Species

KNApSAcK Entry

Organism name Citrus spp.
Genus Citrus
Family Rutaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Citrus
Linked NCBI taxonomy ID 2706
Linked level genus

Family

Family in NCBI taxonomy Rutaceae
ID 23513

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (49)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00006376 External link 512 Vitexin 2''-O-xyloside
No. 1 No. 15
C00004732 External link 512 Gossypetin 8,4'-dimethyl ether
No. 3 No. 15
C00008386 External link 512 Narirutin 4'-glucoside
No. 5 No. 15
C00008387 External link 512 Naringin 4'-glucoside
No. 5 No. 15
C00008296 External link 512 Hesperetin 5-O-glucoside
CHEMBL463462
C069231
No. 12 No. 14
C00000954 External link 512 Senegalensein
/ Lonchocarpol A
/ 6,8-Diprenylnaringenin
CHEMBL477969
CHEMBL1545584
C068505
16 / 26 / 18 No. 19 No. 14
C00006121 External link 512 8-C-beta-D-Glucopyranosyldiosmetin
/ 8-beta-D-Glucopyranosyl-5,7,3'-trihydroxy-4'-methoxyflavone
/ 8-beta-D-Glucopyranosyl-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
No. 22 No. 15
C00000968 External link 512 Hesperetin
CHEMBL88169
CHEMBL399121
CHEMBL1589200
C013015
42 / 50 / 65 18 / 3 No. 25 No. 14
C00000992 External link 512 Pinocembrin
CHEMBL70518
CHEMBL399910
CHEMBL399249
C016063
18 / 23 / 23 5 / 0 No. 25 No. 14
C00000982 External link 512 Naringenin
/ (-)-Naringenin
CHEMBL9352
CHEMBL32571
C005273
57 / 46 / 40 35 / 10 No. 25 No. 14
C00003776 External link 512 Lutein
/ (all-E)-Lutein
/ all-trans-(+)-Xanthophyll
/ (3R,3'R,6'R)-beta,epsilon-Carotene-3,3'-diol
CHEMBL173929
CHEMBL172477
CHEMBL1559643
CHEMBL1979448
D014975
4 / 2 / 3 7 / 2 No. 26 No. 59
C00000920 External link 512 beta-Cryptoxanthin
C010564
No. 26 No. 59
C00000987 External link 512 Neohesperidin
CHEMBL506398
CHEMBL1885559
1 / 0 / 0 No. 48 No. 14
C00000986 External link 512 Neoeriocitrin
No. 48 No. 14
C00000984 External link 512 Narirutin
CHEMBL446246
CHEMBL507672
CHEMBL1441712
No. 48 No. 14
C00000995 External link 512 Poncirin
/ Isosakuranetin-7-O-beta-D-neohesperidoside
CHEMBL451050
No. 48 No. 14
C00000983 External link 512 Naringin
CHEMBL451532
CHEMBL451512
CHEMBL1742953
CHEMBL1970019
C005274
18 / 12 / 6 12 / 4 No. 48 No. 14
C00000970 External link 512 Hesperidin
CHEMBL265606
CHEMBL449317
CHEMBL1314714
CHEMBL1328143
CHEMBL1535112
CHEMBL1574000
CHEMBL2140112
D006569
24 / 9 / 14 10 / 5 No. 48 No. 14
C00008295 External link 512 Eriocitrin
CHEMBL2165586
No. 48 No. 14
C00008223 External link 512 Didymin
No. 48 No. 14
C00000911 External link 512 Lycopene
/ all-trans-Lycopene
CHEMBL501174
CHEMBL1984187
C015329
6 / 13 / 13 84 / 13 No. 97 No. 59
C00003787 External link 512 Violaxanthin
C005613
No. 114 No. 59
C00008450 External link 512 Citflavanone
No. 127 No. 14
C00003722 External link 512 Nomilin
CHEMBL500167
C059405
0 / 1 No. 204 No. 51
C00003719 External link 512 Limonin
CHEMBL1523286
CHEMBL1886762
CHEMBL1897224
CHEMBL2004366
C001546
2 / 0 / 1 1 / 1 No. 204 No. 51
C00003723 External link 512 Obacunone
CHEMBL404140
C067207
1 / 0 / 0 8 / 0 No. 204 No. 51
C00012816 External link 512 (+)-Intermedeol
/ 5beta,10alpha-Eudesm-11-en-4-ol
CHEMBL481844
CHEMBL505457
No. 398 No. 38
C00002488 External link 512 Osthol
/ Osthole
CHEMBL52229
C046627
12 / 6 / 5 7 / 4 No. 466 No. 25
C00000805 External link 512 alpha-Pinene
CHEMBL442565
C005451
3 / 3 / 2 0 / 1 No. 476 No. 35
C00003110 External link 512 Caryophyllene
/ (E)-Caryophyllene
/ beta-Caryophyllene
/ (-)-(E)-Caryophyllene
/ (E)-beta-Caryophyllene
CHEMBL445740
CHEMBL448700
2 / 3 / 7 No. 478 No. 38
C00002453 External link 512 Byakangelicin
/ (+)-Byakangelicin
CHEMBL508648
C434685
5 / 2 / 0 No. 579 No. 25
C00000300 External link 512 Seselin
/ Amyrolin
/ Seseline
CHEMBL71358
2 / 0 / 0 No. 750 No. 25
C00002648 External link 512 Gentisic acid
/ 2,5-Dihydroxybenzoic acid
CHEMBL1461
C010925
15 / 6 / 8 2 / 1 No. 817 No. 81
C00000803 External link 512 (-)-Limonene
CHEMBL15799
CHEMBL449062
7 / 21 / 48 No. 848 No. 35
C00002663 External link 512 2-Phenylethanol
/ Phenethyl alcohol
/ Phenylethyl alcohol
/ beta-Phenethyl alcohol
CHEMBL448500
D010626
2 / 1 / 1 No. 885
C00002729 External link 512 o-Coumaric acid
CHEMBL52564
C085894
17 / 6 / 17 No. 904 No. 6
C00002674 External link 512 Syringic acid
/ 4-Hydroxy-3,5-dimethoxybenzoic acid
CHEMBL1414
C001945
12 / 3 / 5 No. 1073
C00003051 External link 512 alpha-Phellandrene
CHEMBL455041
C005403
No. 1898 No. 35
C00003037 External link 512 (R)-Citronellal
/ (R)-3,7-Dimethyl-6-octenal
CHEMBL1081721
2 / 0 / 3 No. 1948 No. 34
C00003060 External link 512 alpha-Terpinene
No. 2468 No. 35
C00003061 External link 512 gamma-Terpinene
/ 1-Methyl-4-(1-methylethyl)-1,4-cyclohexadiene
CHEMBL449693
C018669
No. 2468 No. 35
C00011044 External link 512 (+)-Carene
CHEMBL506854
No. 2690 No. 35
C00010325 External link 512 Epoxylinalool
/ 3-Hydroxy-2,2,6-trimethyl-6-vinyltetrahydropyran
No. 2943
C00001418 External link 512 Indole
CHEMBL15844
C030374
13 / 5 / 6 6 / 0 No. 3673
C00000861 External link 512 Terpinolene
CHEMBL454697
C027009
1 / 0 No. 3725
C00001181 External link 512 Citramalic acid
No. 3837
C00001425 External link 512 Octopamine
CHEMBL53929
CHEMBL1160703
D009655
16 / 8 / 6 7 / 0 No. 4586
C00010866 External link 512 Thymyl methyl ether
/ 1-Isopropyl-2-methoxy-4-methylbenzene
No. 5608
C00001179 External link 512 Vitamin C
/ L-Ascorbate
/ L-Ascorbic acid
/ (+)-Ascorbic acid
CHEMBL196
CHEMBL1161421
D001205
104 / 58 / 50 254 / 98 No. 8774

Human Protein / Gene in interactions

227 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O75496 Geminin Unclassified protein C00000911 C00000954 C00000968 C00000982 C00000983 C00002488 C00002663 C00003776 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000968 C00000970 C00000982 C00000992 C00001179 C00001425 C00002488 C00003719 0 / 1
P83916 Chromobox protein homolog 1 Unclassified protein C00000968 C00000970 C00000983 C00000992 C00002453 C00002488 C00002648 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000968 C00000970 C00000982 C00000992 C00001179 C00001425 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00000968 C00000970 C00000982 C00000992 C00001179 C00001425 0 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00000968 C00000970 C00000982 C00000992 C00001179 C00001425 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00000968 C00000970 C00000982 C00000992 C00001179 C00001425 1 / 1
O00255 Menin Unclassified protein C00000954 C00000970 C00000982 C00000992 C00003110 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00000954 C00000970 C00000982 C00000992 C00003110 1 / 2
P00918 Carbonic anhydrase 2 Lyase C00001179 C00001418 C00002648 C00002674 C00002729 1 / 2
P10636 Microtubule-associated protein tau Unclassified protein C00000954 C00000968 C00000992 C00001179 4 / 3
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00000954 C00000968 C00000983 C00002453 1 / 0
Q9UNA4 DNA polymerase iota Enzyme C00000968 C00000970 C00000982 C00002648 0 / 0
P00915 Carbonic anhydrase 1 Lyase C00001418 C00002648 C00002674 C00002729 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00000803 C00000982 C00001179 C00003037 0 / 3
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00000911 C00000983 C00001425 C00003776 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00000911 C00000982 C00002488 C00003776 0 / 0
P22303 Acetylcholinesterase Hydrolase C00000968 C00000982 C00001179 1 / 0
P35372 Mu-type opioid receptor Opioid receptor C00000968 C00000982 C00001179 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00000968 C00000992 C00003723 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00000968 C00000982 C00000992 3 / 3
Q16790 Carbonic anhydrase 9 Lyase C00002648 C00002674 C00002729 0 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00000911 C00000970 C00000987 0 / 0
P22748 Carbonic anhydrase 4 Lyase C00001418 C00002674 C00002729 1 / 1
P28482 Mitogen-activated protein kinase 1 Erk C00000805 C00000968 C00001179 0 / 0
P04745 Alpha-amylase 1 Enzyme C00000968 C00000982 C00001179 0 / 0
P04062 Glucosylceramidase Enzyme C00000954 C00000982 C00002488 6 / 4
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 C00000968 C00000982 C00000992 4 / 4
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00000803 C00001179 C00001425 0 / 0
P43166 Carbonic anhydrase 7 Lyase C00002648 C00002674 C00002729 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00000970 C00000982 C00002663 1 / 1
