Pterocarpus santalinus
Species
KNApSAcK Entry
| Organism name | Pterocarpus santalinus |
|---|---|
| Genus | Pterocarpus |
| Family | Fabaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Pterocarpus santalinus |
|---|---|
| Linked NCBI taxonomy ID | 1071199 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Fabaceae |
|---|---|
| ID | 3803 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Natural Activity
List (19)
| Species | Activity |
|---|---|
| Pterocarpus santalinus L. f. | Alexeteric |
| Pterocarpus santalinus L. f. | Analgesic |
| Pterocarpus santalinus L. f. | Anticonvulsant |
| Pterocarpus santalinus L. f. | Antidiabetic |
| Pterocarpus santalinus L. f. | Antiexudative |
| Pterocarpus santalinus L. f. | Antipyretic |
| Pterocarpus santalinus L. f. | Antispasmodic |
| Pterocarpus santalinus L. f. | Aphrodisiac |
| Pterocarpus santalinus L. f. | Astringent |
| Pterocarpus santalinus L. f. | CNS Depressant |
| Pterocarpus santalinus L. f. | Depurative |
| Pterocarpus santalinus L. f. | Diaphoretic |
| Pterocarpus santalinus L. f. | Expectorant |
| Pterocarpus santalinus L. f. | Fungicide |
| Pterocarpus santalinus L. f. | Hypoglycemic |
| Pterocarpus santalinus L. f. | Insecticide |
| Pterocarpus santalinus L. f. | Nematicide |
| Pterocarpus santalinus L. f. | Tonic |
| Pterocarpus santalinus L. f. | Tranquilizer |
Metabolite list (29)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00019424
|
5,3',4'-Trihydroxy-7-methoxyisoflavone 3'-O-glucoside
|
No. 2 | No. 15 |
|
||||
|
C00009459
|
Santal
/ 5,3',4'-Trihydroxy-7-methoxyisoflavone |
No. 3 | No. 15 |
|
||||
|
C00036622
|
6-Hydroxy-7,2',4',5'-tetramethoxyisoflavone
|
No. 8 | No. 15 |
|
||||
|
C00019047
|
6-Hydroxy-7,2',4',5'-tetramethoxyisoflavone
|
No. 8 | No. 15 |
|
||||
|
C00019065
|
Erythrodiol
/ 3beta-Erythrodiol |
CHEMBL298604
CHEMBL60687 CHEMBL400074 |
C077953
|
4 / 0 / 1 | No. 13 | No. 51 |
|
|
|
C00049120
|
beta-Amyrone
|
CHEMBL461060
|
No. 13 | No. 51 |
|
|||
|
C00003738
|
beta-Amyrin
/ beta-Amirin / beta-Amyrine / beta-Amyrenol |
C036380
|
0 / 4 | No. 23 | No. 51 |
|
||
|
C00029492
|
epi-Lupeol
/ 3-Epilupeol / (+)-epi-Lupeol |
CHEMBL289191
CHEMBL459702 |
3 / 0 / 0 | No. 23 | No. 51 |
|
||
|
C00003740
|
Betulin
|
CHEMBL23236
CHEMBL140040 CHEMBL1610940 CHEMBL2000891 CHEMBL2069124 |
C002503
|
18 / 16 / 17 | 0 / 2 | No. 23 | No. 51 |
|
|
C00003749
|
Lupeol
/ Lupenol / (+)-Lupenol |
CHEMBL289191
CHEMBL459702 |
C010480
|
3 / 0 / 0 | 2 / 6 | No. 23 | No. 51 |
|
|
C00019220
|
Lupenone
|
CHEMBL486393
CHEMBL575188 |
3 / 4 / 2 | No. 23 | No. 51 |
|
||
|
C00049211
|
Lup-20(29)-ene-2alpha,3beta-diol
|
CHEMBL1773216
|
No. 23 | No. 51 |
|
|||
|
C00019435
|
4',5-Dihydroxy-7-methoxyisoflavone 3'-O-(3''-E-cinnamoylglucoside)
|
No. 30 | No. 15 |
|
||||
|
C00023774
|
Fucostanol
/ Stigmasterol / Dihydro-beta-sitosterol / (24S)24-Ethylcholestain-3beta-ol |
CHEMBL66943
CHEMBL186373 CHEMBL400247 CHEMBL1568947 |
D013265
|
5 / 0 / 0 | 1 / 0 | No. 53 | No. 11 |
|
|
C00003672
|
Sitosterol
/ beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol |
CHEMBL221542
CHEMBL1398443 CHEMBL1875388 |
17 / 19 / 12 | No. 53 | No. 11 |
|
||
|
C00006925
|
Isoliquiritigenin
|
CHEMBL129795
CHEMBL1395334 |
C040920
|
59 / 83 / 90 | 12 / 3 | No. 92 | No. 13 |
|
|
C00011147
|
6,4'-Dihydroxyaurone 4-O-rutinoside
|
No. 169 | No. 13 |
|
||||
|
C00014665
|
6,4'-Dihydroxyaurone-4-O-neohesperidoside
|
No. 169 | No. 13 |
|
||||
|
C00002902
|
Pterostilbene
/ 3,5-Dimethoxy-4'-hydroxystilbene |
CHEMBL87712
CHEMBL83527 |
C107773
|
19 / 19 / 20 | 54 / 15 | No. 344 | No. 13 |
|
|
C00012772
|
Pterocarpdiolone
/ [4R-(4alpha,4aalpha,6beta,8abeta)]-Octahydro-4-hydroxy-6-(1-hydroxy-1-methylethyl)-4,8a-dimethyl-2(1H)-naphthalenone |
No. 351 |
|
|||||
|
C00012771
|
Pterocarptriol
/ [1R-(1alpha,3alpha,4abeta,7beta,8aalpha)]-Decahydro-7-(1-hydroxy-1-methylethyl)-1,4a-dimethyl-1,3-naphthalenediol |
No. 351 |
|
|||||
|
C00000856
|
4-Hydroxybenzoic acid
/ p-Hydroxybenzoic acid |
CHEMBL441343
|
C038193
|
21 / 7 / 16 | 2 / 1 | No. 817 | No. 81 |
|
|
C00002648
|
Gentisic acid
