KCF-S cluster No. 3673 (3 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (3)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	10
Liliopsida	4
asterids	1

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Cumulative family count

class name	count
Rutaceae	9
Araceae	4
Oleaceae	1
Brassicaceae	1

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (3)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00001418	Indole	CHEMBL15844	C030374	13 / 5 / 6	6 / 0
C00026388	4-Hydroxyquinolin-2(1H)-one	CHEMBL223449		5 / 7 / 3
C00044432	2-Quinolone	CHEMBL186422	C107724	19 / 7 / 9	1 / 0

Human Protein / Gene in interactions

33 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P00918	Carbonic anhydrase 2	Lyase	C00001418 C00044432	1 / 2
P22748	Carbonic anhydrase 4	Lyase	C00001418 C00044432	1 / 1
P00915	Carbonic anhydrase 1	Lyase	C00001418 C00044432	0 / 0
P23280	Carbonic anhydrase 6	Lyase	C00001418 C00044432	0 / 0
P03956	Interstitial collagenase	M10A	C00044432	0 / 1
P14780	Matrix metalloproteinase-9	M10A	C00044432	2 / 2
Q8N1Q1	Carbonic anhydrase 13	Lyase	C00044432	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00044432	0 / 0
Q00535	Cyclin-dependent kinase 5	Cdk5	C00001418	0 / 0
Q15078	Cyclin-dependent kinase 5 activator 1	REG serine/threonine protein kinase family	C00001418	0 / 0
P43166	Carbonic anhydrase 7	Lyase	C00044432	0 / 0
Q9ULX7	Carbonic anhydrase 14	Lyase	C00044432	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00026388	0 / 0
O43570	Carbonic anhydrase 12	Lyase	C00044432	1 / 2
O75496	Geminin	Unclassified protein	C00026388	0 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00044432	0 / 0
P22894	Neutrophil collagenase	M10A	C00044432	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00026388	7 / 3
P55263	Adenosine kinase	Enzyme	C00001418	1 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00044432	0 / 1
P08253	72 kDa type IV collagenase	M10A	C00044432	1 / 3
P07451	Carbonic anhydrase 3	Lyase	C00044432	0 / 0
P08254	Stromelysin-1	M10A	C00044432	1 / 0
P23141	Liver carboxylesterase 1	Enzyme	C00001418	0 / 0
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00044432	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00044432	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00026388	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00026388	0 / 0
P05107	Integrin beta-2	Membrane receptor	C00001418	1 / 1
P05362	Intercellular adhesion molecule 1	Adhesion	C00001418	1 / 2
P20701	Integrin alpha-L	Membrane receptor	C00001418	0 / 0
P49840	Glycogen synthase kinase-3 alpha	Gsk	C00001418	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00001418	0 / 0

7 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00001418
405	ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2	aryl hydrocarbon receptor nuclear translocator	C00001418
4157	MC1R, CMM5, MSH-R, SHEP2	melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)	C00001418
4159	MC3R, BMIQ9, MC3, MC3-R, OB20, OQTL	melanocortin 3 receptor	C00001418
4160	MC4R	melanocortin 4 receptor	C00001418
4161	MC5R, MC2	melanocortin 5 receptor	C00001418
5444	PON1, ESA, MVCD5, PON	paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81)	C00044432

Related Diseases

Diseases related to proteins in ChEMBL interactions