KCF-S cluster No. 750 (12 metabolites)

Corresponding Phytochemical cluster No. 25

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (12)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	35
asterids	6
eudicotyledons	4

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Cumulative family count

class name	count
Rutaceae	31
Apiaceae	6
Plumbaginaceae	4
Moraceae	4

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Coumarins	3

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metabolites link (3)

br08003 Category	KEGG ID	KNApSAcK ID
Coumarins	C09312	C00000300
Coumarins	C09273	C00002481
Coumarins	C09317	C00002505

Metabolite list (12)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00000300	Seselin / Amyrolin / Seseline	CHEMBL71358		2 / 0 / 0
C00002481	Luvangetin	CHEMBL254379
C00002505	Xanthyletin	CHEMBL303846	C020814	29 / 43 / 58
C00019778	Alloxanthoxyletol	CHEMBL480850
C00019928	5-Hydroxyseselin	CHEMBL448575
C00020024	Seselinol
C00032520	Xanthoxyletin	CHEMBL501358		14 / 5 / 7
C00036084	Cedrecoumarin A	CHEMBL491519		2 / 1 / 1
C00036600	5-Methoxyseselin	CHEMBL479894
C00037065	Dorstegin
C00037561	Norbraylin
C00044110	Braylin	CHEMBL529210

Human Protein / Gene in interactions

33 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00002505 C00032520	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002505 C00032520	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002505 C00032520	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00002505 C00032520	0 / 0
P43166	Carbonic anhydrase 7	Lyase	C00002505 C00032520	0 / 0
P04406	Glyceraldehyde-3-phosphate dehydrogenase	Enzyme	C00000300 C00002505	0 / 0
Q8N1Q1	Carbonic anhydrase 13	Lyase	C00002505 C00032520	0 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00002505 C00032520	0 / 1
P00918	Carbonic anhydrase 2	Lyase	C00002505 C00032520	1 / 2
P56817	Beta-secretase 1	A1A	C00000300 C00002505	0 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00002505 C00032520	2 / 2
O43570	Carbonic anhydrase 12	Lyase	C00002505 C00032520	1 / 2
P83916	Chromobox protein homolog 1	Unclassified protein	C00002505 C00032520	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00002505 C00032520	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00002505	7 / 37
P38398	Breast cancer type 1 susceptibility protein	Enzyme	C00002505	4 / 2
Q92731	Estrogen receptor beta	NR3A2	C00036084	0 / 1
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00002505	7 / 3
P51151	Ras-related protein Rab-9A	Unclassified protein	C00002505	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00002505	0 / 0
P37840	Alpha-synuclein	Unclassified protein	C00002505	4 / 2
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00002505	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002505	2 / 2
O15118	Niemann-Pick C1 protein	Unclassified protein	C00002505	1 / 1
P06746	DNA polymerase beta	Enzyme	C00002505	0 / 0
P03372	Estrogen receptor	NR3A1	C00036084	1 / 1
P22303	Acetylcholinesterase	Hydrolase	C00002505	1 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00002505	4 / 3
Q99700	Ataxin-2	Unclassified protein	C00002505	1 / 1
Q16637	Survival motor neuron protein	Unclassified protein	C00002505	4 / 1
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00032520	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00002505	1 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00032520	1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions