Rhaponticum carthamoides

• Index
• Plant Species
• Metabolite list (97)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Rhaponticum carthamoides
Genus	Rhaponticum
Family	Asteraceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Rhaponticum carthamoides
Linked NCBI taxonomy ID	362630
Linked level	species

Family

Family in NCBI taxonomy	Asteraceae
ID	4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (97)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00002378	Cyanin / Cyanidin 3,5-diglucoside					No. 1	No. 15
C00005529	Isorhamnetin 5-glucoside					No. 2	No. 15
C00005382	Quercimeritrin / Quercetin 7-glucoside / Quercetin 7-O-beta-D-glucoside	CHEMBL248726	C089996			No. 2	No. 15
C00005379	Quercetin 5-glucoside / Quercetin 5-O-beta-D-glucopyranoside	CHEMBL1255591				No. 2	No. 15
C00005374	Quercetin	CHEMBL82242 CHEMBL479232 CHEMBL1437696	C012526	14 / 2 / 2	2 / 1	No. 2	No. 15
C00002374	Chrysanthemin / Cyanidin 3-O-glucoside	CHEMBL257839 CHEMBL1197952	C114438	1 / 0 / 1		No. 2	No. 15
C00005307	6-Hydroxykaempferol 7-glucoside	CHEMBL462992				No. 2	No. 15
C00004680	Patuletin / 6-Methoxyquercetin / 3,5,7,3',4'-Pentahydroxy-6-methoxyflavone / 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-6-methoxy-4H-1-benzopyran-4-one	CHEMBL465155	C079162			No. 3	No. 15
C00004639	Quercetin 3,3'-dimethyl ether / 5,7,4'-Trihydroxy-3,3'-dimethoxyflavone / 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-methoxy-4H-1-benzopyran-4-one	CHEMBL511363	C060385			No. 3	No. 15
C00004635	Isorhamnetin / 3'-O-Methylquercetin / 3,4',5,7-Tetrahydroxy-3'-methoxyflavone / 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one	CHEMBL379064	C047368	12 / 10 / 13	10 / 0	No. 3	No. 15
C00004593	6-Methoxykaempferol / 3,5,7,4'-Tetrahydroxy-6-methoxyflavone / 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one	CHEMBL462898				No. 3	No. 15
C00004677	Quercetagetin	CHEMBL413552	C079163	3 / 0 / 1	1 / 1	No. 3	No. 15
C00000968	Hesperetin	CHEMBL88169 CHEMBL399121 CHEMBL1589200	C013015	42 / 50 / 65	18 / 3	No. 25	No. 14
C00000960	Eriodictyol	CHEMBL8996 CHEMBL307893 CHEMBL1975989	C007619	32 / 29 / 55	5 / 0	No. 25	No. 14
C00048470	Leuzeasterone / (+)-Leuzeasterone					No. 58	No. 11
C00048265	20-Hydroxyecdysone 2-acetate					No. 58	No. 11
C00048522	Rapisterone B					No. 58	No. 11
C00048521	Rapisterone					No. 58	No. 11
C00048346	Carthamoleusterone / (+)-Carthamoleusterone					No. 58	No. 11
C00048347	Carthamosterone					No. 58	No. 11
C00048256	1beta-Hydroxymakisterone C / (+)-1beta-Hydroxymakisterone C					No. 58	No. 11
C00048475	Makisterone C	CHEMBL2087159		1 / 1 / 0		No. 58	No. 11
C00048253	15-Hydroxyponasterone A / (+)-15-Hydroxyponasterone A					No. 58	No. 11
C00048348	Carthamosterone A					No. 58	No. 11
C00048266	22-Deoxy-28-hydroxymakisterone C / (+)-22-Deoxy-28-hydroxymakisterone C					No. 58	No. 11
C00048241	(24Z)-29-Hydroxy-24(28)-dehydromakisterone C / (+)-(24Z)-29-Hydroxy-24(28)-dehydromakisterone C					No. 58	No. 11
C00003643	Ajugasterone C	CHEMBL477336		1 / 1 / 0		No. 58	No. 11
C00003655	Inokosterone	CHEMBL564971 CHEMBL1967672	C100084			No. 58	No. 11
C00003666	Polypodine B	CHEMBL522181 CHEMBL502028 CHEMBL1567145		1 / 1 / 0		No. 58	No. 11
C00048318	Amarasterone A					No. 58	No. 11
C00041169	Taxisterone	CHEMBL2087145		1 / 1 / 0		No. 58	No. 11
C00048267	22-Oxo-20-hydroxyecdysone					No. 58	No. 11
C00048314	alpha-Ecdysone	CHEMBL549300 CHEMBL1456897	D004440	4 / 4 / 7		No. 58	No. 11
C00048269	24(28)-Dehydroamarasterone B					No. 58	No. 11
C00048270	24(28)-Dehydromakisterone A					No. 58	No. 11
C00048271	24-epi-Makisterone A	CHEMBL255034		1 / 0 / 1		No. 58	No. 11
C00048272	26-Hydroxymakisterone C / (+)-26-Hydroxymakisterone C					No. 58	No. 11
C00048273	2-Deoxyecdysterone	CHEMBL2087143		1 / 1 / 0		No. 58	No. 11
C00048286	3-epi-20-Hydroxyecdysone	CHEMBL224128 CHEMBL490151 CHEMBL477132 CHEMBL1707235 CHEMBL2087148 CHEMBL2087156 CHEMBL2087157 CHEMBL2354392		6 / 2 / 1		No. 58	No. 11
C00048523	Rapisterone D	CHEMBL522181 CHEMBL502028 CHEMBL1567145		1 / 1 / 0		No. 58	No. 11
C00048292	5alpha-20-Hydroxyecdysone / (+)-5alpha-20-Hydroxyecdysone	CHEMBL224128 CHEMBL490151 CHEMBL477132 CHEMBL1707235 CHEMBL2087148 CHEMBL2087156 CHEMBL2087157 CHEMBL2354392		6 / 2 / 1		No. 58	No. 11
C00048469	Lesterone	CHEMBL2087140		1 / 1 / 0		No. 58	No. 11
C00048439	Isovitexirone					No. 58	No. 11
C00039714	Makisterone A	CHEMBL255034		1 / 0 / 1		No. 58	No. 11
C00033543	20-Hydroxyecdysone	CHEMBL224128 CHEMBL490151 CHEMBL477132 CHEMBL1707235 CHEMBL2087148 CHEMBL2087156 CHEMBL2087157 CHEMBL2354392		6 / 2 / 1		No. 58	No. 11
C00048431	Integristerone B					No. 58	No. 11
C00048349	Carthamosterone B					No. 58	No. 11
C00048429	Integristerone A	CHEMBL2087144		1 / 1 / 0		No. 58	No. 11
C00041214	Turkesterone	CHEMBL2087140	C017787	1 / 1 / 0		No. 58	No. 11
C00003817	Apigenin / 5,7,4'-Trihydroxyflavone	CHEMBL28	D047310	164 / 119 / 105	68 / 8	No. 71	No. 15
C00004565	Kaempferol / Nimbecetin / Rhamnolutein / Pelargidenolon / 5,7,4'-Trihydroxyflavonol / 3,5,7,4'-Tetrahydroxyflavone / 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one	CHEMBL150	C006552	76 / 69 / 87	86 / 8	No. 71	No. 15
C00000674	Luteolin	CHEMBL151	D047311	99 / 91 / 95	76 / 6	No. 71	No. 15
C00048297	7-epi-alpha-Selinene					No. 151	No. 38
C00003186	beta-Selinene		C087920			No. 151	No. 38
C00029671	alpha-Muurolene					No. 283	No. 39
C00030807	Neochlorogenic acid / 5-Caffeoylquinic acid / 5-O-Caffeoylquinic acid	CHEMBL284616 CHEMBL230481 CHEMBL249450 CHEMBL1332980 CHEMBL1394423 CHEMBL1419611 CHEMBL1473644 CHEMBL1552319		30 / 19 / 22		No. 314	No. 6
C00002724	Heriguard / Chlorogenic acid / 3-O-Caffeoylquinic acid	CHEMBL284616 CHEMBL230481 CHEMBL249450 CHEMBL1332980 CHEMBL1394423 CHEMBL1419611 CHEMBL1473644 CHEMBL1552319	D002726	30 / 19 / 22	37 / 9	No. 314	No. 6
C00003118	Copaene / alpha-Copaene / (-)-alpha-Copaene					No. 333	No. 38
C00000816	beta-Pinene	CHEMBL501351	C010789			No. 476	No. 35
C00000805	alpha-Pinene	CHEMBL442565	C005451	3 / 3 / 2	0 / 1	No. 476	No. 35
C00021310	gamma-Himachalene					No. 478	No. 38
C00003110	Caryophyllene / (E)-Caryophyllene / beta-Caryophyllene / (-)-(E)-Caryophyllene / (E)-beta-Caryophyllene	CHEMBL445740 CHEMBL448700		2 / 3 / 7		No. 478	No. 38
C00021227	alpha-Gurjunene					No. 595	No. 38
C00021230	Aromadendrene / (+)-Aromadendrene / (+)-Aromadendr-7(15)-ene	CHEMBL509805 CHEMBL596664				No. 640
C00002647	Gallic acid	CHEMBL288114	D005707	42 / 53 / 68	52 / 16	No. 817	No. 81
C00048480	m-Hydroxybenzoic acid	CHEMBL65369	C032948	9 / 2 / 4		No. 817	No. 81
C00000206	Saligel / Salonil / Salicylic acid / 2-Carboxyphenol / o-Hydroxybenzoic acid	CHEMBL424	D020156	124 / 50 / 42	15 / 12	No. 817	No. 81
C00002668	Protocatechuic acid / 3,4-Dihydroxybenzoic acid	CHEMBL37537	C009091	33 / 19 / 19	2 / 0	No. 817	No. 81
C00002648	Gentisic acid / 2,5-Dihydroxybenzoic acid	CHEMBL1461	C010925	15 / 6 / 8	2 / 1	No. 817	No. 81
C00000856	4-Hydroxybenzoic acid / p-Hydroxybenzoic acid	CHEMBL441343	C038193	21 / 7 / 16	2 / 1	No. 817	No. 81
C00000823	Limonene	CHEMBL15799 CHEMBL449062	C008281	7 / 21 / 48	6 / 6	No. 848	No. 35
C00002729	o-Coumaric acid	CHEMBL52564	C085894	17 / 6 / 17		No. 904	No. 6
C00000615	Caffeic acid	CHEMBL145 CHEMBL1320034		68 / 64 / 63		No. 904	No. 6
C00000152	p-Coumaric acid	CHEMBL66879 CHEMBL2336752	C032171	23 / 13 / 18	6 / 1	No. 904	No. 6
C00021877	Rotundene					No. 926
C00048262	1-p-Menthene					No. 1052	No. 35
C00002674	Syringic acid / 4-Hydroxy-3,5-dimethoxybenzoic acid	CHEMBL1414	C001945	12 / 3 / 5		No. 1073
C00002682	Vanillic acid / 3-Methoxy-4-hydroxybenzoic acid	CHEMBL120568	D014641	5 / 3 / 3	5 / 0	No. 1073
