Medicago truncatula
Species
KNApSAcK Entry
| Organism name | Medicago truncatula |
|---|---|
| Genus | Medicago |
| Family | Fabaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Medicago truncatula |
|---|---|
| Linked NCBI taxonomy ID | 3880 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Fabaceae |
|---|---|
| ID | 3803 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (23)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00006229
|
Vicenin 2
/ Apigenin 6,8-di-C-glucoside |
CHEMBL1442950
|
6 / 14 / 8 | No. 1 | No. 15 |
|
||
|
C00002518
|
Daidzin
/ Daidzoside / Daidzein 7-O-glucoside |
CHEMBL486422
|
C013908
|
11 / 18 / 41 | 3 / 2 | No. 2 | No. 15 |
|
|
C00010117
|
Bichanin A 7-O-glucoside-6''-malonate
/ Biochanin A 7-O-beta-D-glucoside-6''-O-malonate |
No. 2 | No. 15 |
|
||||
|
C00002553
|
Ononin
/ Formononetin 7-O-glucoside |
CHEMBL465980
|
11 / 14 / 40 | No. 2 | No. 15 |
|
||
|
C00010112
|
Sissotrin
/ Astroside / Biochanin A 7-O-glucoside |
CHEMBL557296
CHEMBL1405026 |
7 / 12 / 38 | No. 2 | No. 15 |
|
||
|
C00010125
|
Kakkalidone
/ Irisolidone 7-O-glucoside / Irisolidone 7-O-beta-D-glucoside |
No. 2 | No. 15 |
|
||||
|
C00010110
|
Genistein 7-O-glucoside-6''-malonate
/ Genistein 7-O-beta-D-glucoside 6''-O-malonate |
No. 2 | No. 15 |
|
||||
|
C00002528
|
Genistin
/ Genistoside / Genistein 7-O-glucoside / Genistein 7-O-beta-glucopyranoside |
CHEMBL486625
CHEMBL1364260 |
C040641
|
15 / 32 / 53 | 6 / 2 | No. 2 | No. 15 |
|
|
C00010083
|
Formononetin 7-O-(6''-malonylglucoside)
/ Formononetin 7-O-glucoside-6''-malonate / Formononetin 7-O-beta-D-glucoside-6''-O-malonate |
No. 2 | No. 15 |
|
||||
|
C00001071
|
Myricetin
|
CHEMBL164
|
C040015
|
78 / 70 / 56 | 39 / 2 | No. 3 | No. 15 |
|
|
C00013329
|
Tricin
/ 5,7,4'-Trihydroxy-3',5'-dimethoxyflavone / 5,7-Dihydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL454320
|
C017769
|
No. 3 | No. 15 |
|
||
|
C00002525
|
Formononetin
/ 7-Hydroxy-4'-methoxyisoflavone |
CHEMBL242341
|
C007768
|
24 / 36 / 58 | 13 / 0 | No. 3 | No. 15 |
|
|
C00014669
|
Hovetrichoside C
/ Maesopsin 4-O-glucoside / 2,4,6,4'-Tetrahydroxy-2-benzylcoumaranone 4-O-glucoside |
No. 12 | No. 14 |
|
||||
|
C00000256
|
Soyasapogenol B
|
CHEMBL153969
CHEMBL1762007 |
C407096
|
1 / 0 / 0 | No. 13 | No. 51 |
|
|
|
C00000982
|
Naringenin
/ (-)-Naringenin |
CHEMBL9352
CHEMBL32571 |
C005273
|
57 / 46 / 40 | 35 / 10 | No. 25 | No. 14 |
|
|
C00000977
|
Liquiritigenin
|
CHEMBL252642
CHEMBL271939 |
C083152
|
5 / 4 / 4 | 1 / 1 | No. 25 | No. 14 |
|
|
C00002507
|
Castanin
/ Afromosin / Afrormosin / 7-Hydroxy-6,4'-dimethoxyisoflavone |
CHEMBL464404
|
C080240
|
7 / 14 / 39 | 1 / 0 | No. 35 | No. 15 |
|
|
C00002547
|
(-)-Medicarpin
/ 3-Hydroxy-9-methoxypterocarpan |
CHEMBL238845
CHEMBL413297 |
C047353
|
3 / 1 / 1 | No. 66 | No. 15 |
|
|
|
C00003800
|
7,4'-Dihydroxyflavone
|
CHEMBL294878
|
C085172
|
17 / 19 / 16 | No. 76 | No. 15 |
|
|
|
C00006925
|
Isoliquiritigenin
|
CHEMBL129795
CHEMBL1395334 |
C040920
|
59 / 83 / 90 | 12 / 3 | No. 92 | No. 13 |
|
|
C00030299
|
Euodionoside F
/ Foliasalacioside A2 / 13-Hydroxyblumenol C 9-O-beta-glucoside |
No. 225 |
|
|||||
|
C00006117
|
Pterosupin
|
C083153
|
No. 261 | No. 14 |
|
|||
|
C00010183
|
Medicarpin 3-O-glucoside
/ Medicarpin 3-O-beta-D-glucoside |
CHEMBL517330
|
No. 557 | No. 15 |
|
Human Protein / Gene in interactions
151 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00002507 C00002518 C00002525 C00002528 C00002553 C00006925 C00010112 | 7 / 37 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00002507 C00002518 C00002525 C00002528 C00002553 C00010112 | 4 / 2 |
| O75496 | Geminin | Unclassified protein | C00000256 C00000982 C00002507 C00002528 C00002547 C00006925 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00002507 C00002518 C00002528 C00002553 C00006925 C00010112 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00002525 C00002528 C00002547 C00002553 C00006925 C00010112 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000982 C00001071 C00002525 C00003800 C00006925 | 0 / 1 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000982 C00001071 C00002525 C00003800 C00006925 | 3 / 3 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00002507 C00002518 C00002528 C00002553 C00010112 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00001071 C00002525 C00002528 C00003800 C00006925 | 2 / 2 |
| O00255 | Menin | Unclassified protein | C00000982 C00001071 C00002525 C00006925 | 2 / 5 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00002518 C00002525 C00002528 C00003800 | 4 / 1 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00002518 C00002528 C00002553 C00010112 | 1 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000982 C00001071 C00002553 C00006925 | 0 / 0 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00000977 C00000982 C00001071 C00003800 | 2 / 2 |
| P04062 | Glucosylceramidase | Enzyme | C00000982 C00001071 C00006229 C00006925 | 6 / 4 |
| P15121 | Aldose reductase | Enzyme | C00000982 C00001071 C00002553 C00006925 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000982 C00001071 C00002525 C00006925 | 1 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001071 C00002525 C00003800 C00006229 | 0 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000982 C00001071 C00002525 C00006925 | 1 / 2 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00000982 C00002525 C00003800 C00006925 | 5 / 3 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000982 C00001071 C00002525 C00006925 | 0 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000982 C00001071 C00002525 C00006925 | 1 / 1 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001071 C00002518 C00006925 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001071 C00006229 C00006925 | 0 / 0 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00000982 C00002525 C00003800 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00000982 C00001071 C00006925 | 0 / 0 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00000982 C00002525 C00003800 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000982 C00001071 C00006925 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00002507 C00002528 C00006925 | 1 / 0 |
| P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | C00002518 C00002553 C00003800 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00001071 C00002525 C00006925 | 4 / 3 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001071 C00006229 C00006925 | 0 / 0 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00002518 C00002553 C00003800 | 1 / 1 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000977 C00000982 C00006925 | 0 / 0 |
| P33527 | Multidrug resistance-associated protein 1 | drugs | C00000982 C00001071 C00002525 | 0 / 0 |
| P05091 | Aldehyde dehydrogenase, mitochondrial | Oxidoreductase | C00002518 C00002553 C00003800 | 1 / 1 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00001071 C00002518 C00006925 | 0 / 0 |
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00000982 C00001071 C00002525 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00000982 C00001071 C00006925 | 0 / 3 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001071 C00002525 C00003800 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00001071 C00006925 | 0 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00000982 C00001071 | 1 / 0 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00000982 C00001071 | 1 / 1 |
| P54132 | Bloom syndrome protein | Enzyme | C00001071 C00006925 | 1 / 2 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00001071 C00006925 | 5 / 2 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00001071 C00002528 | 1 / 0 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00002528 C00006925 | 1 / 8 |
| P02545 | Prelamin-A/C | Unclassified protein | C00002528 C00006925 | 11 / 10 |
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00001071 C00006925 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00001071 C00006925 | 2 / 3 |
| Q92887 | Canalicular multispecific organic anion transporter 1 | Unclassified protein | C00000982 C00001071 | 1 / 1 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00001071 C00006925 | 0 / 0 |
| Q9Y3R4 | Sialidase-2 | Enzyme | C00001071 C00003800 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00000977 C00006925 | 2 / 2 |
| P05412 | Transcription factor AP-1 | Transcription Factor | C00000977 C00006925 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00003800 C00006925 | 0 / 0 |
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00000982 C00001071 | 2 / 0 |
| P36888 | Receptor-type tyrosine-protein kinase FLT3 | Pdgfr | C00000982 C00001071 | 1 / 1 |
| P04745 | Alpha-amylase 1 | Enzyme | C00000982 C00001071 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00001071 C00006925 | 0 / 0 |
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00000982 C00001071 | 4 / 4 |
| Q04760 | Lactoylglutathione lyase | Enzyme | C00000982 C00001071 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00001071 C00006925 | 0 / 0 |
| P40225 | Thrombopoietin | Unclassified protein | C00001071 C00006925 | 1 / 1 |
| Q99700 | Ataxin-2 | Unclassified protein | C00001071 C00006925 | 1 / 1 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00000982 C00001071 | 1 / 1 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00001071 C00002528 | 0 / 0 |
