| class name | count |
|---|---|
| Liliopsida | 3 |
| eudicotyledons | 2 |
| asterids | 1 |
| rosids | 1 |
| class name | count |
|---|---|
| Cyperaceae | 2 |
| Rutaceae | 1 |
| Solanaceae | 1 |
| Montiaceae | 1 |
| Cactaceae | 1 |
| Poaceae | 1 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00001425
|
Octopamine
|
CHEMBL53929
CHEMBL1160703 |
D009655
|
16 / 8 / 6 | 7 / 0 |
|
|
C00034140
|
p-Hydroxymandelonitrile
|
C014601
|
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001425 | 1 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00001425 | 1 / 1 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00001425 | 2 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00001425 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00001425 | 3 / 2 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001425 | 0 / 1 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00001425 | 0 / 0 |
| P46098 | 5-hydroxytryptamine receptor 3A | NS | C00001425 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001425 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00001425 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001425 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001425 | 0 / 1 |
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00001425 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00001425 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001425 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001425 | 0 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 153 | ADRB1, ADRB1R, B1AR, BETA1AR, RHR | adrenoceptor beta 1 |
C00001425
|
| 154 | ADRB2, ADRB2R, ADRBR, B2AR, BAR, BETA2AR | adrenoceptor beta 2, surface |
C00001425
|
| 155 | ADRB3, BETA3AR | adrenoceptor beta 3 |
C00001425
|
| 6530 | SLC6A2, NAT1, NET, NET1, SLC6A5 | solute carrier family 6 (neurotransmitter transporter), member 2 |
C00001425
|
| 6531 | SLC6A3, DAT, DAT1, PKDYS | solute carrier family 6 (neurotransmitter transporter), member 3 |
C00001425
|
| 6532 | SLC6A4, 5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT | solute carrier family 6 (neurotransmitter transporter), member 4 |
C00001425
|
| 134864 | TAAR1, RP11-295F4.9, TA1, TAR1, TRAR1 | trace amine associated receptor 1 |
C00001425
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|