C00048514	Polypodine B 20,22-acetonide	CHEMBL2087542		1 / 1 / 0		No. 1315
C00048428	Inokosterone 20,22-acetonide					No. 1315
C00048264	20-Hydroxyecdysone 2,3-monoacetonide / (+)-20-Hydroxyecdysone 2,3-monoacetonide					No. 1315
C00048430	Integristerone A 20,22-acetonide	CHEMBL2087537		1 / 1 / 0		No. 1315
C00002743	Ferulic acid / 3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid	CHEMBL32749	C004999	110 / 52 / 40	16 / 6	No. 1366	No. 6
C00002776	Sinapic acid	CHEMBL109341	C073734	5 / 5 / 5	0 / 5	No. 1366	No. 6
C00007453	Cyclohexane / beta-Elemene	CHEMBL448502 CHEMBL479707				No. 1400
C00021283	Cyperene					No. 1454
C00003181	beta-Santalene					No. 1957	No. 38
C00000207	Benzoic acid	CHEMBL541	D019817	97 / 39 / 33	24 / 1	No. 2192
C00048532	Selina-3,7-diene					No. 2307
C00048377	Dihydrorubrosterone					No. 2794	No. 55
C00048528	Rubrosterone	CHEMBL2087163	C000552	1 / 1 / 0		No. 2794	No. 55
C00021859	Cyclosativene / (+)-Cyclosativene					No. 2870
C00012011	delta-Elemene					No. 4001
C00048252	14-epi-Ponasterone A 22-glucoside / (+)-14-epi-Ponasterone A 22-glucoside					No. 4197
C00048320	Aplotaxene					No. 4317
C00030933	p-Cymen-8-ol					No. 8611
C00048376	Dehydro isolongifolene					No. 8647

Human Protein / Gene in interactions

346 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P08183	Multidrug resistance protein 1	drug	C00000206 C00000674 C00003643 C00003666 C00003817 C00004565 C00033543 C00041169 C00041214 C00048273 C00048286 C00048292 C00048314 C00048429 C00048430 C00048469 C00048475 C00048514 C00048523 C00048528	1 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000152 C00000206 C00000207 C00000615 C00000674 C00000823 C00002647 C00002724 C00002743 C00002776 C00003817 C00004565 C00030807	0 / 3
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000206 C00000207 C00000615 C00000674 C00000960 C00000968 C00002724 C00002743 C00003817 C00004565 C00030807 C00039714 C00048271	0 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000206 C00000207 C00000615 C00000674 C00000960 C00000968 C00002724 C00002743 C00003817 C00004565 C00004635 C00030807	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00000152 C00000206 C00000207 C00000615 C00000856 C00002647 C00002648 C00002668 C00002674 C00002729 C00002743 C00048480	1 / 2
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00000206 C00000615 C00000674 C00000960 C00002647 C00002668 C00002724 C00002743 C00003817 C00004565 C00005374 C00030807	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00000674 C00000960 C00000968 C00002648 C00002668 C00002682 C00003817 C00004565 C00005374 C00033543 C00048286 C00048292	0 / 0
O75496	Geminin	Unclassified protein	C00000206 C00000674 C00000960 C00000968 C00002668 C00002724 C00002743 C00003817 C00030807 C00033543 C00048286 C00048292	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00000206 C00000615 C00000674 C00000960 C00000968 C00002647 C00002724 C00003817 C00004565 C00005374 C00030807	0 / 0
P03372	Estrogen receptor	NR3A1	C00000152 C00000206 C00000207 C00000615 C00000674 C00002647 C00002668 C00002682 C00002743 C00003817 C00004565	1 / 1
O43570	Carbonic anhydrase 12	Lyase	C00000152 C00000206 C00000615 C00000856 C00002647 C00002648 C00002668 C00002674 C00002729 C00002743 C00048480	1 / 2
P15121	Aldose reductase	Enzyme	C00000152 C00000206 C00000615 C00002647 C00002668 C00002674 C00002682 C00002724 C00004565 C00005374 C00030807	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00000152 C00000206 C00000615 C00000856 C00002647 C00002648 C00002668 C00002674 C00002729 C00002743 C00048480	0 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00000152 C00000206 C00000615 C00000856 C00002647 C00002648 C00002668 C00002674 C00002729 C00002743 C00048480	0 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000206 C00000207 C00000615 C00000674 C00000968 C00002724 C00002743 C00003817 C00004565 C00030807	1 / 0
P43166	Carbonic anhydrase 7	Lyase	C00000152 C00000206 C00000615 C00000856 C00002647 C00002648 C00002668 C00002674 C00002729 C00002743	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00000615 C00000674 C00000960 C00002647 C00002668 C00002724 C00002776 C00003817 C00005374 C00030807	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000206 C00000207 C00000615 C00000674 C00000968 C00002724 C00002743 C00003817 C00004565 C00030807	0 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000206 C00000207 C00000615 C00000674 C00000968 C00002724 C00002743 C00003817 C00004565 C00030807	1 / 1
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00000615 C00000674 C00000960 C00002647 C00002724 C00003817 C00004565 C00004635 C00005374 C00030807	0 / 0
Q9ULX7	Carbonic anhydrase 14	Lyase	C00000152 C00000206 C00000615 C00000856 C00002647 C00002648 C00002668 C00002674 C00002729 C00002743	0 / 0
P23280	Carbonic anhydrase 6	Lyase	C00000152 C00000206 C00000615 C00000856 C00002647 C00002668 C00002674 C00002729 C00002743 C00048480	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00000206 C00000207 C00000615 C00000805 C00000960 C00000968 C00002647 C00002743 C00003817	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00000615 C00000674 C00000960 C00000968 C00002647 C00002724 C00003817 C00004565 C00030807	3 / 3
P04150	Glucocorticoid receptor	NR3C1	C00000206 C00000207 C00000674 C00002647 C00002724 C00002743 C00003817 C00004565 C00030807	0 / 1
P22748	Carbonic anhydrase 4	Lyase	C00000152 C00000206 C00000615 C00000856 C00002647 C00002668 C00002674 C00002729 C00002743	1 / 1
Q13093	Platelet-activating factor acetylhydrolase	Enzyme	C00000152 C00000615 C00002647 C00002668 C00002724 C00002743 C00002776 C00030807	3 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00000615 C00000674 C00000960 C00000968 C00002647 C00002668 C00003817 C00004565	4 / 3
P22303	Acetylcholinesterase	Hydrolase	C00000206 C00000207 C00000674 C00000960 C00000968 C00002743 C00003817 C00004565	1 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00000615 C00000674 C00002729 C00002743 C00003817 C00004565 C00004635 C00005374	1 / 1
P16473	Thyrotropin receptor	Glycohormone receptor	C00000207 C00000615 C00000674 C00000805 C00000968 C00002724 C00003817 C00030807	3 / 2
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00000152 C00000206 C00000207 C00000615 C00000856 C00002743 C00003817 C00004565	1 / 8
P07451	Carbonic anhydrase 3	Lyase	C00000152 C00000206 C00000615 C00000856 C00002647 C00002674 C00002729 C00002743	0 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000206 C00000207 C00000615 C00000674 C00002743 C00002776 C00003817 C00004565	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00000206 C00000615 C00000674 C00000960 C00000968 C00002647 C00003817 C00004565	2 / 2
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00000152 C00000206 C00000615 C00000856 C00002647 C00002674 C00002729 C00002743	0 / 0
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00000152 C00000206 C00000615 C00000856 C00002647 C00002674 C00002729 C00002743	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000615 C00000674 C00003110 C00003817 C00004565 C00004635 C00048314	1 / 2
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00000206 C00000207 C00000615 C00002724 C00002743 C00004565 C00030807	2 / 2
O75164	Lysine-specific demethylase 4A	Enzyme	C00000615 C00000674 C00000960 C00002724 C00004565 C00005374 C00030807	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00000674 C00000823 C00002647 C00002724 C00003817 C00004565 C00030807	0 / 0
P06239	Tyrosine-protein kinase Lck	Src	C00000206 C00000207 C00000674 C00002724 C00002743 C00003817 C00030807	0 / 1
Q9UBT6	DNA polymerase kappa	Enzyme	C00000615 C00000674 C00000960 C00002647 C00003817 C00004635 C00005374	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00000615 C00000674 C00002647 C00002724 C00003817 C00004565 C00030807	1 / 1
P04637	Cellular tumor antigen p53	Transcription Factor	C00000674 C00000823 C00000960 C00000968 C00002647 C00003817 C00004565	7 / 37
P14780	Matrix metalloproteinase-9	M10A	C00000206 C00000207 C00000615 C00000674 C00002648 C00002668 C00002743	2 / 2
O00255	Menin	Unclassified protein	C00000615 C00000674 C00003110 C00003817 C00004565 C00004635 C00048314	2 / 5
P03956	Interstitial collagenase	M10A	C00000206 C00000207 C00000615 C00000674 C00002648 C00002668 C00002743	0 / 1
P39748	Flap endonuclease 1	Enzyme	C00000674 C00000960 C00003817 C00004565 C00004635 C00005374	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00000674 C00000968 C00003817 C00033543 C00048286 C00048292	0 / 0
Q16678	Cytochrome P450 1B1	Cytochrome P450 1B1	C00000674 C00000960 C00000968 C00003817 C00004565 C00004635	4 / 4
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00000206 C00000615 C00002648 C00002668 C00004565 C00004635	0 / 0
P04798	Cytochrome P450 1A1	Cytochrome P450 1A1	C00000674 C00000960 C00000968 C00003817 C00004565 C00004635	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00000615 C00000674 C00000823 C00002647 C00003817 C00004565	11 / 10
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00000615 C00000674 C00000968 C00003817 C00004565	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000206 C00000207 C00000968 C00002743 C00003817	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00000206 C00000207 C00000968 C00002743 C00003817	0 / 0
Q8TDS4	Hydroxycarboxylic acid receptor 2	Hydroxycarboxylic acid receptor	C00000152 C00000615 C00002729 C00002743 C00048480	0 / 0
P08253	72 kDa type IV collagenase	M10A	C00000206 C00000615 C00000674 C00002648 C00002668	1 / 3
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00000206 C00000207 C00000856 C00002724 C00030807	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000615 C00000674 C00002647 C00002724 C00030807	0 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00000206 C00000207 C00000968 C00002743 C00003817	0 / 0
P04745	Alpha-amylase 1	Enzyme	C00000674 C00000968 C00004565 C00004635 C00004677	0 / 0
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00000206 C00000207 C00000674 C00002743 C00003817	1 / 1
Q9Y253	DNA polymerase eta	Enzyme	C00000674 C00000960 C00003817 C00004565 C00005374	1 / 1
Q16637	Survival motor neuron protein	Unclassified protein	C00000206 C00000674 C00000968 C00002647 C00003817	4 / 1
P14679	Tyrosinase	Oxidoreductase	C00000152 C00000615 C00000674 C00002743 C00004565	4 / 2
P10145	Interleukin-8	Secreted protein	C00002647 C00002724 C00003817 C00030807	0 / 0
O60218	Aldo-keto reductase family 1 member B10	Enzyme	C00000152 C00000615 C00002724 C00030807	0 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00000206 C00000207 C00002743 C00003817	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00000206 C00000207 C00002743 C00003817	0 / 1
Q16539	Mitogen-activated protein kinase 14	p38	C00000206 C00000207 C00002743 C00003817	0 / 0
P06746	DNA polymerase beta	Enzyme	C00000615 C00000674 C00000960 C00002668	0 / 0
P11309	Serine/threonine-protein kinase pim-1	Pim	C00000674 C00003817 C00004565 C00004677	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00000674 C00000968 C00003817 C00004565	1 / 1
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00000615 C00000674 C00000960 C00002668	1 / 1
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00000674 C00000968 C00003817 C00004565	2 / 0
P17252	Protein kinase C alpha type	Alpha	C00000206 C00000207 C00002743 C00003817	0 / 0
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00000207 C00000856 C00002724 C00030807	0 / 0
P36888	Receptor-type tyrosine-protein kinase FLT3	Pdgfr	C00000674 C00000960 C00003817 C00004565	1 / 1
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00000206 C00000615 C00002648 C00048480	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00000206 C00000207 C00002743 C00003817	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00000823 C00000968 C00003817 C00004565	0 / 0
P08254	Stromelysin-1	M10A	C00000206 C00000674 C00002648 C00002668	1 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00000615 C00000674 C00000823 C00003817	3 / 1
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00000674 C00000960 C00003817 C00004565	0 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00000206 C00000207 C00002743	0 / 0
Q00535	Cyclin-dependent kinase 5	Cdk5	C00000674 C00003817 C00004565	0 / 0
Q15078	Cyclin-dependent kinase 5 activator 1	REG serine/threonine protein kinase family	C00000674 C00003817 C00004565	0 / 0
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00000968 C00003817 C00004565	0 / 0
Q9NPH5	NADPH oxidase 4	Enzyme	C00000674 C00003817 C00004565	0 / 0
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00000206 C00000207 C00002743	0 / 0
P14635	G2/mitotic-specific cyclin-B1	Other cytosolic protein	C00000674 C00003817 C00004565	0 / 0
P37059	Estradiol 17-beta-dehydrogenase 2	Enzyme	C00000968 C00003817 C00004565	0 / 0
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00000823 C00003817 C00004565	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00002647 C00002743 C00003817	5 / 1
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00000615 C00002729 C00003817	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00000206 C00000207 C00002743	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00000206 C00000207 C00002743	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00000206 C00000207 C00002743	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00000206 C00000207 C00002743	0 / 0
O95067	G2/mitotic-specific cyclin-B2	Other cytosolic protein	C00000674 C00003817 C00004565	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00000206 C00000207 C00002743	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00000674 C00003817 C00004565	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00000206 C00000207 C00002743	0 / 0
P14416	D(2) dopamine receptor	Dopamine receptor	C00000206 C00000207 C00002743	2 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00000206 C00000207 C00002743	1 / 1
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00000206 C00000207 C00002743	0 / 0
P28907	ADP-ribosyl cyclase 1	Enzyme	C00000674 C00002374 C00004677	0 / 1
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00000206 C00000207 C00002743	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00000206 C00000207 C00002743	0 / 0
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00000206 C00000207 C00002743	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00000206 C00000207 C00002743	0 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00000206 C00000207 C00002743	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00000206 C00000207 C00002743	0 / 0
Q9Y3R4	Sialidase-2	Enzyme	C00000674 C00003817 C00004565	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00000206 C00000207 C00002743	1 / 1
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00000206 C00000207 C00002743	1 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00000674 C00000960 C00004565	0 / 0
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00000206 C00000207 C00002743	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00000206 C00000207 C00002743	1 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00000674 C00000968 C00003817	0 / 0
P06493	Cyclin-dependent kinase 1	Cdc2	C00000674 C00003817 C00004565	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00000206 C00000207 C00002743	0 / 0
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00000206 C00000207 C00002743	0 / 1
P27361	Mitogen-activated protein kinase 3	Erk	C00000206 C00000207 C00002743	0 / 0
Q9UQ49	Sialidase-3	Enzyme	C00000207 C00000856 C00048480	0 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00000206 C00000207 C00002743	0 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00000206 C00000207 C00002743	0 / 0
P25021	Histamine H2 receptor	Histamine receptor	C00000206 C00000207 C00002743	0 / 0
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00000805 C00003817 C00004565	0 / 0
P29466	Caspase-1	C14	C00000206 C00000207 C00002743	0 / 0
Q01196	Runt-related transcription factor 1	Unclassified protein	C00000674 C00002668 C00003817	1 / 4
P22894	Neutrophil collagenase	M10A	C00000206 C00002648 C00002668	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00000206 C00000207 C00002743	0 / 0
P10275	Androgen receptor	NR3C4	C00000674 C00003817 C00004565	3 / 4
O00167	Eyes absent homolog 2	Enzyme	C00033543 C00048286 C00048292	0 / 0
Q8WWL7	G2/mitotic-specific cyclin-B3	Other cytosolic protein	C00000674 C00003817 C00004565	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00000206 C00000207 C00002743	1 / 0
P49840	Glycogen synthase kinase-3 alpha	Gsk	C00000674 C00003817 C00004565	0 / 0
P04062	Glucosylceramidase	Enzyme	C00000674 C00003817 C00004565	6 / 4
P38398	Breast cancer type 1 susceptibility protein	Enzyme	C00000674 C00000968 C00003817	4 / 2
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00000206 C00000207 C00002743	0 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00000206 C00000207 C00002743	1 / 1
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00000206 C00000207 C00002743	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00000206 C00000207 C00002743	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00000206 C00000207 C00002743	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00000206 C00000207 C00002743	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00000206 C00000207 C00002743	1 / 0
Q00534	Cyclin-dependent kinase 6	CMGC serine/threonine protein kinase family	C00000674 C00003817 C00004565	1 / 0
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00000206 C00000207 C00002743	0 / 0
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00000206 C00000207 C00002743	0 / 0
P14061	Estradiol 17-beta-dehydrogenase 1	Enzyme	C00000968 C00003817 C00004565	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00000206 C00000207 C00002743	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00000206 C00000207 C00002743	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00000206 C00000207 C00002743	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00000206 C00000207 C00002743	1 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00000206 C00000207 C00002743	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00000674 C00003817 C00004565	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00000206 C00000207 C00002743	0 / 0
P08311	Cathepsin G	S1A	C00000206 C00000207 C00002743	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00000206 C00000207 C00002743	1 / 0
P08246	Neutrophil elastase	S1A	C00000206 C00000207 C00002743	2 / 1
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00000206 C00000207 C00002743	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00000206 C00000207 C00002743	3 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00000206 C00000207 C00002743	1 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00000206 C00000207 C00002743	0 / 0
P06276	Cholinesterase	Hydrolase	C00000674 C00003817 C00004565	0 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00000206 C00000207 C00002743	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00000674 C00002668 C00003817	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00000206 C00000207 C00002743	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00000206 C00000207 C00002743	0 / 0
P14618	Pyruvate kinase PKM	Enzyme	C00000960 C00000968 C00003817	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00000206 C00000207 C00002743	0 / 0
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00000206 C00000207 C00002743	1 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00000206 C00000207 C00002743	5 / 9
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00000968 C00003817 C00004565	5 / 3
P83916	Chromobox protein homolog 1	Unclassified protein	C00000968 C00002648 C00048314	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00000674 C00000960 C00003817	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00000674 C00003817 C00004565	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00000206 C00000207 C00002743	0 / 0
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00000206 C00000207 C00002743	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00000206 C00000207 C00002743	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00000206 C00000207 C00002743	2 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00000206 C00000207 C00002743	2 / 1
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00033543 C00048286 C00048292	1 / 1
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00000856 C00003817	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00000674 C00000960	2 / 1
P33527	Multidrug resistance-associated protein 1	drugs	C00003817 C00004565	0 / 0
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00002668 C00005374	0 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00002743 C00003817	3 / 0
P17516	Aldo-keto reductase family 1 member C4	Enzyme	C00000152 C00000615	1 / 0
Q12791	Calcium-activated potassium channel subunit alpha-1	KCNM, KCa1.x	C00003817 C00004565	1 / 1
P12931	Proto-oncogene tyrosine-protein kinase Src	Src	C00002724 C00030807	0 / 0
P09874	Poly [ADP-ribose] polymerase 1	Enzyme	C00000674 C00003817	0 / 0
P40763	Signal transducer and activator of transcription 3	Transcription Factor	C00002724 C00030807	1 / 2
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00000615 C00000674	0 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00000206 C00000207	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00000615 C00000674	1 / 1
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00000856 C00003817	0 / 0
P27338	Amine oxidase [flavin-containing] B	Oxidoreductase	C00000674 C00003817	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00000968 C00003817	1 / 0
P42224	Signal transducer and activator of transcription 1-alpha/beta	Unclassified protein	C00002724 C00030807	3 / 3
Q96RI1	Bile acid receptor	NR1H4	C00003817 C00004565	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00000674 C00000960	0 / 0
Q12794	Hyaluronidase-1	Enzyme	C00000615 C00002743	1 / 2
P35869	Aryl hydrocarbon receptor	Transcription Factor	C00003817 C00004565	0 / 0
Q04760	Lactoylglutathione lyase	Enzyme	C00000674 C00004565	0 / 0
O95271	Tankyrase-1	Enzyme	C00000674 C00003817	0 / 0
P02768	Serum albumin	Secreted protein	C00000206 C00002668	0 / 0
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00002743 C00003817	0 / 0
P24941	Cyclin-dependent kinase 2	Cdc2	C00000674 C00003817	0 / 0
P52895	Aldo-keto reductase family 1 member C2	Enzyme	C00000152 C00000615	1 / 0
Q15046	Lysine--tRNA ligase	Enzyme	C00000674 C00003817	2 / 1
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00000674 C00003817	2 / 0
Q9GZT9	Egl nine homolog 1	Enzyme	C00000615 C00002668	1 / 1
P16109	P-selectin	Adhesion	C00002647 C00002668	1 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00000206 C00002647	0 / 0
P14151	L-selectin	Adhesion	C00002647 C00002668	0 / 0