Q99700 Ataxin-2 Unclassified protein C00000954 C00000968 C00001425 1 / 1
P41143 Delta-type opioid receptor Opioid receptor C00000968 C00000982 C00001179 0 / 0
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00000982 C00000983 C00002648 0 / 0
O43570 Carbonic anhydrase 12 Lyase C00002648 C00002674 C00002729 1 / 2
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00000803 C00000968 C00000982 0 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase C00002648 C00002674 C00002729 0 / 0
P23280 Carbonic anhydrase 6 Lyase C00001418 C00002674 C00002729 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00000968 C00000970 C00000992 0 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00000968 C00000982 C00001179 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00000911 C00001179 C00003776 2 / 3
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00000970 C00000992 C00001179 0 / 0
P02545 Prelamin-A/C Unclassified protein C00000803 C00000911 C00001179 11 / 10
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 C00000968 C00000982 C00000992 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00000805 C00000968 C00001425 3 / 2
P56817 Beta-secretase 1 A1A C00000300 C00002453 C00002488 0 / 0
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00000968 C00000982 0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00000954 C00000983 1 / 1
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00000982 C00002729 1 / 1
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00000970 C00001425 0 / 0
P14061 Estradiol 17-beta-dehydrogenase 1 Enzyme C00000968 C00000982 0 / 0
P22310 UDP-glucuronosyltransferase 1-4 Enzyme C00000982 C00000983 3 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00000803 C00000968 7 / 37
Q9Y6L6 Solute carrier organic anion transporter family member 1B1 Electrochemical transporter C00000982 C00000983 1 / 0
Q9Y251 Heparanase Enzyme C00000970 C00000983 0 / 0
P07451 Carbonic anhydrase 3 Lyase C00002674 C00002729 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00000954 C00000970 0 / 0
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00000982 C00000983 5 / 1
O94956 Solute carrier organic anion transporter family member 2B1 Unclassified protein C00000982 C00000983 0 / 0
P08183 Multidrug resistance protein 1 drug C00000982 C00000983 1 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00000954 C00000970 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00000968 C00002488 0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00001425 C00002729 0 / 0
P62158 Calmodulin Unclassified protein C00000970 C00000982 1 / 0
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00002488 C00002648 0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00001179 C00001425 0 / 0
P03372 Estrogen receptor NR3A1 C00000982 C00001179 1 / 1
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A C00000982 C00001179 0 / 0
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00000968 C00000982 2 / 0
P06746 DNA polymerase beta Enzyme C00000954 C00000970 0 / 0
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00002674 C00002729 0 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00000968 C00000982 5 / 3
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 C00000982 C00000983 2 / 2
P04150 Glucocorticoid receptor NR3C1 C00000982 C00001179 0 / 1
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00002674 C00002729 0 / 0
Q9NPD5 Solute carrier organic anion transporter family member 1B3 Electrochemical transporter C00000982 C00000983 1 / 0
P11308 Transcriptional regulator ERG Unclassified protein C00000970 C00000983 1 / 2
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00000954 C00000992 7 / 3
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00001179 C00002488 0 / 0
P03956 Interstitial collagenase M10A C00001179 C00002648 0 / 1
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00000954 C00002488 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00001179 C00001418 0 / 0
P15121 Aldose reductase Enzyme C00000982 C00002674 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00001179 C00002648 2 / 2
Q92731 Estrogen receptor beta NR3A2 C00000982 C00001179 0 / 1
P54855 UDP-glucuronosyltransferase 2B15 Enzyme C00000982 C00000983 0 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00000968 C00001425 0 / 0
P04406 Glyceraldehyde-3-phosphate dehydrogenase Enzyme C00000300 C00002488 0 / 0
P37059 Estradiol 17-beta-dehydrogenase 2 Enzyme C00000968 C00000982 0 / 0
Q9UGH3 Solute carrier family 23 member 2 Ascorbate C00001179 0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor C00001179 1 / 0
P17948 Vascular endothelial growth factor receptor 1 Vegfr C00001179 0 / 0
P04278 Sex hormone-binding globulin Secreted protein C00000982 0 / 0
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr C00000982 1 / 1
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00001179 0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor C00001179 1 / 1
Q8TDS4 Hydroxycarboxylic acid receptor 2 Hydroxycarboxylic acid receptor C00002729 0 / 0
P39748 Flap endonuclease 1 Enzyme C00000954 0 / 0
P16152 Carbonyl reductase [NADPH] 1 Enzyme C00000982 0 / 0
Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor Enzyme C00001179 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00000954 2 / 0
P27361 Mitogen-activated protein kinase 3 Erk C00001179 0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00000968 0 / 0
P46721 Solute carrier organic anion transporter family member 1A2 Unclassified protein C00000983 0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme C00000968 4 / 2
Q96KS0 Egl nine homolog 2 Enzyme C00001179 0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase C00001179 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00001179 0 / 0
P21917 D(4) dopamine receptor Dopamine receptor C00001179 0 / 0
P30988 Calcitonin receptor Calcitonin receptor C00001179 0 / 0
P35462 D(3) dopamine receptor Dopamine receptor C00001179 1 / 0
P17252 Protein kinase C alpha type Alpha C00001179 0 / 0
P46098 5-hydroxytryptamine receptor 3A NS C00001425 0 / 0
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor C00001179 0 / 0
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor C00001179 0 / 0
P29274 Adenosine receptor A2a Adenosine receptor C00001179 0 / 0
P25101 Endothelin-1 receptor Endothelin receptor C00001179 0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor C00001179 0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor C00001179 1 / 0
P29466 Caspase-1 C14 C00001179 0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor C00001179 0 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor C00001179 0 / 0
P08311 Cathepsin G S1A C00001179 0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00001179 1 / 0
O00519 Fatty-acid amide hydrolase 1 Enzyme C00003037 0 / 0
Q8N1Q1 Carbonic anhydrase 13 Lyase C00002729 0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor C00001179 0 / 0
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor C00001179 0 / 0
P14416 D(2) dopamine receptor Dopamine receptor C00001179 2 / 0
Q9Y253 DNA polymerase eta Enzyme C00000970 1 / 1
Q13315 Serine-protein kinase ATM Atypical serine/threonine protein kinase PIKK subfamily C00000968 1 / 4
P22894 Neutrophil collagenase M10A C00002648 0 / 0
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00001179 1 / 8
P13674 Prolyl 4-hydroxylase subunit alpha-1 Enzyme C00001179 0 / 0
Q9GZU7 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 Enzyme C00000970 0 / 0
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00001179 2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00001179 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00002453 1 / 0
P14679 Tyrosinase Oxidoreductase C00001179 4 / 2
P21554 Cannabinoid receptor 1 Cannabinoid receptor C00001179 0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin C00001179 2 / 0
Q9GZT9 Egl nine homolog 1 Enzyme C00001179 1 / 1
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00001179 5 / 9
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00001179 1 / 0
O75828 Carbonyl reductase [NADPH] 3 Enzyme C00000982 0 / 0
P21452 Substance-K receptor Neurokinin receptor C00001179 0 / 0