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00002525 C00006925 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001071 C00002525 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00002528 C00002547 | 1 / 1 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00006925 C00010112 | 0 / 0 |
| P42345 | Serine/threonine-protein kinase mTOR | Enzyme | C00001071 C00006925 | 0 / 0 |
| Q04206 | Transcription factor p65 | Transcription Factor | C00000977 C00006925 | 0 / 0 |
| Q02880 | DNA topoisomerase 2-beta | Isomerase | C00001071 | 0 / 0 |
| P09923 | Intestinal-type alkaline phosphatase | Enzyme | C00001071 | 0 / 0 |
| P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | Enzyme | C00001071 | 3 / 1 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00001071 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00006229 | 7 / 3 |
| Q14790 | Caspase-8 | C14 | C00001071 | 2 / 1 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00001071 | 0 / 0 |
| Q9NPD5 | Solute carrier organic anion transporter family member 1B3 | Electrochemical transporter | C00000982 | 1 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00000982 | 0 / 1 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00000982 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00000982 | 0 / 1 |
| P06213 | Insulin receptor | TK tyrosine-protein kinase INSR subfamily | C00001071 | 5 / 4 |
| P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00000982 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00006925 | 2 / 0 |
| P16152 | Carbonyl reductase [NADPH] 1 | Enzyme | C00000982 | 0 / 0 |
| P12931 | Proto-oncogene tyrosine-protein kinase Src | Src | C00006925 | 0 / 0 |
| P06276 | Cholinesterase | Hydrolase | C00001071 | 0 / 0 |
| P06280 | Alpha-galactosidase A | Enzyme | C00003800 | 1 / 1 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00001071 | 0 / 0 |
| P35968 | Vascular endothelial growth factor receptor 2 | Vegfr | C00006925 | 1 / 0 |
| P04278 | Sex hormone-binding globulin | Secreted protein | C00000982 | 0 / 0 |
| P08581 | Hepatocyte growth factor receptor | TK tyrosine-protein kinase MET subfamily | C00006925 | 2 / 3 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00002507 | 2 / 2 |
| P10696 | Alkaline phosphatase, placental-like | Enzyme | C00001071 | 0 / 1 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00001071 | 0 / 0 |
| Q15746 | Myosin light chain kinase, smooth muscle | Mlck | C00001071 | 1 / 1 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00000982 | 2 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00000982 | 0 / 0 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00001071 | 0 / 0 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00001071 | 0 / 0 |
| Q9HC97 | G-protein coupled receptor 35 | Kynurenic acid receptor | C00001071 | 0 / 0 |
| O75828 | Carbonyl reductase [NADPH] 3 | Enzyme | C00000982 | 0 / 0 |
| Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00000982 | 0 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00000982 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00000982 | 1 / 1 |
| P24864 | G1/S-specific cyclin-E1 | Other cytosolic protein | C00000982 | 0 / 2 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00000982 | 0 / 0 |
| P11362 | Fibroblast growth factor receptor 1 | Fgfr | C00006925 | 4 / 5 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00006925 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00001071 | 1 / 1 |
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00000982 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00000982 | 1 / 0 |
| P37059 | Estradiol 17-beta-dehydrogenase 2 | Enzyme | C00000982 | 0 / 0 |
| P11309 | Serine/threonine-protein kinase pim-1 | Pim | C00001071 | 0 / 0 |
| P37840 | Alpha-synuclein | Unclassified protein | C00006925 | 4 / 2 |
| Q15046 | Lysine--tRNA ligase | Enzyme | C00001071 | 2 / 1 |
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00006925 | 1 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00001071 | 0 / 0 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00001071 | 0 / 0 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00000982 | 5 / 1 |
| P62158 | Calmodulin | Unclassified protein | C00000982 | 1 / 0 |
| P28907 | ADP-ribosyl cyclase 1 | Enzyme | C00001071 | 0 / 1 |
| P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Enzyme | C00001071 | 9 / 1 |
| P10275 | Androgen receptor | NR3C4 | C00000982 | 3 / 4 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00006229 | 1 / 1 |
