Catharanthus roseus

• Index
• Plant Species
• Natural Activity
• Metabolite list (46)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Catharanthus roseus
Genus	Catharanthus
Family	Apocynaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Catharanthus roseus
Linked NCBI taxonomy ID	4058
Linked level	species

Family

Family in NCBI taxonomy	Apocynaceae
ID	4056

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Natural Activity

List (25)

Species	Activity
Catharanthus roseus (L.) G. Don	Analgesic
Catharanthus roseus (L.) G. Don	Antibacterial
Catharanthus roseus (L.) G. Don	Anticancer
Catharanthus roseus (L.) G. Don	Antidiabetic
Catharanthus roseus (L.) G. Don	Antileukemic
Catharanthus roseus (L.) G. Don	Antimitotic
Catharanthus roseus (L.) G. Don	Antipyretic
Catharanthus roseus (L.) G. Don	Antiseptic
Catharanthus roseus (L.) G. Don	CNS Depressant
Catharanthus roseus (L.) G. Don	Collyrium
Catharanthus roseus (L.) G. Don	Depurative
Catharanthus roseus (L.) G. Don	Digitalic
Catharanthus roseus (L.) G. Don	Diuretic
Catharanthus roseus (L.) G. Don	Emetic
Catharanthus roseus (L.) G. Don	Fungicide
Catharanthus roseus (L.) G. Don	Hemostat
Catharanthus roseus (L.) G. Don	Hypoglycemic
Catharanthus roseus (L.) G. Don	Hypotensive
Catharanthus roseus (L.) G. Don	Laxative
Catharanthus roseus (L.) G. Don	Leukopenic
Catharanthus roseus (L.) G. Don	Myorelaxant
Catharanthus roseus (L.) G. Don	Sedative
Catharanthus roseus (L.) G. Don	Teratogenic
Catharanthus roseus (L.) G. Don	Tranquilizer
Catharanthus roseus (L.) G. Don	Vermifuge

Metabolite list (46)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00013985	Syringetin 3-robinobioside / Myricetin 3',5'-dimethyl ether 3-robinobioside / 3-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-galactopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4H-1-benzopyran-4-one					No. 1	No. 15
C00006722	Petunidin 3-glucoside / Petunidin 3-O-beta-D-glucopyranoside	CHEMBL1784264	C455107			No. 2	No. 15
C00006735	Oenin / Malvidin 3-O-beta-D-glucopyranoside	CHEMBL403236	C458419		1 / 0	No. 2	No. 15
C00014876	Hirsutidin 3-glucoside					No. 2	No. 15
C00005206	Mauritianin / 3-O-[2,6-di-O-alpha-L-rhamnopyranosyl-beta-D-galactopyranosyl] kaempferol	CHEMBL362593 CHEMBL1454324 CHEMBL2005346	C069907	1 / 0 / 0		No. 5	No. 15
C00014875	Hirsutidin 3-O-(6-O-p-coumaroyl)glucoside					No. 30	No. 15
C00006896	Petunidin 3-(6''-p-coumarylglucoside)					No. 30	No. 15
C00006903	Malvidin 3-(6''-p-coumarylglucoside)					No. 30	No. 15
C00003088	Loganin	CHEMBL1081584 CHEMBL1081586 CHEMBL1589904 CHEMBL2135791	C059516	2 / 1 / 1	0 / 1	No. 56	No. 36
C00024458	Hazuntine / (-)-Hazuntine / (-)-Lochnerinine					No. 61	No. 4
C00024480	11-Hydroxytabersonine	CHEMBL2011510				No. 61	No. 4
C00024501	19R-Hydroxytabersonine					No. 61	No. 4
C00024481	11-Methoxytabersonine / 16-Methoxytabersonine / (-)-11-Methoxytabersonine	CHEMBL1165751				No. 61	No. 4
C00024457	Lochnericine / (-)-Lochnericine	CHEMBL2011514				No. 61	No. 4
C00024499	Vandrikidine / 19R-Hydroxy-11-methoxy-tabersonine	CHEMBL2011513				No. 61	No. 4
C00024459	(-)-Minovincinine					No. 61	No. 4
C00010604	Loganic acid	CHEMBL1081585 CHEMBL1079678 CHEMBL1356464 CHEMBL1452775	C002947	6 / 8 / 7		No. 64	No. 36
C00000181	Castasterone		C083545			No. 68	No. 11
C00007276	5-alpha-Campestanol					No. 68	No. 11
C00000176	Brassinolide	CHEMBL563853 CHEMBL1801925 CHEMBL1967970	C023623		16 / 2	No. 68	No. 11
C00007273	6-Oxocampestanol					No. 68	No. 11
C00000024	GA24 / Gibberellin A24		C120176			No. 187	No. 41
C00000012	GA12 / Gibberellin A12		C048462			No. 187	No. 41
C00024498	19S-Vindolinine / 19-Epivindolinine / 20-Epivindolinine / 20-epi-Vindolinine	CHEMBL1165590 CHEMBL1330793		15 / 8 / 12		No. 527
C00024462	(-)-Venalstonine					No. 527
C00003098	Secologanin	CHEMBL1235867 CHEMBL1971881	C021086	1 / 0 / 0		No. 806	No. 36
C00000206	Saligel / Salonil / Salicylic acid / 2-Carboxyphenol / o-Hydroxybenzoic acid	CHEMBL424	D020156	124 / 50 / 42	15 / 12	No. 817	No. 81
C00024523	Cathovaline / Cathanneine					No. 1218	No. 4
C00024529	NSC 91993 / Deacetylvindoline / Desacetylvindoline					No. 1218	No. 4
C00024521	Bannucine					No. 1218	No. 4
C00024613	Vindoline / Vindolin / NSC 91994 / (-)-Vindoline	CHEMBL526546 CHEMBL1317962 CHEMBL2001832	C009667	3 / 1 / 1		No. 1218	No. 4
C00024616	NSC 94038 / Vindorosine / Vindorosin / Vindolidin / Vindolidine / (+)-Vindorosine / Demethoxyvindoline					No. 1218	No. 4
C00001122	Glucose / D-Glucose / alpha-D-Glucose	CHEMBL300520 CHEMBL98182 CHEMBL103010 CHEMBL423707 CHEMBL195923 CHEMBL469448 CHEMBL1222152 CHEMBL1222250 CHEMBL1233058 CHEMBL1453070 CHEMBL1519430 CHEMBL1614854 CHEMBL1873035 CHEMBL2093058 CHEMBL2115552		26 / 15 / 15		No. 1283
C00001680	(-)-Akuammicine:Akuammicine	CHEMBL508955				No. 1800	No. 4
C00000207	Benzoic acid	CHEMBL541	D019817	97 / 39 / 33	24 / 1	No. 2192
C00001783	Vincristine	CHEMBL90555 CHEMBL1363013 CHEMBL1396825 CHEMBL1740907 CHEMBL2134016	D014750	129 / 70 / 70	230 / 265	No. 2360	No. 4
C00024497	/ 19-Epivindolinine N-oxide / 20-Epivindolinine N-oxide / 20-Epivindolinine Nb-oxide					No. 2586
C00024615	Vindolinine / 19R-vindolinine / (-)-Vindolinine		C009668			No. 2586
C00024614	Vindolinine N-oxide / Vindolinine Nb-oxide					No. 2586
C00000091	trans-Zeatin	CHEMBL525239	D015026	2 / 3 / 2	0 / 1	No. 2879
C00001386	L-Phenylalanine	CHEMBL25080 CHEMBL301523 CHEMBL379630		27 / 18 / 14		No. 3303
C00000733	Chorismic acid	CHEMBL1160745	D002827			No. 3811
C00000734	Isochorismic acid		C052985			No. 3811
C00024486	14,15-Dehydroepivincadine / (+)-6,7-Dehydroepivincadine / 14,15-Didehydro-epivincadine / 6,7-Didehydro-3-epivincadine					No. 5393