P55263 Adenosine kinase Enzyme C00001418 1 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor C00001179 0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor C00001179 3 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor C00001179 0 / 0
P04746 Pancreatic alpha-amylase Hydrolase C00001179 0 / 0
P18054 Arachidonate 12-lipoxygenase, 12S-type Enzyme C00000982 2 / 0
Q13133 Oxysterols receptor LXR-alpha NR1H3 C00000968 0 / 0
P41597 C-C chemokine receptor type 2 CC chemokine receptor C00001179 1 / 0
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor C00001179 0 / 0
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme C00001179 2 / 1
P24864 G1/S-specific cyclin-E1 Other cytosolic protein C00000982 0 / 2
Q16539 Mitogen-activated protein kinase 14 p38 C00001179 0 / 0
P33765 Adenosine receptor A3 Adenosine receptor C00001179 0 / 0
P08253 72 kDa type IV collagenase M10A C00002648 1 / 3
P08246 Neutrophil elastase S1A C00001179 2 / 1
P24385 G1/S-specific cyclin-D1 Other cytosolic protein C00002729 1 / 8
Q92887 Canalicular multispecific organic anion transporter 1 Unclassified protein C00000982 1 / 1
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00000968 2 / 2
O15118 Niemann-Pick C1 protein Unclassified protein C00000968 1 / 1
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00000805 0 / 0
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00001179 2 / 2
Q9HAW9 UDP-glucuronosyltransferase 1-8 Enzyme C00000982 0 / 0
P02647 Apolipoprotein A-I Unclassified protein C00000968 3 / 2
P11802 Cyclin-dependent kinase 4 CMGC serine/threonine protein kinase family C00002729 1 / 3
Q15078 Cyclin-dependent kinase 5 activator 1 REG serine/threonine protein kinase family C00001418 0 / 0
P08588 Beta-1 adrenergic receptor Adrenergic receptor C00001179 1 / 0
P24941 Cyclin-dependent kinase 2 Cdc2 C00000982 0 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00001179 0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor C00001179 0 / 0
Q00535 Cyclin-dependent kinase 5 Cdk5 C00001418 0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00001179 0 / 0
P25103 Substance-P receptor Neurokinin receptor C00001179 0 / 0
P25105 Platelet-activating factor receptor PAF receptor C00001179 0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor C00001179 0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr C00001179 0 / 0
P14618 Pyruvate kinase PKM Enzyme C00000968 0 / 0
P06241 Tyrosine-protein kinase Fyn Src C00001179 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00001425 2 / 0
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 C00001179 0 / 0
Q9HAW8 UDP-glucuronosyltransferase 1-10 Enzyme C00000982 0 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor C00001179 0 / 0
P61088 Ubiquitin-conjugating enzyme E2 N Enzyme C00000983 0 / 0
P08047 Transcription factor Sp1 Unclassified protein C00000992 0 / 0
P11309 Serine/threonine-protein kinase pim-1 Pim C00000992 0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor C00001179 0 / 0
Q99549 M-phase phosphoprotein 8 Unclassified protein C00001425 0 / 0
P17861 X-box-binding protein 1 Unclassified protein C00000954 1 / 0
P10275 Androgen receptor NR3C4 C00000982 3 / 4
P23975 Sodium-dependent noradrenaline transporter Norepinephrine C00001179 1 / 1
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00001179 0 / 0
P30542 Adenosine receptor A1 Adenosine receptor C00001179 0 / 0
P10828 Thyroid hormone receptor beta NR1A2 C00000803 3 / 1
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00001179 0 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 C00001179 1 / 1
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00001179 0 / 0
P06239 Tyrosine-protein kinase Lck Src C00001179 0 / 1
Q04760 Lactoylglutathione lyase Enzyme C00000982 0 / 0
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor C00001179 0 / 0
P08254 Stromelysin-1 M10A C00002648 1 / 0
P23141 Liver carboxylesterase 1 Enzyme C00001418 0 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor C00001179 0 / 0
P49888 Estrogen sulfotransferase Enzyme C00000982 0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine C00001179 1 / 0
P37173 TGF-beta receptor type-2 TKL dual-specificity kinase STKR type 2 subfamily C00000968 4 / 3
Q16637 Survival motor neuron protein Unclassified protein C00000968 4 / 1
O14980 Exportin-1 Unclassified protein C00002488 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002453 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00003719 0 / 0
Q9H6Z9 Egl nine homolog 3 Enzyme C00001179 0 / 0
P35367 Histamine H1 receptor Histamine receptor C00001179 0 / 0
P25021 Histamine H2 receptor Histamine receptor C00001179 0 / 0
P33527 Multidrug resistance-associated protein 1 drugs C00000982 0 / 0
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00001179 1 / 1
Q02410 Amyloid beta A4 precursor protein-binding family A member 1 Unclassified protein C00000970 0 / 0
Q00975 Voltage-dependent N-type calcium channel subunit alpha-1B N-TYPE C00000970 0 / 0
P05107 Integrin beta-2 Membrane receptor C00001418 1 / 1
P05362 Intercellular adhesion molecule 1 Adhesion C00001418 1 / 2
P20701 Integrin alpha-L Membrane receptor C00001418 0 / 0
P49840 Glycogen synthase kinase-3 alpha Gsk C00001418 0 / 0
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00001179 0 / 1
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00000803 0 / 0

370 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00000911 C00000968 C00000982 C00000983
C00001179 C00003723
581 BAX, BCL2L4 BCL2-associated X protein C00000968 C00000983 C00001179 C00003723
C00003776
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00000968 C00000982 C00000983 C00001179
C00003723
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00000968 C00000982 C00001179 C00003723
C00003776
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00000911 C00000982 C00000983 C00003719
847 CAT catalase (EC:1.11.1.6) C00000911 C00000968 C00001179 C00003776
3383 ICAM1, BB2, CD54, P3.58 intercellular adhesion molecule 1 C00000911 C00000970 C00000983 C00001179
6817 SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) C00000982 C00000992 C00001179 C00002648
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00000970 C00001179 C00003723 C00003776
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00000911 C00000970 C00000982 C00001179
595 CCND1, BCL1, D11S287E, PRAD1, U21B31 cyclin D1 C00000911 C00000968 C00001179 C00003776
196 AHR, bHLHe76 aryl hydrocarbon receptor C00000911 C00000968 C00000982 C00001418
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00000968 C00000982 C00000983 C00001179
1588 CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) C00000968 C00000982 C00001179
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00000982 C00000983 C00003723
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00000911 C00000968 C00001179
4363 ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 C00000968 C00000982 C00001179
5599 MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c mitogen-activated protein kinase 8 (EC:2.7.11.24) C00000911 C00000970 C00001179
6818 SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1) C00000982 C00000992 C00001179
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00000861 C00000911 C00000982
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00000970 C00000982 C00001179
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00002488 C00003723 C00003776
7412 VCAM1, CD106, INCAM-100 vascular cell adhesion molecule 1 C00000911 C00000970 C00001179
4318 MMP9, CLG4B, GELB, MANDP2, MMP-9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) C00000970 C00002488
5444 PON1, ESA, MVCD5, PON paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) C00000982 C00001179
2100 ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 estrogen receptor 2 (ER beta) C00000911 C00000982
2099 ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 estrogen receptor 1 C00000911 C00000982
1559 CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) C00000982 C00000983
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00000982 C00000983
6774 STAT3, APRF, HIES signal transducer and activator of transcription 3 (acute-phase response factor) C00000911 C00001179
54575 UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) C00000982 C00001179
4436 MSH2, COCA1, FCC1, HNPCC, HNPCC1, LCFS2 mutS homolog 2 C00000911 C00001179
4292 MLH1, COCA2, FCC2, HNPCC, HNPCC2, hMLH1 mutL homolog 1 C00000911 C00001179
54600 UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) C00000982 C00001179
7366 UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) C00000982 C00001179
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00000982 C00000983
405 ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 aryl hydrocarbon receptor nuclear translocator C00000982 C00001418
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00000911 C00000992
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00000970 C00001179
1432 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA mitogen-activated protein kinase 14 (EC:2.7.11.24) C00000911 C00001179
5601 MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK mitogen-activated protein kinase 9 (EC:2.7.11.24) C00000970 C00001179
10057 ABCC5, ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 C00000968 C00000982
5608 MAP2K6, MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3 mitogen-activated protein kinase kinase 6 (EC:2.7.12.2) C00000911 C00001179
1019 CDK4, CMM3, PSK-J3 cyclin-dependent kinase 4 (EC:2.7.11.22) C00000911 C00000968
10257 ABCC4, EST170205, MOAT-B, MOATB, MRP4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 C00000968 C00000982
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00000911 C00003723
6647 SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer superoxide dismutase 1, soluble (EC:1.15.1.1) C00001179
7402 UTRN, DMDL, DRP, DRP1 utrophin C00000968
118 ADD1, ADDA adducin 1 (alpha) C00000911
177 AGER, RAGE advanced glycosylation end product-specific receptor C00000911
367 AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM androgen receptor C00000911
571 BACH1, BACH-1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 C00000911
8314 BAP1, HUCEP-13, UCHL2 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (EC:3.4.19.12) C00000911
673 BRAF, B-RAF1, BRAF1, NS7, RAFB1 v-raf murine sarcoma viral oncogene homolog B (EC:2.7.11.1) C00000911
1027 CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 cyclin-dependent kinase inhibitor 1B (p27, Kip1) C00000968
898 CCNE1, CCNE cyclin E1 C00000911
983 CDK1, CDC2, CDC28A, P34CDC2 cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) C00000911
1020 CDK5, PSSALRE cyclin-dependent kinase 5 (EC:2.7.11.22) C00000911
1022 CDK7, CAK1, CDKN7, HCAK, MO15, STK1, p39MO15 cyclin-dependent kinase 7 (EC:2.7.11.23 2.7.11.22) C00000911
1025 CDK9, C-2k, CDC2L4, CTK1, PITALRE, TAK cyclin-dependent kinase 9 (EC:2.7.11.23 2.7.11.22) C00000911
1113 CHGA, CGA chromogranin A (parathyroid secretory protein 1) C00000911
1114 CHGB, SCG1 chromogranin B (secretogranin 1) C00000911
23418 CRB1, LCA8, RP12 crumbs homolog 1 (Drosophila) C00000911
1643 DDB2, DDBB, UV-DDB2 damage-specific DNA binding protein 2, 48kDa C00000911
1981 EIF4G1, EIF-4G1, EIF4F, EIF4G, EIF4GI, P220, PARK18 eukaryotic translation initiation factor 4 gamma, 1 C00000911
2176 FANCC, FA3, FAC, FACC Fanconi anemia, complementation group C C00000911
2188 FANCF, FAF Fanconi anemia, complementation group F C00000911
356 FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 Fas ligand (TNF superfamily, member 6) C00000911
2353 FOS, AP-1, C-FOS, p55 FBJ murine osteosarcoma viral oncogene homolog C00000911
2701 GJA4, CX37 gap junction protein, alpha 4, 37kDa C00000911
2702 GJA5, ATFB11, CX40 gap junction protein, alpha 5, 40kDa C00000911
2879 GPX4, GPx-4, GSHPx-4, MCSP, PHGPx, snGPx, snPHGPx glutathione peroxidase 4 (EC:1.11.1.12) C00000911
3146 HMGB1, HMG1, HMG3, SBP-1 high mobility group box 1 C00000911
3479 IGF1, IGF-I, IGF1A, IGFI insulin-like growth factor 1 (somatomedin C) C00000911
3480 IGF1R, CD221, IGFIR, IGFR, JTK13 insulin-like growth factor 1 receptor (EC:2.7.10.1) C00000911
3485 IGFBP2, IBP2, IGF-BP53 insulin-like growth factor binding protein 2, 36kDa C00000911
3713 IVL involucrin C00000911
3716 JAK1, JAK1A, JAK1B, JTK3 Janus kinase 1 (EC:2.7.10.2) C00000911
3725 JUN, AP-1, AP1, c-Jun jun proto-oncogene C00000911
3796 KIF2A, CDCBM3, HK2, KIF2 kinesin heavy chain member 2A C00000911
3838 KPNA2, IPOA1, QIP2, RCH1, SRP1alpha karyopherin alpha 2 (RAG cohort 1, importin alpha 1) C00000911
3949 LDLR, FH, FHC, LDLCQ2 low density lipoprotein receptor C00000911
3988 LIPA, CESD, LAL lipase A, lysosomal acid, cholesterol esterase (EC:3.1.1.13) C00000911
5604 MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1 mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) C00000911
5605 MAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2 mitogen-activated protein kinase kinase 2 (EC:2.7.12.2) C00000911
6416 MAP2K4, JNKK, JNKK1, MAPKK4, MEK4, MKK4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SERK1, SKK1 mitogen-activated protein kinase kinase 4 (EC:2.7.12.2) C00000911
1017 CDK2, p33(CDK2) cyclin-dependent kinase 2 (EC:2.7.11.22) C00000968
2539 G6PD, G6PD1 glucose-6-phosphate dehydrogenase (EC:1.1.1.49) C00002648
355 FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6 Fas cell surface death receptor C00000983
8772 FADD, MORT1 Fas (TNFRSF6)-associated via death domain C00000983
4247 MGAT2, CDG2A, CDGS2, GLCNACTII, GNT-II, GNT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (EC:2.4.1.143) C00000911
100507436 MICA, MIC-A, PERB11.1 MHC class I polypeptide-related sequence A C00000911
54576 UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) C00000982
54577 UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) C00000982
2956 MSH6, GTBP, GTMBP, HNPCC5, HSAP, p160 mutS homolog 6 C00000911
4842 NOS1, IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS nitric oxide synthase 1 (neuronal) (EC:1.14.13.39) C00000911
8021 NUP214, CAIN, CAN, D9S46E, N214, p250 nucleoporin 214kDa C00000911
5320 PLA2G2A, MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2 phospholipase A2, group IIA (platelets, synovial fluid) (EC:3.1.1.4) C00000911
5591 PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350 protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1) C00000911
10111 RAD50, NBSLD, RAD502, hRad50 RAD50 homolog (S. cerevisiae) C00000911
8045 RASSF7, C11orf13, HRAS1, HRC1 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 C00000911
5925 RB1, OSRC, RB, p105-Rb, pRb, pp110 retinoblastoma 1 C00000911
5962 RDX, DFNB24 radixin C00000911
6195 RPS6KA1, HU-1, MAPKAPK1A, RSK, RSK1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1) C00000911
6197 RPS6KA3, CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RSK2, S6K-alpha3, p90-RSK2, pp90RSK2 ribosomal protein S6 kinase, 90kDa, polypeptide 3 (EC:2.7.11.1) C00000911
6241 RRM2, R2, RR2, RR2M ribonucleotide reductase M2 (EC:1.17.4.1) C00000911
6401 SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2 selectin E C00000911
6414 SEPP1, SELP, SeP selenoprotein P, plasma, 1 C00000911
4088 SMAD3, HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3 SMAD family member 3 C00000911
8243 SMC1A, CDLS2, DXS423E, SB1.8, SMC1, SMC1L1, SMC1alpha, SMCB structural maintenance of chromosomes 1A C00000911
54658 UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) C00000982
7031 TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 trefoil factor 1 C00000911
7980 TFPI2, PP5, REF1, TFPI-2 tissue factor pathway inhibitor 2 C00000911
7039 TGFA, TFGA transforming growth factor, alpha C00000911
7097 TLR2, CD282, TIL4 toll-like receptor 2 C00000911
7099 TLR4, ARMD10, CD284, TLR-4, TOLL toll-like receptor 4 C00000911
6513 SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED solute carrier family 2 (facilitated glucose transporter), member 1 C00000982
7415 VCP, ALS14, IBMPFD, IBMPFD1, TERA, p97 valosin containing protein (EC:3.6.4.6) C00000911
7485 WRB, CHD5 tryptophan rich basic protein C00000911
7697 ZNF138, pHZ-32 zinc finger protein 138 C00000911
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00000992
7052 TGM2, G-ALPHA-h, GNAH, TG2, TGC transglutaminase 2 (EC:2.3.2.13) C00000992
4157 MC1R, CMM5, MSH-R, SHEP2 melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) C00001418
4159 MC3R, BMIQ9, MC3, MC3-R, OB20, OQTL melanocortin 3 receptor C00001418
4160 MC4R melanocortin 4 receptor C00001418
4161 MC5R, MC2 melanocortin 5 receptor C00001418
2180 ACSL1, ACS1, FACL1, FACL2, LACS, LACS1, LACS2 acyl-CoA synthetase long-chain family member 1 (EC:6.2.1.3) C00002488
1374 CPT1A, CPT1, CPT1-L, L-CPT1 carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21) C00002488
4313 MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) C00002488
6566 SLC16A1, HHF7, MCT, MCT1 solute carrier family 16 (monocarboxylate transporter), member 1 C00000982
4792 NFKBIA, IKBA, MAD-3, NFKBI nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha C00002488
5465 PPARA, NR1C1, PPAR, PPARalpha, hPPAR peroxisome proliferator-activated receptor alpha C00002488
3757 KCNH2, ERG1, HERG, HERG1, Kv11.1, LQT2, SQT1 potassium voltage-gated channel, subfamily H (eag-related), member 2 C00000982
249 ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1) C00000982
16 AARS, CMT2N alanyl-tRNA synthetase (EC:6.1.1.7) C00001179
19 ABCA1, ABC-1, ABC1, CERP, HDLDT1, TGD ATP-binding cassette, sub-family A (ABC1), member 1 C00001179
5243 ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) C00001179
1244 ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP ATP-binding cassette, sub-family C (CFTR/MRP), member 2 C00001179
59272 ACE2, ACEH angiotensin I converting enzyme 2 (EC:3.4.17.23) C00001179
59 ACTA2, AAT6, ACTSA, MYMY5 actin, alpha 2, smooth muscle, aorta C00001179
112 ADCY6, AC6 adenylate cyclase 6 (EC:4.6.1.1) C00001179
231 AKR1B1, ADR, ALDR1, ALR2, AR aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21) C00001179
248 ALPI, IAP alkaline phosphatase, intestinal (EC:3.1.3.1) C00001179
290 ANPEP, APN, CD13, GP150, LAP1, P150, PEPN alanyl (membrane) aminopeptidase (EC:3.4.11.2) C00001179
301 ANXA1, ANX1, LPC1 annexin A1 C00001179
335 APOA1 apolipoprotein A-I C00001179
338 APOB, FLDB, LDLCQ4 apolipoprotein B C00001179
55937 APOM, G3a, HSPC336, NG20, apo-M apolipoprotein M C00001179
351 APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2 amyloid beta (A4) precursor protein C00001179
360 AQP3, AQP-3, GIL aquaporin 3 (Gill blood group) C00001179
397 ARHGDIB, D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2 Rho GDP dissociation inhibitor (GDI) beta C00001179
440 ASNS, TS11 asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4) C00001179
467 ATF3 activating transcription factor 3 C00001179
9212 AURKB, AIK2, AIM-1, AIM1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5, aurkb-sv1, aurkb-sv2 aurora kinase B (EC:2.7.11.1) C00001179
27113 BBC3, JFY-1, JFY1, PUMA BCL2 binding component 3 C00001179
79370 BCL2L14, BCLG BCL2-like 14 (apoptosis facilitator) C00001179
632 BGLAP, BGP, OC, OCN bone gamma-carboxyglutamate (gla) protein C00001179
12095 C00001179
330 BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 baculoviral IAP repeat containing 3 C00001179
332 BIRC5, API4, EPR-1 baculoviral IAP repeat containing 5 C00001179
699 BUB1, BUB1A, BUB1L, hBUB1 BUB1 mitotic checkpoint serine/threonine kinase (EC:2.7.11.1) C00001179
768 CA9, CAIX, MN carbonic anhydrase IX (EC:4.2.1.1) C00001179
840 CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) C00001179
875 CBS, HIP4 cystathionine-beta-synthase (EC:4.2.1.22) C00001179
6347 CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF chemokine (C-C motif) ligand 2 C00001179
894 CCND2, KIAK0002 cyclin D2 C00001179
100133941 CD24, CD24A CD24 molecule C00001179
947 CD34 CD34 molecule C00001179
958 CD40, Bp50, CDW40, TNFRSF5, p50 CD40 molecule, TNF receptor superfamily member 5 C00001179
990 CDC6, CDC18L, HsCDC18, HsCDC6 cell division cycle 6 C00001179
728642 CDK11A, CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, PITSLRE, p58GTA cyclin-dependent kinase 11A (EC:2.7.11.22) C00001179
629 CFB, AHUS4, BF, BFD, CFAB, FB, FBI12, GBG, H2-Bf, PBF2 complement factor B (EC:3.4.21.47) C00001179
1080 CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1 cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) C00001179
11113 CIT, CRIK, STK21 citron (rho-interacting, serine/threonine kinase 21) (EC:2.7.11.1) C00001179
1264 CNN1, SMCC, Sm-Calp calponin 1, basic, smooth muscle C00001179
1270 CNTF, HCNTF ciliary neurotrophic factor C00001179
1277 COL1A1, OI4 collagen, type I, alpha 1 C00001179
1380 CR2, C3DR, CD21, CR, CVID7, SLEB9 complement component (3d/Epstein Barr virus) receptor 2 C00001179
1401 CRP, PTX1 C-reactive protein, pentraxin-related C00001179
1519 CTSO, CTSO1 cathepsin O (EC:3.4.22.42) C00001179
3627 CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1 chemokine (C-X-C motif) ligand 10 C00001179
6372 CXCL6, CKA-3, GCP-2, GCP2, SCYB6 chemokine (C-X-C motif) ligand 6 C00001179
4283 CXCL9, CMK, Humig, MIG, SCYB9, crg-10 chemokine (C-X-C motif) ligand 9 C00001179
643 CXCR5, BLR1, CD185, MDR15 chemokine (C-X-C motif) receptor 5 C00001179
79901 CYBRD1, CYB561A2, DCYTB, FRRS3 cytochrome b reductase 1 C00001179
1583 CYP11A1, CYP11A, CYPXIA1, P450SCC cytochrome P450, family 11, subfamily A, polypeptide 1 (EC:1.14.15.6) C00001179
1548 CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) C00001179
1556 CYP2B7P, CYP2B, CYP2B7, CYP2B7P1 cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene C00001179
1571 CYP2E1, CPE1, CYP2E, P450-J, P450C2E cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) C00001179
22943 DKK1, DKK-1, SK dickkopf WNT signaling pathway inhibitor 1 C00001179
9787 DLGAP5, DLG7, HURP discs, large (Drosophila) homolog-associated protein 5 C00001179
54431 DNAJC10, ERdj5, JPDI, MTHr, PDIA19 DnaJ (Hsp40) homolog, subfamily C, member 10 C00001179
1773 DNASE1, DNL1, DRNI deoxyribonuclease I (EC:3.1.21.1) C00001179
1803 DPP4, ADABP, ADCP2, CD26, DPPIV, TP103 dipeptidyl-peptidase 4 (EC:3.4.14.5) C00001179
1906 EDN1, ET1, HDLCQ7, PPET1 endothelin 1 C00001179
1908 EDN3, ET-3, ET3, HSCR4, PPET3, WS4B endothelin 3 C00001179
1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA epidermal growth factor receptor (EC:2.7.10.1) C00001179
112399 EGLN3, HIFP4H3, HIFPH3, PHD3 egl-9 family hypoxia-inducible factor 3 (EC:1.14.11.29) C00001179
8894 EIF2S2, EIF2, EIF2B, EIF2beta, PPP1R67, eIF-2-beta eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa C00001179
8661 EIF3A, EIF3, EIF3S10, P167, TIF32, eIF3-p170, eIF3-theta, p180, p185 eukaryotic translation initiation factor 3, subunit A C00001179
8343525 C00001179
1973 EIF4A1, DDX2A, EIF-4A, EIF4A, eIF-4A-I, eIF4A-I eukaryotic translation initiation factor 4A1 (EC:3.6.4.13) C00001179
2012 EMP1, CL-20, EMP-1, TMP epithelial membrane protein 1 C00001179
2014 EMP3, YMP epithelial membrane protein 3 C00001179
2034 EPAS1, ECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73 endothelial PAS domain protein 1 C00001179
2052 EPHX1, EPHX, EPOX, HYL1, MEH epoxide hydrolase 1, microsomal (xenobiotic) (EC:3.3.2.9) C00001179
2053 EPHX2, CEH, SEH epoxide hydrolase 2, cytoplasmic (EC:3.3.2.10 3.1.3.76) C00001179
2058 EPRS, EARS, GLUPRORS, PARS, QARS, QPRS glutamyl-prolyl-tRNA synthetase (EC:6.1.1.15 6.1.1.17) C00001179
2172 FABP6, I-15P, I-BABP, I-BALB, I-BAP, ILBP, ILBP3, ILLBP fatty acid binding protein 6, ileal C00001179
2321 FLT1, FLT, FLT-1, VEGFR-1, VEGFR1 fms-related tyrosine kinase 1 (EC:2.7.10.1) C00001179
2326 FMO1 flavin containing monooxygenase 1 (EC:1.14.13.8) C00001179
2330 FMO5 flavin containing monooxygenase 5 (EC:1.14.13.8) C00001179
2335 FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF fibronectin 1 C00001179
2302 FOXJ1, FKHL13, HFH-4, HFH4 forkhead box J1 C00001179
2534 FYN, SLK, SYN, p59-FYN FYN oncogene related to SRC, FGR, YES (EC:2.7.10.2) C00001179
2535 FZD2, Fz2, fz-2, fzE2, hFz2 frizzled family receptor 2 C00001179
50486 G0S2, RP1-28O10.2 G0/G1switch 2 C00001179
2580 GAK, DNAJ26, DNAJC26 cyclin G associated kinase (EC:2.7.11.1) C00001179
2617 GARS, CMT2D, DSMAV, GlyRS, HMN5, SMAD1 glycyl-tRNA synthetase (EC:6.1.1.14) C00001179
2623 GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT GATA binding protein 1 (globin transcription factor 1) C00001179
2674 GFRA1, GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1 GDNF family receptor alpha 1 C00001179
2744 GLS, AAD20, GAC, GAM, GLS1, KGA glutaminase (EC:3.5.1.2) C00001179
2876 GPX1, GPXD, GSHPX1 glutathione peroxidase 1 (EC:1.11.1.9) C00001179
2877 GPX2, GI-GPx, GPRP, GPRP-2, GPx-2, GPx-GI, GSHPX-GI, GSHPx-2 glutathione peroxidase 2 (gastrointestinal) (EC:1.11.1.9) C00001179
2936 GSR glutathione reductase (EC:1.8.1.7) C00001179
2938 GSTA1, GST2, GSTA1-1, GTH1 glutathione S-transferase alpha 1 (EC:2.5.1.18) C00001179
2944 GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1 glutathione S-transferase mu 1 (EC:2.5.1.18) C00001179
2952 GSTT1 glutathione S-transferase theta 1 (EC:2.5.1.18) C00001179
