KCF-S cluster No. 66 (62 metabolites)

Corresponding Phytochemical cluster No. 15

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (62)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

---

Cumulative plant class count

class name	count
rosids	487
Spermatophyta	1
asterids	1
Magnoliophyta	1

---

Cumulative family count

class name	count
Fabaceae	487
Pinaceae	1
Asteraceae	1
Myristicaceae	1
Merulinidae	1

KEGG BRITE br08003

---

Categories (1)

br08003 Category	# of metabolite
Pterocarpanes	8

---

metabolites link (8)

br08003 Category	KEGG ID	KNApSAcK ID
Pterocarpanes	C10461	C00002536
Pterocarpanes	C10502	C00002546
Pterocarpanes	C10503	C00002547
Pterocarpanes	C10508	C00002552
Pterocarpanes	C10531	C00002574
Pterocarpanes	C04271	C00009610
Pterocarpanes	C01729	C00018987
Pterocarpanes	C16229	C00019173

Metabolite list (62)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002536	Melilotocarpan A / 4-Hydroxyhomopterocarpin	CHEMBL480074
C00002546	Inermin / Maackiain / (-)-Maackiain / Demethylpterocarpin / 3-Hydroxy-8,9-methylenedioxypterocarpan	CHEMBL334918 CHEMBL239047 CHEMBL445279		3 / 2 / 3
C00002547	(-)-Medicarpin / 3-Hydroxy-9-methoxypterocarpan	CHEMBL238845 CHEMBL413297	C047353	3 / 1 / 1
C00002552	(-)-Nissolin
C00002574	(-)-Sparticarpin
C00009610	Demethylmedicarpin / 3,9-Dihydroxypterocarpan	CHEMBL238823 CHEMBL1098413	C042060
C00009611	Isomedicarpin / 9-Hydroxy-3-methoxypterocarpan
C00009612	4-Hydroxydemethylmedicarpin / 3,4,9-Trihydroxypterocarpan
C00009613	Baphinitone / (-)-Homopterocarpin / 3,9-Dimethoxypterocarpan	CHEMBL277682 CHEMBL396671 CHEMBL2007304
C00009614	Vesticarpan / 3,10-Dihydroxy-9-methoxypterocarpan	CHEMBL253263
C00009615	4-Hydroxymedicarpin	CHEMBL253466 CHEMBL450694
C00009616	Pterocarpin / 3-Methoxy-8,9-methylenedioxypterocarpan	CHEMBL21103 CHEMBL242128 CHEMBL1983713		7 / 8 / 10
C00009617	Methylnissolin / 3-Hydroxy-9,10-dimethoxypterocarpan
C00009618	2-Methoxymedicarpin
C00009619	4-Hydroxymaackiain / 3,4-Dihydroxy-8,9-methylenedioxypterocarpan	CHEMBL454850 CHEMBL490702
C00009620	4-Methoxymedicarpin / 3-Hydroxy-4,9-dimethoxypterocarpan	CHEMBL404648
C00009621	2-Hydroxyhomopterocarpin	CHEMBL465799
C00009622	2,3,9-Trimethoxypterocarpan	CHEMBL469708
C00009623	4-Methoxymaackiain	CHEMBL458847
C00009624	4-Hydroxypterocarpin	CHEMBL452773
C00009625	4-Methoxyhomopterocarpin
C00009626	Philenopteran / 3,9-Dihydroxy-7,10-dimethoxypterocarpan
C00009627	2,8-Dihydroxy-3,9-dimethoxypterocarpan
C00009628	Mucronucarpan / 2,10-Dihydroxy-3,9-dimethoxypterocarpan
C00009629	2-Methoxypterocarpin / 2,3-Dimethoxy-8,9-methylenedioxypterocarpan	CHEMBL465809
C00009630	4-Methoxypterocarpin	CHEMBL480288
C00009631	9-O-Methylphilenopteran / 3-Hydroxy-7,9,10-trimethoxypterocarpan
C00009632	Trifolian / 1,3-Dihydroxy-2-methoxy-8,9-methylenedioxypterocarpan
C00009633	4-Hydroxy-2,3,9-trimethoxypterocarpan
