003776 C00032054 0 / 0
P23975 Sodium-dependent noradrenaline transporter Norepinephrine C00000207 C00000208 C00030771 1 / 1
P33765 Adenosine receptor A3 Adenosine receptor C00000207 C00000208 C00030771 0 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00000207 C00000208 C00030771 0 / 0
P41597 C-C chemokine receptor type 2 CC chemokine receptor C00000207 C00000208 C00030771 1 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00000207 C00000208 C00030771 0 / 0
Q8TDS4 Hydroxycarboxylic acid receptor 2 Hydroxycarboxylic acid receptor C00000152 C00000208 C00000615 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00003683 C00003687 C00003689 1 / 0
P25105 Platelet-activating factor receptor PAF receptor C00000207 C00000208 C00030771 0 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor C00000207 C00000208 C00030771 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00003683 C00003687 C00003689 2 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor C00000207 C00000208 C00030771 3 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00002518 C00003683 C00032054 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00000615 C00002683 C00003672 1 / 1
P51679 C-C chemokine receptor type 4 CC chemokine receptor C00000207 C00000208 C00030771 0 / 0
P21452 Substance-K receptor Neurokinin receptor C00000207 C00000208 C00030771 0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00000152 C00000615 C00000856 0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase C00000207 C00000208 C00030771 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00000207 C00000208 C00030771 0 / 0
P21917 D(4) dopamine receptor Dopamine receptor C00000207 C00000208 C00030771 0 / 0
P30988 Calcitonin receptor Calcitonin receptor C00000207 C00000208 C00030771 0 / 0
P35462 D(3) dopamine receptor Dopamine receptor C00000207 C00000208 C00030771 1 / 0
P41143 Delta-type opioid receptor Opioid receptor C00000207 C00000208 C00030771 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00000207 C00000208 C00030771 0 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor C00000207 C00000208 C00030771 0 / 0
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00000152 C00000615 C00000856 0 / 0
P25101 Endothelin-1 receptor Endothelin receptor C00000207 C00000208 C00030771 0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor C00000207 C00000208 C00030771 0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor C00000207 C00000208 C00030771 1 / 0
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00000207 C00000208 C00030771 1 / 0
P08588 Beta-1 adrenergic receptor Adrenergic receptor C00000207 C00000208 C00030771 1 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor C00000207 C00000208 C00030771 0 / 0
P08311 Cathepsin G S1A C00000207 C00000208 C00030771 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00000615 C00002668 C00003683 4 / 3
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00000207 C00000208 C00030771 1 / 0
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00000207 C00000208 C00030771 5 / 9
P40763 Signal transducer and activator of transcription 3 Transcription Factor C00003683 C00003686 C00031748 1 / 2
P10253 Lysosomal alpha-glucosidase Hydrolase C00000208 C00000615 C00002668 1 / 1
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor C00000207 C00000208 C00030771 0 / 0
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor C00000207 C00000208 C00030771 0 / 0
P80404 4-aminobutyrate aminotransferase, mitochondrial Transferase C00000856 C00002657 C00002683 1 / 1
Q16539 Mitogen-activated protein kinase 14 p38 C00000207 C00000208 C00030771 0 / 0
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 C00000207 C00000208 C00030771 0 / 0
Q16637 Survival motor neuron protein Unclassified protein C00002518 C00003683 C00003689 4 / 1
Q13093 Platelet-activating factor acetylhydrolase Enzyme C00000152 C00000615 C00002668 3 / 0
P31645 Sodium-dependent serotonin transporter Serotonin C00000207 C00000208 C00030771 2 / 0
P21554 Cannabinoid receptor 1 Cannabinoid receptor C00000207 C00000208 C00030771 0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor C00000207 C00000208 C00030771 0 / 0
P14679 Tyrosinase Oxidoreductase C00000152 C00000615 C00003672 4 / 2
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00000207 C00000208 C00030771 0 / 0
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00000207 C00000208 C00030771 2 / 0
P04150 Glucocorticoid receptor NR3C1 C00000207 C00000208 C00030771 0 / 1
P00734 Prothrombin S1A C00003672 C00019308 4 / 2
P51580 Thiopurine S-methyltransferase Enzyme C00000856 C00002682 1 / 1
P17516 Aldo-keto reductase family 1 member C4 Enzyme C00000152 C00000615 1 / 0