2965 GTF2H1, BTF2, P62, TFB1, TFIIH general transcription factor IIH, polypeptide 1, 62kDa C00001179
3014 H2AFX, H2A.X, H2A/X, H2AX H2A histone family, member X C00001179
9843 HEPH, CPL hephaestin C00001179
9709 HERPUD1, HERP, Mif1, SUP homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 C00001179
3091 HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) C00001179
3098 HK1, HK1-ta, HK1-tb, HK1-tc, HKD, HKI, HMSNR, HXK1 hexokinase 1 (EC:2.7.1.1) C00001179
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00001179
3240 HP, BP, HP2ALPHA2, HPA1S haptoglobin C00001179
3283 HSD3B1, 3BETAHSD, HSD3B, HSDB3, HSDB3A, I, SDR11E1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (EC:1.1.1.145 5.3.3.1) C00001179
3303 HSPA1A, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1 heat shock 70kDa protein 1A C00001179
3309 HSPA5, BIP, GRP78, MIF2 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) C00001179
3313 HSPA9, CSA, GRP-75, GRP75, HSPA9B, MOT, MOT2, MTHSP75, PBP74 heat shock 70kDa protein 9 (mortalin) C00001179
3315 HSPB1, CMT2F, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27 heat shock 27kDa protein 1 C00001179
3347 HTN3, HIS2, HTN2, HTN5 histatin 3 C00001179
3376 IARS, IARS1, ILERS, ILRS, IRS, PRO0785 isoleucyl-tRNA synthetase (EC:6.1.1.5) C00001179
8870 IER3, DIF-2, DIF2, GLY96, IEX-1, IEX-1L, IEX1, PRG1 immediate early response 3 C00001179
3488 IGFBP5, IBP5 insulin-like growth factor binding protein 5 C00001179
10320 IKZF1, Hs.54452, IK1, IKAROS, LYF1, PRO0758, ZNFN1A1, hIk-1 IKAROS family zinc finger 1 (Ikaros) C00001179
8644 AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357) C00000982
3745 KCNB1, DRK1, KV2.1, h-DRK1 potassium voltage-gated channel, Shab-related subfamily, member 1 C00001179
3791 KDR, CD309, FLK1, VEGFR, VEGFR2 kinase insert domain receptor (a type III receptor tyrosine kinase) (EC:2.7.10.1) C00001179
9493 KIF23, CHO1, KNSL5, MKLP-1, MKLP1 kinesin family member 23 C00001179
3932 LCK, LSK, YT16, p56lck, pp58lck lymphocyte-specific protein tyrosine kinase (EC:2.7.10.2) C00001179
3956 LGALS1, GAL1, GBP lectin, galactoside-binding, soluble, 1 C00001179
4017 LOXL2, LOR2, WS9-14 lysyl oxidase-like 2 (EC:1.4.3.-) C00001179
4067 LYN, JTK8, p53Lyn, p56Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (EC:2.7.10.2) C00001179
23764 MAFF, U-MAF, hMafF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F C00001179
10892 MALT1, IMD12, MLT, MLT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 (EC:3.4.22.-) C00001179
5606 MAP2K3, MAPKK3, MEK3, MKK3, PRKMK3, SAPKK-2, SAPKK2 mitogen-activated protein kinase kinase 3 (EC:2.7.12.2) C00001179
4217 MAP3K5, ASK1, MAPKKK5, MEKK5 mitogen-activated protein kinase kinase kinase 5 (EC:2.7.11.25) C00001179
1645 AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112) C00000982
4173 MCM4, CDC21, CDC54, NKCD, NKGCD, P1-CDC21, hCdc21 minichromosome maintenance complex component 4 (EC:3.6.4.12) C00001179
4224 MEP1A, PPHA meprin A, alpha (PABA peptide hydrolase) (EC:3.4.24.18) C00001179
4233 MET, AUTS9, HGFR, RCCP2, c-Met met proto-oncogene (EC:2.7.10.1) C00001179
4288 MKI67, KIA, MIB-1 marker of proliferation Ki-67 C00001179
4312 MMP1, CLG, CLGN matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) C00001179
4316 MMP7, MMP-7, MPSL1, PUMP-1 matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23) C00001179
4353 MPO myeloperoxidase (EC:1.11.2.2) C00001179
4485 MST1, D3F15S2, DNF15S2, HGFL, MSP, NF15S2 macrophage stimulating 1 (hepatocyte growth factor-like) C00001179
11223 MST1L, BRF-1, D1F15S1A, MSPL-7, MSPL7, MST1P9, MSTP7, MSTP9 macrophage stimulating 1-like C00001179
4504 MT3, GIF, GIFB, GRIF, ZnMT3 metallothionein 3 C00001179
10797 MTHFD2, NMDMC methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (EC:3.5.4.9 1.5.1.15) C00001179
4605 MYBL2, B-MYB, BMYB v-myb avian myeloblastosis viral oncogene homolog-like 2 C00001179
4640 MYO1A, BBMI, DFNA48, MIHC, MYHL myosin IA C00001179
4677 NARS, ASNRS, NARS1 asparaginyl-tRNA synthetase (EC:6.1.1.22) C00001179
10397 NDRG1, CAP43, CMT4D, DRG-1, DRG1, GC4, HMSNL, NDR1, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5 N-myc downstream regulated 1 C00001179
4780 NFE2L2, NRF2 nuclear factor, erythroid 2-like 2 C00001179
4800 NFYA, CBF-A, CBF-B, HAP2, NF-YA nuclear transcription factor Y, alpha C00001179
4814 NINJ1, NIN1, NINJURIN ninjurin 1 C00001179
7080 NKX2-1, BCH, BHC, NK-2, NKX2.1, NKX2A, TEBP, TITF1, TTF-1, TTF1 NK2 homeobox 1 C00001179
4830 NME1, AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1 NME/NM23 nucleoside diphosphate kinase 1 (EC:2.7.4.6) C00001179
4843 NOS2, HEP-NOS, INOS, NOS, NOS2A nitric oxide synthase 2, inducible (EC:1.14.13.39) C00001179
4846 NOS3, ECNOS, eNOS nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) C00001179
2908 NR3C1, GCCR, GCR, GR, GRL nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) C00001179
8013 NR4A3, CHN, CSMF, MINOR, NOR1, TEC nuclear receptor subfamily 4, group A, member 3 C00001179
4973 OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1 oxidized low density lipoprotein (lectin-like) receptor 1 C00001179
10956 OS9, ERLEC2, OS-9 osteosarcoma amplified 9, endoplasmic reticulum lectin C00001179
8974 P4HA2 prolyl 4-hydroxylase, alpha polypeptide II (EC:1.14.11.2) C00001179
54681 P4HTM, EGLN4, HIFPH4, P4H-TM, PH-4, PH4, PHD4 prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) C00001179
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) C00001179
5106 PCK2, PEPCK, PEPCK-M, PEPCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) (EC:4.1.1.32) C00001179
64714 PDIA2, PDA2, PDI, PDIP, PDIR protein disulfide isomerase family A, member 2 (EC:5.3.4.1) C00001179
2923 PDIA3, ER60, ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC protein disulfide isomerase family A, member 3 (EC:5.3.4.1) C00001179
26227 PHGDH, 3-PGDH, 3PGDH, PDG, PGAD, PGD, PGDH, SERA phosphoglycerate dehydrogenase (EC:1.1.1.95) C00001179
22822 PHLDA1, DT1P1B11, PHRIP, TDAG51 pleckstrin homology-like domain, family A, member 1 C00001179
7262 PHLDA2, BRW1C, BWR1C, HLDA2, IPL, TSSC3 pleckstrin homology-like domain, family A, member 2 C00001179
11145 PLA2G16, AdPLA, H-REV107-1, HRASLS3, HREV107, HREV107-1, HREV107-3, HRSL3 phospholipase A2, group XVI (EC:3.1.1.4 3.1.1.32) C00001179
5340 PLG plasminogen (EC:3.4.21.7) C00001179
5347 PLK1, PLK, STPK13 polo-like kinase 1 (EC:2.7.11.21) C00001179
5366 PMAIP1, APR, NOXA phorbol-12-myristate-13-acetate-induced protein 1 C00001179
5376 PMP22, CMT1A, CMT1E, DSS, GAS-3, HMSNIA, HNPP, Sp110 peripheral myelin protein 22 C00001179
5445 PON2 paraoxonase 2 (EC:3.1.1.2 3.1.1.81) C00001179
5460 POU5F1, OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4 POU class 5 homeobox 1 C00001179
10891 PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha C00001179
5588 PRKCQ, PRKCT, nPKC-theta protein kinase C, theta (EC:2.7.11.13) C00001179
38175 C00001179
5702 PSMC3, TBP1 proteasome (prosome, macropain) 26S subunit, ATPase, 3 C00001179
5865 RAB3B RAB3B, member RAS oncogene family C00001179
5870 RAB6A, RAB6 RAB6A, member RAS oncogene family C00001179
5879 RAC1, Rac-1, TC-25, p21-Rac1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) C00001179
5889 RAD51C, BROVCA3, FANCO, R51H3, RAD51L2 RAD51 paralog C C00001179
25788 RAD54B, RDH54 RAD54 homolog B (S. cerevisiae) C00001179
1827 RCAN1, ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1 regulator of calcineurin 1 C00001179
860 RUNX2, AML3, CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, PEA2aA, PEBP2aA runt-related transcription factor 2 C00001179
795 S100G, CABP, CABP1, CABP9K, CALB3 S100 calcium binding protein G C00001179
5055 SERPINB2, HsT1201, PAI, PAI-2, PAI2, PLANH2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 C00001179
83667 SESN2, HI95, SES2, SEST2 sestrin 2 C00001179
6439 SFTPB, PSP-B, SFTB3, SFTP3, SMDP1, SP-B surfactant protein B C00001179
6472 SHMT2, GLYA, SHMT serine hydroxymethyltransferase 2 (mitochondrial) (EC:2.1.2.1) C00001179
6476 SI sucrase-isomaltase (alpha-glucosidase) (EC:3.2.1.10 3.2.1.48) C00001179
4891 SLC11A2, DCT1, DMT1, NRAMP2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 C00001179
10864 SLC22A7, NLT, OAT2 solute carrier family 22 (organic anion transporter), member 7 C00001179
9963 SLC23A1, SLC23A2, SVCT1, YSPL3 solute carrier family 23 (ascorbic acid transporter), member 1 C00001179
