PCIDB

KNApSAcK Metabolite C00000206

Metabolite

KNApSAcK Entry

id C00000206
Name Saligel / Salonil / Salicylic acid / 2-Carboxyphenol / o-Hydroxybenzoic acid
CAS RN 69-72-7
Standard InChI InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
Standard InChI (Main Layer) InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)

Cluster

Phytochemical cluster No. 81
KCF-S cluster No. 817

Link

ChEMBL

By standard InChI CHEMBL424
By standard InChI Main Layer CHEMBL424

KEGG

By LinkDB C00805

CTD

By CAS RN D020156

Human Protein / Gene in interaction

124 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL424 CHEMBL1909136 (2)
1 / 0
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr CHEMBL424 CHEMBL823713 (1) CHEMBL953279 (1)
CHEMBL2015664 (1)
0 / 0
Q16637 Survival motor neuron protein Unclassified protein CHEMBL424 CHEMBL1613842 (1)
4 / 2
O94956 Solute carrier organic anion transporter family member 2B1 Unclassified protein CHEMBL424 CHEMBL2075389 (2)
0 / 0
P09917 Arachidonate 5-lipoxygenase Oxidoreductase CHEMBL424 CHEMBL1664429 (1)
0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor CHEMBL424 CHEMBL1909139 (2)
0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase CHEMBL424 CHEMBL1909131 (2)
0 / 3
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) CHEMBL424 CHEMBL1909190 (2)
2 / 2
P08246 Neutrophil elastase S1A CHEMBL424 CHEMBL1909195 (2)
2 / 1
P33765 Adenosine receptor A3 Adenosine receptor CHEMBL424 CHEMBL1909215 (2)
0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 CHEMBL424 CHEMBL1909201 (2)
0 / 0
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor CHEMBL424 CHEMBL1909176 (2)
0 / 0
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase CHEMBL424 CHEMBL992755 (1)
0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase CHEMBL424 CHEMBL992754 (1)
0 / 0
P43166 Carbonic anhydrase 7 Lyase CHEMBL424 CHEMBL992757 (1)
0 / 0
P22894 Neutrophil collagenase M10A CHEMBL424 CHEMBL1664434 (1)
0 / 0
P29466 Caspase-1 C14 CHEMBL424 CHEMBL1909193 (2)
0 / 0
P17252 Protein kinase C alpha type Alpha CHEMBL424 CHEMBL1909198 (2)
0 / 0
P27361 Mitogen-activated protein kinase 3 Erk CHEMBL424 CHEMBL1909199 (2)
0 / 0
P14780 Matrix metalloproteinase-9 M10A CHEMBL424 CHEMBL1664435 (1) CHEMBL1909197 (2)
2 / 2
P00918 Carbonic anhydrase 2 Lyase CHEMBL424 CHEMBL933690 (1) CHEMBL991856 (1)
CHEMBL1002070 (1) CHEMBL1002074 (1)
CHEMBL1909123 (2)
1 / 2
P07550 Beta-2 adrenergic receptor Adrenergic receptor CHEMBL424 CHEMBL1909092 (2)
0 / 1
P21397 Amine oxidase [flavin-containing] A Oxidoreductase CHEMBL424 CHEMBL1909169 (2)
1 / 1
P25021 Histamine H2 receptor Histamine receptor CHEMBL424 CHEMBL1909157 (2)
0 / 0
P35367 Histamine H1 receptor Histamine receptor CHEMBL424 CHEMBL1909156 (2)
0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine CHEMBL424 CHEMBL1909143 (2)
1 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor CHEMBL424 CHEMBL1909174 (2)
0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor CHEMBL424 CHEMBL1909090 (2)
0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor CHEMBL424 CHEMBL1909093 (2)
0 / 0
P02768 Serum albumin Secreted protein CHEMBL424 CHEMBL702885 (1) CHEMBL835062 (1)
CHEMBL1805606 (1) CHEMBL1805607 (1)
CHEMBL1805608 (1) CHEMBL1805609 (1)
0 / 0
P08183 Multidrug resistance protein 1 drug CHEMBL424 CHEMBL2076205 (1)
1 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor CHEMBL424 CHEMBL1909127 (2)
0 / 0
P06241 Tyrosine-protein kinase Fyn Src CHEMBL424 CHEMBL1909204 (2)
0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr CHEMBL424 CHEMBL1909202 (2)
0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL424 CHEMBL1909135 (2)
0 / 1
P08236 Beta-glucuronidase Enzyme CHEMBL424 CHEMBL1071205 (1)
1 / 2