/ 2,5-Dihydroxybenzoic acid |
CHEMBL1461
|
C010925
|
15 / 6 / 8 | 2 / 1 | No. 817 | No. 81 |
|
|
C00002624
|
Savinin
/ (-)-Savinin / (-)-Hibalactone |
CHEMBL395263
CHEMBL459851 |
7 / 10 / 5 | No. 1029 | No. 21 |
|
||
|
C00002682
|
Vanillic acid
/ 3-Methoxy-4-hydroxybenzoic acid |
CHEMBL120568
|
D014641
|
5 / 3 / 3 | 5 / 0 | No. 1073 |
|
|
|
C00002776
|
Sinapic acid
|
CHEMBL109341
|
C073734
|
5 / 5 / 5 | 0 / 5 | No. 1366 | No. 6 |
|
|
C00011146
|
6-Hydroxy-5-methyl-3',4',5'-trimethoxyaurone-4-O-alpha-L-rhamnopyranoside
|
No. 3026 |
|
|||||
|
C00014668
|
6-Hydroxy-7-methyl-3',4',5'-trimethoxyaurone 4-O-rhamnoside
|
No. 3026 |
|
|||||
|
C00012855
|
Isopterocarpolone
/ [4aR-(4aalpha,6beta,8abeta)]-4a,5,6,7,8,8a-Hexahydro-6-(1-hydroxy-1-methylethyl)-4,8a-dimethyl-2(1H)-naphthalenone |
No. 3519 |
|
Human Protein / Gene in interactions
124 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00002648 C00003672 C00003740 C00006925 C00019065 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00002624 C00002648 C00002682 C00006925 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00002776 C00002902 C00003740 C00006925 | 0 / 3 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00003740 C00003749 C00023774 C00029492 | 0 / 0 |
| P08047 | Transcription factor Sp1 | Unclassified protein | C00003672 C00003749 C00029492 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00002682 C00006925 C00019065 | 0 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00002776 C00002902 C00006925 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00003672 C00003740 C00006925 | 1 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00003672 C00003740 C00006925 | 0 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00003672 C00003740 C00006925 | 1 / 1 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00002624 C00002902 C00006925 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00003672 C00003740 C00006925 | 0 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00003672 C00003740 C00006925 | 0 / 0 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00003740 C00003749 C00029492 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00003672 C00023774 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00000856 C00002648 | 0 / 1 |
| P03372 | Estrogen receptor | NR3A1 | C00002682 C00003672 | 1 / 1 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00002902 C00006925 | 0 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00003740 C00019220 | 0 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00003672 C00019220 | 4 / 2 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00000856 C00006925 | 1 / 8 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00003740 C00006925 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00002648 C00006925 | 2 / 2 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00002648 C00006925 | 0 / 0 |
| Q8TDU6 | G-protein coupled bile acid receptor 1 | Steroid-like ligand receptor | C00003740 C00019220 | 0 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00002902 C00006925 | 1 / 2 |
| P02545 | Prelamin-A/C | Unclassified protein | C00003740 C00006925 | 11 / 10 |
| P51580 | Thiopurine S-methyltransferase | Enzyme | C00000856 C00002682 | 1 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00002902 C00006925 | 4 / 3 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00000856 C00002648 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00002624 C00006925 | 1 / 1 |
| O75496 | Geminin | Unclassified protein | C00002902 C00006925 | 0 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00000856 C00002648 | 1 / 2 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00000856 C00002648 | 1 / 2 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00000856 C00002648 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00002624 C00006925 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00002902 C00003672 | 1 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00002624 C00006925 | 1 / 0 |
| O00255 | Menin | Unclassified protein | C00002902 C00006925 | 2 / 5 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00000856 C00002648 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00002624 C00002902 | 1 / 1 |
| Q9HAW7 | UDP-glucuronosyltransferase 1-7 | Enzyme | C00000856 | 0 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00006925 | 1 / 2 |
| Q9UQ49 | Sialidase-3 | Enzyme | C00000856 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00006925 | 2 / 3 |
| Q02156 | Protein kinase C epsilon type | Eta | C00003740 | 0 / 0 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00000856 | 0 / 0 |
| P34969 | 5-hydroxytryptamine receptor 7 | Serotonin receptor | C00023774 | 0 / 0 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00002776 | 2 / 2 |
| P51649 | Succinate-semialdehyde dehydrogenase, mitochondrial | Oxidoreductase | C00000856 | 1 / 1 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00003740 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00006925 | 0 / 0 |
| P42858 | Huntingtin | Unclassified protein | C00002682 | 1 / 1 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00006925 | 2 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00003740 | 3 / 1 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00002902 | 0 / 0 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00000856 | 0 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00002902 | 4 / 2 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00003672 | 3 / 2 |
| P37840 | Alpha-synuclein | Unclassified protein | C00006925 | 4 / 2 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00003672 | 0 / 0 |
| P55789 | FAD-linked sulfhydryl oxidase ALR | Enzyme | C00002902 | 1 / 0 |
| P03956 | Interstitial collagenase | M10A | C00002648 | 0 / 1 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00002624 | 7 / 3 |
| Q04206 | Transcription factor p65 | Transcription Factor | C00006925 | 0 / 0 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00003740 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00006925 | 0 / 0 |
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00006925 | 0 / 0 |
| P22894 | Neutrophil collagenase | M10A | C00002648 | 0 / 0 |
| P00734 | Prothrombin | S1A | C00003672 | 4 / 2 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00002902 | 2 / 2 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00000856 | 0 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00006925 | 5 / 3 |
| P80404 | 4-aminobutyrate aminotransferase, mitochondrial | Transferase | C00000856 | 1 / 1 |
| P12931 | Proto-oncogene tyrosine-protein kinase Src | Src | C00006925 | 0 / 0 |
| P35968 | Vascular endothelial growth factor receptor 2 | Vegfr | C00006925 | 1 / 0 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00000856 | 0 / 0 |
| P08581 | Hepatocyte growth factor receptor | TK tyrosine-protein kinase MET subfamily | C00006925 | 2 / 3 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00002902 | 1 / 1 |
| P04062 | Glucosylceramidase | Enzyme | C00006925 | 6 / 4 |
| P21802 | Fibroblast growth factor receptor 2 | TK tyrosine-protein kinase TLK subfamily | C00006925 | 9 / 3 |
| P08253 | 72 kDa type IV collagenase | M10A | C00002648 | 1 / 3 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00006925 | 3 / 3 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00006925 | 2 / 2 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00002902 | 1 / 1 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00006925 | 5 / 2 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00006925 | 0 / 0 |
| Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00000856 | 0 / 0 |
| Q13093 | Platelet-activating factor acetylhydrolase | Enzyme | C00002776 | 3 / 0 |
| P09884 | DNA polymerase alpha catalytic subunit | Transferase | C00023774 | 0 / 0 |
| P11362 | Fibroblast growth factor receptor 1 | Fgfr | C00006925 | 4 / 5 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00006925 | 0 / 0 |
| P05771 | Protein kinase C beta type | Alpha | C00003740 | 0 / 0 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00006925 | 2 / 2 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00006925 | 0 / 0 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00002648 | 0 / 0 |