9962 SLC23A2, NBTL1, SLC23A1, SVCT2, YSPL2 solute carrier family 23 (ascorbic acid transporter), member 2 C00001179
79677 SMC6, SMC-6, SMC6L1, hSMC6 structural maintenance of chromosomes 6 C00001179
54205 CYCS, CYC, HCS, THC4 cytochrome c, somatic C00000968
6648 SOD2, IPOB, MNSOD, MVCD6 superoxide dismutase 2, mitochondrial (EC:1.15.1.1) C00001179
6657 SOX2, ANOP3, MCOPS3 SRY (sex determining region Y)-box 2 C00001179
6667 SP1 Sp1 transcription factor C00001179
6670 SP3, SPR2 Sp3 transcription factor C00001179
6671 SP4, HF1B, SPR-1 Sp4 transcription factor C00001179
6678 SPARC, ON secreted protein, acidic, cysteine-rich (osteonectin) C00001179
6696 SPP1, BNSP, BSPI, ETA-1, OPN secreted phosphoprotein 1 C00001179
6772 STAT1, CANDF7, ISGF-3, STAT91 signal transducer and activator of transcription 1, 91kDa C00001179
9262 STK17B, DRAK2 serine/threonine kinase 17b (EC:2.7.11.1) C00001179
20888 C00001179
6822 SULT2A1, DHEA-ST, DHEAS, HST, ST2, ST2A1, ST2A3, STD, hSTa sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 (EC:2.8.2.14) C00001179
6876 TAGLN, SM22, SMCC, TAGLN1, WS3-10 transgelin C00001179
6897 TARS, ThrRS threonyl-tRNA synthetase (EC:6.1.1.3) C00001179
6901 TAZ, BTHS, CMD3A, EFE, EFE2, G4.5, LVNCX, Taz1 tafazzin C00001179
7018 TF, PRO1557, PRO2086, TFQTL1 transferrin C00001179
7032 TFF2, SML1, SP trefoil factor 2 C00001179
7040 TGFB1, CED, DPD1, LAP, TGFB, TGFbeta transforming growth factor, beta 1 C00001179
7076 TIMP1, CLGI, EPA, EPO, HCI, TIMP TIMP metallopeptidase inhibitor 1 C00001179
4071 TM4SF1, H-L6, L6, M3S1, TAAL6 transmembrane 4 L six family member 1 C00001179
164656 TMPRSS6, IRIDA transmembrane protease, serine 6 C00001179
4982 TNFRSF11B, OCIF, OPG, TR1 tumor necrosis factor receptor superfamily, member 11b C00001179
8743 TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL tumor necrosis factor (ligand) superfamily, member 10 C00001179
11257 TP53TG1, LINC00096, NCRNA00096, P53TG1, P53TG1-D, TP53AP1 TP53 target 1 (non-protein coding) C00001179
57761 TRIB3, C20orf97, NIPK, SINK, SKIP3, TRB3 tribbles pseudokinase 3 C00001179
9322 TRIP10, CIP4, HSTP, STOT, STP thyroid hormone receptor interactor 10 C00001179
7224 TRPC5, TRP5 transient receptor potential cation channel, subfamily C, member 5 C00001179
7299 TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 tyrosinase (EC:1.14.18.1) C00001179
7319 UBE2A, HHR6A, MRXS30, MRXSN, RAD6A, UBC2 ubiquitin-conjugating enzyme E2A (EC:6.3.2.19) C00001179
7428 VHL, HRCA1, RCA1, VHL1, pVHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase C00001179
55350 VNN3, HSA238982 vanin 3 C00001179
7443 VRK1, PCH1, PCH1A vaccinia related kinase 1 (EC:2.7.11.1) C00001179
7453 WARS, GAMMA-2, IFI53, IFP53 tryptophanyl-tRNA synthetase (EC:6.1.1.2) C00001179
10352 WARS2, TrpRS tryptophanyl tRNA synthetase 2, mitochondrial (EC:6.1.1.2) C00001179
25937 WWTR1, TAZ WW domain containing transcription regulator 1 C00001179
7512 XPNPEP2, APP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound (EC:3.4.11.9) C00001179
7515 XRCC1, RCC X-ray repair complementing defective repair in Chinese hamster cells 1 C00001179
7718 ZNF165, CT53, LD65, ZSCAN7 zinc finger protein 165 C00001179
3569 IL6, BSF2, HGF, HSF, IFNB2, IL-6 interleukin 6 (interferon, beta 2) C00000970
153 ADRB1, ADRB1R, B1AR, BETA1AR, RHR adrenoceptor beta 1 C00001425
154 ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR adrenoceptor beta 2, surface C00001425
155 ADRB3, BETA3AR adrenoceptor beta 3 C00001425
6530 SLC6A2, NAT1, NET, NET1, SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 2 C00001425
6531 SLC6A3, DAT, DAT1, PKDYS solute carrier family 6 (neurotransmitter transporter), member 3 C00001425
6532 SLC6A4, 5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT solute carrier family 6 (neurotransmitter transporter), member 4 C00001425
134864 TAAR1, RP11-295F4.9, TA1, TAR1, TRAR1 trace amine associated receptor 1 C00001425
598 BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS BCL2-like 1 C00003776

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (151)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#103780 Alcohol dependence P08172
P14416
P31645
#105200 Amyloidosis, familial visceral P02647
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
#208900 Ataxia-telangiectasia; at Q13315
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#614490 Blood group, junior system; jr Q9UNQ0
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
%606641 Body mass index; bmi P37231
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#300615 Brunner syndrome P21397
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#609338 Carotid intimal medial thickness 1 P37231
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#614331 Colorectal cancer, hereditary nonpolyposis, type 6; hnpcc6 P37173
#114500 Colorectal cancer; crc P18054
P84022
#614466 Coronary heart disease, susceptibility to, 6; chds6 P08254
#218800 Crigler-najjar syndrome, type i P22309
P22310
#606785 Crigler-najjar syndrome, type ii P22309
P22310
#162800 Cyclic neutropenia P08246
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#237500 Dubin-johnson syndrome; djs Q92887
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#609820 Erythrocytosis, familial, 3; ecyt3 Q9GZT9
#133239 Esophageal cancer P04637
P18054
P37173
#615363 Estrogen resistance; estrr P03372
#612219 Ewing sarcoma; es P11308
#600274 Frontotemporal dementia; ftd P10636
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#143500 Gilbert syndrome P22309
P22310
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#137800 Glioma susceptibility 1; glm1 O75874
P04626
P37231
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#237450 Hyperbilirubinemia, rotor type; hblrr Q9NPD5
Q9Y6L6
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#143860 Hyperchlorhidrosis, isolated O43570
#614300 Hypermethioninemia due to adenosine kinase deficiency P55263
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#604091 Hypoalphalipoproteinemia, primary P02647
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#612244 Inflammatory bowel disease 13; ibd13 P08183
#603932 Intervertebral disc disease; idd P14780
#601626 Leukemia, acute myeloid; aml P36888
#116920 Leukocyte adhesion deficiency, type i; lad P05107
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#610168 Loeys-dietz syndrome, type 1b; lds1b P37173
#610380 Loeys-dietz syndrome, type 2b; lds2b P37173
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
P04637
#612371 Major affective disorder 7; mafd7 P17861
#608516 Major depressive disorder; mdd P08172
#611162 Malaria, susceptibility to P05362
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#174800 Mccune-albright syndrome; mas P63092
#609048 Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 P11802
#300705 Mental retardation, x-linked 17; mrx17 Q99714
%300852 Mental retardation, x-linked 88; mrx88 P50052
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#126200 Multiple sclerosis, susceptibility to; ms P08575
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#254500 Myeloma, multiple P24385
#159900 Myoclonic dystonia P14416
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#257220 Niemann-pick disease, type c1; npc1 O15118
#601665 Obesity P32245
P37231
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#166350 Osseous heteroplasia, progressive; poh P63092
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260500 Papilloma of choroid plexus; cpp P04637
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#604229 Peters anomaly Q16678
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#607276 Resting heart rate, variation in P08588
#275210 Restrictive dermopathy, lethal P02545
#600852 Retinitis pigmentosa 17; rp17 P22748
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#205400 Tangier disease; tgd P02647
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#190300 Tremor, hereditary essential, 1; etm1 P35462
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#614916 Ventricular tachycardia, catecholaminergic polymorphic, 4; cpvt4 P62158
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#610379 West nile virus, susceptibility to P51681
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253
#112100 Yt blood group antigen P22303