C00007560	Dihydroxyacetone phosphate	CHEMBL1161998	D004099			No. 7554
C00007614	Isochorismate					No. 8480

Human Protein / Gene in interactions

206 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000206 C00000207 C00001386 C00001783 C00024613	0 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000206 C00000207 C00001386 C00001783	1 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000206 C00000207 C00001386 C00001783	0 / 0
P03372	Estrogen receptor	NR3A1	C00000206 C00000207 C00001386 C00001783	1 / 1
O75496	Geminin	Unclassified protein	C00000206 C00001783 C00003088 C00024498	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00000206 C00000207 C00001386 C00001783	0 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000206 C00000207 C00001386 C00001783	1 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000206 C00000207 C00001386 C00001783	0 / 1
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00001386 C00001783 C00010604 C00024498	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00000206 C00000207 C00001386 C00001783	1 / 2
P41143	Delta-type opioid receptor	Opioid receptor	C00000206 C00000207 C00001783	0 / 0
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00000206 C00000207 C00001783	1 / 0
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00000206 C00000207 C00001783	0 / 0
P06239	Tyrosine-protein kinase Lck	Src	C00000206 C00000207 C00001783	0 / 1
P21728	D(1A) dopamine receptor	Dopamine receptor	C00000206 C00000207 C00001783	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000206 C00000207 C00001783	0 / 3
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00000206 C00000207 C00001783	2 / 2
P08246	Neutrophil elastase	S1A	C00000206 C00000207 C00001783	2 / 1
P33765	Adenosine receptor A3	Adenosine receptor	C00000206 C00000207 C00001783	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00000206 C00000207 C00001783	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00000206 C00000207 C00001783	0 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00000206 C00000207 C00001783	5 / 9
P31645	Sodium-dependent serotonin transporter	Serotonin	C00000206 C00000207 C00001783	2 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00000206 C00000207 C00001783	0 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00000206 C00000207 C00001783	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00000206 C00000207 C00001783	1 / 1
P17252	Protein kinase C alpha type	Alpha	C00000206 C00000207 C00001783	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00000206 C00000207 C00001783	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00000206 C00000207 C00001783	2 / 2
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00000206 C00000207 C00001783	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00000206 C00000207 C00001783	0 / 0
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00000206 C00000207 C00001783	0 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00000206 C00000207 C00001783	1 / 1
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00000206 C00000207 C00001783	0 / 0
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00000206 C00000207 C00001783	2 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00000206 C00000207 C00001783	0 / 0
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00000206 C00000207 C00001783	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00000206 C00000207 C00001783	1 / 1
P25101	Endothelin-1 receptor	Endothelin receptor	C00000206 C00000207 C00001783	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00000206 C00000207 C00001783	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00000206 C00000207 C00001783	1 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00000206 C00000207 C00001783	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00000206 C00000207 C00001783	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00000206 C00000207 C00001783	0 / 0
P29466	Caspase-1	C14	C00000206 C00000207 C00001783	0 / 0
P08183	Multidrug resistance protein 1	drug	C00000206 C00001783 C00024613	1 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00000206 C00000207 C00001783	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00000206 C00000207 C00001783	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00000206 C00000207 C00001783	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00000206 C00000207 C00001783	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00000206 C00000207 C00001783	3 / 0
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00000206 C00000207 C00001783	0 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00000206 C00000207 C00001783	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00001122 C00010604 C00024498	1 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00000206 C00000207 C00001783	1 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00000206 C00000207 C00001783	1 / 8
P33032	Melanocortin receptor 5	Melanocortin receptor	C00000206 C00000207 C00001783	0 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00000206 C00000207 C00001783	2 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000206 C00000207 C00001783	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00000206 C00000207 C00001783	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000206 C00000207 C00001783	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00000206 C00000207 C00001783	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00000206 C00000207 C00001783	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00000206 C00000207 C00001783	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00000206 C00000207 C00001783	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00000206 C00000207 C00001783	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00000206 C00000207 C00001783	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00000206 C00000207 C00001783	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00000206 C00000207 C00001783	1 / 1
P35372	Mu-type opioid receptor	Opioid receptor	C00000206 C00000207 C00001783	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00000206 C00000207 C00001783	0 / 0
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00000206 C00000207 C00001783	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00000206 C00000207 C00001783	1 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00000206 C00000207 C00001783	2 / 1
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00000206 C00000207 C00001783	0 / 0
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00000206 C00000207 C00001783	0 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00000206 C00000207 C00001783	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00000206 C00000207 C00001783	1 / 0
P03956	Interstitial collagenase	M10A	C00000206 C00000207 C00001783	0 / 1
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00000206 C00000207 C00001783	1 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00001783 C00010604 C00024498	2 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00000206 C00000207 C00001783	1 / 0
P08311	Cathepsin G	S1A	C00000206 C00000207 C00001783	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00000206 C00000207 C00001783	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00000206 C00000207 C00001783	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00000206 C00000207 C00001783	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00000206 C00000207 C00001783	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00000206 C00000207 C00001783	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00000206 C00000207 C00001783	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00000206 C00000207 C00001783	1 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00000206 C00000207 C00001783	1 / 0
Q92731	Estrogen receptor beta	NR3A2	C00000206 C00000207 C00001783	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00000206 C00000207 C00001783	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00000206 C00000207 C00001783	0 / 0
P25021	Histamine H2 receptor	Histamine receptor	C00000206 C00000207 C00001783	0 / 0
P15121	Aldose reductase	Enzyme	C00000206 C00001122	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00001783 C00024498	1 / 1
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001783 C00024498	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00000206 C00001386	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00000206 C00000207	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00001122 C00024498	1 / 2
O00255	Menin	Unclassified protein	C00001122 C00024498	2 / 5
Q16790	Carbonic anhydrase 9	Lyase	C00000206 C00001386	0 / 1
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00000206 C00001122	0 / 0
O43570	Carbonic anhydrase 12	Lyase	C00000206 C00001386	1 / 2
P01215	Glycoprotein hormones alpha chain	Unclassified protein	C00010604 C00024498	0 / 3
Q9ULX7	Carbonic anhydrase 14	Lyase	C00000206 C00001386	0 / 0
P23280	Carbonic anhydrase 6	Lyase	C00000206 C00001386	0 / 0
P60033	CD81 antigen	Unclassified protein	C00003088 C00010604	1 / 1
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00001783 C00024498	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00001122 C00001783	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00000206 C00024613	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00001122 C00001386	0 / 0
P22748	Carbonic anhydrase 4	Lyase	C00000206 C00001386	1 / 1
P10828	Thyroid hormone receptor beta	NR1A2	C00001122 C00001386	3 / 1
P16473	Thyrotropin receptor	Glycohormone receptor	C00000091 C00000207	3 / 2
P07451	Carbonic anhydrase 3	Lyase	C00000206 C00001386	0 / 0
P43166	Carbonic anhydrase 7	Lyase	C00000206 C00001386	0 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00000206 C00001386	0 / 0
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00000206 C00001386	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00001386 C00001783	2 / 0
P11217	Glycogen phosphorylase, muscle form	Enzyme	C00001122	1 / 1
Q9NPD5	Solute carrier organic anion transporter family member 1B3	Electrochemical transporter	C00001783	1 / 0
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00024498	0 / 0
Q4U2R8	Solute carrier family 22 member 6	Antiporter	C00000206	0 / 0
P11308	Transcriptional regulator ERG	Unclassified protein	C00001122	1 / 2
P05186	Alkaline phosphatase, tissue-nonspecific isozyme	Enzyme	C00001386	3 / 1
P09923	Intestinal-type alkaline phosphatase	Enzyme	C00001386	0 / 0
Q9GZT4	Serine racemase	Enzyme	C00000207	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00024498	0 / 0
P08253	72 kDa type IV collagenase	M10A	C00000206	1 / 3
Q92887	Canalicular multispecific organic anion transporter 1	Unclassified protein	C00001783	1 / 1
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00000206	2 / 2
O15118	Niemann-Pick C1 protein	Unclassified protein	C00024498	1 / 1
P07306	Asialoglycoprotein receptor 1	Membrane receptor	C00001122	0 / 0
P06133	UDP-glucuronosyltransferase 2B4	Enzyme	C00000206	0 / 0
P36537	UDP-glucuronosyltransferase 2B10	Enzyme	C00000206	0 / 0
Q8TCC7	Solute carrier family 22 member 8	Antiporter	C00000206	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00024498	0 / 0