| P14618 | Pyruvate kinase PKM | Enzyme | C00006925 | 0 / 0 |
| O60218 | Aldo-keto reductase family 1 member B10 | Enzyme | C00019065 | 0 / 0 |
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00006925 | 1 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00006925 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00003672 | 2 / 0 |
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00006925 | 0 / 0 |
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00000856 | 0 / 0 |
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00000856 | 0 / 0 |
| P10721 | Mast/stem cell growth factor receptor Kit | Pdgfr | C00006925 | 4 / 3 |
| P05412 | Transcription factor AP-1 | Transcription Factor | C00006925 | 0 / 0 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00000856 | 0 / 0 |
| P17706 | Tyrosine-protein phosphatase non-receptor type 2 | Tyr | C00019065 | 0 / 1 |
| P08254 | Stromelysin-1 | M10A | C00002648 | 1 / 0 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00000856 | 1 / 1 |
| P80365 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Enzyme | C00003672 | 1 / 1 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00006925 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002902 | 0 / 0 |
| P40225 | Thrombopoietin | Unclassified protein | C00006925 | 1 / 1 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00006925 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00003672 | 1 / 1 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00006925 | 7 / 37 |
| P42345 | Serine/threonine-protein kinase mTOR | Enzyme | C00006925 | 0 / 0 |
| P00519 | Tyrosine-protein kinase ABL1 | Abl | C00002902 | 1 / 2 |
| P11274 | Breakpoint cluster region protein | Bcr | C00002902 | 1 / 2 |
| Q02880 | DNA topoisomerase 2-beta | Isomerase | C00023774 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00002776 | 0 / 0 |
| P51531 | Probable global transcription activator SNF2L2 | Unclassified protein | C00006925 | 1 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00006925 | 0 / 0 |
70 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 6817 | SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) |
C00000856
C00002648
|
| 54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) |
C00002682
C00006925
|
| 54577 | UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G | UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) |
C00002682
C00006925
|
| 54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) |
C00002682
C00006925
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00002902
C00006925
|
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 |
C00002902
C00006925
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00002902
C00006925
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00002902
C00006925
|
| 4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00002902
|
| 329 | BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1 | baculoviral IAP repeat containing 2 |
C00006925
|
| 3952 | LEP, LEPD, OB, OBS | leptin |
C00000856
|
| 6513 | SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED | solute carrier family 2 (facilitated glucose transporter), member 1 |
C00006925
|
| 54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) |
C00006925
|
| 1499 | CTNNB1, CTNNB, MRD19, armadillo | catenin (cadherin-associated protein), beta 1, 88kDa |
C00003749
|
| 2539 | G6PD, G6PD1 | glucose-6-phosphate dehydrogenase (EC:1.1.1.49) |
C00002648
|
| 5728 | PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1 | phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) |
C00003749
|
| 54600 | UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I | UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) |
C00006925
|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00002902
|
| 23600 | AMACR, AMACRD, CBAS4, RACE, RM | alpha-methylacyl-CoA racemase (EC:5.1.99.4) |
C00002902
|
| 1386 | ATF2, CRE-BP1, CREB2, HB16, TREB7 | activating transcription factor 2 (EC:2.3.1.48) |
C00002902
|
| 578 | BAK1, BAK, BAK-LIKE, BCL2L7, CDN1 | BCL2-antagonist/killer 1 |
