Species

KNApSAcK Entry

Organism name Hypoestes purpurea
Genus Hypoestes
Family Acanthaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Hypoestes
Linked NCBI taxonomy ID 13570
Linked level genus

Family

Family in NCBI taxonomy Acanthaceae
ID 4185

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00007211 External link 512 Helioxanthin
CHEMBL436474
No. 285 No. 21
C00043603 External link 512 Hypopurin D
/ (+)-Hypopurin D
CHEMBL521482
No. 294
C00042458 External link 512 Dehydroxycubebin
/ (-)-Dehydroxycubebin
CHEMBL487394
No. 629 No. 21
C00002608 External link 512 Hinokinin
/ Hinoquinin
/ (-)-Hinokinin
/ (-)-Hinoquinin
CHEMBL180970
CHEMBL182073
CHEMBL242011
C475934
2 / 1 / 1 No. 629 No. 21
C00002624 External link 512 Savinin
/ (-)-Savinin
/ (-)-Hibalactone
CHEMBL395263
CHEMBL459851
7 / 10 / 5 No. 1029 No. 21
C00043602 External link 512 Hypopurin C
/ (+)-Hypopurin C
No. 3204
C00043601 External link 512 Hypopurin B
/ (+)-Hypopurin B
CHEMBL484231
No. 3204
C00043600 External link 512 Hypopurin A
/ (+)-Hypopurin A
CHEMBL485667
No. 3204

Human Protein / Gene in interactions

9 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002608 1 / 0
Q99700 Ataxin-2 Unclassified protein C00002624 1 / 1
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00002624 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00002624 7 / 3
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002608 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00002624 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002624 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00002624 1 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00002624 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (11)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#608902 Drug metabolism, poor, cyp2d6-related P10635
#137800 Glioma susceptibility 1; glm1 O75874
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (6)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)