KCF-S cluster No. 30 (112 metabolites)

Corresponding Phytochemical cluster No. 15

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (112)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
rosids	76
asterids	68
eudicotyledons	17
Liliopsida	16
Spermatophyta	10
Magnoliophyta	4
Euphyllophyta	3

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Cumulative family count (Top 20)

class name	count
Lamiaceae	29
Vitaceae	17
Fabaceae	13
Eriocaulaceae	12
Asteraceae	11
Pinaceae	10
Fagaceae	9
Gentianaceae	7
Rosaceae	6
Cucurbitaceae	5
Polygonaceae	5
Theaceae	4
Acanthaceae	4
Ranunculaceae	4
Platanaceae	4
Salicaceae	4
Geraniaceae	4
Dennstaedtiaceae	3
Apocynaceae	3
Malvaceae	3

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Anthocyanidins and anthocyanins	6

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metabolites link (6)

br08003 Category	KEGG ID	KNApSAcK ID
Anthocyanidins and anthocyanins	C16368	C00006756
Anthocyanidins and anthocyanins	C16297	C00006757
Anthocyanidins and anthocyanins	C12095	C00006800
Anthocyanidins and anthocyanins	C16369	C00006801
Anthocyanidins and anthocyanins	C16370	C00006878
Anthocyanidins and anthocyanins	C16367	C00006879