P42858	Huntingtin	Unclassified protein	C00001783	1 / 1
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00001783	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00000206	0 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00001783	0 / 0
O14920	Inhibitor of nuclear factor kappa-B kinase subunit beta	Other serine/threonine protein kinase	C00000206	0 / 0
P05067	Amyloid beta A4 protein	Membrane receptor	C00000206	2 / 2
P11216	Glycogen phosphorylase, brain form	Enzyme	C00001122	0 / 0
P11926	Ornithine decarboxylase	Lyase	C00001783	0 / 0
P11387	DNA topoisomerase 1	Isomerase	C00005206	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00001783	0 / 0
P14920	D-amino-acid oxidase	Enzyme	C00000207	0 / 0
P09382	Galectin-1	Other cytosolic protein	C00001122	0 / 0
P08236	Beta-glucuronidase	Enzyme	C00000206	1 / 2
O75164	Lysine-specific demethylase 4A	Enzyme	C00024498	0 / 0
Q9UQ49	Sialidase-3	Enzyme	C00000207	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00010604	4 / 3
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00000207	0 / 0
P02768	Serum albumin	Secreted protein	C00000206	0 / 0
Q9Y263	Phospholipase A-2-activating protein	Unclassified protein	C00001386	0 / 0
P11226	Mannose-binding protein C	Unclassified protein	C00001122	2 / 2
P02545	Prelamin-A/C	Unclassified protein	C00001783	11 / 10
Q99489	D-aspartate oxidase	Enzyme	C00000207	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00001386	4 / 2
P22894	Neutrophil collagenase	M10A	C00000206	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00000206	0 / 0
Q9NNX6	CD209 antigen	Unclassified protein	C00001122	2 / 0
P08254	Stromelysin-1	M10A	C00000206	1 / 0
P07900	Heat shock protein HSP 90-alpha	Other cytosolic protein	C00003098	0 / 0
Q6P4F1	Alpha-(1,3)-fucosyltransferase 10	Enzyme	C00001122	0 / 0
Q9Y6L6	Solute carrier organic anion transporter family member 1B1	Electrochemical transporter	C00001783	1 / 0
P17931	Galectin-3	Other cytosolic protein	C00001122	0 / 1
Q9UBT6	DNA polymerase kappa	Enzyme	C00001122	0 / 0
Q9UHC3	Acid-sensing ion channel 3	Unclassified protein	C00000206	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00000206	4 / 1
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00000091	0 / 0
P40225	Thrombopoietin	Unclassified protein	C00001783	1 / 1
P04637	Cellular tumor antigen p53	Transcription Factor	C00001783	7 / 37
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00001122	1 / 1
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00000206	0 / 0
P33527	Multidrug resistance-associated protein 1	drugs	C00001783	0 / 0
P10323	Acrosin	S1A	C00001122	0 / 0
Q96QA9	Multidrug resistance associated protein	Unclassified protein	C00001783	0 / 0
Q9NSA0	Solute carrier family 22 member 11	Transporter	C00000206	0 / 0
Q5T3U5	Multidrug resistance-associated protein 7	Unclassified protein	C00001783	0 / 0
Q05BR4	SLC16A10 protein	Unclassified protein	C00001386	0 / 0
Q13748	Tubulin alpha-3C/D chain	Structural	C00001783	0 / 0
P68366	Tubulin alpha-4A chain	Structural	C00001783	0 / 0
Q9H4B7	Tubulin beta-1 chain	Structural	C00001783	1 / 0
P04350	Tubulin beta-4A chain	Structural	C00001783	2 / 0
Q3ZCM7	Tubulin beta-8 chain	Structural	C00001783	0 / 0
P07437	Tubulin beta chain	Structural	C00001783	0 / 0
Q71U36	Tubulin alpha-1A chain	Structural	C00001783	1 / 1
P68371	Tubulin beta-4B chain	Structural	C00001783	0 / 0
Q13509	Tubulin beta-3 chain	Structural	C00001783	2 / 1
P42345	Serine/threonine-protein kinase mTOR	Enzyme	C00001783	0 / 0
Q9UJ71	C-type lectin domain family 4 member K	Unclassified protein	C00001122	1 / 0
P22897	Macrophage mannose receptor 1	Unclassified protein	C00001122	0 / 0
Q8WTT0	C-type lectin domain family 4 member C	Unclassified protein	C00001122	0 / 0
Q6EIG7	C-type lectin domain family 6 member A	Unclassified protein	C00001122	0 / 0
P35247	Pulmonary surfactant-associated protein D	Unclassified protein	C00001122	0 / 0
Q9H2X3	C-type lectin domain family 4 member M	Unclassified protein	C00001122	0 / 0
P68363	Tubulin alpha-1B chain	Unclassified protein	C00001783	0 / 0
Q13885	Tubulin beta-2A chain	Structural	C00001783	0 / 0
Q6PEY2	Tubulin alpha-3E chain	Unclassified protein	C00001783	0 / 0
Q9BQE3	Tubulin alpha-1C chain	Unclassified protein	C00001783	0 / 0
Q9BUF5	Tubulin beta-6 chain	Structural	C00001783	0 / 0
Q9BVA1	Tubulin beta-2B chain	Structural	C00001783	1 / 0

275 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000176 C00001783
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00000176 C00001783
7295	TXN, TRDX, TRX, TRX1	thioredoxin	C00000206 C00000207
4489	MT1A, MT1, MT1S, MTC	metallothionein 1A	C00000206 C00000207
891	CCNB1, CCNB	cyclin B1	C00000176 C00001783
8644	AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS	aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357)	C00000206 C00000207
1645	AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB	aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112)	C00000206 C00000207
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00000207 C00001783
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00000207 C00001783
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000176 C00001783
4193	MDM2, ACTFS, HDMX, hdm2	MDM2 oncogene, E3 ubiquitin protein ligase	C00000176 C00001783
51646	YPEL5	yippee-like 5 (Drosophila)	C00001783
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00000176
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00000176
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00000176
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00000176
