KCF-S cluster No. 68 (63 metabolites)

Corresponding Phytochemical cluster No. 11

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (63)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	82
asterids	34
Liliopsida	15
Spermatophyta	12
eudicotyledons	8
Euphyllophyta	6
Viridiplantae	2
Magnoliophyta	1

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Cumulative family count (Top 20)

class name	count
Fabaceae	38
Brassicaceae	36
Rubiaceae	15
Poaceae	12
Pinaceae	9
Apocynaceae	6
Theaceae	6
Equisetaceae	4
Hamamelidaceae	4
Asteraceae	3
Cupressaceae	3
Fagaceae	3
Hydrodictyaceae	2
Ophidiasteridae	2
Convolvulaceae	2
Caryophyllaceae	2
Betulaceae	2
Polygonaceae	2
Solanaceae	2
Physaraceae	2

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Ergostane	6

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metabolites link (6)

br08003 Category	KEGG ID	KNApSAcK ID
Ergostane	C08814	C00000176
Ergostane	C11049	C00000180
Ergostane	C15794	C00000181
Ergostane	C15793	C00000185
Ergostane	C15789	C00007273
Ergostane	C15790	C00007275

Metabolite list (63)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00000176	Brassinolide	CHEMBL563853 CHEMBL1801925 CHEMBL1967970	C023623		16 / 2
C00000177	Dolicholide
C00000178	28-Homodolicholide
C00000180	24-Epibrassinolide	CHEMBL563853 CHEMBL1801925 CHEMBL1967970
C00000181	Castasterone		C083545
C00000185	Typhasterol / 2-Deoxycastasterone
C00000186	Teasterone
C00000187	24-epi-Castasterone
C00000188	3,24-Diepicastasterone
C00000189	Brassinone / Norcastasterone / 28-Norcastasterone
C00000190	28-Homocastasterone / 24-S-24-Ethylbrassinone	CHEMBL488432 CHEMBL1801920	C070164		14 / 1
C00000191	2-Deoxy-28-homocastasterone
C00000192	Dolichosterone
C00000193	Homodolichosterone / 28-Homodolichosterone / 28-Methyldolichosterone
C00000194	25-Methyldolichosterone
C00000195	2-epi-25-Methyldolichosterone / 25-Methyl-2-epidolichosterone / 25-Methyl-2-epi-dolichosterone
C00000196	2,3-diepi-25-Methyldolichosterone
C00000197	2-Deoxy-25-Methyldolichosterone
C00000198	3-epi-2-Deoxy-25-methyldolichosterone
C00000199	6-Deoxocastasterone
C00000200	3-epi-6-Deoxocastasterone
C00000201	6-Deoxodolichosterone
C00000202	6-Deoxo-28-homo-dolichosterone
C00000203	6-Deoxo-25-methyldolichosterone
C00007262	3-Dehydroteasterone
C00007273	6-Oxocampestanol
C00007274	3-Dehydro-6-deoxoteasterone
C00007275	Cathasterone
C00007276	5-alpha-Campestanol
C00007277	6-Deoxocathasterone
C00007278	6-Deoxotyphasterol
C00007334	24-Epiteasterone
C00007335	24-Epityphasterol
C00007515	(5alpha,24R)-Ergostan-3-one
C00007516	Ergostanol / Campestanol / (24S)24-Methylcholestan-3beta-ol		C003535
C00007517	6alpha-Hydroxycampestanol
C00007520	(22S,24R)-22-Hydroxy-5alpha-ergostan-3-one
C00007521	6-Deoxoteasterone
C00007522	6-Dihydrocastasterone
C00007528	28-Homobrassinolide	CHEMBL1801919 CHEMBL1801924
C00007529	28-Norbrassinolide
C00007617	(24R)-24-Methyl-5-alpha-cholestan-3-one
C00031395	Stigmastane-3,6-dione
C00031572	Agavegenin D / (-)-Agavegenin D
C00032163	Sitostanol / Stigmastanol / beta-Sitostanol	CHEMBL305498 CHEMBL252364	C021255
C00032164	Sitostanyl formate / (-)-Sitostanyl formate
C00036251	2,3-Diepicastasterone
C00036254	23-Dehydrobrassinolide
C00036256	24-epi-Secasterone
C00036257	25-Methylcastasterone
C00036258	28-Homoteasterone
C00036259	28-Homotyphasterol
C00036260	28-Nortyphasterol
C00036261	2-Epicastasterone
C00036543	3-Epicastasterone
C00036612	6-Deoxo-24-epicastasterone
C00037797	Secasterone
C00038287	5alpha-Stigmastnae-3beta,5,6beta-triol
C00041127	Stigmastan 3,6-dione
C00041128	Stigmastan-3-one
C00042080	24xi-Methylcholestanol
C00043373	Certonardosterol D3	CHEMBL463078 CHEMBL464938
C00043376	Certonardosterol E2	CHEMBL463078 CHEMBL464938

Human Protein / Gene in interactions

16 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000176 C00000190
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00000176 C00000190
637	BID, FP497	BH3 interacting domain death agonist	C00000176 C00000190
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000176 C00000190
891	CCNB1, CCNB	cyclin B1	C00000176 C00000190
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000176 C00000190
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00000176 C00000190
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00000176 C00000190
4193	MDM2, ACTFS, HDMX, hdm2	MDM2 oncogene, E3 ubiquitin protein ligase	C00000176 C00000190
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00000176 C00000190
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00000176 C00000190
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00000176 C00000190
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00000176 C00000190
1019	CDK4, CMM3, PSK-J3	cyclin-dependent kinase 4 (EC:2.7.11.22)	C00000176 C00000190
898	CCNE1, CCNE	cyclin E1	C00000176
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00000176

Related Diseases

Diseases related to CTD interactions