Metabolite list (112)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00004170	Apigenin 7-(4''-Z-p-coumarylglucoside)
C00004171	Apigenin 7-(4''-E-p-coumarylglucoside)
C00004172	Echinacin / (-)-Echinacin / Apigenin 7-O-p-coumaroylglucoside / Apigenin 7-(6''-p-coumarylglucoside) / Apigenin 7-O-(6''-O-p-coumaroylglucoside)		C084441
C00004173	Apigenin 7-(6''-E-Caffeoylglucoside) / 7-[[6-O-[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
C00004183	Apigenin 7-glucoside-4'-p-coumarate
C00004184	Apigenin 7-glucoside-4'-trans-caffeate
C00004229	Scutellarein 7-glucuronide-6-ferulate
C00004312	Luteolin 7-(2''-p-coumaroylglucoside)
C00004323	Luteolin 7-(6''-E-cinnamylglucoside)
C00004324	Luteolin 7-(6''-p-coumarylglucoside)
C00004325	Luteolin 7-(6''-ferulylglucoside)
C00004354	Luteolin 3'-methyl ether 7-(3''-E-p-coumarylglucoside)
C00005839	Kaempferol 3-(2''-p-coumaryl-alpha-L-arabinopyranoside)
C00005842	Kaempferol 3-(6''-p-coumarylgalactoside)	CHEMBL266564 CHEMBL499705		2 / 1 / 2
C00005848	Kaempferol 3-(6''-(Z)-cinnamylglucoside)
C00005849	Kaempferol 3-(2''-p-coumarylglucoside)
C00005850	Kaempferol 3-(3''-p-coumarylglucoside)	CHEMBL448883
C00005851	Tiliroside / Potengriffioside A / Kaempferol 3-O-beta-D-(6''-coumaroyl)-glucopyranoside	CHEMBL266564 CHEMBL499705	C052083	2 / 1 / 2
C00005852	Kaempferol 3-(6''-ferulylglucoside) / 5,7-Dihydroxy-3-[[6-O-[3-(4-hydroxy-3-methoxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]oxy]-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
C00005853	Kaempferol 3-(4''-acetyl-6''-p-coumarylglucoside)
C00005863	Kaempferol 3-(2-(E)-p-coumarylrhamnoside) / 3-[[6-Deoxy-2-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-alpha-L-mannopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
C00005864	Kaempferol 3-(4''-p-coumarylrhamnoside)
C00005873	Biondnoid A / Buddlenoid A / Kaempferol 7-(6''-p-coumarylglucoside)	CHEMBL32646 CHEMBL449937		1 / 4 / 2
C00005933	Kaempferol 7,4'-dimethyl ether 3-(6''-(E)-p-coumarylglucoside)
C00005934	6-Hydroxykaempferol 7-(6''-(E)-caffeylglucoside)
C00005952	Quercetin 3-(6''-caffeylgalactoside)	CHEMBL451072
C00005959	Quercetin 3-(2''-p-coumarylglucoside)
C00005960	Quercetin 3-(3''-p-coumarylglucoside)
C00005961	Helichrysoside	CHEMBL437553	C084710
C00005962	Quercetin 3-(6''-ferulylglucoside)
C00005968	Quercetin 3-(2''-caffeylglucuronide)
C00006009	Isorhamnetin 3-(6''-p-coumarylglucoside)	CHEMBL233903
C00006011	Buddlenoid B / Isorhamnetin 7-(6''-p-coumarylglucoside) / 3,5-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-[[6-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]oxy]-4H-1-benzopyran-4-one	CHEMBL33244		1 / 4 / 2
C00006032	Quercetagetin 4'-methyl ether 7-(6-(E)-caffeylglucoside)
C00006257	Isoorientin 2''-p-hydroxybenzoate
C00006258	Vitexin 2''-p-hydroxybenzoate
C00006298	Isoorientin 2''-O-(E)-p-coumarate
C00006299	2''-trans-Caffeoylisoorientin / Isoorientin 2''-O-(E)-caffeate
C00006301	Vitexin 2''-O-p-coumarate
C00006302	Isoorientin 2''-O-(E)-ferulate / trans-Feruloyl-2''-isoorientin
C00006303	Vitexin 2''-O-(E)-ferulate
C00006379	Orientin 7-O-caffeate
C00006753	Apigeninidin 5-(5''-caffeylarabinoside)
C00006756	Pelargonidin 3-p-coumarylglucoside
C00006757	Pelargonidin 3-(6''-caffeylglucoside)
C00006800	Hyacinthin / Cyanidin 3-(6-O-p-coumarylglucoside)
C00006801	Cyanidin 3-(6''-caffeylglucoside)
C00006861	Peonidin 3-(6''-p-coumarylglucoside)
C00006862	Peonidin 3-(6''-caffeylgucoside)
C00006878	Delphinidin 3-(6''-p-coumarylglucoside)
C00006879	Delphinidin 3-caffeylglucoside
C00006896	Petunidin 3-(6''-p-coumarylglucoside)