8654	PDE5A, CGB-PDE, CN5A, PDE5	phosphodiesterase 5A, cGMP-specific (EC:3.1.4.35)	C00006735
19	ABCA1, ABC-1, ABC1, CERP, HDLDT1, TGD	ATP-binding cassette, sub-family A (ABC1), member 1	C00001783
26154	ABCA12, ARCI4A, ARCI4B, ICR2B, LI2	ATP-binding cassette, sub-family A (ABC1), member 12	C00001783
24	ABCA4, ABC10, ABCR, ARMD2, CORD3, FFM, RMP, RP19, STGD, STGD1	ATP-binding cassette, sub-family A (ABC1), member 4	C00001783
23461	ABCA5, ABC13, EST90625	ATP-binding cassette, sub-family A (ABC1), member 5	C00001783
10351	ABCA8	ATP-binding cassette, sub-family A (ABC1), member 8	C00001783
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00001783
8647	ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP	ATP-binding cassette, sub-family B (MDR/TAP), member 11	C00001783
5244	ABCB4, ABC21, GBD1, ICP3, MDR2, MDR2/3, MDR3, PFIC-3, PGY3	ATP-binding cassette, sub-family B (MDR/TAP), member 4 (EC:3.6.3.44)	C00001783
10058	ABCB6, ABC, ABC14, DUH3, LAN, MCOPCB7, MTABC3, PRP, umat	ATP-binding cassette, sub-family B (MDR/TAP), member 6	C00001783
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00001783
89845	ABCC10, EST182763, MRP7, SIMRP7	ATP-binding cassette, sub-family C (CFTR/MRP), member 10	C00001783
1244	ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	C00001783
8714	ABCC3, ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	C00001783
10257	ABCC4, EST170205, MOAT-B, MOATB, MRP4	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	C00001783
10057	ABCC5, ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	C00001783
368	ABCC6, ABC34, ARA, EST349056, GACI2, MLP1, MOAT-E, MOATE, MRP6, PXE, PXE1, URG7	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	C00001783
5825	ABCD3, ABC43, PMP70, PXMP1, ZWS2	ATP-binding cassette, sub-family D (ALD), member 3	C00001783
9619	ABCG1, ABC8, WHITE1	ATP-binding cassette, sub-family G (WHITE), member 1	C00001783
9429	ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1	ATP-binding cassette, sub-family G (WHITE), member 2	C00001783
64137	ABCG4, WHITE2	ATP-binding cassette, sub-family G (WHITE), member 4	C00001783
81569	ACTL8, CT57	actin-like 8	C00001783
154	ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR	adrenoceptor beta 2, surface	C00001783
57379	AICDA, AID, ARP2, CDA2, HIGM2	activation-induced cytidine deaminase (EC:3.5.4.38)	C00001783
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00001783
216	ALDH1A1, ALDC, ALDH-E1, ALDH1, ALDH11, PUMB1, RALDH1	aldehyde dehydrogenase 1 family, member A1 (EC:1.2.1.36)	C00001783
410	ARSA, MLD	arylsulfatase A (EC:3.1.6.8)	C00001783
259266	ASPM, ASP, Calmbp1, MCPH5	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	C00001783
538	ATP7A, DSMAX, MK, MNK, SMAX3	ATPase, Cu++ transporting, alpha polypeptide (EC:3.6.3.54)	C00001783
540	ATP7B, PWD, WC1, WD, WND	ATPase, Cu++ transporting, beta polypeptide (EC:3.6.3.54)	C00001783
6790	AURKA, AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7	aurora kinase A (EC:2.7.11.1)	C00001783
551	AVP, ADH, ARVP, AVP-NPII, AVRP, VP	arginine vasopressin	C00001783
578	BAK1, BAK, BAK-LIKE, BCL2L7, CDN1	BCL2-antagonist/killer 1	C00001783
581	BAX, BCL2L4	BCL2-associated X protein	C00001783
672	BRCA1, BRCAI, BRCC1, BROVCA1, IRIS, PNCA4, PPP1R53, PSCP, RNF53	breast cancer 1, early onset	C00001783
675	BRCA2, BRCC2, BROVCA2, FACD, FAD, FAD1, FANCB, FANCD, FANCD1, GLM3, PNCA2	breast cancer 2, early onset	C00001783
100170841	C17orf96	chromosome 17 open reading frame 96	C00001783
8618	CADPS, CADPS1, CAPS, CAPS1	Ca++-dependent secretion activator	C00001783
84254	CAMKK1, CAMKKA	calcium/calmodulin-dependent protein kinase kinase 1, alpha (EC:2.7.11.17)	C00001783
57082	CASC5, AF15Q14, CT29, D40, KNL1, PPP1R55, Spc7, hKNL-1, hSpc105	cancer susceptibility candidate 5	C00001783
839	CASP6, MCH2	caspase 6, apoptosis-related cysteine peptidase (EC:3.4.22.59)	C00001783
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00001783
847	CAT	catalase (EC:1.11.1.6)	C00001783
890	CCNA2, CCN1, CCNA	cyclin A2	C00001783
960	CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1	CD44 molecule (Indian blood group)	C00001783
157313	CDCA2, Repo-Man	cell division cycle associated 2	C00001783
1020	CDK5, PSSALRE	cyclin-dependent kinase 5 (EC:2.7.11.22)	C00001783
1022	CDK7, CAK1, CDKN7, HCAK, MO15, STK1, p39MO15	cyclin-dependent kinase 7 (EC:2.7.11.23 2.7.11.22)	C00001783
1029	CDKN2A, ARF, CDK4I, CDKN2, CMM2, INK4, INK4A, MLM, MTS-1, MTS1, P14, P14ARF, P16, P16-INK4A, P16INK4, P16INK4A, P19, P19ARF, TP16	cyclin-dependent kinase inhibitor 2A	C00001783
1051	CEBPB, C/EBP-beta, CRP2, IL6DBP, LAP, LIP, NF-IL6, TCF5	CCAAT/enhancer binding protein (C/EBP), beta	C00001783
11190	CEP250, C-NAP1, CEP2, CNAP1	centrosomal protein 250kDa	C00001783
23563	CHST5, I-GlcNAc-6-ST, I-GlcNAc6ST, glcNAc6ST-3, gn6st-3, hIGn6ST	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5	C00001783
57019	CIAPIN1, 2810413N20Rik, Anamorsin, DRE2, PRO0915	cytokine induced apoptosis inhibitor 1	C00001783
23242	COBL	cordon-bleu WH2 repeat protein	C00001783
1299	COL9A3, DJ885L7.4.1, EDM3, IDD, MED	collagen, type IX, alpha 3	C00001783
1396	CRIP1, CRHP, CRIP, CRP-1, CRP1	cysteine-rich protein 1 (intestinal)	C00001783
1499	CTNNB1, CTNNB, MRD19, armadillo	catenin (cadherin-associated protein), beta 1, 88kDa	C00001783
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00001783
1558	CYP2C8, CPC8, CYPIIC8, MP-12/MP-20	cytochrome P450, family 2, subfamily C, polypeptide 8 (EC:1.14.14.1)	C00001783
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00001783
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00001783