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily CHEMBL424 CHEMBL1909203 (2)
1 / 11
P14416 D(2) dopamine receptor Dopamine receptor CHEMBL424 CHEMBL1909140 (2)
2 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase CHEMBL424 CHEMBL1909130 (2)
0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor CHEMBL424 CHEMBL1909120 (2)
0 / 0
P41145 Kappa-type opioid receptor Opioid receptor CHEMBL424 CHEMBL1909181 (2)
0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor CHEMBL424 CHEMBL1909164 (2)
0 / 0
P29274 Adenosine receptor A2a Adenosine receptor CHEMBL424 CHEMBL1909214 (2)
0 / 0
P23280 Carbonic anhydrase 6 Lyase CHEMBL424 CHEMBL992756 (1) CHEMBL1804479 (1)
0 / 0
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor CHEMBL424 CHEMBL1909175 (2)
0 / 0
P05067 Amyloid beta A4 protein Membrane receptor CHEMBL424 CHEMBL649530 (1)
2 / 2
P50052 Type-2 angiotensin II receptor Angiotensin receptor CHEMBL424 CHEMBL1909096 (2)
1 / 1
O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta Other serine/threonine protein kinase CHEMBL424 CHEMBL1070134 (1)
0 / 0
P17948 Vascular endothelial growth factor receptor 1 Vegfr CHEMBL424 CHEMBL1909118 (2)
0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor CHEMBL424 CHEMBL1909166 (2)
1 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase CHEMBL424 CHEMBL981174 (1)
0 / 0
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL424 CHEMBL1614458 (2)
0 / 0
O43570 Carbonic anhydrase 12 Lyase CHEMBL424 CHEMBL992759 (1)
1 / 2
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 CHEMBL424 CHEMBL1909133 (2)
0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme CHEMBL424 CHEMBL1738606 (1)
0 / 0
O75496 Geminin Unclassified protein CHEMBL424 CHEMBL2114780 (1)
0 / 0
Q8TCC7 Solute carrier family 22 member 8 Antiporter CHEMBL424 CHEMBL2076657 (1) CHEMBL2076228 (1)
CHEMBL2078139 (1)
0 / 0
O60656 UDP-glucuronosyltransferase 1-9 Enzyme CHEMBL424 CHEMBL1743330 (1)
0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase CHEMBL424 CHEMBL1909158 (2)
0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor CHEMBL424 CHEMBL1909088 (2)
0 / 0
P21917 D(4) dopamine receptor Dopamine receptor CHEMBL424 CHEMBL1909142 (2)
0 / 0
P30988 Calcitonin receptor Calcitonin receptor CHEMBL424 CHEMBL1909101 (2)
0 / 0
P35462 D(3) dopamine receptor Dopamine receptor CHEMBL424 CHEMBL1909141 (2)
1 / 0
P41143 Delta-type opioid receptor Opioid receptor CHEMBL424 CHEMBL1909180 (2)
0 / 0
Q92731 Estrogen receptor beta NR3A2 CHEMBL424 CHEMBL1909146 (2)
0 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor CHEMBL424 CHEMBL1909104 (2)
0 / 0
P15121 Aldose reductase Enzyme CHEMBL424 CHEMBL642955 (1) CHEMBL642959 (1)
CHEMBL642961 (1) CHEMBL642962 (1)
0 / 0
P25101 Endothelin-1 receptor Endothelin receptor CHEMBL424 CHEMBL1909144 (2)
0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor CHEMBL424 CHEMBL1909100 (2)
0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor CHEMBL424 CHEMBL1909167 (2)
1 / 0
P00915 Carbonic anhydrase 1 Lyase CHEMBL424 CHEMBL933689 (1) CHEMBL991855 (1)
CHEMBL1002069 (1) CHEMBL1002071 (1)
0 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor CHEMBL424 CHEMBL1909129 (2)
0 / 0
P08311 Cathepsin G S1A CHEMBL424 CHEMBL1909194 (2)
0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor CHEMBL424 CHEMBL1909110 (2)
1 / 0
P03956 Interstitial collagenase M10A CHEMBL424 CHEMBL1664431 (1) CHEMBL1909196 (2)
0 / 1
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor CHEMBL424 CHEMBL1909119 (2)
0 / 0
Q4U2R8 Solute carrier family 22 member 6 Antiporter CHEMBL424 CHEMBL2077503 (1) CHEMBL2077520 (1)
CHEMBL2076041 (1)
0 / 0
P04150 Glucocorticoid receptor NR3C1 CHEMBL424 CHEMBL1909150 (2)
0 / 1
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor CHEMBL424 CHEMBL1909171 (2)