P51692	Signal transducer and activator of transcription 5B	Unclassified protein	C00002724 C00030807	1 / 1
Q04828	Aldo-keto reductase family 1 member C1	Enzyme	C00000152 C00000615	0 / 0
P51580	Thiopurine S-methyltransferase	Enzyme	C00000856 C00002682	1 / 1
O15118	Niemann-Pick C1 protein	Unclassified protein	C00000968 C00003817	1 / 1
Q01453	Peripheral myelin protein 22	Unclassified protein	C00000615 C00003817	5 / 2
P42330	Aldo-keto reductase family 1 member C3	Enzyme	C00000152 C00000615	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00002647 C00003817	2 / 3
P16581	E-selectin	Adhesion	C00002647 C00002668	0 / 0
Q9H2K2	Tankyrase-2	Enzyme	C00000674 C00003817	0 / 0
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00003817	2 / 2
P06133	UDP-glucuronosyltransferase 2B4	Enzyme	C00000206	0 / 0
P36537	UDP-glucuronosyltransferase 2B10	Enzyme	C00000206	0 / 0
O14763	Tumor necrosis factor receptor superfamily member 10B	Unclassified protein	C00000674	1 / 0
P68871	Hemoglobin subunit beta	Secreted protein	C00003817	4 / 4
P02647	Apolipoprotein A-I	Unclassified protein	C00000968	3 / 2
O14920	Inhibitor of nuclear factor kappa-B kinase subunit beta	Other serine/threonine protein kinase	C00000206	0 / 0
P12821	Angiotensin-converting enzyme	M2	C00002647	4 / 2
P05067	Amyloid beta A4 protein	Membrane receptor	C00000206	2 / 2
O75582	Ribosomal protein S6 kinase alpha-5	CAMK serine/threonine protein kinase MSKB subfamily	C00003817	0 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00002776	2 / 2
P11387	DNA topoisomerase 1	Isomerase	C00000674	0 / 0
Q9GZU7	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1	Enzyme	C00004565	0 / 0
Q9HAW7	UDP-glucuronosyltransferase 1-7	Enzyme	C00000856	0 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00000674	1 / 0
Q9HC97	G-protein coupled receptor 35	Kynurenic acid receptor	C00000674	0 / 0
Q8IW41	MAP kinase-activated protein kinase 5	CAMK serine/threonine protein kinase MAPKAPK	C00003817	0 / 0
O75116	Rho-associated protein kinase 2	Rock	C00003817	0 / 0
P51570	Galactokinase	Enzyme	C00000674	1 / 1
P07948	Tyrosine-protein kinase Lyn	Src	C00003817	0 / 0
Q02880	DNA topoisomerase 2-beta	Isomerase	C00003817	0 / 0
P54132	Bloom syndrome protein	Enzyme	C00000674	1 / 2
P31749	RAC-alpha serine/threonine-protein kinase	Akt	C00003817	4 / 1
P09769	Tyrosine-protein kinase Fgr	Src	C00003817	0 / 0
O00141	Serine/threonine-protein kinase Sgk1	AGC serine/threonine protein kinase SGK subfamily	C00003817	0 / 0
Q92887	Canalicular multispecific organic anion transporter 1	Unclassified protein	C00003817	1 / 1
P42858	Huntingtin	Unclassified protein	C00002682	1 / 1
P04792	Heat shock protein beta-1	Unclassified protein	C00004635	2 / 1
Q9Y4K4	Mitogen-activated protein kinase kinase kinase kinase 5	STE serine/threonine protein kinase KHS subfamily	C00003817	0 / 0
P14920	D-amino-acid oxidase	Enzyme	C00000207	0 / 0
P07237	Protein disulfide-isomerase	Enzyme	C00005374	0 / 0
P98170	E3 ubiquitin-protein ligase XIAP	Other cytosolic protein	C00004565	1 / 1
P24385	G1/S-specific cyclin-D1	Other cytosolic protein	C00002729	1 / 8
P51151	Ras-related protein Rab-9A	Unclassified protein	C00000968	0 / 0
Q6W5P4	Neuropeptide S receptor	Neuropeptide receptor	C00003817	1 / 0
Q8TCC7	Solute carrier family 22 member 8	Antiporter	C00000206	0 / 0
P11802	Cyclin-dependent kinase 4	CMGC serine/threonine protein kinase family	C00002729	1 / 3
P08236	Beta-glucuronidase	Enzyme	C00000206	1 / 2
P23443	Ribosomal protein S6 kinase beta-1	p70	C00003817	0 / 0
P56817	Beta-secretase 1	A1A	C00003817	0 / 0
Q99549	M-phase phosphoprotein 8	Unclassified protein	C00003817	0 / 0
P49327	Fatty acid synthase	Transferase	C00000674	0 / 0
P78536	Disintegrin and metalloproteinase domain-containing protein 17	M12B	C00002647	1 / 0
P51452	Dual specificity protein phosphatase 3	Ser_Thr_Tyr	C00000615	0 / 0
P10696	Alkaline phosphatase, placental-like	Enzyme	C00000960	0 / 1
P34969	5-hydroxytryptamine receptor 7	Serotonin receptor	C00002743	0 / 0
P68400	Casein kinase II subunit alpha	Ck2	C00003817	0 / 0
P51649	Succinate-semialdehyde dehydrogenase, mitochondrial	Oxidoreductase	C00000856	1 / 1
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00003817	0 / 0
Q9BXC0	Hydroxycarboxylic acid receptor 1	Hydroxycarboxylic acid receptor	C00048480	0 / 0
Q99489	D-aspartate oxidase	Enzyme	C00000207	0 / 0
Q13315	Serine-protein kinase ATM	Atypical serine/threonine protein kinase PIKK subfamily	C00000968	1 / 4
P07711	Cathepsin L1	C1A	C00002668	0 / 0
P54646	5'-AMP-activated protein kinase catalytic subunit alpha-2	Ampk	C00003817	0 / 0
P35236	Tyrosine-protein phosphatase non-receptor type 7	Tyr	C00000615	0 / 0
O14757	Serine/threonine-protein kinase Chk1	Chk1	C00003817	0 / 0
P43405	Tyrosine-protein kinase SYK	Syk	C00003817	0 / 0
Q8N1Q1	Carbonic anhydrase 13	Lyase	C00002729	0 / 0
P48147	Prolyl endopeptidase	S9A	C00004565	0 / 0
Q13627	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	CMGC dual-specificity kinase DYRK1	C00003817	1 / 0
P39900	Macrophage metalloelastase	M10A	C00000674	0 / 0
P53778	Mitogen-activated protein kinase 12	p38	C00003817	0 / 0
P08581	Hepatocyte growth factor receptor	TK tyrosine-protein kinase MET subfamily	C00002647	2 / 3
P37173	TGF-beta receptor type-2	TKL dual-specificity kinase STKR type 2 subfamily	C00000968	4 / 3
P04406	Glyceraldehyde-3-phosphate dehydrogenase	Enzyme	C00002647	0 / 0
Q9UHC3	Acid-sensing ion channel 3	Unclassified protein	C00000206	0 / 0
P24298	Alanine aminotransferase 1	Enzyme	C00000615	0 / 0
Q06124	Tyrosine-protein phosphatase non-receptor type 11	Tyr	C00000615	4 / 2
Q13133	Oxysterols receptor LXR-alpha	NR1H3	C00000968	0 / 0
P40225	Thrombopoietin	Unclassified protein	C00003817	1 / 1
P41240	Tyrosine-protein kinase CSK	Csk	C00003817	0 / 0
P18054	Arachidonate 12-lipoxygenase, 12S-type	Enzyme	C00000674	2 / 0
O15530	3-phosphoinositide-dependent protein kinase 1	Pdk1	C00003817	0 / 0
Q15759	Mitogen-activated protein kinase 11	p38	C00003817	0 / 0
P49137	MAP kinase-activated protein kinase 2	CAMK serine/threonine protein kinase MAPKAPK	C00003817	0 / 0
P45452	Collagenase 3	M10A	C00000674	1 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00003817	2 / 0
Q15418	Ribosomal protein S6 kinase alpha-1	Rskb	C00003817	0 / 0
O15264	Mitogen-activated protein kinase 13	p38	C00003817	0 / 0
Q9UN88	Gamma-aminobutyric acid receptor subunit theta	GABA-A theta	C00003817	0 / 0
P28472	Gamma-aminobutyric acid receptor subunit beta-3	GABA-A beta	C00003817	1 / 0
P14867	Gamma-aminobutyric acid receptor subunit alpha-1	GABA-A alpha	C00003817	1 / 1
P48169	Gamma-aminobutyric acid receptor subunit alpha-4	GABA-A alpha	C00003817	0 / 0
O14764	Gamma-aminobutyric acid receptor subunit delta	GABA-A delta	C00003817	1 / 1
P31644	Gamma-aminobutyric acid receptor subunit alpha-5	GABA-A alpha	C00003817	0 / 0
Q99928	Gamma-aminobutyric acid receptor subunit gamma-3	GABA-A gamma	C00003817	0 / 0
P78334	Gamma-aminobutyric acid receptor subunit epsilon	GABA-A epsilon	C00003817	0 / 0
Q8N1C3	Gamma-aminobutyric acid receptor subunit gamma-1	GABA-A gamma	C00003817	0 / 0
P34903	Gamma-aminobutyric acid receptor subunit alpha-3	GABA-A alpha	C00003817	0 / 0
O00591	Gamma-aminobutyric acid receptor subunit pi	GABA-A pi	C00003817	0 / 0
P47870	Gamma-aminobutyric acid receptor subunit beta-2	GABA-A beta	C00003817	0 / 0
P18507	Gamma-aminobutyric acid receptor subunit gamma-2	GABA-A gamma	C00003817	4 / 2
P18505	Gamma-aminobutyric acid receptor subunit beta-1	GABA-A beta	C00003817	0 / 0
Q16445	Gamma-aminobutyric acid receptor subunit alpha-6	GABA-A alpha	C00003817	0 / 0
P47869	Gamma-aminobutyric acid receptor subunit alpha-2	GABA-A alpha	C00003817	1 / 0