| P10721 | Mast/stem cell growth factor receptor Kit | Pdgfr | C00006925 | 4 / 3 |
| P21802 | Fibroblast growth factor receptor 2 | TK tyrosine-protein kinase TLK subfamily | C00006925 | 9 / 3 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00003800 | 0 / 1 |
| P06746 | DNA polymerase beta | Enzyme | C00001071 | 0 / 0 |
| P49888 | Estrogen sulfotransferase | Enzyme | C00000982 | 0 / 0 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00006925 | 2 / 2 |
| P14618 | Pyruvate kinase PKM | Enzyme | C00006925 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00001071 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00001071 | 2 / 0 |
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00000982 | 0 / 0 |
| O94956 | Solute carrier organic anion transporter family member 2B1 | Unclassified protein | C00000982 | 0 / 0 |
| P31941 | DNA dC->dU-editing enzyme APOBEC-3A | Enzyme | C00001071 | 0 / 0 |
| Q9Y6L6 | Solute carrier organic anion transporter family member 1B1 | Electrochemical transporter | C00000982 | 1 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00001071 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00001071 | 1 / 4 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00006925 | 0 / 0 |
| P31639 | Sodium/glucose cotransporter 2 | Glucose | C00002525 | 1 / 1 |
| P13866 | Sodium/glucose cotransporter 1 | Glucose | C00002525 | 1 / 1 |
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00000982 | 3 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00001071 | 2 / 1 |
| P51531 | Probable global transcription activator SNF2L2 | Unclassified protein | C00006925 | 1 / 0 |
| P14061 | Estradiol 17-beta-dehydrogenase 1 | Enzyme | C00000982 | 0 / 0 |
| Q9HCT0 | Fibroblast growth factor 22 | Unclassified protein | C00001071 | 0 / 0 |
82 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00000982
C00001071
C00002507
C00002525
|
| 54577 | UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G | UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) |
C00000982
C00002525
C00006925
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00000982
C00001071
C00002525
|
| 54600 | UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I | UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) |
C00000982
C00002525
C00006925
|
| 54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) |
C00000982
C00002525
C00006925
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00000982
C00001071
C00002525
|
| 54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) |
C00000982
C00002525
C00006925
|
| 54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) |
C00000982
C00002525
C00006925
|
| 6513 | SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED | solute carrier family 2 (facilitated glucose transporter), member 1 |
C00000982
C00001071
C00006925
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00000982
C00001071
C00006925
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00000982
C00001071
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00000982
C00001071
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00000982
C00001071
|
| 3091 | HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
C00001071
C00002525
|
| 2100 | ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 | estrogen receptor 2 (ER beta) |
C00000982
C00002525
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00001071
C00006925
|
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00000982
C00002525
|
| 8505 | PARG, PARG99 | poly (ADP-ribose) glycohydrolase (EC:3.2.1.143) |
C00001071
|
| 1559 | CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 | cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00000982
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00000982
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00000982
|
| 3757 | KCNH2, ERG1, HERG, HERG1, Kv11.1, LQT2, SQT1 | potassium voltage-gated channel, subfamily H (eag-related), member 2 |
C00000982
|
| 5444 | PON1, ESA, MVCD5, PON | paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) |
C00000982
|
| 6566 | SLC16A1, HHF7, MCT, MCT1 | solute carrier family 16 (monocarboxylate transporter), member 1 |
C00000982
|
| 1588 | CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM | cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00000982
|
| 6817 | SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) |
C00000982
|
| 6818 | SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1) |
C00000982
|
| 405 | ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 | aryl hydrocarbon receptor nuclear translocator |
C00000982
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00000982
|
| 249 | ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP | alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1) |
C00000982
|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00000982
|
| 8644 | AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS | aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357) |
C00000982
|
| 1645 | AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB | aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112) |
C00000982
|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00000982
|
| 7366 | UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 | UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) |
C00000982
|
| 5243 | ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) |
C00002525
|
| 2056 | EPO, EP, MVCD2 | erythropoietin |
C00002525
|
| 10057 | ABCC5, ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
C00000982
|
| 217 | ALDH2, ALDH-E2, ALDHI, ALDM | aldehyde dehydrogenase 2 family (mitochondrial) (EC:1.2.1.3) |
C00002518
|
| 2353 | FOS, AP-1, C-FOS, p55 | FBJ murine osteosarcoma viral oncogene homolog |
C00002518
|
| 5241 | PGR, NR3C3, PR | progesterone receptor |
C00002518
|
| 1244 | ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
C00001071
|
| 397 | ARHGDIB, D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2 | Rho GDP dissociation inhibitor (GDI) beta |
C00001071
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00001071
|
| 847 | CAT | catalase (EC:1.11.1.6) |
C00001071
|
| 891 | CCNB1, CCNB | cyclin B1 |
C00001071
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00001071
|
| 1031 | CDKN2C, INK4C, p18, p18-INK4C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
C00001071
|
| 1312 | COMT | catechol-O-methyltransferase (EC:2.1.1.6) |
C00001071
|
| 1499 | CTNNB1, CTNNB, MRD19, armadillo | catenin (cadherin-associated protein), beta 1, 88kDa |
C00001071
|
| 54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00001071
|
| 1786 | DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT | DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37) |
C00001071
|
| 54583 | EGLN1, C1orf12, ECYT3, HIF-PH2, HIFPH2, HPH-2, HPH2, PHD2, SM20, ZMYND6 | egl-9 family hypoxia-inducible factor 1 (EC:1.14.11.29) |
C00001071
|
| 2203 | FBP1, FBP | fructose-1,6-bisphosphatase 1 (EC:3.1.3.11) |
C00001071
|
| 3082 | HGF, DFNB39, F-TCF, HGFB, HPTA, SF | hepatocyte growth factor (hepapoietin A; scatter factor) |
C00001071
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00001071
|
| 3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00001071
|
| 4233 | MET, AUTS9, HGFR, RCCP2, c-Met | met proto-oncogene (EC:2.7.10.1) |
C00001071
|
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00001071
|
| 4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00001071
|
| 4780 | NFE2L2, NRF2 | nuclear factor, erythroid 2-like 2 |
C00001071
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00000982
|
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00001071
|
| 8000 | PSCA, PRO232 | prostate stem cell antigen |
C00001071
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00001071
|
| 10257 | ABCC4, EST170205, MOAT-B, MOATB, MRP4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
C00000982
|
| 23411 | SIRT1, SIR2L1 | sirtuin 1 |
C00001071
|
| 7153 | TOP2A, TOP2, TP2A | topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) |
C00001071
|
| 9540 | TP53I3, PIG3 | tumor protein p53 inducible protein 3 |
C00001071
|
| 8626 | TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L | tumor protein p63 |
C00001071
|
| 7161 | TP73, P73 | tumor protein p73 |
C00001071
|
| 2539 | G6PD, G6PD1 | glucose-6-phosphate dehydrogenase (EC:1.1.1.49) |
C00002528
|
| 4489 | MT1A, MT1, MT1S, MTC | metallothionein 1A |
C00002528
|
| 4493 | MT1E, MT1, MTD | metallothionein 1E |
C00002528
|
| 4501 | MT1X, MT-1l, MT1 | metallothionein 1X |
C00002528
|
| 4502 | MT2A, MT2 | metallothionein 2A |
C00002528
|
| 7779 | SLC30A1, ZNT1, ZRC1 | solute carrier family 30 (zinc transporter), member 1 |
C00002528
|
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 |
C00006925
|
| 329 | BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1 | baculoviral IAP repeat containing 2 |
C00006925
|
| 330 | BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 | baculoviral IAP repeat containing 3 |
C00006925
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00006925
|
| 1831 | TSC22D3, DIP, DSIPI, GILZ, TSC-22R, hDIP | TSC22 domain family, member 3 |
C00000977
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (155)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #610251 | Alcohol sensitivity, acute |
P05091
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #207410 | Antley-bixler syndrome without genital anomalies or disordered steroidogenesis; abs2 |
P21802
|
| #613780 | Aortic aneurysm, familial thoracic 7; aat7 |
Q15746
|
| #101200 | Apert syndrome |
P21802
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #123790 | Beare-stevenson cutis gyrata syndrome; bstvs |
P21802
|
| #614592 | Bent bone dysplasia syndrome; bbds |
P21802
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| #210900 | Bloom syndrome; blm |
P54132
|
| %606641 | Body mass index; bmi |
P37231
|
| #114480 | Breast cancer |
P38398
P42336 |
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #300615 | Brunner syndrome |
P21397
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #607271 | Caspase 8 deficiency |
Q14790
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #613641 | Charcot-marie-tooth disease, recessive intermediate b; cmtrib |
Q15046
|
| #114500 | Colorectal cancer; crc |
P18054
P42336 P84022 Q14191 |
| #612918 | Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi |
P42336
|
| #615108 | Cowden syndrome 5; cws5 |
P42336
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
P22310 |
| #606785 | Crigler-najjar syndrome, type ii |
P22309
P22310 |
| #123500 | Crouzon syndrome |
P21802
|
| #613916 | Deafness, autosomal recessive 89; dfnb89 |
Q15046
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #610549 | Diabetes mellitus, insulin-resistant, with acanthosis nigricans |
P06213
|
| #125853 | Diabetes mellitus, noninsulin-dependent; niddm |
P06213
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #246200 | Donohue syndrome |
P06213
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #237500 | Dubin-johnson syndrome; djs |
Q92887
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #133239 | Esophageal cancer |
P04637
P18054 |
| #615363 | Estrogen resistance; estrr |
P03372
|
| #301500 | Fabry disease |
P06280
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #606764 | Gastrointestinal stromal tumor; gist |
P10721
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #143500 | Gilbert syndrome |
P22309
P22310 |
| #137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
| #231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
| #137760 | Glaucoma, primary open angle; poag |
Q16678
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P37231 |
| #606824 | Glucose/galactose malabsorption; ggm |
P13866
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #602089 | Hemangioma, capillary infantile |
P35968
|
| #114550 | Hepatocellular carcinoma |
P08581
P42336 |
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #237450 | Hyperbilirubinemia, rotor type; hblrr |
Q9NPD5
Q9Y6L6 |
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #609968 | Hyperinsulinemic hypoglycemia, familial, 5; hhf5 |
P06213
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #147950 | Hypogonadotropic hypogonadism 2 with or without anosmia; hh2 |
P11362
|
| #146300 | Hypophosphatasia, adult |
P05186
|
| #241510 | Hypophosphatasia, childhood |
P05186
|
| #241500 | Hypophosphatasia, infantile |
P05186
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #123150 | Jackson-weiss syndrome; jws |
P21802
|
| #182000 | Keratosis, seborrheic |
P42336
|
| #149730 | Lacrimoauriculodentodigital syndrome; ladd |
P21802
|
| #601626 | Leukemia, acute myeloid; aml |
P10721
P36888 |
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04637 Q14790 |
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #602501 | Megalencephaly-capillary malformation-polymicrogyria syndrome; mcap |
P42336
|
| #603387 | Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome; mpph |
P42336
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #601358 | Nicolaides-baraitser syndrome; ncbrs |
P51531
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #601665 | Obesity |
P37231
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #166250 | Osteoglophonic dysplasia; ogd |
P11362
|
| #167000 | Ovarian cancer |
P38398
P42336 |
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
P37840 |
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #604229 | Peters anomaly |
Q16678
|
| #101600 | Pfeiffer syndrome |
P11362
P21802 |
| #172700 | Pick disease of brain |
P10636
|
| #172800 | Piebald trait; pbt |
P10721
|
| #262190 | Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities |
P06213
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #605074 | Renal cell carcinoma, papillary, 1; rccp1 |
P08581
|
| #233100 | Renal glucosuria; glys1 |
P31639
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #609579 | Scaphocephaly, maxillary retrusion, and mental retardation |
P21802
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #273300 | Testicular germ cell tumor; tgct |
P10721
|
| #187950 | Thrombocythemia 1; thcyt1 |
P40225
|
| #190440 | Trigonocephaly 1; trigno1 |
P11362
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| #614916 | Ventricular tachycardia, catecholaminergic polymorphic, 4; cpvt4 |
P62158
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278300 | Xanthinuria, type i |
P47989
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (125)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04637 (related) P08581 (related) P21802 (related) P24864 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04637 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P04637 (related) |
| H00030 | Cervical cancer |
P00533
(related)
|
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) P24864 (related) |
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) Q15046 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04637 (related) Q92731 (marker) |
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
P37840 (related) |
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
P11511 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
P28907 (marker) |
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P14780 (related) P35354 (related) |
| H00027 | Ovarian cancer |
P04637
(related)
P38398 (related) P42336 (related) |
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
P38398 (related) |
| H00032 | Thyroid cancer |
P04637
(related)
P37231 (related) |
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
P08581 (related) P35354 (related) |
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
P08581 (related) |
| H01071 | Acute alcohol sensitivity |
P05091
(related)
|
| H00213 | Hypophosphatasia |
P05186
(related)
|
| H00719 | Leprechaunism |
P06213
(related)
|
| H00942 | Rabson-Mendenhall syndrome |
P06213
(related)
|
| H01228 | Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN) |
P06213
(related)
|
| H01267 | Familial hyperinsulinemic hypoglycemia (HHF) |
P06213
(related)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00023 | Testicular cancer |
P10696
(marker)
P10721 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
P10721
(related)
P10721 (marker) P36888 (related) Q01196 (related) Q01196 (marker) Q13951 (marker) |
| H00170 | Piebaldism |
P10721
(related)
|
| H00255 | Hypogonadotropic hypogonadism |
P11362
(related)
|
| H00443 | Osteoglophonic dysplasia (OD) |
P11362
(related)
|
| H00458 | Craniosynostosis |
P11362
(related)
P21802 (related) |
| H00516 | Isolated orofacial clefts |
P11362
(related)
|
| H01207 | Trigonocephaly |
P11362
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01261 | Congenital glucose-galactose malabsorption (GGM) |
P13866
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H00642 | Lacrimo-auriculo-dento-digital syndrome (LADD) |
P21802
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
Q92887 (related) |
| H01126 | Familial renal glucosuria (FRG) |
P31639
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
Q14191 (related) |
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00108 | Autoimmune lymphoproliferative syndromes (ALPS) |
Q14790
(related)
|
| H00801 | Familial thoracic aortic aneurysm and dissection (TAAD) |
Q15746
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00612 | Primary open angle glaucoma |
Q16678
(related)
|
| H01075 | Peters anomaly |
Q16678
(related)
|
| H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
| H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
Diseases related to CTD interactions
18 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D011471 | Prostatic Neoplasms |
C00002518
C00002528 |
| D009120 | Muscle Cramp |
C00006925
C00000977 |
| D009374 | Neoplasms, Experimental |
C00000982
|
| D056486 | Drug-Induced Liver Injury |
C00000982
|
| D064420 | Drug-Related Side Effects and Adverse Reactions |
C00000982
|
| D007674 | Kidney Diseases |
C00000982
|
| D008106 | Liver Cirrhosis, Experimental |
C00000982
|
| D008107 | Liver Diseases |
C00000982
|
| D009369 | Neoplasms |
C00000982
|
| D009202 | Cardiomyopathies |
C00000982
|
| D008569 | Memory Disorders |
C00002518
|
| D000647 | Amnesia |
C00000982
|
| D005909 | Glioblastoma |
C00001071
|
| D009203 | Myocardial Infarction |
C00001071
|
| D005831 | Genital Diseases, Female |
C00002528
|
| D001927 | Brain Diseases |
C00006925
|
| D001932 | Brain Neoplasms |
C00000982
|
| D009422 | Nervous System Diseases |
C00006925
|