2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor CHEMBL424 CHEMBL1909170 (2)
0 / 0
P21554 Cannabinoid receptor 1 Cannabinoid receptor CHEMBL424 CHEMBL1909122 (2)
0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin CHEMBL424 CHEMBL1909109 (2)
2 / 0
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily CHEMBL424 CHEMBL1909205 (2)
5 / 10
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor CHEMBL424 CHEMBL1909172 (2)
1 / 0
P21452 Substance-K receptor Neurokinin receptor CHEMBL424 CHEMBL1909114 (2)
0 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor CHEMBL424 CHEMBL1909125 (2)
0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor CHEMBL424 CHEMBL1909126 (2)
3 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor CHEMBL424 CHEMBL1909108 (2)
0 / 0
P41597 C-C chemokine receptor type 2 CC chemokine receptor CHEMBL424 CHEMBL1909124 (2)
1 / 0
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL424 CHEMBL1909200 (2)
0 / 0
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme CHEMBL424 CHEMBL1909207 (2)
2 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL424 CHEMBL1909132 (2)
0 / 0
Q16790 Carbonic anhydrase 9 Lyase CHEMBL424 CHEMBL992758 (1)
0 / 1
P08253 72 kDa type IV collagenase M10A CHEMBL424 CHEMBL1664432 (1)
1 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme CHEMBL424 CHEMBL1614038 (2)
2 / 2
P06133 UDP-glucuronosyltransferase 2B4 Enzyme CHEMBL424 CHEMBL1908092 (1)
0 / 0
P36537 UDP-glucuronosyltransferase 2B10 Enzyme CHEMBL424 CHEMBL1908089 (1)
0 / 0
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A CHEMBL424 CHEMBL1909186 (2)
0 / 0
P03372 Estrogen receptor NR3A1 CHEMBL424 CHEMBL1909145 (2)
1 / 1
P08588 Beta-1 adrenergic receptor Adrenergic receptor CHEMBL424 CHEMBL1909091 (2)
1 / 0
P22303 Acetylcholinesterase Hydrolase CHEMBL424 CHEMBL1909212 (2)
1 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor CHEMBL424 CHEMBL1909211 (2)
0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor CHEMBL424 CHEMBL1909105 (2)
0 / 0
P35372 Mu-type opioid receptor Opioid receptor CHEMBL424 CHEMBL1909182 (2)
0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor CHEMBL424 CHEMBL1909173 (2)
0 / 0
P25103 Substance-P receptor Neurokinin receptor CHEMBL424 CHEMBL1909113 (2)
0 / 0
P25105 Platelet-activating factor receptor PAF receptor CHEMBL424 CHEMBL1909187 (2)
0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor CHEMBL424 CHEMBL1909168 (2)
0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL424 CHEMBL1909134 (2)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL424 CHEMBL1909138 (2)
0 / 1
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 CHEMBL424 CHEMBL1909137 (2)
0 / 0
P23975 Sodium-dependent noradrenaline transporter Norepinephrine CHEMBL424 CHEMBL1909094 (2)
1 / 1
P25100 Alpha-1D adrenergic receptor Adrenergic receptor CHEMBL424 CHEMBL1909087 (2)
0 / 0
P30542 Adenosine receptor A1 Adenosine receptor CHEMBL424 CHEMBL1909213 (2)
0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor CHEMBL424 CHEMBL1909089 (2)
0 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 CHEMBL424 CHEMBL1909116 (2)
1 / 1
P07451 Carbonic anhydrase 3 Lyase CHEMBL424 CHEMBL991857 (1)
0 / 0
P06239 Tyrosine-protein kinase Lck Src CHEMBL424 CHEMBL1909206 (2)
0 / 1
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor CHEMBL424 CHEMBL1909128 (2)
0 / 0
P08254 Stromelysin-1 M10A CHEMBL424 CHEMBL813241 (1) CHEMBL1664433 (1)
1 / 0
P22748 Carbonic anhydrase 4 Lyase CHEMBL424 CHEMBL991858 (1)
1 / 1
Q9UHC3 Acid-sensing ion channel 3 Unclassified protein CHEMBL424 CHEMBL1629312 (1)
0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL424 CHEMBL1613914 (1)
0 / 0
Q9NSA0 Solute carrier family 22 member 11 Transporter CHEMBL424 CHEMBL2075518 (1)
0 / 0

CTD interaction (21)

compound gene gene name gene description interaction interaction type form reference
pmid
D020156 1645 AKR1C1
2-ALPHA-HSD
20-ALPHA-HSD
C9
DD1
DD1/DD2
DDH
DDH1
H-37
HAKRC
HBAB
MBAB
aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112) Salicylic Acid results in decreased activity of AKR1C1 protein decreases activity
protein 19010312
D020156 1646 AKR1C2
AKR1C-pseudo
BABP
DD
DD2
DDH2
HAKRD
HBAB
MCDR2
SRXY8
aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357) Salicylic Acid results in decreased activity of AKR1C2 protein decreases activity
protein 19010312
D020156 1646 AKR1C2
AKR1C-pseudo
BABP
DD
DD2
DDH2
HAKRD
HBAB
MCDR2
SRXY8
aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357) Salicylic Acid results in increased expression of AKR1C2 mRNA increases expression
mRNA 20491607
D020156 8644 AKR1C3
DD3
DDX
HA1753
HAKRB
HAKRe
HSD17B5
PGFS
hluPGFS
aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357) Salicylic Acid results in decreased activity of AKR1C3 protein decreases activity
protein 19010312
D020156 3565 IL4
BCGF-1
BCGF1
BSF-1
BSF1
IL-4
interleukin 4 Salicylic Acid results in decreased expression of IL4 mRNA decreases expression
mRNA 11238116
D020156 3565 IL4
BCGF-1
BCGF1
BSF-1
BSF1
IL-4
interleukin 4 Salicylic Acid results in decreased secretion of IL4 protein decreases secretion
protein 11238116
D020156 23764 MAFF
U-MAF
hMafF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F Salicylic Acid results in increased expression of MAFF mRNA increases expression
mRNA 20491607
D020156 4489 MT1A
MT1
MT1S
MTC
metallothionein 1A Salicylic Acid results in increased expression of MT1A mRNA increases expression
mRNA 20491607
D020156 55867 SLC22A11
OAT4
hOAT4
solute carrier family 22 (organic anion/urate transporter), member 11 Salicylic Acid results in decreased activity of SLC22A11 protein decreases activity
protein 12388633
D020156 55867 SLC22A11
OAT4
hOAT4
solute carrier family 22 (organic anion/urate transporter), member 11 SLC22A11 protein results in increased uptake of Salicylic Acid increases uptake
protein 12388633
D020156 9356 SLC22A6
HOAT1
OAT1
PAHT
ROAT1
solute carrier family 22 (organic anion transporter), member 6 Salicylic Acid results in decreased activity of SLC22A6 protein decreases activity
protein 12388633
D020156 9356 SLC22A6
HOAT1
OAT1
PAHT
ROAT1
solute carrier family 22 (organic anion transporter), member 6 SLC22A6 protein results in increased uptake of Salicylic Acid increases uptake
protein 12388633
D020156 10864 SLC22A7
NLT
OAT2
solute carrier family 22 (organic anion transporter), member 7 Salicylic Acid results in decreased activity of SLC22A7 protein decreases activity
protein 12388633
D020156 10864 SLC22A7
NLT
OAT2
solute carrier family 22 (organic anion transporter), member 7 SLC22A7 protein results in increased uptake of Salicylic Acid increases uptake
protein 12388633
D020156 114571 SLC22A9
HOAT4
OAT4
OAT7
UST3H
ust3
solute carrier family 22 (organic anion transporter), member 9 Salicylic Acid results in decreased activity of SLC22A9 protein decreases activity
protein 12388633
D020156 114571 SLC22A9
HOAT4
OAT4
OAT7
UST3H
ust3
solute carrier family 22 (organic anion transporter), member 9 SLC22A9 protein results in increased uptake of Salicylic Acid increases uptake
protein 12388633
D020156 7295 TXN
TRDX
TRX
TRX1
thioredoxin Salicylic Acid results in increased expression of TXN mRNA increases expression
mRNA 20491607
D020156 54575 UGT1A10
UDPGT
UGT-1J
UGT1-10
UGT1.10
UGT1J
UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) UGT1A10 protein results in increased glucuronidation of Salicylic Acid increases glucuronidation
protein 15117964
D020156 54659 UGT1A3
UDPGT
UDPGT_1-3
UGT-1C
UGT1-03
UGT1.3
UGT1C
UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) UGT1A3 protein results in increased glucuronidation of Salicylic Acid increases glucuronidation
protein 15117964
D020156 54577 UGT1A7
UDPGT
UDPGT_1-7
UGT-1G
UGT1-07
UGT1.7
UGT1G
UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) UGT1A7 protein results in increased glucuronidation of Salicylic Acid increases glucuronidation
protein 15117964
D020156 54576 UGT1A8
UDPGT
UDPGT_1-8
UGT-1H
UGT1-08
UGT1.8
UGT1A8S
UGT1H
UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) UGT1A8 protein results in increased glucuronidation of Salicylic Acid increases glucuronidation
protein 15117964

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (50)

OMIM preferred title UniProt
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#103780 Alcohol dependence P08172
P14416
P31645
#104300 Alzheimer disease; ad P05067
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
#300615 Brunner syndrome P21397
#605714 Cerebral amyloid angiopathy, app-related P05067
#614466 Coronary heart disease, susceptibility to, 6; chds6 P08254
#162800 Cyclic neutropenia P08246
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#615363 Estrogen resistance; estrr P03372
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#137800 Glioma susceptibility 1; glm1 P04626
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#143860 Hyperchlorhidrosis, isolated O43570
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#612244 Inflammatory bowel disease 13; ibd13 P08183
#603932 Intervertebral disc disease; idd P14780
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
#608516 Major depressive disorder; mdd P08172
%300852 Mental retardation, x-linked 88; mrx88 P50052
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#253220 Mucopolysaccharidosis, type vii; mps7 P08236
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#126200 Multiple sclerosis, susceptibility to; ms P08575
#159900 Myoclonic dystonia P14416
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#601665 Obesity P32245
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#607276 Resting heart rate, variation in P08588
#600852 Retinitis pigmentosa 17; rp17 P22748
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#190300 Tremor, hereditary essential, 1; etm1 P35462
#610379 West nile virus, susceptibility to P51681
#112100 Yt blood group antigen P22303

KEGG DISEASE (42)

KEGG disease name UniProt
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
P08253 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
Q92731 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00019 Pancreatic cancer P04626 (related)
H00027 Ovarian cancer P04626 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
H00046 Cholangiocarcinoma P04626 (related)
P35354 (related)
H00056 Alzheimer's disease (AD) P05067 (related)
H01185 Cerebral amyloid angiopathy (CAA) P05067 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00079 Asthma P07550 (related)
H00132 Mucopolysaccharidosis type VII (MPS7) P08236 (related)
H00421 Mucopolysaccharidosis (MPS) P08236 (related)
H00100 Neutropenic disorders P08246 (related)
H00025 Penile cancer P08253 (related)
P14780 (related)
P35354 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00548 Brunner syndrome P21397 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
Q16637 (related)

Diseases related to CTD interactions

12 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D001249 D020156 Asthma marker/mechanism
6715990
D003128 D020156 COMA marker/mechanism
6484774
D004342 D020156 Drug Hypersensitivity marker/mechanism
6715990
D034381 D020156 Hearing Loss therapeutic
10418821
D006685 D020156 Hoarseness marker/mechanism
6715990
D007819 D020156 Laryngeal Edema marker/mechanism
6715990
D009668 D020156 Nose Diseases marker/mechanism
6715990
D049188 D020156 Prenatal Injuries marker/mechanism
4502305
D012640 D020156 Seizures marker/mechanism
6484774
D014012 D020156 Tinnitus marker/mechanism
18632935
D014581 D020156 Urticaria marker/mechanism
6715990
D014860 D020156 Warts therapeutic
12852385