Dipteryx odorata
Species
KNApSAcK Entry
| Organism name | Dipteryx odorata |
|---|---|
| Genus | Dipteryx |
| Family | Fabaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Dipteryx odorata |
|---|---|
| Linked NCBI taxonomy ID | 53873 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Fabaceae |
|---|---|
| ID | 3803 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Natural Activity
List (95)
| Species | Activity |
|---|---|
| Dipteryx odorata (Aubl.) Willd. | Analgesic |
| Dipteryx odorata (Aubl.) Willd. | Anesthetic |
| Dipteryx odorata (Aubl.) Willd. | Antiaggregant |
| Dipteryx odorata (Aubl.) Willd. | Antiaggregant |
| Dipteryx odorata (Aubl.) Willd. | Antiandrogenic |
| Dipteryx odorata (Aubl.) Willd. | Antiasthmatic |
| Dipteryx odorata (Aubl.) Willd. | Antidiuretic |
| Dipteryx odorata (Aubl.) Willd. | Antiedemic |
| Dipteryx odorata (Aubl.) Willd. | Antiescherichia |
| Dipteryx odorata (Aubl.) Willd. | Antiinflammatory |
| Dipteryx odorata (Aubl.) Willd. | Antimitotic |
| Dipteryx odorata (Aubl.) Willd. | Antimononucleotic |
| Dipteryx odorata (Aubl.) Willd. | Antimutagenic |
| Dipteryx odorata (Aubl.) Willd. | Antimycoplasmotic |
| Dipteryx odorata (Aubl.) Willd. | Antioxidant |
| Dipteryx odorata (Aubl.) Willd. | Antioxidant |
| Dipteryx odorata (Aubl.) Willd. | Antipsittacotic |
| Dipteryx odorata (Aubl.) Willd. | Antipsoriac |
| Dipteryx odorata (Aubl.) Willd. | Antipyretic |
| Dipteryx odorata (Aubl.) Willd. | Antiseptic |
| Dipteryx odorata (Aubl.) Willd. | Antiseptic |
| Dipteryx odorata (Aubl.) Willd. | Antispasmodic |
| Dipteryx odorata (Aubl.) Willd. | Antispasmodic |
| Dipteryx odorata (Aubl.) Willd. | Antitoxoplasmotic |
| Dipteryx odorata (Aubl.) Willd. | Antitussive |
| Dipteryx odorata (Aubl.) Willd. | Antitussive |
| Dipteryx odorata (Aubl.) Willd. | Aphrodisiac |
| Dipteryx odorata (Aubl.) Willd. | Aphrodisiac |
| Dipteryx odorata (Aubl.) Willd. | Bacteria |
| Dipteryx odorata (Aubl.) Willd. | Brucellosis |
| Dipteryx odorata (Aubl.) Willd. | Bruise |
| Dipteryx odorata (Aubl.) Willd. | Cachexia |
| Dipteryx odorata (Aubl.) Willd. | Cancer, kidney |
| Dipteryx odorata (Aubl.) Willd. | Cancer, prostate |
| Dipteryx odorata (Aubl.) Willd. | Canker |
| Dipteryx odorata (Aubl.) Willd. | Cardiopathy |
| Dipteryx odorata (Aubl.) Willd. | Cardiotonic |
| Dipteryx odorata (Aubl.) Willd. | Cardiotonic |
| Dipteryx odorata (Aubl.) Willd. | Cardiotoxic |
| Dipteryx odorata (Aubl.) Willd. | Cardiotoxic |
| Dipteryx odorata (Aubl.) Willd. | Chemopreventive |
| Dipteryx odorata (Aubl.) Willd. | Cough |
| Dipteryx odorata (Aubl.) Willd. | Cramp |
| Dipteryx odorata (Aubl.) Willd. | Diabetes |
| Dipteryx odorata (Aubl.) Willd. | Diaphoretic |
| Dipteryx odorata (Aubl.) Willd. | Diaphoretic |
| Dipteryx odorata (Aubl.) Willd. | Dyspepsia |
| Dipteryx odorata (Aubl.) Willd. | Earache |
| Dipteryx odorata (Aubl.) Willd. | Edema |
| Dipteryx odorata (Aubl.) Willd. | Elephantiasis |
| Dipteryx odorata (Aubl.) Willd. | Emmenagogue |
| Dipteryx odorata (Aubl.) Willd. | Escherichia |
| Dipteryx odorata (Aubl.) Willd. | Febrifuge |
| Dipteryx odorata (Aubl.) Willd. | Fever |
| Dipteryx odorata (Aubl.) Willd. | Fumitory |
| Dipteryx odorata (Aubl.) Willd. | Fumitory |
| Dipteryx odorata (Aubl.) Willd. | Fungus |
| Dipteryx odorata (Aubl.) Willd. | Hepatotoxic |
| Dipteryx odorata (Aubl.) Willd. | Hepatotoxic |
| Dipteryx odorata (Aubl.) Willd. | Hyperglycemia |
| Dipteryx odorata (Aubl.) Willd. | Infection |
| Dipteryx odorata (Aubl.) Willd. | Inflammation |
| Dipteryx odorata (Aubl.) Willd. | Insomnia |
| Dipteryx odorata (Aubl.) Willd. | Lymphedema |
| Dipteryx odorata (Aubl.) Willd. | Lymphoma |
| Dipteryx odorata (Aubl.) Willd. | Melanoma |
| Dipteryx odorata (Aubl.) Willd. | Metastasis |
| Dipteryx odorata (Aubl.) Willd. | Mononucleosis |
| Dipteryx odorata (Aubl.) Willd. | Mycoplasm |
| Dipteryx odorata (Aubl.) Willd. | Mycosis |
| Dipteryx odorata (Aubl.) Willd. | Narcotic |
| Dipteryx odorata (Aubl.) Willd. | Narcotic |
| Dipteryx odorata (Aubl.) Willd. | Nausea |
| Dipteryx odorata (Aubl.) Willd. | Nephrosis |
| Dipteryx odorata (Aubl.) Willd. | Pain |
| Dipteryx odorata (Aubl.) Willd. | Pertussis |
| Dipteryx odorata (Aubl.) Willd. | Propecic |
| Dipteryx odorata (Aubl.) Willd. | Prostatosis |
| Dipteryx odorata (Aubl.) Willd. | Psittacosis |
| Dipteryx odorata (Aubl.) Willd. | Rheumatism |
| Dipteryx odorata (Aubl.) Willd. | Schistosomiasis |
| Dipteryx odorata (Aubl.) Willd. | Snakebite |
| Dipteryx odorata (Aubl.) Willd. | Sore |
| Dipteryx odorata (Aubl.) Willd. | Sore Throat |
| Dipteryx odorata (Aubl.) Willd. | Spasm |
| Dipteryx odorata (Aubl.) Willd. | Stimulant |
| Dipteryx odorata (Aubl.) Willd. | Stimulant |
| Dipteryx odorata (Aubl.) Willd. | Stomachic |
| Dipteryx odorata (Aubl.) Willd. | Stomachic |
| Dipteryx odorata (Aubl.) Willd. | Stomatosis |
| Dipteryx odorata (Aubl.) Willd. | Tonic |
| Dipteryx odorata (Aubl.) Willd. | Tonic |
| Dipteryx odorata (Aubl.) Willd. | Toxoplasmosis |
| Dipteryx odorata (Aubl.) Willd. | Tuberculosis |
| Dipteryx odorata (Aubl.) Willd. | Ulcer |
Metabolite list (20)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00009407
|
Odoratin
|
CHEMBL469824
|
No. 3 | No. 15 |
|
|||
|
C00009393
|
Retusin(Dalbergia)
/ 7,8-Dihydroxy-4'-methoxyisoflavone |
CHEMBL1290231
|
No. 3 | No. 15 |
|
|||
|
C00009400
|
8-O-Methylretusin
|
CHEMBL477720
|
No. 3 | No. 15 |
|
|||
|
C00019027
|
7,8,3'-Trihydroxy-6,4'-dimethoxyisoflavone
|
No. 3 | No. 15 |
|
||||
|
C00009408
|
3'-Hydroxy-8-O-methylretusin
|
CHEMBL465572
|
No. 3 | No. 15 |
|
|||
|
C00009409
|
Dipteryxin
|
No. 3 | No. 15 |
|
||||
|
C00000945
|
Butin
/ 7,3',4'-Trihydroxyflavanone |
CHEMBL451168
|
C051437
|
No. 25 | No. 14 |
|
||
|
C00000960
|
Eriodictyol
|
CHEMBL8996
CHEMBL307893 CHEMBL1975989 |
C007619
|
32 / 29 / 55 | 5 / 0 | No. 25 | No. 14 |
|
|
C00009476
|
Dipteryxine
/ Isoplatycarpanetin / 7-Hydroxy-5,6-dimethoxy-3',4'-methylenedioxyisoflavone |
No. 27 | No. 15 |
|
||||
|
C00009482
|
Odorantin
/ Odoratine / Diptodoratidin / 5,6,7-Trimethoxy-3',4'-methylenedioxyisoflavone |
No. 27 | No. 15 |
|
||||
|
C00002507
|
Castanin
/ Afromosin / Afrormosin / 7-Hydroxy-6,4'-dimethoxyisoflavone |
CHEMBL464404
|
C080240
|
7 / 14 / 39 | 1 / 0 | No. 35 | No. 15 |
|
|
C00006925
|
Isoliquiritigenin
|
CHEMBL129795
CHEMBL1395334 |
C040920
|
59 / 83 / 90 | 12 / 3 | No. 92 | No. 13 |
|
|
C00044465
|
5-Methoxyxanthocercin A
|
CHEMBL466784
|
No. 338 |
|
||||
|
C00044469
|
6,4'-Dihydroxy-3'-methoxyaurone
|
CHEMBL446827
|
28 / 32 / 55 | No. 450 | No. 13 |
|
||
|
C00008026
|
Sulfuretin
/ Sulphuretin / 6,3',4'-Trihydroxyaurone |
CHEMBL490355
CHEMBL513487 |
C054989
|
42 / 37 / 34 | No. 450 | No. 13 |
|
|
|
C00000603
|
(-)-Lariciresinol
|
CHEMBL518421
|
C060282
|
2 / 1 / 1 | No. 700 | No. 21 |
|
|
|
C00002729
|
o-Coumaric acid
|
CHEMBL52564
|
C085894
|
17 / 6 / 17 | No. 904 | No. 6 |
|
|
|
C00002460
|
Coumarin
|
CHEMBL6466
|
C030123
|
122 / 60 / 55 | 11 / 7 | No. 1030 | No. 25 |
|
|
C00032062
|
Neocaesalpin H
/ Dipteryxic acid |
CHEMBL468658
|
No. 3110 |
|
||||
|
C00044485
|
7-Hydroxychromone
|
CHEMBL58827
|
No. 3998 | No. 15 |
|
Human Protein / Gene in interactions
203 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000960 C00002460 C00006925 C00008026 C00044469 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00000960 C00002507 C00006925 C00044469 | 7 / 37 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00002507 C00006925 C00008026 C00044469 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00000960 C00002507 C00006925 C00044469 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000603 C00000960 C00002460 C00006925 | 0 / 1 |
| P39748 | Flap endonuclease 1 | Enzyme | C00000960 C00006925 C00008026 C00044469 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000960 C00006925 C00008026 C00044469 | 4 / 3 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000960 C00008026 C00044469 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000603 C00002460 C00006925 | 1 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00000960 C00008026 C00044469 | 2 / 1 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00002507 C00008026 C00044469 | 4 / 2 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00006925 C00008026 C00044469 | 0 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00002460 C00008026 C00044469 | 1 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00006925 C00008026 C00044469 | 1 / 2 |
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00000960 C00006925 C00008026 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000960 C00002460 C00006925 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000960 C00002460 C00006925 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00000960 C00008026 C00044469 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00006925 C00008026 C00044469 | 2 / 5 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00000960 C00006925 C00008026 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00000960 C00008026 C00044469 | 1 / 1 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00000960 C00006925 C00008026 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00006925 C00008026 C00044469 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00006925 C00008026 | 2 / 3 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00002460 C00002729 | 1 / 1 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00002460 C00002729 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00002460 C00006925 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00002460 C00008026 | 0 / 1 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00002460 C00006925 | 2 / 2 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00002460 C00002729 | 0 / 0 |
| Q8N1Q1 | Carbonic anhydrase 13 | Lyase | C00002460 C00002729 | 0 / 0 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00002460 C00002729 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00002460 C00006925 | 11 / 10 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00002460 C00008026 | 1 / 4 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00000960 C00008026 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00002460 C00008026 | 3 / 1 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00002460 C00002729 | 1 / 2 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00002460 C00006925 | 1 / 1 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00000960 C00006925 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00002729 C00006925 | 0 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00000960 C00002460 | 1 / 0 |
| Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00008026 C00044469 | 0 / 0 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00008026 C00044469 | 1 / 1 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000960 C00006925 | 2 / 2 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000960 C00006925 | 3 / 3 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00002460 C00002729 | 0 / 1 |
| P06746 | DNA polymerase beta | Enzyme | C00000960 C00044469 | 0 / 0 |
| P10696 | Alkaline phosphatase, placental-like | Enzyme | C00000960 C00008026 | 0 / 1 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00006925 C00008026 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00002460 C00006925 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00002460 C00006925 | 0 / 1 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00002507 C00006925 | 1 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00006925 C00044469 | 0 / 0 |
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00008026 C00044469 | 0 / 0 |
| P11308 | Transcriptional regulator ERG | Unclassified protein | C00008026 C00044469 | 1 / 2 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00002460 C00006925 | 2 / 2 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00002460 C00006925 | 1 / 8 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00002460 C00002729 | 0 / 0 |
| P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | Enzyme | C00000960 C00008026 | 3 / 1 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00002460 C00006925 | 0 / 0 |
| P09923 | Intestinal-type alkaline phosphatase | Enzyme | C00000960 C00008026 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00000960 C00008026 | 1 / 1 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00008026 C00044469 | 7 / 3 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00002460 C00006925 | 0 / 3 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00002460 C00002729 | 0 / 0 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00002460 C00002729 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00002460 C00006925 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00002460 C00006925 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00002507 C00044469 | 0 / 0 |
| P14618 | Pyruvate kinase PKM | Enzyme | C00000960 C00006925 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00006925 C00008026 | 2 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00008026 C00044469 | 0 / 0 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00002460 C00002729 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00006925 C00044469 | 1 / 1 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00002460 C00002729 | 1 / 2 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00002507 | 2 / 2 |
| P36888 | Receptor-type tyrosine-protein kinase FLT3 | Pdgfr | C00000960 | 1 / 1 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00002460 | 0 / 0 |
| Q8TDS4 | Hydroxycarboxylic acid receptor 2 | Hydroxycarboxylic acid receptor | C00002729 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00000960 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00002460 | 1 / 0 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00002460 | 0 / 0 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00000960 | 0 / 0 |
| P17538 | Chymotrypsinogen B | S1A | C00002460 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00002460 | 1 / 1 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00002460 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00002460 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00002460 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00002460 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00002460 | 1 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00002460 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00002460 | 0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00002460 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00002460 | 0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00002460 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00002460 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00002460 | 1 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00002460 | 0 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00002460 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00002460 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00002460 | 1 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00002460 | 0 / 0 |
| P03956 | Interstitial collagenase | M10A | C00002460 | 0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00002460 | 0 / 0 |
| P47901 | Vasopressin V1b receptor | Vasopressin and oxytocin receptor | C00008026 | 0 / 0 |
| Q04206 | Transcription factor p65 | Transcription Factor | C00006925 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00002460 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00002460 | 0 / 0 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00002460 | 2 / 0 |
| Q9HBX9 | Relaxin receptor 1 | Relaxin receptor | C00008026 | 0 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00006925 | 1 / 2 |
| P24385 | G1/S-specific cyclin-D1 | Other cytosolic protein | C00002729 | 1 / 8 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00008026 | 0 / 0 |
| Q9NPD5 | Solute carrier organic anion transporter family member 1B3 | Electrochemical transporter | C00002460 | 1 / 0 |
| P11802 | Cyclin-dependent kinase 4 | CMGC serine/threonine protein kinase family | C00002729 | 1 / 3 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00002460 | 0 / 0 |
| Q99816 | Tumor susceptibility gene 101 protein | Unclassified protein | C00044469 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00002460 | 0 / 1 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00002460 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00002460 | 0 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00002460 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00002460 | 2 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00006925 | 5 / 3 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00002460 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00002460 | 1 / 0 |
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00000960 | 4 / 4 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00002460 | 0 / 0 |
| P12931 | Proto-oncogene tyrosine-protein kinase Src | Src | C00006925 | 0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00002460 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00002460 | 3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00002460 | 0 / 0 |
| P35968 | Vascular endothelial growth factor receptor 2 | Vegfr | C00006925 | 1 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00002460 | 0 / 0 |
| P08581 | Hepatocyte growth factor receptor | TK tyrosine-protein kinase MET subfamily | C00006925 | 2 / 3 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00002460 | 1 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00002460 | 0 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00002460 | 0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00002460 | 2 / 1 |
| P56817 | Beta-secretase 1 | A1A | C00002460 | 0 / 0 |
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00000960 | 0 / 0 |
| P02768 | Serum albumin | Secreted protein | C00002460 | 0 / 0 |
| P08253 | 72 kDa type IV collagenase | M10A | C00008026 | 1 / 3 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00002460 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00002460 | 0 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00002460 | 0 / 0 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00006925 | 5 / 2 |
| Q8WXD0 | Relaxin receptor 2 | Relaxin receptor | C00008026 | 1 / 1 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00002460 | 1 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00002460 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00002460 | 1 / 1 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00002460 | 1 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00002460 | 0 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00002460 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00002460 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00002460 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00002460 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00002460 | 0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00002460 | 0 / 0 |
| P11362 | Fibroblast growth factor receptor 1 | Fgfr | C00006925 | 4 / 5 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00002460 | 0 / 0 |
| Q00796 | Sorbitol dehydrogenase | Enzyme | C00002460 | 0 / 0 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00002460 | 0 / 0 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00002460 | 1 / 1 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00002460 | 0 / 1 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00002729 | 1 / 1 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00002460 | 0 / 0 |
| P37840 | Alpha-synuclein | Unclassified protein | C00006925 | 4 / 2 |
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00006925 | 1 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00000960 | 0 / 0 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00044469 | 0 / 0 |
| P04406 | Glyceraldehyde-3-phosphate dehydrogenase | Enzyme | C00002460 | 0 / 0 |
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00006925 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00002460 | 0 / 0 |
| P07477 | Trypsin-1 | S1A | C00002460 | 1 / 1 |
| P10275 | Androgen receptor | NR3C4 | C00002460 | 3 / 4 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00002460 | 1 / 1 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00002460 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00002460 | 0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00002460 | 0 / 0 |
| P10721 | Mast/stem cell growth factor receptor Kit | Pdgfr | C00006925 | 4 / 3 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00002460 | 1 / 1 |
| P05412 | Transcription factor AP-1 | Transcription Factor | C00006925 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00002460 | 0 / 0 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00002460 | 0 / 1 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00002460 | 0 / 0 |
| P29466 | Caspase-1 | C14 | C00002460 | 0 / 0 |
| P04062 | Glucosylceramidase | Enzyme | C00006925 | 6 / 4 |
| O14980 | Exportin-1 | Unclassified protein | C00002460 | 0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00002460 | 0 / 0 |
| P21802 | Fibroblast growth factor receptor 2 | TK tyrosine-protein kinase TLK subfamily | C00006925 | 9 / 3 |
| P40225 | Thrombopoietin | Unclassified protein | C00006925 | 1 / 1 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00002460 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00002460 | 1 / 1 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00002460 | 0 / 0 |
| P08246 | Neutrophil elastase | S1A | C00002460 | 2 / 1 |
| O00487 | 26S proteasome non-ATPase regulatory subunit 14 | Enzyme | C00008026 | 0 / 0 |
| O94956 | Solute carrier organic anion transporter family member 2B1 | Unclassified protein | C00002460 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00008026 | 0 / 0 |
| Q9Y6L6 | Solute carrier organic anion transporter family member 1B1 | Electrochemical transporter | C00002460 | 1 / 0 |
| Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Other cytosolic protein | C00008026 | 0 / 0 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00006925 | 0 / 0 |
| P42345 | Serine/threonine-protein kinase mTOR | Enzyme | C00006925 | 0 / 0 |
| P51531 | Probable global transcription activator SNF2L2 | Unclassified protein | C00006925 | 1 / 0 |
28 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00000960
C00002507
|
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00002460
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00000960
|
| 4780 | NFE2L2, NRF2 | nuclear factor, erythroid 2-like 2 |
C00000960
|
| 29110 | TBK1, NAK, T2K | TANK-binding kinase 1 (EC:2.7.11.1) |
C00000960
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00002460
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00002460
|
| 1546 |
C00002460
|
||
| 1553 | CYP2A13, CPAD, CYP2A, CYPIIA13 | cytochrome P450, family 2, subfamily A, polypeptide 13 (EC:1.14.14.1) |
C00002460
|
| 1548 | CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB | cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) |
C00002460
|
| 1559 | CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 | cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00002460
|
| 2158 | F9, FIX, HEMB, P19, PTC, THPH8 | coagulation factor IX (EC:3.4.21.22) |
C00002460
|
| 3292 | HSD17B1, EDH17B2, EDHB17, HSD17, SDR28C1 | hydroxysteroid (17-beta) dehydrogenase 1 (EC:1.1.1.62) |
C00002460
|
| 4256 | MGP, MGLAP, NTI | matrix Gla protein |
C00002460
|
| 2950 | GSTP1, DFN7, FAEES3, GST3, GSTP, PI | glutathione S-transferase pi 1 (EC:2.5.1.18) |
C00000960
|
| 79001 | VKORC1, EDTP308, IMAGE3455200, MST134, MST576, VKCFD2, VKOR | vitamin K epoxide reductase complex, subunit 1 (EC:1.1.4.1) |
C00002460
|
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 |
C00006925
|
| 329 | BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1 | baculoviral IAP repeat containing 2 |
C00006925
|
| 330 | BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 | baculoviral IAP repeat containing 3 |
C00006925
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00006925
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00006925
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00006925
|
| 6513 | SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED | solute carrier family 2 (facilitated glucose transporter), member 1 |
C00006925
|
| 54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) |
C00006925
|
| 54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) |
C00006925
|
| 54577 | UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G | UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) |
C00006925
|
| 54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) |
C00006925
|
| 54600 | UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I | UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) |
C00006925
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (152)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #207410 | Antley-bixler syndrome without genital anomalies or disordered steroidogenesis; abs2 |
P21802
|
| #101200 | Apert syndrome |
P21802
|
| #608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #123790 | Beare-stevenson cutis gyrata syndrome; bstvs |
P21802
|
| #614592 | Bent bone dysplasia syndrome; bbds |
P21802
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| %606641 | Body mass index; bmi |
P37231
|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #300615 | Brunner syndrome |
P21397
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #114500 | Colorectal cancer; crc |
P84022
Q14191 |
| #123500 | Crouzon syndrome |
P21802
|
| #219050 | Cryptorchidism, unilateral or bilateral |
Q8WXD0
|
| #162800 | Cyclic neutropenia |
P08246
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #133239 | Esophageal cancer |
P04637
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #612219 | Ewing sarcoma; es |
P11308
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #606764 | Gastrointestinal stromal tumor; gist |
P10721
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
| #231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
| #137760 | Glaucoma, primary open angle; poag |
Q16678
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P04626 P37231 |
| #232300 | Glycogen storage disease ii |
P10253
|
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #602089 | Hemangioma, capillary infantile |
P35968
|
| #114550 | Hepatocellular carcinoma |
P08581
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #237450 | Hyperbilirubinemia, rotor type; hblrr |
Q9NPD5
Q9Y6L6 |
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #147950 | Hypogonadotropic hypogonadism 2 with or without anosmia; hh2 |
P11362
|
| #146300 | Hypophosphatasia, adult |
P05186
|
| #241510 | Hypophosphatasia, childhood |
P05186
|
| #241500 | Hypophosphatasia, infantile |
P05186
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #123150 | Jackson-weiss syndrome; jws |
P21802
|
| #149730 | Lacrimoauriculodentodigital syndrome; ladd |
P21802
|
| #601626 | Leukemia, acute myeloid; aml |
P10721
P36888 |
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 P04637 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #609048 | Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 |
P11802
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #254500 | Myeloma, multiple |
P24385
|
| #159900 | Myoclonic dystonia |
P14416
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #601358 | Nicolaides-baraitser syndrome; ncbrs |
P51531
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #601665 | Obesity |
P32245
P37231 |
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #166250 | Osteoglophonic dysplasia; ogd |
P11362
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
P38398 |
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #167800 | Pancreatitis, hereditary; pctt |
P07477
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
P37840 |
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #604229 | Peters anomaly |
Q16678
|
| #101600 | Pfeiffer syndrome |
P11362
P21802 |
| #172700 | Pick disease of brain |
P10636
|
| #172800 | Piebald trait; pbt |
P10721
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #605074 | Renal cell carcinoma, papillary, 1; rccp1 |
P08581
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #609579 | Scaphocephaly, maxillary retrusion, and mental retardation |
P21802
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #273300 | Testicular germ cell tumor; tgct |
P10721
|
| #187950 | Thrombocythemia 1; thcyt1 |
P40225
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #190440 | Trigonocephaly 1; trigno1 |
P11362
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #278300 | Xanthinuria, type i |
P47989
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (126)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
P04637 (marker) P08581 (related) Q16790 (marker) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) P24385 (related) P24385 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P24385 (related) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) P04637 (related) P08581 (related) P21802 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) P04637 (related) P08253 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) P11802 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) P11802 (related) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) P24385 (related) P24385 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) P04637 (related) Q92731 (marker) |
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
P37840 (related) |
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00019 | Pancreatic cancer |
P04626
(related)
P04637 (related) P04637 (marker) |
| H00027 | Ovarian cancer |
P04626
(related)
P04637 (related) P38398 (related) |
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) P04637 (related) P24385 (related) P38398 (related) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P04637 (related) P08581 (related) P35354 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
P24385 (related) |
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
P24385 (related) |
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P08253 (related) P14780 (related) P35354 (related) |
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
P37231 (related) |
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
P11802 (related) |
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
P24385 (marker) |
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00213 | Hypophosphatasia |
P05186
(related)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00933 | Hereditary pancreatitis |
P07477
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
P11308 (related) |
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
Q8WXD0 (related) |
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00023 | Testicular cancer |
P10696
(marker)
P10721 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
P10721
(related)
P10721 (marker) P36888 (related) Q01196 (related) Q01196 (marker) Q13951 (marker) |
| H00170 | Piebaldism |
P10721
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00035 | Ewing's sarcoma |
P11308
(related)
|
| H00255 | Hypogonadotropic hypogonadism |
P11362
(related)
|
| H00443 | Osteoglophonic dysplasia (OD) |
P11362
(related)
|
| H00458 | Craniosynostosis |
P11362
(related)
P21802 (related) |
| H00516 | Isolated orofacial clefts |
P11362
(related)
|
| H01207 | Trigonocephaly |
P11362
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H00642 | Lacrimo-auriculo-dento-digital syndrome (LADD) |
P21802
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00559 | von Hippel-Lindau syndrome |
P24385
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
Q99714 (related) |
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
Q14191 (related) |
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00612 | Primary open angle glaucoma |
Q16678
(related)
|
| H01075 | Peters anomaly |
Q16678
(related)
|
| H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
| H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
Diseases related to CTD interactions
10 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D003924 | Diabetes Mellitus, Type 2 |
C00002460
|
| D056486 | Drug-Induced Liver Injury |
C00002460
|
| D007674 | Kidney Diseases |
C00002460
|
| D009336 | Necrosis |
C00002460
|
| D012871 | Skin Diseases |
C00002460
|
| D013927 | Thrombosis |
C00002460
|
| D014689 | Venous Insufficiency |
C00002460
|
| D001927 | Brain Diseases |
C00006925
|
| D009120 | Muscle Cramp |
C00006925
|
| D009422 | Nervous System Diseases |
C00006925
|