KEGG DISEASE (124)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
P04637 (marker)
Q16790 (marker)
H00016 Oral cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
P24385 (related)
P24385 (marker)
H00017 Esophageal cancer P00533 (related)
P04637 (related)
P04637 (marker)
P24385 (related)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
P04637 (related)
P24864 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
P04637 (related)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
P04637 (related)
P08253 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
P11802 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
P11802 (related)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
P24385 (related)
P24385 (marker)
P24864 (related)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
P37231 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00845 Familial amyloidosis P02647 (related)
H00930 Hypoalphalipoproteinemia P02647 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
P04637 (related)
Q92731 (marker)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
P11511 (related)
H00019 Pancreatic cancer P04626 (related)
P04637 (related)
P04637 (marker)
H00027 Ovarian cancer P04626 (related)
P04637 (related)
P38398 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
P04637 (related)
P24385 (related)
P38398 (related)
H00046 Cholangiocarcinoma P04626 (related)
P04637 (related)
P35354 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
Q13315 (related)
H00006 Hairy-cell leukemia P04637 (related)
P24385 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
P24385 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
P37173 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P08253 (related)
P14780 (related)
P35354 (related)
H00029 Vulvar cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
P37231 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
P11802 (related)
P14679 (marker)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00044 Cancer of the anal canal P04637 (related)
H00047 Gallbladder cancer P04637 (related)
P24385 (marker)
H00048 Hepatocellular carcinoma P04637 (related)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00099 Leukocyte adhesion deficiency (LAD) P05107 (related)
H00083 Allograft rejection P05362 (related)
H00080 Systemic lupus erythematosus P05362 (marker)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00079 Asthma P07550 (related)
H00100 Neutropenic disorders P08246 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00024 Prostate cancer P10275 (related)
P11308 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00035 Ewing's sarcoma P11308 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00794 Aromatase excess syndrome P11511 (related)
H01205 Coumarin resistance P11712 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00548 Brunner syndrome P21397 (related)
H00208 Hyperbilirubinemia P22309 (related)
Q92887 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00559 von Hippel-Lindau syndrome P24385 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
H00800 Loeys-Dietz syndrome (LDS) P37173 (related)
H00801 Familial thoracic aortic aneurysm and dissection (TAAD) P37173 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00192 Xanthinuria P47989 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
Q99714 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00064 Ataxia telangiectasia (AT) Q13315 (related)
H00094 DNA repair defects Q13315 (related)
H00848 Ataxia with ocular apraxia (AOA) Q13315 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00236 Congenital polycythemia Q9GZT9 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

121 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D056486 Drug-Induced Liver Injury C00000982
C00000983
C00000968
C00000911
C00003722
C00001179
C00000970
D009369 Neoplasms C00000982
C00000911
C00001179
D058186 Acute Kidney Injury C00000983
C00001179
C00000970
D007674 Kidney Diseases C00000982
C00000911
C00001179
D011471 Prostatic Neoplasms C00000911
C00001179
D064420 Drug-Related Side Effects and Adverse Reactions C00000982
C00001179
D009202 Cardiomyopathies C00000982
C00001179
D000647 Amnesia C00000982
C00001179
D006965 Hyperplasia C00000911
C00001179
D055371 Acute Lung Injury C00001179
C00000970
D009374 Neoplasms, Experimental C00000982
C00001179
D008171 Lung Diseases C00001179
C00000970
D009203 Myocardial Infarction C00000983
C00001179
D006943 Hyperglycemia C00000911
C00002488
D053040 Nephrolithiasis C00001179
D006461 Hemolysis C00002648
D000230 Adenocarcinoma C00000968
D003110 Colonic Neoplasms C00000968
D002583 Uterine Cervical Neoplasms C00000983
D008107 Liver Diseases C00000982
D007248 Infertility, Male C00000911
D007249 Inflammation C00000911
D020258 Neurotoxicity Syndromes C00000911
D008106 Liver Cirrhosis, Experimental C00000982
D012878 Skin Neoplasms C00000911
D013733 Testicular Diseases C00000911
D014178 Translocation, Genetic C00000911
D015431 Weight Loss C00000911
C538231 Adenocarcinoma of lung C00002488
D003920 Diabetes Mellitus C00002488
D009361 Neoplasm Invasiveness C00002488
D001932 Brain Neoplasms C00000982
D000740 Anemia C00001179
D018798 Anemia, Iron-Deficiency C00001179
D000749 Anemia, Megaloblastic C00001179
D000756 Anemia, Sideroblastic C00001179
D001206 Ascorbic Acid Deficiency C00001179
D001424 Bacterial Infections C00001179
D001766 Blindness C00001179
D001847 Bone Diseases C00001179
D001927 Brain Diseases C00001179
D002545 Brain Ischemia C00001179
D001943 Breast Neoplasms C00001179
D002277 Carcinoma C00001179
D006528 Carcinoma, Hepatocellular C00001179
D018376 Cardiovascular Abnormalities C00001179
D002318 Cardiovascular Diseases C00001179
D002375 Catalepsy C00001179
D002386 Cataract C00001179
D002471 Cell Transformation, Neoplastic C00001179
D002607 Charcot-Marie-Tooth Disease C00001179
D002869 Chromosome Aberrations C00001179
D003139 Common Cold C00001179
D020918 Complex Regional Pain Syndromes C00001179
D003327 Coronary Disease C00001179
D003681 Dehydration C00001179
D003924 Diabetes Mellitus, Type 2 C00001179
D003928 Diabetic Nephropathies C00001179
D003930 Diabetic Retinopathy C00001179
D062787 Drug Overdose C00001179
C538011 Eales disease C00001179
D004890 Erythema C00001179
D005221 Fatigue C00001179
D006029 Glycosuria C00001179
D006130 Growth Disorders C00001179
D006212 Hallucinations C00001179
D006330 Heart Defects, Congenital C00001179
D006548 Hernia, Diaphragmatic C00001179
D015658 HIV Infections C00001179
D006959 Hyperoxaluria C00001179
D006973 Hypertension C00001179
D006977 Hypertension, Renal C00001179
D007022 Hypotension C00001179
D007037 Hypothyroidism C00001179
146850 IMMUNE SUPPRESSION C00001179
D007683 Kidney Tubular Necrosis, Acute C00001179
D007859 Learning Disorders C00001179
D007945 Leukemia, Lymphoid C00001179
D008103 Liver Cirrhosis C00001179
D008114 Liver Neoplasms, Experimental C00001179
D001862 Bone Resorption C00003719
D008175 Lung Neoplasms C00001179
D020149 Manganese Poisoning C00001179
D008630 Mercury Poisoning C00001179
D048629 Micronuclei, Chromosome-Defective C00001179
D009120 Muscle Cramp C00001179
D009135 Muscular Diseases C00001179
D009325 Nausea C00001179
D009336 Necrosis C00001179
D009395 Nephritis, Interstitial C00001179
D003877 Dermatitis, Contact C00000805
D009410 Nerve Degeneration C00001179
D009422 Nervous System Diseases C00001179
D009765 Obesity C00001179
D009845 Oligospermia C00001179
D010149 Pain, Postoperative C00001179
D010212 Papilloma C00001179
D016491 Peripheral Vascular Diseases C00001179
D011041 Poisoning C00001179
D011230 Precancerous Conditions C00001179
D011507 Proteinuria C00001179
D011561 Pseudoxanthoma Elasticum C00001179
D011605 Psychoses, Substance-Induced C00001179
D011654 Pulmonary Edema C00001179
D011657 Pulmonary Eosinophilia C00001179
D011658 Pulmonary Fibrosis C00001179
D051437 Renal Insufficiency C00001179
D012174 Retinitis Pigmentosa C00001179
D012614 Scurvy C00001179
D012640 Seizures C00001179
D012871 Skin Diseases C00001179
D013226 Status Epilepticus C00001179
D013274 Stomach Neoplasms C00001179
D013276 Stomach Ulcer C00001179
D020521 Stroke C00001179
D013375 Substance Withdrawal Syndrome C00001179
D013921 Thrombocytopenia C00001179
D001749 Urinary Bladder Neoplasms C00001179
D012128 Respiratory Distress Syndrome, Adult C00000970
D007939 Leukemia L1210 C00003776
D014605 Uveitis C00003776