PCIDB

KNApSAcK Metabolite C00002729

Metabolite

KNApSAcK Entry

id C00002729
Name o-Coumaric acid
CAS RN 583-17-5
Standard InChI InChI=1S/C9H8O3/c10-8-4-2-1-3-7(8)5-6-9(11)12/h1-6,10H,(H,11,12)/b6-5+
Standard InChI (Main Layer) InChI=1S/C9H8O3/c10-8-4-2-1-3-7(8)5-6-9(11)12/h1-6,10H,(H,11,12)

Cluster

Phytochemical cluster No. 6
KCF-S cluster No. 904

Link

ChEMBL

By standard InChI CHEMBL52564
By standard InChI Main Layer CHEMBL52564

KEGG

By LinkDB C01772

CTD

By CAS RN C085894

Human Protein / Gene in interaction

17 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase CHEMBL52564 CHEMBL1227478 (1)
0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase CHEMBL52564 CHEMBL1227477 (1)
0 / 0
P43166 Carbonic anhydrase 7 Lyase CHEMBL52564 CHEMBL1227480 (1)
0 / 0
Q8N1Q1 Carbonic anhydrase 13 Lyase CHEMBL52564 CHEMBL1227626 (1)
0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase CHEMBL52564 CHEMBL2051343 (1) CHEMBL2051344 (1)
1 / 1
P00918 Carbonic anhydrase 2 Lyase CHEMBL52564 CHEMBL1227474 (1) CHEMBL1670882 (1)
CHEMBL1938063 (1)
1 / 2
P11802 Cyclin-dependent kinase 4 CMGC serine/threonine protein kinase family CHEMBL52564 CHEMBL665280 (1)
1 / 3
P24385 G1/S-specific cyclin-D1 Other cytosolic protein CHEMBL52564 CHEMBL665280 (1)
1 / 10
P23280 Carbonic anhydrase 6 Lyase CHEMBL52564 CHEMBL1227479 (1)
0 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase CHEMBL52564 CHEMBL1227627 (1)
0 / 0
O43570 Carbonic anhydrase 12 Lyase CHEMBL52564 CHEMBL1227625 (1) CHEMBL1670884 (1)
1 / 2
Q8TDS4 Hydroxycarboxylic acid receptor 2 Hydroxycarboxylic acid receptor CHEMBL52564 CHEMBL1772554 (1)
0 / 0
P00915 Carbonic anhydrase 1 Lyase CHEMBL52564 CHEMBL1227473 (1) CHEMBL1670881 (1)
CHEMBL1938062 (1)
0 / 0
Q16790 Carbonic anhydrase 9 Lyase CHEMBL52564 CHEMBL1228226 (1) CHEMBL1670883 (1)
CHEMBL1938064 (1)
0 / 1
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor CHEMBL52564 CHEMBL1291967 (1)
0 / 0
P07451 Carbonic anhydrase 3 Lyase CHEMBL52564 CHEMBL1227475 (1)
0 / 0
P22748 Carbonic anhydrase 4 Lyase CHEMBL52564 CHEMBL1227476 (1)
1 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#143860 Hyperchlorhidrosis, isolated O43570
#609048 Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 P11802
#254500 Myeloma, multiple P24385
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#600852 Retinitis pigmentosa 17; rp17 P22748
#278300 Xanthinuria, type i P47989

KEGG DISEASE (17)

KEGG disease name UniProt
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00030 Cervical cancer P11802 (related)
H00038 Malignant melanoma P11802 (related)
H00042 Glioma P11802 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H00006 Hairy-cell leukemia P24385 (related)
H00010 Multiple myeloma P24385 (related)
H00016 Oral cancer P24385 (related)
P24385 (marker)
H00017 Esophageal cancer P24385 (related)
H00031 Breast cancer P24385 (related)
H00055 Laryngeal cancer P24385 (related)
P24385 (marker)
H00559 von Hippel-Lindau syndrome P24385 (related)
H00047 Gallbladder cancer P24385 (marker)
H00192 Xanthinuria P47989 (related)