1577	CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3	cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1)	C00001783
1582	CYP8B1, CP8B, CYP12	cytochrome P450, family 8, subfamily B, polypeptide 1 (EC:1.14.13.95)	C00001783
1617	DAZ1, DAZ, SPGY	deleted in azoospermia 1	C00001783
57054	DAZ3, pDP1679	deleted in azoospermia 3	C00001783
57135	DAZ4, pDP1680, pDP1681	deleted in azoospermia 4	C00001783
11056	DDX52, HUSSY19, ROK1	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 (EC:3.6.4.13)	C00001783
9046	DOK2, p56DOK, p56dok-2	docking protein 2, 56kDa	C00001783
1806	DPYD, DHP, DHPDHASE, DPD	dihydropyrimidine dehydrogenase (EC:1.3.1.2)	C00001783
1958	EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225	early growth response 1	C00001783
79071	ELOVL6, FACE, FAE, LCE	ELOVL fatty acid elongase 6 (EC:2.3.1.199)	C00001783
2052	EPHX1, EPHX, EPOX, HYL1, MEH	epoxide hydrolase 1, microsomal (xenobiotic) (EC:3.3.2.9)	C00001783
2064	ERBB2, CD340, HER-2, HER-2/neu, HER2, MLN_19, NEU, NGL, TKR1	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1)	C00001783
2068	ERCC2, COFS2, EM9, TTD, XPD	excision repair cross-complementing rodent repair deficiency, complementation group 2 (EC:3.6.4.12)	C00001783
9156	EXO1, HEX1, hExoI	exonuclease 1	C00001783
2147	F2, PT, RPRGL2, THPH1	coagulation factor II (thrombin) (EC:3.4.21.5)	C00001783
2152	F3, CD142, TF, TFA	coagulation factor III (thromboplastin, tissue factor)	C00001783
84668	FAM126A, DRCTNNB1A, HCC, HLD5, HYCC1	family with sequence similarity 126, member A	C00001783
55215	FANCI, KIAA1794	Fanconi anemia, complementation group I	C00001783
356	FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6	Fas ligand (TNF superfamily, member 6)	C00001783
9103	FCGR2C, CD32, CD32C, CDW32, FCG2, FCRIIC, IGFR2	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	C00001783
2264	FGFR4, CD334, JTK2, TKF	fibroblast growth factor receptor 4 (EC:2.7.10.1)	C00001783
9896	FIG4, ALS11, CMT4J, KIAA0274, SAC3, YVS, dJ249I4.1	FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)	C00001783
2528	FUT6, FCT3A, FT1A, Fuc-TVI, FucT-VI	fucosyltransferase 6 (alpha (1,3) fucosyltransferase) (EC:2.4.1.65)	C00001783
26748	GAGE12I, AL4, CT4.7, GAGE-7B, GAGE7B	G antigen 12I	C00001783
2574	GAGE2C, CT4.2, GAGE-2, GAGE-2C, GAGE2	G antigen 2C	C00001783
2575			C00001783
2576	GAGE4, CT4.4	G antigen 4	C00001783
2578	GAGE6, CT4.6	G antigen 6	C00001783
2579	GAGE7, AL4, CT4.7, GAGE-7	G antigen 7	C00001783
1019	CDK4, CMM3, PSK-J3	cyclin-dependent kinase 4 (EC:2.7.11.22)	C00000176
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00000176
51608	GET4, C7orf20, CEE, TRC35	golgi to ER traffic protein 4 homolog (S. cerevisiae)	C00001783
2690	GHR, GHBP	growth hormone receptor	C00001783
2735	GLI1, GLI	GLI family zinc finger 1	C00001783
2838	GPR15, BOB	G protein-coupled receptor 15	C00001783
2876	GPX1, GPXD, GSHPX1	glutathione peroxidase 1 (EC:1.11.1.9)	C00001783
2944	GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1	glutathione S-transferase mu 1 (EC:2.5.1.18)	C00001783
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00001783
2954	GSTZ1, GSTZ1-1, MAAI, MAI	glutathione S-transferase zeta 1 (EC:2.5.1.18 5.2.1.2)	C00001783
2965	GTF2H1, BTF2, P62, TFB1, TFIIH	general transcription factor IIH, polypeptide 1, 62kDa	C00001783
3044	HBBP1	hemoglobin, beta pseudogene 1	C00001783
113510	HELQ, HEL308	helicase, POLQ-like (EC:3.6.4.12)	C00001783
9709	HERPUD1, HERP, Mif1, SUP	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	C00001783
3161	HMMR, CD168, IHABP, RHAMM	hyaluronan-mediated motility receptor (RHAMM)	C00001783
3265	HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1	Harvey rat sarcoma viral oncogene homolog	C00001783
3316	HSPB2, HSP27, Hs.78846, LOH11CR1K, MKBP	heat shock 27kDa protein 2	C00001783
3399	ID3, HEIR-1, bHLHb25	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	C00001783
10561	IFI44, MTAP44, TLDC5, p44	interferon-induced protein 44	C00001783
3439	IFNA1, IFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA13, IFNA@	interferon, alpha 1	C00001783
3479	IGF1, IGF-I, IGF1A, IGFI	insulin-like growth factor 1 (somatomedin C)	C00001783
10643	IGF2BP3, CT98, IMP-3, IMP3, KOC1, VICKZ3	insulin-like growth factor 2 mRNA binding protein 3	C00001783
3500			C00001783
3508	IGHMBP2, CATF1, HCSA, HMN6, SMARD1, SMUBP2, ZFAND7	immunoglobulin mu binding protein 2 (EC:3.6.4.13 3.6.4.12)	C00001783
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00001783
9118	INA, NEF5, NF-66, TXBP-1	internexin neuronal intermediate filament protein, alpha	C00001783
9452	ITM2A, BRICD2A, E25A	integral membrane protein 2A	C00001783
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00001783
3741	KCNA5, ATFB7, HCK1, HK2, HPCN1, KV1.5, PCN1	potassium voltage-gated channel, shaker-related subfamily, member 5	C00001783
9757	KMT2B, HRX2, MLL1B, MLL2, MLL4, TRX2, WBP7	lysine (K)-specific methyltransferase 2B (EC:2.1.1.43)	C00001783
3904	LAIR2, CD306	leukocyte-associated immunoglobulin-like receptor 2	C00001783
10859	LILRB1, CD85J, ILT-2, ILT2, LIR-1, LIR1, MIR-7, MIR7	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	C00001783
11006	LILRB4, CD85K, ILT-3, ILT3, LIR-5, LIR5	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	C00001783
4041	LRP5, BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2	low density lipoprotein receptor-related protein 5	C00001783
4049	LTA, LT, TNFB, TNFSF1	lymphotoxin alpha	C00001783
4101	MAGEA2, CT1.2, MAGE2, MAGEA2A	melanoma antigen family A, 2	C00001783
266740	MAGEA2B, MAGE2, MAGEA2	melanoma antigen family A, 2B	C00001783
23005	MAPKBP1, JNKBP-1	mitogen-activated protein kinase binding protein 1	C00001783