C00006903	Malvidin 3-(6''-p-coumarylglucoside)
C00006904	Malvidin 3-(6''-p-caffeyglucoside)
C00010159	Formononetin 7-O-(2''-p-hydroxybenzoylglucoside)
C00010164	Genistein 7-O-(2''-p-coumaroylglucoside)
C00010173	4'-O-Methylneobavaisoflavone 7-O-(2''-p-coumaroylglucoside)	CHEMBL453212	C064335
C00011107	Delphinidin 3-O-beta-D-(6-O-(E)-p-coumaryl)galactopyranoside
C00011121	2''-O-Vanilloylvitexin
C00011122	2''-O-Feruloylorientin
C00011166	2''-O-p-Hydroxybenzoylorientin
C00011175	Myricetin 3'-O-(6''-p-coumaroyl)glucoside
C00013614	Echitin / (-)-Echitin / Echitin(glycoside) / Apigenin 7-(2''-E-p-coumaroylglucoside / (E)-5-Hydroxy-2-(4-hydroxyphenyl)-7-[[2-O-[3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]oxy]-4H-1-benzopyran-4-one
C00013615	Apigenin 7-(3''-p-coumaroylglucoside)	CHEMBL234317
C00013616	Apigenin 7-(6''-E-p-coumaroylgalactoside) / 5-Hydroxy-2-(4-hydroxyphenyl)-7-[[6-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-beta-D-galactopyranosyl]oxy]-4H-1-benzopyran-4-one
C00013619	Apigenin 7-(3''-acetyl-6''-E-p-coumaroylglucoside) / 7-[[3-O-Acetyl-6-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-b-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
C00013637	Hispidulin 7-(6''-E-p-Coumaroylglucoside) / 5-Hydroxy-2-(4-hydroxyphenyl)-7-[[6-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]oxy]-6-methoxy-4H-1-benzopyran-4-one
C00013643	8-Hydroxyapigenin 8-(6''-E-p-coumaroylglucoside) / 5,7-Dihydroxy-2-(4-hydroxyphenyl)-8-[[6-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]oxy]-4H-1-benzopyran-4-one
C00013654	Skullcapflavone I 2'-(2''-E-cinnamoylglucoside) / 5-Hydroxy-7,8-dimethoxy-2-[2-[[2-O-[(2E)-1-oxo-3-phenyl-2-propenyl]-beta-D-glucopyranosyl]oxy]phenyl]-4H-1-benzopyran-4-one
C00013655	Skullcapflavone I 2'-(4''-E-Cinnamoylglucoside) / 5-Hydroxy-7,8-dimethoxy-2-[2-[[4-O-[(2E)-1-oxo-3-phenyl-2-propenyl]-beta-D-glucopyranosyl]oxy]phenyl]-4H-1-benzopyran-4-one
C00013666	Luteolin 7-(6''-p-benzoyglucoside)
C00013678	Chrysoeriol 7-(3''-Z-p-coumaroylglucoside) / 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-[[3-O-[(2Z)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]oxy]-4H-1-benzopyran-4-one
C00013690	Spicoside A / 6-Hydroxyluteolin 7-(6''-(E)-caffeoylglucoside) / 2-(3,4-Dihydroxyphenyl)-7-[[6-O-[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]oxy]-5,6-dihydroxy-4H-1-benzopyran-4-one
C00013769	Kaempferol 3-(2''-(E)-p-coumaroyl-alpha-L-arabinofuranoside) / 5,7-Dihydroxy-2-(4-hydroxyphenyl)-3-[[2-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-alpha-L-arabinofuranosyl]oxy]-4H-1-benzopyran-4-one
C00013770	Kaempferol 3-(2''-(Z)-p-coumaroylrhamnoside) / (Z)-3-[[6-Deoxy-2-O-[3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-alpha-L-mannopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
C00013771	Kaempferol 3-(2''-(Z)-p-coumaroylglucoside) / 5,7-Dihydroxy-2-(4-hydroxyphenyl)-3-[[2-O-[(2Z)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]oxy]-4H-1-benzopyran-4-one
C00013772	Kaempferol 3-(4''-p-coumaroylglucoside) / 5,7-Dihydroxy-2-(4-hydroxyphenyl)-3-[[4-O-[3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]oxy]-4H-1-benzopyran-4-one
C00013773	Kaempferol 3-(6''-caffeoylglucoside) / 3-[[6-O-[(2E)-3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one	CHEMBL503602 CHEMBL2071308
C00013774	Kaempferol 3-(5''-feruloylapioside) / [3S-[3alpha,3(E),4alpha,5beta]]-3-(4-Hydroxy-3-methoxyphenyl)-, [5-[[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-3-yl]oxy]tetrahydro-3,4-dihydroxy-3-furanyl]methyl ester 2-propenoic acid
C00013777	Dentatiflavonoid / Kaempferol 3-(2''-(E)-p-coumaroyl-6''-acetylglucoside) / 3-[[6-O-Acetyl-2-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
C00013778	Kaempferol 3-(3''-acetyl-6''-p-coumaroylglucoside) / 3-[[3-O-Acetyl-6-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
C00013825	6-Hydroxykaempferol 6-methyl ether 3-(6''-p-coumaroylglucoside) / 5,7-Dihydroxy-2-(4-hydroxyphenyl)-3-[[6-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]oxy]-6-methoxy-4H-1-benzopyran-4-one	CHEMBL2037059
C00013831	Herbacetin 7-methyl ether 3-(2''-(E)-feruloylglucoside) / 5,8-Dihydroxy-3-[[2-O-[(2E)-3-(4-hydroxy-3-methoxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]oxy]-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one
C00013863	Quercetin 3-(6''-feruloylgalactoside) / Quercetin 3-O-(6''-feruloyl)-beta-D-galactopyranoside / 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-[[6-O-[(2E)-3-(4-hydroxy-3-methoxyphenyl)-1-oxo-2-propenyl]-beta-D-galactopyranosyl]oxy]-4H-1-benzopyran-4-one
C00013943	Quercetagetin 7-(6''-(E)-caffeoylglucoside) / 6-Hydroxyquercetin 7-(6''-(E)-caffeoylglucoside) / 2-(3,4-Dihydroxyphenyl)-7-[[6-O-[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]oxy]-3,5,6-trihydroxy-4H-1-benzopyran-4-one
C00013944	Patuletin 3-(6''-p-coumaroylglucoside) / Quercetagetin 6-methyl ether 3-(6''-p-coumaroylglucoside) / 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-[[6-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]oxy]-6-methoxy-4H-1-benzopyran-4-one
C00013945	Patuletin 3-(6''-(E)-feruloylglucoside) / Quercetagetin 6-methyl ether 3-(6''-(E)-feruloylglucoside) / 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[[6-O-[(2E)-3-(4-hydroxy-3-methoxyphenyl)-1-oxo-2-propenyl]-b-D-glucopyranosyl]oxy]-6-methoxy-4H-1-Benzopyran-4-one
C00013972	Myricetin 3-(6''-p-coumaroylglucoside)
C00014014	Cucumerin B
C00014015	Cucumerin A / 8-beta-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[1-(4-hydroxyphenyl)ethyl]-4H-1-benzopyran-4-one
C00014084	2''-O-Galloylisovitexin
C00014088	Vitexin 2''-O-gallate
C00014098	Isoorientin 2''-O-gallate
C00014100	Isoorientin 6''-O-caffeate
C00014101	Perfoliatumin A / Isoorientin 6''-O-p-hydroxybenzoate
C00014102	Perfoliatumin B / Isoorientin 6''-O-p-methoxybenzoate
C00014103	Orientin 2''-O-caffeate
C00014104	Orientin 2''-O-gallate
C00014106	Isoscoparin 2''-O-ferulate
C00014875	Hirsutidin 3-O-(6-O-p-coumaroyl)glucoside
C00019435	4',5-Dihydroxy-7-methoxyisoflavone 3'-O-(3''-E-cinnamoylglucoside)
C00019588	7-Hydroxy-5,6,6'-trimethoxy-3',4'-methylenedioxyisoflavone 7-O-(2''-p-coumaroylglucoside)
C00020411	Delphinidin 3-(3''-p-coumaroylglucoside)
C00029430	2''-(4'''-Hydroxybenzoyl)-isoorientin
C00031603	Apigenin 7-O-beta-D-(6-O-p-coumaroyl)glucopyranoside / Apigenin 7-O-[6-O-p-(Z)-coumaroyl]-.beta.-D-glucopyranoside
C00032999	Gladiatoside C2
C00034908	Tribuloside / Tribuloside A	CHEMBL266564 CHEMBL499705		2 / 1 / 2
C00038223	2'-Benzoylmangiferin	CHEMBL466996
C00038475	Apigenin 7-O-(3-O-p-(Z)-coumaroyl)-beta-D-glucopyranoside	CHEMBL234317
C00038476	Apigenin 7-O-(6-O-p-(Z)-coumaroyl)-beta-D-glucopyranoside
C00043637	Kunzeachromone C / (-)-Kunzeachromone C
C00043639	Kunzeachromone E / (-)-Kunzeachromone E

Human Protein / Gene in interactions

3 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00005842 C00005851 C00034908	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00005842 C00005851 C00034908	0 / 1
P14679	Tyrosinase	Oxidoreductase	C00005873 C00006011	4 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions