Lespedeza bicolor

• Index
• Plant Species
• Metabolite list (12)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Lespedeza bicolor
Genus	Lespedeza
Family	Fabaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Lespedeza bicolor
Linked NCBI taxonomy ID	556514
Linked level	species

Family

Family in NCBI taxonomy	Fabaceae
ID	3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (12)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00018971	7,4'-Dihydroxy-2'-methoxy-6-geranylisoflavanone					No. 19	No. 14
C00001055	Isoorientin / Homoorientin / Lespecapitioside / Luteolin 6-C-beta-D-glucopyranoside / 2-(3,4-Dihydroxyphenyl)-6-beta-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one	CHEMBL239559 CHEMBL1302308	C057912	23 / 14 / 17	0 / 1	No. 22	No. 15
C00003740	Betulin	CHEMBL23236 CHEMBL140040 CHEMBL1610940 CHEMBL2000891 CHEMBL2069124	C002503	18 / 16 / 17	0 / 2	No. 23	No. 51
C00003741	Betulinic acid	CHEMBL269277 CHEMBL71690 CHEMBL519059 CHEMBL1318530 CHEMBL2005635	C002070	34 / 17 / 14	10 / 2	No. 23	No. 51
C00018972	2',4'-Dihydroxy-6''-(4-methyl-3-pentenyl)-6''-methylpyrano[2'',3'':7,6]isoflavanone					No. 39
C00003672	Sitosterol / beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol	CHEMBL221542 CHEMBL1398443 CHEMBL1875388		17 / 19 / 12		No. 53	No. 11
C00009380	Daidzein / 7,4'-Dihydroxyisoflavone	CHEMBL8145	C004742	60 / 68 / 76	113 / 12	No. 71	No. 15
C00006925	Isoliquiritigenin	CHEMBL129795 CHEMBL1395334	C040920	59 / 83 / 90	12 / 3	No. 92	No. 13
C00002668	Protocatechuic acid / 3,4-Dihydroxybenzoic acid	CHEMBL37537	C009091	33 / 19 / 19	2 / 0	No. 817	No. 81
C00002759	Methyl caffeate	CHEMBL17001	C042405			No. 876
C00000615	Caffeic acid	CHEMBL145 CHEMBL1320034		68 / 64 / 63		No. 904	No. 6
C00001402	Bufotenine	CHEMBL416526	D002027	6 / 3 / 0		No. 1385	No. 4

Human Protein / Gene in interactions

169 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000615 C00003672 C00003740 C00003741 C00006925 C00009380	1 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000615 C00003672 C00003740 C00003741 C00006925 C00009380	1 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000615 C00003672 C00003740 C00003741 C00006925 C00009380	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000615 C00003672 C00003740 C00003741 C00006925 C00009380	0 / 1
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000615 C00003672 C00003740 C00003741 C00006925 C00009380	0 / 1
P02545	Prelamin-A/C	Unclassified protein	C00000615 C00003740 C00003741 C00006925 C00009380	11 / 10
P06746	DNA polymerase beta	Enzyme	C00000615 C00001055 C00002668 C00003672 C00003741	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00000615 C00001055 C00002668 C00006925 C00009380	4 / 3
P15121	Aldose reductase	Enzyme	C00000615 C00002668 C00003741 C00006925	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00000615 C00001055 C00001402 C00002668	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00000615 C00001055 C00006925 C00009380	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00000615 C00003672 C00003740 C00006925	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00000615 C00003741 C00006925 C00009380	0 / 0
P03372	Estrogen receptor	NR3A1	C00000615 C00002668 C00003672 C00009380	1 / 1
Q9UBT6	DNA polymerase kappa	Enzyme	C00000615 C00001055 C00003741 C00006925	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00000615 C00001055 C00002668 C00009380	0 / 0
O75496	Geminin	Unclassified protein	C00002668 C00003741 C00006925 C00009380	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00000615 C00001055 C00003672 C00009380	1 / 1
Q01453	Peripheral myelin protein 22	Unclassified protein	C00000615 C00006925 C00009380	5 / 2
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001055 C00006925 C00009380	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000615 C00003740 C00006925	0 / 3
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00000615 C00006925 C00009380	1 / 8
P11387	DNA topoisomerase 1	Isomerase	C00003740 C00003741 C00009380	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00003740 C00003741 C00009380	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00000615 C00001055 C00002668	1 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00003672 C00003741 C00009380	2 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00000615 C00006925 C00009380	2 / 2
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000615 C00006925 C00009380	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00000615 C00006925 C00009380	3 / 3
O00255	Menin	Unclassified protein	C00000615 C00001055 C00006925	2 / 5
P10828	Thyroid hormone receptor beta	NR1A2	C00000615 C00003740 C00009380	3 / 1
P14780	Matrix metalloproteinase-9	M10A	C00000615 C00002668 C00006925	2 / 2
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00000615 C00003740 C00003741	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00001055 C00002668 C00006925	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000615 C00001055 C00006925	1 / 2
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00003740 C00003741	0 / 0
Q8TDU6	G-protein coupled bile acid receptor 1	Steroid-like ligand receptor	C00003740 C00003741	0 / 0
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00001055 C00006925	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00000615 C00003672	3 / 2
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00000615 C00009380	1 / 1
O75164	Lysine-specific demethylase 4A	Enzyme	C00000615 C00001055	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00000615 C00002668	1 / 2
P43166	Carbonic anhydrase 7	Lyase	C00000615 C00002668	0 / 0
P05771	Protein kinase C beta type	Alpha	C00003740 C00003741	0 / 0
Q02156	Protein kinase C epsilon type	Eta	C00003740 C00003741	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00006925 C00009380	0 / 0
P22748	Carbonic anhydrase 4	Lyase	C00000615 C00002668	1 / 1
Q13093	Platelet-activating factor acetylhydrolase	Enzyme	C00000615 C00002668	3 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00000615 C00006925	2 / 2
Q9GZT9	Egl nine homolog 1	Enzyme	C00000615 C00002668	1 / 1
P54132	Bloom syndrome protein	Enzyme	C00006925 C00009380	1 / 2
P40225	Thrombopoietin	Unclassified protein	C00006925 C00009380	1 / 1
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00000615 C00002668	0 / 0
P14618	Pyruvate kinase PKM	Enzyme	C00006925 C00009380	0 / 0
O60218	Aldo-keto reductase family 1 member B10	Enzyme	C00000615 C00003741	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00006925 C00009380	1 / 1
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000615 C00006925	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00000615 C00001055	0 / 0
P23280	Carbonic anhydrase 6	Lyase	C00000615 C00002668	0 / 0
Q9ULX7	Carbonic anhydrase 14	Lyase	C00000615 C00002668	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00000615 C00009380	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00003741 C00006925	1 / 0
O43570	Carbonic anhydrase 12	Lyase	C00000615 C00002668	1 / 2
P04637	Cellular tumor antigen p53	Transcription Factor	C00006925 C00009380	7 / 37
Q16790	Carbonic anhydrase 9	Lyase	C00000615 C00002668	0 / 1
Q13951	Core-binding factor subunit beta	Unclassified protein	C00001055 C00002668	0 / 1
P39748	Flap endonuclease 1	Enzyme	C00001055 C00006925	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00000615 C00006925	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00003740 C00003741	0 / 0
Q01196	Runt-related transcription factor 1	Unclassified protein	C00001055 C00002668	1 / 4
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00006925 C00009380	5 / 3
P14679	Tyrosinase	Oxidoreductase	C00000615 C00003672	4 / 2
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00003740 C00006925	0 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00001055 C00009380	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00000615 C00002668	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00003672 C00003741	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00006925 C00009380	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00003741 C00006925	0 / 0
P03956	Interstitial collagenase	M10A	C00000615 C00002668	0 / 1
Q04206	Transcription factor p65	Transcription Factor	C00003741 C00006925	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00001055 C00003741	1 / 1
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00001055 C00002668	0 / 0
P08253	72 kDa type IV collagenase	M10A	C00000615 C00002668	1 / 3
P37059	Estradiol 17-beta-dehydrogenase 2	Enzyme	C00009380	0 / 0
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00003741	0 / 0
Q9NPD5	Solute carrier organic anion transporter family member 1B3	Electrochemical transporter	C00009380	1 / 0
P07711	Cathepsin L1	C1A	C00002668	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00009380	0 / 1
P00734	Prothrombin	S1A	C00003672	4 / 2
P04150	Glucocorticoid receptor	NR3C1	C00009380	0 / 1
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00009380	2 / 2
P41143	Delta-type opioid receptor	Opioid receptor	C00009380	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00001402	2 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00009380	0 / 0
P12931	Proto-oncogene tyrosine-protein kinase Src	Src	C00006925	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00000615	1 / 1
P04745	Alpha-amylase 1	Enzyme	C00009380	0 / 0
P35968	Vascular endothelial growth factor receptor 2	Vegfr	C00006925	1 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00006925	2 / 0
Q13133	Oxysterols receptor LXR-alpha	NR1H3	C00003741	0 / 0
P08581	Hepatocyte growth factor receptor	TK tyrosine-protein kinase MET subfamily	C00006925	2 / 3
P35236	Tyrosine-protein phosphatase non-receptor type 7	Tyr	C00000615	0 / 0
P08151	Zinc finger protein GLI1	Unclassified protein	C00003741	0 / 0
Q8TDS4	Hydroxycarboxylic acid receptor 2	Hydroxycarboxylic acid receptor	C00000615	0 / 0
P42330	Aldo-keto reductase family 1 member C3	Enzyme	C00000615	0 / 0
P16581	E-selectin	Adhesion	C00002668	0 / 0
P55055	Oxysterols receptor LXR-beta	NR1H3	C00003741	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00009380	0 / 0
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00009380	2 / 0
Q04828	Aldo-keto reductase family 1 member C1	Enzyme	C00000615	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00006925	2 / 3
O15118	Niemann-Pick C1 protein	Unclassified protein	C00009380	1 / 1
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00001055	1 / 0
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00009380	0 / 0
P15559	NAD(P)H dehydrogenase [quinone] 1	Enzyme	C00003741	0 / 0
P08183	Multidrug resistance protein 1	drug	C00003672	1 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00001402	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00001402	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00009380	0 / 0
P11362	Fibroblast growth factor receptor 1	Fgfr	C00006925	4 / 5
P51452	Dual specificity protein phosphatase 3	Ser_Thr_Tyr	C00000615	0 / 0
P02768	Serum albumin	Secreted protein	C00002668	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00006925	0 / 0
P14151	L-selectin	Adhesion	C00002668	0 / 0
P16109	P-selectin	Adhesion	C00002668	1 / 0
P05091	Aldehyde dehydrogenase, mitochondrial	Oxidoreductase	C00009380	1 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00006925	0 / 0
P37840	Alpha-synuclein	Unclassified protein	C00006925	4 / 2
P08047	Transcription factor Sp1	Unclassified protein	C00003672	0 / 0
Q6W5P4	Neuropeptide S receptor	Neuropeptide receptor	C00006925	1 / 0
P52895	Aldo-keto reductase family 1 member C2	Enzyme	C00000615	1 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00009380	0 / 0
Q06124	Tyrosine-protein phosphatase non-receptor type 11	Tyr	C00000615	4 / 2
P22894	Neutrophil collagenase	M10A	C00002668	0 / 0
Q99549	M-phase phosphoprotein 8	Unclassified protein	C00006925	0 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00000615	0 / 0
P08908	5-hydroxytryptamine receptor 1A	Serotonin receptor	C00001402	1 / 0
P10275	Androgen receptor	NR3C4	C00009380	3 / 4
P28221	5-hydroxytryptamine receptor 1D	Serotonin receptor	C00001402	0 / 0
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00009380	0 / 0
P10721	Mast/stem cell growth factor receptor Kit	Pdgfr	C00006925	4 / 3
P05412	Transcription factor AP-1	Transcription Factor	C00006925	0 / 0
P07451	Carbonic anhydrase 3	Lyase	C00000615	0 / 0
P35869	Aryl hydrocarbon receptor	Transcription Factor	C00009380	0 / 0
P08254	Stromelysin-1	M10A	C00002668	1 / 0
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00000615	0 / 0
P80365	Corticosteroid 11-beta-dehydrogenase isozyme 2	Enzyme	C00003672	1 / 1
Q12794	Hyaluronidase-1	Enzyme	C00000615	1 / 2
P04062	Glucosylceramidase	Enzyme	C00006925	6 / 4
P24298	Alanine aminotransferase 1	Enzyme	C00000615	0 / 0
P21802	Fibroblast growth factor receptor 2	TK tyrosine-protein kinase TLK subfamily	C00006925	9 / 3
P21728	D(1A) dopamine receptor	Dopamine receptor	C00006925	0 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00009380	0 / 0
Q9Y6L6	Solute carrier organic anion transporter family member 1B1	Electrochemical transporter	C00009380	1 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00009380	4 / 1
Q8IUX4	DNA dC->dU-editing enzyme APOBEC-3F	Enzyme	C00003741	0 / 0
P17516	Aldo-keto reductase family 1 member C4	Enzyme	C00000615	1 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00009380	3 / 0
P33527	Multidrug resistance-associated protein 1	drugs	C00009380	0 / 0
P07900	Heat shock protein HSP 90-alpha	Other cytosolic protein	C00000615	0 / 0
P08238	Heat shock protein HSP 90-beta	Other cytosolic protein	C00000615	0 / 0
Q9UBT2	SUMO-activating enzyme subunit 2	Enzyme	C00003741	0 / 0
Q9UBE0	SUMO-activating enzyme subunit 1	Unclassified protein	C00003741	0 / 0
P27338	Amine oxidase [flavin-containing] B	Oxidoreductase	C00009380	0 / 0
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00009380	1 / 1
P14061	Estradiol 17-beta-dehydrogenase 1	Enzyme	C00009380	0 / 0
P42345	Serine/threonine-protein kinase mTOR	Enzyme	C00006925	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00001055	2 / 1
P51531	Probable global transcription activator SNF2L2	Unclassified protein	C00006925	1 / 0

124 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00003741 C00006925 C00009380
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00003741 C00009380
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00006925 C00009380
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00006925 C00009380
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00006925 C00009380
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00003741 C00009380
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00006925 C00009380
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00003741 C00009380
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00006925 C00009380
6513	SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED	solute carrier family 2 (facilitated glucose transporter), member 1	C00006925 C00009380
1312	COMT	catechol-O-methyltransferase (EC:2.1.1.6)	C00002668 C00009380
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00006925 C00009380
5747	PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK	protein tyrosine kinase 2 (EC:2.7.10.2)	C00009380
10057	ABCC5, ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	C00009380
119	ADD2, ADDB	adducin 2 (beta)	C00009380
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00009380
249	ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP	alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1)	C00009380
251	ALPPL2, ALPG, ALPPL, GCAP	alkaline phosphatase, placental-like 2 (EC:3.1.3.1)	C00009380
367	AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM	androgen receptor	C00009380
396	ARHGDIA, GDIA1, NPHS8, RHOGDI, RHOGDI-1	Rho GDP dissociation inhibitor (GDI) alpha	C00009380
23545	ATP6V0A2, A2, ARCL, ARCL2A, ATP6A2, ATP6N1D, J6B7, RTF, STV1, TJ6, TJ6M, TJ6S, VPH1, WSS	ATPase, H+ transporting, lysosomal V0 subunit a2 (EC:3.6.3.6)	C00009380
11177	BAZ1A, ACF1, WALp1, WCRF180, hACF1	bromodomain adjacent to zinc finger domain, 1A	C00009380
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00009380
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00009380
632	BGLAP, BGP, OC, OCN	bone gamma-carboxyglutamate (gla) protein	C00009380
672	BRCA1, BRCAI, BRCC1, BROVCA1, IRIS, PNCA4, PPP1R53, PSCP, RNF53	breast cancer 1, early onset	C00009380
103993			C00009380
890	CCNA2, CCN1, CCNA	cyclin A2	C00009380
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00009380
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00009380
1019	CDK4, CMM3, PSK-J3	cyclin-dependent kinase 4 (EC:2.7.11.22)	C00009380
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00009380
1103	CHAT, CHOACTASE, CMS1A, CMS1A2	choline O-acetyltransferase (EC:2.3.1.6)	C00009380
1152	CKB, B-CK, CKBB	creatine kinase, brain (EC:2.7.3.2)	C00009380
19	ABCA1, ABC-1, ABC1, CERP, HDLDT1, TGD	ATP-binding cassette, sub-family A (ABC1), member 1	C00009380
9167	COX7A2L, COX7AR, COX7RP, EB1, SIG81	cytochrome c oxidase subunit VIIa polypeptide 2 like	C00009380
1374	CPT1A, CPT1, CPT1-L, L-CPT1	carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21)	C00009380
1401	CRP, PTX1	C-reactive protein, pentraxin-related	C00009380
6387	CXCL12, IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1, SDF1A, SDF1B	chemokine (C-X-C motif) ligand 12	C00009380
1588	CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM	cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00009380
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00009380
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00009380
1589	CYP21A2, CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B	cytochrome P450, family 21, subfamily A, polypeptide 2 (EC:1.14.99.10)	C00009380
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00009380
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00009380
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00009380
1795	DOCK3, MOCA, PBP	dedicator of cytokinesis 3	C00009380
1846	DUSP4, HVH2, MKP-2, MKP2, TYP	dual specificity phosphatase 4 (EC:3.1.3.16 3.1.3.48)	C00009380
9166	EBAG9, EB9, PDAF	estrogen receptor binding site associated, antigen, 9	C00009380
2027	ENO3, GSD13, MSE	enolase 3 (beta, muscle) (EC:4.2.1.11)	C00009380
2041	EPHA1, EPH, EPHT, EPHT1	EPH receptor A1 (EC:2.7.10.1)	C00009380
83715	ESPN, DFNB36	espin	C00009380
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00009380
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00009380
2101	ESRRA, ERR1, ERRa, ERRalpha, ESRL1, NR3B1	estrogen-related receptor alpha	C00009380
2103	ESRRB, DFNB35, ERR2, ERRb, ESRL2, NR3B2	estrogen-related receptor beta	C00009380
2104	ESRRG, ERR3, ERRgamma, NR3B3	estrogen-related receptor gamma	C00009380
56776	FMN2	formin 2	C00009380
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00009380
9687	GREB1	growth regulation by estrogen in breast cancer 1	C00009380
3284	HSD3B2, HSD3B, HSDB, SDR11E2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (EC:1.1.1.145 5.3.3.1)	C00009380
7866	IFRD2, IFNRP, SKMc15, SM15	interferon-related developmental regulator 2	C00009380
3480	IGF1R, CD221, IGFIR, IGFR, JTK13	insulin-like growth factor 1 receptor (EC:2.7.10.1)	C00009380
3487	IGFBP4, BP-4, HT29-IGFBP, IBP4, IGFBP-4	insulin-like growth factor binding protein 4	C00009380
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00009380
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00009380
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00009380
26145	IRF2BP1	interferon regulatory factor 2 binding protein 1	C00009380
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00009380
26251	KCNG2, KCNF2, KV6.2	potassium voltage-gated channel, subfamily G, member 2	C00009380
354	KLK3, APS, KLK2A1, PSA, hK3	kallikrein-related peptidase 3 (EC:3.4.21.77)	C00009380
27074	LAMP3, CD208, DC_LAMP, DC-LAMP, DCLAMP, LAMP, LAMP-3, TSC403	lysosomal-associated membrane protein 3	C00009380
4199	ME1, HUMNDME, MES	malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40)	C00009380
4502	MT2A, MT2	metallothionein 2A	C00009380
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00009380
10499	NCOA2, GRIP1, KAT13C, NCoA-2, SRC2, TIF2, bHLHe75	nuclear receptor coactivator 2	C00009380
4824	NKX3-1, BAPX2, NKX3, NKX3.1, NKX3A	NK3 homeobox 1	C00009380
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00009380
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00009380
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00009380
8204	NRIP1, RIP140	nuclear receptor interacting protein 1	C00009380
56944	OLFML3, HNOEL-iso, OLF44	olfactomedin-like 3	C00009380
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00009380
5111	PCNA	proliferating cell nuclear antigen	C00009380
64236	PDLIM2, MYSTIQUE, SLIM	PDZ and LIM domain 2 (mystique)	C00009380
5174	PDZK1, CAP70, CLAMP, NHERF-3, NHERF3, PDZD1	PDZ domain containing 1	C00009380
5241	PGR, NR3C3, PR	progesterone receptor	C00009380
5411	PNN, DRS, DRSP, SDK3, memA	pinin, desmosome associated protein	C00009380
10957	PNRC1, B4-2, PNAS-145, PROL2, PRR2	proline-rich nuclear receptor coactivator 1	C00009380
5458	POU4F2, BRN3.2, BRN3B, Brn-3b	POU class 4 homeobox 2	C00009380
5580	PRKCD, MAY1, PKCD, nPKC-delta	protein kinase C, delta (EC:2.7.10.2 2.7.11.13)	C00009380
11098	PRSS23, SIG13, SPUVE, ZSIG13	protease, serine, 23	C00009380
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00009380
10257	ABCC4, EST170205, MOAT-B, MOATB, MRP4	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	C00009380
5932	RBBP8, COM1, CTIP, JWDS, RIM, SAE2, SCKL2	retinoblastoma binding protein 8	C00009380
6197	RPS6KA3, CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RSK2, S6K-alpha3, p90-RSK2, pp90RSK2	ribosomal protein S6 kinase, 90kDa, polypeptide 3 (EC:2.7.11.1)	C00009380
81537	SGPP1, SPPase1	sphingosine-1-phosphate phosphatase 1	C00009380
6558	SLC12A2, BSC, BSC2, NKCC1	solute carrier family 12 (sodium/potassium/chloride transporter), member 2	C00009380
7153	TOP2A, TOP2, TP2A	topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3)	C00003741
8140	SLC7A5, 4F2LC, CD98, D16S469E, E16, LAT1, MPE16, hLAT1	solute carrier family 7 (amino acid transporter light chain, L system), member 5	C00009380
6781	STC1, STC	stanniocalcin 1	C00009380
27347	STK39, DCHT, PASK, SPAK	serine threonine kinase 39 (EC:2.7.11.1)	C00009380
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00009380
6818	SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1)	C00009380
6870	TACR3, HH11, NK-3R, NK3R, NKR, TAC3RL	tachykinin receptor 3	C00009380
7031	TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2	trefoil factor 1	C00009380
7041	TGFB1I1, ARA55, HIC-5, HIC5, TSC-5	transforming growth factor beta 1 induced transcript 1	C00009380
7130	TNFAIP6, TSG-6, TSG6	tumor necrosis factor, alpha-induced protein 6	C00009380
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00009380
9537	TP53I11, PIG11	tumor protein p53 inducible protein 11	C00009380
7164	TPD52L1, D53, hD53	tumor protein D52-like 1	C00009380
7345	UCHL1, NDGOA, PARK5, PGP_9.5, PGP9.5, PGP95, Uch-L1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (EC:3.4.19.12)	C00009380
7150	TOP1, TOPI	topoisomerase (DNA) I (EC:5.99.1.2)	C00003741
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00003741
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00003741
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00003741
581	BAX, BCL2L4	BCL2-associated X protein	C00003741
7367	UGT2B17, BMND12, UDPGT2B17	UDP glucuronosyltransferase 2 family, polypeptide B17 (EC:2.4.1.17)	C00009380
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00009380
2023	ENO1, ENO1L1, MPB1, NNE, PPH	enolase 1, (alpha) (EC:4.2.1.11)	C00002668
329	BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1	baculoviral IAP repeat containing 2	C00006925
330	BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2	baculoviral IAP repeat containing 3	C00006925
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00006925
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00006925

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