22919	MAPRE1, EB1	microtubule-associated protein, RP/EB family, member 1	C00001783
22924	MAPRE3, EB3, EBF3, EBF3-S, RP3	microtubule-associated protein, RP/EB family, member 3	C00001783
4153	MBL2, COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD	mannose-binding lectin (protein C) 2, soluble	C00001783
54842	MFSD6, MMR2, hMMR2	major facilitator superfamily domain containing 6	C00001783
4255	MGMT	O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63)	C00001783
440823	MIAT, C22orf35, GOMAFU, LINC00066, NCRNA00066, RNCR2	myocardial infarction associated transcript (non-protein coding)	C00001783
574456	MIR497, MIRN497, hsa-mir-497	microRNA 497	C00001783
4288	MKI67, KIA, MIB-1	marker of proliferation Ki-67	C00001783
4548	MTR, HMAG, MS, cblG	5-methyltetrahydrofolate-homocysteine methyltransferase (EC:2.1.1.13)	C00001783
4595	MUTYH, CYP2C, MYH	mutY homolog (EC:3.2.2.-)	C00001783
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00001783
4613	MYCN, MODED, MYCNOT, N-myc, NMYC, ODED, bHLHe37	v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog	C00001783
53904	MYO3A, DFNB30	myosin IIIA (EC:2.7.11.1)	C00001783
9	NAT1, AAC1, MNAT, NAT-1, NATI	N-acetyltransferase 1 (arylamine N-acetyltransferase) (EC:2.3.1.5)	C00001783
4773	NFATC2, NFAT1, NFATP	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	C00001783
10577	NPC2, EDDM1, HE1	Niemann-Pick disease, type C2	C00001783
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00001783
8829	NRP1, BDCA4, CD304, NP1, NRP, VEGF165R	neuropilin 1	C00001783
114880	OSBPL6, ORP6	oxysterol binding protein-like 6	C00001783
55644	OSGEP, GCPL1, KAE1, OSGEP1, PRSMG1	O-sialoglycoprotein endopeptidase (EC:3.4.24.57)	C00001783
8712	PAGE1, AL5, CT16.3, GAGE-9, GAGEB1, PAGE-1	P antigen family, member 1 (prostate associated)	C00001783
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00001783
23178	PASK, PASKIN, STK37	PAS domain containing serine/threonine kinase (EC:2.7.11.1)	C00001783
301164			C00001783
25894	PLEKHG4, ARHGEF44, PRTPHN1, SCA4	pleckstrin homology domain containing, family G (with RhoGef domain) member 4	C00001783
84898	PLXDC2, TEM7R	plexin domain containing 2	C00001783
5376	PMP22, CMT1A, CMT1E, DSS, GAS-3, HMSNIA, HNPP, Sp110	peripheral myelin protein 22	C00001783
5423	POLB	polymerase (DNA directed), beta (EC:2.7.7.7)	C00001783
5428	POLG, MDP1, MIRAS, MTDPS4A, MTDPS4B, PEO, POLG1, POLGA, SANDO, SCAE	polymerase (DNA directed), gamma (EC:2.7.7.7)	C00001783
5445	PON2	paraoxonase 2 (EC:3.1.1.2 3.1.1.81)	C00001783
5467	PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB	peroxisome proliferator-activated receptor delta	C00001783
84152	PPP1R1B, DARPP-32, DARPP32	protein phosphatase 1, regulatory (inhibitor) subunit 1B (EC:3.1.3.16)	C00001783
9055	PRC1, ASE1	protein regulator of cytokinesis 1	C00001783
5621	PRNP, ASCR, AltPrP, CD230, CJD, GSS, KURU, PRIP, PrP, PrP27-30, PrP33-35C, PrPc, p27-30	prion protein	C00001783
57716	PRX, CMT4F	periaxin	C00001783
5695	PSMB7, Z	proteasome (prosome, macropain) subunit, beta type, 7 (EC:3.4.25.1)	C00001783
5740	PTGIS, CYP8, CYP8A1, PGIS, PTGI	prostaglandin I2 (prostacyclin) synthase (EC:5.3.99.4)	C00001783
5742	PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00001783
2185	PTK2B, CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK	protein tyrosine kinase 2 beta (EC:2.7.10.2)	C00001783
5783	PTPN13, FAP-1, PNP1, PTP-BAS, PTP-BL, PTP1E, PTPL1, PTPLE, hPTP1E	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) (EC:3.1.3.48)	C00001783
54870	QRICH1	glutamine-rich 1	C00001783
84991	RBM17, SPF45	RNA binding motif protein 17	C00001783
159162	RBMY2FP	RNA binding motif protein, Y-linked, family 2, member F pseudogene	C00001783
6001	RGS10	regulator of G-protein signaling 10	C00001783
26575	RGS17, RGS-17, RGSZ2, hRGS17	regulator of G-protein signaling 17	C00001783
6095	RORA, NR1F1, ROR1, ROR2, ROR3, RZR-ALPHA, RZRA	RAR-related orphan receptor A	C00001783
6128	RPL6, L6, SHUJUN-2, TAXREB107, TXREB1	ribosomal protein L6	C00001783
6240	RRM1, R1, RIR1, RR1	ribonucleotide reductase M1 (EC:1.17.4.1)	C00001783
864	RUNX3, AML2, CBFA3, PEBP2aC	runt-related transcription factor 3	C00001783
949	SCARB1, CD36L1, CLA-1, CLA1, HDLQTL6, SR-BI, SRB1	scavenger receptor class B, member 1	C00001783
6401	SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2	selectin E	C00001783
5055	SERPINB2, HsT1201, PAI, PAI-2, PAI2, PLANH2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	C00001783
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00001783
6442	SGCA, 50-DAG, A2, ADL, DAG2, DMDA2, LGMD2D, SCARMD1, adhalin	sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)	C00001783
7979	SHFM1, DSS1, ECD, SEM1, SHFD1, SHSF1, Shfdg1	split hand/foot malformation (ectrodactyly) type 1	C00001783
6492	SIM1, bHLHe14	single-minded family bHLH transcription factor 1	C00001783
6555	SLC10A2, ASBT, IBAT, ISBT, NTCP2, PBAM	solute carrier family 10 (sodium/bile acid cotransporter), member 2	C00001783
9990	SLC12A6, ACCPN, KCC3, KCC3A, KCC3B	solute carrier family 12 (potassium/chloride transporter), member 6	C00001783
6584	SLC22A5, CDSP, OCTN2, OCTN2VT	solute carrier family 22 (organic cation/carnitine transporter), member 5	C00001783
9154	SLC28A1, CNT1, HCNT1	solute carrier family 28 (concentrative nucleoside transporter), member 1	C00001783
6513	SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED	solute carrier family 2 (facilitated glucose transporter), member 1	C00001783
28232	SLCO3A1, OATP-D, OATP3A1, OATPD, SLC21A11	solute carrier organic anion transporter family, member 3A1	C00001783