C00009634	2,8-Dihydroxy-3,9,10-trimethoxypterocarpan
C00009637	Neodunol
C00009638	Edulin / Neodulin	CHEMBL479690
C00009641	Ambonane
C00009646	Ficinin / 4-Methoxyneodulin
C00009740	Ambanol
C00009992	Nissicarpin / 3,7-Dihydroxy-9-methoxypterocarpan
C00009993	Fruticarpin / 7-Hydroxy-3,9-dimethoxypterocarpan
C00009994	Kushenin / Lespedezol D1 / 3,9-Dihydroxy-8-methoxypterocarpan
C00009995	Desmocarpin / 1,9-Dihydroxy-3-methoxypterocarpan
C00009996	Nissolicarpin / 3,7-Dihydroxy-2,9-dimethoxypterocarpan
C00009997	Melilotocarpan B
C00009998	Melilotocarpan D / 4,10-Dihydroxy-3,9-dimethoxypterocarpan
C00009999	Melilotocarpan E / 4,9-Dihydroxy-3,10-dimethoxypterocarpan
C00010000	Melilotocarpan C / 4-Hydroxy-3,9,10-trimethoxypterocarpan
C00010001	Odoricarpan / 10-Hydroxy-3,4,9-trimethoxypterocarpan
C00010003	9-O-Methylneodunol
C00010006	(6aR,11aR)-3,8-Dihydroxy-9-methoxypterocarpan
C00010007	(6aR,11aR)-8-Hydroxy-3,9-dimethoxypterocarpan	CHEMBL283139
C00010008	2-Hydroxymaackiain / 2,3-Dihydroxy-8,9-methylenedioxypterocarpan	CHEMBL455617
C00010009	2-Hydroxy-4-methoxypterocarpin / 2-Hydroxy-3,4-dimethoxy-8,9-methylenedioxypterocarpan	CHEMBL444391
C00018915	Secundiflorol I / 3-Hydroxy-8,9-dimethoxypterocarpan	CHEMBL239005
C00018987	(+)-Medicarpin / (+)-(6aS,11aS)-Medicarpin	CHEMBL238845 CHEMBL413297		3 / 1 / 1
C00019069	Erysubin C / (6aR,11aR)-2-Carboxyaldehyde-9-hydroxy-3-methoxypterocarpan
C00019173	(+)-Maackiain / 3-Hydroxy-8,9-(methylenedioxy)pterocarpan	CHEMBL334918 CHEMBL239047 CHEMBL445279		3 / 2 / 3
C00019256	(-)-2,3,4-Trimethoxy-8,9-methylenedioxypterocarpan
C00019257	(-)-2-Methoxymaackiain
C00019419	Derricarpin
C00019710	(6aR,11aR)-10-Hydroxy-3,9-dimethoxypterocarpan
C00019711	(6aR,11aR)-3,9,10-Trimethoxypterocarpan
C00033504	(6aR,11aR)-Vesticarpan / (+)-(6aR,11aR)-Vesticarpan	CHEMBL253263
C00034738	Uncinacarpan / (-)-Uncinacarpan
C00038635	Brandisianin F	CHEMBL250890

Human Protein / Gene in interactions

11 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P13866	Sodium/glucose cotransporter 1	Glucose	C00002546 C00009616 C00019173	1 / 1
P31639	Sodium/glucose cotransporter 2	Glucose	C00002546 C00009616 C00019173	1 / 1
O75496	Geminin	Unclassified protein	C00002547 C00018987	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00002547 C00018987	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002546 C00019173	0 / 1
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00002547 C00018987	1 / 1
P28482	Mitogen-activated protein kinase 1	Erk	C00009616	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00009616	1 / 1
Q13951	Core-binding factor subunit beta	Unclassified protein	C00009616	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00009616	1 / 4
P10636	Microtubule-associated protein tau	Unclassified protein	C00009616	4 / 3

Related Diseases

Diseases related to proteins in ChEMBL interactions