PCIDB

KNApSAcK Metabolite C00009616

Index

Metabolite

Species

Human Protein
/ Gene in interactions

Related Diseases

Metabolite

KNApSAcK Entry

id	C00009616
Name	Pterocarpin / 3-Methoxy-8,9-methylenedioxypterocarpan
CAS RN	524-97-0
Standard InChI	InChI=1S/C17H14O5/c1-18-9-2-3-10-13(4-9)19-7-12-11-5-15-16(21-8-20-15)6-14(11)22-17(10)12/h2-6,12,17H,7-8H2,1H3
Standard InChI (Main Layer)	InChI=1S/C17H14O5/c1-18-9-2-3-10-13(4-9)19-7-12-11-5-15-16(21-8-20-15)6-14(11)22-17(10)12/h2-6,12,17H,7-8H2,1H3

Cluster

Phytochemical cluster	No. 15
KCF-S cluster	No. 66

Link

ChEMBL

By standard InChI	CHEMBL21103
By standard InChI Main Layer	CHEMBL21103 CHEMBL242128 CHEMBL1983713

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name	count
rosids	6

Family

family name	count
Fabaceae	6

List (7)

* NCBI

KNApSAcK organism	*ID	*family	*plant class	*kingdom
Baphia nitida	162666	Fabaceae	rosids	Viridiplantae
Onionis viscosa ssp. breviflora
Ononis viscosa subsp. breviflora	798057	Fabaceae	rosids	Viridiplantae
Pterocarpus spp.	100169	Fabaceae	rosids	Viridiplantae
Sophora angustifolia	3896	Fabaceae	rosids	Viridiplantae
Sophora substrata	3896	Fabaceae	rosids	Viridiplantae
Swartzia madagascariensis	53925	Fabaceae	rosids	Viridiplantae

Human Protein / Gene in interaction

7 ChEMBL Protein in interactions

accession	description	class description	compound	assay ID (# of activities)	# of diseases (OMIM / KEGG)
P13866	Sodium/glucose cotransporter 1	Glucose	CHEMBL242128	CHEMBL892510 (1)	1 / 1
P31639	Sodium/glucose cotransporter 2	Glucose	CHEMBL242128	CHEMBL892511 (1)	1 / 1
P28482	Mitogen-activated protein kinase 1	Erk	CHEMBL242128	CHEMBL1614521 (1)	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	CHEMBL242128	CHEMBL1614421 (1) CHEMBL1614502 (1)	4 / 3
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	CHEMBL242128	CHEMBL1614364 (1)	1 / 1
Q13951	Core-binding factor subunit beta	Unclassified protein	CHEMBL242128	CHEMBL1613933 (1)	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	CHEMBL242128	CHEMBL1613933 (1)	1 / 6

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM	preferred title	UniProt
#600274	Frontotemporal dementia; ftd	P10636
#606824	Glucose/galactose malabsorption; ggm	P13866
#260540	Parkinson-dementia syndrome	P10636
#172700	Pick disease of brain	P10636
#601399	Platelet disorder, familial, with associated myeloid malignancy	Q01196
#233100	Renal glucosuria; glys1	P31639
#607250	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1	Q9NUW8
#601104	Supranuclear palsy, progressive, 1; psnp1	P10636

KEGG DISEASE (10)

KEGG	disease name	UniProt
H00058	Amyotrophic lateral sclerosis (ALS)	P10636 (related)
H00077	Progressive supranuclear palsy (PSP)	P10636 (related)
H00078	Frontotemporal lobar degeneration (FTLD)	P10636 (related)
H01261	Congenital glucose-galactose malabsorption (GGM)	P13866 (related)
H01126	Familial renal glucosuria (FRG)	P31639 (related)
H00001	Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)	Q01196 (related) Q01196 (marker)
H00003	Acute myeloid leukemia (AML)	Q01196 (related) Q01196 (marker) Q13951 (marker)
H00004	Chronic myeloid leukemia (CML)	Q01196 (related)
H00978	Thrombocytopenia (THC)	Q01196 (related)
H00063	Spinocerebellar ataxia (SCA)	Q9NUW8 (related)