10592	SMC2, CAP-E, CAPE, SMC-2, SMC2L1	structural maintenance of chromosomes 2	C00001783
6649	SOD3, EC-SOD	superoxide dismutase 3, extracellular (EC:1.15.1.1)	C00001783
6654	SOS1, GF1, GGF1, GINGF, HGF, NS4	son of sevenless homolog 1 (Drosophila)	C00001783
54908	SPDL1, CCDC99	spindle apparatus coiled-coil protein 1	C00001783
6716	SRD5A2	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (EC:1.3.1.22)	C00001783
6717	SRI, CP-22, CP22, SCN, V19	sorcin	C00001783
6756	SSX1, CT5.1, SSRC	synovial sarcoma, X breakpoint 1	C00001783
6757	SSX2, CT5.2, CT5.2A, HD21, HOM-MEL-40, SSX	synovial sarcoma, X breakpoint 2	C00001783
6759	SSX4, CT5.4	synovial sarcoma, X breakpoint 4	C00001783
548313	SSX4B, CT5.4	synovial sarcoma, X breakpoint 4B	C00001783
6772	STAT1, CANDF7, ISGF-3, STAT91	signal transducer and activator of transcription 1, 91kDa	C00001783
6820	SULT2B1, HSST2	sulfotransferase family, cytosolic, 2B, member 1 (EC:2.8.2.2)	C00001783
55530	SVOP	SV2 related protein homolog (rat)	C00001783
10732	TCFL5, CHA, E2BP-1, Figlb, bHLHe82	transcription factor-like 5 (basic helix-loop-helix)	C00001783
83660	TLN2, ILWEQ	talin 2	C00001783
50999	TMED5, CGI-100, p28	transmembrane emp24 protein transport domain containing 5	C00001783
26022	TMEM98	transmembrane protein 98	C00001783
944	TNFSF8, CD153, CD30L, CD30LG	tumor necrosis factor (ligand) superfamily, member 8	C00001783
7167	TPI1, TIM, TPI, TPID	triosephosphate isomerase 1 (EC:5.3.1.1)	C00001783
7173	TPO, MSA, TDH2A, TPX	thyroid peroxidase (EC:1.11.1.8)	C00001783
1200	TPP1, CLN2, LPIC, TPP-1	tripeptidyl peptidase I (EC:3.4.14.9)	C00001783
7223	TRPC4, HTRP-4, HTRP4, TRP4	transient receptor potential cation channel, subfamily C, member 4	C00001783
7251	TSG101, TSG10, VPS23	tumor susceptibility 101	C00001783
706	TSPO, BPBS, BZRP, DBI, IBP, MBR, PBR, PBS, PKBS, PTBR, mDRC, pk18	translocator protein (18kDa)	C00001783
1890	TYMP, ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF	thymidine phosphorylase (EC:2.4.2.4)	C00001783
7298	TYMS, HST422, TMS, TS	thymidylate synthetase (EC:2.1.1.45)	C00001783
7350	UCP1, SLC25A7, UCP	uncoupling protein 1 (mitochondrial, proton carrier)	C00001783
7364	UGT2B7, UDPGT_2B9, UDPGT2B7, UDPGTH2, UGT2B9	UDP glucuronosyltransferase 2 family, polypeptide B7 (EC:2.4.1.17)	C00001783
440279	UNC13C	unc-13 homolog C (C. elegans)	C00001783
7380	UPK3A, UP3A, UPIII, UPIIIA, UPK3	uroplakin 3A	C00001783
27340	UTP20, DRIM	UTP20, small subunit (SSU) processome component, homolog (yeast)	C00001783
7421	VDR, NR1I1	vitamin D (1,25- dihydroxyvitamin D3) receptor	C00001783
7481	WNT11, HWNT11	wingless-type MMTV integration site family, member 11	C00001783
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00000176
169270	ZNF596	zinc finger protein 596 (EC:2.1.1.43)	C00001783
30834	ZNRD1, HTEX-6, Rpa12, TEX6, ZR14, hZR14, tctex-6	zinc ribbon domain containing 1 (EC:2.7.7.6)	C00001783
231	AKR1B1, ADR, ALDR1, ALR2, AR	aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21)	C00000207
57016	AKR1B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI	aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2)	C00000207
898	CCNE1, CCNE	cyclin E1	C00000176
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00000176
2235	FECH, EPP, FCE	ferrochelatase (EC:4.99.1.1)	C00000207
2512	FTL, NBIA3	ferritin, light polypeptide	C00000207
2539	G6PD, G6PD1	glucose-6-phosphate dehydrogenase (EC:1.1.1.49)	C00000207
2936	GSR	glutathione reductase (EC:1.8.1.7)	C00000207
2938	GSTA1, GST2, GSTA1-1, GTH1	glutathione S-transferase alpha 1 (EC:2.5.1.18)	C00000207
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00000207
4097	MAFG, hMAF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G	C00000207
4199	ME1, HUMNDME, MES	malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40)	C00000207
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000176
4502	MT2A, MT2	metallothionein 2A	C00000207
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00000207
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00000207
5226	PGD, 6PGD	phosphogluconate dehydrogenase (EC:1.1.1.44)	C00000207
22949	PTGR1, LTB4DH, PGR1, ZADH3	prostaglandin reductase 1 (EC:1.3.1.48 1.3.1.74)	C00000207
6566	SLC16A1, HHF7, MCT, MCT1	solute carrier family 16 (monocarboxylate transporter), member 1	C00000207
140809	SRXN1, C20orf139, Npn3, SRX, SRX1	sulfiredoxin 1 (EC:1.8.98.2)	C00000207
637	BID, FP497	BH3 interacting domain death agonist	C00000176
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00000207
1646	AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8	aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357)	C00000206
3565	IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4	interleukin 4	C00000206
23764	MAFF, U-MAF, hMafF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F	C00000206
55867	SLC22A11, OAT4, hOAT4	solute carrier family 22 (organic anion/urate transporter), member 11	C00000206
9356	SLC22A6, HOAT1, OAT1, PAHT, ROAT1	solute carrier family 22 (organic anion transporter), member 6	C00000206
10864	SLC22A7, NLT, OAT2	solute carrier family 22 (organic anion transporter), member 7	C00000206
114571	SLC22A9, HOAT4, OAT4, OAT7, UST3H, ust3	solute carrier family 22 (organic anion transporter), member 9	C00000206
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00000206
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00000206
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00000206
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00000206

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Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions