KNApSAcK Entry

id C00006925
Name Isoliquiritigenin
CAS RN 961-29-5
Standard InChI InChI=1S/C15H12O4/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-9,16-17,19H/b8-3+
Standard InChI (Main Layer) InChI=1S/C15H12O4/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-9,16-17,19H


Phytochemical cluster No. 13
KCF-S cluster No. 92



By standard InChI CHEMBL129795
By standard InChI Main Layer CHEMBL129795 CHEMBL1395334


By LinkDB C08650


By CAS RN C040920



List (36)

KNApSAcK organism *ID *family *plant class *kingdom
Acacia rhodoxylon 3808 Fabaceae rosids Viridiplantae
Agapanthus africanus 51501 Amaryllidaceae Liliopsida Viridiplantae
Arabidopsis thaliana 3702 Brassicaceae rosids Viridiplantae
Bauhinia manca 3805 Fabaceae rosids Viridiplantae
Brosimum acutifolium 194252 Moraceae rosids Viridiplantae
Broussonetia papyrifera 172644 Moraceae rosids Viridiplantae
Clausena excavata 76959 Rutaceae rosids Viridiplantae
Crinum bulbispermum Milne 16055 Amaryllidaceae Liliopsida Viridiplantae
Dahlia variabilis 101596 Asteraceae asterids Viridiplantae
Dalbergia ecastaphyllum 450024 Fabaceae rosids Viridiplantae
Dalbergia odorifera 499988 Fabaceae rosids Viridiplantae
Dipteryx odorata 53873 Fabaceae rosids Viridiplantae
Dracaena draco 100532 Asparagaceae Liliopsida Viridiplantae
Flemingia chappar 520842 Fabaceae rosids Viridiplantae
Glycine max 3847 Fabaceae rosids Viridiplantae
Glycyrrhiza glabra 49827 Fabaceae rosids Viridiplantae
Glycyrrhiza glara 46347 Fabaceae rosids Viridiplantae
Glycyrrhiza inflata 74614 Fabaceae rosids Viridiplantae
Glycyrrhiza pallidiflora 74859 Fabaceae rosids Viridiplantae
Lespedeza bicolor 556514 Fabaceae rosids Viridiplantae
Medicago spp. 3877 Fabaceae rosids Viridiplantae
Medicago truncatula 3880 Fabaceae rosids Viridiplantae
Millettia usaramensis subsp. usaramensis 53625 Fabaceae rosids Viridiplantae
Onobrychis viciifolia Scop. 3882 Fabaceae rosids Viridiplantae
Oxytropis pseudoglandulosa 20802 Fabaceae rosids Viridiplantae
Pancratium maritimum L. 644807 Amaryllidaceae Liliopsida Viridiplantae
Psorothamnus arborescens 248527 Fabaceae rosids Viridiplantae
Pterocarpus marsupium 1071187 Fabaceae rosids Viridiplantae
Pterocarpus santalinus 1071199 Fabaceae rosids Viridiplantae
Robinia pseudoacacia 35938 Fabaceae rosids Viridiplantae
Sophora gypsophila 3896 Fabaceae rosids Viridiplantae
Tephrosia toxicaria 3803 Fabaceae rosids Viridiplantae
Tithonia brachypappa 105386 Asteraceae asterids Viridiplantae
Trifolium subterraneum 3900 Fabaceae rosids Viridiplantae
Viguiera spp. 73317 Asteraceae asterids Viridiplantae
Zollernia paraensis 1231576 Fabaceae rosids Viridiplantae

Human Protein / Gene in interaction

59 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL1395334 CHEMBL1614110 (1) CHEMBL1741321 (1)
1 / 0
P42345 Serine/threonine-protein kinase mTOR Enzyme CHEMBL129795 CHEMBL1613805 (1)
0 / 0
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr CHEMBL129795 CHEMBL972808 (1) CHEMBL1041717 (1)
0 / 0
P04637 Cellular tumor antigen p53 Transcription Factor CHEMBL129795 CHEMBL1395334 CHEMBL1613992 (1) CHEMBL1738132 (1)
7 / 44
Q99700 Ataxin-2 Unclassified protein CHEMBL129795 CHEMBL1794367 (1) CHEMBL2114784 (1)
1 / 1
P14618 Pyruvate kinase PKM Enzyme CHEMBL1395334 CHEMBL1614177 (1) CHEMBL1614265 (1)
0 / 0
P21728 D(1A) dopamine receptor Dopamine receptor CHEMBL129795 CHEMBL1737859 (1)
0 / 0
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) CHEMBL129795 CHEMBL1794573 (1)
2 / 2
P21802 Fibroblast growth factor receptor 2 TK tyrosine-protein kinase TLK subfamily CHEMBL129795 CHEMBL986526 (1)
9 / 3
P04062 Glucosylceramidase Enzyme CHEMBL129795 CHEMBL1614232 (1) CHEMBL1614243 (1)
CHEMBL1614515 (1) CHEMBL1613812 (1)
CHEMBL1614044 (1) CHEMBL1613818 (4)
6 / 4
P14780 Matrix metalloproteinase-9 M10A CHEMBL129795 CHEMBL1913491 (1) CHEMBL1913492 (1)
CHEMBL1913493 (1)
2 / 2
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL129795 CHEMBL1738600 (1)
0 / 0
P02545 Prelamin-A/C Unclassified protein CHEMBL129795 CHEMBL1614544 (2)
11 / 10
P37840 Alpha-synuclein Unclassified protein CHEMBL129795 CHEMBL2354282 (1)
4 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL129795 CHEMBL1395334 CHEMBL1614027 (2) CHEMBL1741325 (1)
0 / 1
P54132 Bloom syndrome protein Enzyme CHEMBL129795 CHEMBL1614522 (1) CHEMBL1614067 (1)
1 / 2
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily CHEMBL129795 CHEMBL986517 (1)
1 / 11
P11473 Vitamin D3 receptor NR1I1 CHEMBL129795 CHEMBL1794311 (3)
2 / 3
P39748 Flap endonuclease 1 Enzyme CHEMBL129795 CHEMBL1794486 (1)
0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein CHEMBL129795 CHEMBL1794584 (1)
2 / 0
O75496 Geminin Unclassified protein CHEMBL129795 CHEMBL1613941 (1) CHEMBL1738636 (1)
CHEMBL2114843 (1) CHEMBL2114780 (1)
0 / 0
P15121 Aldose reductase Enzyme CHEMBL129795 CHEMBL1942674 (1)
0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL129795 CHEMBL2114788 (1)
0 / 0
Q04206 Transcription factor p65 Transcription Factor CHEMBL129795 CHEMBL1913508 (1)
0 / 0
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL129795 CHEMBL1614257 (3) CHEMBL1614410 (1)
CHEMBL1614531 (1)
1 / 3
P83916 Chromobox protein homolog 1 Unclassified protein CHEMBL129795 CHEMBL1738610 (1)
0 / 0
P11021 78 kDa glucose-regulated protein Unclassified protein CHEMBL129795 CHEMBL1963893 (2)
0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme CHEMBL129795 CHEMBL1794467 (2)
0 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 CHEMBL129795 CHEMBL1059360 (1) CHEMBL1059361 (1)
5 / 3
P12931 Proto-oncogene tyrosine-protein kinase Src Src CHEMBL129795 CHEMBL986511 (1)
0 / 0
P35968 Vascular endothelial growth factor receptor 2 Vegfr CHEMBL129795 CHEMBL986515 (1)
1 / 0
P08581 Hepatocyte growth factor receptor TK tyrosine-protein kinase MET subfamily CHEMBL129795 CHEMBL986512 (1)
2 / 3
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL1395334 CHEMBL1613808 (1)
0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL1395334 CHEMBL1741322 (1)
0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme CHEMBL1395334 CHEMBL1614227 (1)
3 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme CHEMBL129795 CHEMBL1614038 (1)
2 / 2
Q01453 Peripheral myelin protein 22 Unclassified protein CHEMBL129795 CHEMBL1614171 (1)
5 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein CHEMBL129795 CHEMBL1738588 (1) CHEMBL1738675 (1)
CHEMBL1737868 (1) CHEMBL1738317 (1)
0 / 0
P11362 Fibroblast growth factor receptor 1 Fgfr CHEMBL129795 CHEMBL986513 (1)
4 / 5
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor CHEMBL1395334 CHEMBL1614274 (1) CHEMBL1613823 (1)
0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme CHEMBL1395334 CHEMBL1614240 (1)
0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL129795 CHEMBL1395334 CHEMBL1613777 (2) CHEMBL1741323 (1)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL129795 CHEMBL1395334 CHEMBL1614108 (3) CHEMBL1613886 (3)
CHEMBL1741324 (1)
0 / 1
Q9UNA4 DNA polymerase iota Enzyme CHEMBL129795 CHEMBL1794483 (2)
0 / 0
Q6W5P4 Neuropeptide S receptor Neuropeptide receptor CHEMBL129795 CHEMBL1614052 (1)
1 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme CHEMBL129795 CHEMBL1614211 (2)
0 / 0
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL129795 CHEMBL1614421 (5) CHEMBL1614502 (1)
4 / 3
Q99549 M-phase phosphoprotein 8 Unclassified protein CHEMBL129795 CHEMBL1738402 (1)
0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein CHEMBL129795 CHEMBL2114908 (1)
0 / 0
P10721 Mast/stem cell growth factor receptor Kit Pdgfr CHEMBL129795 CHEMBL986519 (1)
4 / 4
P05412 Transcription factor AP-1 Transcription Factor CHEMBL129795 CHEMBL1913509 (1)
0 / 0
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL129795 CHEMBL1794536 (1)
0 / 0
P40225 Thrombopoietin Unclassified protein CHEMBL1395334 CHEMBL1614086 (1) CHEMBL1614034 (1)
1 / 1
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL129795 CHEMBL1738442 (3)
0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme CHEMBL129795 CHEMBL2354311 (1)
1 / 0
O00255 Menin Unclassified protein CHEMBL129795 CHEMBL1614257 (3) CHEMBL1614531 (1)
2 / 5
P23219 Prostaglandin G/H synthase 1 Oxidoreductase CHEMBL129795 CHEMBL763067 (1)
0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase CHEMBL129795 CHEMBL763067 (1)
0 / 3
P51531 Probable global transcription activator SNF2L2 Unclassified protein CHEMBL129795 CHEMBL2354206 (1)
1 / 0

CTD interaction (15)

compound gene gene name gene description interaction interaction type form reference
C040920 598 BCL2L1
BCL2-like 1 isoliquiritigenin results in decreased expression of BCL2L1 protein decreases expression
protein 15729620
C040920 329 BIRC2
baculoviral IAP repeat containing 2 isoliquiritigenin results in decreased expression of BIRC2 protein decreases expression
protein 15729620
C040920 330 BIRC3
baculoviral IAP repeat containing 3 isoliquiritigenin results in decreased expression of BIRC3 protein decreases expression
protein 15729620
C040920 836 CASP3
caspase 3, apoptosis-related cysteine peptidase (EC: isoliquiritigenin results in increased activity of CASP3 protein increases activity
protein 15729620
C040920 4792 NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha isoliquiritigenin results in decreased phosphorylation of NFKBIA protein decreases phosphorylation
protein 15729620
C040920 4792 NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha isoliquiritigenin results in increased expression of NFKBIA protein increases expression
protein 15729620
C040920 5970 RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A isoliquiritigenin affects the localization of RELA protein affects localization
protein 15729620
C040920 5970 RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A isoliquiritigenin results in decreased activity of RELA protein decreases activity
protein 15729620
C040920 6513 SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1 isoliquiritigenin inhibits the reaction [SLC2A1 protein affects the transport of Glucose] affects transport
/ decreases reaction
protein 14642735
C040920 6513 SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1 isoliquiritigenin results in decreased activity of SLC2A1 protein decreases activity
protein 14642735
C040920 54658 UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC: UGT1A1 protein results in increased glucuronidation of isoliquiritigenin increases glucuronidation
protein 14557274
C040920 54575 UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10 (EC: UGT1A10 protein results in increased glucuronidation of isoliquiritigenin increases glucuronidation
protein 14557274
C040920 54577 UGT1A7
UDP glucuronosyltransferase 1 family, polypeptide A7 (EC: UGT1A7 protein results in increased glucuronidation of isoliquiritigenin increases glucuronidation
protein 14557274
C040920 54576 UGT1A8
UDP glucuronosyltransferase 1 family, polypeptide A8 (EC: UGT1A8 protein results in increased glucuronidation of isoliquiritigenin increases glucuronidation
protein 14557274
C040920 54600 UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9 (EC: UGT1A9 protein results in increased glucuronidation of isoliquiritigenin increases glucuronidation
protein 14557274

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (83)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#207410 Antley-bixler syndrome without genital anomalies or disordered steroidogenesis; abs2 P21802
#101200 Apert syndrome P21802
#608584 Asthma-related traits, susceptibility to, 2 Q6W5P4
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#123790 Beare-stevenson cutis gyrata syndrome; bstvs P21802
#614592 Bent bone dysplasia syndrome; bbds P21802
#210900 Bloom syndrome; blm P54132
%606641 Body mass index; bmi P37231
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#609338 Carotid intimal medial thickness 1 P37231
#118300 Charcot-marie-tooth disease and deafness Q01453
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#118220 Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a Q01453
#114500 Colorectal cancer; crc P84022
#123500 Crouzon syndrome P21802
#127750 Dementia, lewy body; dlb P37840
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#133239 Esophageal cancer P04637
#600274 Frontotemporal dementia; ftd P10636
#606764 Gastrointestinal stromal tumor; gist P10721
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#137800 Glioma susceptibility 1; glm1 O75874
#139393 Guillain-barre syndrome, familial; gbs Q01453
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#602089 Hemangioma, capillary infantile P35968
#114550 Hepatocellular carcinoma P08581
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#145000 Hyperparathyroidism 1; hrpt1 O00255
#145900 Hypertrophic neuropathy of dejerine-sottas Q01453
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#147950 Hypogonadotropic hypogonadism 2 with or without anosmia; hh2 P11362
#603932 Intervertebral disc disease; idd P14780
#123150 Jackson-weiss syndrome; jws P21802
#149730 Lacrimoauriculodentodigital syndrome; ladd P21802
#601626 Leukemia, acute myeloid; aml P10721
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#162500 Neuropathy, hereditary, with liability to pressure palsies; hnpp Q01453
#601358 Nicolaides-baraitser syndrome; ncbrs P51531
#601665 Obesity P37231
#166250 Osteoglophonic dysplasia; ogd P11362
#260500 Papilloma of choroid plexus; cpp P04637
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#101600 Pfeiffer syndrome P11362
#172700 Pick disease of brain P10636
#172800 Piebald trait; pbt P10721
#605074 Renal cell carcinoma, papillary, 1; rccp1 P08581
#275210 Restrictive dermopathy, lethal P02545
#609579 Scaphocephaly, maxillary retrusion, and mental retardation P21802
#609620 Short qt syndrome 1; sqt1 Q12809
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#273300 Testicular germ cell tumor; tgct P10721
#187950 Thrombocythemia 1; thcyt1 P40225
#190440 Trigonocephaly 1; trigno1 P11362
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473


KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00016 Oral cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P00533 (related)
P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04637 (related)
P08581 (related)
P21802 (related)
H00022 Bladder cancer P00533 (related)
P04637 (related)
H00028 Choriocarcinoma P00533 (related)
P04637 (related)
H00030 Cervical cancer P00533 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
Q01453 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
P37231 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00066 Lewy body dementia (LBD) P04062 (related)
P37840 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P14780 (related)
P35354 (related)
H00026 Endometrial Cancer P04637 (related)
H00027 Ovarian cancer P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
P37231 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
P08581 (related)
P35354 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
P08581 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00003 Acute myeloid leukemia (AML) P10721 (related)
P10721 (marker)
H00170 Piebaldism P10721 (related)
H00023 Testicular cancer P10721 (marker)
H00255 Hypogonadotropic hypogonadism P11362 (related)
H00443 Osteoglophonic dysplasia (OD) P11362 (related)
H00458 Craniosynostosis P11362 (related)
P21802 (related)
H00516 Isolated orofacial clefts P11362 (related)
H01207 Trigonocephaly P11362 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00642 Lacrimo-auriculo-dento-digital syndrome (LADD) P21802 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00227 Congenital amegakaryocytic thrombocytopenia (CAMT) P40225 (marker)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
H01296 Hereditary neuropathy with liability to pressure palsies (HNPP) Q01453 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)

Diseases related to CTD interactions

3 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
D001927 C040920 Brain Diseases therapeutic
D009120 C040920 Muscle Cramp therapeutic
D009422 C040920 Nervous System Diseases therapeutic