P52895 Aldo-keto reductase family 1 member C2 Enzyme C00000152 C00000615 1 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00000208 C00000615 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00000208 C00000615 0 / 0
P23528 Cofilin-1 Unclassified protein C00003686 C00003689 0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme C00002518 C00032054 4 / 2
O94956 Solute carrier organic anion transporter family member 2B1 Unclassified protein C00000207 C00000208 0 / 0
P42858 Huntingtin Unclassified protein C00002682 C00003683 1 / 1
Q06710 Paired box protein Pax-8 Unclassified protein C00003683 C00003689 1 / 2
P10275 Androgen receptor NR3C4 C00000113 C00002683 3 / 4
P42330 Aldo-keto reductase family 1 member C3 Enzyme C00000152 C00000615 0 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00000615 C00003689 0 / 0
Q9HAW8 UDP-glucuronosyltransferase 1-10 Enzyme C00000856 C00002683 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00000615 C00002668 0 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00002518 C00030771 7 / 37
Q9UBT6 DNA polymerase kappa Enzyme C00000615 C00002518 0 / 0
P08253 72 kDa type IV collagenase M10A C00000615 C00002668 1 / 3
Q9HAW7 UDP-glucuronosyltransferase 1-7 Enzyme C00000856 C00002683 0 / 0
Q04828 Aldo-keto reductase family 1 member C1 Enzyme C00000152 C00000615 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00000615 C00002683 2 / 2
Q9GZT9 Egl nine homolog 1 Enzyme C00000615 C00002668 1 / 1
O60218 Aldo-keto reductase family 1 member B10 Enzyme C00000152 C00000615 0 / 0
Q9UQ49 Sialidase-3 Enzyme C00000207 C00000856 0 / 0
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor C00002683 C00023774 0 / 0
P02545 Prelamin-A/C Unclassified protein C00000615 C00003683 11 / 10
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00000615 C00002668 0 / 0
P08047 Transcription factor Sp1 Unclassified protein C00003672 C00019308 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00003672 C00019308 0 / 0
P09884 DNA polymerase alpha catalytic subunit Transferase C00023774 0 / 0
Q9Y4X1 UDP-glucuronosyltransferase 2A1 Enzyme C00002683 0 / 0
Q9HAW9 UDP-glucuronosyltransferase 1-8 Enzyme C00000856 0 / 0
Q01453 Peripheral myelin protein 22 Unclassified protein C00000615 5 / 2
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00000615 3 / 3
P35236 Tyrosine-protein phosphatase non-receptor type 7 Tyr C00000615 0 / 0
Q96RI1 Bile acid receptor NR1H4 C00002683 0 / 0
P06280 Alpha-galactosidase A Enzyme C00000615 1 / 1
P51843 Nuclear receptor subfamily 0 group B member 1 Nuclear hormone receptor subfamily 0 group B member 1 C00029476 2 / 2
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00000615 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00003776 0 / 0
P14151 L-selectin Adhesion C00002668 0 / 0
P16109 P-selectin Adhesion C00002668 1 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00003683 0 / 0
P11308 Transcriptional regulator ERG Unclassified protein C00003689 1 / 2
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00002668 0 / 0
P49019 Hydroxycarboxylic acid receptor 3 Hydroxycarboxylic acid receptor C00000208 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00032054 7 / 3
Q9GZT4 Serine racemase Enzyme C00000207 0 / 0
O00519 Fatty-acid amide hydrolase 1 Enzyme C00002683 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00000615 0 / 0
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00030771 5 / 1
P07711 Cathepsin L1 C1A C00002668 0 / 0
Q9BXC0 Hydroxycarboxylic acid receptor 1 Hydroxycarboxylic acid receptor C00000208 0 / 0
P39748 Flap endonuclease 1 Enzyme C00003683 0 / 0
P14902 Indoleamine 2,3-dioxygenase 1 Enzyme C00002657 0 / 0
P16581 E-selectin Adhesion C00002668 0 / 0
P11387 DNA topoisomerase 1 Isomerase C00003683 0 / 0
P14920 D-amino-acid oxidase Enzyme C00000207 0 / 0
P08183 Multidrug resistance protein 1 drug C00003672 1 / 0
P51452 Dual specificity protein phosphatase 3 Ser_Thr_Tyr C00000615 0 / 0
P02768 Serum albumin Secreted protein C00002668 0 / 0
P05091 Aldehyde dehydrogenase, mitochondrial Oxidoreductase C00002518 1 / 1
P31939 Bifunctional purine biosynthesis protein PURH Enzyme C00003689 1 / 1
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00002683 0 / 0
P08254 Stromelysin-1 M10A C00002668 1 / 0
P10828 Thyroid hormone receptor beta NR1A2 C00000615 3 / 1
P80365 Corticosteroid 11-beta-dehydrogenase isozyme 2 Enzyme C00003672 1 / 1
Q12794 Hyaluronidase-1 Enzyme C00000615 1 / 2
Q99489 D-aspartate oxidase Enzyme C00000207 0 / 0
P24298 Alanine aminotransferase 1 Enzyme C00000615 0 / 0
Q13315 Serine-protein kinase ATM Atypical serine/threonine protein kinase PIKK subfamily C00003683 1 / 4
Q06124 Tyrosine-protein phosphatase non-receptor type 11 Tyr C00000615 4 / 2
P22894 Neutrophil collagenase M10A C00002668 0 / 0
P78527 DNA-dependent protein kinase catalytic subunit Atypical serine/threonine protein kinase PIKK subfamily C00002683 0 / 0
O00255 Menin Unclassified protein C00000615 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00000615 1 / 2
Q13951 Core-binding factor subunit beta Unclassified protein C00002668 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00002668 1 / 4
O76082 Solute carrier family 22 member 5 Unclassified protein C00000208 1 / 2
P11388 DNA topoisomerase 2-alpha Isomerase C00023774 0 / 0
Q02880 DNA topoisomerase 2-beta Isomerase C00023774 0 / 0
P07900 Heat shock protein HSP 90-alpha Other cytosolic protein C00000615 0 / 0
P08238 Heat shock protein HSP 90-beta Other cytosolic protein C00000615 0 / 0
P27338 Amine oxidase [flavin-containing] B Oxidoreductase C00002518 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00003672 2 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00003689 0 / 3
Q96FL8 Multidrug and toxin extrusion protein 1 Cation antiporter C00000208 0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00001513 1 / 1

158 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
3952 LEP, LEPD, OB, OBS leptin C00000208 C00000856 C00030771
4846 NOS3, ECNOS, eNOS nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) C00000152 C00000207 C00002682
6347 CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF chemokine (C-C motif) ligand 2 C00000208 C00031480
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00000152 C00003776
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00000208 C00003776
6817 SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) C00000152 C00000856
7296 TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR thioredoxin reductase 1 (EC:1.8.1.9) C00000207 C00031480
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00000208 C00031480
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00000208 C00031480
3569 IL6, BSF2, HGF, HSF, IFNB2, IL-6 interleukin 6 (interferon, beta 2) C00000208 C00031480
7299 TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 tyrosinase (EC:1.14.18.1) C00000152
6351 CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4 chemokine (C-C motif) ligand 4 C00031480
6352 CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP chemokine (C-C motif) ligand 5 C00031480
1436 CSF1R, C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R colony stimulating factor 1 receptor (EC:2.7.10.1) C00031480
2017 CTTN, EMS1 cortactin C00031480
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00031480
1593 CYP27A1, CP27, CTX, CYP27 cytochrome P450, family 27, subfamily A, polypeptide 1 (EC:1.14.13.15) C00031480
1571 CYP2E1, CPE1, CYP2E, P450-J, P450C2E cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) C00031480
3337 DNAJB1, HSPF1, Hdj1, Hsp40, RSPH16B, Sis1 DnaJ (Hsp40) homolog, subfamily B, member 1 C00031480
8661 EIF3A, EIF3, EIF3S10, P167, TIF32, eIF3-p170, eIF3-theta, p180, p185 eukaryotic translation initiation factor 3, subunit A C00031480
51386 EIF3L, EIF3EIP, EIF3S11, EIF3S6IP, HSPC021, HSPC025, MSTP005 eukaryotic translation initiation factor 3, subunit L C00031480
30001 ERO1L, ERO1-alpha, ERO1A, ERO1LA ERO1-like (S. cerevisiae) C00031480
55194 EVA1B, C1orf78, FAM176B, RP11-268J15.2 eva-1 homolog B (C. elegans) C00031480
2232 FDXR, ADXR ferredoxin reductase (EC:1.18.1.6) C00031480
126626 GABPB2 GA binding protein transcription factor, beta subunit 2 C00031480
2623 GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT GATA binding protein 1 (globin transcription factor 1) C00031480
2624 GATA2, DCML, MONOMAC, NFE1B GATA binding protein 2 C00031480
26088 GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 C00031480
2781 GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide C00031480
2812 GP1BB, BDPLT1, BS, CD42C, GPIBB glycoprotein Ib (platelet), beta polypeptide C00031480
2993 GYPA, CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN, MNS, PAS-2 glycophorin A (MNS blood group) C00031480
3043 HBB, CD113t-C, beta-globin hemoglobin, beta C00031480
3280 HES1, HES-1, HHL, HRY, bHLHb39 hes family bHLH transcription factor 1 C00031480
8339 HIST1H2BG, H2B.1A, H2B/a, H2BFA, dJ221C16.8 histone cluster 1, H2bg C00031480
8337 HIST2H2AA3, H2A, H2A.2, H2A/O, H2A/q, H2AFO, H2a-615, HIST2H2AA histone cluster 2, H2aa3 C00031480
3113 HLA-DPA1, DP(W3), DP(W4), HLA-DP1A, HLADP, HLASB, PLT1 major histocompatibility complex, class II, DP alpha 1 C00031480
3115 HLA-DPB1, DPB1, HLA-DP, HLA-DP1B, HLA-DPB major histocompatibility complex, class II, DP beta 1 C00031480
3145 HMBS, PBG-D, PBGD, PORC, UPS hydroxymethylbilane synthase (EC:2.5.1.61) C00031480
3320 HSP90AA1, EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2 heat shock protein 90kDa alpha (cytosolic), class A member 1 C00031480
3303 HSPA1A, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1 heat shock 70kDa protein 1A C00031480
3304 HSPA1B, HSP70-1B, HSP70-2 heat shock 70kDa protein 1B C00031480
3586 IL10, CSIF, GVHDS, IL-10, IL10A, TGIF interleukin 10 C00031480
1312 COMT catechol-O-methyltransferase (EC:2.1.1.6) C00002668
6356 CCL11, SCYA11 chemokine (C-C motif) ligand 11 C00031480
3674 ITGA2B, BDPLT16, BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3 integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) C00031480
3690 ITGB3, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) C00031480
3720 JARID2, JMJ jumonji, AT rich interactive domain 2 C00031480
3750 KCND1, KV4.1 potassium voltage-gated channel, Shal-related subfamily, member 1 C00031480
9817 KEAP1, INrf2, KLHL19 kelch-like ECH-associated protein 1 C00031480
8440 NCK2, GRB4, NCKbeta NCK adaptor protein 2 C00031480
4778 NFE2, NF-E2, p45 nuclear factor, erythroid 2 C00031480
22822 PHLDA1, DT1P1B11, PHRIP, TDAG51 pleckstrin homology-like domain, family A, member 1 C00031480
123 PLIN2, ADFP, ADRP perilipin 2 C00031480
4659 PPP1R12A, M130, MBS, MYPT1 protein phosphatase 1, regulatory subunit 12A C00031480
58497 PRUNE, DRES-17, DRES17, HTCD37 prune exopolyphosphatase (EC:3.6.1.1) C00031480
57403 RAB22A RAB22A, member RAS oncogene family C00031480
6138 RPL15, EC45, L15, RPL10, RPLY10, RPYL10 ribosomal protein L15 C00031480
6125 RPL5, DBA6, L5 ribosomal protein L5 C00031480
5176 SERPINF1, EPC-1, OI12, OI6, PEDF serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 C00031480
6452 SH3BP2, 3BP-2, 3BP2, CRBM, CRPM SH3-domain binding protein 2 C00031480
6653 SORL1, C11orf32, LR11, LRP9, SORLA, SorLA-1, gp250 sortilin-related receptor, L(DLR class) A repeats containing C00031480
8683 SRSF9, SFRS9, SRp30c serine/arginine-rich splicing factor 9 C00031480
7037 TFRC, CD71, T9, TFR, TFR1, TR, TRFR, p90 transferrin receptor C00031480
25907 TMEM158, BBP, RIS1, p40BBP transmembrane protein 158 (gene/pseudogene) C00031480
571 BACH1, BACH-1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 C00031480
7153 TOP2A, TOP2, TP2A topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) C00031480
9654 TTLL4 tubulin tyrosine ligase-like family, member 4 C00031480
10550 ARL6IP5, DERP11, GTRAP3-18, JWA, PRAF3, addicsin, hp22, jmx ADP-ribosylation-like factor 6 interacting protein 5 C00031480
217 ALDH2, ALDH-E2, ALDHI, ALDM aldehyde dehydrogenase 2 family (mitochondrial) (EC:1.2.1.3) C00002518
2353 FOS, AP-1, C-FOS, p55 FBJ murine osteosarcoma viral oncogene homolog C00002518
5241 PGR, NR3C3, PR progesterone receptor C00002518
2099 ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 estrogen receptor 1 C00030771
9870 AREL1, KIAA0317 apoptosis resistant E3 ubiquitin protein ligase 1 C00031480
7031 TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 trefoil factor 1 C00030771
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00000152
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00000152
158 ADSL, AMPS, ASASE, ASL adenylosuccinate lyase (EC:4.3.2.2) C00031480
47 ACLY, ACL, ATPCL, CLATP ATP citrate lyase (EC:2.3.3.8) C00031480
4363 ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 C00031480
6348 CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 chemokine (C-C motif) ligand 3 C00031480
3717 JAK2, JTK10, THCYT3 Janus kinase 2 (EC:2.7.10.2) C00003689
6774 STAT3, APRF, HIES signal transducer and activator of transcription 3 (acute-phase response factor) C00003689
19 ABCA1, ABC-1, ABC1, CERP, HDLDT1, TGD ATP-binding cassette, sub-family A (ABC1), member 1 C00000208
9370 ADIPOQ, ACDC, ACRP30, ADIPQTL1, ADPN, APM-1, APM1, GBP28 adiponectin, C1Q and collagen domain containing C00000208
183 AGT, ANHU, SERPINA8 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) C00000208
197 AHSG, A2HS, AHS, FETUA, HSGA alpha-2-HS-glycoprotein C00000208
335 APOA1 apolipoprotein A-I C00000208
338 APOB, FLDB, LDLCQ4 apolipoprotein B C00000208
506 ATP5B, ATPMB, ATPSB ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide (EC:3.6.3.14) C00000208
1050 CEBPA, C/EBP-alpha, CEBP CCAAT/enhancer binding protein (C/EBP), alpha C00000208
1052 CEBPD, C/EBP-delta, CELF, CRP3, NF-IL6-beta CCAAT/enhancer binding protein (C/EBP), delta C00000208
1376 CPT2, CPT1, CPTASE, IIAE4 carnitine palmitoyltransferase 2 (EC:2.3.1.21) C00000208
1401 CRP, PTX1 C-reactive protein, pentraxin-related C00000208
84649 DGAT2, ARAT, GS1999FULL diacylglycerol O-acyltransferase 2 (EC:2.3.1.20 2.3.1.76) C00000208
2149 F2R, CF2R, HTR, PAR-1, PAR1, TR coagulation factor II (thrombin) receptor C00000208
2194 FASN, FAS, OA-519, SDR27X1 fatty acid synthase (EC:2.3.1.85 2.3.1.38 2.3.1.39 2.3.1.41 3.1.2.14 4.2.1.59 1.1.1.100 1.3.1.39) C00000208
2641 GCG, GLP1, GLP2, GRPP glucagon C00000208
2688 GH1, GH, GH-N, GHN, IGHD1B, hGH-N growth hormone 1 C00000208
338442 HCAR2, GPR109A, HCA2, HM74a, HM74b, NIACR1, PUMAG, Puma-g hydroxycarboxylic acid receptor 2 C00000208
8843 HCAR3, GPR109B, HCA3, HM74, PUMAG, Puma-g hydroxycarboxylic acid receptor 3 C00000208
3383 ICAM1, BB2, CD54, P3.58 intercellular adhesion molecule 1 C00000208
3458 IFNG, IFG, IFI interferon, gamma C00000208
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00000208
3991 LIPE, HSL, LHS lipase, hormone-sensitive (EC:3.1.1.79) C00000208
4018 LPA, AK38, APOA, LP lipoprotein, Lp(a) (EC:3.4.21.-) C00000208
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00000208
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00000208
10062 NR1H3, LXR-a, LXRA, RLD-1 nuclear receptor subfamily 1, group H, member 3 C00000208
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) C00000208
5175 PECAM1, CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM platelet/endothelial cell adhesion molecule 1 C00000208
7941 PLA2G7, LDL-PLA2, LP-PLA2, PAFAD, PAFAH phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) (EC:3.1.1.47) C00000208
5465 PPARA, NR1C1, PPAR, PPARalpha, hPPAR peroxisome proliferator-activated receptor alpha C00000208
5468 PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma peroxisome proliferator-activated receptor gamma C00000208
10891 PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha C00000208
5563 PRKAA2, AMPK, AMPK2, AMPKa2, PRKAA protein kinase, AMP-activated, alpha 2 catalytic subunit (EC:2.7.11.1 2.7.11.27 2.7.11.31) C00000208
5729 PTGDR, AS1, ASRT1, DP, DP1, PTGDR1 prostaglandin D2 receptor (DP) C00000208
5730 PTGDS, L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2 prostaglandin D2 synthase 21kDa (brain) (EC:5.3.99.2) C00000208
5742 PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00000208
2023 ENO1, ENO1L1, MPB1, NNE, PPH enolase 1, (alpha) (EC:4.2.1.11) C00002668
56729 RETN, ADSF, FIZZ3, RETN1, RSTN, XCP1 resistin C00000208
949 SCARB1, CD36L1, CLA-1, CLA1, HDLQTL6, SR-BI, SRB1 scavenger receptor class B, member 1 C00000208
5054 SERPINE1, PAI, PAI-1, PAI1, PLANH1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 C00000208
7040 TGFB1, CED, DPD1, LAP, TGFB, TGFbeta transforming growth factor, beta 1 C00000208
7412 VCAM1, CD106, INCAM-100 vascular cell adhesion molecule 1 C00000208
7448 VTN, V75, VN, VNT vitronectin C00000208
10599 SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6 solute carrier organic anion transporter family, member 1B1 C00023774
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00001513
54575 UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) C00002682
54659 UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) C00002682
54577 UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) C00002682
54576 UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) C00002682
581 BAX, BCL2L4 BCL2-associated X protein C00003776
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00003776
598 BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS BCL2-like 1 C00003776
847 CAT catalase (EC:1.11.1.6) C00003776
595 CCND1, BCL1, D11S287E, PRAD1, U21B31 cyclin D1 C00003776
231 AKR1B1, ADR, ALDR1, ALR2, AR aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21) C00000207
57016 AKR1B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2) C00000207
1645 AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112) C00000207
8644 AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357) C00000207
2235 FECH, EPP, FCE ferrochelatase (EC:4.99.1.1) C00000207
2512 FTL, NBIA3 ferritin, light polypeptide C00000207
2539 G6PD, G6PD1 glucose-6-phosphate dehydrogenase (EC:1.1.1.49) C00000207
2729 GCLC, GCL, GCS, GLCL, GLCLC glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) C00000207
2730 GCLM, GLCLR glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2) C00000207
2936 GSR glutathione reductase (EC:1.8.1.7) C00000207
2938 GSTA1, GST2, GSTA1-1, GTH1 glutathione S-transferase alpha 1 (EC:2.5.1.18) C00000207
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00000207
4097 MAFG, hMAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G C00000207
4199 ME1, HUMNDME, MES malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40) C00000207
4489 MT1A, MT1, MT1S, MTC metallothionein 1A C00000207
4502 MT2A, MT2 metallothionein 2A C00000207
1728 NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) C00000207
5226 PGD, 6PGD phosphogluconate dehydrogenase (EC:1.1.1.44) C00000207
22949 PTGR1, LTB4DH, PGR1, ZADH3 prostaglandin reductase 1 (EC:1.3.1.48 1.3.1.74) C00000207
6566 SLC16A1, HHF7, MCT, MCT1 solute carrier family 16 (monocarboxylate transporter), member 1 C00000207
140809 SRXN1, C20orf139, Npn3, SRX, SRX1 sulfiredoxin 1 (EC:1.8.98.2) C00000207
7295 TXN, TRDX, TRX, TRX1 thioredoxin C00000207

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (149)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#300018 46,xy sex reversal 2; srxy2 P51843
#614279 46,xy sex reversal 8; srxy8 P17516
P52895
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#300200 Adrenal hypoplasia, congenital; ahc P51843
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#608688 Aicar transformylase/imp cyclohydrolase deficiency P31939
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#103780 Alcohol dependence P08172
P14416
P31645
#610251 Alcohol sensitivity, acute P05091
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#218030 Apparent mineralocorticoid excess; ame P80365
#600807 Asthma, susceptibility to Q13093
#208900 Ataxia-telangiectasia; at Q13315
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#300615 Brunner syndrome P21397
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#212140 Carnitine deficiency, systemic primary; cdsp O76082
#118300 Charcot-marie-tooth disease and deafness Q01453
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#118220 Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a Q01453
#114500 Colorectal cancer; crc P84022
#614466 Coronary heart disease, susceptibility to, 6; chds6 P08254
#218800 Crigler-najjar syndrome, type i P22309
#606785 Crigler-najjar syndrome, type ii P22309
#162800 Cyclic neutropenia P08246
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#609820 Erythrocytosis, familial, 3; ecyt3 Q9GZT9
#133239 Esophageal cancer P04637
#615363 Estrogen resistance; estrr P03372
#612219 Ewing sarcoma; es P11308
#301500 Fabry disease P06280
#600274 Frontotemporal dementia; ftd P10636
#613163 Gaba-transaminase deficiency P80404
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#143500 Gilbert syndrome P22309
#137800 Glioma susceptibility 1; glm1 O75874
P04626
#232300 Glycogen storage disease ii P10253
#139393 Guillain-barre syndrome, familial; gbs Q01453
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#143100 Huntington disease; hd P42858
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#147060 Hyper-ige recurrent infection syndrome, autosomal dominant P40763
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#143860 Hyperchlorhidrosis, isolated O43570
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#145900 Hypertrophic neuropathy of dejerine-sottas Q01453
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#218700 Hypothyroidism, congenital, nongoitrous, 2; chng2 Q06710
#147050 Ige responsiveness, atopic; iger Q13093
#612244 Inflammatory bowel disease 13; ibd13 P08183
#603932 Intervertebral disc disease; idd P14780
#607785 Juvenile myelomonocytic leukemia; jmml Q06124
#151100 Leopard syndrome 1 Q06124
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
P04637
#608516 Major depressive disorder; mdd P08172
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#174800 Mccune-albright syndrome; mas P63092
#300705 Mental retardation, x-linked 17; mrx17 Q99714
%300852 Mental retardation, x-linked 88; mrx88 P50052
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#156250 Metachondromatosis; metcds Q06124
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#601492 Mucopolysaccharidosis, type ix; mps9 Q12794
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#126200 Multiple sclerosis, susceptibility to; ms P08575
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#159900 Myoclonic dystonia P14416
#162500 Neuropathy, hereditary, with liability to pressure palsies; hnpp Q01453
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#257220 Niemann-pick disease, type c1; npc1 O15118
#163950 Noonan syndrome 1; ns1 Q06124
#601665 Obesity P32245
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#166350 Osseous heteroplasia, progressive; poh P63092
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260500 Papilloma of choroid plexus; cpp P04637
#260540 Parkinson-dementia syndrome P10636
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#614278 Platelet-activating factor acetylhydrolase deficiency; pafad Q13093
#614390 Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 P00734
#613679 Prothrombin deficiency, congenital P00734
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#607276 Resting heart rate, variation in P08588
#275210 Restrictive dermopathy, lethal P02545
#600852 Retinitis pigmentosa 17; rp17 P22748
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601367 Stroke, ischemic P00734
P16109
#271980 Succinic semialdehyde dehydrogenase deficiency; ssadhd P51649
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#610460 Thiopurine s-methyltransferase deficiency P51580
#188050 Thrombophilia due to thrombin defect; thph1 P00734
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#190300 Tremor, hereditary essential, 1; etm1 P35462
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#610379 West nile virus, susceptibility to P51681
#278300 Xanthinuria, type i P47989
#112100 Yt blood group antigen P22303

KEGG DISEASE (129)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
P04637 (marker)
Q16790 (marker)
H00286 Crohn's disease O76082 (related)
H00525 Disorders of fatty-acid oxidation O76082 (related)
H00016 Oral cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
P40763 (related)
H00017 Esophageal cancer P00533 (related)
P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
P04637 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
P04637 (related)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
P04637 (related)
P08253 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00223 Inherited thrombophilia P00734 (related)
H01254 Congenital prothrombin deficiency P00734 (related)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
P16473 (related)
Q06710 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
Q01453 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
P04637 (related)
Q92731 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00019 Pancreatic cancer P04626 (related)
P04637 (related)
P04637 (marker)
H00027 Ovarian cancer P04626 (related)
P04637 (related)
P38398 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
P04637 (related)
P38398 (related)
H00046 Cholangiocarcinoma P04626 (related)
P04637 (related)
P35354 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
Q01196 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
Q13315 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P08253 (related)
P14780 (related)
P35354 (related)
H00029 Vulvar cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
Q06710 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
P14679 (marker)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00044 Cancer of the anal canal P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H01071 Acute alcohol sensitivity P05091 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00125 Fabry disease P06280 (related)
H00079 Asthma P07550 (related)
H00100 Neutropenic disorders P08246 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00024 Prostate cancer P10275 (related)
P11308 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00035 Ewing's sarcoma P11308 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00548 Brunner syndrome P21397 (related)
H00208 Hyperbilirubinemia P22309 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H00966 AICA-ribosiduria P31939 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00107 Other well-defined immunodeficiency syndromes P40763 (related)
H00059 Huntington's disease (HD) P42858 (related)
H00192 Xanthinuria P47989 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
Q99714 (related)
H00964 Thiopurine S-methyltransferase deficiency (TPMT deficiency) P51580 (related)
H00835 Succinic semialdehyde dehydrogenase (SSADH) deficiency P51649 (related)
H00552 Glycerol kinase deficiency (GKD) P51843 (related)
H00607 46,XY disorders of sex development (Disorders of gonadal development) P51843 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00259 Apparent mineralocorticoid excess syndrome P80365 (related)
H01257 GABA-transaminase deficiency P80404 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00978 Thrombocytopenia (THC) Q01196 (related)
H01296 Hereditary neuropathy with liability to pressure palsies (HNPP) Q01453 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00523 Noonan syndrome and related disorders Q06124 (related)
H01018 Metachondromatosis Q06124 (related)
H00133 Mucopolysaccharidosis type IX (MPS9) Q12794 (related)
H00421 Mucopolysaccharidosis (MPS) Q12794 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00064 Ataxia telangiectasia (AT) Q13315 (related)
H00094 DNA repair defects Q13315 (related)
H00848 Ataxia with ocular apraxia (AOA) Q13315 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00236 Congenital polycythemia Q9GZT9 (related)

Diseases related to CTD interactions

129 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D003072 Cognition Disorders C00019308
C00000208
D010146 Pain C00000208
D013118 Spinal Cord Diseases C00019308
D048629 Micronuclei, Chromosome-Defective C00031480
D011041 Poisoning C00031480
D008569 Memory Disorders C00002518
D011471 Prostatic Neoplasms C00002518
D008545 Melanoma C00000152
D012220 Rhinitis C00000856
D000138 Acidosis C00000208
D000140 Acidosis, Lactic C00000208
D000544 Alzheimer Disease C00000208
D000550 Amblyopia C00000208
D000749 Anemia, Megaloblastic C00000208
D001161 Arteriosclerosis C00000208
D050197 Atherosclerosis C00000208
D001943 Breast Neoplasms C00000208
D002318 Cardiovascular Diseases C00000208
D002340 Carotid Artery Diseases C00000208
D002386 Cataract C00000208
D002418 Cattle Diseases C00000208
D023341 Chills C00000208
D002779 Cholestasis C00000208
D002780 Cholestasis, Intrahepatic C00000208
D043171 Chromosomal Instability C00000208
D002971 Cleft Lip C00000208
D002972 Cleft Palate C00000208
D003324 Coronary Artery Disease C00000208
D003327 Coronary Disease C00000208
D023921 Coronary Stenosis C00000208
D003693 Delirium C00000208
D003920 Diabetes Mellitus C00000208
D003925 Diabetic Angiopathies C00000208
D004244 Dizziness C00000208
D056486 Drug-Induced Liver Injury C00000208
D064420 Drug-Related Side Effects and Adverse Reactions C00000208
D020820 Dyskinesias C00000208
D050171 Dyslipidemias C00000208
D004415 Dyspepsia C00000208
D004487 Edema C00000208
D019446 Endotoxemia C00000208
D004890 Erythema C00000208
D005076 Exanthema C00000208
D005094 Exophthalmos C00000208
D005128 Eye Diseases C00000208
D005141 Eyelid Diseases C00000208
D005234 Fatty Liver C00000208
D005483 Flushing C00000208
D005767 Gastrointestinal Diseases C00000208
D005923 Glomerulosclerosis, Focal Segmental C00000208
D018149 Glucose Intolerance C00000208
D006073 Gout C00000208
D006501 Hepatic Encephalopathy C00000208
D006505 Hepatitis C00000208
D006937 Hypercholesterolemia C00000208
D006943 Hyperglycemia C00000208
D020138 HYPERHOMOCYSTEINEMIA C00000208
D006950 Hyperlipidemia, Familial Combined C00000208
D006949 Hyperlipidemias C00000208
D006951 Hyperlipoproteinemias C00000208
D006938 Hyperlipoproteinemia Type II C00000208
D006952 Hyperlipoproteinemia Type III C00000208
D006954 Hyperlipoproteinemia Type V C00000208
D006973 Hypertension C00000208
D015228 Hypertriglyceridemia C00000208
D052456 Hypoalphalipoproteinemias C00000208
D007003 Hypoglycemia C00000208
D018476 Hypokinesia C00000208
D007009 Hypolipoproteinemias C00000208
D007022 Hypotension C00000208
D020244 Infarction, Middle Cerebral Artery C00000208
D007249 Inflammation C00000208
D007333 Insulin Resistance C00000208
D002546 Ischemic Attack, Transient C00000208
D007565 Jaundice C00000208
D007634 Keratitis C00000208
D007662 Ketosis C00000208
D007676 Kidney Failure, Chronic C00000208
D007938 Leukemia C00000208
D015470 Leukemia, Myeloid, Acute C00000208
D008060 Lipodystrophy C00000208
D017114 Liver Failure, Acute C00000208
D055370 Lung Injury C00000208
D008269 Macular Edema C00000208
D047508 Massive Hepatic Necrosis C00000208
D024821 Metabolic Syndrome X C00000208
D008881 Migraine Disorders C00000208
D009127 Muscle Rigidity C00000208
D009135 Muscular Diseases C00000208
D009203 Myocardial Infarction C00000208
D017202 Myocardial Ischemia C00000208
D015428 Myocardial Reperfusion Injury C00000208
D009325 Nausea C00000208
D009336 Necrosis C00000208
D009369 Neoplasms C00000208
D009798 Ocular Hypertension C00000208
D002493 Central Nervous System Diseases C00019308
D010292 Paresthesia C00000208
D010383 Pellagra C00000208
D010523 Peripheral Nervous System Diseases C00000208
D010612 Pharyngitis C00000208
D011014 Pneumonia C00000208
D011507 Proteinuria C00000208
D011537 Pruritus C00000208
D012162 Retinal Degeneration C00000208
D012164 Retinal Diseases C00000208
D012817 Signs and Symptoms, Digestive C00000208
D012859 Sjogren's Syndrome C00000208
D012871 Skin Diseases C00000208
D012877 Skin Manifestations C00000208
D016135 Spinal Dysraphism C00000208
D020521 Stroke C00000208
D013575 Syncope C00000208
D018781 Tension-Type Headache C00000208
D014098 Toothache C00000208
D014786 Vision Disorders C00000208
D014839 Vomiting C00000208
D014947 Wounds and Injuries C00000208
D006965 Hyperplasia C00001513
D007680 Kidney Neoplasms C00001513
D009362 Neoplasm Metastasis C00001513
D020163 Ornithine Carbamoyltransferase Deficiency Disease C00001513
D010212 Papilloma C00001513
D011230 Precancerous Conditions C00001513
D014516 Ureteral Neoplasms C00001513
D001749 Urinary Bladder Neoplasms C00001513
D007939 Leukemia L1210 C00003776
D014605 Uveitis C00003776
D003877 Dermatitis, Contact C00000207