PCIDB

KNApSAcK Metabolite C00002624

Metabolite

KNApSAcK Entry

id C00002624
Name Savinin / (-)-Savinin / (-)-Hibalactone
CAS RN 493-95-8
Standard InChI InChI=1S/C20H16O6/c21-20-15(6-13-2-4-17-19(8-13)26-11-24-17)14(9-22-20)5-12-1-3-16-18(7-12)25-10-23-16/h1-4,6-8,14H,5,9-11H2/b15-6+/t14-/m0/s1
Standard InChI (Main Layer) InChI=1S/C20H16O6/c21-20-15(6-13-2-4-17-19(8-13)26-11-24-17)14(9-22-20)5-12-1-3-16-18(7-12)25-10-23-16/h1-4,6-8,14H,5,9-11H2

Cluster

Phytochemical cluster No. 21
KCF-S cluster No. 1029

Link

ChEMBL

By standard InChI CHEMBL395263
By standard InChI Main Layer CHEMBL395263 CHEMBL459851

KEGG

By LinkDB C10880

CTD

By CAS RN

Species

Summary

Plant class

class name count
Spermatophyta 13
asterids 9
rosids 8
eudicotyledons 1

Family

family name count
Cupressaceae 12
Rutaceae 7
Araliaceae 4
Acanthaceae 3
Fabaceae 1
Plantaginaceae 1
Taxaceae 1
Ximeniaceae 1
Apiaceae 1

List (31)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Acanthopanax sessiliflorus 105886 Araliaceae asterids Viridiplantae
Amyris pinnata 1123434 Ximeniaceae eudicotyledons Viridiplantae
Anthriscus nemorosa 40886 Apiaceae asterids Viridiplantae
Calocedrus formosana 54798 Cupressaceae Spermatophyta Viridiplantae
Chamaecyparis formosensis 187461 Cupressaceae Spermatophyta Viridiplantae
Chamaecyparis obtusa 13415 Cupressaceae Spermatophyta Viridiplantae
Chamaecyparis pisifera 99808 Cupressaceae Spermatophyta Viridiplantae
Eleutherococcus divaricatus var. albeofructus 50304 Araliaceae asterids Viridiplantae
Eleutherococcus divaricatus var. chiisanensis 96666 Araliaceae asterids Viridiplantae
Eleutherococcus senticosus 82096 Araliaceae asterids Viridiplantae
Fagara heitzii 23513 Rutaceae rosids Viridiplantae
Hypoestes purpurea 13570 Acanthaceae asterids Viridiplantae
Juniperus chinensis 50182 Cupressaceae Spermatophyta Viridiplantae
Juniperus conferta 13102 Cupressaceae Spermatophyta Viridiplantae
Juniperus formosana var. concolor 13100 Cupressaceae Spermatophyta Viridiplantae
Juniperus oblonga 13100 Cupressaceae Spermatophyta Viridiplantae
Juniperus sabina 224740 Cupressaceae Spermatophyta Viridiplantae
Juniperus thurifera 177241 Cupressaceae Spermatophyta Viridiplantae
Justicia hyssopifolia 4190 Acanthaceae asterids Viridiplantae
Justicia neesii 4190 Acanthaceae asterids Viridiplantae
Libocedrus formosana 13594 Cupressaceae Spermatophyta Viridiplantae
Micranthemum umbrosum 69918 Plantaginaceae asterids Viridiplantae
Pterocarpus santalinus 1071199 Fabaceae rosids Viridiplantae
Ruta graveolens 37565 Rutaceae rosids Viridiplantae
Ruta microcarpa 452792 Rutaceae rosids Viridiplantae
Ruta pinnata 452794 Rutaceae rosids Viridiplantae
Taiwania cryptomerioides 50187 Cupressaceae Spermatophyta Viridiplantae
Taxus baccata 25629 Taxaceae Spermatophyta Viridiplantae
Zanthoxylum caudatum 67937 Rutaceae rosids Viridiplantae
Zanthoxylum naranjillo 67937 Rutaceae rosids Viridiplantae
Zanthoxylum pluviatile 67937 Rutaceae rosids Viridiplantae

Human Protein / Gene in interaction

7 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein CHEMBL395263 CHEMBL2114784 (1)
1 / 1
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL395263 CHEMBL2114788 (1)
0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein CHEMBL395263 CHEMBL2114817 (1)
7 / 3
Q9UNA4 DNA polymerase iota Enzyme CHEMBL395263 CHEMBL1794483 (1)
0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein CHEMBL395263 CHEMBL1738184 (1)
0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme CHEMBL395263 CHEMBL2354311 (1)
1 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein CHEMBL395263 CHEMBL2354287 (1)
1 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#137800 Glioma susceptibility 1; glm1 O75874
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (5)

KEGG disease name UniProt
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)