C00002902
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00002902
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00002902
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00002902
|
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00002902
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00002902
|
| 1027 | CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
C00002902
|
| 2921 | CXCL3, CINC-2b, GRO3, GROg, MIP-2b, MIP2B, SCYB3 | chemokine (C-X-C motif) ligand 3 |
C00002902
|
| 54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00002902
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00002902
|
| 1649 | DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153 | DNA-damage-inducible transcript 3 |
C00002902
|
| 56616 | DIABLO, DFNA64, SMAC | diablo, IAP-binding mitochondrial protein |
C00002902
|
| 1950 | EGF, HOMG4, URG | epidermal growth factor |
C00002902
|
| 1956 | EGFR, ERBB, ERBB1, HER1, PIG61, mENA | epidermal growth factor receptor (EC:2.7.10.1) |
C00002902
|
| 2002 | ELK1 | ELK1, member of ETS oncogene family |
C00002902
|
| 2523 | FUT1, H, HH, HSC | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) (EC:2.4.1.69) |
C00002902
|
| 9518 | GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB | growth differentiation factor 15 |
C00002902
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00002902
|
| 4670 | HNRNPM, CEAR, HNRNPM4, HNRPM, HNRPM4, HTGR1, NAGR1, hnRNP_M | heterogeneous nuclear ribonucleoprotein M |
C00002902
|
| 3313 | HSPA9, CSA, GRP-75, GRP75, HSPA9B, MOT, MOT2, MTHSP75, PBP74 | heat shock 70kDa protein 9 (mortalin) |
C00002902
|
| 3458 | IFNG, IFG, IFI | interferon, gamma |
C00002902
|
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00002902
|
| 3696 | ITGB8 | integrin, beta 8 |
C00002902
|
| 3717 | JAK2, JTK10, THCYT3 | Janus kinase 2 (EC:2.7.10.2) |
C00002902
|
| 3949 | LDLR, FH, FHC, LDLCQ2 | low density lipoprotein receptor |
C00002902
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00002902
|
| 1432 | MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA | mitogen-activated protein kinase 14 (EC:2.7.11.24) |
C00002902
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00002902
|
| 5599 | MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c | mitogen-activated protein kinase 8 (EC:2.7.11.24) |
C00002902
|
| 5601 | MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK | mitogen-activated protein kinase 9 (EC:2.7.11.24) |
C00002902
|
| 4170 | MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT | myeloid cell leukemia sequence 1 (BCL2-related) |
C00002902
|
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00002902
|
| 330 | BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 | baculoviral IAP repeat containing 3 |
C00006925
|
| 4790 | NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
C00002902
|
| 4843 | NOS2, HEP-NOS, INOS, NOS, NOS2A | nitric oxide synthase 2, inducible (EC:1.14.13.39) |
C00002902
|
| 8856 | NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR | nuclear receptor subfamily 1, group I, member 2 |
C00002902
|
| 9970 | NR1I3, CAR, CAR1, MB67 | nuclear receptor subfamily 1, group I, member 3 |
C00002902
|
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00002902
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00002902
|
| 6301 | SARS, SERRS, SERS | seryl-tRNA synthetase (EC:6.1.1.11) |
C00002902
|
| 6648 | SOD2, IPOB, MNSOD, MVCD6 | superoxide dismutase 2, mitochondrial (EC:1.15.1.1) |
C00002902
|
| 6667 | SP1 | Sp1 transcription factor |
C00002902
|
| 6774 | STAT3, APRF, HIES | signal transducer and activator of transcription 3 (acute-phase response factor) |
C00002902
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00002902
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00002902
|
| 9189 | ZBED1, ALTE, DREF, TRAMP, hDREF | zinc finger, BED-type containing 1 |
C00002902
|
| 118738 | ZNF488 | zinc finger protein 488 |
C00002902
|
| 10599 | SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6 | solute carrier organic anion transporter family, member 1B1 |
C00023774
|
| 4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) |
C00002682
|
| 54659 | UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C | UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) |
C00002682
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (135)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #207410 | Antley-bixler syndrome without genital anomalies or disordered steroidogenesis; abs2 |
P21802
|
| #101200 | Apert syndrome |
P21802
|
| #218030 | Apparent mineralocorticoid excess; ame |
P80365
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #600807 | Asthma, susceptibility to |
Q13093
|
| #608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #123790 | Beare-stevenson cutis gyrata syndrome; bstvs |
P21802
|
| #614592 | Bent bone dysplasia syndrome; bbds |
P21802
|
| #210900 | Bloom syndrome; blm |
P54132
|
| %606641 | Body mass index; bmi |
P37231
|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #614466 | Coronary heart disease, susceptibility to, 6; chds6 |
P08254
|
| #123500 | Crouzon syndrome |
P21802
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #133239 | Esophageal cancer |
P04637
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613163 | Gaba-transaminase deficiency |
P80404
|
| #606764 | Gastrointestinal stromal tumor; gist |
P10721
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P37231 |
| #232300 | Glycogen storage disease ii |
P10253
|
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #602089 | Hemangioma, capillary infantile |
P35968
|
| #114550 | Hepatocellular carcinoma |
P08581
|
| #143100 | Huntington disease; hd |
P42858
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #147950 | Hypogonadotropic hypogonadism 2 with or without anosmia; hh2 |
P11362
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #147050 | Ige responsiveness, atopic; iger |
Q13093
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #123150 | Jackson-weiss syndrome; jws |
P21802
|
| #149730 | Lacrimoauriculodentodigital syndrome; ladd |
P21802
|
| #601626 | Leukemia, acute myeloid; aml |
P10721
|
| #608232 | Leukemia, chronic myeloid; cml |
P00519
P11274 |
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04637 |
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #613076 | Myopathy, mitochondrial progressive, with congenital cataract, hearing loss, and developmental delay |
P55789
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #601358 | Nicolaides-baraitser syndrome; ncbrs |
P51531
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #601665 | Obesity |
P37231
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #166250 | Osteoglophonic dysplasia; ogd |
P11362
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P38398
|
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
P37840 |
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #101600 | Pfeiffer syndrome |
P11362
P21802 |
| #172700 | Pick disease of brain |
P10636
|
| #172800 | Piebald trait; pbt |
P10721
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #614278 | Platelet-activating factor acetylhydrolase deficiency; pafad |
Q13093
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #605074 | Renal cell carcinoma, papillary, 1; rccp1 |
P08581
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #609579 | Scaphocephaly, maxillary retrusion, and mental retardation |
P21802
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601367 | Stroke, ischemic |
P00734
|
| #271980 | Succinic semialdehyde dehydrogenase deficiency; ssadhd |
P51649
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #273300 | Testicular germ cell tumor; tgct |
P10721
|
| #610460 | Thiopurine s-methyltransferase deficiency |
P51580
|
| #187950 | Thrombocythemia 1; thcyt1 |
P40225
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #190440 | Trigonocephaly 1; trigno1 |
P11362
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (116)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
P04637 (marker) P08581 (related) Q16790 (marker) |
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
P00519
(related)
P00519 (marker) P11274 (related) P11274 (marker) Q03164 (related) Q03164 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
P00519
(related)
P00519 (marker) P04637 (related) P11274 (related) P11274 (marker) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04637 (related) P08581 (related) P21802 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04637 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04637 (related) P08253 (related) |
| H00030 | Cervical cancer |
P00533
(related)
|
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00223 | Inherited thrombophilia |
P00734
(related)
|
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04637 (related) |
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
P37840 (related) |
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P08253 (related) P14780 (related) P35354 (related) |
| H00027 | Ovarian cancer |
P04637
(related)
P38398 (related) |
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
P38398 (related) |
| H00032 | Thyroid cancer |
P04637
(related)
P37231 (related) |
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
P14679 (marker) |
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
P08581 (related) P35354 (related) |
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00003 | Acute myeloid leukemia (AML) |
P10721
(related)
P10721 (marker) |
| H00170 | Piebaldism |
P10721
(related)
|
| H00023 | Testicular cancer |
P10721
(marker)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00255 | Hypogonadotropic hypogonadism |
P11362
(related)
|
| H00443 | Osteoglophonic dysplasia (OD) |
P11362
(related)
|
| H00458 | Craniosynostosis |
P11362
(related)
P21802 (related) |
| H00516 | Isolated orofacial clefts |
P11362
(related)
|
| H01207 | Trigonocephaly |
P11362
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P11511
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00408 | Type I diabetes mellitus |
P17706
(related)
|
| H00642 | Lacrimo-auriculo-dento-digital syndrome (LADD) |
P21802
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00964 | Thiopurine S-methyltransferase deficiency (TPMT deficiency) |
P51580
(related)
|
| H00835 | Succinic semialdehyde dehydrogenase (SSADH) deficiency |
P51649
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00259 | Apparent mineralocorticoid excess syndrome |
P80365
(related)
|
| H01257 | GABA-transaminase deficiency |
P80404
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
Diseases related to CTD interactions
33 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D003110 | Colonic Neoplasms |
C00003740
C00002902 |
| D007249 | Inflammation |
C00003738
C00002902 |
| D006528 | Carcinoma, Hepatocellular |
C00003749
C00002902 |
| D012878 | Skin Neoplasms |
C00003749
C00002902 |
| D009422 | Nervous System Diseases |
C00006925
|
| D009374 | Neoplasms, Experimental |
C00003749
|
| D009202 | Cardiomyopathies |
C00003749
|
| D014947 | Wounds and Injuries |
C00003749
|
| D006461 | Hemolysis |
C00002648
|
| D005157 | Facial Pain |
C00003738
|
| D006930 | Hyperalgesia |
C00003738
|
| D064420 | Drug-Related Side Effects and Adverse Reactions |
C00003740
|
| D010146 | Pain |
C00003738
|
| D012220 | Rhinitis |
C00000856
|
| D001927 | Brain Diseases |
C00006925
|
| D009120 | Muscle Cramp |
C00006925
|
| D006937 | Hypercholesterolemia |
C00003749
|
| D000647 | Amnesia |
C00002776
|
| D000860 | Anoxia |
C00002776
|
| D001930 | Brain Injuries |
C00002776
|
| D056486 | Drug-Induced Liver Injury |
C00002776
|
| D004487 | Edema |
C00002776
|
| D058739 | Aberrant Crypt Foci |
C00002902
|
| D000236 | Adenoma |
C00002902
|
| D001943 | Breast Neoplasms |
C00002902
|
| D002471 | Cell Transformation, Neoplastic |
C00002902
|
| D015179 | Colorectal Neoplasms |
C00002902
|
| D015464 | Leukemia, Myelogenous, Chronic, BCR-ABL Positive |
C00002902
|
| D009361 | Neoplasm Invasiveness |
C00002902
|
| D009362 | Neoplasm Metastasis |
C00002902
|
| D012516 | Osteosarcoma |
C00002902
|
| D010190 | Pancreatic Neoplasms |
C00002902
|
| D010212 | Papilloma |
C00002902
|