P45983	Mitogen-activated protein kinase 8	Jnk	C00003817	0 / 0
P53779	Mitogen-activated protein kinase 10	Jnk	C00003817	0 / 1
P45984	Mitogen-activated protein kinase 9	Jnk	C00003817	0 / 0
Q9NSA0	Solute carrier family 22 member 11	Transporter	C00000206	0 / 0
P27487	Dipeptidyl peptidase 4	S9B	C00004565	0 / 1
Q9GZT4	Serine racemase	Enzyme	C00000207	0 / 0
Q9P1W9	Serine/threonine-protein kinase pim-2	Pim	C00005374	0 / 0
P05186	Alkaline phosphatase, tissue-nonspecific isozyme	Enzyme	C00000960	3 / 1
P22694	cAMP-dependent protein kinase catalytic subunit beta	Pka	C00003817	0 / 0
P17612	cAMP-dependent protein kinase catalytic subunit alpha	Pka	C00003817	0 / 0
P22612	cAMP-dependent protein kinase catalytic subunit gamma	Pka	C00003817	0 / 0
P07900	Heat shock protein HSP 90-alpha	Other cytosolic protein	C00000615	0 / 0
P08238	Heat shock protein HSP 90-beta	Other cytosolic protein	C00000615	0 / 0
P80404	4-aminobutyrate aminotransferase, mitochondrial	Transferase	C00000856	1 / 1
Q9HCP0	Casein kinase I isoform gamma-1	Ck1	C00003817	0 / 0
P48730	Casein kinase I isoform delta	Ck1	C00003817	1 / 0
P49674	Casein kinase I isoform epsilon	Ck1	C00003817	0 / 0
P78368	Casein kinase I isoform gamma-2	Ck1	C00003817	0 / 0
P48729	Casein kinase I isoform alpha	Ck1	C00003817	0 / 0
Q02750	Dual specificity mitogen-activated protein kinase kinase 1	Ste7	C00003817	1 / 1
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00004565	0 / 0
Q4U2R8	Solute carrier family 22 member 6	Antiporter	C00000206	0 / 0
P09923	Intestinal-type alkaline phosphatase	Enzyme	C00000960	0 / 0

236 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000152 C00000674 C00000823 C00000968 C00002743 C00003817 C00004565 C00004635 C00005374
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000674 C00000823 C00000968 C00002647 C00003817 C00004565
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00000674 C00000968 C00002647 C00002743 C00003817 C00004565
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00000674 C00000960 C00000968 C00003817 C00004565 C00004635
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00000206 C00002682 C00002724 C00002743 C00003817 C00004565
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00000206 C00002682 C00002724 C00002743 C00003817 C00004565
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00000206 C00000674 C00002682 C00002724 C00002743 C00004565
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00000206 C00002682 C00002724 C00002743 C00003817 C00004565
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00000152 C00000674 C00002647 C00002743 C00004565
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00000152 C00000856 C00002647 C00002648 C00003817
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000823 C00000968 C00002647 C00003817 C00004565
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00000674 C00003817 C00004565 C00004635 C00005374
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00000152 C00000207 C00002682 C00002724 C00004635
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00000674 C00002647 C00002743 C00003817 C00004565
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00000674 C00002647 C00002743 C00003817 C00004565
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00000674 C00000968 C00003817 C00004565 C00004635
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000674 C00000968 C00002647 C00003817 C00004565
3565	IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4	interleukin 4	C00000206 C00000674 C00003817 C00004565
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00000152 C00002743 C00003817 C00004565
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00000674 C00002647 C00003817 C00004565
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00000674 C00002647 C00003817 C00004565
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00000674 C00003817 C00004565 C00004635
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00000674 C00003817 C00004565 C00004635
581	BAX, BCL2L4	BCL2-associated X protein	C00000674 C00000968 C00002647 C00004565
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00000968 C00002647 C00003817 C00004565
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00000674 C00003817 C00004565
8000	PSCA, PRO232	prostate stem cell antigen	C00000674 C00003817 C00004565
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00000207 C00000823 C00000960
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00000674 C00003817 C00004565
8839	WISP2, CCN5, CT58, CTGF-L	WNT1 inducible signaling pathway protein 2	C00000674 C00003817 C00004565
891	CCNB1, CCNB	cyclin B1	C00000674 C00003817 C00004565
983	CDK1, CDC2, CDC28A, P34CDC2	cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)	C00000674 C00003817 C00004565
1031	CDKN2C, INK4C, p18, p18-INK4C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	C00000674 C00003817 C00004565
5241	PGR, NR3C3, PR	progesterone receptor	C00002724 C00003817 C00004565
847	CAT	catalase (EC:1.11.1.6)	C00000674 C00000968 C00003817
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00000674 C00000968 C00002647
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00000674 C00003817 C00004565
7402	UTRN, DMDL, DRP, DRP1	utrophin	C00000968 C00003817 C00004565
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00002647 C00004565 C00004635
7299	TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3	tyrosinase (EC:1.14.18.1)	C00000152 C00002724 C00002743
7295	TXN, TRDX, TRX, TRX1	thioredoxin	C00000206 C00000207 C00002724
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00000674 C00003817 C00004565
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00000674 C00002647 C00003817
9540	TP53I3, PIG3	tumor protein p53 inducible protein 3	C00000674 C00003817 C00004565
8626	TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L	tumor protein p63	C00000674 C00003817 C00004565
2203	FBP1, FBP	fructose-1,6-bisphosphatase 1 (EC:3.1.3.11)	C00000674 C00003817 C00004565
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00000674 C00003817 C00004565
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00000674 C00002647 C00003817
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00000207 C00003817 C00004565
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00000674 C00002647 C00003817
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00000674 C00003817 C00004565
7161	TP73, P73	tumor protein p73	C00000674 C00003817 C00004565
4793	NFKBIB, IKBB, TRIP9	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	C00000674 C00002647 C00003817
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00000674 C00002647 C00003817
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00000674 C00003817 C00004565
1588	CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM	cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000968 C00003817
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00000674 C00004565
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00000960 C00004565
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00000674 C00002647
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00002647 C00004565
2938	GSTA1, GST2, GSTA1-1, GTH1	glutathione S-transferase alpha 1 (EC:2.5.1.18)	C00000207 C00004565
4616	GADD45B, GADD45BETA, MYD118	growth arrest and DNA-damage-inducible, beta	C00000674 C00004565
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00003817 C00004565
1950	EGF, HOMG4, URG	epidermal growth factor	C00000674 C00002724
4502	MT2A, MT2	metallothionein 2A	C00000207 C00004565
331	XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3	X-linked inhibitor of apoptosis	C00000674 C00002647
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00000674 C00002647
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00000960 C00004565
1437	CSF2, GMCSF	colony stimulating factor 2 (granulocyte-macrophage)	C00000674 C00004565
1645	AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB	aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112)	C00000206 C00000207
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00000674 C00000968
1147	CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16	conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10)	C00002647 C00004565
1080	CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49)	C00003817 C00004565
8644	AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS	aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357)	C00000206 C00000207
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00000674 C00004565
2539	G6PD, G6PD1	glucose-6-phosphate dehydrogenase (EC:1.1.1.49)	C00000207 C00002648
2810	SFN, YWHAS	stratifin	C00000674 C00004565
29110	TBK1, NAK, T2K	TANK-binding kinase 1 (EC:2.7.11.1)	C00000674 C00000960
4489	MT1A, MT1, MT1S, MTC	metallothionein 1A	C00000206 C00000207
472	ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1	ataxia telangiectasia mutated (EC:2.7.11.1)	C00002647 C00004565
7031	TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2	trefoil factor 1	C00004565 C00004635
405	ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2	aryl hydrocarbon receptor nuclear translocator	C00003817 C00004565
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00000674 C00003817
958	CD40, Bp50, CDW40, TNFRSF5, p50	CD40 molecule, TNF receptor superfamily member 5	C00000674 C00003817
4312	MMP1, CLG, CLGN	matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7)	C00000674 C00003817
6401	SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2	selectin E	C00000674 C00003817
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00000674 C00003817
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00003817 C00004565
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00000968 C00002743
1589	CYP21A2, CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B	cytochrome P450, family 21, subfamily A, polypeptide 2 (EC:1.14.99.10)	C00003817
7039	TGFA, TFGA	transforming growth factor, alpha	C00004565
7019	TFAM, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3	transcription factor A, mitochondrial	C00004565
6773	STAT2, ISGF-3, P113, STAT113	signal transducer and activator of transcription 2, 113kDa	C00004565
6513	SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED	solute carrier family 2 (facilitated glucose transporter), member 1	C00004565
3265	HRAS, C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1	Harvey rat sarcoma viral oncogene homolog	C00000823
4852	NPY, PYY4	neuropeptide Y	C00000823
1312	COMT	catechol-O-methyltransferase (EC:2.1.1.6)	C00002668
2023	ENO1, ENO1L1, MPB1, NNE, PPH	enolase 1, (alpha) (EC:4.2.1.11)	C00002668
6119	RPA3, REPA3	replication protein A3, 14kDa	C00004565
10891	PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	C00004565
10257	ABCC4, EST170205, MOAT-B, MOATB, MRP4	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	C00000968
10057	ABCC5, ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	C00000968
9970	NR1I3, CAR, CAR1, MB67	nuclear receptor subfamily 1, group I, member 3	C00004565
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00004565
1019	CDK4, CMM3, PSK-J3	cyclin-dependent kinase 4 (EC:2.7.11.22)	C00000968
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00004565
8202	NCOA3, ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP	nuclear receptor coactivator 3 (EC:2.3.1.48)	C00004565
4586	MUC5AC, MUC5, TBM, leB	mucin 5AC, oligomeric mucus/gel-forming	C00004565
3952	LEP, LEPD, OB, OBS	leptin	C00000856
4973	OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1	oxidized low density lipoprotein (lectin-like) receptor 1	C00004635
5320	PLA2G2A, MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2	phospholipase A2, group IIA (platelets, synovial fluid) (EC:3.1.1.4)	C00004677
47	ACLY, ACL, ATPCL, CLATP	ATP citrate lyase (EC:2.3.3.8)	C00002724
358	AQP1, AQP-CHIP, CHIP28, CO	aquaporin 1	C00002724
360	AQP3, AQP-3, GIL	aquaporin 3 (Gill blood group)	C00002724
367	AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM	androgen receptor	C00002724
960	CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1	CD44 molecule (Indian blood group)	C00002724
999	CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO	cadherin 1, type 1, E-cadherin (epithelial)	C00002724
1277	COL1A1, OI4	collagen, type I, alpha 1	C00002724
4512	COX1, COI, MTCO1, MT-CO1	cytochrome c oxidase subunit I	C00002724
114757	CYGB, HGB, STAP	cytoglobin	C00002724
1830	DSG3, CDHF6, PVA	desmoglein 3	C00002724
110357			C00004565
2200	FBN1, ACMICD, ECTOL1, FBN, GPHYSD2, MASS, MFS1, OCTD, SGS, SSKS, WMS, WMS2	fibrillin 1	C00002724
2201	FBN2, CCA, DA9	fibrillin 2	C00002724
2246	FGF1, AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-1, FGF-alpha, FGFA, GLIO703, HBGF-1, HBGF1	fibroblast growth factor 1 (acidic)	C00002724
2896	GRN, CLN11, GEP, GP88, PCDGF, PEPI, PGRN	granulin	C00002724
3036	HAS1, HAS	hyaluronan synthase 1 (EC:2.4.1.212)	C00002724
3315	HSPB1, CMT2F, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27	heat shock 27kDa protein 1	C00002724
3552	IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1	interleukin 1, alpha	C00002724
3852	KRT5, CK5, DDD, DDD1, EBS2, K5, KRT5A	keratin 5	C00002724
4157	MC1R, CMM5, MSH-R, SHEP2	melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)	C00002724
8985	PLOD3, LH3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (EC:1.14.11.4)	C00002724
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00002724
5886	RAD23A, HHR23A, HR23A	RAD23 homolog A (S. cerevisiae)	C00002724
5914	RARA, NR1B1, RAR	retinoic acid receptor, alpha	C00002724
6256	RXRA, NR2B1	retinoid X receptor, alpha	C00002724
6649	SOD3, EC-SOD	superoxide dismutase 3, extracellular (EC:1.15.1.1)	C00002724
6716	SRD5A2	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (EC:1.3.1.22)	C00002724
7178	TPT1, HRF, TCTP, p02, p23	tumor protein, translationally-controlled 1	C00002724
4233	MET, AUTS9, HGFR, RCCP2, c-Met	met proto-oncogene (EC:2.7.10.1)	C00004565
7306	TYRP1, CAS2, CATB, GP75, OCA3, TRP, TRP1, TYRP, b-PROTEIN	tyrosinase-related protein 1 (EC:1.14.18.-)	C00002724
25	ABL1, ABL, JTK7, bcr/abl, c-ABL, p150, v-abl	c-abl oncogene 1, non-receptor tyrosine kinase (EC:2.7.10.2)	C00002647
338	APOB, FLDB, LDLCQ4	apolipoprotein B	C00002647
545	ATR, FCTCS, FRP1, MEC1, SCKL, SCKL1	ataxia telangiectasia and Rad3 related (EC:2.7.11.1)	C00002647
613	BCR, ALL, BCR1, CML, D22S11, D22S662, PHL	breakpoint cluster region (EC:2.7.11.1)	C00002647
4297	KMT2A, ALL-1, CXXC7, HRX, HTRX1, MLL, MLL/GAS7, MLL1A, TET1-MLL, TRX1, WDSTS	lysine (K)-specific methyltransferase 2A (EC:2.1.1.43)	C00004565
898	CCNE1, CCNE	cyclin E1	C00002647
998	CDC42, CDC42Hs, G25K	cell division cycle 42	C00002647
7852	CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM	chemokine (C-X-C motif) receptor 4	C00002647
356	FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6	Fas ligand (TNF superfamily, member 6)	C00002647
2551	GABPA, E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A, RCH04A07	GA binding protein transcription factor, alpha subunit 60kDa	C00002647
2885	GRB2, ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2	growth factor receptor-bound protein 2	C00002647
3551	IKBKB, IKK-beta, IKK2, IKKB, NFKBIKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10)	C00002647
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00002647
3949	LDLR, FH, FHC, LDLCQ2	low density lipoprotein receptor	C00002647
5604	MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1	mitogen-activated protein kinase kinase 1 (EC:2.7.12.2)	C00002647
3567	IL5, EDF, IL-5, TRF	interleukin 5 (colony-stimulating factor, eosinophil)	C00004565
3082	HGF, DFNB39, F-TCF, HGFB, HPTA, SF	hepatocyte growth factor (hepapoietin A; scatter factor)	C00004565
4255	MGMT	O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63)	C00002647
4313	MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24)	C00002647
4316	MMP7, MMP-7, MPSL1, PUMP-1	matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23)	C00002647
3043	HBB, CD113t-C, beta-globin	hemoglobin, beta	C00004565
3014	H2AFX, H2A.X, H2A/X, H2AX	H2A histone family, member X	C00004565
5578	PRKCA, AAG6, PKC-alpha, PKCA, PRKACA	protein kinase C, alpha (EC:2.7.11.13)	C00002647
5591	PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350	protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1)	C00002647
5879	RAC1, Rac-1, TC-25, p21-Rac1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	C00002647
19412			C00002647
9687	GREB1	growth regulation by estrogen in breast cancer 1	C00004565
387	RHOA, ARH12, ARHA, RHO12, RHOH12	ras homolog family member A	C00002647
388	RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6	ras homolog family member B	C00002647
6195	RPS6KA1, HU-1, MAPKAPK1A, RSK, RSK1	ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1)	C00002647
9252	RPS6KA5, MSK1, MSPK1, RLPK	ribosomal protein S6 kinase, 90kDa, polypeptide 5 (EC:2.7.11.1)	C00002647
6622	SNCA, NACP, PARK1, PARK4, PD1	synuclein, alpha (non A4 component of amyloid precursor)	C00002647
7224	TRPC5, TRP5	transient receptor potential cation channel, subfamily C, member 5	C00002647
1734	DIO2, 5DII, D2, DIOII, SelY, TXDI2	deiodinase, iodothyronine, type II (EC:1.97.1.10)	C00004565
37618			C00004565
231	AKR1B1, ADR, ALDR1, ALR2, AR	aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21)	C00000207
57016	AKR1B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI	aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2)	C00000207
1401	CRP, PTX1	C-reactive protein, pentraxin-related	C00004565
6352	CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP	chemokine (C-C motif) ligand 5	C00004565
2235	FECH, EPP, FCE	ferrochelatase (EC:4.99.1.1)	C00000207
2512	FTL, NBIA3	ferritin, light polypeptide	C00000207
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00000207
2936	GSR	glutathione reductase (EC:1.8.1.7)	C00000207
4097	MAFG, hMAF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G	C00000207
4199	ME1, HUMNDME, MES	malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40)	C00000207
27113	BBC3, JFY-1, JFY1, PUMA	BCL2 binding component 3	C00004565
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00000207
5226	PGD, 6PGD	phosphogluconate dehydrogenase (EC:1.1.1.44)	C00000207
22949	PTGR1, LTB4DH, PGR1, ZADH3	prostaglandin reductase 1 (EC:1.3.1.48 1.3.1.74)	C00000207
6566	SLC16A1, HHF7, MCT, MCT1	solute carrier family 16 (monocarboxylate transporter), member 1	C00000207
140809	SRXN1, C20orf139, Npn3, SRX, SRX1	sulfiredoxin 1 (EC:1.8.98.2)	C00000207
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00000207
1646	AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8	aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357)	C00000206
23764	MAFF, U-MAF, hMafF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F	C00000206
55867	SLC22A11, OAT4, hOAT4	solute carrier family 22 (organic anion/urate transporter), member 11	C00000206
9356	SLC22A6, HOAT1, OAT1, PAHT, ROAT1	solute carrier family 22 (organic anion transporter), member 6	C00000206
10864	SLC22A7, NLT, OAT2	solute carrier family 22 (organic anion transporter), member 7	C00000206
114571	SLC22A9, HOAT4, OAT4, OAT7, UST3H, ust3	solute carrier family 22 (organic anion transporter), member 9	C00000206
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00003817
239	ALOX12, 12-LOX, 12S-LOX, LOG12	arachidonate 12-lipoxygenase (EC:1.13.11.31)	C00004565
6319	SCD, FADS5, MSTP008, SCD1, SCDOS	stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1)	C00002743
6387	CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B	chemokine (C-X-C motif) ligand 12	C00003817
1584	CYP11B1, CPN1, CYP11B, FHI, P450C11	cytochrome P450, family 11, subfamily B, polypeptide 1 (EC:1.14.15.4)	C00003817
1586	CYP17A1, CPT7, CYP17, P450C17, S17AH	cytochrome P450, family 17, subfamily A, polypeptide 1 (EC:1.14.99.9 4.1.2.30)	C00003817
7352	UCP3, SLC25A9	uncoupling protein 3 (mitochondrial, proton carrier)	C00004565
2064	ERBB2, CD340, HER-2, HER-2/neu, HER2, MLN_19, NEU, NGL, TKR1	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1)	C00003817
3091	HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	C00003817
3284	HSD3B2, HSD3B, HSDB, SDR11E2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (EC:1.1.1.145 5.3.3.1)	C00003817
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00002743
5562	PRKAA1, AMPK, AMPKa1	protein kinase, AMP-activated, alpha 1 catalytic subunit (EC:2.7.11.1 2.7.11.26 2.7.11.27 2.7.11.31)	C00003817
6198	RPS6KB1, PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70_S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha	ribosomal protein S6 kinase, 70kDa, polypeptide 1 (EC:2.7.11.1)	C00003817
5742	PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00002743
6783	SULT1E1, EST, EST-1, ST1E1, STE	sulfotransferase family 1E, estrogen-preferring, member 1 (EC:2.8.2.4)	C00003817
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00003817
23621	BACE1, ASP2, BACE, HSPC104	beta-site APP-cleaving enzyme 1 (EC:3.4.23.46)	C00002743
9429	ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1	ATP-binding cassette, sub-family G (WHITE), member 2	C00000674
177	AGER, RAGE	advanced glycosylation end product-specific receptor	C00000674
329	BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1	baculoviral IAP repeat containing 2	C00000674
890	CCNA2, CCN1, CCNA	cyclin A2	C00000674
972	CD74, DHLAG, HLADG, II, Ia-GAMMA	CD74 molecule, major histocompatibility complex, class II invariant chain	C00000674
1577	CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3	cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1)	C00000674
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00000674
1958	EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225	early growth response 1	C00000674
2354	FOSB, AP-1, G0S3, GOS3, GOSB	FBJ murine osteosarcoma viral oncogene homolog B	C00000674
3726	JUNB, AP-1	jun B proto-oncogene	C00000674
3727	JUND, AP-1	jun D proto-oncogene	C00000674
5602	MAPK10, JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK	mitogen-activated protein kinase 10 (EC:2.7.11.24)	C00000674
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00000674
9572	NR1D1, EAR1, THRA1, THRAL, ear-1, hRev	nuclear receptor subfamily 1, group D, member 1	C00000674
5347	PLK1, PLK, STPK13	polo-like kinase 1 (EC:2.7.11.21)	C00000674
5747	PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK	protein tyrosine kinase 2 (EC:2.7.10.2)	C00000674
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00000674
7128	TNFAIP3, A20, OTUD7C, TNFA1P2	tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12)	C00000674
8743	TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL	tumor necrosis factor (ligand) superfamily, member 10	C00000674
10451	VAV3	vav 3 guanine nucleotide exchange factor	C00000674

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